therapy selected pathologies case reports · pdf file0 non-invasive diagnostic techniques are:...

36
January 13+14 th , 2017 Introduction to THERAPY SELECTED PATHOLOGIES CASE REPORTS

Upload: vandieu

Post on 06-Feb-2018

217 views

Category:

Documents


2 download

TRANSCRIPT

Page 1: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

January 13+14th, 2017Introduction to

THERAPY SELECTED PATHOLOGIES CASE REPORTS

Page 2: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Which answer is wrong?

0 imaginative: computertomography is always non-invasive.

0 non-invasive diagnostic techniques are: clinicalexamination, blood pressure, urine probe, ECG, sonography.

0 minimal-invasive: blood probe, gastroscopy, colonoscopy.

0 invasive: puncture of: liquor, amniotic fluid, fineneedle puncture (cytology), biopsy (histology), angiography.

Page 3: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Which answer is wrong?

0 imaginative: computertomography is always non-invasive.

0 non-invasive diagnostic techniques are: clinicalexamination, blood pressure, urine probe, ECG, sonography.

0 minimal-invasive: blood probe, gastroscopy, colonoscopy.

0 invasive: puncture of: liquor, amniotic fluid, fineneedle puncture (cytology), biopsy (histology), angiography.

Page 4: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Introduction to THERAPY

dietetics behaviourpharmacologysurgery

Page 5: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Introduction to THERAPY

symptomaticcurativeconservativeoperative

Page 6: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

symptomatic therapy

symptoms and signs are treated withoutelimination of the reason of the disease

(painkiller eg.)palliative therapy/care: special threatmentat the terminal stage of a disease (cancer,

ALS etc.)

Page 7: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

curative therapy

reason can be eliminatedhealth will be restored

examples: operation of tumor, appendixetc.

antibiotics

Page 8: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

conservative therapy

non-operative therapy

examples: pharmacotherapy, physico- and physical

therapy, psychotherapy, dietics

Page 9: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

operative therapy

examples: surgical therapy

special form: radiation, gamma knife

Page 10: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Some therapeutical applications are not performed by physicians:

dietologyphysiotherapy

massage therapypsychotherapy

Page 11: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Exampels of diseases which should be treated with accompanying dietetics

diabetes mellitus (hyperglycemia)hyperlipidemiacardiovascular diseases (risc of arterioscerosis)hyperuricemia (gout: high level of uric acid: not to be confused with (hyper) uremia or hematuria)inborn metabolic disorderfood intolerances and allergiestreatment with anticoagulating medication (such as

Marcumar®) maintaining health

Page 12: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

behavior as therapeutic key factor

e.g.:all indications for behavioural therapypsychosomatic stress and burnout syndromework-life balancephysiotherapy

Page 13: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

movement as therapeutic key factorphysiotherapyorthopedic problemsrehabilitätioncardiovascular diseasesmethabolic syndrome, obesitaspsychiatric disorders

Page 14: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Psychotherapy

in many cases of psychiatric disorders

autoimmune diseases

cardio-vascular diseases

sexual disorders, erectile dysfunction

support of cancerous diseases

psychosomatic illnesses

support of relatives

Page 15: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

interdisciplinary

psychosomatics

psychooncology

psychocardiology

gynecological psychsomatics

Page 16: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

The biopsychosocial model

("BPS")

is a general model or approach stating that

biological, psychological, (which entails

thoughts, emotions, and behaviors), and

social (socio-economical, socio-

environmental, and cultural) factors, all play

a significant role in human functioning in

the context of disease or illness

Page 17: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Which answer is wrong?

0 Symptomatic therapy treats symptoms and signswithout elimination of the reason.

0 Curative therapy eliminates the reason andhealth will be restored.

0 Conservative therapy is the opposite toalternative therapy.

0 Conservative therapy is the opposite to operative therapy.

Page 18: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Which answer is wrong?

0 Symptomatic therapy treats symptoms and signswithout elimination of the reason.

0 Curative therapy eliminates the reason andhealth will be restored.

0 Conservative therapy is the opposite toalternative therapy.

0 Conservative therapy is the opposite to operative therapy.

Page 19: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Which answer is wrong?

0 Hyperglycemia, hyperlipidemia, hyperuricemia should be treated with accompanying dietetics.

0 Hyperglycemia, hyperlipidemia, hyperuricemia are inborn metabolic disorders and can not be treated withdietics.

0 Movement/physiotherpy is a therapeutic key factor in thecase of orthopedic problems and rehabilitationmedicine.

0 With the help of endurance movement hypertensionmedication can be reduced.

Page 20: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Which answer is wrong?

0 Hyperglycemia, hyperlipidemia, hyperuricemia should be treated with accompanying dietetics.

0 Hyperglycemia, hyperlipidemia, hyperuricemia are inborn metabolic disorders and can not be treated withdietics.

0 Movement/physiotherapy is a therapeutic key factor in thecase of orthopedic problems and rehabilitationmedicine.

0 With the help of endurance movement hypertensionmedication can be reduced.

Page 21: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

minor surgery:non-invasivechiropractic, massage, other externalapplicartion

major surgeryminimally invasive and invasive surgery in terms of biomedicine

Page 22: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

surgery:learned manual skill

direct interaction between patient andphysician

Page 23: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Surgery

Greek: χειρουργική cheirourgikē: composedof χείρ, "hand", and ἔργον, "work", Latin: chirurgiae, meaning "hand work"

Page 24: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

DEGREE OF INVASIVENESS

minimally-invasive surgeries, involves smaller outer incision(s) to insert miniaturized instruments within a

body cavity or structure, as e.g. in laparoscopic surgery. future of surgery:

minimally-invasive surgery techniques

open surgical procedure such as a laparotomy requires a large incision to access the area of interest.

Page 25: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Laparotomyinvolves a large incision to gain access into

the abdominal cavitiy

Laparoscopyinvolves small incisions to gain access into

the abdomen or pelvis

www. medicalexpo.de

Page 26: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

biomedical surgical methods

excision: complete removal of an organ, tissue or tumorincision: cut into a tissue

biopsy: sampling tissue for examinationpunction: with hollow needle to collect cells or liquids

extraction: removal, to pull out (tooth, baby during birth)extirpation: removal of (cancerous) organs or part of it

resection: partial removal of a bodily structureectomy: from Greek εκ-τομια = "act of cutting out"

ablatio: removal of material from the surface (breast)amputation: removal of a limb or protruding partstransplantation: moving a part to another location

rekonstruction: plastic-surgical rebuilding

Page 27: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

ablatio (mammae) removal of material from the surface (breast)

synonym:mastectomy

amputation of breast

Page 28: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

transplantation moving one part to another location

autograftAutografts are the transplant of tissue to the same person (e.g.: skin

grafts, vein extraction for coronary artery bypass surgery, storing blood in advance of surgery).

allograft and allotransplantationAn allograft is a transplant of an organ or tissue between two

genetically non-identical members of the same species.

xenograft and xenotransplantationA transplant of organs or tissue from one species to another. An

example is porcine heart valve transplant, which is quite common and successful.

Page 29: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

TYPES OF SURGERY

emergency surgerymust be done promptly to save life, limb, or functional capacity

explorative surgery performed to aid or confirm a diagnosis

cosmetic surgery is done to improve the appearance of an otherwise normal structure

by body part performed on one organ system or structure, classed by the organ,

organ system or tissue involved. Examples: cardiac, vascular, gastrointestinal or orthopedic surgery

Page 30: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

surgical equipment

Laser surgery involves use of a laser for cutting tissue instead of a scalpel or similar surgical instruments.

Microsurgery involves the use of an operating microscope for the surgeon to see small structures.

Robotic surgery makes use of a surgical robot, such as the Da Vinci surgical system, to control the instrumentation under the direction of the surgeon.

Page 31: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

discharge papers

reason for visit/admission, assignment, signs and symptomsanamnesis, status, laboratory resultshistology (benign-malignant, TNM)diagnosis (including diagnostic methods)therapy and course of diseasefurther therapyfurther controls

Page 32: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Case reportwomen, 56, two children, housewife, minijobs

Assignment: palpable node in the left breast (upper left quadrant), visible in mammography

Anamnesis: migraine headache (postmenopausal relief),postmenopausal hormone replacement therapy

Histology: invasive lobular carcinoma (T2N1M0),receptor status: estrogen positive, sentinel lymph nodepositive

Diagnosis: malignant neoplasm of breast (C50-C50)Therapy: mastectomy with reconstruction, axillary

lymphonodectomy, reconstruction, postoperative 20 single sessions radiotherapy (50 Gy IF), Tamoxifen 30 mg/d.

Further therapy: Tamoxifen 30 mg/d, citalopram 20 mg orally once a day.

Further controls: quarterly

Page 33: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Case reportwomen, 38, no children

Assignment: tired, painful menstruation, menorrhagia, pain during sexAnamnesis: unfulfilled desire to have children, miscarriage

Dysmenorrhea, palpable swelling of the uterus, sonographicallyproven uterus myomatosuslabor: anaemia (Hb 8,2g/dl)

Histology: --Diagnosis: three intramural fibroids (corpus 3x2cm, 1,5x2cm, fundus: 3x4cm)Therapy: laparascopical extirpation of myomaFurther controls: sonographical

Page 34: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Which answer is wrong?

0 Surgery is derived from Greek and Latin, meaning"hand work".

0 Minimally-invasive surgery techniques are developingrapidly.

0 Resection is the partial removal of a bodily structure.0 Transplantation always moves an organ from one

person to another one.

Page 35: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Which answer is wrong?

0 Surgery is derived from Greek and Latin, meaning"hand work".

0 Minimally-invasive surgery techniques are developingrapidly.

0 Resection is the partial removal of a bodily structure.0 Transplantation always moves an organ from one

person to another one.

Page 36: THERAPY SELECTED PATHOLOGIES CASE REPORTS · PDF file0 non-invasive diagnostic techniques are: clinical examination, blood pressure, urine probe, ECG, sonography. 0 minimal-invasive:

Which answer is wrong?

0 Reconstruction is the plastic-surgical rebuilding ofphysical structures.

0 Minimally-invasive surgeries, involves smaller outer incision(s) to insert miniaturized instruments within a body cavity.

0 Open surgical procedure such as a laparotomy requires a large incision to access the area of interest.

0 The Da Vinci surgical system controls the surgical team.