theories of dental caries
TRANSCRIPT
THEORIES OF DENTAL THEORIES OF DENTAL CARIESCARIES
BY: DR. KHURRAM ZAFARBY: DR. KHURRAM ZAFARwww.thedentalclinicpk.comwww.thedentalclinicpk.com
THEORIES OF DENTAL THEORIES OF DENTAL CARIESCARIES
The Acidogenic theoryThe Acidogenic theory
The Proteolytic theoryThe Proteolytic theory
Proteolysis chelation theoryProteolysis chelation theory
ACIDOGENIC THEORYACIDOGENIC THEORY
W.D Miller was the first well known W.D Miller was the first well known scientist and investigator of dental caries scientist and investigator of dental caries and published his results in 1882.and published his results in 1882.
According to him dental decay is a According to him dental decay is a chemoparasitic processchemoparasitic process
It is a two stage process there is It is a two stage process there is decalcification of the enamel which also decalcification of the enamel which also results in the destruction of the dentin. in results in the destruction of the dentin. in the second stage there is dissolution of the second stage there is dissolution of the softened residue of the enamel and the softened residue of the enamel and dentin. dentin.
ACIDOGENIC THEORYACIDOGENIC THEORY
In the first stage there is In the first stage there is destruction is done by the acid destruction is done by the acid attack where as the dissolution of attack where as the dissolution of the residue is carried by the the residue is carried by the proteolytic action of the bacteria's proteolytic action of the bacteria's
This whole process is supported by This whole process is supported by the presence of carbohydrates the presence of carbohydrates microorganisms and dental plaque microorganisms and dental plaque
PROTEOLYTIC THEORYPROTEOLYTIC THEORY
The evidence given by the acidogenic The evidence given by the acidogenic theory was considerable but it was theory was considerable but it was not conclusive, and alternative not conclusive, and alternative explanation was given in the form of explanation was given in the form of proteolytic theory.proteolytic theory.
Workers like “Heider, Bodecker Workers like “Heider, Bodecker (1878)and Abbott (1879) contributed (1878)and Abbott (1879) contributed considerably to this theory considerably to this theory
PROTEOLYTIC PROTEOLYTIC THEORYTHEORY There has been evidence that the There has been evidence that the
organic portion of the tooth plays an organic portion of the tooth plays an important role in the development of important role in the development of dental cariesdental caries
The are some enamel structure which The are some enamel structure which are made of the organic material such are made of the organic material such enamel lamelle and enamel rodsenamel lamelle and enamel rods
These structure prove to be the path These structure prove to be the path ways for the advancing microorganisms.ways for the advancing microorganisms.
PROTEOLYTIC PROTEOLYTIC THEORYTHEORY It has been established that enamel contains It has been established that enamel contains
0.56 % of organic matter of which 0.18% is 0.56 % of organic matter of which 0.18% is keratin and 0.17 % is a soluble protein keratin and 0.17 % is a soluble protein
Microorganisms invade the enamel lamelle Microorganisms invade the enamel lamelle and the acid produced by the bacteria's and the acid produced by the bacteria's causes damage to the organic pathways in causes damage to the organic pathways in advance advance
The production of the yellowish pigment The production of the yellowish pigment produced by the proteolytic bacteria’s the produced by the proteolytic bacteria’s the presence of this pigment was only possible in presence of this pigment was only possible in the presence of dietary carbohydrates.the presence of dietary carbohydrates.
PROTEOLYSIS PROTEOLYSIS CHELATION THEORYCHELATION THEORY
Some of the minor flaws of the Some of the minor flaws of the acidogenic and the proteolytic acidogenic and the proteolytic theory were addressed in the theory were addressed in the proteolysis chelation theory.proteolysis chelation theory.
This theory was put forward by This theory was put forward by Schatz and his co-workers .Schatz and his co-workers .
PROTEOLYSIS PROTEOLYSIS CHELATION THEORYCHELATION THEORY
CHELATIONCHELATION It is a process in which there is It is a process in which there is
complexing of the metal ions to complexing of the metal ions to form complex substance form complex substance through coordinate covalent through coordinate covalent bond which results in:bond which results in:
poorly dissociated /orpoorly dissociated /or weakly ionized compoundweakly ionized compound
PROTEOLYSIS PROTEOLYSIS CHELATION THEORYCHELATION THEORY
Example of chelation reaction:Example of chelation reaction: Hemoglobin in which 4 pyrrole nuclei are linked to Hemoglobin in which 4 pyrrole nuclei are linked to
iron by a similar bondiron by a similar bond Chelation is independent of the PH of the Chelation is independent of the PH of the
medium.medium. The bacteria’s attack on the surface of the enamel The bacteria’s attack on the surface of the enamel
this is initiated by keratinolytic microorganisms this is initiated by keratinolytic microorganisms this result in the breakdown of the protein chiefly this result in the breakdown of the protein chiefly keratin and results in the formation of soluble keratin and results in the formation of soluble chelates which decalcify enamel even at neutral chelates which decalcify enamel even at neutral PHPH
Mucopolysaccarides may also act as secondary Mucopolysaccarides may also act as secondary chelators.chelators.
TYPES OF DENTAL TYPES OF DENTAL CARIESCARIES
Gv blanks classification of caries Gv blanks classification of caries classclass
I , II , III , IV , V and VII , II , III , IV , V and VI Rampant caries Rampant caries Recurrent cariesRecurrent caries Arrested cariesArrested caries Root or cemental cariesRoot or cemental caries Baby bottle caries Baby bottle caries