the future of nutrition: dairy ingredients

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Nutritional Ingredients: Factors for Success DAIRY INGREDIENTS SYMPOSIUM, San Francisco 3/18/08 Todd Runestad, Senior Editor, Functional Ingredients [email protected]

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How did antioxidants become a household word? Why are omega-3s in every new product launch? When did fiber break out of the retiree market? Are organic products taking over the world? How does dairy’s “healthy halo” improve its chances as the delivery system of choice for functional ingredients? What’s next – and how do I get in on it? See case studies showcasing how different sectors of the nutrition world found market success, and the factors that can be applied to the dairy field. From government pronouncements to scientific research, applications breakthroughs to riding the cultural Zeitgeist, opportunities to increase business are there for the taking – if you know where to look.

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Page 1: The Future of Nutrition: Dairy Ingredients

Nutritional Ingredients: Factors for Success

Nutritional Ingredients: Factors for SuccessDAIRY INGREDIENTS SYMPOSIUM, San Francisco

3/18/08

Todd Runestad, Senior Editor, Functional Ingredients

[email protected]

DAIRY INGREDIENTS SYMPOSIUM, San Francisco 3/18/08

Todd Runestad, Senior Editor, Functional Ingredients

[email protected]

Page 2: The Future of Nutrition: Dairy Ingredients

March 18-19, 2008 Hotel 480, San Francisco

Title of Presentation: Nutritional Ingredients: Factors for Success

Speaker Name: Todd Runestad Speaker Affiliation: Senior Editor, Functional Ingredients magazine, a nutrition industry trade publication serving

suppliers and manufacturers in the supplements, enhanced beverages and functional food sectors.

Brief Summary of Presentation (approximately 250 words or less): How did antioxidants become a household word? Why are omega-3s in every new product

launch? When did fiber break out of the retiree market? Are organic products taking over the world? How does dairy’s “healthy halo” improve its chances as the delivery system of choice for functional ingredients? What’s next – and how do I get in on it? Listen to case studies showcasing how different sectors of the nutrition world found market success, and the factors that can be applied to the dairy field. From government pronouncements to scientific research, applications breakthroughs to riding the cultural Zeitgeist, opportunities to increase business are there for the taking – if you know where to look.

March 18-19, 2008 Hotel 480, San Francisco

Title of Presentation: Nutritional Ingredients: Factors for Success

Speaker Name: Todd Runestad Speaker Affiliation: Senior Editor, Functional Ingredients magazine, a nutrition industry trade publication serving

suppliers and manufacturers in the supplements, enhanced beverages and functional food sectors.

Brief Summary of Presentation (approximately 250 words or less): How did antioxidants become a household word? Why are omega-3s in every new product

launch? When did fiber break out of the retiree market? Are organic products taking over the world? How does dairy’s “healthy halo” improve its chances as the delivery system of choice for functional ingredients? What’s next – and how do I get in on it? Listen to case studies showcasing how different sectors of the nutrition world found market success, and the factors that can be applied to the dairy field. From government pronouncements to scientific research, applications breakthroughs to riding the cultural Zeitgeist, opportunities to increase business are there for the taking – if you know where to look.

Page 3: The Future of Nutrition: Dairy Ingredients

Gloria and her healthful milk baths Gloria and her healthful milk baths

Page 4: The Future of Nutrition: Dairy Ingredients

Arch Intern Med. 2007 Aug 13-27;167(15):1610-8. A randomized factorial trial of vitamins C and E and beta carotene in the secondary prevention of

cardiovascular events in women: results from the Women's Antioxidant Cardiovascular Study. Cook NR, Albert CM, Gaziano JM, Zaharris E, MacFadyen J, Danielson E, Buring JE, Manson JE.

Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, 900 Commonwealth Ave E, Boston, MA 02215, USA. [email protected]

BACKGROUND: Randomized trials have largely failed to support an effect of antioxidant vitamins on the risk of cardiovascular disease (CVD). Few trials have examined interactions among antioxidants, and, to our knowledge, no previous trial has examined the individual effect of ascorbic acid (vitamin C) on CVD. METHODS: The Women's Antioxidant Cardiovascular Study tested the effects of ascorbic acid (500 mg/d), vitamin E (600 IU every other day), and beta carotene (50 mg every other day) on the combined outcome of myocardial infarction, stroke, coronary revascularization, or CVD death among 8171 female health professionals at increased risk in a 2 x 2 x 2 factorial design. Participants were 40 years or older with a history of CVD or 3 or more CVD risk factors and were followed up for a mean duration of 9.4 years, from 1995-1996 to 2005. RESULTS: A total of 1450 women experienced 1 or more CVD outcomes. There was no overall effect of ascorbic acid (relative risk [RR], 1.02; 95% CI, 0.92-1.13 [P = .71]), vitamin E (RR, 0.94; 95% CI, 0.85-1.04 [P = .23]), or beta carotene (RR, 1.02; 95% CI, 0.92-1.13 [P = .71]) on the primary combined end point or on the individual secondary outcomes of myocardial infarction, stroke, coronary revascularization, or CVD death. A marginally significant reduction in the primary outcome with active vitamin E was observed among the prespecified subgroup of women with prior CVD (RR, 0.89; 95% CI, 0.79-1.00 [P = .04]; P value for interaction, .07). There were no significant interactions between agents for the primary end point, but those randomized to both active ascorbic acid and vitamin E experienced fewer strokes (P value for interaction, .03). CONCLUSION: There were no overall effects of ascorbic acid, vitamin E, or beta carotene on cardiovascular events among women at high risk for CVD.

Arch Intern Med. 2007 Aug 13-27;167(15):1610-8. A randomized factorial trial of vitamins C and E and beta carotene in the secondary prevention of

cardiovascular events in women: results from the Women's Antioxidant Cardiovascular Study. Cook NR, Albert CM, Gaziano JM, Zaharris E, MacFadyen J, Danielson E, Buring JE, Manson JE.

Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, 900 Commonwealth Ave E, Boston, MA 02215, USA. [email protected]

BACKGROUND: Randomized trials have largely failed to support an effect of antioxidant vitamins on the risk of cardiovascular disease (CVD). Few trials have examined interactions among antioxidants, and, to our knowledge, no previous trial has examined the individual effect of ascorbic acid (vitamin C) on CVD. METHODS: The Women's Antioxidant Cardiovascular Study tested the effects of ascorbic acid (500 mg/d), vitamin E (600 IU every other day), and beta carotene (50 mg every other day) on the combined outcome of myocardial infarction, stroke, coronary revascularization, or CVD death among 8171 female health professionals at increased risk in a 2 x 2 x 2 factorial design. Participants were 40 years or older with a history of CVD or 3 or more CVD risk factors and were followed up for a mean duration of 9.4 years, from 1995-1996 to 2005. RESULTS: A total of 1450 women experienced 1 or more CVD outcomes. There was no overall effect of ascorbic acid (relative risk [RR], 1.02; 95% CI, 0.92-1.13 [P = .71]), vitamin E (RR, 0.94; 95% CI, 0.85-1.04 [P = .23]), or beta carotene (RR, 1.02; 95% CI, 0.92-1.13 [P = .71]) on the primary combined end point or on the individual secondary outcomes of myocardial infarction, stroke, coronary revascularization, or CVD death. A marginally significant reduction in the primary outcome with active vitamin E was observed among the prespecified subgroup of women with prior CVD (RR, 0.89; 95% CI, 0.79-1.00 [P = .04]; P value for interaction, .07). There were no significant interactions between agents for the primary end point, but those randomized to both active ascorbic acid and vitamin E experienced fewer strokes (P value for interaction, .03). CONCLUSION: There were no overall effects of ascorbic acid, vitamin E, or beta carotene on cardiovascular events among women at high risk for CVD.

Page 5: The Future of Nutrition: Dairy Ingredients

Nutrition Industry: Major Product SegmentsNutrition Industry: Major Product Segments

2005 ($Mil)

2006 ($Mil)

06 growt

hSupplements 21,316 22,460 5.4%

Natural & Organic Food 20,840 23,602 13.3%

Functional Foods 28,500 31,400 10.2%

Natural & Organic Personal Care, Household Goods

6,556 7,490 14.2%

Nutrition Industry 77,212 84,952 10.0%

Page 6: The Future of Nutrition: Dairy Ingredients

0

100

200

300

400

500

600

700

800

900

1000

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006Figure: in $Mil

U.S. Vitamin E Sales, 1997-2006 ($395 Mil in 2006) U.S. Vitamin E Sales, 1997-2006 ($395 Mil in 2006)

Page 7: The Future of Nutrition: Dairy Ingredients
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U.S. Calcium Sales, 1997-2006 ($1.0 Bil in 2006)

0

200

400

600

800

1000

1200

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006

Figure: in $Mil

Page 14: The Future of Nutrition: Dairy Ingredients
Page 15: The Future of Nutrition: Dairy Ingredients

As some perish … As some perish …

0

50

100

150

200

250

300

350

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006

Figure: in $Mil

U.S. St. John’s Wort Sales, 1997-2006 ($60 Mil in 2006) U.S. St. John’s Wort Sales, 1997-2006 ($60 Mil in 2006)

Page 16: The Future of Nutrition: Dairy Ingredients

Others prosper … Others prosper …

0

20

40

60

80

100

120

140

160

180

200

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006

Figure: in $Mil

U.S. Mangosteen Juice Sales, 1997-2006 ($147 Mil in 2006)U.S. Mangosteen Juice Sales, 1997-2006 ($147 Mil in 2006)

Page 17: The Future of Nutrition: Dairy Ingredients

23.70%

0.0%

5.0%

10.0%

15.0%

20.0%

25.0%

30.0%

1998 1999 2000 2001 2002 2003 2004 2005 2006

U.S. Sports & Energy Drink Sales Growth, 1998-2006U.S. Sports & Energy Drink Sales Growth, 1998-2006

Page 18: The Future of Nutrition: Dairy Ingredients
Page 19: The Future of Nutrition: Dairy Ingredients

Lactium-based Dreamerz sleep milk

Lactium-based Dreamerz sleep milk

Page 20: The Future of Nutrition: Dairy Ingredients

U.S. Specialty Supplements 2004 ($Mil) 2005 ($Mil) 2006 ($Mil) 06 growth

Glucosamine/Chondroitin 762 810 818 1.0%Homeopathics 532 619 673 8.7%Fish/Animal Oils 262 359 489 36.3%CoQ10 283 339 377 11.2%Probiotics 204 243 299 23.2%Plant Oils 177 197 228 15.5%Digestive Enzymes 147 166 182 9.5%MSM 111 107 102 -4.4%SAMe 93 96 98 1.6%Bee Products 81 91 95 4.5%Melatonin 67 73 81 10.6%5 HTP 59 68 79 15.7%DHEA 48 50 48 -3.2%Gelatin 52 48 43 -10.9%Others 134 148 177 20.3%Total 3,013 3,414 3,790 11.0%

U.S. Specialty Supplements 2004 ($Mil) 2005 ($Mil) 2006 ($Mil) 06 growth

Glucosamine/Chondroitin 762 810 818 1.0%Homeopathics 532 619 673 8.7%Fish/Animal Oils 262 359 489 36.3%CoQ10 283 339 377 11.2%Probiotics 204 243 299 23.2%Plant Oils 177 197 228 15.5%Digestive Enzymes 147 166 182 9.5%MSM 111 107 102 -4.4%SAMe 93 96 98 1.6%Bee Products 81 91 95 4.5%Melatonin 67 73 81 10.6%5 HTP 59 68 79 15.7%DHEA 48 50 48 -3.2%Gelatin 52 48 43 -10.9%Others 134 148 177 20.3%Total 3,013 3,414 3,790 11.0%

Page 21: The Future of Nutrition: Dairy Ingredients

U.S. Probiotic Sales, 1997-2006 ($299 Mil in 2006)

0

50

100

150

200

250

300

350

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006

Figure: in $Mil

Page 22: The Future of Nutrition: Dairy Ingredients

Get in the game!Get in the game!

U.S. Fish Oil Sales, 1997-2006 ($489 Mil in 2006)

0

100

200

300

400

500

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006

Figure: in $Mil

Page 23: The Future of Nutrition: Dairy Ingredients

Gov’t says / health claims / soy:Gov’t says / health claims / soy:

Page 24: The Future of Nutrition: Dairy Ingredients

Mass Market Vitamin E Sales, Dec 2003 to Jan 2006

$0

$2

$4

$6

$8

$10

$12

$14

$16

Dec Jan Feb Mar Apr May Jun Jul Aug Sep Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep Sep Oct Nov Dec Jan

$mil

in F

DM

sal

es

Source: IRI Four Week Periods

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