TheDiscoveryofDNA

FrederickGriffith(1928)TransformationPrincipleandHershey&Chase(1952)BlenderExperimentWatchthevideo:https://www.youtube.com/watch?v=EmKQGczeI6EWhatarebacteriacapableof?WhydidGriffithusepneumonia?Roughcoat=______________________.Smoothcoat=__________________________Mouseinjectedwiththeroughcoatwill__________________________Mouseinjectedwiththesmoothcoatwill__________________________Whathappensifthesmoothcoatbacteriaareheated?Whathappenedwiththeheattreatedsmoothbacteriawereinjectedintothemouse?______________Whatactuallyhappened????Hershey&ChaseSectionWhatdidtheythinkhereditywasdoneusing?_____________________

Drawasimplebacteriophageandlabelwhateachsectioniscomposedof.Howdobacteriophagesreproduce?Whatwillthegeneticmaterialtellthecelltodo?Howdidthelabeltheproteincoat? Howdidtheylabelthenucleicacid?Whydidtheyusetheblender?Whatwastheresultoftheirexperiment???

ErwinChargaff(1947)Chargoff’sRatioWatchthevideo:https://www.youtube.com/watch?v=HvJlnujmYcgExplainChargoff’sratio?AccordingtoChargoff,ifaDNAstrandiscomposedof15%adenine,whatpercentageoftheDNAiscomposedofcytosine?Meselson&Stahl(1958)TheSemi-ConservativeModelWatchthevideo:https://www.youtube.com/watch?v=JcUQ_TZCG0wBrieflydescribeeachofthemodelsofDNAreplicationbelowConservative-Semi-conservative-Dispersive-

RefertothediagrambelowHowdogeneration0andgeneration1differ?Explainthedensityresultsseeningenerations2,3,and4.WhatdidMeselsonandStahlconcludeaboutthemodelofDNAreplication?