tes mobile startupvillage
TRANSCRIPT
Development, creation and international launch of a line
of medical devices to treat sensorineural hearing
loss and tinnitus
TES MOBILE1
SUMMARY
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• Project aim: Development, certification and international market launch of a line of medical devices and a procedure to treat sensorineural hearing loss and tinnitus.
• Essence of the innovation: Implementing unique patented technology for selective transcranial electric stimulation of the brain’s protective mechanisms with an impulse current combined with acoustic influence by tonal signals.
• To be created during project realization: Professional and individual device versions; the latter will be in the form of a mobile application (for download and periodic update) and a special headset connected to user’s mobile platform (smartphone or tablet PC).
• Project budget (24 months): $ 1 335K
• Looking for: Partners for product promotion.
MEDICAL PROBLEM
• About 10 % of the world’s population suffer from hearing disorders
• In 2015 the number of patients will reach 700 million and there will be 900 million patients in 2020
• 85-90 % of patients have sensorineural hearing loss and 50 % have tinnitus
• This equals 30 million patients in the US, 80 million in Europe and 13 million in Russia
• Hearing loss and tinnitus have no specific treatment at present!
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THE SOLUTIONAudioselective Transcranial Electric Stimulation
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The biophysical basis is the proven positive impact of re-education in the treatment of acoustic neuronal disorders
Audio stimuli of variable frequency and intensity
Transcranial Electric Stimulation
Indiv
idu
al
Pro
fess
ion
al
PROTOTYPE AND RESULTSPrototype device – TRANSAIR-07.Course – 10-15 procedures, every other day.Results:• Hearing improved in 89 % of patients with
acute/sudden hearing loss and in 67 % of those with chronic hearing loss (regardless of etiology)
• Tinnitus stops or becomes milder in 91 % of patients
• Tonal hearing thresholds are stably decreased by 10-35 dB
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36% 55%9%
ATES effects on subjective tinnitusPercentage of patients with improved hearing
in acute and chronic SNHL
– Tinnitus stopped
– Tinnitus decreased in intensity
– Tinnitus remained unchanged
COMPETITIVE TECHNOLOGIES
Traditional drug and physical therapy
Histamine-like medicines, retroauricular procaine blocks, laser therapy, stimulation with fluctuating current, quantum hemotherapy, plasmapheresis, homeopathic medicines, etc.
Aimed to inhibit disease progression,
not to treat it
Tinnitus Retaining Therapy (TRT)
Use of special hearing devices combined with white noise generator. Widely used in the West, with a sales volume (therapy courses) in 2011 exceeding USD 87 million.
Does not treat the disease, but teaches the
patient to ignore it
Cochlear implants
These implants consist of wearable (external) and implanted (inner) parts. The costs of an operation start from USD 30,000. The market has topped USD 960 million and will reach USD 2.3 billion in 2017. The USA accounts for 40 % of the market.
Invasive hearing restoration applicable in severe hearing loss
only
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BUSINESS MODEL:Individual ATES
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purchasefee
recommendation
Purchase of SW updates fee
purchase
4 P
Insurance coverage
BUSINESS MODEL: Professional ATES
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advertise
mentfee
service
sale
Equipment and
consumables at wholesale
price
Equipment and consumables at market
price
MARKET AND SALES
• The market for hearing aids grows by 10-15 % a year, to reach USD 26.2 billion in 2017*
• USA, Europe, Canada, and Japan account for 80 % of sales. Within the last 5 years, the mobile device market in the US tripled (from USD 2.7 billion to 9.6 billion); 15 million devices were sold**
• Sales volume in 6yr. (est.) – $ 21,6M
* - Audiological Devices - Global Strategic Business Report** - HIMSS Analytics
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23.1 %
37.0 %
3.9 %
34.4 %
1.4 % 0.1 % Продажа индивидуальных АТЭС (без страхового покрытия)
Продажа индивидуальных АТЭС (со страховым покрытием)
Реализация профессиональных АТЭС
Комиссия с услуги по лечению СНТ и тиннитуса
Продажа обновлений ПО для индивидуального АТЭС
Продажа расходных материалов для профессионального АТЭС
Sales of individual ATES (without insurance coverage)
Sales of individual ATES (with insurance coverage)
Sales of professional ATES
Fees per services in SNHL and tinnitus treatment
Sales of software updates for individual ATES
Sales of consumables for professional ATES
THE TEAMAlexander Malygin – CEO, co-founder, Candidate of Technical Science, MBA, 20 years of business experience. He headed the organization of serial production, certification and technical testing of TRANSAIR and DOKTOR TES devices, participated in creating a sales and service network for the device. During his job, more than 5,000 and over 40,000 TRANSAIR and DOKTOR TES devices respectively have been sold and 10 regional agencies have been founded.
Prof. Valeriy Lebedev – Research Director, MD, co-founder, member of the Russian Academy of Natural Sciences. He discovered TES effects on protective systems in the brain of animals and humans. The author of 98 articles and 115 theses on TES therapy. An Honored Science Worker of the Russian Federation and Head of Applied Neurophysiology at the I.M. Sechenov Saint Petersburg Society of Physiologists, Biochemists and Pharmacologists.
Anna Belimova – physical therapist and audiologist, Candidate of Medicine,
10 years of experience in SNHL treatment. She has personally performed all clinical trials, arranged and partly performed instrumental testing, carried out ATES procedures in SNHL patients, and studied changes in hearing after ATES.
Dmitry Tseitlin – Business Development Director, MD, Candidate of Medicine, 20 years of experience in international marketing and technology commercialization in Russia, Israel and Germany. Business Coach at the Skolkovo Industrial Park.
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