technology innovation alert - technology innov… · accuracy changes in environment can affect the...

Interesting Innovation

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01 December – 15 December, 2018

Technology Innovation Alert

N o n - i n v a s i v e D i a b e t e s M o n i t o r i n g

ARTIFICIAL INTELLIGENCE IN BLOOD GLUCOSE LEVEL MEASURING

5 5 3 0 103

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Benefits of this Report

Technology Innovation Alert – Non-Invasive Diabetes Monitoring

• To get a complete information on patents published or granted in a particular technology

• To identify opportunities of patent/business acquisition

• To keep on top of R&D and Patenting activities of competitors, and align our own based on real time information

• Saves lot of time of in-house IP and R&D team

• The report is abstracted by experts of DexPatent in such a way that you can understand the gist of each important patent just by a glance

• Save Time, Save Cost and Remain Up-to-date

2

Highlights of the report


China

Most filed jurisdictionActive players

Prediktor Medical As.

Non-Invasive diabetes monitor type

Obtaining data from multiple sensors

3



• Shutang Information Tech

• I Sens

• Philips

Large companies

SMEs

• Phoenix silicon int corp

• Masimo corp

• Sensys medical

Start-ups

• Anhui Jianlang Medical

Devices

• Prediktor medical

• Shenzhen Manniu

Medical

• BIOEPIC

Players of this Report

4



Universities / Research centers

• Anhui jingzhun medical industry research

institute

• Lanzhou university first hospital

• Kwangwoon university industry-academic

cooperation

Players of this Report

5



Patents protected under

jurisdictions in this Report

WIPO

United States

China

Europe

Korea

6

Problems and its proposed solutions in this report


Inaccuracy, inconvenient to carry and detect

Simple, convenient, low cost, accuracy, avoid risk of wound infection

Costly and complex Improved apparatus and non-invasive method of measuring blood glucose level

7

Noisy laser diodeImprove the signal to noise ratio

Invasive measurement and accuracy problem

A non-invasive and accurate approach for the measurement of blood glucose level



8

Requiring lot of time for measuring glucose level

Real-time monitoring and improving the quality of medical care

Non-invasive method is complex and inaccurate measurement

Using artificial intelligence for improving accuracy

Changes in environment can

affect the operation of an LED.

Adjusting the current applied to led to ensure that light intensity is consistent regardless of ambient temperature

Invasive measurement leads to pain and infection

Non-invasive blood glucose meter for measuring blood sugar by sweat other than blood



9

Previous filter systems results in high/low glucose concentration than actual

Real time measurement of blood glucose level, and the measuring accuracy is improved.

Conventional non-invasive methods tends to be low accuracy

Improved non-invasive approach to measure concentration of a chemical constituent in a material

Conventional method is less convenient, not reliable, less accuracy

Smart sensor device, reliable, portable, low cost

Poor compliance, added cost of a disposable, one-use-only

Improved accuracy and precision of the noninvasive target analyte measurement in a tissue



10

Conventional blood glucose Measurements are inferior in accuracy

Economical, disposable(applicator),convenient maintenance

Inaccuracy Measurements Without psychological burden, without discomfort with higher accuracy.

Problem of pain and infection Non-invasive blood glucose meter for measuring blood sugar by sweat

Benefits of this Report


Technologies of non-invasive glucose monitor in this report

• Battery• Transmitter• LED light• Infrared LED• Optical sensor• Bio-impedance sensor• Calibrating model• Wrist band or strap• Wearable device• Acoustic sensor• Artificial intelligence• Body vitals• Environmental data• Artificial neural network• Wearable wrist band

• Fingertip optical sensor• Blood glucose sensor• Ear clip sensor• Medical modular bracelet• Level of attenuation of light to

calculate glucose in user blood• Gel-embedded glucose oxidase

enzyme layer• Applicator assembly integrated

with sensor module• Portable blood glucose

monitoring device • Wireless communication to

remote devices

• Reflectance or transmittance of light from a body part

• Obtaining data from multiple sensors

• Impedance-detecting apparatus• Voltage drop due to oxidation

reduction reaction• Near infrared light source • Photoelectric measurement

signal• Reflectance of signal from the• Transmitting the glucose values

to server

11

Patent Family Count


A portable non-invasive diabetes

detection device measuring blood

glucose concentration by obtaining data

from humidity, radiation, pressure, blood

oxygen parameter and temperature

sensors

DexPatent Abstract

0

Innovation Involves

✓ Portable blood glucose

monitoring device

✓ Obtaining data from multiple

sensors

Anhui Jingzhun Medical Industry

Research Institute

Portable blood glucose

monitoring device

C N 1 0 8 9 2 6 3 2 9

12

By Research Institute

https://worldwide.espacenet.com/publicationDetails/biblio?II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20181204&CC=CN&NR=108926329A&KC=A

Patent Family Count


A wearable mobile device to monitor

biomarker value (glucose) using artificial

neural network

DexPatent Abstract

2

Innovation Involves

✓ Wearable device

✓ Artificial Neural Network

✓ Wireless communication to

remote devices

13

Wearable device for glucose

level monitor

W O 2 0 1 8 2 2 0 0 5 2

13

By Company

https://epichealth.io/

https://worldwide.espacenet.com/publicationDetails/biblio?CC=WO&NR=2018220052A1&KC=A1&FT=D&ND=3&date=20181206&DB=&locale=en_EP

Patent Family Count


A wearable sensor for measuring

glucose level obtaining data from

gyroscope, acceleration, UV sensor,

optical heartrate sensor, temperature

sensor, blood oxygen sensors, glucose

sensor and skin response sensor

DexPatent Abstract

0

Innovation Involves

✓ Medical modular bracelet

✓ Obtaining data from multiple

sensors

Lanzhou University First Hospital

Wearable bracelet

C N 1 0 8 9 6 8 9 3 1

14

By University


Patent Family Count


A wrist worn optical sensor to measure

glucose level by the light reflected or

transmitted from the body part.

DexPatent Abstract

6

Innovation Involves

✓ LED light

✓ Reflectance or transmittance of

light from a body part

Wearable blood glucose monitor

E P 3 2 7 7 1 7 2

15

By Company

https://worldwide.espacenet.com/publicationDetails/biblio?CC=EP&NR=3277172B1&KC=B1&FT=D&ND=4&date=20181212&DB=&locale=en_EP

https://www.philips.co.in/

Patent Family Count


An artificial intelligence algorithm for

calculating glucose levels by utilizing

environmental data, user base data,

body vitals & glucose values

DexPatent Abstract

0

Innovation Involves

✓ Wearable

✓ Artificial intelligence

✓ Body vitals

✓ Environmental data

Blood glucose measuring device

Shenzhen Manniu Medical Co., Ltd.

C N 1 0 8 9 6 8 9 7 5

16

By Company

https://worldwide.espacenet.com/publicationDetails/biblio?CC=CN&NR=108968975A&KC=A&FT=D&ND=&date=20181211&DB=&locale=en_EP

Patent Family Count


E P 3 4 0 9 0 7 7

Medical analysis device with infra-red

LED and processor to estimate glucose

level in user's blood.

DexPatent Abstract

PREDIKTOR MEDICAL AS

3

Innovation Involves

✓ Infrared LED

✓ Level of attenuation of light to

estimate glucose in user blood

Non-invasive blood glucose level

measuring device

17

By Company

https://worldwide.espacenet.com/publicationDetails/biblio?II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20181205&CC=EP&NR=3409077A1&KC=A1

https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20180829&CC=EP&NR=3364819A1&KC=A1

Patent Family Count


C N 1 0 6 8 5 9 6 6 6

A blood glucose monitoring device for

obtaining the glucose level by the

reflectance of light from the human body

portion

DexPatent Abstract

Shutang Information Tech

0

Innovation Involves

✓ Reflectance of signal from the

portion of human body

✓ Near infrared light source

✓ Photoelectric measurement signal

Blood glucose monitoring device

18

By Company


Patent Family Count


E P 3 4 0 8 7 7 2

DexPatent Abstract

PREDIKTOR MEDICAL AS

3

Blood glucose monitoring device

Innovation Involves

✓ Optical sensor

✓ Bio-impedance sensor

✓ Calibration modelCalculating glucose level based on the first

and second intermediate estimate from the

first and second measured spectrum

19

By Company

https://worldwide.espacenet.com/publicationDetails/biblio?II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20181205&CC=EP&NR=3408772A1&KC=A1

Patent Family Count


C N 1 0 8 9 2 6 3 5 1

DexPatent Abstract

Anhui Jianlang Medical Devices

1

Wrist band or strap for calculating

glucose level

Innovation Involves

✓ Wrist band or strap

✓ Gel-embedded glucose oxidase

enzyme layerGlucose level in skin tissue is calculated by

the different electrical signal obtained from

the body

20

By Company


Patent Family Count


W O 2 0 1 8 2 2 2 0 1 6

DexPatent Abstract

I SENS INC

1

Innovation Involves

✓ Applicator assembly integrated

with sensor module

✓ Battery

✓ TransmitterA sensor module attached with applicator

assembly for monitoring glucose level

where the sensor module is attached to the

body by operating the applicator

Continuous glucose monitoring

21

By Company

https://worldwide.espacenet.com/publicationDetails/biblio?II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20181206&CC=WO&NR=2018222016A1&KC=A1

Patent Family Count


U S 2 0 1 8 0 3 4 4 2 2 5

An impedance senor and loop present in

the cup or wearable device makes the

voltage drop due to the oxidation

reaction to measure glucose

concentration.

DexPatent Abstract

Phoenix Silicon Int Corp

2

Portable cup & wearable wristband

for sugar measurement

Innovation Involves

✓ Impedance-detecting apparatus

✓ Voltage drop due to oxidation

reduction reaction

22

By Company

https://worldwide.espacenet.com/publicationDetails/biblio?II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20181206&CC=US&NR=2018344225A1&KC=A1

Patent Family Count


K R 2 0 1 8 0 1 3 1 1 7 8

Blood glucose level is measured by

sampling sugar containing perspiration

secreted by an electrical stimulation

using an electrode

DexPatent Abstract

0

Wearable wrist band

Innovation Involves

23

✓ Wearable wrist band

✓ Blood glucose sensor

✓ Transmitting the glucose values to

server

Kwangwoon University Industry-Academic

Cooperation

By University

Patent Family Count


U S 1 0 1 4 9 6 1 6

Blood glucose of the patient is obtained

using fingertip optical sensor,

transmitted wirelessly.

DexPatent Abstract

7

Wearable wireless device

Innovation Involves

✓ Fingertip optical sensor

✓ Ear clip sensor

✓ Acoustic sensor

24

MASIMO CORP

By Company

https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20181211&DB=&locale=en_EP&CC=US&NR=10149616B2&KC=B2&ND=4

Patent Family Count


H K 1 0 7 1 0 4 4

A system for noninvasive determination

of tissue analytes utilizing the changes

in optical properties of tissue

DexPatent Abstract

SENSYS MEDICAL INC

256

Non-invasive blood glucose

level measuring method

Innovation Involves

✓ Ultraviolet, Visible, mid-IR & NIR

spectroscopy

✓ Changes in optical properties of

tissue

Patent Ceased Due to Non Payment of

Maintenance Fees

25

InactiveBy Company

Legal status

https://worldwide.espacenet.com/publicationDetails/biblio?CC=HK&NR=1071044A1&KC=A1&FT=D&ND=3&date=20100903&DB=&locale=en_EP

Patent Family Count


U S 2 0 1 5 2 8 2 7 6 7

DexPatent Abstract

BODYMEDIA INC

222

Wearable sensor device for

glucose level measurement

Innovation Involves

✓ Wearable sensor

✓ Prediction of glucose level

✓ Two physiological sensor

Abandoned -- Failure to Respond

to an Office Action

26

A system for non-invasively predicting

data related to an individual's glucose

levels by obtaining data from two

physiological sensor.

By Company

Legal status

Inactive

https://worldwide.espacenet.com/publicationDetails/biblio?II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20151008&CC=US&NR=2015282767A1&KC=A1



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Most cited assignees of the published patents

0

50

100

150

200

JPMORGANCHASE BANK

MASIMO SOTERAWIRELESS

CERCACOR HILL ROMSERVICES

Pate

nt

co

un

t

Assignee

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