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TECH, MEET BIO.BIO, MEET TECH.PROGRAM GUIDE The Global Synthetic Biology Summit Mission Bay Conference Center, San Francisco October 1-3, 2018

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2 TECH, MEET BIO. BIO, MEET TECH. The Global Synthetic Biology Summit // Mission Bay Conference Center, San Francisco // October 1-3, 2018 //

Welcome Welcome to SynBioBeta 2018 — our biggest and best event ever. Hundreds of speakers, exhibitors, sponsors and attendees have converged on San Francisco for the main industry event of the year. We are also hosting the first Synthetic Biology Week, a celebration of satellite events throughout the Bay Area. I’d like to thank all of our sponsors, particularly our platinum sponsors Twist Bioscience, Labcyte, Ginkgo Bioworks, and Pivot Bio for making this possible.

This year has brought several fruitful partnerships to SynBioBeta. The strategies outlined in my book “What’s Your Bio Strategy?” have been adopted by a number of leading synthetic biology companies, many of whom are here today. We’ve also partnered with Innovation Lab to compile our strategic market reports and with Silicon Valley Bank for our annual investment report. We hope you enjoy the fruits of these partnerships.

With the economy in overdrive, there has never been a better time to nurture partnerships like these. It’s been another record year for synthetic biology, with a predicted $3B in venture capital funneled into our maturing industry — a signal of biology’s growing importance in our economy. The bioeconomy is reaching into consumer packaged goods, apparel and luxury goods, automotive, chemicals and materials, and more, as a growing number of companies and investors under-stand the importance of biology in their businesses and portfolios.

As the industry grows, it is critical to learn about the latest technology and meet with other entrepreneurs, investors, and thought leaders making biology easier to engineer. SynBioBeta is a place where such discussions are had and partnerships are born — where we can come together to take these endless possibilities and envision how to build a better world for our children, the planet, and beyond. Each and every one of you makes SynBioBeta the experience that it is, and we thank you for your enthusiasm, support, and participation in this amazing community.

The frontier is always in motion as we push ahead, and we are already planning an even bigger event for 2019. We hope we’ll see you again here in San Francisco next October 1-3, 2019.

Regards,

John CumbersCEO and FounderSynBioBeta

SynBioBeta connects people and businesses with ideas and technology.

Sponsors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4-7Exhibitors and Floor Plans Exhibitors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 Main Exhibit Hall Floor Plan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 Robertson Foyer Exhibitor Floor Plan . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Fisher Atrium Floor Plan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17Schedule Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22-24Monday, October 1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30-31Awards . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32-35Tuesday, October 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38-52Wednesday, October 3 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62-732019 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78-95

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Thanks to our Gold Sponsors

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Thanks to our Silver Sponsors

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Thanks to our Bronze Sponsors

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SynBioBeta: the connective tissue for the synthetic biology industry.


By David Kirk. Adapted from the August 29, 2018 SynBioBeta newsletter.

Just as Henry Ford’s assembly line revolutionized the automobile industry, synthetic biology is being revolutionized by automated DNA assembly. The key features of an assembly line translate well into the field of synthetic biology – speed, accuracy, reproducibility and validation. Instead of welding chassis together, small robotic arms are lifting delicate plates holding dozens of samples, adding and removing miniscule amounts of fluid.

In 2014, Imperial College London received £2 million to develop a DNA Synthesis and Construction Foundry to operate with SynbiCITE, the UK Innovation and Knowledge Centre for synthetic biology. Speaking at the Foundry’s inception, SynbiCITE co-director Prof. Paul Freemont said,

“Standardizing the methods for synthesising DNA is crucial if we are going to scale up efforts to design and create this genetic material. The new DNA Synthesis and Construction Foundry will streamline and automate the ‘writing’ of DNA at an industrial scale so that tens of thousands of designed DNA constructions can be built and tested.”

The London DNA Foundry, as it’s now known, represents another major investment from the UK government to boost the synthetic biology industry by addressing global challenges and ultimately providing long term contribution to a sustainable bioeconomy. The Foundry itself has cutting edge automation and analytics technology that addresses the biggest challenge in synthetic biology: how to make high-throughput synthetic DNA constructs and test their specific functions.

Automating Biology“Scientific experimentation in synthetic biology can be reduced to moving tiny bits of liquid from one place to the other” explains Dr. David McClymont, Head of Automation at the Foundry. Once suspended in liquid, DNA can be cut up, stuck together, copied en masse, or mutated. The DNA is then transferred to a microbe like E. coli or yeast to make a library or test the gene product. Organisms “transformed” with this synthetic DNA construct, once in liquid growth culture, can be screened and sub-cultured by the automated platform.

The Assembly Line Of The Future: Automation, DNA Construction, and Synthetic Biology

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As a part of SynbiCITE, the Foundry collaborates with numerous academic and industrial partners to solve high-throughput problems. Creating novel solutions for each individual challenge has added to the Foundry’s expertise in experimental procedure, adopting a four-point engineering approach called ‘Design, build, test, learn’.

Each stage relies heavily on advanced software, integrated into the automated platform. Computer aided design (Bio-CAD) software JMP is used to design experiments. This can interface with the Foundry’s own software, called AMOS, that interfaces with the robots. It also allows users to design and run their own experiments. This software also takes the data retrieved and readies it for analysis and modeling, the “learning” step at the end of the cycle.

Once the project is designed, a multitude of state-of-the-art robots take over. Liquid handling systems including CyBio FeliX and the acoustic-based Echo from Labcyte can deal with 15,000 designs per day. A dizzying array of genetic manipulation techniques can be performed, as well as advanced DNA assembly techniques like BASIC, Golden Gate, and Gibson with subsequent transformation into the microbial chassis of choice.

Once grown in their appropriate experimental conditions, the microbes and their metabolites can be analyzed. The Foundry can monitor their engineered strains at each step in the process from gene expression to protein creation to final product formation, allowing them to identify any bottlenecks in the process.

“Ultimately, unless you solve all these problems, take the whole process apart, and optimize each step of those processes before you put it back together again, it’s not going to work robustly and reliably,” says Dr. McClymont.

Dr. Tom Ellis is one scientist who has successfully used the Foundry to de-bottleneck his high-throughput experiments. He says, “I would say the big bottleneck we have in synthetic biology is screening.” Thousands of DNA constructs can be made in a single pot, but there’s no way to screen for the best one among them by simply picking it out. Automation, and working with the Foundry, has allowed researchers like Dr. Ellis to make those thousands of DNA constructs separately so they can be screened individually.

High throughput analyticsDr. McClymont and Dr. Ellis highlight that, as DNA assembly and strain development speeds up, a new bottleneck appears further down the testing part of the process in detecting target metabolites. Dr. David Bell, formerly of

GSK, leads the Foundry’s analytics department and is developing strategies to increase the throughput.

To detect the compound of interest from the sea of products found in the cell culture, the first step is usually separation. This is typically done by forcing the prepared medium through a special column with liquid or gas, which separates compounds by size in a process called chromatography. The separated compounds can then be detected individually by other methods like UV absorbance, refraction, or mass spectrometry (MS).

The separation step can take quite a long time compared to the relatively quick detection step. Gas chromatography is typically faster than liquid chromatography, but not everything can be separated by gas. Standard setups typically run the separation in the tens-of-minutes to one-hour range, however Dr. Bell has significantly decreased the time required for separation at the Foundry.

“Using a full gradient LC [liquid chromatography] separation, we can run LC/MS assays reliably and robustly with a cycle time of less than 1.5 minutes. We now have the capacity of ten 96-well plates a day for the output of the London DNA Foundry.”

Automation, collaboration and the future of synthetic biologySynbiCITE director Paul Freemont is extremely proud of the Foundry, highlighting that the pharmaceutical background of Drs. McClymont and Bell adds huge value to their partners and projects in terms of design and reproducibility.

The Foundry is open to collaborations with everyone, both in academia and industry. Their highly skilled team have learned by solving numerous novel synthetic biology problems for their partners, and share that with their collaborators.

How does the future look for automated synthetic biology? E. coli remains the workhorse of molecular biology, but with companies like Cell Free Tech removing E. coli from the equation, the assembly lines of the future will make Ferraris rather than Fords.

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Exhibitors Room Booth #Agilent Technologies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .B4Anthropocene Institute . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .211Arbor Biosciences . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .101Aromyx. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .134Arzeda . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .105BASF (Baden Aniline and Soda Factory) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .119Benchling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .126Berkeley Lab . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .124Cambridge Consultants Ltd . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .114 Celemics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .106CLSA (California Life Sciences Association). . . . . . . . . . . . . . . . . . . . . . . . . . . . .215Codexis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .206Conagen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .107Corteva (Dow) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .208Counter Culture Labs. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .132DCVC . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .130DuPont Industrial Biosciences . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .115Elemental Machines. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .121Ecovative . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .125Food Evolution . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .117Genewiz . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .109Gene Universal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .209Genscript . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .B3Gilson Scientific. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .113Ginkgo Bioworks. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .B6Hamilton Robotics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .133Helix Recruiting. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .116IDT-DNA (Integrated DNA Technologies) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .120iGEM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .212Intrexon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .111Labcyte. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .B8Lucigen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .102M2P Labs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .103Mayfield . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .131Mintz Levin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .123

MSU Bioeconomy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .122National Physical Laboratory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .135Novozymes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .137New England Biolabs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .127Opentrons . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .128Oxford Genetics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .138P&G (Procter and Gamble) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .B2Pivot Bio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .B5Riffyn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .207RIL (Reliance Industries Limited) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .112Singer Instruments. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .108Spruce Capital Partners. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .129SynbiCITE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140 & 141Synbio Tech . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .118Synthego . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .104Teknova . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .110TeselaGen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .213Thermo Fisher. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .B7 Twist Bioscience . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .B1Zymergen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .210

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Come join us and build a better world with biology.

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Schedule Overview - Monday, October 15pm 5:00pm -

Registration and kick-off party (SynBioBeta and Synthetic Biology Week)(Sponsored by Labcyte)

6pm 6:00pm - Welcome

6:05pm -Keynote panel: Built with biology: A revolution in materials (Wallach, Drechsler, Bayer)

6:25pm -Panel: Educate, incubate, accelerate

6:55pm -SynBioBeta awards

7pm 7:10pm -Fireside chat: DIY bio: The home brew computer club (Church, Gentry, Wozniak)

8pm 8:10pm -Wrap-up

8:00pm -Kick-off party continues (sponsored by Labcyte)

9pm

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Schedule Overview - Tuesday, October 2 7am 7:30am - Registration 7:30am - Breakfast (sponsored by

Thermo Fisher Scientific)7:30am - Breakfast (sponsored by Mintz Levin)

7:30am - Breakfast (sponsored by Tech•Bio)

8am 8:30am - Welcome

8:35am - Keynote fireside chat: Neuroscience + synthetic biology: The neobiological revolution ( Johnson, Boyden, Metcalfe)

9am 9:05am - Fireside chat: A conversation with Twist Bioscience (Leproust, Brown)

9:25am - Session talks: Why protein is (still) the killer app (sponsored by Codexis)

10am 10:10am - Featured spotlight, Labcyte

10:15am - Coffee break and workshops 10:15am - Workshop: Cost-efficient DNA construction and sequencing using acoustic liquid handling (sponsored by Labcyte) (Breakout room R2)

10:20am - Focus panel: Emerging women leaders in synthetic biology (sponsored by Ginkgo Bioworks) (Breakout room R1)

10:20am - Focus panel: Future literacy & investing in hard tech science (Breakout room R3)

11am 11:00am - Panel: Emerging security issues for the bioeconomy (sponsored by the Open Philanthropy Project)

11:35am - Session talks: Living medicines, and engineering the microbiome (sponsored by Ginkgo Bioworks)

12pm 12:20pm - Lunch (sponsored by Ginkgo Bioworks)

12:30pm - Lunch and learn: Advances in DNA synthesis (sponsored by Thermo Fisher) (Breakout room R1)

12:30pm - Lunch and learn: Affordable, open-source lab automation (sponsored by Opentrons) (Breakout room R2)

12:30pm - Lunch and learn: DNA data storage: Quo vadis? (sponsored by SemiSynBio) (Breakout room R3)

12:30pm - Picnic lunch and learn: Beer brewing and synthetic biology: The Sleight Beer Lab (sponsored by Sleight Beer Labs) (Picnic 1)

12:30pm - Picnic lunch and learn: Women founders’ mentoring lunch and learn (sponsored by Ginkgo Bioworks) (Picnic 2)

1pm 1:40pm - Lightning talks, 1 (sponsored by Novozymes) (Main stage)

1:40pm - Focus breakout session: Biopharma and healthcare (sponsored by Oxford Genetics) (Breakout room R1)

1:40pm - Focus breakout session: Environmental applications of synthetic biology (Breakout room R2)

1:40pm - Focus panel: Food and beverage: What’s your bio strategy? (Breakout room R3)

2pm 2:25pm - Break

2:30pm - Panel: Bio is not another app: Investing in what’s important (Main stage)

2:30pm - Focus breakout sesssion: Measuring what matters (Breakout room R1)

2:30pm - Focus breakout session: Democratizing the hardware stack (Breakout room R2)

2:30pm - Focus panel: Pharma, biotech, and healthcare: What’s your bio strategy? (Breakout room R3)

3pm 3:15pm - Break

3:20pm - Session: Engineered celltherapies (sponsored by Synthego) (Main stage)

3:20pm - Focus breakout session: Space applications of synthetic biology (Breakout room R1)

3:20pm - Focus breakout session: Scaling up for food, biomaterials and consumer goods (Breakout room R2)

3:20pm - Focus panel: The global picture: Synthetic biology in China, France, and beyond (Breakout room R3)

4pm 4:05pm - Featured spotlight: What can’t you do with algae? (Reliance Industries Limited)

4:10pm - Coffee break and workshops 4:10pm - Workshop: Codexis protein innovations: Impacting real world mar-kets, rapidly (sponsored by Codexis) (Breakout room R1)

4:10pm - Workshop: Pitch your ideas around the world with BASF (sponsored by BASF) (Breakout room R2)

4:10pm - Workshop: Game-changing DNA construct design (sponsored by GenScript) (Breakout room R3)

4:55pm - Session: The lab of the future (Main stage)

4:55pm - Workshop: “America’s Seed Fund”: Using NSF SBIR to transform your technology into commercial success (sponsored by NSF) (Breakout room R1)

4:55pm - Focus breakout session: Cyanobacteria, algal engineering & the ocean of life (sponsored by Reliance Industries Limited) (Breakout room R2)

4:55pm - Focus breakout session: Scaling-up partnerships for food, flavor, and fragrances (sponsored by Conagen) (Breakout room R3)

5pm 5:50pm - Featured spotlight: Next Steps for the Biofabrication Revolution (Ecovative)

5:55pm - Wrap-up

7pm 7:30pm - P&G afterparty at IndieBio

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Schedule Overview - Wednesday, October 3 7am 7:30am - Registration 7:30am - Breakfast, coffee and pastries

8am 8:30am - Welcome (Main stage)

8:40am - Keynote: Twenty years of synthetic biology: How far are we from 1998? (Gardner)

9am 9:00am - Session: DNA data storage (sponsored by SemiSynBio) (Main stage)

9:30am - Session talks: Advanced molecular manufacturing, chemicals, and materials (sponsored by Ecovative)

10am 10:15am - Coffee break

10:45am - Session talks: Food 2.0

11am 11:30am - Fireside chat: Agriculture’s pivot toward sustaining water, air and oceans (Temme, Degnarain)

11:50 am - Keynote panel: Go big or go home: Scaling up the biofab (Kelly, Schilling)

12pm 12:15pm - Lunch (sponsored by Twist Bioscience)

12:20pm - Focus breakout session: Massively parallel systematic discovery in cell-free synthetic biology (sponsored by Arbor Biosciences) (Breakout room R1)

12:20pm - Workshop: Lab data to machine learning in 30 seconds (sponsored by Riffyn) (Breakout room R2)

12:20pm - Lunch and learn: Building synthetic biology companies that scale (sponsored by Mayfield / WSGR) (Breakout room R3)

12:20pm - Picnic lunch and learn: Regulation and oversight of synthetic biology (Science Policy Consulting LLC) (Picnic 1)

1pm 1:25pm - Lightning talks, 2 (Main stage)

1:25pm - Focus panel: Decentralization of Technology and Scale: What’s Your Bio Strategy? (Breakout room R1)

1:25pm - Focus breakout session: Biosecurity by design: traceability & bio with blockchain (Breakout room R2)

1:25pm - Focus breakout session: Engineered cancer immunotherapies (sponsored by Distributed Bio) (Breakout room R3)

2pm 2:10pm - Break

2:15pm - Session talks: New tools of the trade: Cell-free synthetic biology, engineered enzymes, and antibodies (Main stage)

2:15pm - Focus panel: Chemicals and materials: What’s your bio strategy? (Breakout room R1)

2:15pm - Focus breakout session: Design and synthetic biology (Breakout room R2)

2:15pm - Focus breakout session: Science fiction and synthetic biology (Breakout room R3)

3pm 3:00pm - Break

3:05pm - Panel: Genetic literacy (Main stage)

3:05pm - Focus panel: Companies that change the rules of the game (sponsored by Civilization Ventures) (Breakout room R1)

3:05pm - Focus panel: Consumer packaged goods: What’s your bio strategy? (Breakout room R2)

3:05pm - Focus breakout session: Biodiversity and synthetic biology (Breakout room R3)

3:50pm - Featured spotlight, Mother Dirt

3:55pm - Coffee break and workshops

3:55pm - Workshop: Partnering opportunities with Procter & Gamble (sponsored by Procter & Gamble) (Breakout room R1)

3:55pm - Workshop: The future of farming (sponsored by Pivot Bio) (Breakout room R2)

3:55pm - Workshop: A New Approach to Classifying Industrial Microorganisms – moving the discussion beyond ‘Natural’ vs GMO (sponsored by DuPont) (Breakout room R3)

4pm 4:40pm - Fireside chat: Why aren’t there more scientists in politics? (Eisen, Duncan)

6pm 5:00pm - Keynote panel: Automation and machine learning: The impact on biopharma (Aatresh, Fischer-Colbrie, Baldoni)

5:20pm - Panel: The future of DNA synthesis (sponsored by Molecular Assemblies)

6pm 6:00pm - Wrap-up

7pm 7:30pm - SynBioBeta afterparty at The AWS Loft

Visit Opentrons.com

A special thank you to Ecovative for bringing you the Mushroom Stage at SynBioBeta 2018!

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6:00pm - MAIN STAGE Welcome____

John Cumbers welcomes you to SynBioBeta 2018 and kicks off Synthetic Biology Week. He’ll share some highlights from the conference to come, share some exciting news, and give you a sneak preview of what’s in store for 2019.

speaker: John Cumbers, SynBioBeta

5:00pm - ATRIUM Registration and kick-off party (sponsored by Labcyte)____

Upon registering, we’d like to include you in becoming a part of our dedicated group of innovators, creators, and dreamers who are building a better world with biology.

6:05pm - MAIN STAGE Keynote panel: Built with biology: A revolution in materials____

Our ability to engineer biology at the molecular level makes it possible to create sustainable replacement materials and new higher-performance materials like never before. Join this opening discussion on the new era of truly green industrialization and how it is impacting plastics, packaging, fabrics, and more.

speakers: Lee Ellen Drechsler, P&G; Eben Bayer, Ecovative

moderator: D.A. Wallach, Inevitable Ventures

6:25pm - MAIN STAGE Panel: Educate, incubate, accelerate____

We’re training a new cadre of synthetic biologists who will be the engine of the bioeconomy. On this panel, we will hear from educators, incubators, and accelerators about how this generation of researchers is not only transforming the existing bioeconomy, but also how it engages with our customers, the public, and each other about building the future with biology.

speakers: Stephanie Marrus, UCSF; Johannes Fruehauf, LabCentral; Richard Kitney, SynbiCITE; Nicholas Toriello, Novozymes

moderator: John Cumbers, SynBioBeta

Schedule Details - Monday, October 1

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7:10pm - 8:10pmMAIN STAGE Fireside chat: DIY bio: The home brew computer club____

This epic meeting of titans will be moderated by the co-founder of BioCurious, Eri Gentry. This is a rare opportunity to bring together two giants of technology who are responsible for creating so much innovation in the world. Wozniak and Church have had such a big impact on humanity and have been at the forefront of their respective fields for so many years. This conversation is the epitome of Tech Meets Bio, Bio Meets Tech, our theme for SynBioBeta 2018.

speakers: Steve Wozniak, Technology Entrepreneur; George Church, Harvard and MIT

moderator: Eri Gentry, BioCurious

6:55pm - MAIN STAGE SynBioBeta Awards____

Each year, SynBioBeta recognizes and celebrates pioneers within our community for their spirit and passion in making the universe a better place with biology. This year, Rob Carlson of Bioeconomy Capital presents the Engineering Biology Awards to our honored recipients.

award winners: Dr. Christina Agapakis, Gingko Bioworks EXCELLENCE IN PUBLIC ENGAGEMENT

OS FundLEADERSHIP IN SYNTHETIC BIOLOGYBryan Johnson and Jeffrey Klunzinger

SynbiCITELEADERSHIP IN SYNTHETIC BIOLOGY Dr. Richard Kitney and Dr. Paul Fremont

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The 4th Annual Engineering Biology Awards Recognize Excellence in the Synthetic Biology Industry at SynBioBeta SF 2018!

SynBioBeta is proud to acknowledge women and men who have made great strides to shape the synthetic biology landscape. In 2014, we created the Engineering Biology Awards as a way to highlight the great science, engineering, and technologies being pioneered within our community. Previous award winners have included many of the pioneers of synthetic biology: Dan Gibson, Drew Endy, Alicia Jackson, Christina Smolke, Christopher Voigt and Rt. Hon. Lord David Willets. This year, SynBioBeta invites you to join us in recognizing five tremendous contributors to our field.

Dr. Christina Agapakis, Gingko Bioworksexcellence in public engagementDr. Agapakis has played a critical role in engaging the public with synthetic biology through her numerous written works, including several guest pieces for SynBioBeta. She is also founding editor of the science magazine Method Quarterly. Her PhD work at Harvard Medical School focused on hydrogen-fuel producing bacteria, and she is also known for making cheese using bacteria collected from the human body. Dr. Agapakis is also an artist, and has taught designers at the Art Center College of Design as well as biomolecular engineers at UCLA.

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Bryan Johnson, OS Fundleadership in synthetic biologyThrough the OS Fund, Johnson has invested in a number of early stage science and technology companies working to benefit humanity through discoveries on the operating system (OS) level. His vision is to take companies “from crazy to viable,” tackling some of the world’s most fundamental issues that can be solved by synthetic biology. He has also founded Braintree, which facilitates mobile and web payments for e-commerce, and Kernel, which aims to build an implantable device that can be used to improve brain function.

Jeffrey Klunzinger, OS Fundleadership in synthetic biologyThrough the OS fund, Klunzinger is enabling the next generation of entrepreneurs focused on realizing advancements that are fundamental to our future. A certified public accountant, Klunzinger brings 20 years of investment experience to the OS Fund. He began his career at Ernst and Young, and later co-founded and served as CFO of West Family Investments.

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The 4th Annual Engineering Biology Awards Recognize Excellence in the Synthetic Biology Industry at SynBioBeta SF 2018!

Dr. Paul Fremont, SynbiCITEleadership in synthetic biologySynbiCITE is the Innovation and Knowledge Centre of Imperial College’s Hub for Synthetic Biology, and aims to bridge the gap between academia and industry to speed up synthetic biology discoveries and applications. Dr. Fremont has played a key part in the development of synthetic biology in the UK and was a co-author of the British Government’s UK Synthetic Biology Roadmap. He has also participated as a technical expert in the United Nations Convention for Biological Diversity and Biological Weapons Convention and is a working group member of the US NIST synthetic biology standards consortium.

Dr. Richard Kitney, SynbiCITEleadership in synthetic biologyA well-respected synthetic biology researcher, he helped develop the Imperial College Hub for Synthetic Biology, of which SynbiCITE is a part. Through his efforts, he is helping to make synthetic biology a core part of the UK economy, and is helping to drive fundamental breakthroughs in the industry. At Imperial College, Dr. Kitneywas Founding Head of the Department of Bioengineering, Dean of the Faculty of Engineering. He is also Chairman of the Institute of Systems and Synthetic Biology, Co-Director of the EPSRC National Centre for Synthetic Biology and Innovation.

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8:35am -MAIN STAGE

Keynote fireside chat: Neuroscience & synthetic biology: The neobiological revolution____

Two decades of breakthroughs in neuroscience and synthetic biolo-gy are merging, giving rise to new technologies that can potentially treat neurological diseases and even enhance cognitive abilities. What does this Neobiological Revolution have in store for us as individuals and as a society? Join a conversation among visionaries and luminaries on the future of the brain.

speakers: Bryan Johnson, OS Fund and Braintree; Ed Boyden, MIT Media Lab and the MIT McGovern Institute; Jane Metcalfe, NEO.LIFE

9:05am -MAIN STAGE

Fireside chat: A conversation with Twist Bioscience____

Emily Leproust is a pioneer of high-throughput synthesis and sequencing of DNA. As CEO of Twist Biocience, she continues to push the envelope and disrupt the fields of medicine, DNA data storage, agricultural biology, and industrial chemicals. Here, Emily shares with the SynBioBeta community her view on the trends, technologies, and people shaping the future of the bioeconomy.

speakers: Emily Leproust, Twist Bioscience; Kristen Brown, Bloomberg

7:30am -Registration and breakfast ____

ATRIUMSponsored by Thermo Fisher ScientificBREAKOUT ROOM R1Sponsored by Mintz LevinBREAKOUT ROOM R3Sponsored by Tech•Bio

8:30am - MAIN STAGE Welcome____

Kicking off day 2 of SynBioBeta 2018 with enthusiastic talks and introductions.

speakers: John Cumbers, SynBioBeta; Brandon Clark

Schedule Details - Tuesday, October 2

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10:15am - Coffee break and workshops____

Take a break and check out the exhibit hall, where you can make valuable connections and learn about the latest synthetic biology technologies. Workshops will also be running during the break.

9:25am - MAIN STAGE

Session talks: Why protein is (still) the killer app (sponsored by Codexis)____

DNA has gotten lots of attention, but almost everything in biotech relies on what DNA makes: proteins. In this session, we will hear about the latest tools and technologies in protein engineering, with recent examples of novel proteins with extraordinary functions.

speakers: John Nicols, Codexis; Michael Mendez, Renew BioPharma; Sarah Ives, Distributed Bio; Alexandre Zanghellini, Arzeda

moderator: Christine Gould, Thought for Food

10:10am - MAIN STAGE

Featured spotlight, Labcyte____

speaker: Mark Fischer-Colbrie, Labcyte

10:15am - BREAKOUT ROOM R2

Workshop: Cost-efficient DNA construction and sequencing using acoustic liquid handling (sponsored by Labcyte)____

Want to build more strains AND reduce your consumables? Come to this workshop and learn about how to build a faster, cheaper, and more eco-friendly automation pipeline using the Labcyte Echo Liquid Handler, a lab automation platform that uses acoustic energy to perform precision, non-contact liquid handling.

speakers: Jared Bailey, Labycte; Jefferson Lai, Labycte


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11:00am -MAIN STAGE

Panel: Emerging security issues for the bioeconomy (sponsored by the Open Philanthropy Project)____

In an increasingly interconnected and biotechnology-enabled world, biosafety and biosecurity monitoring should become proactive and seamless. How do we manage biosecurity at both a local and a global level? What new risks have emerged from the development of synthetic biology? How can the synthetic biology community get progressively more involved in public policy? We are bringing together pioneers and experts from diverse backgrounds to explore these questions.

speakers: Megan Palmer, Center for International Security and Cooperation; Peter Carr, MIT Lincoln Laboratory; Ryan Ritterson, Gryphon Scientific; James Diggans, Twist Bioscience

moderator: Gigi Gronvall, Johns Hopkins Center for Health Security

11:35am -MAIN STAGE

Session talks: Living medicines, and engineering the microbiome (sponsored by Ginkgo Bioworks) ____

In the past decade, the human microbiome has garnered an in-credible amount of traction as a research subject and space for health intervention. This is an exciting area of growth and innovation. In this session, we will hear from companies engineering microbes for impactful applications: probiotics, next-gener-ation personal care products, oral vaccines, immunotherapies, and skin disease treatments.

speakers: Ena Cratsenburg, Ginkgo Bioworks; Ted Fjallman, Prokarium; Travis Whitfill, Azitra; David Kyle, Evolve BioSystems; Paul Garofolo, Locus Bio



Focus panel: Future literacy & investing in hard tech science____

As synthetic biology accelerates our ability to design nature itself, how do we know if we’re prepared? Have we set the right goals, and do we know how to get to them? Bryan Johnson leads a frank discussion about how and whether the synthetic biology community is future-proofing itself against the potential negative consequences of our biggest skeptics. This session considers how synthetic biologists can begin future-proofing their research, their business, and themselves.

speakers: Bryan Johnson, Kernel, OS Fund and Braintree; John Cumbers, SynBioBeta



Focus panel: Emerging womenleaders in synthetic biology(sponsored by Ginkgo Bioworks)____

The underrepresentation of women in science and engineering careers persists in both academia and indus-try, despite growing awareness of the problem and the recognition of diversity as a business value. Have the challenges for women scientists decreased much in the last ten years? Is the #METOO movement equally reflective of Silicon Valley and science? How do we identify/create/amplify/become champions and mentors at the highest levels? Our panel of founders and mentors will take up these and other questions.

speakers: Kat Manalac, Y Combinator; Maria Orozco, NFX; Marilene Pavan, Boston University; Christina Agapakis, Ginkgo Bioworks; Meagan Lizarazo, EM

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12:30pm - BREAKOUT ROOM R2

Lunch and learn: Affordable, open-source lab automation (sponsored by Opentrons)____

In this hands-on session, Opentrons’ Kristin Ellis gives attendees an opportunity to interact with the Opentrons OT-2, an affordable, open-source liquid handling robot poised to make lab automation accessible to everyone. Come learn how easy it is to program a desktop robot to do more in less time in your lab.

speaker: Kristin Ellis, Opentrons

12:20pm - Lunch (sponsored by Ginkgo Bioworks)___

Grab a bite and hit the exhibit hall to meet with many of the leading innovators, thinkers, and investors in our community.


12:30pm -BREAKOUT ROOM R3

Lunch and learn: DNA data storage: Quo vadis? (sponsored by SemiSynBio)____

If we stored all the world’s data in flash memory, we would run out of the raw materials in 25 years, yet all the world’s data could theoretically be stored in a teaspoonful of DNA material. Our panelists share the latest breakthroughs in DNA data storage, and share a vision for how DNA could become your failsafe, lossless backup.

speaker: Victor Zhirnov, Semiconductor Research Consortium


Lunch and learn: Advances in DNA synthesis (sponsored by Thermo Fisher)____

Learn about how Thermo Fisher Scientific’s innovative DNA synthesis technology allows customers to make the world a healthier, cleaner and safer place.

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1:40pm -MAIN STAGE

Lightning talks, 1 (sponsored byNovozymes)____

Get a panoramic overview of the cutting edge landscape of synthetic biology in this rapid session of four-minute talks with scientific leaders, innovators of the bioeco-nomy, and the best and brightest newcomers.

speakers: Zack Abbott, Zbiotics; Hugh Goold, Macquerie University; Thomas Ybert, DNA Script; Vince Sewalt, Dupont; Nikole Kimes, Siolta Therapeutics; Omri Amirav, Drory; Arvind Gupta, Indie Bio; Ursheet Parikh, Mayfield Fund; Adam Clore, IDT; Nicholas Toriello, Novozymes


12:30pm -PICNIC 2 ON THE LAWN

Lunch and learn: Women founders’ mentoring lunch and learn (sponsored by Ginkgo Bioworks)____

Join Ginkgo Bioworks Creative Director Christina Agapakis for an interactive lunch and learn session on being a woman in the synthetic biology industry. Learn from Christina’s own personal experiences how to overcome challenges, reap rewards, and survive - and even thrive - in a field that still suffers from gender inequality.

speaker: Christina Agapakis, Gingko Bioworks


Focus breakout session: Biopharma and healthcare (sponsored by Oxford Genetics)____

We are entering a new era of medicine – one that works with biology, not against it. Engineered biomolecules are hitting ‘undruggable’ targets, the immune system is being programmed to fight cancer, and the microbes within us are being har-nessed to improve health. These are other clinical breakthroughs are the result of engineered biology. This series of talks will show how synbio has become the cutting edge in pharma and healthcare.

speakers: Maria Soloveychik, SyntheX; David Younger, A-Alpha Bio; Drew Titmarsh, Scaled Biolabs; Melanie Matheu, Prellis Biologics; Wenning Qin, eGenesis

moderator: Ryan Cawood, Oxford Genetics


12:30pm -PICNIC 1 ON THE LAWN

Picnic lunch and learn: Beer brewing and synthetic biology: The Sleight Beer Lab (sponsored by Sleight)____

In this picnic workshop, Sean Sleight will discuss the beer brewing process, how it compares to industrial fermentation, and share examples of current and future synthetic biology applications to brew better beer. He will discuss genetic control of yeast flocculation, and engineered yeast strains to make beer that tastes like banana and citrusy-smelling valencene. Samples will be served.

speakers: Sean Sleight, Sleight; Karl Handelsman, Sleight

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Focus breakout session: Environmental applications of synthetic biology____

Synthetic biology offers powerful tools for protecting the environment, from reducing harmful emissions to neutralizing toxic by-products to increasing biodiversity. Join this session to learn about the latest applications, and how your technology may be able to help turn the tide.

speakers: Peter Meinhold, Provivi; Fatma Kaplan, Pheronym; Dominique Waddoup, BirdShades

moderator: Keira Havens, Pivot Bio


Focus panel: Food and beverage: What’s your bio strategy?____

As the global food supply is increas-ingly strained, synthetic biology will play an increasing role in making foods with better nutrition and flavor. These efforts are not only potentially profitable, but less environmentally harmful than conventional production methods. This focus session explores these themes with a vanguard of food and beverage industry experts.

speaker: Ravindra Rathi, PepsiCo R&D

moderator: Simone Ross, Consultant

2:25pm -Break____

Take a break and check out the exhibit hall, where you can make valuable connections and learn about the latest synthetic biology technologies.


2:30pm - MAIN STAGE

Panel: Bio is not another app: Investing in what’s important____

“Biotech is not another app. This is not an e-commerce play that may go for a year or two and die out. These are things that are actually going to affect our lives, for all of us.” –Sean O’Sullivan

Is purpose increasingly shaping scientific and tech development? Is impact investing part of the society trend of realigning business priorities? Join our synthetic biology investor panel in exploring the rapidly evolv-ing landscape of investing in things that are truly important.

speakers: Seth Bannon, Fifty Years; Annie Hazlehurst, Faridan; Alaa Halawa, Mubadala; Ganesh Kishore, Spruce Capital; Kiersten Stead, DCVC

moderator: Navjot Singh, McKinsey & Company

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3:15pm -Break____



Focus breakout session: Democratizing biotech through affordable, open-source stacks____

Will affordable, open-source biotech enable small players to push the envelope of synthetic biology? How can low-cost hardware contribute to the decentralization of innovation in biology? Is the demand for low-cost hardware creating new markets for the existing industry? We bring together a panel of experts to explore these questions.

speakers: Josh Perfetto, Chai; Federico Muffatto, Digi.Bio; Alexander Murer, Briefcase Biotec; Gilad Gomé, Media Innovation Lab (miLAB)

moderator: Bethan Wolfenden, Bento Bio


Focus panel: Pharma, biotech, and healthcare: What’s your bio strategy?____

Synthetic biology is reimagining pharma, with investment rising from half a billion dollars three years ago to a projected $2.4 billion in 2018. A few companies are leading the way, building bridges from their historical discovery and manufacturing approaches to increasingly apply cutting-edge synthetic biology tools. Comelearn how these forward-thinking companies are developing bio strategies within the biotech sector itself.

speakers: Parijat Bhatangar, SRI International; Ronald Niland, Gilead Sciences; Melissa Thomas, Biologics - Protein Technologies; Beth Hill, J&J Innovation

moderator: Sandor Schoichet, Meridian Management Consultants



Focus breakout session: Measuring what matters____

What role will measurement tech-nology play in the development of our field? What precision tools do we lack in order to get to the next stage of capability? What is the state of the art, and where do we want to be in 2025? Join this session to explore answers to these and other questions.

speakers: Dennis Eastburn, MissionBio; Jacob Beal, BBN Technologies; Marc Salit, Stanford; Keoni Gandall, Biohacker

moderator: Jacob Beal, BBN Technologies

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Focus breakout session: Space applications of synthetic biology____

Here on Earth, evolution has optimized biological systems for life on a blue planet. If we are to venture into space, biology will have to be engineered for extraterrestrial conditions. What can we learn from biological efficiency? How can biofabrication be adapted to extraterrestrial conditions? Our panelists launch into these questions.

speakers: Amy Chen, University of Calgary; Lynn Rothschild, NASA; Briardo Llorente, Macquerie University; Rocco Mancinelli, Bay Area Environmental Research Institute

moderator: Miki Sode, Briardo Llorente


Focus breakout session: Scaling up for food, biomaterials, and consumer goods____

Bio-based manufacturing processes must be not only be as cheap as their decades-old conventional cousins, but they must also prove equal performance. How best is synthetic biology used to de-risk the scale-up process, and how can startups posi-tion their technology for maximum scalability?

speakers: Deepak Dugar, Visolis; John Evans, AB Mauri North America; Sarah Milsom, Touchlight Genetics; Francia Navarrete Utreras, Protera Biosciences; Martin Plambech, Biosyntia

moderator: Deepak Dugar, Visolis


Focus panel: The global picture: Synthetic biology in China, France, and beyond____

China has taken an aggressive approach to becoming the world leader in synthetic biology. France has taken a more decentralized and diversified approach. Come learn how the socio-political environment of these and other countries ramifies the trajectory of the field and gives rise to particular innovations and partnership opportunities around the world.

speakers: Greg Scott, ChinaBio; Li Teng, Tsinghua University; Estella Ho, Shanghai Tech University; Pierre Monsan, INRA-TWB

moderator: John Hugh Snyder, Manuscript Revisions


3:20pm -MAIN STAGE

Session: Engineered cell therapies (sponsored by Synthego)____

First-generation cell therapies are already in the clinic battling previously incurable diseases, but safety concerns may hamper their adoption. Can synthetic biology provide the control and precision needed to achieve widespread success? See the new frontier of therapeutics in universal vaccine design, antibody engineering, and gene/cell therapy with trailblazers in the synthetic biology community.

speakers: Alec Nielsen, Asimov; Helge Bastian, Thermo Fisher Scientific; Ryan Cawood, Oxford Genetics; Kevin Holden, Synthego


A special thank you to Pivot Bio for bringing the digital lounge LED experience to SynBioBeta 2018!

led wall sponsored by

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4:10pm -Coffee break and workshops____

Take a break and check out the exhibit hall, where you can make valuable connections and learn about the latest synthetic biology technologies. Workshops will also be running during the breaks.


Workshop: Enzyme Cascade Synthesis – Leading Today’s BioIndustrial Revolution (sponsored by Codexis)____

Learn how the engineering of novel Enzyme Cascades is increasingly winning in the competition for low cost, sustainable complex chemistry route design. Often referred to as ‘in vitro’ or ‘isolated enzymatic’ routes, Enzyme Cascade bioindustrial route design is proving faster to market, with inherent cost and sustainability benefits versus engineered microorganism-driven (or, whole cell) fermentation approaches. See success case studies in food, diagnostic and pharmaceutical industries.

speakers: John Nicols, Codexis; Jim LeLonde, Codexis


Workshop: Pitch your ideas around the world with BASF (sponsored by BASF)____

Through science and innovation, we enable our customers in nearly every industry to meet the current and future needs of society. Join us and share your top ideas with our repre-sentatives from Scouting, Innovation, and Bioscience. We can connect your thoughts to our global organization and discuss how we might be able to work together.

speaker: Jens Plassmeier, BASF


4:05pm - MAIN STAGE

Featured spotlight: What can’t you do with algae? (Reliance Industries Limited)____

speaker: Ajit Sapre, Reliance Industries Limited

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Workshop: Game-changing DNA construct design (sponsored by GenScript)____

Is plasmid design giving you difficulty? Are you looking to share your work with the global scientific community? We provide free design and communication tools to support open science and collaboration. Come learn with the GenSmartTM Design Tool and MolecularCloudTM Plasmid Repository.

speaker: Yuki Qin, Genscript


Focus breakout session: Cyanobacteria, algal engineering & ocean of life (sponsored by Reliance Industries Limited)____

This session will dive into the oceans of life and understand the potentials for engineering photosynthetic organisms, the power of synthetic biology to provide sustainable solutions to environmental problems such as ocean acidification, dead zones, and the ability to restore natural wetland climates.

speakers: Tariq Warsi, Catalina Sea Ranch; Santanu Dasgupta, Reliance; Miller Tran, Tritonai; Robert Brown, Synthetic Genomics

moderator: Gautam Das, Reliance


4:55pm - BREAKOUT ROOM R1Workshop: “America’s Seed Fund”: Using NSF SBIR to transform your technology into commercial success (sponsored by NSF)____

NSF’s SBIR progam has been “America’s Seed Fund” for 40 years, helping startups and small businesses transform their ideas into marketable products and services. Join NSF and like-minded entrepreneurs for a workshop on turning high-risk, high-impact technologies into validated products and economic success stories.

speaker: Ruth Shuman, NSF

4:55pm -MAIN STAGE

Session: The lab of the future____

The lab is getting smarter, cheaper, and more agile. In this session, we take a look at the latest and greatest in laboratory innovation, from the Internet of Things to the “PC moment” in lab automation, and ask the innovators who are radically changing how we work at the bench and explore how lab managers can take full advantage of these technologies to meet their continu-ous improvement goals and expand their strategic impact, all while taking on more complex challenges.

speakers: Will Canine, Opentrons; Sridhar Iyengar, Elemental Machines; Ali Afshar, Cytera CellWorks; Melanie Adams, TTP Labtech


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5:50pm - MAIN STAGE

Featured spotlight: Next Steps for the Biofabrication Revolution (Ecovative)____

speaker: Eben Bayer, Ecovative



Focus breakout session: Scaling-up partnerships for food, flavor, and fragrances (sponsored by Conagen)____

Bio-based manufacturing processes must not only be as cheap as their decades-old conventional cousins, but they must also prove equal performance. How best is synthetic biology used to de-risk the scale-up process, and how can startups position their technology for maximum scalability?

speakers: Matthew Mattozzi, Conagen; Oliver Yu, Conagen; Ross Zirkle, DSM Nutritional Products; Harshal Kshirsagar, Clara Foods; Perumal Gandhi, Perfect Day

The Future is in Our DNA

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Synthetic biology: technologies to build a better and more sustainable universe.

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By Embriette Hyde. Adapted from the July 15, 2018 SynBioBeta newsletter.

I try not to laugh as Dr. Armpit carefully swipes — and tickles — my armpit with a large swab. I am a participant in his latest study to determine the factors that affect the microbes living on our skin — and how those microbes contribute to our body odor. Dr. Armpit is very clear: body odor is not a disease, it’s a problem with your microbiome.

The gut microbiome has become a red hot topic in the last several years, and applications like probiotics and fecal microbial transplants have garnered much attention. But many people are less aware of how important a healthy microbiome is for your skin. Research groups across academia and industry are fervently studying how to leverage skin microbes to improve skin health. Armpit odor is just one example of how skin microbes can go haywire, and we’ll return to Dr. Armpit in a moment. But let’s first take look at how microbial engineering can help with one of the most prevalent skin disorders: eczema.

Worldwide, about 10 percent of adults have some form of eczema, and it’s even more prevalent among children. If you or someone you know suffers from eczema, you know how challenging it can be. Scratchy, red skin that cracks and bleeds is not only painful, but can also leave you homebound, embarrassed to show your scarlet splotches in public. Hand and body lotions may offer some relief, while pharmaceuticals are pricey and come with an entourage of side effects.

Skin is the largest organ of the human body, and is critical as a first line of defense against pathogens, the sun, wind, and water. Its function is crucial for human health, and it often holds important clues about our health. Skin breakouts can be a sign of a poor diet, food or environmental allergy, or early signs of an autoimmune disease. Blemishes can signal sun damage or cancer. We admire those whose skin “glows with health” and do anything we can to avoid wrinkles as we age. We feel sorry for those whose skin is ravaged by eczema. And, some skin diseases, such as Netherton Syndrome in infants, can be fatal or have life-long health consequences. Billions are poured into

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the cosmetics and skin pharmaceutical industries each year as we try to optimize the health of this critical organ.

As we consider the health of our skin, we must take into account the thousands of microbes that call our skin home. These microscopic live-ins eat sweat and give us each our own body odor, attract or repel mosquitos (yes, mosquitos do prefer you to your brother on camping trips), and, most importantly, help keep our skin healthy. For example, Staphylococcus epidermidis helps promote wound healing by inhibiting inflammation and can protect against potential skin pathogens, such as Staphylococcus aureus. It has also been shown to help with moisture retention when applied topically. But it is likely too simplistic to view individual skin microbes as either good or bad. In most cases, the community as an entire ecosystem is the critical component for the well-being of our skin.

More diverse microbial communities — those with a variety of species that contribute a wide array of metabolic functions — are associated with healthier skin. Conversely, unbalanced, or dysbiotic, microbial communities are observed in several skin conditions including acne and eczema, where Propi-onibacterium acnes and S. aureus, respectively, comprise abnormally large proportions of the skin microbial community.

Chris Callewaert, known in the microbiome research community as “Dr. Armpit,” is one of the most active researchers seeking to apply skin microbes in practical ways. As a postdoctoral researcher at Ghent University in Belgium and the University of California, San Diego, Dr. Callewaert is partic-ularly interested in tackling embarrassing body odor through skin microbiome

“transplants.” He admits that body odor is not a disease, but emphasizes the psychological impacts it can have, especially on women, who, according to his research, tend to smell better than men but feel more ashamed about their body odor than men.

“We found a way to temporarily solve body odor by means of an underarm bacterial transplant from a family member that does not have body odor,” he tells me. “Treatments on 17 subjects showed that we could shift the underarm microbiome to a better smelling one, which was coupled to a significant improvement in underarm odor, for up to one month.” And Dr. Armpit is not the only one interested in solving the problem of body odor through microbes. There are some microbiome-based commercial products already on the mar-ket that claim to reduce body odor and clear up acne and other conditions by

re-introducing microbes that purportedly have been eliminated by modern hygiene practices, though many are skeptical, claiming that the supporting science doesn’t yet exist.

Others are focused on more clinically relevant applications. Richard Gallo and his UC San Diego laboratory team recently reported the successful design of a personalized probiotic skin cream to relieve the most common form of eczema, atopic dermatitis. Motivated by research revealing dysbiotic skin microbiomes favoring an overgrowth of Staph aureus on individuals with eczema, Dr. Gallo went one step further and found that the skin of healthy individuals contained higher amounts of two Staphylococcus species — Staphylococcus epidermidis and Staphylococcus hominis — than the skin of eczema patients. These two species not only inhibited the growth of Staph aureus but did so without harming other beneficial members of the skin microbial community. A phase 1 clinical trial in which these two Staphylo-coccus species were isolated from the skin of patients with eczema and then applied to their skin in the form of a personalized probiotic lotion showed that the lotion decreased Staph aureus on the arms of eczema sufferers. Larger clinical studies are now underway.

In a world focused on the gut microbiome and how to diagnose and treat disease by targeting the microbes that live in our intestinal tracts, it can be easy to forget just how important our skin and the microbes that live on it are. Researchers like Chris Callewaert, Rich Gallo, the scientists at Azitra, and many others are leading the way into a new frontier of skincare.

A special thank you to Thermo Fisher Scientific for bringing you the SynBioBeta 2018 Webcast!

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9:00am -MAIN STAGESession: DNA data storage (sponsored by SemiSynBio)____

If we stored all the world’s data in flash memory, we would run out of the raw materials in 25 years, yet all the world’s data could theoretically be stored in a teaspoonful of DNA material. Our panelists share the latest breakthroughs in DNA data storage, and share a vision for how DNA could become your failsafe, lossless backup.

speakers: David Markowitz, IARPA; Rafic Makki, Mubadala Ventures; Hyunjun Park, Catalog DNA; Bill Peck, Twist Bioscience; Victor Zhirnov, Semiconductor Research Corporation

7:30am - Registration and breakfast____

BREAKOUT ROOM R1Sponsored by SynBioBeta

8:30am - MAIN STAGEWelcome____

John Cumbers welcomes you to day 3 of SynBioBeta 2018. He’ll share some highlights from the conference to come, share some exciting news, and give you a sneak preview of what’s in store for 2019.

speaker: John Cumbers,SynBioBeta

8:40am - MAIN STAGEKeynote: Twenty years of synthetic biology: How far are we from 1998?____

Over the past two decades, synthetic biology has gone from concept to reality. The sociopolitical landscape that science finds itself in today is very different from a year ago, let alone twenty years ago. In this keynote session, leaders in our field examine the how and why of the current state of synthetic biology, and consider what this means for the next twenty years.

speaker: Tim Gardner, Riffyn

Schedule Details - Wednesday, October 3

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10:15am - Coffee break____


9:30am - BREAKOUT ROOM R1Office hours with Terri Shieh-Newton (sponsored by Mintz Levin)____

9:30am -MAIN STAGESession talks: Advanced molecular manufacturing, chemicals and materials (sponsored by Ecovative)____

Advanced biomanufacturing is a step change from conventional biological manufacturing processes, with the ability to make a broader range of products faster and more precisely. Learn about synthetic biology approaches that are enabling new classes of bio-based chemicals and materials.

speakers: Charles Dimmler, Checkerspot; Christine Santos, ManusBio; Steve Evans, The Dow Chemical Company; Priti Pharkya, Genomatica; Jens Plassmeier, BASF;


10:45am - MAIN STAGEFocus session: Food 2.0____

In this session, meet the entrepre-neurs that are driving forward the future of sustainable food and agriculture. From vegan pet food to protein-based sweeteners, this session will feature many of the rising stars of the new food movement.

speakers: Ryan Bethencourt, Wild Earth; Ilan Samish, Amai Proteins; Charles Denby, Berkeley Brewing Science; Casey Lippmeier, Conagen; Liz Specht, The Good Food Institute

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12:15pm -Lunch (sponsored by Twist Bioscience)____

Grab a bite and hit the exhibit hall to meet with many of the leading innovators, thinkers, and investors in our community.


12:20pm - BREAKOUT ROOM R1Focus breakout session: Massively parallel systematic discovery in cell-free synthetic biology (sponsored by Arbor Biosciences)____

Cell-free expression has become a powerful tool in synthetic biology for screening assays, protein engineering and constructing gene circuits. This session reviews new screening workflows with integrated bacterial-based cell-free systems for rapid, systematic and massively parallel sample throughput. These robust, versatile approaches hold promise for many design-build-test scenarios.

speakers: Sung Sun Yim, Columbia University; Kyle Watters, California State Berkeley

moderator: Matthew Hymes, Arbor Biosciences

11:50am - MAIN STAGEKeynote panel: Go big or go home - scaling up the biofab (sponsored by Ginkgo Bioworks)____

Living organisms are the product factories of the future. Efficient design and scaling of organisms for production requires new tools and approaches in automation, analytics, and software. Join Ginkgo Bioworks CEO Jason Kelly and other industry leaders for this fireside chat about scaling biological designs at a global scale.

speaker: Christophe Schilling, Genomatica

moderator: Jason Kelly, Gingko Bioworks

11:30am - MAIN STAGEFireside chat: Agriculture’s pivot toward sustaining water, air and oceans____

Pivot Bio’s CEO Karsten Temme talks with the World Economic Forum’s Nishan Degnarain about the future of technology, agriculture, and the oceans. Learn how companies like Pivot Bio aim to help farmers not only feed our growing world, but also halt or even reverse the air and water quality changes that come with traditional agriculture.

speakers: Karsten Temme, Pivot Bio; Nishan Degnarain, World Economic Forum

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12:20pm - PICNIC 1 ON THE LAWN

Picnic lunch and learn: Regulation and oversight of synthetic biology (Science Policy Consulting LLC)____

The conduct of synthetic biology largely follows U.S. government guidance for biosafety (e.g. the NIH Guidelines) and biosecurity (e.g. the Screening Framework Guidance for synthetic DNA providers). How do emerging practices and products challenge these policies, and what to do about it? This session will discuss regulation by the FDA, EPA, and USDA, including the responsibilities of each agency and how this “Coordinated Framework” has evolved over time.

12:20pm - BREAKOUT ROOM R3Lunch and learn: Building synthetic biology companies that scale (sponsored by Mayfield/ WSBR)____

In this Lunch and Learn, you’ll talk with leading investors and experienced entrepreneurs about the biggest challenges and pitfalls facing synthetic biology companies as they scale. Combining their many years of experience, they’ll share their insights on product-market matching, choosing partners, company structuring, human resources, and much more.

speakers: Maneesh Jain, Cirina; Raj Judge, Wilson Sonsini Goodrich & Rosati; Ursheet Parikh, Mayfield Fund; Arvind Gupta, Indie Bio; Diego Rey, Life Sciences Entrepeneur

12:20pm - BREAKOUT ROOM R2Workshop: Lab data to machine learning in 30 seconds (sponsored by Riffyn)____

Digital biology enables researchers to spend less time manipulating large datasets and more time analyzing it. In this workshop, Riffyn scientists share an approach to experimentation that may have you re-thinking the very nature of the scientific experiment.

1:25pm - MAIN STAGELightning talks, 2____

Get a panoramic overview of the cutting edge landscape of synthetic biology in this rapid session of four-minute talks with scientific leaders, innovators of the bioeco-nomy, and the best and brightest newcomers.

speakers: Todd Bixby, Intrexon; Troy Lionberger, Berkeley Lights; Ben Borgo, Agilent; Trevor Martin, Mammoth Diagnostics; Daniel Arlow, Ansa Biotechnologies; Gabriel Lopez, Synvivia; Terri Shieh-Newton, Mintz Levin; Yuki Quin, Genscript; Felix Moser, Synlife; Max Ryadnov, NPL

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1:25pm - BREAKOUT ROOM R3Focus session: Engineered cancer immunotherapies (sponsored by Distributed Bio)____

Synthetic biology is key to many immunotherapies already saving the lives of cancer patients. This session examines the state-of-the-art and previews just how and when cancer immunotherapy could go main-stream by spotlighting some of the most innovative companies and new approaches in this pivotal space.

speakers: Alex Franzusoff, PactPharma; Daniel Georgiev, XENO Cell Innovations; Jeroen Blokhuis, Parker Institute for Cancer Immunotherapy; Jacob Glanville, Distributed Bio

moderator: Jacob Glanville, xDistributed Bio

2:10pm -Break____



1:25pm - BREAKOUT ROOM R2Focus breakout session: Biosecurity by design: traceability & bio on the blockchain____

With technology advancing at an accelerating rate, we must take biosecurity as a priority starting at the design stage. Here we talk about blockchain and its application in biotechnology, with a look at how this technology of traceability can be used as a tool to help ensure biosafety and biosecurity.

speakers: Jessica Green, Phylagen; Michael Molitor, Uniti; Bob Weinstein, Robertet USA

1:25pm - BREAKOUT ROOM R1Focus panel: Decentralization of Tech-nology and Scale: What’s Your Bio Strategy?____

The biopharmaceutical industry has been the expert in scaling biological technologies. How will decentralization impact the way biopharmaceutical companies operate? What happens when you begin applying synthetic biology tools to bioprocessing? What can syntheticbiology companies learn from partnering with big biopharma and life science tools companies? Come learn how big biopharma companies are re-imagining their businesses in the face of synthetic biology tools, decentralization, gene circuit design, and large scale DNA synthesis.

speakers: Jessie Dhanju, Beckman Coulter, Inc.; Leslie Mitchell, Neo Chromosome; Alec Nielsen, Asimov; Jared Stephens

moderator: Karl Schmieder, messagingLAB

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2:15pm -BREAKOUT ROOM R1Focus panel: Chemicals and materials: What’s your bio strategy?____

Though chemical manufacturing is a $5 trillion / year industry, its mem-bers face threats and opportunities ranging from the tactical to the exis-tential. Synthetic biology is arguably the best – in some cases, the only – means to address them. This session will explore synthetic biology as focus area for chemistry and materials, and its potential to help innovate for lower costs, improved properties, and new products.

speakers: Jared Stephens, GE Healthcare; Pulakesh Mukherjee, BASF

moderator: Cas Smith,Biofabricate

2:15pm - BREAKOUT ROOM R2Focus breakout session: Design and synthetic biology____

Design thinking can help us understand how and where synthetic biology fits into the broader context of society—a question that does not always have obvious answers. This session explores what design thinking is, shares real-life examples and outcomes, and offers practical wisdom for putting “Design” into your design-build-test-learn cycle.

speaker: Natsai Audrey Chieza, Faber Futures

moderator: Christina Agapakis, Ginkgo Bioworks

2:15pm -MAIN STAGESession talks: New tools of the trade: Cell-free synthetic biology, engineered enzymes, and antibodies____

Cell-free approaches promise simpler and faster engineering solutions with greater design freedom. This panel will examine the impact of cell-free synthetic biology in protein engineering, metabolic engineering, artificial cell engineering, and more.

speakers: Thomas Meany, Cell-Free Technology; Paul Freemont, SynbiCITE; Zack Sun; Matthew Hymes, Mycro Array

2:15pm - BREAKOUT ROOMS R3Focus breakout session: Science fiction and synthetic biology____

Science fiction is a powerful inspiration to innovators like Elon Musk and countless others who use emerging technologies like synthetic biology in creating our shared future. This session focuses on science fiction as a tool for reflection, discourse, and inspiration, all of which are essential for synthetic biology to evolve in the most ethical, meaningful, and awe-inspiring ways.

speakers: Karl Schmieder, messagingLAB; John Sundman, GATTACA; Vasil Hnatiuk

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3:05pm - MAIN STAGEPanel: Genetic literacy____

As the products of synthetic biology make their way to consumers, it’s increasingly important that we all understand the science and societal implications of human and agricultural genetic and biotechnology research. Our panelists share learnings to help the public, media, practitioners, and policymakers seek common values in the ethical pursuit of breakthrough genetic technologies.

speakers: Robert Friedman, J. Craig Venter Institute (JCVI); Natsai Audrey Chieza, Faber Futures; Jon Entine, Genetic Literacy Project

moderator: Meagan Lizarazo, iGEM Foundation

3:05pm - BREAKOUT ROOM R1Focus panel: Companies that change the rules of the game (sponsored by Civilization Ventures)____

The sweep of synthetic biology innovation is made possible by the convergence of technical and social advances, and these panelists are experts in recognizing and leveraging them. Come dream big and surf the exponential with these leaders of the bioeconomy, who are disrupting the technologies underpinning synthet-ic biology, tackling extraordinary human problems, and accelerating sustainable ventures.

speakers: Zal Bilimoria, Refactor Capital; Laura Deming, The Longevity Fund; James Currier, NFX; Shahram Seyedin-Noor, Civilization Ventures; Ryan Bethencourt, Wild Earth Pets

moderator: Tim Brears, Evonetix

3:05pm - BREAKOUT ROOM R2Focus panel: Consumer packaged goods: What’s your bio strategy?____

While bio-based products are in the minority today, it is conceivable that in ten years most consumer packaged goods (CPGs) will be augmented or created by what we call synthetic biology. This session shares how leading CPG companies are developing their bio strategies to stay ahead of the curve.

speakers: Elizabeth Wu, Johnson & Johnson

moderator: Mark Bünger, Innovative Lab


3:00pm - Break____


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3:05pm - BREAKOUT ROOM R3Focus breakout session: Biodiversity and synthetic biology____

Synthetic biology has a vital role to play in conservation, sustainability, and the equitable sharing of the planet’s biodiversity, although little consensus exists for how to real-ize this. This session explores the technical and social opportunities for the synthetic biology community to nurture and sustain the biological richness that surrounds us.

speakers: Charlie Yeo, Sarawak Biodiversity Centre; Edward Perello, Arkurity; Ryan Phelan, Revive and Restore


3:50pm - MAIN STAGEFeatured spotlight, Mother Dirt____

speaker: Jasmina Aganovic, Mother Dirt

3:55pm - Coffee break and workshops____

Take a break and check out the exhibit hall, where you can make valuable connections and learn about the latest synthetic biology technologies. Workshops will also be running during the breaks.

3:55pm - BREAKOUT ROOM R1Workshop: Partnering opportunities with Procter & Gamble (sponsored by Procter & Gamble)____

What does synthetic biology look like to a consumer products company like Procter & Gamble? Come join scientists from across P&G divisions to learn more about our interest in biomaterials, applications of these, partnering opportunities, best practices, and challenges in realizing our future product aspirations.

speaker: Amy Trejo, Procter and Gamble

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3:55pm - BREAKOUT ROOM R3Workshop: A New Approach to Classifying Industrial Microorganisms – moving the discussion beyond ‘Natural’ vs GMO (sponsored by DuPont)____

Genetic engineering of industrial microorganisms is well established, yet continues to generate concerns on the part of the public, regulatory bodies and customers of the biotech-nology industry. The designation of microbial strains as either genetically modified (‘GMO’) or not, is overly simplistic and fails to capture the genetic diversity of industrial micro-organisms currently in commerce. We will discuss an ASTM effort to develop a systematic classification system that differentiates between the many sub-types of industrial microorganism.

speaker: Joseph McAuliffe, DuPont

4:40pm - MAIN STAGEFireside chat: Why aren’t there more scientists in politics?____

Government funding and roadmaps largely guide science in society, yet politicians usually lack the scientific background to fully appreciate the implications of their decisions. Can a new influx of scientists-turned-pol-iticians help save politics from de-funding the research we all depend upon? What’s the role of every scientist in politics?

speakers: Michael Eisen, UC Berkeley, PLOS; David Ewing Duncan, Journalist and Author

5:00pm - MAIN STAGEKeynote panel: Automation and machine learning: The impact on biopharma____

The tools of synthetic biology are changing the way biopharma pursues R&D, giving access to problems that were out of reach just a decade ago. This fireside chat among industry leaders examines trends in biophar-ma, what tools like AI can and cannot do, the role of miniaturization and advanced technologies in drastically scaling experimentation, and what bottlenecks persist.

speakers: Mark Fischer-Colbrie, Labcyte; John Baldoni, GSK

moderator: Aishani Aatresh, Distributed Bio


3:55pm - BREAKOUT ROOM R2Workshop: The future of farming (sponsored by Pivot Bio)____

As agriculture pivots into the age of synthetic biology, the modern farmer stands at the center of some our greatest environmental challenges. This panel explores how synthetic biology can give farmers the tools to slow or reverse the air and water pollution that comes with current agricultural practices, while also feeding our growing population.

speaker: Keira Havens, Pivot Bio

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5:20pm - MAIN STAGEPanel: The future of DNA synthesis (sponsored by Molecular Assemblies)____

DNA synthesis is arguably the key enabling technology fueling the synthetic biology industry, making possible technologies and applica-tions previously unheard of. This panel of innovators is taking DNA synthesis to the next level. Learn what capabilities are just around the corner, how they will further disrupt biotechnology, and new applications they will make possible.

speakers: Michael Kamdar, Molecular Assemblies; Sarah Milsom, Touchlight; Andrew Hessel, Autodesk; Leslie Mitchell, Neo Chromosomes; Rob Carlson, Bioeconomy Capital

moderator: John Cumbers, SynBioBeta


6:00pm - MAIN STAGEWrap up____

speaker: John Cumbers, SynBioBeta

Wed Oct 3rd 7:30pm-10:00pm

525 Market Street San Francisco

SynBioBeta After Party @The AWS Loft

Drinks, Lite Appetizers, Friends and Fun.

You belong to a passionate community solving challenges with synthetic biology.

SynbiCITE, accelerating and promoting the commercial exploitation of synthetic biology

We offer innovation and access to a broad array of resources in the UK, designed to help translate university-based research and pre-seed concepts into commercial products, tools, processes and services.

Get in touch to find out how we can help you.

� +44 (0)20 7594 9902

� [email protected]

� www.synbicite.com

Harnessing the power of synthetic biology


2019

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Faster, Better, Cheaper Reading and Writing of DNA...

Data from Rob Carlson of Bioeconomy Capital and SynBioBeta

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2019 Synthetic Biology Investment Totals Over $1B in the Last 12 Months

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2019More Than $3B Projected Synthetic Biology Investments in 2018

Data from SynBioBeta

Synthego.com/cells

CRISPRfor All


2019 What’s Planned for SynBioBeta 2019:

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2019Planned Newsletter Editorial Topics for 2019:

1.2.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The Synbio Stack, Part 2 1.9.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Synthetic biology in China1.16.19 . . . . . . . . . . . . . . . . . . . . . . . D.I.Y biology: What you need to know1.23.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Automation1.30.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The Synbio Stack, Part 32.6.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Tech transfer2.13.19 . . . . . . . . . . . . . . . . . . . . . . . . . Moving from academia to industry2.20.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Start-up 101, Part 12.27.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Synthetic biology in India3.6.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Entrepreneur How-To3.13.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Women entrepreneurs3.20.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Start-up 101, Part 23.27.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Patents and IP4.3.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The Synbio Stack, Part 44.10.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Synthetic biology in the UK4.17.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Founders at Work, Part 14.24.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Cell-free technologies5.1.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Designer proteins5.8.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The Synbio Stack, Part 55.15.19 . . . . . . . . . . . . . . . . . . . . . . . . . Synthetic biology in greater Europe5.22.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Founders at Work, Part 25.29.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .DIY biology: safety6.5.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The Synbio stack, Part 66.12.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Genome editing6.19.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Chemicals and Materials6.26.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Founders at Work, Part 37.3.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The Synbio Stack, Part 7

7.10.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DNA synthesis7.17.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Founders at Work, Part 47.24.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Biopharma and Healthcare7.31.19 . . . . . . . . . . . . . . . . . . . . . . . . . . Synthetic biology in Latin America8.7.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The Synbio Stack, Part 88.14.19 . . . . . . . . . . . . . . . . . . . . . . . . . . Deep learning/machine learning6.21.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Food and beverages8.28.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Founders at Work, Part 59.4.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The Synbio Stack, Part 99.11.19 . . . . . . . . . . . . . . . . . . . . . . . . . .Personal and Household Products9.18.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . Microbiome engineering, part 19.25.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Founders at Work, Part 710.2.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Conference highlights10.9.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The Synbio Stack, Part 1010.16.19. . . . . . . . . . . . . . . . . . . . . . . . . . . Microbiome engineering, part 210.23.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Founders at Work, Part 8 10.30.19 . . . . . . . . . . . . . . . . . . . . . . . . . Blockchain and synthetic biology11.6.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The Synbio Stack, Part 1111.13.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . Microbiome engineering, part 311.20.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Agriculture11.27.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Investing 10112.3.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The Synbio Stack, Part 12 12.4.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . Microbiome engineering, part 4 12.11.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Pitching 101 12.18.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The year in review 12.25.19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2019 prospectus


2019 SynBioBeta Thought-Leadership

Thought-Leadership Retreats

Founders’ Breakfast Series

Thought-Leadership Dinners

Fortune 500 Outreach

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Fortune 500 Outreach

SynBioBeta Strategic Growth Opportunities

Courses

Consulting

Job Postings

Customized Industry Innovation Tools


2019 SynBioBeta Digital Media: Thought-Leadership & Lead Generation

Sponsored Newsletters & Content

The SynBioBeta Podcast

Videos & Webinars

Reports & Whitepapers

What’s Your Bio Strategy

For:Diversified Commodity, Specialty, and Fine Chemicals and Materials

What’s Your Bio Strategy For:Personal and Household Products

93

2019

Reports & Whitepapers

SynBioBeta E-mail Newsletter

Newsletter Statistics:

Subscriber Growth:

Subscribers

6,3802018 Average Open Rate

30.10%2018 Average Click Rate

13.44%


2019 SynBioBeta Social Media Presence

Twitter Followers

Facebook LikesLinkedIn Group Members

Social Media Statistics:

Twitter Followers

15,174LinkedIn Group Members

3,003

Facebook Like

3,861

Technologies Enabling the Future:

BetaSpace 2019

Contact [email protected].

April 11–12Los Angeles, CaliforniaA parallel universe where Burning Man and The Consumer Electronics Show collide, showcasing how humanity can thrive off-planet.

Find out more at thermofisher.com/geneartproducts

• New LentiArray™ CRISPR libraries • Complete suite of genome editing products - Enabling everything from high throughput screening to precision editing• Designer TALENs

• Custom cell line engineering services

Comprehensive and Innovative SynBio Solutionswith Invitrogen™ Gene Editing and GeneArt™ Gene Synthesis

Design, deliver, express, and engineer – all in one place

• Gene synthesis, fragments, and libraries - Now with quicker turnaround time • Complete gene-to-protein services

GeneArt ™ It Your gene, your way

Visit us at booth #7.

Oct. 1-3San Francisco

tech, meet bio. bio, meet tech. - synbiobeta 2018€¦ · welcome to synbiobeta 2018 — our...

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