NURS 1566 Clinical Form 3: Clinical Medications Worksheets(You will need to make additional copies of these forms)

Generic NameMethimazole

Trade NameTapazole

ClassificationAntithyroid agents

Dose20mg

RoutePO

Time/frequencyQ Day

Peak4-10 weeks

Onset1 week

Durationweeks

Normal dosage range15-60 mg/day as a single dose or divided doses for 6-8 weeks.

Why is your patient getting this medicationHyperthyroid

For IV meds, compatibility with IV drips and/or solutionsN/A

Mechanism of action and indications(Why med ordered)Inhibits the synthesis of thyroid hormones. Indicated for palliative treatment of hyperthyroidism.

Nursing Implications (what to focus on) Contraindications/warnings/interactions.Contraindicated in hypersensitivity. Use cautiously in patients >40 yrs. because of increased risk of agranulocytosis. No relevant interactions.Common side effectsRash

Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically)None

Lab value alterations caused by medicineThyroid function studies should be monitored prior to and during therapy. WBC counts and differentials should be monitored due to increased risk of agranulocytosis. May cause increased AST, ALT, LDH, alkaline phosphatase, serum bilirubin, and prothrombin time.Be sure to teach the patient the following about this medicationTake around the clock. If a dose is missed, take as soon as remembered, if almost time for next dose, take both doses together. Monitor weight and notify healthcare provider of significant changes.May cause drowsiness. Advise pt to consult health care professional regarding dietary souces of iodine and to report sore throat, fever, chills, headache, malaise, weakness, yellowing of eyes or skin, unusual bleeding or bruising, rash, or symptoms of hyper or hypothyroidism.

Nursing Process- Assessment(Pre-administration assessment)Assess pt for development of hypothyroidism (intolerance to cold, constipation, dry skin, headache, listlessness, tiredness, or weakness).

AssessmentWhy would you hold or not give this med?If signs of hypothyroid were present

EvaluationCheck after givingDecrease in severity of symptoms of hyperthyroidism, return of thyroid studies to normal