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Print ISSN: 0022-1767 Online ISSN: 1550-6606. All rights reserved.1451 Rockville Pike, Suite 650, Rockville, MD 20852The American Association of Immunologists, Inc.,

is published twice each month byThe Journal of Immunology

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Table of ContentsTable of Contents

6677 In This Issue

Brief Reviews6679 Mechanisms of Immunity in Hydatid Disease: Implications for Vaccine Development

Wenbao Zhang, Allen G. Ross, and Donald P. McManus

Cutting Edge6687 Cutting Edge: Experimentally Induced Immune Activation in Natural Hosts of Simian Immunodeficiency

Virus Induces Significant Increases in Viral Replication and CD4� T Cell DepletionIvona Pandrea, Thaidra Gaufin, Jason M. Brenchley, Rajeev Gautam, Christopher Monjure, Aarti Gautam,Clint Coleman, Andrew A. Lackner, Ruy M. Ribeiro, Daniel C. Douek, and Cristian Apetrei

6692 Cutting Edge: Eosinophils Do Not Contribute to Respiratory Syncytial Virus Vaccine-Enhanced DiseaseElaine M. Castilow, Kevin L. Legge, and Steven M. Varga

6697 Cutting Edge: Helminth Infection Induces IgE in the Absence of �- or �-Chain ExpressionGeorgia Perona-Wright, Katja Mohrs, Justin Taylor, Colby Zaph, David Artis, Edward J. Pearce, and Markus Mohrs

6702 Cutting Edge: FimH Adhesin of Type 1 Fimbriae Is a Novel TLR4 LigandKaren L. Mossman, M. Firoz Mian, Nicole M. Lauzon, Carlton L. Gyles, Brian Lichty, Randy Mackenzie, Navkiran Gill,and Ali A. Ashkar

6707 Cutting Edge: Programmed Death-1/Programmed Death Ligand 1 Interaction Regulates the Inductionand Maintenance of Invariant NKT Cell AnergyWoo-Sung Chang, Ji-Yeon Kim, Yeon-Jeong Kim, Yun-Sun Kim, Jung-Mi Lee, Miyuki Azuma, Hideo Yagita,and Chang-Yuil Kang

Cellular Immunology and Immune Regulation6711 Interaction of Monocytes with NK Cells upon Toll-Like Receptor-Induced Expression of the NKG2D

Ligand MICAMercedes Kloss, Patrice Decker, Katrin M. Baltz, Tina Baessler, Gundram Jung, Hans-Georg Rammensee,Alexander Steinle, Matthias Krusch, and Helmut R. Salih

VOL. 181 � NO. 10 � November 15, 2008 � Pages 6677–7432

On the cover: Cutaneous lesions in MRL-Faslpr mice (5 mo of age) resemble the verrucoid variant of human discoid lupus,characterized by interface vacuolar changes with apoptotic keratinocytes, acanthosis with hyperkeratosis/hypergranulosisand follicular plugging, and a superficial and deep lymphohistiocytic infiltrate with associated scarring alopecia (referto Fig. 1 on page 7369; H&E, �40). Menke, J., M.-Y. Hsu, K. T. Byrne, J. A. Lucas, W. A. Rabacal, B. P. Croker,X.-H. Zong, E. R. Stanley, and V. R. Kelley. 2008. Sunlight triggers cutaneous lupus through a CSF-1-dependentmechanism in MRL-Faslpr mice. J. Immunol. 181: 7367–7379.

The Journal of Immunology (ISSN 0022-1767) is published twice each month by The American Association of Immunologists,Inc., 9650 Rockville Pike, Bethesda, MD 20814-3994, Phone: 301-634-7197, Fax: 301-634-7829. Subscription term: Newsubscriptions and renewals begin January 1 and expire one year later (see http://www.jimmunol.org/subscriptions for prices anddetails). A special rate is available to members of The American Association of Immunologists, Inc. (see http://www.aai.org/membership). The American Association of Immunologists, Inc., is not responsible for undeliverable issues. Replacement issuescan be obtained, if available, at the regular price of single issues (see http://www.jimmunol.org/pdf/single_issue_purchase.pdf).Reprints of individual articles are available only from authors. Periodicals postage paid at Bethesda, MD 20814-3994, and atadditional mailing offices. Country of origin U.S.A. Printed on acid-free recyclable paper. Postmaster: Send address changes60 days in advance to The Journal of Immunology, Subscription Department, 9650 Rockville Pike, Bethesda, MD 20814-3994.Copyright © 2008 by The American Association of Immunologists, Inc.

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6720 TLR Ligands in the Local Treatment of Established Intracerebral Murine GliomasOliver M. Grauer, Johan W. Molling, Erik Bennink, Liza W. J. Toonen, Roger P. M. Sutmuller, Stefan Nierkens,and Gosse J. Adema

6730 Lipopolysaccharide-Induced Expression of NAD(P)H:Quinone Oxidoreductase 1 and Heme Oxygenase-1Protects against Excessive Inflammatory Responses in Human MonocytesStuart A. Rushworth, David J. MacEwan, and Maria A. O’Connell

6738 The Common �-Chain Cytokines IL-2, IL-7, IL-15, and IL-21 Induce the Expression of ProgrammedDeath-1 and Its LigandsAudrey L. Kinter, Emily J. Godbout, Jonathan P. McNally, Irini Sereti, Gregg A. Roby, Marie A. O’Shea,and Anthony S. Fauci

6747 Aging Impairs IFN Regulatory Factor 7 Up-Regulation in Plasmacytoid Dendritic Cells duringTLR9 ActivationHeather W. Stout-Delgado, Xin Yang, Wendy E. Walker, Bethany M. Tesar, and Daniel R. Goldstein

6757 Reversible Blockade of Thymic Output: An Inherent Part of TLR Ligand-Mediated Immune ResponseThomas Demoulins, Ali Abdallah, Nadia Kettaf, Marie-Laurence Baron, Casimiro Gerarduzzi, Dominique Gauchat,Sophie Gratton, and Rafick-Pierre Sekaly

6770 Adaptable TCR Avidity Thresholds for Negative SelectionMilica Stojakovic, Laura I. Salazar-Fontana, Zohreh Tatari-Calderone, Vladimir P. Badovinac, Fabio R. Santori,Damian Kovalovsky, Derek Sant’Angelo, John T. Harty, and Stanislav Vukmanovic

6779 Regulatory Roles for NKT Cell Ligands in Environmentally Induced AutoimmunityJaya Vas, Jochen Mattner, Stewart Richardson, Rachel Ndonye, John P. Gaughan, Amy Howell, and Marc Monestier

6789 Enhanced Early Expansion and Maturation of Semi-Invariant NK T Cells Inhibited AutoimmunePathogenesis in Congenic Nonobese Diabetic MiceAito Ueno, Jianxiong Wang, Lu Cheng, Jin S. Im, Yan Shi, Steven A. Porcelli, and Yang Yang

6797 IFN-� Production by TLR4-Stimulated Innate Immune Cells Is Negatively Regulated by GSK3-�Huizhi Wang, Carlos A. Garcia, Kunal Rehani, Caglar Cekic, Pascale Alard, Denis F. Kinane, Thomas Mitchell,and Michael Martin

6803 Ion Channels Modulating Mouse Dendritic Cell FunctionsNicole Matzner, Irina M. Zemtsova, Nguyen Thi Xuan, Michael Duszenko, Ekaterina Shumilina, and Florian Lang

6810 Caspase-6 Regulates B Cell Activation and Differentiation into Plasma CellsChie Watanabe, Geraldine L. Shu, Timothy S. Zheng, Richard A. Flavell, and Edward A. Clark

6820 The Host Environment Regulates the Function of CD8� Graft-versus-Host-Reactive Effector CellsRonjon Chakraverty, Barry Flutter, Farnaz Fallah-Arani, Hyeon-Seok Eom, Terry Means, Giovanna Andreola,Sebastian Schwarte, Jennifer Buchli, Pete Cotter, Guiling Zhao, and Megan Sykes

6829 Experimental Antibody Therapy of Liver Metastases Reveals Functional Redundancy between Fc�RIand Fc�RIVMarielle A. Otten, Gerben J. van der Bij, Sjef J. Verbeek, Falk Nimmerjahn, Jeffrey V. Ravetch, Robert H. J. Beelen,Jan G. J. van de Winkel, and Marjolein van Egmond

6837 IL-21 Stimulates Human Myeloma Cell Growth through an Autocrine IGF-1 LoopEmmanuelle Menoret, Sophie Maïga, Geraldine Descamps, Catherine Pellat-Deceunynck, Caroline Fraslon,Melania Cappellano, Philippe Moreau, Regis Bataille, and Martine Amiot

6843 MHC Variant Peptide-Mediated Anergy of Encephalitogenic T Cells Requires SHP-1Heather A. Wasserman, Carrie D. Beal, Yan Zhang, Ning Jiang, Cheng Zhu, and Brian D. Evavold

6850 Polysialic Acid, a Glycan with Highly Restricted Expression, Is Found on Human and Murine Leukocytesand Modulates Immune ResponsesPenelope M. Drake, Jay K. Nathan, Christina M. Stock, Pamela V. Chang, Marcus O. Muench, Daisuke Nakata,J. Rachel Reader, Phung Gip, Kevin P. K. Golden, Birgit Weinhold, Rita Gerardy-Schahn, Frederic A. Troy II,and Carolyn R. Bertozzi

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6859 Dendritic Cell Differentiation Induced by a Self-Peptide Derived from Apolipoprotein ETracey A. Stephens, Enayat Nikoopour, Beverly J. Rider, Matilde Leon-Ponte, Thu A. Chau, Sebastian Mikolajczak,Pratibha Chaturvedi, Edwin Lee-Chan, Richard A. Flavell, S. M. Mansour Haeryfar, Joaquin Madrenas,and Bhagirath Singh

6872 Antiviral-Activated Dendritic Cells: A Paracrine-Induced Response StateAntonio V. Bordería, Boris M. Hartmann, Ana Fernandez-Sesma, Thomas M. Moran, and Stuart C. Sealfon

6882 PI4P5-Kinase I� Is Required for Efficient HIV-1 Entry and Infection of T CellsMarta Barrero-Villar, Jonathan Barroso-Gonzalez, J. R. Cabrero, Monica Gordon-Alonso, Susana Alvarez-Losada,M. A. Munoz-Fernandez, Francisco Sanchez-Madrid, and Agustín Valenzuela-Fernandez

6889 Differential Regulatory Function of Resting and Preactivated Allergen-Specific CD4�CD25� RegulatoryT Cells in Th2-Type Airway InflammationKanako Saito, Mie Torii, Ning Ma, Tomoko Tsuchiya, Linan Wang, Tomohide Hori, Daisuke Nagakubo, Nao Nitta,Shiro Kanegasaki, Kunio Hieshima, Osamu Yoshie, Esteban C. Gabazza, Naoyuki Katayama, Hiroshi Shiku,Kagemasa Kuribayashi, and Takuma Kato

6898 Human CD4�CD25�Foxp3� Regulatory T Cells Do Not Constitutively Express IL-35Emilie Bardel, Frederique Larousserie, Pascaline Charlot-Rabiega, Aurore Coulomb-L’Hermine, and Odile Devergne

6906 Neuropeptide Y Is Expressed by Rat Mononuclear Blood Leukocytes and Strongly Down-Regulatedduring InflammationJulia Holler, Anna Zakrzewicz, Andreas Kaufmann, Jochen Wilhelm, Gabriele Fuchs-Moll, Hartmut Dietrich,Winfried Padberg, Jitka Kuncova, Wolfgang Kummer, and Veronika Grau

6913 Transgenic Mice Expressing Dominant-Negative Bright Exhibit Defects in B1 B CellsJamee C. Nixon, Scott Ferrell, Cathrine Miner, Athenia L. Oldham, Ute Hochgeschwender, and Carol F. Webb

6923 CD8�CD205� Splenic Dendritic Cells Are Specialized to Induce Foxp3� Regulatory T CellsSayuri Yamazaki, Diana Dudziak, Gordon F. Heidkamp, Christopher Fiorese, Anthony J. Bonito, Kayo Inaba,Michel C. Nussenzweig, and Ralph M. Steinman

6934 Rapid and Selective Expansion of Nonclonotypic T Cells in Regulatory T Cell-Deficient, ForeignAntigen-Specific TCR-Transgenic Scurfy Mice: Antigen-Dependent Expansion and TCR AnalysisRahul Sharma, Angela Chiao-Ying Ju, John T. Kung, Shu Man Fu, and Shyr-Te Ju

6942 Suppression of Murine Allergic Airway Disease by IL-2:Anti-IL-2 Monoclonal Antibody-InducedRegulatory T CellsMark S. Wilson, John T. Pesce, Thirumalai R. Ramalingam, Robert W. Thompson, Allen Cheever, and Thomas A. Wynn

6955 Imatinib Mesylate Inhibits CD4�CD25� Regulatory T Cell Activity and Enhances ActiveImmunotherapy against BCR-ABL� TumorsNicolas Larmonier, Nona Janikashvili, Collin James LaCasse, Claire Billerey Larmonier, Jessica Cantrell, Elaine Situ,Tamara Lundeen, Bernard Bonnotte, and Emmanuel Katsanis

6964 IFN-�-Dependent Regulatory Circuits in Immune Inflammation Highlighted in DiabetesBoris Calderon, Anish Suri, Xiaoou O. Pan, Jason C. Mills, and Emil R. Unanue

6975 Targeting CD4 Coreceptor Expression to Postselection Thymocytes Reveals That CD4/CD8 LineageChoice Is neither Error-Prone nor StochasticStanley Adoro, Batu Erman, Sophia D. Sarafova, Francois Van Laethem, Jung-Hyun Park, Lionel Feigenbaum,and Alfred Singer

6984 CD4� and CD8� T Cells Exhibit Differential Requirements for CCR7-Mediated Antigen Transportduring Influenza InfectionAlex K. Heer, Nicola L. Harris, Manfred Kopf, and Benjamin J. Marsland

6995 Dynamin 2 Regulates Granule Exocytosis during NK Cell-Mediated CytotoxicityLaura N. Arneson, Colin M. Segovis, Timothy S. Gomez, Renee A. Schoon, Christopher J. Dick, Zhenkun Lou,Daniel D. Billadeau, and Paul J. Leibson

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7002 Tetraspanins Regulate ADAM10-Mediated Cleavage of TNF-� and Epidermal Growth FactorCecile Arduise, Toufik Abache, Lei Li, Martine Billard, Aurelie Chabanon, Andreas Ludwig, Philippe Mauduit,Claude Boucheix, Eric Rubinstein, and Francois Le Naour

7014 Thymocyte-Dendritic Cell Interactions near Sources of CCR7 Ligands in the Thymic CortexEna Ladi, Tanja A. Schwickert, Tatyana Chtanova, Ying Chen, Paul Herzmark, Xinye Yin, Holly Aaron,Shiao Wei Chan, Martin Lipp, Badrinath Roysam, and Ellen A. Robey

Molecular and Structural Immunology7024 A Novel C1q Family Member of Amphioxus Was Revealed to Have a Partial Function of Vertebrate

C1q MoleculeYanhong Yu, Huiqing Huang, Yan Wang, Yingcai Yu, Shaochun Yuan, Shengfeng Huang, Minming Pan, Kaixia Feng,and Anlong Xu

7033 CD45 Down-Regulates Lck-Mediated CD44 Signaling and Modulates Actin Rearrangement in T CellsNelson K. Y. Wong, Jacqueline C. Y. Lai, Darlene Birkenhead, Andrey S. Shaw, and Pauline Johnson

7044 Hyaluronan Induces Cell Death in Activated T Cells through CD44Brian Ruffell and Pauline Johnson

7055 Negative Regulation of TCR Signaling by Linker for Activation of X Cells viaPhosphotyrosine-Dependent and -Independent MechanismsMichael J. Shapiro, Chau T. Nguyen, Haig Aghajanian, Weiguo Zhang, and Virginia Smith Shapiro

7062 Processing of an Antigenic Sequence from IgG Constant Domains for Presentation by MHC Class IIMorten Flobakk, Ingunn B. Rasmussen, Elin Lunde, Terje Frigstad, Gøril Berntzen, Terje E. Michaelsen, Bjarne Bogen,and Inger Sandlie

Immunogenetics7073 NKG2D-RAE-1 Receptor-Ligand Variation Does Not Account for the NK Cell Defect in Nonobese

Diabetic MiceLisa M. Maier, Sarah K. Howlett, Kara M. Rainbow, Jan Clark, Joanna M. M. Howson, John A. Todd,and Linda S. Wicker

Host Defense7081 Induction of TRAIL- and TNF-�-Dependent Apoptosis in Human Monocyte-Derived Dendritic Cells by

Microfilariae of Brugia malayiRoshanak Tolouei Semnani, Priyanka Goel Venugopal, Lily Mahapatra, Jason A. Skinner, Francoise Meylan,Daniel Chien, David W. Dorward, Damien Chaussabel, Richard M. Siegel, and Thomas B. Nutman

7090 Respiratory Epithelial Cells Convert Inactive Vitamin D to Its Active Form: Potential Effects onHost DefenseSif Hansdottir, Martha M. Monick, Sara L. Hinde, Nina Lovan, Dwight C. Look, and Gary W. Hunninghake

7100 Aspergillus Conidia Activate the Complement by the Mannan-Binding Lectin C2 Bypass MechanismChantal Dumestre-Perard, Bertrand Lamy, Delphine Aldebert, Catherine Lemaire-Vieille, Renee Grillot, Jean-Paul Brion,Jean Gagnon, and Jean-Yves Cesbron

7106 Histoplasma capsulatum Cyclophilin A Mediates Attachment to Dendritic Cell VLA-5Francisco J. Gomez, Robyn Pilcher-Roberts, Arash Alborzi, and Simon L. Newman

7115 IL-15 Links TLR2/1-Induced Macrophage Differentiation to the Vitamin D-DependentAntimicrobial PathwayStephan R. Krutzik, Martin Hewison, Philip T. Liu, Juan Antonio Robles, Steffen Stenger, John S. Adams,and Robert L. Modlin

7121 A Novel Role for Neutrophils As Critical Activators of NK CellsRoman Sporri, Nicole Joller, Hubert Hilbi, and Annette Oxenius

7131 TNF-� Is a Positive Regulatory Factor for Human V�2V�2 T CellsHaishan Li, Kun Luo, and C. David Pauza

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7138 Species-Specific Interaction of Streptococcus pneumoniae with Human Complement Factor HLing Lu, Zhuo Ma, T. Sakari Jokiranta, Adeline R. Whitney, Frank R. DeLeo, and Jing-Ren Zhang

7147 Role of Human CD36 in Bacterial Recognition, Phagocytosis, and Pathogen-InducedJNK-Mediated SignalingIrina N. Baranova, Roger Kurlander, Alexander V. Bocharov, Tatyana G. Vishnyakova, Zhigang Chen, Alan T. Remaley,Gyorgy Csako, Amy P. Patterson, and Thomas L. Eggerman

7157 NOD2-Deficient Mice Have Impaired Resistance to Mycobacterium tuberculosis Infection throughDefective Innate and Adaptive ImmunityMaziar Divangahi, Serge Mostowy, Francois Coulombe, Robert Kozak, Loïc Guillot, Frederic Veyrier, Koichi S. Kobayashi,Richard A. Flavell, Philippe Gros, and Marcel A. Behr

7166 The ESX-5 Secretion System of Mycobacterium marinum Modulates the Macrophage ResponseAbdallah M. Abdallah, Nigel D. L. Savage, Maaike van Zon, Louis Wilson, Christina M. J. E. Vandenbroucke-Grauls,Nicole N. van der Wel, Tom H. M. Ottenhoff, and Wilbert Bitter

Inflammation7176 TLR/MyD88 and Liver X Receptor � Signaling Pathways Reciprocally Control

Chlamydia pneumoniae-Induced Acceleration of AtherosclerosisYoshikazu Naiki, Rosalinda Sorrentino, Michelle H. Wong, Kathrin S. Michelsen, Kenichi Shimada, Shuang Chen,Atilla Yilmaz, Anatoly Slepenkin, Nicolas W. J. Schroder, Timothy R. Crother, Yonca Bulut, Terence M. Doherty,Michelle Bradley, Zory Shaposhnik, Ellena M. Peterson, Peter Tontonoz, Prediman K. Shah, and Moshe Arditi

7186 Chlamydia pneumoniae-Induced Foam Cell Formation Requires MyD88-Dependent and -IndependentSignaling and Is Reciprocally Modulated by Liver X Receptor ActivationShuang Chen, Rosalinda Sorrentino, Kenichi Shimada, Yonca Bulut, Terence M. Doherty, Timothy R. Crother,and Moshe Arditi

7194 Macrophage Antigen Complex-1 Mediates Reactive Microgliosis and Progressive DopaminergicNeurodegeneration in the MPTP Model of Parkinson’s DiseaseXiaoming Hu, Dan Zhang, Hao Pang, W. Michael Caudle, Yachen Li, Huiming Gao, Yuxin Liu, Li Qian,Belinda Wilson, Donato A. Di Monte, Syed F. Ali, Jing Zhang, Michelle L. Block, and Jau-Shyong Hong

7205 Phenotype Switching by Inflammation-Inducing Polarized Th17 Cells, but Not by Th1 CellsGuangpu Shi, Catherine A. Cox, Barbara P. Vistica, Cuiyan Tan, Eric F. Wawrousek, and Igal Gery

7214 IL-10 and TGF-� Redundantly Protect against Severe Liver Injury and Mortality during AcuteSchistosomiasisDe’Broski R. Herbert, Tatyana Orekov, Charles Perkins, and Fred D. Finkelman

7221 CD4�CD25� Foxp3� Regulatory T Cells Protect against T Cell-Mediated Fulminant Hepatitis in aTGF-�-Dependent Manner in MiceHua-Xing Wei, Ya-Hui Chuang, Bofeng Li, Haiming Wei, Rui Sun, Yuki Moritoki, M. Eric Gershwin, Zhe-Xiong Lian,and Zhigang Tian

7230 Dendritic Cells Genetically Engineered to Express IL-10 Induce Long-Lasting Antigen-Specific Tolerancein Experimental AsthmaEmmanuelle Henry, Christophe J. Desmet, Virginie Garze, Laurence Fievez, Denis Bedoret, Carlo Heirman, Pedro Faisca,Fabrice J. Jaspar, Philippe Gosset, Alain P. A. Jacquet, Daniel Desmecht, Kris Thielemans, Pierre Lekeux, Muriel Moser,and Fabrice Bureau

7243 Mechanisms of Oncostatin M-Induced Pulmonary Inflammation and FibrosisAfsaneh Mozaffarian, Avery W. Brewer, Esther S. Trueblood, Irina G. Luzina, Nevins W. Todd, Sergei P. Atamas,and Heather A. Arnett

7254 Fibrillar Amyloid-� Peptides Activate Microglia via TLR2: Implications for Alzheimer’s DiseaseMalabendu Jana, Carlos A. Palencia, and Kalipada Pahan

7263 TGF-�1 Attenuates Mediator Release and De Novo Kit Expression by Human Skin Mast Cells through aSmad-Dependent PathwayWei Zhao, Gregorio Gomez, Shao-Hua Yu, John J. Ryan, and Lawrence B. Schwartz

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7273 Prostaglandin E2 Inhibits Eosinophil Trafficking through E-Prostanoid 2 ReceptorsEva M. Sturm, Petra Schratl, Rufina Schuligoi, Viktoria Konya, Gunter J. Sturm, Irmgard Th. Lippe, Bernhard A. Peskar,and Akos Heinemann

7284 NF-�B-Driven STAT2 and CCL2 Expression in Astrocytes in Response to Brain InjuryReza Khorooshi, Alicia A. Babcock, and Trevor Owens

7292 Pleural Mesothelial Cells Express Both BLT2 and PPAR� and Mount an Integrated Response to PleuralLeukotriene B4Elisabetta Pace, Maria Ferraro, Christopher H. Mody, Mario R. Melis, Valeria Scafidi, Anna Bonanno, Mirella Profita,Antonino Giarratano, and Mark Gjomarkaj

7300 The Effect of the JNK Inhibitor, JIP Peptide, on Human T Lymphocyte Proliferation andCytokine ProductionMichelle Melino, Charles S. Hii, Shaun R. McColl, and Antonio Ferrante

7307 A New Mechanism for Inhalational Priming: IL-4 Bypasses Innate Immune SignalsAnna M. Dittrich, Hui-Chen Chen, Lan Xu, Patricia Ranney, Sean Connolly, Timur O. Yarovinsky,and H. Kim Bottomly

7316 Dual Regulatory Roles of Phosphatidylinositol 3-Kinase in IFN SignalingSurinder Kaur, Antonella Sassano, Ajith M. Joseph, Beata Majchrzak-Kita, Elizabeth A. Eklund, Amit Verma,Saskia M. Brachmann, Eleanor N. Fish, and Leonidas C. Platanias

7324 Active Caspase-1-Mediated Secretion of Retinoic Acid Inducible Gene-IMin-Jung Kim and Joo-Yeon Yoo

7332 Induction of Scavenger Receptor Class B Type I Is Critical for Simvastatin Enhancement of High-DensityLipoprotein-Induced Anti-Inflammatory Actions in Endothelial CellsTakao Kimura, Chihiro Mogi, Hideaki Tomura, Atsushi Kuwabara, Doon-Soon Im, Koichi Sato, Hitoshi Kurose,Masami Murakami, and Fumikazu Okajima

7341 Oncostatin M-Induced and Constitutive Activation of the JAK2/STAT5/CIS Pathway Suppresses CCL1,but Not CCL7 and CCL8, Chemokine ExpressionChristoph Hintzen, Claude Haan, Jan P. Tuckermann, Peter C. Heinrich, and Heike M. Hermanns

Clinical Immunology7350 The Effector T Cells of Diabetic Subjects Are Resistant to Regulation via CD4�FOXP3� Regulatory

T CellsAnya Schneider, Mary Rieck, Srinath Sanda, Catherine Pihoker, Carla Greenbaum, and Jane H. Buckner

7356 Measles Virus Infection in Adults Induces Production of IL-10 and Is Associated with IncreasedCD4�CD25� Regulatory T CellsXue-lian Yu, Yu-ming Cheng, Bi-sheng Shi, Fang-xing Qian, Feng-bin Wang, Xi-nian Liu, Hai-ying Yang, Qing-nian Xu,Tang-kai Qi, Li-jun Zha, Zheng-hong Yuan, and Reena Ghildyal

7367 Sunlight Triggers Cutaneous Lupus through a CSF-1-Dependent Mechanism in MRL-Faslpr MiceJulia Menke, Mei-Yu Hsu, Katelyn T. Byrne, Julie A. Lucas, Whitney A. Rabacal, Byron P. Croker, Xiao-Hua Zong,E. Richard Stanley, and Vicki R. Kelley

7380 Breaking of CD8� T Cell Tolerance through In Vivo Ligation of CD40 Results in Inhibition of ChronicGraft-versus-Host Disease and Complete Donor Cell EngraftmentJuyang Kim, Keunhee Park, Hyun J. Kim, Jiyoung Kim, Hyun-A Kim, Daehee Jung, Hye J. Kim, Hye-Jeong Choi,Suck-Young Choi, Kwang W. Seo, Hong R. Cho, and Byungsuk Kwon

7390 Intestinal Macrophage/Epithelial Cell-Derived CCL11/Eotaxin-1 Mediates Eosinophil Recruitment andFunction in Pediatric Ulcerative ColitisRichard Ahrens, Amanda Waddell, Luqman Seidu, Carine Blanchard, Rebecca Carey, Elizabeth Forbes, Maria Lampinen,Tara Wilson, Elizabeth Cohen, Keith Stringer, Edgar Ballard, Ariel Munitz, Huan Xu, Nancy Lee, James J. Lee,Marc E. Rothenberg, Lee Denson, and Simon P. Hogan

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7400 Telomerase-Based Pharmacologic Enhancement of Antiviral Function of Human CD8� T LymphocytesSteven Russell Fauce, Beth D. Jamieson, Allison C. Chin, Ronald T. Mitsuyasu, Stan T. Parish, Hwee L. Ng,Christina M. Ramirez Kitchen, Otto O. Yang, Calvin B. Harley, and Rita B. Effros

7407 Multiple Glycines in TCR �-Chains Determine Clonally Diverse Nature of Human T Cell Memory toInfluenza A VirusYuri N. Naumov, Elena N. Naumova, Maryam B. Yassai, Kalyani Kota, Raymond M. Welsh, and Liisa K. Selin

7420 Low Expression of the IL-23/Th17 Pathway in Atopic Dermatitis Compared to PsoriasisEmma Guttman-Yassky, Michelle A. Lowes, Judilyn Fuentes-Duculan, Lisa C. Zaba, Irma Cardinale, Kristine E. Nograles,Artemis Khatcherian, Inna Novitskaya, John A. Carucci, Reuven Bergman, and James G. Krueger

7428 CORRECTIONS

7429 AUTHOR INDEX

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