synthetic biology present & future a view from genopole françois képès & françoise...
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Synthetic Biology present & futurea view from Genopole
François Képès & Françoise Russo-Marie
Bruxelles BiologyWorkshop 180310
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Genopole, a Bio-Park created in 1998with 2 missions
To promote Research in genetics, genomics and post genomics.
To implement a Technopole fosteringcreation and development of biotechnology companies.
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Genopole, N° 1 French Bio-Park
The score so far1997 2008
• Academic Laboratories (933 employees) 2 20• Biotech Companies (1023 employees) 3 69• Large scale facilities 0 19• Funds raised by Companies (M€) 0 208• Total headcount Direct 411 2293
Indirect 1000 6000• Molecules or biotherapies ongoingpreclinical & clinical trials
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• Real estate offer (m2) 19000 872983Bruxelles Biology Workshop 180310
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Our mission
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Our partners
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• National Sequencing Center• National Genotyping Center• Genethon (Gene therapy)
Genoplante Program (Inra)
Rely on Genomics centers
Rely on strong academic partnerships• UEVE (University), CNRS, CEA, INSERM, INRA (4 research institutes)
Extend the partnerships when appropriate (PSEVS)
TMSP, ENSMP, ENSIIE (3 engineers schools: IT, Materials, Electronics, Management)
CHSF: the Hospital (1000 beds)
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Genopole science & Major programmes
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Systems & Synthetic Biology (SSB)
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Partners: France: Évry, Bordeaux, Montpellier, Brest, Rouen, Nice, Lyon, Grenoble, Orsay, Paris, Foreign: UK, Spain, Belgium, …
Epigenomics Project:2000: Inception & cooperation with IHÉS2003: Physical space2006: Increased operations and space2010: Move in new building, pending Genopole® funding
Activities: Research Network(9 virtual laboratories)
Visitor’s ProgrammeScientific Events Programme
(~75 effective days per year)
Genopole® Evry, FranceScientific animation and networking
Scientific Director: François Kepes (CNRS)Scientific Adjunct Directors: Vic Norris (Univ Rouen); Gilles Bernot (Univ Nice)
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Coupling analytics and synthetics
Exploration Exploitation
Analytics Synthetics
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The partners for iSSB
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Systems & Synthetic Biology (SSB)
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Genopole® Evry, FranceMaster 2 in Systems & Synthetic Biology
2010: Opening
Partners: PRES UniverSud Paris: ECP, AgroParisTech; Telecom Sud Paris
Europe: Negotiations with European partners
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Systems & Synthetic Biology (SSB)
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Teams: Subdisciplines
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Teams: Objectives
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The research teams
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Systems & Synthetic Biology (SSB)
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The core facilities
CONCEPTIONComputational calculationWeb site and softwares
CONCEPTIONComputational calculationWeb site and softwares
CONSTRUCTIONMolecular biology: Robotized platform
CONSTRUCTIONMolecular biology: Robotized platform
CHARACTERISATIONmicrofluidicsExpression analysis(gene – proteins –metabolites)
CHARACTERISATIONmicrofluidicsExpression analysis(gene – proteins –metabolites)
CUSTOMER SERVICECUSTOMER SERVICE
SU
PP
OR
TS
LIMSLIMS
BIOLOGICAL RESOURCE CENTERBIOLOGICAL RESOURCE CENTER
DATA BASEDATA BASE
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Systems & Synthetic Biology (SSB)
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The SME/Biotech
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Synthetic Biology present & future ???
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» This paper was produced for a meeting organized by Health & Consumers DG and
represents the views of its author on the subject. These views have not been
adopted or in any way approved by the Commission and should not be relied upon
as a statement of the Commission's or Health & Consumers DG's views. The
European Commission does not guarantee the accuracy of the data included in
this paper, nor does it accept responsibility for any use made thereof.