“surfing the pipeline” - bizint solutions - bizint ...€¦ · citeline pharmaprojects 29% adis...

BizInt Smart Charts 2014 1

Pharma-Bio-Med, Rome November 2014 Diane Webb, President

“Surfing the Pipeline” Comparing Drug Pipeline Database Coverage and Content


Ten Techniques to Visualize Clinical Trials


BizInt Smart Charts Product Family

Provides corporate information analysts with software tools to create reports and visualizations integrating information from their key sources.


“Cookbook” of techniques

• The Cookbook contains a collection of recipes to help you create accurate and appealing products from your raw ingredients.

• Step-by-step recipes illustrate how each tool can be used.

• Substitute ingredients as needed to answer your business questions.


Drug Pipeline Databases Provide data on drugs in development worldwide

• Citeline Pharmaprojects • IMS R&D Focus • Adis R&D Insight • Thomson Reuters Cortellis • Thomson Reuters Integrity Slides at www.bizint.com/slides


Case study: Hepatitis C Pipeline

Query: indication = Hepatitis C, all phases (exact query differs by database)

Records retrieved: Cortellis: 777 Integrity: 359 Pharmaprojects: 689 R&D Focus: 420 R&D Insight: 474 Import search results and use File|Combine

to create a single multi-database chart


Identify related records across databases

*

Tools | Generate Common Drug Name identifies records for the same drug by matching drug names and synonyms.


25%

15%

17%

29%

13%

45%

27%

31%

51%

23%

0% 10% 20% 30% 40% 50% 60%

Citeline Pharmaprojects

IMS R&D Focus

Adis R&D Insight

Thomson Reuters Cortellis

Thomson Reuters Integrity

% of Drugs vs. Records Retrieved from each Database (Indication = Hepatitis C)

% of Drugs (Total of all DBs)

% of All Records Retrieved

Database Coverage Analysis

* Drugs (Total of all DBs) identified using the “Generate Common Drug Name” tool.

*


Thomson Reuters Cortellis

35%

Citeline Pharmaprojects

29%

Adis R&D Insight 15%

IMS R&D Focus 17%

Thomson Reuters Integrity

Compounds 4%

Distribution of drugs found in a single database


Database Coverage by Phase (records)

64

182 127

194

93

92

113

114

127

171 64

25

49

102

52 84

100 149

144

43

385 35

210

0

100

200

300

400

500

600

700

800

All All All All All

Pharmaprojects R&D Focus R&D Insight Cortellis Integrity

# of Records by Highest Phase (for all indications )

No Dev Rep

Discontinued

Launched

Clinical

Discovery


Highest phase for indication of interest

We know the “Highest Phase” for all indications, but the phase for our indication of interest (Hep-C) is buried in the Drug Development Phase table.


Extracting the highest phase for Hep-C

Export to VantagePoint-Smart Charts Edition


Extracting the highest phase for Hep-C

Need to filter and clean-up indications.


Extracting highest phase for Hepatitis-C

Cleanup Hep-C indication



Filter the Drug Development Phase table to include only

the Hepatitis C entries.



Export to BizInt Smart Charts as a new column.


64 65

182 159 127 117 194 195

93 100

92 82

113 110

114 110

127 124

171 184 64 52

25 20 49

38

102 84

52 31 84

85

100 97

149 163

144 113

43 43

385 405 35 46

210 261

0

100

200

300

400

500

600

700

800

All Hep C All Hep C All Hep C All Hep C All Hep C


# of Records by Phase (for all indications and Hepatitis C)

No Dev Rep

Discontinued

Launched

Clinical

Discovery

Database Coverage by Phase (# of records)


Database Coverage by Phase (%)

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

All Hep C All Hep C All Hep C All Hep C All Hep C


Distribution of Records by Phase (for all indications and Hepatitis C)

No Dev Rep

Discontinued

Launched

Clinical

Discovery


Summarize differences between databases



Create a summary table with database, phase and

update date



Apply the “Summarize All Values” rule to the new

summary table


Analyze differences in phases (hep-c vs all)

Use “Compare Columns” to find drugs with different phase for Hep-C than for all indications



Create a Bubble Graph in VP-SCE to spot trends



Create a Bubble Graph in VP-SCE to spot trends

Marketed Drugs in Phase 2 for Hepatitis C


“Surfing the Pipeline” - conclusions

Pipeline databases continue to vary in coverage and content.

The more pipeline databases you use, the better you can exploit the strengths of each.

BizInt Smart Charts tools can help you aggregate, summarize and visualize multi-database pipeline information…

…to create more accurate and effective pipeline intelligence!


Visit our stand for more info and to see the

Cookbook!

www.bizint.com

“surfing the pipeline” - bizint solutions - bizint ...€¦ · citeline pharmaprojects 29% adis...

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