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supplementary figure 1lewis, et al

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Supplementary Figure 1 Lewis, et al. a b Dacetuzumab (soluble) Dacetuzumab (crosslinked) 1 3 10 1 3 10 10 10 20 Untreated hIgG (soluble) hIgG (crosslinked) Crosslinking Ab CD40 Ligand g/ml phospho-AKT phospho-ERK1/2 MAPK IB- phospho-p38 MAPK Lane: 1 2 3 4 5 6 7 8 9 10 11 1 Untreated hIgG (crosslinked) Dacetuzumab (soluble) Dacetuzumab (crosslinked) Cell Death (Ramos) Percent Cell Death (apoptotic + necrotic) Dacetuzumab (crosslinked) Proliferation (Ramos) ng/ml Dacetuzumab Signaling (RL) phospho-ERK1/2 MAPK -Actin 1 11 ng/ml Dacetuzumab Untreated 33 3 1 .00x10 3 3 7.0 1 2.3 4 .12 Ramos c

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Cell Death (Ramos). Untreated. Proliferation (Ramos). hIgG (crosslinked). Dacetuzumab (soluble). Dacetuzumab (crosslinked). Percent Cell Death (apoptotic + necrotic). Crosslinking Ab. Dacetuzumab (soluble). hIgG (crosslinked). Dacetuzumab (crosslinked). CD40 Ligand. - PowerPoint PPT Presentation

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Page 1: Supplementary Figure 1Lewis, et al

Supplementary Figure 1 Lewis, et al.

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