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Supplementary Fig.1 0.0 2.0 4.0 6.0 8.0 10.0 12.0 14.0 DAOY D 458 M ed M ed8A NCB miR-182 miR-183 Native expression Relative expression ratio vs. HKsRNAs a 0 10 20 30 40 50 60 70 Relative expression ratio vs. pCMX DAOY Med8A Relative expression ratio vs. pCMX Stable overexpression b 0 20 40 60 80 100 120 140 D458 Med Relative expression ratio vs. pCMX 0 1 2 3 4 5 6 7 8 pC M X 182K 1 182K 2 183K 1 183K 2

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b. Relative expression ratio vs. pCMX. DAOY. Relative expression ratio vs. pCMX. D458 Med. Relative expression ratio vs. pCMX. Med8A. Stable overexpression. Supplementary Fig.1. a. Relative expression ratio vs. HKsRNAs. Native expression. c. Relative expression ratio vs. siCtrl. - PowerPoint PPT Presentation

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Page 1: Supplementary Fig.1

Supplementary Fig.1

0.02.04.06.08.0

10.012.014.0

DAOY D458Med

Med8A NCB

miR-182

miR-183

Native expression

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s. H

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sa

0

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40

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pCMX 182K1 182K2 183K1 183K2

Re

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CM

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8AR

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Stable overexpression

b

0

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80

100

120

140

pCMX 182K1 182K2 183K1 183K2

D45

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pCMX 182K1 182K2 183K1 183K2

Page 2: Supplementary Fig.1

Supplementary Fig.1

0.0

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siCtrl si182 siCtrl si183

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siCtrl si182 siCtrl si183

Page 3: Supplementary Fig.1

Supplementary Fig.2

Page 4: Supplementary Fig.1

Supplementary Fig.3

Page 5: Supplementary Fig.1

Molecular subgroup

miR-182 miR-183 miR-96

Supplementary Fig.4

Page 6: Supplementary Fig.1

Supplementary Fig. 5

Page 7: Supplementary Fig.1

Transient knockdown

0.5

1.0

1.5

2.0

2.5

3.0

3.5

1 2 3 4 5 6 7

DAOY-siCtrlDAOY-si183

DAOY-si182

0.5

1.0

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M8A-siCtrl

M8A-si183

M8A-si182

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DAOY-pCMX

DAOY-183K1

DAOY-183K2

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DAOY-pCMX

DAOY-182K1

DAOY-182K2

0.51.01.52.02.53.03.54.04.55.0

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M8A-pCMXM8A-183K1M8A-183K2

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Supplementary Fig. 6


Supplementary Fig 1

Supplementary Fig. 7 · Supplementary Fig. 7. Supplementary Figure 7. Gating strategy for immune profile analyses in this study. Created Date: 11/7/2019 4:04:58 PM

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Supplementary Fig. S7

Fig. 1 ( Supplementary data)

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Supplementary Fig . 1

Supplementary Fig. S1

Supplementary Fig. 3

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Supplementary Fig. S1 A.B.. A. Supplementary Fig. S2 B. C

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