supervised by : dr. adham abutaha presented by : razan abd al-nabi
TRANSCRIPT
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MOXEZASupervised by : Dr. Adham AbutahaPresented by : Razan Abd Al-Nabi
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• Overview• Mechanism of action• Usage and indication• Dosage and administration• Precautions and important
information• Side effects• Moxeza vs. other medications
OUTLINE:
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• Generic Name: moxifloxacin ophthalmic• Active Ingredient: moxifloxacin hydrochloride• Company: Alcon, Inc• Date of Approval: November 19, 2010• Treatment for: Bacterial Conjunctivitis
Bacterial Conjunctivitis A bacterial infection of a portion of the eye
known as the conjunctiva . Common symptoms include redness
of the eyeswith a thick, often coloured purulent discharge.
OVERVIEW:
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MOA: Moxifloxacin is a member of the
fluoroquinolone class of anti-infective drugs.
it inhibits the topoisomerase II (DNA gyrase) and topoisomerase IV.
(g)-
(g+)
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USAGE & INDICATION
• Moxeza solution is a topical fluoroquinolone anti-infective indicated for the treatment of conjunctivitis caused by susceptible strains of the following organisms:
Aerococcus viridans, Corynebacterium macginleyi, Enterococcus faecalis, Micrococcus luteus, Staphylococcus sp., Streptococcus sp., Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Propionibacterium acnes, Chlamydia trachomatis
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• Off-lable uses - to treat bacterial eye infections other
than conjunctivitis - to prevent any type of eye infection,
such as a post-surgical eye infection.
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:DOSAGE & ADMINISTRATION
• Instill 1 drop in the affected eye(s) 2 times daily for 7 days
Apply light pressure to the inside corner of the eye (near the nose) after each drop to prevent the fluid from draining down the tear duct
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PRECAUTIONS AND IMPORTANT INFORMATION:• It is used to treat infections caused by
bacteria only. Do not use Moxeza if you have had an allergic reaction to it or other similar medicines in the past
• Do not use other eye drops or medications during treatment with Moxeza unless otherwise directed by your doctor.
cont.
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• If you wear contact lenses, remove them before applying Moxeza. Ask your doctor if contact lenses can be reinserted after application of the medication
• Moxifloxacin ophthalmic should only be used during pregnancy when benefit outweighs risk.
• Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye
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MOXEZA SIDE EFFECTS:
• Serious side effects are not expected to occur during treatment with this medication.
• Some eye burning ,irritation ,fever ; or blurred vision may occur.
Use caution when driving, operating machinery, or performing other hazardous activities
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MOXEZA VS. OTHER MEDICATIONS
• Vigamox® is an older version of the same medication.However,Moxeza…
- is formulated differently - only has to be used twice a day - is approved for treating bacterial
conjunctivitis in children as young as four months old• Other antibiotics…• Other dosage forms…
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THANKS