sugar shifting: optimising food systems resilience in...
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Sugar Shifting:
Optimising Food Systems Resilience In Transition to Low Sugar Consumption
A multi-actor workshop held March 13, 2017 at the University of Leeds
Dr. J. Bernadette Moore
Associate Professor of Obesity
N8 Pump Priming Presentation
University of Leeds, February 15, 2018
What are the dietary, genetic and molecular factors that influence NAFLD pathogenesis?
Moore, Maldonado In preparation
Proteomics and Multi-scale Modelling of Hepatic Lipogenesis
Fisher et al. (2013) Bioinformatics
Fisher et al. (2014) World J Gastroenterology
Spanos & Moore (2016) Methods in Molecular Biology
Maldonado et al. (2017) CPT: Pharmacometrics & Systems Pharmacology
Spanos, Maldonado, Fisher et al. (2018) Proteome Sciences
Maldonado, Fisher et al. Invited to revise & resubmit, NPJ Systems Biology & Applications
Scrutinized because:
• Intakes have risen in parallel with obesity
• Metabolized differently by liver• At high experimental doses
exacerbates obesity and NAFLD
BUT
• Experimental doses far exceed what we consume
• Rarely consume single sugar in isolation
• When excess energy controlled for no differential effect
Fructose:
The New F Word
Moore et al. (2014) Nutrients
Moore & Fielding B (2016) Curr Opin Clin Nutr Metab Care
Obesity & Sugar Consumption
OECD Obesity Update 2014: www.oecd.org/health/obesity-update.htm
RJ Johnson et al. 2007 Am Soc Clin Nutr
Moore & Fielding (2016) Curr Opin Clin Nutr Metab Care
Evidence
• Causal link between high-sugar diet and obesity and dental caries
• The role of sugar-sweetened beverage consumption in development of
diabetes
Recent Guidelines from UK, US, WHO Unanimously Recommend Cutting Consumption of Added Sugars
Childhood Obesity
• 42 million children under the age of 5 were overweight or obese in 2013.
Lobstein et al (2015) Lancet 385: 2510–20
‘Obesity is preventable.’
- WHO
25.0%24.2%
22.7%21.2%
19.3%17.8%
16.0%15.0%
13.7%
11.5%12.0%11.2%
10.3% 9.7%9.0%
8.3% 7.6% 7.0% 6.8%5.7%
0%
5%
10%
15%
20%
25%
30%
Mostdeprived
Leastdeprived
Ob
esit
y p
reva
len
ce
Index of Multiple Deprivation 2010 decile
Year 6
Reception
Child obesity: BMI ≥ 95th centile of the UK90 growth reference
National Child Measurement Programme 2014/15
Increase in LocalInterventions
Brighton & Hove
(University of Brighton)
Bristol
Lewisham
Greenwich
Exeter
FRC Policy Briefs, 2015
‘a better food system would begin to wean the
world off massive sugar production and
consumption’
‘surely, more attention ought to be given to
chart a better form of employment and land
use; better health and environment’
‘If consumption falls to 5% likely to impact ACP’
Sugar Shifting:
Optimising UK Food Systems Resilience in
Transition to Low Sugar Consumption
O5: Multi-actor
Stakeholder Engagement
Knowledge Exchange
Consumers Producers
O1: Household
Purchasing
O2: Determinants of
Food Choice
O3: Environmental
Impacts
O4: Producer
Communities
Industries Policymakers
Multi-actor workshop: Nutrition, public health, consumer behaviour, environmental sustainability and the political economy
Sugar Shifting:
Optimising UK Food Systems Resilience in
Transition to Low Sugar Consumption
March 13th, University of Leeds