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Sudden Cardiac Death Syndrome Alexis Cortez-Bautista University of California, Merced

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Sudden Cardiac Death Syndrome. Alexis Cortez-Bautista University of California, Merced. What is SCD?. SCD has a broad definition depending on who is studying it. Who does it affect. - PowerPoint PPT Presentation

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Page 1: Sudden Cardiac Death Syndrome

Sudden Cardiac Death Syndrome

Alexis Cortez-BautistaUniversity of California, Merced

Page 2: Sudden Cardiac Death Syndrome

SCD has a broad definition depending on who is studying it

What is SCD?

Page 3: Sudden Cardiac Death Syndrome

Anyone can be affected by this disorder and is most of the time unexpected, however a group that has seem to be commonly affected is Athletes and active healthy people

Who does it affect

Page 4: Sudden Cardiac Death Syndrome

Studies have shown that there are many risk factors that may contribute to Sudden Cardiac Death including◦ Congenital heart disease◦ Mutations in SQTS genes◦ Epilepsy

Risk Factors

Page 5: Sudden Cardiac Death Syndrome

Hamilton, Leslie E., Lew,Emma O., Matshes, Evan W. (2011) ‘‘Grown-Up’’ Congenital Heart Disease and Sudden Death in a Medical Examiner’s Population. Journal of Forensic

Sciences. 56:1206-1213 Koyak, Zeliha. Harris, Louise,. de Groot,,Joris R.,

Silversides, Candice K., Oechslin,Erwin N., Bouma, Berto J., Budts, Werner., Zwinderman, Aeilko H., Van Gelder, Isabelle C., Mulder, Barbara J.M.(2012). Sudden Cardiac Death in Adult Congenital Heart Disease.Circulation. 1944-1954.

Congenital Heart Disease

Page 6: Sudden Cardiac Death Syndrome

Lahtinen, Annukka M., Noseworthy , Peter A., Havulinna, Aki S., Jula, Antti , Pekka J. Karhunen, Kettunen, Johannes, Perola, Markus., Kontula, Kimmo, Newton-Cheh, Christopher.,Salomaa, Veikko. Common Genetic Variants Associated with Sudden Cardiac Death: The FinSCDgen Study. PLOS ONE. 7.7:1-7

Wisten, Aase., Bostrom, Ida Maria., Morner, Stellan., Stattin, Eva Lenna. (2012) Mutation analysis of cases of sudden unexplained death, 15 years after death:Prompt genetic evaluation after resuscitation can save future lives. Resuscitation. 83:1129-1234

Mutations

Page 7: Sudden Cardiac Death Syndrome

Bardai, Abdennasser., Lamberts, Robert J., Blom, Marieke., Spanjaart, Anne M., Berdowski Jocelyn., van der Staal, Sebastiaan R., Brouwer, Henk J., Koster, Rudolph W., Sander, Josemir W., Thijs Roland D., Hanno L. Tan. (2012) Epilepsy Is a Risk Factor for Sudden Cardiac Arrest in the General Population. Plos one. 7.8:1-5

Epilepsy

Page 8: Sudden Cardiac Death Syndrome

Because this disorder is so spontaneous, the most common approach to study this disorder is through retrospective observations

There might be an advantage to performing research on people with the risk factors

Approaches

Page 9: Sudden Cardiac Death Syndrome

Screenings using ECG have the potential to identify changes in the heart that could lead to SCD

Screenings

Page 10: Sudden Cardiac Death Syndrome

Questions


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