A

Abnormalitics in thc Ultrastructurc of Melanocytes and the O uter Root Sheath of C linicaUy Normal Hair Follicles from Alopecia Areata Scalps. Nutbrown M, MacDonald Hull SP, Cunliffe WJ, RandaU VA,12S

Abstracts for Society of Investigative Dermatology, 554 Acetylcholine receptors. keratinocyte. muscarinic, 95 Acid (s)

arachidonic, 52 eicosatrienoic, 47 fatty

oxygenases. epidenna.!, 25 1 polyunsaturated. cnrichment. 964 synthetic enzyme activity in mouse epidernlis, 401

retinoic in cultured human skin fibrob lasts, 503 ora l epithe lial differentiation regulation, 224 receptor gamma, 779

Ac idic Fibroblast Growth Factor Acceleratcs Demlal Wound Healing in D iabctic Micc, Mellin TN, Cashen DE, R onan JJ. Murphy BS, DiSalvo J. T homas KA, 850

Activated gelatinases . 236 Activated Mast Cells Are Fibrogenic for 3T3 Fibroblasts, Levi-Schaffer F,

Rubinchik E, 999 Adaptive responses in the skin, 448 Adcnosine and Adenine Nucleotides Inhibit the Autonomous and Epider­

mal Growth Factor-Mediatcd Proliferation of C ul tured Human Keratinocytes. Cook PW, Ashton NM, Pittelkow MR, 976

Adenoviral-mcdiated HSV thymid ine kinase gene transfcr i" ,,;vo, 313 Adhere.lS junction, 27 Adhesion molecule(s)

1 interceUular

interferony-induccd, inhibi tion of. 813 involvcmcnt of granulocytes and. 350 on human epidermal Langerhans ccll s, 995 rcceptors, 350

kcrati nocytc- keratinocyte interactions.146 11. 1008

Adhesion Molecules. I: Keratinocyte-Keratinocyte Intcractions: Cadherins and Pcmphigus, Amagai M, 146

Adhesion Molecules II : In teractions of Ker"tinocytes with EpidemlaJ Base­ment Membranc. Yancey K13. 1008

Adult melanocytes, human, 755 Agonist-Induccd Exprcssion of T issue Inhibitor of Metalloprotcinases and

Metalloproteinases by Human Macrophages Is Regulated by Endo­genous Prostagland in E, Synthesis, Pcntland AP, Shapiro SO, Wel­gus HG. 52

AHN AKI desmoyokin protein. 941 Allele(s)

HLA class II. 4S HLA-D locus. 5S of the intcrleuki n-1 reccptor antagonist, 15S

Allele of the Interlcukin-l Reccptor Antagonist as a Genctic Sevcrity Factor in Alopecia Areata. An, Cork MJ, Tarlow JK, C lay FE, Crane A. Blakcmore AIF, M cDonagh AJ G, Messenger AG. D uff GW. 15S

Alopecia arcata

C3H/HeJ mouse model for, 16S clinically normal hair fo lliclcs from scalps of paticnts with , 12S cutancous nerves in, 28S cytokinc patterns in , 14S dermal papilla function in. 7S. 9S gcnetic severity f.1ctor in, 15S glucocorticoid regulation of hair grow til in. 30S hair follicles , 18S histopathology of. 26S HLA-O locus allelcs in . 5S

SUBJECT AND TITLE INDEX FOR VOLUME 104

humans, in. 32S immunity to hair follicles in , 13S immunologic cytotoxicity in, 8S mammals. in. 32S molecular approach to. 3S patchy, 4S research workshop summary, 2S severe, 36S sera, 25S T-cell receptor reperto ire V {3 in. 22S thymus gland in , 25S topical immunotherapy in children with. 35S trachyonychia in , 27S

totalis, 4S wuversalis, 4S

Alopecia Areata in Humans and Other Mammalian Species. Sundberg JP. Oliver RF, McElwee KJ, King LE Jr, 32S

a , {3, integrin function, 768 a6{34 integrin complex, 266 Alteration in Cell Morphology Triggers Transfooning Growth Factor-{31,

Collage nase, and Tissue Inhibitor of Metalloproteases-I E.xpression in Normal and Hypertropluc Scar Fibroblasts. Varedi M, Tredget EE, Scott PG, Shcn YJ, Ghallary A. 118

Altered Immunolustochemical Expression of Small Proteoglycans in the Tumor Tissue and Strom a of Basal Cell Carcinoma, Hunzelmann N. Sch6nherr E, Bonnekoh B, Hartmann C. Kresse H, Krieg T. 509

Altered Laminin 5 Exp· .. ession Due to Mutations in the Gene Encoding the {33 Chain (Lamb3) In Generalized Atrophic Benign Epideonolysis Bullosa, McGrath JA , Pulkkinen L, C hristiano AM, Leigh 1M. Eady RAJ , Uitto J , 467

Amelanotic melanocyte. 86 Amelioration of the Metabolic Defect in Erytluopoietic Protoporphyria by

Express ion of Human Ferrochelatase in C ultured Cells, Mathews­Roth MM, Michel JL, Wise Rj. 497

Amiloride, 38 Amino-terminus of human profilaggrin. calcium-binding sites in. 218 Anagen

hair follicle. 90, 42S induction i" telogen mouse skin. 523

Analysis of Gene Expression in Isolated Single Hair Follicles: An Approach Using Scmiquantitativc Reverse-Transcriptase-Polyacrylamide Chain Rcaction. Hofli'lann R. Happle R. 20S

Analysis of HLA-D Locus Alleles in Alopecia Arcata Patients and Families, Duvic M. Welsh EA,Jackow C. Papadopoulos E, ReveilleJD, Amos C,5S

A.uon. superoxide, production. 789 Anthralin-derivcd free radicals. 514 Antibodies

against cultured autologous melanocytes. none found. 24S granulocytc macrophag{.~ colony-stimulatiJlg factor, to, 335 pathogenic in pemphigus foliaceus, 895 proteins E4, E6, E7, to. 138

Antibodies to tl,e E4, E6, and E7 Proteins of Human Papilloma virus (HPV) Typc 16 in Patients with HPV-Associated Discases and in the Nonnal Population, Mullcr M, Viscidi RP. Vlken V. Bouwes BavinckJ N , Hill PM, Fisher SG, Reid R. Munoz N, Sclmeider A. Shah KV . Gissmann L. 138

Antigen(s) B7/BB-1, 763 Dsgl and Dsg3, 541 leucocyte, class II, human, 856 - 1. lymphocyte function-associated, 350 pcmp!ugus vu lgaris, 720 -presenting cells, 707 -spe~i fic immunoadsorption of parhogenic auto3Jltibodics in pemplugus

foliaceus, 895 T-, SV40 large. 755

0022-202X/95/S09.50 • Copyright © 1995 by The Society for Investigative Oeonatology. Inc.

1027

1028 SUBJECT AND TITLE INDEX

Antigen-Specific Immunoadsorption of Pathogenic Autoantibodies in Pem­phigus Foliaccus. Anlagai M. Hashimoto T, Green KJ. Slllmjzu N. NislUkawa T. 895 '

Antileukoproteinasc, (SKALP)/clafin, skin-derived. 189 Antioxidants. 484 AntiproLifcrative and Differentiative Activities of 1.25-Dihydroxyvitamin

D3 Are Potentiated by Epidermal Growth Factor and Attenuated by Insulin in Cultured Human Keratinocytes. The. C hen Te. Pcrsons K. Liu W-W. C hen ML. Holick MF. 113

Antisense o ligodeOl .... ynucleotides. phosphorothioate. 813 ApoLipoprotein E Deficiency Lcads to C utancous Foam Cell Formation in

Mice. Feingold KR. Eli as PM. Mao-Qiang M. Fartasch M. Zhang SH. Maeda N, 246

Apoptopic cell death. 526 Apoptosis

-associated genes in skin. exprcssion of, 78 of demlal papilla ccll s in alopecia areata. 8S of keratinocytes. 922 VVD-induced. 62

Appearance. Density. and Distribution of Mcrkcl Cells in Human Embry­onic and Fctal Skin: Thcir Relation to Sweat Gland and Hai.r Follicle Development. T he. Kim D-K, Holbrook KA, 411

Arachidonic acid. 52 Are People Who Get Skin Cancer Different? editorial. Kracmer KH. 887 Arginine, 438 Art and the Skin: A Salute to the Dystrophic Epidermolysis Bullosa

Research Association of Amcrica-Thc 15th ArUlivcrsary Cclebra­tion. "Closer to a C ure". Vitto J . 443

Association of Tumor Necrosis Factor-a Gene Expression and Apoptotic Cell Death w ith Regression of Shope Papillomas. Hagari Y. Bud­geon LR, Pickel MD. Krcider JW, 526

Athymic micc. 17'1. 345 Atrophic bcnign epidermolysis bullosa. 467 Autoantibodics

cicatricial pcmphigoid patients and. 370 pathogenic. 895 pcmphigus foLiace us and pcmphigus vulgaris. 323

Autoantibodies from Paticnts with Cicatricial Pemphigoid Target Different Sites in Epidemlal Basement Membrane. Shimizu H, Masunaga T. IslUko A. Matsumura K, Hashimoto T. Nishikawa T, Domloge­Hultsch N. Lazarova Z. Yancey KB. 370

Autoantigens. parancoplastic pemphigus. 829 Autocrine Down-Regulation of Basic Fibroblast Growth Factor Receptors

Causes Mitotoxin Res'istancc in a Human Melanoma Cell Linc. Davol p. BeitzJG. Frackclton AR Jr. 916

Autocpitopes. immunodominant. of type VlI collagen. 231 Autoimmwle disease. 146, lOS Autoimmune Diseases: Promising Emerging T herapies. Vanden bark AA.

lOS Autologous melanocytes. cul tured, 24S Axon-Reflex-Mediated Vasodilatation in thc Psoriatic Plaquc? Krogstad

AL. Swanbcck G. Wallin BG. 872

B

Barrier disruption. cutaneous permeability. 401 Basal cell carcinoma. 509. 928 Basement membrane, epidennal. 370, 1008 Basic fibrob last growth r.,ctor. 266 Benign atrophic epidemlolysis bullosa, 467 /31c;.:...H3. a Novel Secrctory Protein Induciblc by Transforming Growth

Factor-B. Is Prcsent in Normal Skin and Promotes the Adhcsion and Spreading of Dermal Fibroblasts III Vitro. LeBaron RG. Bczverkov Kl. Zimber MP. Pavclec R. Skonier J. Purchio AF, 844

/33 chain in atrophic bcnign epidermolysis bullosa. 467 Biglycan. 503 Biopsies, scalp, histopathology of alopecia arcata in . 26S Biphasic diacylglycerol production, induced. 835 Black hair follicles. 792 Blist~ring skin diseases, reepitheliaLization in . 982 Blood. antigen-presenting cells in . 707 Borrelia bllrgdoryeri-specific DNA. 23 Both Dendritic Cells and Memory T Lymphocytes Emigrate from Organ

Cultures of Human Skin and F0n11 Distinctive Dcndriti c- T-Cell Conjugates, Popc M. Beties MGH. Hinlland H. Hoffman L, Stein­man RM. 11

THE JOURNAL OF INVESTIGATIVE DERMATOLOGY

Brazilian pemphigus foliaceus. 541 Broad-band thcrapy sources. 359 B7IBB-1 antigcn. 763 Bullosa. epidermolysis

acq uisita. 231. atrophic benign. 467 dominant dystrophic. 438 B erLitz's junctional . 434. 462 pretibial. with li chenoid features. 803 recessivc dystrophic, 456 simplex-Weber-Cockayne. 877

Bullous pcmphigoid. 744 systemic lupus erythcmatosus. 231

Burn scar. hypertrophic. 750

c C,, ++ . extracellular, 768 Cadherin-mediatcd cell adhesion. disrupted classic. 27 Calcium

-binding sites in the amino-terminus of human profilaggrin, 218 intracellular. 33

Cancer. skin. 309. 883. 887 Carcinom a(s)

basal cell . 509. 928. 933 squamous ccll . linc. 33

Case of Pemphigus Vulgaris Showing Reactivity with Pcmphigus Antigcns (DsgJ and Dsg3) and Desmocollins. A. Hashimoto T. Anlagai M. Watanabe K. Dmochowski M. Chidgey MAJ . Yue KKM. Garrod DR. Nishikawa T. 541

Catagen. early. 78 Catecholamines in Human Keratinocytc Differentiation. Schallreutcr KU.

Lcm!<e KR,. Pittelkow MR. Wood JM . Korner C. Malik R. 953 Cathepsin D. 340 Cations Inhibit Specifically Type I 5a-Rcductase Found in Human Skin,

Sugimoto Y. L6pez-Solache I . Labrie F, Luu-The V. 775 CD50.995 Cell(s)

adhesion by a dominant negative mutant, 27 antigen-prescnting. 707 apoptopic, death. 526 basal. carcinoma . 509. 928. 933 cornified. envelopes, 391 -cycle kinetics, 755 defined populations, grafted onto nudc mice. 43S dendritic. 11 density. 271 dermal papilla in alopecia arcata, 8S DJM, 33 endothelioma. 824 cnvelope precursor protcins. cornified. 902 epidermal

am! dermal in skin grafts. 21 S dendritic. 287 Langerh:!ns, 995

epithelial culture. histiotypic. 989 sensitivity of to the cffects of methotrexate. 183

ferroche latasc in cultured. 497 foa m, cutancous, formation in mice. 246 human

dermal cndotheli ,.I . 101 skin. matrix-associatcd serine protease inhibitors from . 379

line, melanoma. human 916, lymphoid . 183 ' Langerhans

E-cadhcrin expression in . 293 murinc.329 subscts of phenotypic states in normal human epidermis. 42 transgenic class II major histocompatibility genes in murinc, 329

mast. 101, 999 Merkel

appearance, density and distribution. 411 cutaneous, 910

microvascular endothelial. hum'an. 266

VOL. 104. NO.6 J U NE 1995

mononuclear, 784 morphology, 11 8 squ3nlous, carCin01113 Ijne, 33 stem, hair fo lEcle, 38S sunburn, fonl1ation

involvement ofTNF-a, 922 UV-induced, 287 surface of human epidermis , non-desmosomal keratinocyte, 941

T -adherence to keratinocytes , inhibition by pentoxifylline, cutaneous lymphoma, 537, 824

th2-type he lper, 350 with UV-specific DNA damage, 714 xeroderma pigmentosum, 68

Cell D ensity and C ulture Factors R egulate Keratinocyte Commitment to Differentiation and Expression of Suprabasal K1IK10 Keratins , Poumay Y, Pittelkow MR, 271

Cells with UV-Specific DNA Damage Are Present in Murine Lymph Nodes Afte r In Vivo UV Irradiation, Sontag Y, Guikers CLH, Vink AA . de Gruijl FR , van Loveren H , Garssen J , Roza L, ICripke ML, van der Leun JC , van Vloten W A, 734

Cervical intraep ithe1ialneoplasia , 138 C57BL/6 mice, 523 C hanges in Expression of Apoptosis-Associated Gencs in Skin Mark Early

C atagen, Seiberg M, Mat·thinuss J , Stenn KS, 78 Changes in the Concentrations of Extracellular Mg ++ and Ca ++ Down­

R egulate E-Cadh erin and Up-Regulate a 2 /3, Integrin Function, Activating Keratinocyte Migration on Type I Collagen, Grzesiak JJ , Pierschbacher MD , 768

C haractcristic Cytokincs Gcnerated by Keratinocytes and Mononuclear !nEutrates in Oral Lichen Plat1us, Yamamoto T, Osaki T , 784

C haracterization of Para neoplastic Pemphigus Autoantigens by Immunoblot Analysis, Hashimoto T , Amagai M, Watanabe K, Chorzelski TP, Bhoga l BS, Black MM, Stevens HP, Boorsma DM, Korman NJ, Gamou S, Shimizu N , Nishikawa T, 829

C haracterization of Two Distinct Calcium-Binding Sites in the Amino­Terminus of Human Profilaggrin, Presland Rl3 , Bassuk J A, Kimball JR, Dale BA , 218

C hemokinesis, melanocyte, 256 C hemotaxis, melanocyte, 256 Cluonic

plaque-stage psoriasis, 725 wounds, 236

C hymotryptic enzyme, stratum corneum , 819 C icatricial pemphigoid, 370 C IN , 138 C Ion cd human papillomavirus type 16 DNA, 277 Co-Administration ofI nsulin-Like Growth Factor (IGF)-I and IG F-Binding

Protein-l Stimulates Wound Healing in Animal Models, Tsuboi R, Shi C-M. Sato C. Cox GN, Ogawa H , 199

Coagula tion depth , Limited , 798 COL7A! genc. 803 Collagen

production stimulation. 128 type I, 768, 750 type Ill , 750 type VlI

gene COL7 A 1, 803 triple- he lica l domain , 438

Collagcnasc alteration in cel.l morphology and, 11 8 interstitial. 1.94, 982

Collagenase Express ion Is Rapidly Induced in Wound-Edge Keratin ocytcs Aftcr Acute Injury in Human Skin. Persists D Uli ng H ealing , and Stops at Rc-Epithe1ialization , Ino uc M, Kratz G, Haegerstrand A, St,\hle-Biickdahl M, 479

Combined Pho tomcdicine Socicty/ American Society fo r P hotobiology Meeting-June 28, 1994, Scottsdale, Ari zona , lII eet;/lg rep0l1, Lim HW. 880

Common Kerati n 5 Gene Mutation in Epidermolysis Bu1.losa Si.l1lplex­Weber-Cockaync, A, /lwtnt;ll/l rep0l1, Ehr lich P. Sybert VP. Spencer A, Stephcns K, 877

Comparativc Epidcmio logy of Pemphigus in T unisia and France: Unusual Incidence of Pemphigus FoLiaceus in Young T U11isian Women , Bastuji-Garin S, Souissi R, Blum L, T urki H , Nouira R, J omaa 13, Zahaf A, Osman AD, Mokhtnr I, Fazaa 13, R evuz J , Roujeau J-C . Kamoun MR, 302

SUBJECT AND T ITLE INDEX 1029

Comparative Genetic Association of Human Leucocyte Antigen C lass II and Tumor N ecrosis Factor-Alpha with Dermatitis Herpetifomlis, Wil­son AG, Clay FE, C rane AM, Cork MJ , Duff GW, 856

Comparative Study of H epatocyte Growth Factor/Scatter Factor and Keratinocyte Growth Factor Effects on Human Kera tinocytes, Sato C, Tsuboi R, Slu C-M, Rubin JS, Ogawa H, 958

Confocal microscopy, 95 scanning laser microscopy, 946

Connective tissue-epithelial junctions in human skin , 90 Contact hypersensitivity

effects of UVD radiation on expression of, 18 loca l suppression of, 287 murine, inlubition by anuloride, 38 UVD-induced local immunosuppression of, 364

Contraction, wound, inlubition, 345 Corneocytes

serum-trea ted , 297 systematic changes in, 530

Corneocytes Undergo Systematic C hanges in Element Concentrations Across the Human Inner Stratum Com ew11 , Warner RR, Bush RD, Ruebusch N A, 530

Corneuln , stratuITI

chymotryptic enzyme, 819 clastic properties of, 806 extracellular space, 819 human inner, 530

Conufied cell envelo pe(s) involucrin immunolabeLing within, 391 precursor(s)

proline rich-related, 204 proteins, 902

C3H/HeJ Mo use Model fo r Alopecia Areata, Sundberg Jp, Boggess D . MontagutelLi X, Hogan ME, KiJ1g LE Jr, 16S

Culture(d) cells, ferrochclatase in . 497 epitheli al cells, lustiotypic, 989 fibrobla sts, nonnal dem1al. 128 human

keratillocytes inhibition of proliferation in, 976 interl eukin-l 0 production by, 3 oxidative stress suppression, 355

melanocytes, 83 skin fibrob lasts, 503

keratinocytes. 384 melanocytes, autologous. 24S skin substitutes, 345

C u.ltured Human Hair Follicles and Growth Factors. Plulporc MP, Sanders D, Kealey T, 44S

Cutanea tarda, porphyria , overt fu milial. 500 C utan eous

foam cell formation in mice, 246 Merkel cells, 910 nerves in alopecia areata, 28S pharmacology, 839 T-ce l.l lymphoma, 537, 889

Cutaneous Permeability Barrier Disruption Increases Fatty Acid Synthetic Enzym e Activity in the Epiclermis of H airless Mice, Ottey KA. Wood LC, Grunfe ld C, Elias PM, Feingold KIl, 401

CycIosporin A, treatment of severe psoriasis with. 189 Cytokeratin 20 Is a General Marker of C utaneous Merkel Cell s While

Certain N euronal Proteins Arc Absent, Moll I, Kuhn C. Moll 1"1.., 910 Cytokinc(s)

in alopecia arcata, 9S - induced ICA M-l expression. 489 pattents in "Iopecia arcata, 14S production. 784

Cytokine-lnduced ICAM-l Expression in HUmatl Keratinocytes Is Highly Variable in Keratinocyte Strains fro m Different Donors, Middleton MH, N oms DA, 489

Cytokine PattenlS in Alopecia Area ta Before and After Topical Immuno­therapy, Happle R, Holfmann 1"1... 14S

Cytokines and Dermal Papilla Function in Alopecia Areata, McDonagh AJ G, Elliott KIl, Messenger AG, 9S

Cytotoxicity, immunologic, in alopecia arcata, 8S

1030 SUBJECT AND T ITLE INDEX

D

DEBR rat sera, 34S Decarboxylase, uro porphyrinogen gene, 500 Decorin , 503 Defcctive TCR Surface Expressio n Associated with Impaired TCR Beta­

C hain Asscmbly in a Patient with C utaneous T-Cell Lymphoma, Pischer MD, Hauber I, P6dingcr M, WolfHM, T ho n V, Donath P, Eibl MM, Knoblcr RM, 537

Defects of Pelage Hairs in 20 M o usc Mutations, H ogan ME, King LE J r, Sundberg JP,3 1S

Delayed Assembly ofDesmosom es in Kerati nocytcs with Disrupted C lassic­Cadherin-Mediated CeU Adhes ion by a Dominan t N egative Mutant, Amagai M, Pujimori T, Masunaga T, Shimiz u H, N ishikawa T, Shimizu N, Takeichi M, Hashimoto T, 27

Dendritic epidermal cell s, 287 T -ceU conjugates, 11

Dermal ce ll s in skin grafts, 21 S endothelial cell s, human , 101 fibrobla sts

adhesion and sprcading of, 844 cu ltured normal, 128 decrease of types I and III proco ll agcn mRNA leve ls in , 282 expression ofTNP gene by, 318 healthy human and scleroderma, 124

papilla cells in alopccia arcata, 8S -epithelia l junction in normal scalp anagcn fo ll icles, 90 function in alopecia areata, 9S in alopecia arcata, 7S

wound hea ling, 850 Dermatitis herpetiformis. 744, 856 Dermatoses, non-psoriati c. 251 De rmis, normal , 241 Desmocollins, 54 1 Desmoglein , 146 Desmoglcin- l , 323 Desmosomal plaquc protein , intracytoplasmic, 720 Desmosomes, 27 Desmoyokin/ AHNAK Protein LocaEzes to the Non-Desmosomal Kerati­

nocyte CeU Surface of Human Epidermis, Masunaga T, Shimizu H , Ishiko A, Pujiwara T. Hashimoto T . Nishikawa T, 941

Dexamethasone, 503 D iabetic mice. 199. 850 Diacylg lycero l. biphasic, production, induced. 835 Diagnosis of m astocytos is, 937 Differences Bctwecn Connective T issue-Epithelia l Junctions in H uman

Skin and the Anagen Hair Po ll icle, Nutbrown M , Randall VA , 90 D ifferences in lnvolucrin Immunolabeling Withi n Cornified Cell Envelopcs

in Nonnal and Psoriatic Epidermis. Ishida-Yamamoto A, lizuka H . 391

Differcnt Effects of Basic Pibroblast Growth Pactor and T ransforming Growth Pactor-f3 on the Two Plate let-Derivcd Growth Pactor Receptors' Exprcssion in Scleroderma and H ealth y Human Dermal Pibroblasts, Ichiki Y. Smith E. LeRoy EC, Trojanowska M. 124

Differentia l R egulation of Decori n ;1I1d Biglycan Gene Expression by Dexamethasone and Retinoic Acid in C ultured Human Skin Pibro­blasts. Kiihari V-M, Hiikkinen L. WestermarckJ, La rjava H , 503

Differentia l R.egulation of Plasminogen Activation ill N ormal Kcratinocytcs and SCC-4 Cel ls by Pibroblasts, BOXJnan ILA, Q uax PHA . L6wik CWGM. Papapoulos SE. Verheij en J , Ponec M . 374

D iffercntial Responsivcness of Langerhans CeU Subsets of Varying Pheno­typic States in Norma l Human Epidc rmis. Shibaki A. Mcu nicr L, Ra C. Shimada S, Ohkawara A, Coopcr KD. 42

D ifferentiation-Induced Enh ancement of the Abi lity of C ultured Human Keratinocytes to Suppress Oxidative Stress , Vessey DA. Lee K-H, Boyer TD, 355

Diphenylcyclopropenone, topica l. 36S Direct Imaging of Molecular Transport Through Skin . Scott ER, Ph ipps JB.

White HS. 142 DJM cell s. inositol 1.4.5-trisphosphate in . 33 DNA

-based prenata l diagnosi s of recessive dystrophic epidermolysis bullosa. 456

BOlTe/in blllgd(IIJeri-specific, 23

THE JOURNAL OF INVESTIGATIVE DERMATOLOGY

damage cell s with UV-specific. 734 ultrav iolet and singlet oxygen-induced. 68

papill omavirus, type 16, human cloned. 277 repair, 287. 933

DNA-Based Prenata l Diagnosis of Generalized R ecessive Dystrophic Epi­dermolysis Bullosa in Six Pregnancies at Risk for Recurrence, H ovnanian A. Hilal L. Blanchet-Bardon C . Bodemer C, de Prost Y, Stark CA, C hristiano AM , Dommergues M, Terwilliger J D, Izqu i­e rdo L, Con tcville p. D umez Y. Uitto J . Goossens M . 456

DNA Repair Capacity for U ltrav io let Light-Ind uced Damage Is R educed in Periphera l Lymphocytes from Patients with Basal Cell Carcinoma . Wei Q, Matanoski GM . Parmer ER, H edayati MA . Grossman L, 933

Dom inant dystrophic epidermolysis bullosa, 438 Dsg

1 antigen . 54 1 3

antigen. 54 1 human , 720

Dye laser. pul sed. flas hlamp-pumped. 798 Dysplastic ncvi. 340 Dystroph.ic cpidermolysis b ullos"

dominant. 438 recessivc, 456

E-cadherin , 293, 768

E

Ed ematogenic potential of phototherapy sources in hai rl ess mousc skin , 359 Effect of Topica ll y Applied Tocopherol o n U ltraviolet Radiation-Mediated

Prce Rad ica l Damage in Skin , Jurkiewicz BA. Bissett DL. Buettner G R., 484

E4 protein, 138 EGP, 113 EGP/TGP-alpha- independent pathway, kerati nocyte migration thro ugh,

729 Eicosatrieno ic ac id. 47 Elafin. SKALP/, 189 Elastin synthes is in fibrob lasts, 241 Electron

microscopy, 86, 134,417 paramagnetic resonance, 484 paramagnetic resona nce spectroscopy. 514

Embryonic, human , skin . 41 '1 Endogenous prostaglandin E2 syn thesis. 52 Endothe lia l

cdls dermal, human. 101 111i crovascular, illilnan , 266

growth f.1ctor, v'lscular alopecia hair follicles. human. in . 18S hUI113n keratinocyte expression in , 7

Endothel ioma cell s. 824 Engraftme nt promotio n , 345 En hancemen t of Delayed Hypersensitiv ity Inflammatory Reactio ns in

G uinea Pig Skin by 12(R)-Hydroxy-5.8. 14-Eicosatrieno ic Acid. Conners M S. Sch wa rtzman ML, Q uan X, H eilman E. C hau han K. PalckJR, Godfi'ey HP, 47

Envelopes. cornified cell . 39'J Enzym e

activity, f.1tty acid synthetic, 401 c hymotryptic, stra tum corne um , 819

Ep idemio logy of pemphigus, comparative, in Francc and T Ulli si". 302 Epidermal

basemcnt membrane, 370, 1008 ce ll s

dendritic, 287 in skin grafts, 21 S

c ulture m odel. serum-free, 107 damage. 798 g rowth f.1ctor, 107, 113 keratinocytes, hum an, integrin expression by, 260 Langcrhans ce ll s 995. proteins, 405

Ep idermal Damage and Limited Coagulation Depth with the Plash Iamp­Pumped Pulsed Dye Laser : A Histochemica l Study, Hohcnlcutner U . l-li.lbert M , Wlotzkc U. Landthalcr M , 798

VOL. 104, NO.6 JUN E 1995

Epidermal Fatty Acid Oxygenases Are Activated in N on-Psoriatic Derma­toses, Bae r AN . Klaus MV , Green FA , 251

Epidcrmis human

expression of transglu taminase 1 in, 211 nerve fibers w ithin ,134, non-desmosomal kcratinocyte ccll surface, 941

normal, 42, 391 psoriatic, 391 sun- cxposed,928

Epidermolysis bullosa acquisita , 23 1 atrophic benign, 467 dominant dystro phic, 438 dystrophic , reccss ive, 456 Herlitz's junctional, 462, 434 pretibial, with lichcnoid features, 803 simplcx-W cbcr-Cockayne, 877

Epidennolytic palmoplantar keratoderma, 425, 430 Epithelial

cell (s) culture, histiotypic, 989 differential scnsitivity of pro li ferating, 183

- conncctive tissue junctions in human skin, 50 skin tumors, non folli cular, 396

Epitheli al Differcntiation Fails to Support R eplication of C loncd Human Vapillomavirus Type 16 DNA in Transfcctcd Kcratinocytes , Brune W , Durst M. 277

Epithclium, 763 Erythema multiforme, 744 Erythropoietic protoporphyria, mctabolic dcfect in , 497 E6 and E7 protcin, 138 Eumelanin:phaeomelanin ratio in cultured hUlllan melanocytes, 83 Evidence T hat Stratum Corneum C hymotryptic Enzymc Is Transported to

the Stratum Corneum Extracellular Space Via Lamcllar Bodies, Sondell B, Thornell L-E, Egc lrud T, 819

Exclusion of Inte rlcukin-l R eccpto r Antagonist as a Primary Disease Determinan t for Psoriasis , letter, R osbotham JL, Barker JNWN , Trcmbath R C, 306

Exon 14, 462 Exon-skipping, homozygous , mutation in thc LAMC2 gene, 434 Expression of C athepsin D in Primary and Metastatic Human Melanoma

and Dysplastic N evi, Podhajcer OL, Bover L, Bravo AI, Ledda Mf, Kairiyama C, Calb I, Gucrra L, Capony F, Mordoh J , 340

Expression of T ransglu taminase 1 in I-Iuman Epidcrmis, Kim S-Y, C hung S-I, Yoneda K, Steincrt PM , 211

Expression of the Tumor Necrosis Factor Gene by Dermal Fibroblasts in R.esponsc to Ul travio let Irradiation or Lipopolysaccharide, de Kos­sodo S, Cruz PD Jr, Dougherty I, T hompson P, Silva-Valdez M , Beutlcr B, 318

Extrace llular matrix, 118,24 1. 282 Mg++ and Ca ++ . 768 space, stratum corneum, 819

F

Failure to Detect In tcrlcukin (IL)-3 mI~A or Protein in Human Kcraci­nocyte,: Antibodies to Granulocyte Macrophagc-Colony-Stimulat­ing Factor or lL-6 (But Not IL-3) N eutrali ze " IL-3' , Bioactivity, Ko ndo S, C iarle tta A, T urncr KJ, Sauder DN, McKcnzie RC, 335

Factors Mediating the Interactions Between Epidermal and Dermal Cells jn Skin Grafts that Might Be Important fo r H air Foll.icle Dcvelopment, Kartasova T, Scandurro AD, Denning MF, Wi.rth PJ , Yuspa SH, Lichti U, 2 :1 S

FamiliaJ po rphyria cuta nca tarda, overt, 500 Fatty acid

o"J'genases, cp ide rmal, 251 polyunsaturated, enriclmlent, 964 synthctic enzymc activity in mouse cpidcrmis, 401

Ferrochelatase in cultured ce ll s, 497 Fctal skin, 411 Fiber(s)

hai r fo llicle reco nstruction and, 39S nervc, 134

Fibroblast(s) dermal, 124, 128, 282, 318, 844 clastin synthesis in , 241

SUBJECT AND TITLE INDEX 1031

enhan cement of melanocyte survival and mel 3I~in, 859 growth factor

acidic, 850 effects on the two platelet-derivcd receptors, 124 in the hairless mouse. 17S -induced down-regulation of the a6/34 integrin complex, 266 receptors 916

hmnan cultured skin. 503 keloidal, 128

regulation of plasminogen activation and SCC- 4 cells in norm al keratinocytes, 374

scar, no rmal and hypertrophic, 118 3T3, 999 transduced, 171

Fibroblast Growth Factor and the Hair Cycle of the Hairless Mouse. du Cros DL, 17S

Fibronectin tropoelastin. 518 type III homology region of the N C1 domain, 231

Sa, type I, reductase, 775 5% minoxidil , 36S FK506, 523 Flashlamp-pumped pulsed dye laser, 798 Foam cell , cutaneous, fo rmation in mice. 246 Foliaceus pemphigus

autoantibodies pathogenic in , 89 5 reaction with the extracellular domain of desmoglein-1. 323

Brazilian , 541 in young T unisian women, 302

Follicle(s) hair

alopecia areata, 13S , 18S -derived tumors, 396 anagen, 90, 42S autoantibodies, 34S black and yellow, 792 cultured . human, 44S development, 411, 21S, 43S fiber reconstruction and, 39S melanocyte, human , 86 proteins of tile mammalian. 40S scalp , in alopecia arcata, 12S stem cells, 38S

France, comparative epidemiology of pemphigus in T unisia and, 302 Free radical(s)

damage in skin. 484 skin of hairless mice, in, 514

Frcquent 1'53 Accumulation in the C hronically Sun-E.'''P0sed Epidennis and C lonal Expansion ofp53 Mutant Cell s in the Epidermis Adjacent to Basal Cell Carcinoma , Urano Y, Asano T, Yoshimoto K, Iwahana H , Kubo Y, Kato S, Sasaki S, Takeuchi N. Uchida N. Nakanishi H. Arase S. Itakum M , 928

G

Ganglioside GQll,-induccd biphasic diacylglycerol production, 835 Gelatinase(s)

activatcd, 236 keratinocyte groWtll factor stimulation of, 989

Gene(s) apoptosis-associated, in skin, expression of, 78 collagen , type VII, COL7A1, 803 encoding the /33 chain in atrophic benign epidermolysis bullosa, 467 expression in isolated hair follicles, 20S histocompatibili ty, transgenic class II major, in murine Langerhans cells,

329 I-ILA, classical, 37S homeobox. Msx-1 and Msx-2, 711 keratin 5, mutation, 877 keratin 9 muta tions, 425 LAMB3,467 ncurilcll1l11omatosis. 74

1032 SUBJECT AND T ITLE INDEX

novel , within HLA, 37S /'as mutations, 868 somatic therapy, 171 TNF expression, 318 TNF-a expression, 526 transfer, 313 uroporphyrinogen decarboxylase, 500

Genetic Linkage Between the Collagen Type VII Gcne COL7A1 and Pretibial Epidennolysis Bullosa with Lichenoid Features, Naeyaert JM, Nuytinck L, De Bie S, Beele H , Kint A, De Paepe A, 803

Gland(s) sweat. development, 411 thym us, 25S

Glucocorticoid Regulation of Elastin Synthesis in Human Fibroblasts: Down-Regulation in Fibroblasts from Normal Dermis But Not from Ke loids, Russell SB. T rupin JS. Kennedy RZ. Russell JD , Davidson JM,241

Glucocorti coid Regulation of Hair Growth in Alopecia Arcata, Sawaya ME, Hordinsky MK, 30S

Glutathione Plays a Key Role in the Depigmenting and Melanocytotoxic Action of N-Acetyl-4-S-Cysteaminylphenol in Black and Yellow Hair Follicles, Alena F, Dixon W, Thomas p. Jimbow K, 792

Glycine-to-Arginine Substitution in the Trip le-Helical Domain of Type VII Collagen in a Family with Dominant Dystrophic Epidermolysis Bullosa, A. C hri stiano AM, Morricone A, Paradisi M, Angelo C, Mazzanti C, Cavalieri R , Uitto J, 438

Glycosaminoglycan production, 128 Grafts

defined cell populations of onto nude mice, 43S skin, 21S -versus-host disease. lupus-like, 177

Granules, lipid lamellar, 405 Granulocyte(s)

involvement in tissue inflammation , 350 macrophagc-colony-stimulating factor, antibodies to, 335

GROa, 789 Growth factor

basic, fibroblast, 266 effects of ep idermal, on morphogenesis, 107 epidermal, 113 fibrob last receptors 916. hepatocyte, 958 keratinocyte, 958 receptors' expression, platelet-derived, in scleroderma, 124 vascular endothelial

alopecia hair fo llicles, human in, 18S keratinocyte, human, expression in , 7

G281 E mutation, 500

HaCaT keratinocytes, human , 58 Hair(s)

cycle of the hairless mouse, 17S fo llicle

alopecia areata scalp , 12S anagen, 90. 42S black and yellow, 792 -derived tumors, 396 development, 411, 2 1S, 43S hun13n

alopecia arcata, 18S cul tured, 44S

H

melanocytes. human , 86 proteins of the mammalian, 40S stem cel ls, 38S

growth, glucocorti coid regulation in alopecia arcata, 30S pelage, 31 S

Hair Follicle and Fiber Reconstruction. Reynolds AJ. Lawrence C M, Jahod:, CAB, 39S

Hair Follicle Autoantibodies in DEBR Rat Sera, McElwee KJ , Pickett p. Ol iver RF, 34S

Hair Folli cle Companion Layer: Reacquainting an Old Friend, RotiUlagel JA, Roop DR, 42S

Hair Follicle Development and Hair Growth from Defined Cell Populations Grafted onto Nude Mice. Lichti U. Scandu rro AB. Kartasova T, Rubin JS. LaR.ochell e W, Yuspa SH, 43S

THE JOURNAL OF INVESTIGATIVE DERMATOLOGY

Haic Follicle Stem Cell s: Present Concepts, Lavker RM. Sun T-T, 38S Hairless mice

fa tty acid synthetic enzyme activity in, 401 skin

free radicals in, 514 hair cycle of, 17S photoaged, 518

Hallopeau-Siemens, 456 Healing, wound, 199 Heat Shock Proteins and Molecular C haperones: Implications for Adaptive

R.esponses in the Skin, May tin EV, 448 Hemoglobin, oxygenated, 421 Hepatocyte growth factor/scatter factor, 958 Hepatoerythropoietic porphyria, 500 H erlitz' s junctional epidemlOlysis bullosa, 434, 462 Herpetifonnis, dermatitis, 856 Histiotypic epitllelial cell cul ture, 989 Hiscocompatibility genes, transgenic class II major. in murine Langerhans

cell s, 329 Hiscopathology of Alopecia Arcata in Horizontal Sections of Scalp Biopsies.

Whiting DA, 26S HLA

alleles, class fI , 4S genes, classical, 37S

HLA-D locus alleles, 5S J-tLA Class II Alleles in Long-Standing Alopecia Totalis/ Alopecia Univer­

salis and Long-Standing Patchy Alopecia Areata Differentiate These Two C linical Groups, Colombe BW, Price VH. IGlOury EL Lou CD, 4S

HLA-Linked Skin Disease: Classical HLA Genes or Novel Genes Within HLA? C haplin DD, Zhou Y, 37S

Horneobox Genes Msx-1 and Msx-2 Are Associated with Induction and Growth of Skin Appendages, Noveen A, Jiang T-X, Ting-Dcrreth SA, Chuong C-M, 711

Hornology region, fibronectin type Ill, of the noncollagenous (NCI) domain, 231

l-tol110Zygous e:xon-skipping mutation in the LAM C2 gem!, 434 one- basepair deletion in exon .. 4 of the LAMB3 gene, 462

I-tPV _associated diseases, 138 t}1ymidine kinase gene transfer ;11 11;110, 313

Hurllan alopecia hair follicles, 18S dermal

endothelial cell s, 101 fibroblasts, hea lthy and scleroderma, 124

Dsg3,720 embryonic skin, 411 epidermal keratinocytes, integrin express ion by, 260 epidermis

expression of transglutaminase .. , 211 nerve fibers in vital layers of, 1.34 non-desl11osomal keratinocyte cell surfi,cc, 941 normal , 42

[-JaCaT kerati nocytcs, 58 hair

follicles cu ltured, 44S mclanocytes, 86

iJ1ner stratum corneum, 530 kcratinocytes

catecholamincs in differentiation of, 953 ' cultured

EGF-mcdiated proliferation, 976 inhibition ofinterferon-y-induced in tercellular adhesion 111 0lcculc- l

expression on, 813 interleukin-10 production by, 3 suppression of oxidative stress in 355 cytokine-induced rCAM-l expression in, 489 failure to detect IL-3 mRNA or protein in, 335 ganglioside GQII,-induced biphasic diacylglycerol production in,

835 growth factor , 958 NCTC 2544, 964 regulation of B7/BD-l antigen by, 763

leukocyte antigen class II , 8S6

VOL. 104 . NO.6 JUNE 1995

macrophages , 52 melanocytes

adult, 755 cultured, 83

nlclanOlna cell line , 916 skin cancer, 309

me~astatic and primary mclanoma. 340 microvascular endothelial cells. 266 l1 oll-lne lan o lna skin cancer, 309 papilloma virus type 16

antiborues to thc E4, E6 and E7 prote ins of. 138 DNA. cloned. 277

polymorphonuclear Icukocyte adhesion, 297 profilaggrin , 218 skin

acute injury in. 479 cells, matrix-associated serine protease inhibitors from . 379 cOllnectivc tissue-epithelial junctions in, 90 fibrob lasts, cultured. 503 inhibition of type I Sa-reductase in. 775 xenografts. 739

transferrin production. 171 Human Dermal Endothelial Cells Express Mcmbrane-Associated Mast Cell

Growth Factor. Weiss Ill'.. Whitaker-Menezes D. Longley]. Bendcr j, Murphy GF. 101

Human Keratinocytcs Express the Thrcc Major Splicc Fonns of Vascular Endothelial Growth Factor, Ballaun C, Weninger W, Uthman A. Weich H. Tschachler E. 7

Human Keratinocytcs Regulate T heir Expression of B7 IBB-l Antigen by a Unique, Calcium-Depcndent Mechanism, Nasir A, Fcrbel B, Gaspari AA. 763

Human Langcrhans Cclls Express E-Cadherin, Blauvelt A, Katz SI, Udey MC,293

Hyperscnsitivity contact

loca l suppression of, 287 murine, inhibition by amiloridc, 38 UVB

-induced local immunosuppression of, 364 radiation cffects on expression of. 18

delaycd, inflammatory rcactions, 47 Hyperthermia, 62 Hypertrophic scar(s)

burn, 750 fibroblasts , 11 8

I

ICAM-l cxpression. cytokine-induced, 489 transcriptional regu lation of. 970

Idcntification of a Homozygous Exon-Skipping Mutation in the LAMC:Z Gene in a Patient with Hcrlitz's junctional Epidcrmolysis Bullosa, IIIlIlnlil", ,.cp0/1. Vailly j , Pulkkincn L, Christiano AM. Tryggvason J{,

Uitto j, Ortonne j-P, Meneguzzi G. 434 Identifi cation of a Homozygous One-Basepai~ Deletion in Exon 14 of. the

LAMB3 Genc in a Patient with Herlitz junctional Epidennolysis Bullos', and Prenatal Diagnosis in a Family at Ilisk for R.ecurrencc , Vaj\Jy j, Pulkkinen L, Miquel C , Christiano AM. Gerecke D, Burgeson R.E, Uitto j, OrtOlUle j-p. Mencguzzi G, 462

IGF-binding protcin. 199 IGF-l, 199 IgG pcmphigus, 33 IL-3, 335 IL-6, 335 IL-8,789 Imaging of molccular transport through skin. 142 Immunity to Hair Follicles in Alopccia Arcata, Tobin OJ, Bystryn j-C. 135 Immunoadsorption. antigcn-specific, of pathogcnic autoantibodies in pem-

phigus foliaccus. 895 Immunoblot analysis. characterization of paraneoplastic pemphigus autoan­

tigcns by, 829 Immunodominant Autocpitopes of Type VII Collagen Are Short, Pail:cd

Peptide Sequcnces Within the' Fibroncctin Type III Homolc.gY

SUBJECT AND TITLE INDEX 1033

Region of the Noncollagenous (NC1) Domain,jones DA, Hunt SW 1II. Prisayanh PS. Briggaman RA, Gammon WR, 231

Immunoelectron microscopy, 101 Immunoglobulin E-Binding Structures on Antigen-Presenting Cells Present

in Skin and Blood. re"icIII. Maurer D, Stingl G, 707 Immunohistochemical expression of small proteoglycans, 509 Immunolocalization of keratinocyte muscarinic acetylcholine receptors. 95 Immunologic Cytotoxicity in Alopecia Are~ta: Apoptosis of Demlal Papilla

Cell s in Alopecia Areata. Norris DA. Duk\! R. Whang K, Middleton M.8S

Immunosuppressant FK506, 523 Immunotherapy, topical, in alopecia areata

adults, 14S children, 35S

Impaired TCR beta-chain assembly, 537 Improved Diagnosis of Mastocytosis by Measu~ement of the Major Urinary

Metabolite of Prostaglandin D2 , Morrow]D. Guzzo C. Lazarus G, Oates jA. Roberts Lj II ,243

In T llis Issue, 1. 169. 307, 441. 705, 881 Increased E.xprcssion of Vascular Penneability Factor (Vascular Endothelial

Growth Factor) in Bullous Pemplligoid, Dennatitis Herpetifonnis, and Erythema Multifomle, Brown LF, Harrist Tj. Yeo K-T, St~ltle­Biickdahl M, jackman 1'. W, Berse B, Tognazzi K, Dvorak HF, Detrnar M, 744

Increased Types I and III Collagen and Transfomling Growth Factor-J31 mRNA and Protein in Iiypertrophic Burn Scar, Zhang K. Gamer W, Cohen L, Rodriguezj, Ph an S, 750

Induction of Anagen in Telogen Mouse Skin by Topical Application of FK506, a Potent Immunosuppressant, 523

Inflammation irritant-induced, 421 tissue, 350

Inflammatory reactions, delayed hypersensitivity, by 12(R)-hyroxy-5,8.14-eicosatrienoic acid, 47

Inllibition of Interferon-y--Induced Intercellular Adhesion Molecule-1 Ex­pression on Human Keratinocytes by Phosphorothioate Antisense Oligodem..'ynucleotides Is the Consequence of Antisense-Specific and Antisense-Non- Specific Effects, Hcrtl M, Neckers LM. Katz SI, 813

Inhibition of Melanoma Growth by Adenoviral-Mediated HSV Thynlidine Kinase Gene Transfer 1" Vivo, Bonnekoh B, Greenhalgh DA, Bundman DS. EckJlardt jN, Longley MA, Chen S-H, Woo SLC, Roop DR., 313

htllibitor, tissue . of metalloproteinases , 52 Inner stratum corneum, human, 530 Inositol 1,4.5-trisphosphate in DjM cells, 33 Insulin

in cultured human keratinocytes , 113 -like growth f.,ctor-l, 199

Integrin E.xpression by Human Epidennal Keratinocytcs Can Be Modulated by In terferon-y, Transfornlin g Growth Factor-J3. Twnor N ecrosis Factor-a, and Culture on a Dennal Equivalent, Hertle MD. Jones PH, Groves RW, Hudson DL, Watt FM, 260

Intercellular adhcsion molecule -1 ,350.813 -3 on human epidennal Langcrhans cells, 995

Intcrcellular Adhesion Molccule-3 (CD 50) on Human Epidennal Langer­hans Cells Participates in T-Cell Activation, Teunissen MBM, Koomcn CW, Bos]D 995,

Intcrferon(s) dccrease of types I and III procollagen mRNA levels by. 282 -y

-induced intercellular adhesion molecule-I, 813 keratin 17 expression in HaCaT keratinocytes by. 58 MMp-l and MMp-3, upregulation by. '384 modulation of integrin expression by human epjdennal keratinocytes

by. 260 Interferon-f Coordinately Upregulates Matrix Metalloprotease (MMP)-l

and MMP-3 , But Not Tissue Inllibitor of Metalloproteases (TIMP), Expression in Cultu red Keratinocytes. Tamai K, Ishikawa H. Mau­viel A, Uitto j, 384

Interleukin -alpha. 729 - I rcccptor antagonist. 306. ISS -3 mRNA, 335 -8, 789 -10,3

1034 SUBJECT AND TITLE INDEX

Interleukin-1-Alpha Stimulates Keratinocyte Migration Through an Epider­mal Growth Factor/Transfonning Growth Factor-Alpha-Indepen­dent Pathway, Chen JD, Lapiere J-C, Sauder DN, Peavey C, Woodley DT, 729

Interleukin-8 and GROa Prime Human N eutropluls for Superoxide Anion Production and Induce Up-Regulation ofN-Fonnyl Peptide Recep­tors, Metzner B , Barbisch M, Parlow F, Kownatzki E, Schraufstatter I, Norgauer J , 789

Interleukin-10 Production by Cultured Human Keratinocytes: Regulation by Ultraviolet B and Ultraviolet A1 Radiation, Grewe M, Gyu£ko K, Krutmann J, 3

Interstitial collagenase, 194 , 982 Interstitial Collagenase Is Expressed by Keratinocytes That Are Actively

In volved in R eepitheliaHzation in Blistering Skin Diseases, Saari­alho-Kere UK, Vaalamo M, Airola K. Niemi K-M, Oikarinen AI. Parks WC. 982

Intracellular calcium, 33 In tracytoplasmic desmosomal plaque protein, 720 Introduction to Supplement, Price VH, Moshell AN, Stenn KS, Goldsmith

LA, Norris DA, I S I/I Villo Confocal Scanning Laser Microscopy of Human Skin: Melanin

Provides Strong Contrast, Rajadhyaksha M, Grossman M, Esterow­itz D, Webb RH, Anderson RR. 946

[/I Villo Detection of Anthralin-Derived Free Radicals in the Skin of Hairless Mice by Low-Frequency Electron Paramagnetic Resonance Spec­troscopy, Mader K , Bacic G, Swartz HM, 514

Involucrin immunolabcling, 391 Involvement of Granulocytes and the Adhesion Receptors Intercellular

Adhesion Molecule-1 and Lymphocyte Function-Associated Anti­gen-1 in Tissue Inflammation Induced by T h2-Type Helper Cells, Muller KM, Jaunin F, Masouye I. Piguet P-F, SauratJ-H. Hauser C , 350

Invqlvement of Phospholipase D in Ganglioside GQII,-Induced ~iphasic Diacylglycero l Production in Human Kcratinocytes, Seishima M, Aoyama Y, Mori S, N ozawa Y , 835

Irradiation, ultraviolet. 475 . 734 Irritant-induced inflammation, 421 Is the Dermal Papilla a Primary Target in Alopecia Areata?, Randall VA,

MacDonald Hull SP, Nutbrown M, Calver NS, Parkin SM, C unliJfe WJ,7S

Is Trachyonychia , a Variety of Alopecia Areata, Limited to the Nails? , Tosti A, Bardazzi F, Piraccini BM, Fanti PA, Cameli N, Pileri S, 27S

Isolation and Long-Term Culture of Human Hair-Follicle Melanocytes, Tobin DJ, Colen SR, Bystryn J-C, 86

Isolation of a Unique Melanogenic Inhibitor from Human Skin Xenografts : Initial [/I Vill'O and III Vivo Characterization, Farooqui JZ, Robb E, Boyce ST, Warden GD, Nordlund JJ, 739

Isopeptidc bond formation, 204

J Junctional epidemlOlysis bullosa, H erlitz' s, 434

Keloidal fibrob lasts, 128 Keloids, 241 Keratin(s)

5 gene mutation, 877 9 gene mutations , 425, 430 16,396 17, 58, 396 suprabasal K1 IK1 0, 271

Keratinocyte(s) apoptosis of, 922 cultured

hUlnan

K

catecholamines in differentiation of, 953 cytokine-induced ICAM-1 expression in. 489 inhibition of interferon ')I-induced intercellular adhesion molecule-l

expression on. 813 EGF-mcdiated proHferation of, 976 insulin in , 113 express ion by of 3 major splice form s of vascular endothelial growth

factor, 7 f.1i lure to detect IL-3 mRNA or protein in, 335

THE JOURNAL OF INVESTIGATIVE DERMATOLOGY

ganglioside GQII,-induced biphasic diacylglycerol production in, 835 interferony expression in, 384 interleukin-10 production by, 3 Keratinocyte(s) human , growth factor, 958 Keratinocyte(s) human. N CTC 2544, 964 regulation of B7 IBB-1 antigen by, 763 suppression of oxidative stress, 355

delayed assembly of desmosomes in, 27 enh'U1cement of melanocyte survival and melanin, 859 epidermal, human, integrin expression by, 260 expression of interstitial collagenase by, 982 growth factor stimulation, 989 Dsg3 in, 720 BaCaT,58 interactions of with epidermal basement membrane, l008 - ke ratinocyte interactions, 146 migration, 729, 768 muscarinic acetylcholine receptors, 95 non-desmosomal, cell surface of human cpidemlis, 941 normal, plasminogen activation in, 374 oral , 784 T - cell adherence to, inhibition of by pentoxifyUine 1004 transfected, 277 wound-edge, 479

Keratinocyte Growth Factor Stimulation of Gelatinase (Matrix Meta llopro­teinase-9) and Plasminogen Activator ill Histiotypic Epithelial Cell Culture, Putnins EE, Firth JD , Uitto V-J, 989

KeratUlOcyte Muscarinic Acetylcholine Receptors: Immunolocalization and Partial C haracterization, Grando SA, Zelickson BD, Kist DA. W ein­shenker D, Bigliardi PL, W endel schafer-Crabb G, Kelmcdy WR, Dahl MV, 95

KeratUlOcytcs and Fibroblasts in a Human Skin Equivalent Model Enhance Melanocyte Survival and M elanin Synthesis After Ultravio lct Irra­diation, Archambault M, Yaar M, Gilchrest BA, 859

Keratoderma, epidermolytic palmoplantar, 425, 430 Kinase , HSV thymidille, gcne transfer. 313 Kinetics, cell- cycle, 755 Kirk D Wuepper, M.D ., 'filmle. Hanifin JM , 446

LAM.B3 gcne, 462, 467 Lamepar

bodies. 819 lipid, granules, 405

Laminin 5, altered expression , 467 Lange rhans cell(s)

epidermal, 995 e"press E-cadherin, 293

L

murinc, transgcnic class II major histocompatibility gcnes in , 329 subsets of varying phenotypic states in normal human epidcrmis. 42

Laser dye, pulscd, flashlamp-pumped, 798 microscopy, confocal scanning, 946

Lesions of localized scleroderma. 23 Le ukocyte(s)

adhesion, human, polymorphonuclcar. 297 antigen class II, human, 856

Levels of Skin-Derived Antilcukoprotcinase (SKALP)/Elafin ill Serum Correlate with Discase Activity During Treatment of Scvcre Psori­asis with Cyclosporin A. Alkcmadc HAC , deJongh GJ, Arnold WP. van de Kerkhof PC M. Schalkwijk J , 189

Lichen planus, oral, 784 Lich enoid fcatures. pretibial , epidermolysis bullosa with, 803 Lipid

lamellar granules, 405 p !,roxidation, 964

Lipopolysaccharide, 318 Locus alleles , HLA-D, 5S ' Lorierin Expression Is Coordinatcd with Other Epidemlal Proteins and thc

Appearance of Lipid Lamellar Granules ill Development. Bickcn­bach JR, Greer JM , Bundman DS, Rothnagcl J A, Roop DR. 405

Loss of Vascular Endothelial Growth Factor in Human Alopecia Ha.ir Follicles, Gillespie GY, Goldman CK, Tsai J-C, Soroceanl1 L, 18S

Lupus erythcmatosus, bullolls, systemic, 231 _ like graft-versus-host di sease, 177

VOL. 104 . NO.6 J UNE 1995

Lymph nodes. murine. 734 Lymphocyte(s)

e ffector, 177 fun ction-associated antigen-l in tissue inflammation , 350 peripheral, 933 T, memory, 11

Lymphoid ce ll s, 183 Lymphom a

cutaneous T-cell , 537 T-cell , cutaneous, 889

M

Macro phages , hm,., an, 52 M agnetic resonance spectroscopy. 13C-nuclear, 806 Malignant melanoma, nonmetastatic primary. 868 M ammals, alopecia arcata in , 32S Mast celJ (s)

d iagnosis and di sease. 885 fibrogenic for 3T3 fibrob lasts , 999 growth fa ctor, 10 1.

Mast Cell Disease and Its Diagnosis. editorial, T harp MD. 885 Mastocytosis. diagnosis 937, Matrix(ices)

-associated serine protease inhibi tors, 379 extracellular, 118. 24 1 , 282 meta lloprotease. 384 mewlloproteinase-9 . 989

M echanism of Human Polym orphonuclear Leukocyte Adhesion to Seru l1l ­T reated Corneocytes, Terui T . Z hen Y -X. Kato T , Tagami 1-1 . 297

Melanin provision of strong contrast in laser microscopy of human skin , 946 synthesis. 859

M elanocyte(s) adu lt human, 755 anl c lanotic, 86 chemokines is. 256 chem otaxis. 256 cultured

autologous, 24S IllnTlan, 83

hail' fo llicle , human, 86 survival , 859 ul tJ"3structure abnonnaliLies, 12S

Melanocyte Mi togens Induce Both Melanocyte C hemokinesis and C henlO­ta>";s. H orikawa T, N orris DA . Yo hn JJ, Zekman T . T rave rs JB . Morelli J G, 256

Melanocytic nevi, 475 Melanogenic inhibitor, 739 Melanoma(s)

cell li ne, human, 916 growth inhibition , 313 m alignant, nonmetastatic primary, 868 metastati c, htlli,an. 340 skin cancel'. human , 309

M embrane -associated mast cell growth f.,c tor. 101 basement, epidermal. 1008

Memory T lymphocytes, 11 Merkel ce ll s

cutaneous, 9'10 in human embryo nic and fetal skin , 4 '11

M etabotic defect in e rythropoietic protoporphyri a, 497 Meta lloprotease(s), 384 M eta lloprote in ases

- 1 , 118,236 -9, matrix , 989 inhi bitor of, 52

Metastatic human melanoma , 340 Metho trexate T herapy of Psoriasis: Differentia l Sensitivity of Prolife rating

Lymphoid and Epithelia l Cell s to the Cytotoxic and Growth­Inhibi to ry EA'ccts of M eth otrexate , Jeffes EW\3 III . McCullo ugh.J L, Pitte lkow MR, McCormick A, AlmanzorJ, Liu G, Dang M . Voss K. Vossj , Schlotzhauer A, Weinstein GD , '183

Mg"' + , extrace l.lular. 768 Mice

C57BLi6. 523

ath ymic, 171, 345 diabetic. 199 . 850 hairless

SUBJECT AND T ITLE INDEX 1035

fatty acid synthetic enzym e activ ity in. 401 hail' cycle of. 17S skin

free rad ica ls in. 514 photoaged, 518

model. C3 H / H eJ. for alo pecia arcata, 16S mutations. defects of pelage hajrs in . 31 S nude. defined cell populations grafted onto. 43 skin. telogen , 523

Microdialysis in C utaneous Pharmacology: Kineti c Analysis of Transder­m ally Delivered Nico tine, Hegemann L. Forstinger C, Partsch B, Lagle r I. Krotz S. Wolff K. 839

Microsatell ite In stabil ity in Human Non-Melanom a and Melanoma Skin Cancer. Q uinn AG. Healy E. Rehma.n 1, Sikkink S, R ees JL. 309

Microscopy confoca l, 95 electron. 86. 134, 417 immunoelectron. 101 laser, confocal scanning . 946

Microvascular endothelial cell s, human , 266 Migration, keratinocyte. 729, 768 Minoxidil , 5%, 36S Mi togens, m elanocyte, 256 Mitotoxin resistance 916 , MMP-1 and -3. 384 Molecula r

chaperones, 448 transport. imaging of, l 42

Molecular Ana lys is of Elastic Properties of the tratum Corneum by Solid-State DC-Nuclea r Magnetic Resonance Spectroscopy. J okura Y. Ish.ikawa S, Tokuda H. Imokawa G, 806

Molecular Approach to Alopecia Arcata. A. Skinner RB Jr. Light WHo Leonardi C . .Bale GF. R osenberg EW. 3S

Molecular Staging of Cutaneous T-Cell Lymphoma : Evidence fo r Systemic Involvement in Ea rl y Disease, Veelken H. Wood GS, Sklar J. 889

Moleculc(s) adhes ion . 11 . l008 -3. interce llular adhesion, 995

Monoclona l an tibody M35. 95 Mononuclea r cell s, 784 Montagna. W iUiam . Ph.D., tribl/t/', Kligm an AM. 444 M orphogenesis. de leterio us effects of EGF on . l 07 MRNA

IL-3 . 335 TGF- !31, 750

Msx-l atld Msx-2 hom eobox genes, 71 1 M35 monoclona l antibody. 95 Mucosa , o ral , 224. 546 Murine Langerhans cells, 329 Murine

contact hypersensitivity, inhibition by amiloridc. 38 lymph nodes, 734 skin , 62

M uscalinic acetylcho line receptors. keratinocyte. 95 Muta tion

G281E,500 in the gene encoding the 133 chain in atrophic benign epidertnolys is

bu llosa, 467 in th e J A Dom ain of Keratin 9, 430 kera tin 9 gene. 425 ras gene , 868

Mutation (G28 1 E) of the Human Uroporphyrinogel1 Decarboxylase Genc C auses Both H epatocrythropoietic Porphyria and Overt Familia'! Porphyria C urallea Tarda: Bioch emical and Genetic Studies on Spanish Pati ents. A. R.obcrts AG , Elder G H. Dc Salamanca RE, Herrero C, Lecha M. Mascaro JM, 500

Mutations in the 1 A Domain of Keratin 9 in Patients with Epiderlllo lytic Pa lmoplantar Keratoderma , /III/ratiol/ /'I'pOll. Rotlmagel JA, Wojcik S, Liefer KM . Domine)' AM, Huber M, Hohl D. R oop DR. 430

N

N-acetyl-4-S-cys teaminylp llcno l, 792 Narrow- band photothe ra py sources. 359

1036 SUBJECT AND TITLE IN DEX

N CT C 2544 human kcratinocytes, 964 N ecros is, tumor f.1 ctor

a, 260, 526, 824, 856 , 922 gene, 318

N erves cutan eous, in alopec ia arca ta, 28S fibers, 134

N euril emmom atosis gene, 74 Neurofibromatosis 2 and Neurilemmomatosis Gene Arc Identical, Honda

M , Ami E, Sawada S, Ohta A. Numura M , 74 Neuronal pro tein s, absence of, 910 N eutro phils, GR Oa, prime human , 789 N evi

dysplastic , 340 melanocytic, 475

N - formyl peptide reccptors, 789 Nicotine , transdermally delivered , 839 1994 Annual Meeting o f the Socie te de R echerche Dermato logiquc, T he,

Ecole du Service de Sante des Armces de Lyon, Bron-October 27-29, 1994, 153

1995 Annual Meeting of the Society fo r Investigative D em1ato logy, Sheraton Chicago Ho tel , Chicago, Illinois-May 24-28, 1995, nbstmcts, 554

NPKB,970 No Cell-Surface-Reactive Antibodies Aga inst C ultured A uto logous Mela­

nocytes Pound in Alo pecia Arcata Sera, Kho ury EL, Price VH , 24S N odes , lymph , murine, 73 4 N o Evidence fo r BOlTe/in /mrgdorJeli-Specific DNA in Lesions of Localized

Scleroderma, Wienecke R , Schli.ipen E-M, Zochling N, Neubert U , Meurer M , Volkenandt M , 23

N on-desmosomal keratinocyte cell surface of human epidcrmis. 94 1 fo lbcular epithelial skin tumors, 396 melanoma skin cancer, 309 metastatic primary malignant melanoma, 868 psoriatic dennatoses, 251

Nl e" DPhe7 a -Melanocyte- Stimulating H ormone Increases the Eumelanin : Phaeomchmin R atio in C ultu rcd Human Melanocytes, Hunt G, Kyne S, W akamatsu K, Ito S, T hody AJ , 83

N onnal dermis, 241 epidermis, 42, 391 keratinocytes, plasminogen acti va tion in , 374 scar fi broblasts , 11 8

N ovel genes within H LA, 37S secretory protein /31G-H 3, 844

N uclear fac tor I, 282 Nucleotides, adenosine and adenine, 976 Nutrien ts, topica l, 345

o O ligodeoxynucleo tides, phospho rothioate anti sense, 813 O ncogene, 755 O ncostatin M Stimulates Collagen and Glycosaminoglycan Production by

C ultured N onn al Dermal Pibroblasts: Insensitivi ty o f Sclerodermal and Ke lo idal Pibroblasts, Duncan MR, H asan A, Berman B, 128

l ,4,5-trisphosphate in DJM ceLI s, 33 1A domain of keratin 9 in patients wi th ep idennolyti c palmoplantar

keratoderma, 430 l ,25-dihydroxyvitamin OJ, 11 3 O ral

keratinocytes, 784 lichen planus, 784 mucosa, 224, 546

Osmium Tetroxide and Ruthenium Tetroxide Arc Complementary. R e­agen ts for the Preparation of Epidermal Samples fo r T ransmission Electron Microscopy, Swartzendruber D C, Burnett IH, W ertz PW, Madison KC , Squier C A, 417

O uter roo t sheath of no rmal hair fo lliclcs, 12S Overt familial po rph yri a cutanea tarda, 500 Oxidative stress, abili ty of cultured human keratinocytes to supp ress , 355 Oxygen

- induced D N A damage in xe rodem13 pigmentosllm cell s, 68 single t, 194

Oxygenases, fatty acid, epidennal , 251 Oxygenated hemoglo bin , 421

T HE JO URNAL OF INVESTI GATIVE D ERMATOLOGY

p

Palmoplantar keratoderma, epidermolytic, 425, 43 0 PanCOC11l1Iins: A G roup of Small Proline Rich-Related C ornified Envelope

Precursors with Bifunctional C apabilities in Isopeptide Bo nd Forma­tion, Greco MA , Lo rand L, Lane W S, Baden HP, Parameswaran KNP, Kvedar J C, 204-

Papilla. . derma l alop ecia arcata , 7S ce ll s in alopecia arcata, 8S - epi thelial junction in normal scalp anagen follicles, 90 function in al opecia arcata. 9S

Papillo mas, Shope, 526 Papillo mavirus type 16

antibodies to the E4, E6 and E7 protcins of human, 138 DN A, human cloned, 277

Paral1l agnetic resonance e lectron spectroscopy. 484, 514 Paraneopl astic pemphigus autoantigens, 829 Partial C haracte ri zation of Matrix-Associated Serine Protease Inhibito rs

from Human Skin Cell s, Rao C N, Peavey C L, Liu YV, LapiereJ-C, W oodley DT , 379

Pathogenic au toantibodies in pemphigus fo liaceus, 895 Pel age ha.irs, 31 S Pemph igoid

bullo US. 744 c ica.tri cial , 370

Pemphigus anti g cn , 27 foUaceus

a t.ltoan tibodies, 323 B raziljan, 541 p athogenic autoantibodies iJ1 , 895

IgG,33 in young W omen in France and T unisia, 302 paraneo plastic, autoantigens, 829 vul g ari s

an tigen, 720 a utoantibodies, 323 reactiv ity wi th Dsgl , Dsg3 and desmocollins, 54 1

Pemph i gus Foliaccus and Pemphigus Vulgari s Autoantibodies React w ith thc Ex tracellular Domain of D esm ogle in-"I , Emery DJ, Diaz LA, Fairley JA, Lopez A, T aylo r AF, Giudice Gj. 323

Pemphigus IgG, but Not Bullo us Pemphigoid IgG, C auses a T ransient Increase in Intracellular C alcium 'lI1d Inositoll ,4 ,5-T ri sphosphate in DJM- 1 Cells, a Squamous Cell C arcinoma Line, Seishima M , Esaki C, Osada K, Mo ri S, Hashimoto T, Kj tajima Y, 33

Pentoxify llinc, 282, 824, J 004 Pcntoxifyllinc Inhjbits T -Cell Adherence to Keratinocytl's, Bruynzeell, van

dcr Raaij LMH , Stoof TJ , Willemzc R , 1004 Pentoxifylline Inhibits T umor N ecrosis Facto r-a (T NFa )-lnduced T­

Lymphoma Cell Adhesion to Endothelioma Cells, Weiss jM, Van­scheidtW , Pilarski KA, W eyl A, Peschen M , Schopf E, Vestweber 0 , Simon j C, 824

Pentoxifylline, Pentifylline, and Interferons Decrease T ype I and 1II Pro­collagen mRNA Level s in Dermal Fibroblasts: Evidence for M edi­ation by Nuclear Facto r 1 Do wn- R egulation, Duncan MR, Hasan A, Bennan B , 282

Pepti de, N-form yl, recepto rs, 789 Perip h eral lymphocytes, 933 Pero~dation, lipid , 964 P53 , 928, 883 p53 a nd the Origins o f Skin Cancer, editorin l, !'tees JL, 883 PG P 9. 5 imnlll11ohistochemistry, 134 Phaeomclan.in , ratio to eumelanin in cul tured human melanocytes, 83 Phar(ll aCo logy, cutaneous, 839 Phenotypic st" tes in no rmal human epidermis, Langerhans cell subsets o f, 42 Phospholipase 0 , 835 Pho toaged hairless mo use skin. 518 Photophcresis, 177 Phototherapy sources, broad- and narrow- band, 359 Phototurl1o rigenic Potential o f Droad-Band (270-35 0n.m) and Narrow­

Dand (311-313 nm) Pho totherapy Sources C annot Be Predicted by T hci.r Edcmatogen.i c Po tential in Hairlcss Mouse Skin , Gibbs NK, T ra yno r NJ , MacKic RM, Campbell I,J ohnson BE, Fergusonj , 359

Pigr\:?entosa urti cari a, 101 Pigr\:?en tosurI1 , xeroderma , ce lls, '68

VOL. 104, NO . (. JU NE 1995

Plakoglobin Binding by Human Dsg3 (Pemphigus Vulgaris Antigen) in Keratin ocytes Requi res the Cad herin-Like In tracytoplasmic Seg­ment, Roh J-Y, Stanley JR, 720

P lanus, lichen , ora l, 784 P laque

protein , intracytoplasmic desmosomal, 720 psoriatic, 872 - stage chronic psoriasis, 725

Plasminogen activation in nonnal keratin ocytes , 374 activator, 989

Platelet-derived growth f.,ctor receptors' expression in scle roderma, 12<t PMA-Induction media tion by NF KB, 970 Polarized Expression and Basic Fibroblast Growth Factor-Induced DOW"l1-

R egulation of the 016 (34 In tegrin Complex on Human Microvasclllar Endothelial Cell s, Sepp N T, Cornelius LA, Romani N , Li L-J , Caughman SW. Lawley TJ . Swerli ck RA, 266

Polyacrylamide-transcriptase, -reverse, chain reaction, 20S Polymorphonuclea r leukocyte adhesion, human, 297 Polyunsaturated Fatty Acid Enriclunent Increases U ltravio let A-Indu c d

Lip id Peroxidation in NCTC 2544 Human Keratin ocytes, Quiec p, Mazie re C, Santus R , Andre P, R edziniak G, C hevy F, Wolf C , Dtiss F, D ubertret L, Maziere J C, 964

Porphyria cutanea tarda , overt fa milial , 500 hepatoerythropo ietic, 500

Precursor prote ins, cornified cell envelope, 902 Prenata l diagnosis for H erlitz' junctional ep idermolysis bullosa, 462 Pretibial epidermolysis bullosa with lichenoid features, 803 Primary melanoma, human , 340 Procollagen mRNA levels, types I and Ill , 282 Pro li feration of cultured human keratinocytes, 976 Proline rich

prote ins, 902 -related cornified envelo pe precursors, 204

Prostaglandin O 2 ,937 E2 synthesis, endogenous, 52

Protease , serine, inhibito rs, 379 Protein(s)

cornifi ed cell envelo pe precursor, 902 desll1oyokin l AHNAK, 941 E4, E6, E7, 138 epidermal , 405 heat shock, 448 lGF-binding, 199 in human keratinocytes, failure to detect. 335 in hypertrophic burn scar, 750 in tracytoplasmic desm osol11 al plaque, 720 neuronal, absence of, 910 nove l secretory, (31G-H3, 844 of the mammalian hair fo llicle, 40S proline-rich, 902

Proteoglycans in the tumor tissue and stroma of basa l cell ca rcinoma , 509 m 'lIlllllalian hair fo llicle, 40S

Pro teoglycallS and Associated Proteins of the Mammalian Hair Follicle, Couchman JR. du C ros DL, 40S

Protoporphyri a, eryth ropoietic, metabo lic defects in , 497 Psorias is

interl eukiJl-1 receptor an tagonist as a primary disease deternlinant for, 306

methotrexate therapy of, '183 plaque-stage chronic, 725 severe, treatmellt of with cyclosporin A, 189

Psoriatic epide rmis, 391 plaque, 872

Pulsed dye laser, fl ashlamp-pumped, 798

R

Radiation, UVA alld uvn, 3 Radicals, free, in skin of hairless mice, 514 R as Rns Gene Mutations: A Rare Event in NOl11netastati c Primary M.J.ig­

nant Melanoma , Wagner SN , Ockenfcls H-M, Wagner C, H~fler H, Goos M , 868

R at sera. DEBR. 34S R ecepto r (s)

SUBJ ECT AND T ITLE INDEX 1037

antagonist, interleukin-1, allele of, 15S fi broblast growth factor, 916 interleukin-l, antagonist, 306 keratinocyte muscarinic acetylcho line, 95 N -form yl peptide, 789 repertoire V (3 in alopecia areata, 22S retinoic acid , gamma, 779 T-cell, iu chro nic plaque- stage psoriasis, 725

Reduced Growth Factor Requirements and Accelerated Cell-Cycle Kinet­ics in Adult Human Melanocytes Transforn1ed with SV40 Large T Antigen , Zepter K, Hiiffi,er AC, Trefzer U, Elmets CA. 755

R eductase, type I SOl, 775 Re-epitheliaHzation

in blistering skin di seases, 982 none , in human skin , 479

Regulation of Transgenic C lass II Major HisrocompatibiHty Genes in Murine Langerhans Cells, Longley j, Ding T-g, Levin 0, Lewis J, Edelson R , Tigelaar R , Flavell R , 329

R elative Am ounts of Keratin 17 Are Higher T han T hose of Keratin 16 in Hair-Follicle-Detived Tumors in Comparison with N onfollicular Epithelial Skin Tumors, Yoshikawa K-i, Katagata Y, Kondo S, 396

Repair of U ltraviolet B and Single t O" .. ygen-Induced D NA Damage in Xeroderma Pigm entosum Cells, Riinger TM, Epe B, Moller K, 68

R esonance spectroscopy electron , paramagn etic, 484, 514 13C-nuclear magnetic, 806

R etinoic acid in cultured human skin fibroblasts, 503 recepto r gamma, 779 regulation of oral ep ithelial differentiation by, 224, 546

R etinoic Acid R eceptor Ganun a Mediates Topical R etiJloid Efficacy and lnitation in Animal Models. C hen S, OstrowskiJ, WhitiJlg G, Roalsvig T, Hammer L, Currier SJ, Honeyman j , Kwasniewski B. Yu K-L. Sterz),cki R , Kim C U, Starrettj, Mansuri M, R eczek PR, 779

R etino ic Acid Regulates Ora.l Epitllclial Differentiation by Two Mecha­nism s, Kautsky MD, Fleckman P, Dale BA, 224

Retinoic Acid Regulates Oral Epithelial Dilferentiation by Two Mecha­nisms, coll'ectioll , Ka utsky MD, Fleckman P, Dale BA, 546

R ole of the T hymus Gland in Alopecia Areata, Fenton DA, Tobin OJ, Kenda ll MD, 25S

Root sheath , o u ter, of no rmal hair follicles, 12S Ruthenium tetroxide, 417

s Scalp(s)

alo pecia arcata, biopsies, histopatho logy of in, 26S cwucally nonnal hair fo llicles from, 12S

Scanning, confoca l, laser microscopy. 946 Scar(s)

fibroblasts, hypertropluc and nonnal. 118 hypertrophic bum, 750

Scatter facto r , h epatocyte. 958 SC -4 cells, 374 Sclerodenna

lesions of locali zed, 23 platelet-derived growth f.~ctor receptors' expression in , 124

Secretory protein , novel, {31 G-H3 , 844 Sensitivity, contact, mllru1e, inhibition by amiloride, 38 Sera

alopecia areata, 24S DEBR rat, 34S

Serine protease inhibi to rs. 379 Serum

-free epidermal culture model. 107 -treated corneocytes, 297

Severe a.lopecia arcata, 36S Sheath , outer root, of normal hair fo llicles, 12S Shope papillomas. 526 Sing le Parameter, O""ygenated Hemoglobin , C,Ul De Used to Quantify

Experunental Irritant-111dllced Inflammation, A , Kollias N, Gillies R., Muccilu jA, Uyeyama RK, Phillips SB , Drake LA. 421

Singlet oxygen , 68, 194

1038 SUBJECT AND T ITLE INDEX

oxygen- induced D NA damage, 68 Singlet O""ygen May Mediate the Ultraviolet A-Induced Synthesis of

Interstitial Collagenase, Wlaschek M , Briviba K. Stricklin GP, Sies H, Scharfetter-Kochan ek K, 194

SKALP/clafin, 189 Skin

adaptive responses in, 448 al1tigen-presenting ce lls in, 707 apoptosis-associated genes in, 78 appendages induction and growth, 71.1 cancer, 309, 883, 887 cultured human , fibroblasts, 503 direct imaging of molecular transport through, 142 disease(s)

HLA-linked,37S blistering, 982

effect of topica l tocopherol on UV radiation- mediated free radical damage on, 484

embryonic and fetal , 411 epithelial, tumors, nonfollicular, 396 grafts, 21S hairless mouse, edematogenic potential of phototherapy sources in, 359 hun1 3n

acute injury in , 479 cells, matrix-associated serine protease inhibitors fro m, 379 connective tissue-epitheli al junctions in , 90 inhibition of type I Sa-reductase in, 775 xenografts, 739

mouse hairless

free radicals in , 514 photoaged , 518

murine, 62 substitutes, cultured , 345 telogen mouse, 523

Small Proline-Rich Prote in.s Constitute a Multigene Family ofDiJferentiaJly H..egulated Cornified Cell Envelope Precursor Proteins, T he, Hohl 0, de Viragh PA, Amiguet-Barras F, Gibbs S, BackendcrfC, Huber M ,902

Society for Investiga tive Dermatology Abstracts, 554 Somatic gene therapy, 171. Specific Suppression of Lupus-Like Graft-Versus Host Disease U sing Ex­

tracorporea l Photochemical Attenuation of Effector Lymphocytes, Girardi M, H erreid P , T igelaar [lE, 177

Spectroscopy resonance

electron paramagne ti c, 514 13C-nuclear magne ti c, 806

Squamous cell carcinoma line, 33 Stem cell s, hair follicle, 38S StratUI11 Com CUI11

chymotryptic enzyme, 819 elastic properties of, 806 extracellular space, 819 human inner, 530

Stress, oxida tive, ability of cultured human keratinocytes to suppress, 355 Stroma of basal cell carcinoma. 509 Structure and Function of C utaneous N erves in Alopecia Arcata. Hordinsky

MK. Kennedy W. W endelschafer-Crabb G. Lewis S, 28S Structure-Fw1ction Ilelations in the Inhibition of Murine Contact H yper­

sensitivity by Amiloride, Lindgren AM, Granstein RD, H osoi J . GaUo IlL, 38

Summary of the Second In ternational l~esearch Workshop on Alopecia Arcata, Goldsmith LA, 2S

SW1 burn cell

formation, UV-induced , 287 partial involvement of TNF-a i11 the fo rma tion of, 922

-exposed epidermis, 928 Sunscreens and T4 N5 Liposom es Differ in T heir Ability to Protect Against

U ltraviolet-Induced Sunburn Cell Formation, Alterations of Den­dritic Epidermal Cells, and Local Suppression of Contact Hypersen­sitivity, Wolf 1', Cox, P, Yarosh DB, Kripke ML, 287

Superantigen-associa ted V (3 regions, 725 Superoxide anion production, 789

T I-IE JOURNAL OF INVESTIGATIV E DERMATOLOGY

Suppressive and Enhancing Effects of Ultravio let B R adiation on Expression of Contact Hypersensitivity in Man, Tie C, Golomb C. Taylor JR. Streilein JW , 18

Suprabasal KlIK10 keratins. 271. Sustained Production of Humal1 Transferrin by Transduced Fibroblasts

Implanted into Athymic Mice: A M odel for Somatic Gene Therapy, . Petersen MJ, Kaplan J, Jorgensen C M , Schmidt LA, Li L. Morgan

]H.., Kwan MK. Krueger GG, 171 SV 40 large T antigen, 755 Sweat gland development, 411 Synthesis of interstitial collagenase, 194

T

T-cell activation in skin, 995 adherence to keratinocytes, inhibition of by pentoxifyllu1e, 1004 lymphoma, cutaneous. 537, 889 receptor(s)

in chronic plaque-stage psoriasis , 725 repertoire V {3 in alopecia areata, 22S

vaccination, 177 TCR

beta-chain assembly, impaired , 537 s urf.~ce expression, 537

T-Cell H..eceptor R epertoire in C hronic Plaque-Stage Psorias is Is H..estricted and Lacks Enrichment of Superantigen-Associated V{3 R egions, BoelU1cke W-H, D resse l 0 , Manfras B . Zollner T M, W ettstein A, BolU11 BO, Stcrry W, 725 '

T-Cell Receptor R epertoire Vf3 in Alopecia Arcata, Szafer F, Price VH, Okscnberg JR, StcilU11an L, 22S

Telogcn mouse skin , 523 T etroxide , osmium and ruthaniium, 417 T4N5 liposomes, 287 TGF

-{31 , 118, 124, 260 -{31 mRNA, 750 IEGF-alpha-independent pathway, keratinocyte migration thro ugh, 729

Thcrapy m ethotrexa te, of psoriasis , 183 somatic gene, 171

Then11otolerance, 448 13C_nuclear magnetic resonance spectroscopy, 806 3T3 fibroblasts, 999 T h2-rype helper cell s, 350 Thymus gland , 25S TIMP, 384 Tisslle

inAammation, 350 inhibitor of metalloproteinases. 52 tumor, 509

T issue Inhibitor of MetaJloproteinases-1 Is Decreased and Activatcd Gela­tinases Are Incrcased in C hronic ·Wounds, Bullcn EC, Longaker MT, Updike DL, Benton R, Ladin 0, HOll Z , Howard EW , 236

T - lymphoma ce lls, 824 T lymphocytes , 11 TNF-a-induced T-Iymphoma ce ll adhesion to cndothel ioma ce lls, inhibi­

tion of, 824 Tocopherol, topical, 484 Topical

diphenylcyclopropenone. 36S FK506,523 immunotherapy in alopecia arcata children, 14S nutrients, 345 re tinoid efficacy and irritation, 779 tocopherol, 48

Topica l hnmwlOthcrapy in C hildren with Alopecia Areata, Orecchia G, Malagoli P, 35S

Topical Nutrients Promote Engraftment and Inhibit W ound Contraction of C ultured Skin Substitutes in AthY111ic Mice, Boyce ST, Supp AP. H arriger MD, G reenhalgh DG, Warden GO, 345

Topical Tretinoin Increases the Tropoelastin and Fibronectin Content of Photoaged Hairless Mouse Skin, Schwartz E, Kligman LH , 518

Trachyonychia, 27S Transcriptase-polyacrylamide chain reaction, - rcverse, 20S

VOL. 104. NO.6 J UNE 1995

T ranscriptional Regulation of In tercellu lar Adhes ion Molecule- 1: PMA­Induction Is Mediated by NFK.I3. Miiller S, Kammerbauer C, Simons U, Shibagaki N, Li L-J, Caughman SW, Degitz K, 970

Transdermall y delivered nicotine, 839 Transduced fibrob lasts, 171 Transfected keratinocytes. 277 Transferrin. human, production, 171 Transgenjc class II major 11istocompatibiljty genes in murine Langerhan s

cell s, 329 T ransglutaminase 1, 211 Transmission e lectron microscopy, 417 Treatment of Severe Alopecia Arcata with Topical D ipheny\cycloprope­

nOlle and 5% Minoxidjl: A C linica l and Immunopatho logic Eva lua­tio n, Shapiro J, Tan J , H o V, T ron V, 36S

Tretinoin , topica l, 518 Triple- helica l domain of type VII collagen, 438 T risphosphate. 1 , 4, 5-, in DJM celI s, 33 Tropoelasti n. 518 T umor(s)

hair-fo ll icle-derived, 396 necrosis f:lctor-a, 260. 318. 526. 922, 824, 856 non fo llicular epithelial skin, 396 tissue, 509

T unisia. comparative ep idemio logy of pemphjgus in France and, 302 12(R)-hydroxy-5 . 8, 14-eicosatrienoic acid, 47 Type

I co llagen , 750. 768 III co lIagen, 750 VII co llagen

gene CO L7Al , 803 triple- helica l domain , 438

Sa-reductase. 775

u U ltrastructural C hanges R esulting £i'om Kerati n-9 Gene Mutations in Two

Families with Epidermolytic Pa lmoplantar Keratoderma, N avsaria HA, Swcnsson O. Ratnave l R C . Shamsher M, McLean WHI. Lane EB, Grifl:iths WAD, Eady RAJ . Leigh 1M, 425

Ul trastructural Evidence fo r N erve Fibers WitI1in All Vital Layers of the I-hllnan Epidermis, Hi.!liges M. Wang L, J ohansson 0, 134

U ltrav io let DNA damage, 68 , 734 irradia tio n

contact hypersensitivity modulation by, 364 -ind uced changes in melanocytic nevi, 475 Ij ght-induced d,tmage, DNA repair capacity for, 933 melan ocyte survival and melanin synthesis enhancement. 859 sunburn cell formation, 287 T N F gene expression in response to, 318

radiation exposure to edematogenjc doses , 359 in the hairless mouse model , 51.8 - mediated free rad ica.! damage in skin, effect of topica.! tocopherol on,

484 U ltraviolet A

-ind uced lipid peroxidation, 964 synthes is of interstitia l collagenase, 194

Ultraviolet A 1, interI eukin- 10 production regulation by cultured human kerati.nocytes, 3

Ultra violet B in terIeukin-1 0 production regu lation by cul tured human keratinocytes, 3 radiation

contact hypersensitivi ty effects on expression of, 18 immunosuppression of, 364

- induced apoptosis of keratinocytes, 62. 922 U ltraviolet B-Induced Apoptosis of Keratinocytes: Evidence for Partial

Invo lvement of T umor Necrosis Factor-a in tile Formation of Sunburn Cells, Schwarz A, Bhardwaj R , Anlgane Y. Mahnke K, Rjemann H , Metze D, Luger TA. Schwarz T, 922

Ultrav io let ll-Induced Apoptosis of Keratinocytes in Murine Skin Is Reduced by Mild Loca l Hyperthermia, Kane KS. May ti n EV . 62

Ultrav iolet D-Induced Local ImmuJlosuppression of Contact Hypersensi­tiv ity Is Modulated by Ultravio le t IITadiation and Hapten Applica­tion, Miyauchi I-l , Horio T, 364

SUBJECT AND T ITLE INDEX 1039

Ultraviolet Irradiation Induces Acute C han ges in Melanocytic Nevi, T ron­nier M, Smo Lle J, Wolff HH, 475

Up-Regulation of Keratin 17 Expression in Human HaCaT Keratinocytes by In terferon- I', BOIU1ekoh B, Huerkamp C, Wevers A, Geisel j , Sebok D, Bange F-Ch, Greenhalgh DA, Bottger EC. Krieg T. Mahrle G, 58

Uroporphyrinogen decarbo>:"lase gene, 500 Urticaria pigmentosa, 101 Use of a Serum-Free Epidermal C ulture Model to Show Deleterious Effects

of Epidermal Growth Factor on Morphogenesis and Differentiation. C hen C-SJ, Lavker RM, Rodeck U, Risse B . Jensen PJ , 107

UV DNA damage, 68, 734 irradiation

contact hypersensitivity modulation by, 364 -induced changes in melanocytic nevi, 475 light-induced damage, DNA repair capacity for, 933 melanocyte survival and melanill syn thesis enhancement, 859 sunbum cell formation, 287 T NF gene expression in response to, 318

radiation exposure to edematogen.ic doses, 359 in the hairless mouse model, 518 -mediated free radical damage in skin, effect of topical tocopherol on,

484 VVA

-induced lipid pCI'oxidation, 964 syntIlCsis of interstitia l co llagenase, 194

UVA 1, interleukin-10 production regulation by cul[Ured human keratino­cytes, 3

uvn in terI cukin- l O production regulation by cul[Urcd human keratinocytes, 3 radiation

contact hypersensitivity effects on cxpression of, 18 inlnlunosuppressio n of, 364

- induced apoptosis of keratinocytes, 62, 922

v Vascular

endothelial growth factor expression of three major splice forms by human keratinocytes , 7 in human alopecia hair fo Lljcles, 18S

permeabili ty factor in bullous pemphigoid, 744 Vasodilata tion , axon-reflex-m cdiated, 872 V{3

superantigen-associated, regions, 725 T-ceLl receptor repertoire , 23S

Vitamin A, 224, 546 Vitiligo, 256 Vulgaris, pemphjgus

antigen, 720 autoantibodies, 323 reactivity with Dsgl, Dsg3 and desmoco\lins, 541

w Weber-Cockayne epidemlOlysis bullosa simplex. 877 WiUiam Montagna, Ph.D ., 161m Ie. Kligman AM. 444 Wound

clrronic. 236 contraction inhibition, 345 -edge keratinocytes. 479 hea ling, 199, 850

W uepper. Kirk D, M .D., l,iIJIIle, Hanifin JM . 446

Xenografts, human skin , 739 Xeroderma pigmentos uJ11 cells. 68

YeHow hair fo llicles, 792

x

y