study of mid-infrared light scattering due to skin for a non-invasive glucose monitor with an...

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Study of Mid-Infrared Light Scattering Due to Skin for a Non-Invasive Glucose Monitor with an Automated Setup Kevin A. Bors , Sabbir Liakat, Anna P. M. Michel, and Claire F. Gmachl

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Page 1: Study of Mid-Infrared Light Scattering Due to Skin for a Non-Invasive Glucose Monitor with an Automated Setup Kevin A. Bors, Sabbir Liakat, Anna P. M

Study of Mid-Infrared Light Scattering Due to Skin for a Non-Invasive Glucose Monitor with an Automated Setup

Kevin A. Bors, Sabbir Liakat, Anna P. M. Michel, and Claire F. Gmachl

Page 2: Study of Mid-Infrared Light Scattering Due to Skin for a Non-Invasive Glucose Monitor with an Automated Setup Kevin A. Bors, Sabbir Liakat, Anna P. M

• Quantum Cascade Lasers– More efficient energy solutions– Field testing– Good for developing countries

• Mid-Infrared Technologies for Health and the Environment

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MIRTHE and General Motivations for Research

Page 3: Study of Mid-Infrared Light Scattering Due to Skin for a Non-Invasive Glucose Monitor with an Automated Setup Kevin A. Bors, Sabbir Liakat, Anna P. M

Specific Motivation for Research

• Diabetes patients

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Example absorption spectrum of glucose

103

6

108

0

110

6

115

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Page 4: Study of Mid-Infrared Light Scattering Due to Skin for a Non-Invasive Glucose Monitor with an Automated Setup Kevin A. Bors, Sabbir Liakat, Anna P. M

Experimental Setup

• BARD (bi-axial rotation device)

• QCL (Quantum Cascade Laser)

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Page 5: Study of Mid-Infrared Light Scattering Due to Skin for a Non-Invasive Glucose Monitor with an Automated Setup Kevin A. Bors, Sabbir Liakat, Anna P. M

• Close-up of BARD setup

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Experimental Setup

Page 6: Study of Mid-Infrared Light Scattering Due to Skin for a Non-Invasive Glucose Monitor with an Automated Setup Kevin A. Bors, Sabbir Liakat, Anna P. M

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Program Capabilities

Variables Controlled by Program:• Axis of rotation• Range and precision

of angular movements of that axis

• Position of other axis• Range and Precision

of Wavenumber Movements

Page 7: Study of Mid-Infrared Light Scattering Due to Skin for a Non-Invasive Glucose Monitor with an Automated Setup Kevin A. Bors, Sabbir Liakat, Anna P. M

• Example scan using program

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Results of an Automated Scan Measuring Reflected Light as a Function of Position

Backscattered Light Intensity for Incidence φ=40°

Page 8: Study of Mid-Infrared Light Scattering Due to Skin for a Non-Invasive Glucose Monitor with an Automated Setup Kevin A. Bors, Sabbir Liakat, Anna P. M

Results of an Automated Scan Measuring Reflected Light as a Function of Position

• Light is Scattered by Dermis (Inner Layer of Skin)

• Glucose here proportional to level in blood

• Absorption Spectroscopy

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Page 9: Study of Mid-Infrared Light Scattering Due to Skin for a Non-Invasive Glucose Monitor with an Automated Setup Kevin A. Bors, Sabbir Liakat, Anna P. M

• Non-invasive glucose sensing• Automation of BARD

• Independent work

• Thanks to PEI, MIRTHE, and Professor Gmachl’s Group

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Summary, Future Work, and Acknowledgements