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  • STT520-420: BIOSTATISTICS ANALYSIS

    Dr. Cuixian ChenChapter 1: Introduction to Biostatistics AnalysisSTT520-420*

    STT520-420

  • EXAMPLES OF BIOSTATISTICSIs breastfeeding by HIV positive mothers associated with infant mortality?Is hormone replacement therapy associated with heart disease or stroke?Do patients taking Vioxx have an increasing risk of stroke?How are the MRI brain scans for schizophrenic patients different from people without the disease?

    STT520-420*

    STT520-420

  • EXAMPLES OF BIOSTATISTICSWhere do Biostatisticians work:1. Academic fields2. Government (e.g.: FDA)3. Non-profit organizations4. Pharmaceutical companies or Contracted Research Organizations (Local CRO PPD, Chiltern, Quintiles))

    STT520-420*

    STT520-420

  • THE ROLE OF BIOSTATISTICSBiology: Is the productivity and yield of maize significantly effected by the environment: drought, UV or both?

    Statistician: Designing studies for and analyzing data from agricultural experiments to increase productivity and yield.STT520-420*

    STT520-420

  • AVERAGE SALARY OF JOBS WITH RELATED TITLESFROM HTTP://WWW.INDEED.COM/SALARY/STATISTICIAN.HTML

    STT520-420*

    STT520-420

  • EXAMPLES OF BIOSTATISTICSTypical Activity of a Biostatistician:1. Sample size requirement2. Analysis plan at design stage3. Randomization4. Sampling design5. Statistical Analysis: Descriptive and inferential statistics analysis

    STT520-420*

    STT520-420

  • Biostatistics Courses requirementsBiostatistics Analysis/Survival Analysis (STT520/420);Design of Experiments and Analysis of Variance (STT511/411); Applied Regression and Correlation (STT512/412); Nonparametric Statistics (STT530/430);Categorical Data Analysis (STT525/425);Linear/Multivariate Models and Regression Analysis (STT540/440); Statistical Inference (STT566/466); Additional: Probability, Longitudinal Analysis, Generalized Linear Model;

    STT520-420*

    STT520-420

  • Typical Job duty of BiostatisticianDuty of Biostatistician:Write/review Statistical Analysis Plan (SAP).Write/review statistical section of protocol including sample size calculation, develop randomization schedule, mock up table shells/listing shells, provide specifications to programmers. Quality control the table from SAS programmer, and review listings. Validate deliverables.STT520-420*

    STT520-420

  • Typical Job duty of SAS programmerDuty for SAS programmer:Data validation: Data cleaning, Error checking.Build analysis database, based on the specifications from Biostatistician. Build table shells and listing shells for the Biostatistician to review and quality control. Require SAS Macro.

    STT520-420*

    STT520-420

  • Contract Research Organization (CRO)CRO = Contract Research OrganizationMost projects are the clinical trials from large pharmaceutical company.

    Local CRO:PPD; Quintiles; Kendle INC Research, and so on

    STT520-420*

    STT520-420

  • Biostatistician Job hunting websites:www.indeed.comwww.biospace.comwww.craigslist.orgOther websites:www.monster.comwww.careerbuilder.com

    http://monster.salary.com/SalaryWizard/Biostatistician-I-Salary-Details.aspxSTT520-420*

    STT520-420

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