structure and function of a viral dna gatekeeper bacteriophage spp1 portal protein the dodson...
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![Page 1: Structure and function of a viral DNA gatekeeper Bacteriophage SPP1 Portal protein The Dodson symposium Fred Antson, YSBL](https://reader033.vdocuments.mx/reader033/viewer/2022051618/56649d395503460f94a13e27/html5/thumbnails/1.jpg)
Structure and function Structure and function of a viral DNA of a viral DNA gatekeepergatekeeper
Bacteriophage SPP1
Portal protein
The Dodson symposiumThe Dodson symposium
Fred Antson, YSBLFred Antson, YSBL
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TRAP, trp RNA-binding attenuation TRAP, trp RNA-binding attenuation proteinprotein
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Structure and Structure and function of a function of a
viral DNA viral DNA gatekeepergatekeeper
Bacteriophage SPP1
Portal protein
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29SPP1
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D318
E323
D327
K331
E334D338K342
D348E352
E424
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ATPase
procapsid procapsid
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12
ATPase portal protein DNA
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SPP1 portal protein phi-29 portal protein
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V347
E424N421
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31 Å 21 Å
13-mer, X-ray 12-mer, EM/X-ray
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12
3
112114 5 6 7 8 9 10 1112 1
36°
28.8°
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Andrey Lebedev Andrey Lebedev University of YorkUniversity of YorkPhilippa SeaversPhilippa SeaversJoanne Turner Joanne Turner Miguel Ortiz-LombardiaMiguel Ortiz-LombardiaAlexey VaguineAlexey VaguineGuy DodsonGuy DodsonEleanor Dodson Eleanor Dodson
Paulo Tavares Paulo Tavares CNRS, Gif-sur-YvetteCNRS, Gif-sur-Yvette
Margret Krause Margret Krause MPI Genetik, BerlinMPI Genetik, Berlin Thomas TrautnerThomas Trautner
Elena Orlova Elena Orlova Birkbeck CollegeBirkbeck College
Juan Alonso Juan Alonso Centro National de Centro National de Biotecnologia, MadridBiotecnologia, Madrid
Acknowledgements