Association between the effectiveness of intervention and patients age

Age

90

80

70

60

50

40

30

20

score difference (after-before)

.3

.2

.1

0.0

-.1

-.2

Sex

female

male

*

15D-profiles in cataract patients before (green) and after (red) the operation as compared with age-adjusted normal population (blue)

Kaavio1

0.8440.82890.8415

0.88320.7730.9219

0.89080.91740.9174

0.82610.86030.8427

0.82990.80820.8154

0.98110.96970.9752

0.96710.95870.9622

0.84350.8520.8419

0.78320.80130.8176

0.84110.8770.8685

0.72350.77670.7743

0.87840.9060.8994

0.87630.89060.8963

0.80080.83830.8367

0.75870.79820.7809

15D-scorePopulation .8484before .8577after .8650

Vest

Kaihi ennen

Kaihi jlkeen

Dimensions

values

Sheet1

moveseehearbreathsleepeatspeechelimuactmentaldiscodeprdistrvitalsex

Vest0.8440.88320.89080.82610.82990.98110.96710.84350.78320.84110.72350.87840.87630.80080.7587

Kaihi ennen0.82890.7730.91740.86030.80820.96970.95870.8520.80130.8770.77670.9060.89060.83830.7982

Kaihi jlkeen0.84150.92190.91740.84270.81540.97520.96220.84190.81760.86850.77430.89940.89630.83670.7809

Sheet1

000

000

000

000

000

000

000

000

000

000

000

000

000

000

000

15D-lukemaVest .8484Kaihi ennen .8577Kaihi jlkeen .8650

Vest

Kaihi ennen

Kaihi jlkeen

Dimensiot

Tasoarvot

15D-profiilit ja -lukemat kaihipotilailla ennen ja jlkeen hoidon sek ik- ja sukupuolivakioidulla normaalivestll

Sheet2

Sheet3

*

Health related quality of life in patients with esophageal cancer

Kaavio1

0.91051739130.83

0.82597222220.83

0.739760.84

Radical surgery

Palliative treatment

Taul1

Statistics

MOVE1SEE1HEAR1BREATH1SLEEP1EAT1SPEECH1ELIM1UACT1MENTAL1DISCO1DEPR1DISTR1VITAL1SEX1D15SCORETMOVE1TSEE1THEAR1TBREATH1TSLEEP1TEAT1TSPEECH1TELIM1TUACT1TMENTAL1TDISCO1TDEPR1TDISTR1TVITAL1TSEX1TD15SCORKMOVE1KSEE1KHEAR1KBREATH1KSLEEP1KEAT1KSPEECH1KELIM1KUACT1KMENTAL1KDISCO1KDEPR1KDISTR1KVITAL1KSEX1KD15SCOR

NValid35353535353535353535353535353535232323232323232323232323232323236666666666666666

Missing00000000000000001212121212121212121212121212121229292929292929292929292929292929

Mean0.950.910.950.910.830.900.920.870.860.930.820.830.820.830.790.880.870.940.960.840.800.870.870.850.680.920.750.850.820.720.620.830.820.930.920.600.680.820.870.800.610.880.670.680.730.650.580.76

Median11110.76151111110.76510.72510.77130.70950.908111110.76151110.72110.7024110.77130.70950.830.85645110.587350.76150.8231110.5671510.70240.76510.72510.77130.575950.77085

Std. Deviation0.12453814340.17494416380.12272362860.16280596570.19502245480.20349067540.20787784040.17225656640.20541774420.14472244590.22139970440.15666119340.19648565030.1778628830.23256604410.09020657260.23142556760.12872670.0970046130.18497672340.22110105590.23443874820.22850356260.20441484050.28055839590.21597149830.19571485270.20523222930.23122816740.23002895860.3300626180.12124443350.21933700780.11154192040.12925436420.25540030340.24233131590.19378424080.30737013790.31200753840.2419647640.18414744820.31878601230.12925436420.23329244020.20127183360.14629669510.1530574271

Variance0.01550974920.03060546050.0150610890.02650578250.03803375790.0414084550.04321319650.02967232470.04219644960.02094458640.04901782910.02454272950.03860661080.03163520520.05408696490.00813722570.05355779330.01657056330.00940989490.03421638820.04888567690.05496152660.05221387810.0417854270.07871301350.04664368810.03830430360.04212026790.05346646540.05291332180.10894133180.01470021260.0481087230.01244160.01670669070.0652293150.05872446670.0375523320.09447640170.0973487040.0585469470.03391028270.10162452170.01670669070.05442536270.0405103510.0214027230.023426576

Skewness-2.6087305126-2.4833187461-2.559208006-1.5137100192-1.2008993992-2.4750166961-2.5019943781-0.9076250227-1.4369226547-1.5680171192-0.8310450007-0.9940755282-0.8118230242-0.5627395832-0.6647427667-0.8791627332-2.2486445836-2.3957820362-1.8430640439-0.5021312885-1.0467025517-2.0571582303-2.0351420407-1.0249301546-0.402233849-2.7682782916-0.2172807465-1.9328589727-1.4296075144-0.8444807366-0.2355956493-0.7304945856-0.6885018879-0.9682458366-0.96824583660.3773880013-0.5742920413-0-2.4494897428-0.96824583660.7627334289-0.9682458366-0.410032083-0.96824583660.0911814442-1.4493049402-0-0.1681521935

Std. Error of Skewness0.39769404430.39769404430.39769404430.39769404430.39769404430.39769404430.39769404430.39769404430.39769404430.39769404430.39769404430.39769404430.39769404430.39769404430.39769404430.39769404430.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.84515425470.84515425470.84515425470.84515425470.84515425470.84515425470.84515425470.84515425470.84515425470.84515425470.84515425470.84515425470.84515425470.84515425470.84515425470.8451542547

Kurtosis6.34485244266.4162866836.71894769851.00620825691.32731800227.17844887955.3756249171-0.34862558971.75560301180.4829545455-0.59874062232.41780282990.2926373789-0.8428253125-0.77971867270.26001522135.62446858296.04634817831.5218045113-1.14984496450.45108597814.87672679124.2365519146-0.0884167802-0.78610616876.8533940516-0.40865570854.9440696312.27938600130.6863133779-1.47211014520.1614469615-0.9373847888-1.875-1.8750.29689739530.2959666487-3.33333333336-1.875-0.6586241391-1.875-1.2027461711-1.875-1.8750.9375719529-3.3333333333-0.9768311717

Std. Error of Kurtosis0.77779439110.77779439110.77779439110.77779439110.77779439110.77779439110.77779439110.77779439110.77779439110.77779439110.77779439110.77779439110.77779439110.77779439110.77779439110.77779439110.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379881.74077655961.74077655961.74077655961.74077655961.74077655961.74077655961.74077655961.74077655961.74077655961.74077655961.74077655961.74077655961.74077655961.74077655961.74077655961.7407765596

Minimum0.47290.31370.46110.47710.30150.0710.24710.39580.21820.64340.3960.30530.26330.51520.24860.64780.0780.49010.74970.47710.30150.0710.12980.39580.07850.19560.3960.15760.12550.12530.13180.55040.47290.7840.74970.25810.30150.64620.24710.39580.41330.64340.20830.51480.47860.29570.44240.5391

Maximum11111111111111111111111111111110.995111111111110.765110.77130.70950.9581

MovingSeeingHearingBreathingSleepingEatingSpeechEliminationUsual activitiesMental functionDiscomfort and symptomsDepressionDistressVitalitySexual activity

0.950.910.950.910.830.900.920.870.860.930.820.830.820.830.79

0.870.940.960.840.800.870.870.850.680.920.750.850.820.720.62

0.820.930.920.600.680.820.870.800.610.880.670.680.730.650.58

15D score before treatment0.88

15D score3 months after treatment0.83

15D score 12 months after treatment0.76

Taul1

000

000

000

000

000

000

000

000

000

000

000

000

000

000

000

Before treatment

3 months after treatment

12 months after treatment

Taul2

0

0

0

Taul3

Statistics

THERAPIAMOVE1SEE1HEAR1BREATH1SLEEP1EAT1SPEECH1ELIM1UACT1MENTAL1DISCO1DEPR1DISTR1VITAL1SEX1D15SCORETMOVE1TSEE1THEAR1TBREATH1TSLEEP1TEAT1TSPEECH1TELIM1TUACT1TMENTAL1TDISCO1TDEPR1TDISTR1TVITAL1TSEX1TD15SCORKMOVE1KSEE1KHEAR1KBREATH1KSLEEP1KEAT1KSPEECH1KELIM1KUACT1KMENTAL1KDISCO1KDEPR1KDISTR1KVITAL1KSEX1KD15SCOR

radikaaliNValid23232323232323232323232323232323181818181818181818181818181818185555555555555555

Missing0000000000000000555555555555555518181818181818181818181818181818

Mean0.97708260870.89336521740.94392173910.97370434780.86593478260.93846956520.91677826090.93141304350.90170869570.93798260870.85652173910.82681304350.80310869570.85721739130.83885652170.91051739130.90691666670.9520.94437777780.82430.82751666670.85011111110.85417777780.82770.71768888890.90077777780.71746666670.84794444440.81712222220.71712777780.66774444440.82597222220.779740.91360.899880.581980.667380.858480.849420.758320.592180.857360.661340.664980.736460.624960.549240.73976

Median111111111110.76510.7251110.91991110.84880.880751110.72110.7024110.77130.70950.84510.7129110.47710.76151110.413310.70240.76510.72510.77130.44240.7033

Std. Deviation0.10990794760.20380058350.13585315250.08712266940.17100433970.13711638860.2029355360.13305933850.16363147870.13820153810.2198965190.16029016670.20785928790.17249829420.20518716030.06821393250.16298302420.09240320850.10707649580.19270524890.21271276750.25257648550.24840837710.21597733540.25418539530.24103173220.19278452460.22491159110.2525539140.24213078820.30569752110.12995623160.22367101510.11830807240.13709495610.28062723850.26750709710.19378424080.33670711610.33093396920.26405771530.1953178640.3559205220.13709495610.26077733410.21488694240.14629669510.1650944215

Variance0.0120797570.04153467780.01845607910.00759035950.02924248420.0188009040.04118283180.01770478750.02677526080.01909966510.04835447910.02569293750.04320548360.02975566150.04210177080.00465314060.02656346620.00853835290.01146537590.03713531290.04524672150.0637948810.06170672180.04664620940.06461021520.05809629590.03716587290.05058522380.06378347950.05862731860.09345097440.01688862210.0500287230.01399680.0187950270.0787516470.0715600470.0375523320.1133716820.1095172920.0697264770.0381490680.1266794180.0187950270.0680048180.0461763980.0214027230.027256168

Skewness-4.7958315233-2.2153986881-2.6046695088-3.1403996439-1.6157455264-1.8430640439-2.51747286-1.4678377789-1.5535181619-1.8430640439-1.2501049383-1.25202463-0.8540294843-0.8745337199-0.8511482315-0.7820469523-1.5359402095-1.4609882296-1.4609882296-0.4543302973-1.1253595808-1.9504734491-1.8640335353-0.8381585108-0.4127264077-2.355424929-0.0876181207-1.9440783688-1.4425727329-1.0016889354-0.4105418063-0.820718473-0.302162592-0.6085806195-0.60858061950.7222700242-0.3098379972-0.6085806195-2.2360679775-0.60858061951.1947433128-0.6085806195-0.3134087733-0.60858061950.0543880026-1.15964278410.60858061950.262429592

Std. Error of Skewness0.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.48133666150.5362778990.5362778990.5362778990.5362778990.5362778990.5362778990.5362778990.5362778990.5362778990.5362778990.5362778990.5362778990.5362778990.5362778990.5362778990.5362778990.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.9128709292

Kurtosis234.4588654696.85543452428.60544217693.98755701991.52180451135.74779699140.16063492061.94216551491.52180451130.22494311283.90677266530.4628055856-0.3214515549-0.59778148720.26474591591.39198247260.13660714290.1366071429-1.21490302110.66040935214.27942574473.3118248025-0.4947799386-0.90782580884.5718547122-0.12152403994.41553394761.88089695920.8967427573-1.18033095210.0068873902-1.2020144827-3.3333333333-3.33333333330.4569217369-0.4585428499-3.33333333335-3.3333333333-0.0275105096-3.3333333333-2.2831885543-3.3333333333-3.0023678472-0.2182394878-3.3333333333-1.1051299999

Std. Error of Kurtosis0.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379880.93476379881.03779508261.03779508261.03779508261.03779508261.03779508261.03779508261.03779508261.03779508261.03779508261.03779508261.03779508261.03779508261.03779508261.03779508261.03779508261.03779508262222222222222222

Minimum0.47290.31370.46110.69760.30150.64620.24710.68450.41330.64340.3960.30530.26330.51520.44240.73610.47290.7840.74970.47710.30150.0710.12980.39580.21820.19560.3960.15760.12550.12530.13180.55040.47290.7840.74970.25810.30150.64620.24710.39580.41330.64340.20830.51480.47860.29570.44240.5391

Maximum11111111111111111111111111111110.995111111111110.765110.77130.70950.9581

palliatiivinenNValid1212121212121212121212121212121255555555555555551111111111111111

Missing0000000000000000777777777777777711111111111111111111111111111111

Mean0.900.950.960.790.760.830.910.770.770.910.750.840.840.760.700.830.760.901.000.880.720.930.940.940.531.000.880.860.840.710.440.831.001.001.000.700.760.651.001.000.7210.700.770.730.770.710.84

Median1110.69760.7615110.68450.72110.70240.76510.862550.77130.70950.864611110.76151110.4133110.76510.72510.77130.24860.82461110.69760.76150.6462110.72110.70240.76510.72510.77130.70950.8384

Std. Deviation0.14135826820.09768967560.09742914290.20424640870.22628002560.28737421070.2262509240.19130317420.25373968570.16127841820.21621183780.15590245690.17842024170.17916717180.26340089910.10675853380.40003932560.228034212300.16563130140.25429795520.15822417010.13268827380.14109588940.349412645700.16300223310.12866002880.15056893110.20457496180.39138999480.0951873836

Variance0.019982160.00954327270.00949243790.04171659550.051202650.0825839370.05118948060.03659690450.06438382810.02601072820.04674755880.02430557610.03183378270.03210087550.06938003360.01139738450.1600314620.05199960200.0274337280.064667450.0250348880.0176061780.019908050.12208919700.0265697280.0165534030.0226710030.0418509150.1531861280.009060638

Skewness-0.8124038405-1.3266499161-2.0552372126-0.1865770343-0.6910389189-1.9666220339-2.7986857565-0.0436288021-1.018555227-1.3266499161-0.2989023859-0.5219637245-0.6207822723-0.137417345-0.2261777047-0.2972774103-1.7726017296-2.2360679775-0.6085806195-1.2404547974-2.2360679775-2.2360679775-2.23606797750.2205107564-0.60858061950.60858061950.60858061950.37740337350.84541590030.7013279052

Std. Error of Skewness0.63730200550.63730200550.63730200550.63730200550.63730200550.63730200550.63730200550.63730200550.63730200550.63730200550.63730200550.63730200550.63730200550.63730200550.63730200550.63730200550.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.91287092920.9128709292

Kurtosis-1.65-0.32592592592.64-1.403055791-0.10766840794.02913214387.9079944077-0.3768007330.6324718326-0.3259259259-0.6355387175-0.0867232094-0.5947825675-0.8505003792-1.1756046028-0.84488263352.94799344015-3.33333333332.841350053555-0.2497244126-3.3333333333-3.3333333333-3.3333333333-0.9938153832-1.56375839952.1161029023

Std. Error of Kurtosis1.23224647391.23224647391.23224647391.23224647391.23224647391.23224647391.23224647391.23224647391.23224647391.23224647391.23224647391.23224647391.23224647391.23224647391.23224647391.23224647392222222222222222

Minimum0.71290.7840.74970.47710.30150.0710.24710.39580.21820.64340.3960.51480.47860.51520.24860.64780.0780.490110.69760.30150.64620.70330.68450.078510.70240.76510.72510.51520.13180.71061110.69760.76150.6462110.72110.70240.76510.72510.77130.70950.8384

Maximum11111111111111111111111111111110.97641110.69760.76150.6462110.72110.70240.76510.72510.77130.70950.8384

radikaali

MovingSeeingHearingBreathingSleepingEatingSpeechEliminationUsual activitiesMental functionDiscomfort and symptomsDepressionDistressVitalitySexual activity

0.980.890.940.970.870.940.920.930.900.940.860.830.800.860.84

0.910.950.940.820.830.850.850.830.720.900.720.850.820.720.67

0.780.910.900.580.670.860.850.760.590.860.660.660.740.620.55

Radical surgeryPalliative treatment

15D score before treatment0.910.83

15D score 3 mo after treatment0.830.83

15D score 12 mo after treatment0.740.84

palliatiivinen

MovingSeeingHearingBreathingSleepingEatingSpeechEliminationUsual activitiesMental functionDiscomfort and symptomsDepressionDistressVitalitySexual activity

0.900.950.960.790.760.830.910.770.770.910.750.840.840.760.70

0.760.901.000.880.720.930.940.940.531.000.880.860.840.710.44

1.001.001.000.700.760.651.001.000.7210.700.770.730.770.71

Lhttaso

MovingSeeingHearingBreathingSleepingEatingSpeechEliminationUsual activitiesMental functionDiscomfort and symptomsDepressionDistressVitalitySexual activity

Radical surgery0.980.890.940.970.870.940.920.930.900.940.860.830.800.860.84

Palliative group0.900.950.960.790.760.830.910.770.770.910.750.840.840.760.70

Taul3

0.97708260870.90691666670.77974

0.89336521740.9520.9136

0.94392173910.94437777780.89988

0.97370434780.82430.58198

0.86593478260.82751666670.66738

0.93846956520.85011111110.85848

0.91677826090.85417777780.84942

0.93141304350.82770.75832

0.90170869570.71768888890.59218

0.93798260870.90077777780.85736

0.85652173910.71746666670.66134

0.82681304350.84794444440.66498

0.80310869570.81712222220.73646

0.85721739130.71712777780.62496

0.83885652170.66774444440.54924

Before treatment

3 months after treatment

12 months after treatment

Before treatment

3 months after treatment

12 months after treatment

Radical surgery

Palliative treatment

00

00

00

00

00

00

00

00

00

00

00

00

00

00

00

Radical surgery

Palliative group

*

Conclusionsa systematic measurement of effectiveness and cost-effectiveness should be mandatory in the futuredata feeding should be automatic (EPR)follow-up should be extended to yearsinformation gained should start guiding allocative (political) decisions

*

Evaluation, the missing ingredientto be evaluated, examples:practices: pharyngeal tonsillectomyservice provision: private off-hour activitiesallocation: 15-D measures as guidesskills: MDs and managementdivision of labor: nurse practitionersICT: still a paradox or something more?

*

Endpiecemissing: a new strong culture, wherethe future vision is clear and shared by all counterpartscontracting systems are modern measuring instruments are in place and usedgood performance is rewardednothing is done without evaluationthus far most of this is lacking...