BEHAVIOR GENETICS ASSOCIATION 28T" ANNUAL MEETING STOCKHOLM, SWEDEN JUNE 1998

STOCKHOLM BEAUTY ON WATER

BEHAVIOR GENETICS ASSMATIoN The purpose of the Behavior Genetics Association is to promote scientific study of the interrelationship of genetic mechanisms and behavior, both human and animal; to encourage and aid the education and training of research workers in the field of behavior genetics; and to aid in the dissemination and interpretation to the general public of knowledge concerning the interrelationship of genetics and behavior, and its implications for health and human development and education.

For additional information about the Behavior Genetics Association, please contact Dr. Andrew Heath, BGA Secretary, Department of Psychiatry, Washington University School of Medicine, Box 8134, 4940 Children's Place, St. Louis, MO 63110.

EXECUTIVE COMMITTEE 1997-1998 1998-1999 President President-Elect Past President Secretary Treasurer Member-at-Large Member-at-Large Member-at-Large

Nicholas Martin Norman Henderson James Wilson Andrew Heath Matt McGue Linda Dixon Nancy Pedersen Deborah Finkel

Norman Henderson Richard Rose Nicholas Martin Hermine Maes Matt McGue Nancy Pedersen Deborah Finkel Irwin Waldman

Presidents YEAR Dobzhansky Awardees

Thompson Awardees Local Hosts

1972-1973 Th. Dobzhansky 1973-1974 John L. Fuller 1974-1975 Gerald E. McClearn 1975-1976 J. P. Scott 1976-1977 Irving I. Gottesman 1977-1978 W. R. Thompson 1978-1979 Lee Ehrman 1979-1980 V. Elving Anderson 1980-1981 John C. Loehlin 1981-1982 Norman D. Henderson 1982-1983 John C. DeFries 1983-1984 David W. Fulker 1984-1985 Steven G. Vandenberg 1985-1986 Sandra Scarr 1986-1987 Ronald S. Wilson 1987-1988 Peter A. Parsons 1988-1989 Leonard L. Heston 1989-1990 Robert Plomin 1990-1991 Carol B. Lynch 1991-1992 Lindon J. Eaves 1992-1993 David A. Blizard 1993-1994 Thomas J. Bouchard, Jr. 1994-1995 Glayde Whitney 1995-1996 James Wilson 1996-1998 Nicholas Martin

1971 1972 1973 1974 1975 1976 1977 1978 1979 1980 1981

1982 1983 1984

Steven Vandenberg Elliott Slater Ernst Caspari Benson Ginsburg Sheldon Reed

Gardner Lindzey Peter Broadhurst Leonard Heston

1985 Nikki Erlenmeyer-Kimling

1986 1987 1988 1989 1990

1991

1992 1993.

1994

1995

1996

1997 1998

Raymond Cattell J L Fuller & J P Scott Lee Erhman Gerald McClearn Irving Gottesman

John Loehlin

John DeFries Peter Parsons Aubrey Manning

David Fulker

Ron Johnston

Nancy Galvin Gregory Carey Marla Sokolowski

Michael Pogue-Geile

Paul Sharp Mike Neale Christine Michard & George Vogler Dorret Boomsma & Lucinda Miner David Harder J. S. de Belle Joanne Meyer Susan Parlour Lon Cardon & Philip Welbergen Abel Bult & Lawrence Rodriguez Deborah Finkel Hermine Maes Frans Sluyter

Soo HyunRhee & Stephen Petrill Stephanie Schmitz

Martine Thomas

R Osborne/B Ginsburg - Storrs CT GE McClearn - Boulder CO WS Pollitzer - Chapel Hill NC S Scarr - Minneapolis MN J Bruell - Austin TX JC DeFries - Boulder CO R Wilson - Louisville KY T Klein - Davis CA C Lynch - Middletown CT RD Bock - Chicago IL L Erhman - Purchase NY Rose/Guttman/Guttman - Jerusalem D Nash - Ft Collins CO D Fulker - London R Rose - Bloomington IN

G McClearn - State College PA

G Ashton/R Johnson - Honolulu HI L Heston - Minneapolis S Kerbusch - Nijmegen, Netherlands S Scarr - Charlottesville VA P Roubertoux - Aussois, France

G Vogler - St Louis MO

J Wilson - Boulder CO N Martin - Sydney, Australia A Fernandez-Teruel/RM Escorihuela/ A Tobena - Barcelona J Meyer/L Eaves - Richmond VA

G McCleam/G Vogler/D Blizard/ B Jones - Pittsburgh PA Tony Vernon - Toronto, Canada Nancy Pedersen - Stockholm, Sweden

BEHAVIOR GENETICS ASSOCIATION 28th Annual Meeting

Salenhuset Stockholm, Sweden

June 8-10, 1998

BEHAVIOR GENETICS ASSOCIATION La- 28th Annual Meeting Akul

1.-G4^ bt.ko-

Liotik Walt- The 28th Annual Meeting will be held at Salen Konferens & Matsalar (Salen's Conference and Restaurant Center) in

Stockholm. The meeting will start after lunch on Monday with a plenary session, and then parallel sessions as usual. Monday evening we will meet at the Stockholm City Hall at 6 pm for a tour and a complementary buffet dinner. No activities are planned for Tuesday evening. The meeting will conclude with the banquet on Wednesday to be held at the Vasa Museum. (See home pages: http://www.vasamuseet.se and http://www.stockholm.se/).

Salen's is located in the center of Stockholm, with restaurants, department stores, banks, post office, theaters, opera, and the concert hall a short walk away. The main entrance is at Norrlandsgatan 15; an alternative entrance from a parallel street where one can take a city bus is Regeringsgatan 48.

The 9th International Congress on Twin Studies will be held in Helsinki June 4-6. Many of you may want to take this opportunity to visit Helsinki first and then Stockholm. Stockholm is the Cultural Capital of Europe for 1998. Be sure to make your reservations early.

Monday, June 8

10:00am

11:00am - 5:00pm

1:00pm - 2:00pm

Executive Committee Meeting I

Registration

HOW TO GET TO STOCKHOLM: American Airlines has direct non-stop flights from Chicago; SAS has direct flights from Newark. For those attending the Twin Congress in Helsinki prior to BGA, it is possible to get a circle ticket -- USA 4 Helsinki 4 Stockholm 4 USA for not so much more than a round-trip between US and Stockholm. Both SAS and Finnair fly between Helsinki and Stockholm.

Viking Line and Silja Line ferries leave Helsinki at 6 pm every day, and arrive in Stockholm at 8:30 or 9 am the next morning. Because there will be only a few hours of darkness that time of the year, the ride through the Finnish and Swedish archipelagos will be spectacular.

ARRIVAL IN STOCKHOLM: Arlanda Airport Stockholm (26 miles, 41 kilometers) By taxi: There are fixed-price taxis to Stockholm with different rates from different companies+ 345 Swedish crowns

being the cheapest at this time. The price is usually displayed on the side of the taxi. Be sure that you and the driver agree on a price before you get into the taxi.

By airport bus and taxi: Airport buses leave Arlanda for Stockholm City Terminal (above the Central Station) every 10 minutes from 6:25 am until 11:00 pm for a price of 60 Swedish crowns one way. When you get on the bus, tell the driver that you will want a taxi from City Terminal. The taxi price will be about 80 crowns to your hotel - cheaper than getting your own taxi from the City Terminal. Hotels and the conference center are a short taxi ride from City Terminal. (Be sure the bus is going to Stockholm City Terminal. There are several similar-looking buses going to different parts of Stockholm.)

From Viking ferry: Taxi to the hotels or Salens cost about 80 crowns. One can take the Viking Line bus (20 crowns) which runs continuously from 9.15 am from the boat to Slussen. From Slussen one can 'take a taxi or bus number 46, 55, or 59 to Norrmalmstorg and walk. Buses within the city cost 14 crowns.

From Silja Line Ferry: Buses run from the boat to the subway station at Ropsten continuously. Take subway to the Ostermalmstorg station. Walking distance is 5-10 minutes from there to the conference center.

Stockholm residents are quite helpful! Ask anyone for directions.

Plenary Session: LISREL and Twin Models Karl G. Jtireskog & Stefan Mattson, Uppsala University Introduced by Nick Martin

Aulan

2:00pm - 2:30pm Coffee Break Caret

2:30pm - 4:45pm Symposium I: A New Generation of Longitudinal Twin Studies of Behavioral Development Organizer: Hill Goldsmith

Getting around in Stockholm: It is possible to walk to Salens from the hotels, and even from the youth hostel. One can buy a strip of 20 coupons for 95 Swedish crowns which can be used for unlimited travel on city subway, bus and rail services. Buses within Stockholm cost 14 crowns or 2 coupons from a strip. You can travel for 1 hour, including transfers, on the 2 coupons. Or, one can buy a 1-day Stockholm Tourist Card for 60 crowns or a 3 day card for 120 crowns giving unlimited travel on city transportation. There is also a Stockholm card (18 crowns for 1 day, 350 crowns for 2 days and 470 crowns for 3 days) which gives entrance to museums in addition to transportation.

Bus 43 (which connects with both buses 65 from the youth hostel and 47 from Central Station) passes Salen's back entrance on Regeringsgatan--get off at bus stop called Oxtorgsgatan and walk back a few steps. Ask the driver to tell you where to get off.

For ongoing updated information about the conference itself, please access the conference web site: http://www.bga.org/1998

2

The Wisconsin Twin Panel: Temperament in context. Hill Goldsmith & Kathryn S. Lemery

Aulan

Preliminary results from the twins' early development study: Language delay and mild mental retardation in infancy. Thalia C. Eley & The Twins' Early Development Study

The Netherlands Twin Register. Dorret I. Boomsma

The Georgia Twin Registry: Sample description and research issues. Irwin D. Waldman, Soo Hyun Rhee, Sarah A. Feigon & Jessica L. Bar

Risk factors for aggression and antisocial behavior in twins Laura A. Baker & Adrian Raine

6:00pm - 8:00pm Reception (Swedish Buffet) City Hall

3

Tuesday, June 9

9:00am - 10:30am Symposium II: Contributions from Finnish Twin Studies: Ongoing Finnish Twin Cohort Studies in Behavioral Genetics Organizer: Richard J. Rose

Aulan

Introduction: Historical contributions from Finnish twin studies to behavior genetics R. J. Rose

Parasomnias among adult finnish twins. J. Kaprio, C. Hublin, M. Partinen, K. Heikkila & M. Koskenvuo

Social support, life-events, and vulnerability to depression among 12,063 adult twins. K. Romanov, J. Varjonen, J. Kaprio & M. Koskenvuo

Peers, teachers, and parents as raters of twins' behavioral and emotional problems and adjustment. Lea Pulkkinen, Jaakko Kaprio & Richard J. Rose

Genes, environments, and precursors of alcoholism: Finnish twin family studies. Richard J. Rose, J. Kaprio, L. Pulkkinen, R .J. Viken & M. Koskenvuo

Migrant-discordant twins: A natural experiment on effects of environmental change. Niklas Hammar, J. Kaprio, L. Alfredsson, M. Koskenvuo, T. Riinnemaa, T. Hammar, U. Hagstriim & L. Viikari

10:30am - 11:00am Coffee Break Cafet

11:00am - 12:00pm Symposium II: (continued) Aulan

12:00pm - 1:30pm Lunch

1:30pm - 3:00pm Paper Session I: Reading and Attention Deficit Disorders Aulan Chair : J.C. DeFries

1 : 30 Linkage studies suggest a possible locus for dyslexia near the Rh region oh chromosome 1. E. L. Grigorenko, F. B. Wood, M. S. Meyer, J. E. D. Pauls, L. A. Hart & D. L. Pauls

1:45 Quantitative trait locus for specific language and reading deficits on chromosome 6p. Javier Gayan, S. D. Smith, S. S. Cherny, L. R. Cardon, D. W. Fulker, W. J. Kimberling, R. K. Olson, B. F. Pennington & J. C. DeFries

4

2:00

2 : 15

2:30

2 : 45

1:30pm - 3:00pm

1 : 30

1: 45

2:00

Testing psychological theories of hyperactivity within a twin study. Jonna Kuntsi & Jim Stevenson

Sex differences in the etiology of inattention and hyperactivity/impulsivity. Soo Hyun Rhee, Irwin D. Waldman, David A. Hay & Florence Levy

Genetic validation of the DSM-IV subtypes of ADHD. David A. Hay, M. McStephen, I. Waldman & F. Levy

Genetic and environmental associations between attention problems and other problem behaviors. Stephanie Schmitz & David W. Fulker

Paper Session II: Philosophical and measurement issues Olympia Chair : A.C. Heath

Philosophy of human behavior genetics. S. Wieder

Genes and environment: A new theory of freedom. Mark Ast

Twins' ratings on the "Sibling Inventory of Differential Experience" (SIDE): A three-year follow-up study. Ruth Guttman & Nitzan Goldschmidt

2 : 15 Discrepancies in life event reports with multiple raters and multiple time points. J. M. Lessem, J. K. Hewitt, L. J. Eaves, J. L. Silberg, M. Rutter & E. Simonoff

2:30 Iris patterns and personality: Does a relationship exist that can be useful for the Five Factor Model and behavioral genetics?. (25 min. paper) Mats Larsson

3:00pm - 3:30pm Coffee Break and Poster Session I (with authors) : Cafet/Lobby

1. Genetic influences on personal assessments of stressful situations. Andreas Busjahn, Hans-Dieter Faulhaber & Friedrich C. Luft

2. Differential genetic etiology of reading disability as a function of IQ. S. J. Wadsworth, R. K. Olson, B. F. Pennington & J. C. DeFries

3. Discrimination of odor differences in MHC-deficient mice. Kunio Ytmazaki, G.K. Beauchamp, J. Bard & E.A. Boyse

4. Update on IQ similarity of unrelated same age siblings. Nancy L. Segal

5

5.

6.

7.

8.

9.

10.

A genetic analysis of the relationship between low academic performance and early-onset substance use in adolescent males. L.N. Legrand, Matt McGue & W.G. Iacono

A study of genetic and environmental influences on prosocial and antisocial behaviours. Christine Pett & Jim Stevenson

The Y chromosome, sexual behavior and pregnancy block in Mus Musculus. Tara L. McLaughlin & Benson E. Ginsburg

Obstetrical complications in twin pregnancies. Joan T. Bihun, Jackie S. Roessler & H. Hill Goldsmith

Using discordant sibling pairs to replicate behavioral associations within families. J. K. Johnson, R. J. Viken, & R. J. Rose

Do genetic and environmental influences on childhood conduct disorder vary across environmental contexts? Jessica L. Bar, Irwin D. Waldman, David A. Hay & Florence Levy

11. Home cage activity in mice selected for high- and low open-field ambulation Norman D. Henderson, Theresa Tritto, David W. Fulker, and John C. DeFries.

12. Genetic disposition for global maturity: an explanation for genetic effects on parental reports of ADHD 3. Brigitta Steffensson, Jan-Olov Larsson, Ingegard Fried, Eman ElSayed, Per-Anders Rydelius, and Paul Lichtenstein

3:30pm - 5:00pm

3:30

3:45

Paper Session III: Cognition Aulan Chair : D. Finkel

Sources of individual variation contributing to change in cognitive abilities. Chandra A. Reynolds, Margaret Gatz & Nancy L. Pedersen

Common genetic influences on general cognitive ability in males and females: A twin study. Valerie S. Knopik & John C. DeFries

4:00 Genetic and environmental influences on the relationship between attachment to family and attachment to school. Kristen C. Jacobson & David C. Rowe

4 : 15 IQ and academic achievement in twins: A longitudinal study. Marcie Chambers & D. W. Fulker.

4:30 Is there a genetic basis for sex differences in social cognition?. Jim Stevenson

6

I

4:45 Genetics of early cancer detection behaviors in Australian female twins. Susan A. Treloar, Christine McDonald & Nicholas G. Martin

3:30pm - 5:00pm

3 : 30 Etiological validation of a developmental taxonomy of antisocial behavior. Irwin D. Waldman, David A. Hay & Florence Levy

3:45

Paper Session IV: Bio-social Factors Olympia Chair : Steve Maxson

4:00

4:15

The heritability of personality factors in zoo chimpanzees Pan Troglodytes. Alexander Weiss & J.E. King

Developmental genetic analysis of conduct disorder in adolescent twins. Hermine H. M. Maes, Michael C. Neale, Judy L. Silberg, Lindon J. Eaves

Developmental isolation and subsequent adult behavior of Drosophila Paulistorum: Courtship. Lee Ehrman & Y.-K. Kim

4:30 Psychophysiology and genetics in twins. Laura A. Baker

4:45 Alcohol preference in mice: Replication using genotypic selection and an F4 advanced intercross. Lisa M. Tarantino & Gerald McClearn

EVENING FREE

7

Wednesday, June 10

9:00am - 10:30am Symposium III: The Longitudinal OCTO-Twin Study: The Etiology of Cognitive Functioning and Health-Related Behaviors in the Oldest-Old Organizers: Boo Johannson and Stephen A. Petrill

Aulan

2 : 15 Gene mapping in the presence of gene-environment interactions. Alexandre A. Todorov, E. Genin, K. D. Siegmund, P. A. F. Madden & A. C. Heath

2:30 New models for survival studies of twins. Anatoli I. Yashin, I.A. Iachine & A.S. Begun

2: iklihood ods of ass Ful r &

who and linkage Sham

Overview of the OCTO-Twin Study Gerald E. McClearn

Stability and change in cognitive functioning in late adulthood. Scott M. Hofer, S. Berg, B. Johansson & G. E. McClearn

3:00 The effects of randomized response on the power of the classical twin study. M. C. Neale

3:15pm - 3:45pm Coffee Break and Poster Session II CafeeLobby

Extremes in cognitive functioning in the oldest-old: A Defries-Fulker analysis of non-demented octogenarian twins. Stephen A. Petrill, Boo Johansson, Stig Berg, Robert Plomin & Gerald E. McClearn

Cognitive impairment and dementia in the oldest old twins. Boo Johansson, Birgitta Andersson, David Karlsson & Gerald E. McClearn

Genetic and environmental influences on health-control beliefs in the oldest-old. Julia D. Grant, Boo Johansson & Gerald E. McClearn.

1.

2.

Differential twin-spouse phenotypic assortment, not social homogamy. Kay Phillips

Sex-limited genes and individual differences in femininity-masculinity as assessed by the Fern content scale of the MMPI. Richard J. Viken, Richard J. Rose, Jaakko Kaprio & Markku Koskenvuo

3. Pubertal timing and personality predict alcohol use within adolescent female twin pairs. Danielle M. Dick, Richard J. Rose, J. Kaprio & R. J. Viken

Discussant: Matt McGue

10:30am - 11:00am Coffee Break

11:00am - 12:00pm Symposium III (Continued)

12:00pm - 1:30pm

1:30pm - 3:15pm

1.30

4.

Cafes

Aulan

Lunch

5.

6.

7.

Paper Session V: Quantitative Methods and M9dels Chair : JrifeNtrArdle Pi0/04-eA.--

/ Monozygotic twins increase power of genetic association studies of complex phenotypes. Michael B. Miller

Olympia

Genetic and environmental influences on childhood anxiety disorder symptoms and their moderation by age and sex. Sarah A. Feigon & Irwin D. Waldman

Assortative mating for MMPI-2 personality traits in a sample of parents of twins. Susan L. Trumbetta & Kay Phillips

A twin study of stability and change in late-life cognitive functioning. Matt McGue & Kaare Christensen,

8.

1:45 Measurement models for sexual orientation in a large Australian twin sample. N. G. Martin, K. Kirk, M. P. Dunne & J. M. Bailey

Spouse and familial similarity for alcohol use and alcohol-related problems in a Mauritian sample. Chandra A. Reynolds, Adrian Raine, Kjetil Melligen, Peter H. Venables & Sarnoff A. Mednick

The familial aggregation of nicotine, alcohol and marijuana dependence symptoms in families with substance-abusing adolescent probands and controls. Michael C. Stallings, S. E. Young, D. R. Miles, J. K. Hewitt, D. W. Fulker & T. J. Crowley

Psych athy in a twin sample of alcohol dependent twi and their co- s. *denour,, A.C. Heath, K.K. Bucholz, P.A.F. Ma en & N.G(. Ma n.

2 : 00 Modeling the genetic contribution to smoking and other substance use disorders: Quantitative genetic approaches. A. C. Heath, P. A. F. Madden, A. Todorov & N. G. Martin

8 9

10. Family factors underlying conduct disorder and attention deficit hyperactivity disorder: A sibling study of comorbidity. Susan E. Young, M. C. Stallings, R. P. Corley, J. K. Hewitt & D. W. Fulker

11. Twin study of self-recognition in toddlers. Paula Y. Mullineaux, Deborah Finkel & Adam P. Matheny

3:45pm - 5:15pm Paper Session VI: Substance Use and Dependence Olympia Chair: G.E. McClearn

3:45 Personality and the common genetic risk for conduct disorder and alcohol dependence. Wendy S. Slutske, A. C. Heath, P. A. F. Madden, K. K. Bucholz, S. H. Dinwiddie, M. P. Dunne, D. J. Statham & N. G. Martin

4:00 Genetic and environmental influences on adolescent drug and alcohol use in the Colorado Adolescent Twin Study (CATS). Steven M. Wilson & John K. Hewitt

4:15 The prediction of peer substance use during adolescence: Evidence for shared environmental influences. Julia D. Grant, Kathleen K. Bucholz, Pamela A. F. Madden, Wendy, S. Slutske & Andrew C. Heath.

Geneti Colo ado A Ste en M.

homas P.

a environmental it s o adolesce nd a 1 use in the olesce in Study ( ATS)

so , , J A u K. Hewitt Robi P. Corley, < e . Sta ford

4:45 Genetics influences on early stages in cigarette smoking in Missouri adolescent female twins. Pamela A.F. Madden, K.K. Bucholz, L.J. Bierut, W.S. Slutske, W. Reich & A.C. Heath

5:00 Multivariate genetic analyses of alcohol, tobacco, and,marijuana con tion and depedence among female twins from the MCV Stre,srs & ping Tw n Pro t Car II A. Prescott & Kenneth S. Kendler

5:30pm - 6:30pm Business Meeting

7:30pm-11:00pm

Olympia

Banquet and Awards (boat to museum leaves at 7:30pm) Vasa Museum

Thursday, June 11

9:00am Executive Committee Meeting II Journalisten 10

NOTES

Monday, June 8

11:00am - 5:00pm

10:00am

1:00pm - 2:00pm

2:00pm - 2:30pm

2:30pm - 4:45pm

6:00pm - 8:00pm

Tuesday, June 9

9:00am - 10:30am

10:30am - 11:00am

11:00am - 12:00pm

12:00pm - 1:30pm

1:30pm 3:00pm

1:30pm 3:00pm

3:00pm 3:30pm

3:30pm 5:00pm

3:30pm - 5:00pm

EVENING FREE

Wednesday, June 10

9:00am - 10:30am

10:30am - 11:00am

11:00am - 12:00pm

12 :00pm - 1:30pm

1:30pm - 3:15pm

3:15pm - 3:45pm

3:45pm - 5:15pm

5:30pm - 6:30pm

7:30pm - 11:00pm

Thursday June 11

9:00am

Behavior Genetics Association 28th Annual Meeting Stockholm, Sweden June 8 - 11, 1998

Program Overview

Registration

Executive Committee Meeting I

Plenary Session: LISREL and Twin Models

Coffee Break

Symposium I: A New Generation of Longitudinal Twin Studies

Reception

Symposium II: Contributions from Finnish Twin Studies

Coffee Break

Symposium II: (continued)

Lunch

Paper Session I: Reading and Attention Deficit Disorders

Paper Session II: Philosophical and measurement issues

Coffee Break and Poster Session I

Paper Session III: Cognition

Paper Session IV: Bio-social Factors

Symposium III: The Longitudinal OCTO-Twin Study

Coffee Break

Symposium III (Continued)

Lunch

Paper Session V: Quantitative Methods and Models

Coffee Break and Poster Session H

Paper Session VI: Substance Use and Dependence

Business Meeting

Banquet and Awards (boat to museum leaves at 7:30)

Lower Lobby

Journalisten

Aulan

Cafet

Aulan

City Hall

Aulan

Cafes

Aulan

Aulan

Olympia

Cafet/Lobby

Aulan

Olympia

Aulan

Cal&

Aulan

Olympia

Cafet/Lobby

Olympia

Olympia

Vasa Museum

Executive Committee Meeting II Journalisten