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    Using Office BasedSpirometry to Improve

    Asthma Outcomes

    Henry A. Wojtczak, [email protected]

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    All Too Common!!

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    Asthma Stakeholders

    Patient with asthma

    Parents, legal guardians, relatives, older siblings

    Population Health and Disease Managers

    Primary Care Team Provider ( MD, PA, NP)

    Nurse Respiratory Therapist

    Pharmacist

    Case Manager

    Social Worker

    School / Preschool / Daycare staff Teacher / teachers aide Nurse

    Coach

    BUMED Asthma Action Team

    Non profit Support Groups like Lung Association

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    Background

    Asthma is a significant and growing health

    burden in the United States and around the

    world High mortality and healthcare utilization

    rates in the US clearly indicate that there are

    a significant number of persons with poorly

    controlled asthma

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    US Burden of Asthma

    Current asthma prevalence: 22 millionAmericans (6.5 million children)

    Annual burden of illness:

    497,000 hospitalizations annually

    1.8 million ED visits annually

    Approximately 3600 deaths per year in 2006

    14 million lost school days in children and14.5 million lost workdays

    $16.1 billion in health costs annually

    American Lung Association Epidemiology & Statistics Unit Research Program Services. Trends inAsthma Morbidity and Mortality. July 2006. Available at: www.lungusa.org. Accessed June 25, 2007.

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    Dr. Wojtczaks Office

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    Goals of Asthma Therapy

    Minimal or no chronic symptoms day or night

    Minimal or no exacerbations

    No limitations on activities; no missed school/work Maintain (near) normal pulmonary function

    Minimal use of inhaled short-acting beta2-agonists

    Minimal or no adverse effects from medications

    Prevent progressive lost of lung function; prevent

    reduced lung growth

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    Foundation for Good Asthma

    Outcomes

    Cooperation: team-work and mutual respect

    Treating the patient as partner Assuming and accepting responsibility

    Shift of focus

    Target: Improving Outcomes Ability and desire to follow-up

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    Barriers to Quality Asthma Care

    Health Care System Lack of health insurance, primary care, coordination of

    care

    High cost of medications and services Health care providers

    Lack of recognition, severity and control

    Suboptimal compliance with guidelines

    Family Confusion about symptoms and therapies

    Adherence

    Reactive rather than proactive

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    DOD-VA Asthma Severity Table

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    DOD-VA Asthma Control Table

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    The Spirometry Gap

    The majority of asthma patients receivingcare at Navy MTFs have limited access to

    timely spirometry Results in poor compliance with national

    evidence-based asthma guidelines

    7% of Navy asthma patients identified by populationhealth navigator have documented spirometry overthe last 2 years

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    The Spirometry Gap

    The Navy wide shortage of spirometry

    resources likely results in delayed or

    misdiagnosis of asthma, limited abilityfor the provider to assess asthma

    control, and increased patient morbidity

    A recent Navy wide survey revealed only31% of providers had on site access to

    spirometry

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    Background

    The DOD-VA and NHLBI evidence based asthmaclinical practice guidelines recommend thatspirometry measurements(FEV1,FVC, FEV1/FVC)

    before and after the patient inhales a short-actingbronchodilator should be undertaken for patients inwhom the diagnosis of asthma is being considered,including children 5 years of age (NHLBI 2007).

    Patients perception of airflow obstruction is highlyvariable, and spirometry sometimes revealsobstruction much more severe than would have beenestimated from the history and physical examination.

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    Another Problem Caused by Deforestation

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    Spirometry Background

    Objective assessments of pulmonary function arenecessary for the diagnosis of asthma because,medical history and physical examination are notreliable means of excluding other diagnoses or ofcharacterizing the status of lung impairment

    Spirometry often do not correlate directly withsymptoms

    One study reports that one-third of the childrenwho had moderate-to-severe asthma werereclassified to a more severe asthma categorywhen pulmonary function reports of FEV1 wereconsidered in addition to symptom frequency

    Stout et al. 2006

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    Background

    Recent changes to assessing asthma severityand control require the primary careprovider to be able to easily measure an

    asthma patients FEV1, FEV1/FVC, andchanges post bronchodilation

    Inability to measure an asthma patientsspirometry, can result in either overestimation of asthma control, and /or underestimation of asthma severity.

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    Flow Volume Loop

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    IndicationsDiagnostic

    Evaluate symptoms, signs, abnormal lab tests Symptoms: cough, wheeze, dyspnea, chest pain

    Signs: overinflation, cyanosis, wheezing, chest deformity,crackles

    Lab tests: hypoxemia, hypercapnia, CXR, polycythemia

    Measure the effect of disease on pulmonary function

    Assess preoperative risk

    Assess prognosis Screen patients at risk for lung disease

    Smokers

    Occupational exposures

    Routine physical examination

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    Office Based Spirometry

    Focus on test that can beperformed in office setting

    Children > 5 years old

    Reliable results dependon: Experienced tech

    Devote time / effort toeach child

    Appropriate environment

    Measure Lung volumes

    Flows and timed volumes

    Reactivity

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    Dynamic Lung Volumes

    Valuable in spirometry for following theprogress of a patient with chronic lungdisease

    Can be used to assess response to treatment Help assess preoperative risk

    Do not provide the diagnosis, but can

    demonstrate if lung function is consistent witha diagnosis (ie, obstructive vs. restrictivedisease)

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    Dynamic Lung Volumes

    Forced Vital Capacity (FVC): Volume expired

    by a forced maximal expiration after maximal

    inhalation, also known as FEV6.

    Forced Exp. Volume in 1 second (FEV1):

    Volume of air forcefully expired in the first 1

    second from a position of maximal inspiration.

    Forced Exp. Flow from 25-75% of Exhalation,

    (FEF25-75): Average flow rate during the

    middle 50% of the FVC maneuver.

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    I Hope I Pass My Spirometry Test!!!

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    Administering Spirometry in Children

    Requires pt cooperation

    (unlikely in children

    less than 5-6 yrs).

    Requires a technicianwho is sensitive to the

    needs of children.

    Practice makes perfect! Calm, success-oriented

    environment.

    http://record.wustl.edu/2002/05-10-02/asthma.html
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    Administering Spirometry in Children

    Ask child to take a full breath (to maximal

    inflation), followed by a brief hold.

    Next, perform a maximal forced exhalation

    for at least 3 seconds.

    Blow out all your birthday candles.

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    Coaching During Testing

    Perhaps the MOST importantaspect of testing.

    Deep breath in, BLAST it out,keep blowing, blowing,

    blowing, DEEP breath in, andthat's done!

    Techs should become

    competent by taking theBUMED spirometry trainingcourse, TAD training, civilianPFT labs, or manufacturer

    inservice.

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    Standards for TestingEnvironment

    Torso and head erecteither sitting or standing

    Nose clips

    Pretest instructionperiod: Explain the test ( forceful

    & long expiration)

    Give demonstration

    Chance to practice

    Set a goal

    Coach / Cheerleader

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    Are We Going Too Fast?

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    Standards for TestingReporting

    Hard copy of results

    All reports include DOB

    DOT Height

    Weight

    Sex

    Race Absolute values of all

    measurements

    Percent of predictedvalues ( Predicted Source)

    Conditions of test

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    Standards for TestingGuidelines for Interpretation

    Older children and adolescents take the best

    of 3 tests

    Younger children may require more than 3

    tests

    The best test is the one with the greatest

    sum of FEV1 and FVC

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    Standards for TestingGuidelines for Interpretation

    Comment on the quality

    Use FVC, FEV1, and FEV1 / FVC % as primary guide

    for interpretation

    Interpret borderline values with caution

    Primary indicator of obstruction is FEV1/ FVC % Classify degree of obstruction with % predicted FEV1

    Determine response to bronchodilator Restriction can be suspected by spirometry but only

    confirmed with TLC measurement

    Data from Taussig LM, Chernick V, Wood R, et al: Standardization of lung function

    testing in children. J Pediatr 97: 668-676, 1980

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    Advantages of FEV1 Measurement

    Most reproducible

    Comparable between labs

    Reflects changes in lung elastic recoil

    Defines the bronchodilator response

    Best measure of prognosis

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    Spirometry Patterns

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    Role of Spirometry In Asthma

    Spirometric measures, before and after theadministration of a short acting B2-agonist

    should be obtained on all capable ( usually> 5 years-old) patients in whom a diagnosisof asthma is under consideration

    When physical exam findings are not

    present, mild asthma may be detected byperforming spirometry, especially with pre-and post bronhodilator evaluation

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    PFT Sheet

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    Role of Spirometry In Asthma

    Airflow obstruction can generally be determined by

    using the forced expiratory volume in the first second

    ( FEV1) and the forced vital capacity ( FVC), and the

    FEV1/FVC ratio

    Peak flow should not be used to diagnose asthma

    because it is less reliable due to poor reproducibility

    and dependence on patient effort Remember there is no single test sufficient or

    adequate to diagnose asthma

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    Defining Airway Obstruction

    Airway obstruction is defined as a FEV1/FVC of< .70 in adults and < .80 in children

    Obstructive defects are characterized by a

    disproportionate reduction in FEV1 with respect toFVC

    An FEV1 < 80% of normal predicted is also suggestiveof airflow obstruction

    Airways obstruction may also result in reduction ofother measures of airflow, such as mean mid-forcedexpiratory flow ( FEF 25-75)

    An FEF25-75 which is < 50-60% of predicted normalvalue is indicative of small airways obstruction

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    Reversible Airway Obstruction

    Reversible airway obstruction is documented withimprovement in FEV1 of > 12% ( usually >200 ml inadults) or clinical improvement in symptoms

    Airway obstruction is considered reversible whenFEV1 has increased > 12% after administration of a B2agonist

    Failure to demonstrate a change after bronchodilatordoes not exclude a reversible component of obstruction

    because airway inflammation may be present and notresponsive to B2 agonist

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    Role of Spirometry for Monitoring

    Asthma

    Every patient capable of spirometry should

    have testing performed at least every 1-2 years

    All MTFs where asthma care is provided

    should have access to timely spirometry

    Spirometry also indicated in the following

    situations:

    After a change in control therapy to document

    response

    When symptom history suggests poor control

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    Success

    i i i

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    Spirometry in Primary Care

    Should play a central

    role any time a

    physician prescribes

    potent bronchoactiveand anti-inflammatory

    drugs

    An objective measure

    of airway obstruction,restriction

    Petty, T.L. Benefits of and Barriers to the Widespread Use of Spirometry.

    Current Opinions in Pulm Medicine, 2005, 11:115-120.

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    Spirometry in Primary Care

    Quality of studies in PC setting: 85 of 109(78%) tests administered met all criteria foracceptability and reproducibility (reviewedby peds pulm)

    Good agreement between pediatriciansoffice testing and lab testing

    Interpretation: Pediatrician was incorrect in

    23 of 109 test (21%)

    Zanconato, S. Office Spirometry in Primary Care Pediatrics: A Pilot Study.

    Pediatrics, December 2005, 116; 792-797.

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    Spirometry Take Home Points

    Spirometric measurements are asfundamental to optimal asthma outcomes,as are measurements of pulse, blood

    pressure, temperature, height, and weight togeneral wellness checks

    Accurate spirometry requires propertraining for physicians, nurses, techs.

    Portable spirometry equipment producesquality studies and allows for reliabletesting in the primary care setting.

    R i t C t l

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    Racing to Control

    Asthma

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    Ground Zerofor the Swine Flu!!!

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    Spirometry:

    Case Based Discussion

    P l F ti T t

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    Pulmonary Function Test

    Interpretation

    Assess quality and reproducibility

    Pattern Recognition

    Obstructive ventilatory defect Asthma, CF, COPD

    Restrictive ventilatory defect Interstitial lung disease, chest wall deformities, neuromuscular

    disease

    Special cases - UAO

    Bronchodilator response

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    Reproducible Test

    Am J Respir Crit Care Med. Vol 152:1107-1136, 1995

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    Non-Reproducible Test

    Am J Respir Crit Care Med. Vol 152:1107-1136, 1995.

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    Robert Hyatt, et al. Interpretation of Pulmonary Function Tests:

    A Practical Guide, 3rd Edition. 2009.

    P tt f M j Ai

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    Patterns of Major Airway

    Obstruction

    Robert Hyatt, et al. Interpretation of Pulmonary Function Tests:

    A Practical Guide, 3rd

    Edition. 2009.

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    Measure My Lung

    Function!!!!!

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    Case 1

    A 7-year old male presents to your clinic inNovember complaining of nightly cough for thepast 2 months

    He denies symptoms of GE Reflux. He has visited the emergency room twice in the

    past year where he received albuterol with goodsymptomatic relief

    You obtain pre/post bronchodilator spirometry inyour office

    Case # 1 Spirometry

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    Case # 1 Spirometry

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    Case # 1 Numbers

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    Hang in There Almost

    Finished!!!!!!

    Case #2 Randy

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    Case #2Randy History

    6-year-old male with a history of asthma sinceinfancy

    States that he never coughs or wheeze duringthe day, and maybe 1 night/month especially atnight

    Currently on an ICS, Flovent 44 ug 2p BIDwith MPAC

    Does not perceive his asthma as limiting hisactivity, but has difficulty keeping up with hisfriends due to wheezing

    Parents believe that his asthma is wellcontrolled

    Physical exam

    Normal vital signs Chest: No wheezes but mildly prolonged

    expiratory phase

    Heart: Normal

    Spirometry FEV1: 60% of predicted

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    Racing to Control

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    Racing to Control

    Asthma

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    The End!!!!!!

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    Questions and

    Comments !!!!