Detection of Interictal Spikes

Amplitude thresholding:• Simple• Based on StD

Look for something that stands out

threshold

Easily separable: much higher

amplitude

Wider than a spike – lower slope

Lower amplitudebelow 0.6

Movement Artifacts

Background activityTrue Spikes

Spike Sequences

Not every spike gets detected

•amplitude

0.06–0.2•sharp•smoothedges

High-frequency

noise on the edges

Using derivative to separate spike from background activity

Spike: peak at the derivative Background: no peak

Derivative as a detection method

(+) Very sensitive (-) Own problems