PANTOSPEY

បរ�ិយប័ណ� ឱសថ

ប៉ង់តូស�យី ៍�ក់�មសរៃស�ម

Pantoprazole 40mg

v រេប�បេ�ប�

-ឱសថេនះ�ចេ�ប�ក�់មសរៃស�ម�� ល់េ��យេពល�យ�មយួេសរូម៉ៃ�ប 10ml (sodium chloride 0.9%) ឬ �យ� ម យួេសរូម៉ៃ�ប

100mL (sodium chloride 0.9%) ឬ�យ�មយួសូលុយស�ងគ�យកូសសំ�ប�់ក ់55mg/ml (5%) �ក�់មសរៃស�ម។ុ ុ

-េ��យេពល�យរចួេហយ សូលុយស�ង�� េំនះ�ចរក�ទុកេ�ប�នរយៈេពល១២េ�៉ង។ ុ

-�ត�វ�កសូ់លុយស�ង�� យំតៗ�មសរៃស�មក�ងរយៈេពលព២េ�១៥�ទ។ឺ ី ីុ ុ

Ø មុននងេ�បឱសថេនះ �ត�វពេ��ះ�មយួ�គ�េពទ� ឬឱសថ�រ។ឹ ិ ី

X េលខប���ិ : CAM N0277IP-17

XI ផលតិេ�យ : Nitin Lifesciences Ltd. (India)

�នបកែ�បនង�ត�តពនត�េ�យ�យក�� នឱសថ ចំណ��រ បរ�� រេពទ� នងេ�គ�ងសំ�ង។ិ ិ ិ ី ិ ិ

េលខ:១៧៤៣/១៧ឱអបស ចុះៃថ�ទ ០៥ ែខ មថុ� �� ២ំ០១៧ី ិ

I របូ�ពឱសថ :

-�ឱសថ�បេភទេម��យ�មយួទករ�ំយសំ�ប�់ក�់មសរៃសឹ

-១�បអប�់ន ១ដបេម�

II ស�ស�តុផ� ំ: ក�ង ១ដបេម��ន៖ុ

-Pantoprazole ……………………40mg

III គុណ�ពព��ល :

ំឱសថេនះស�តក�ង�ក�ម Proton Pump Inhibitors េ�បសំ�បព់��លជង�កពះដូច�៖ឺិ ុ

ំ -ជងរ�កបំពង�់�រប�� លព��ល�ត�សុតព�កពះឺ ី ិ ី ី

-េ�គស�� េកនេឡងកំរត�ត�សុតខ�ស់ក�ង�កពះ (Zollinger-Ellison) ិ ិ ី ុ

ំ -រ�ក ឬដេ��កពះ

IV �រ�មេ�ប :

-អ�ក�យ�ន�បតកម��មយួនង Pantoprazole ឬ�មយួ�រ�តុផ��ំមយួៃនឱសថេនះិ ឹ

-ចំេ�ះកូនេក�ង�យុេ��ម១៨�� ំ

V �រ�ប�ង�បយត័� :

ឱសថេនះ�ត�វ�ន�រ�ប�ង�បយត័�ចំេ�ះលក�ខណ� ដូច�ងេ��ម៖

ំ -ចំេ�ះអ�កជងេខ�យមុខ�រេថ�មធ�នធ់�រឺ

ំ -ចំេ�ះអ�កជងេខ�យមុខ�រតំរងេ�មឺ

ំ -ចំេ�ះអ�កជងថយចុះកំរត�ត�៉េញ៉ស�មក�ង�មធ�នធ់�រឺ ិ ិ ូ ុ

ំ -ចំេ�ះអ�កជងែដលកំពុងេ�បឱសថេផ�ងេទ�តដូច� digoxin ឺ

ំ -ចំេ�ះអ�កេបកបរឬប�� េ�គ�ង�៉សុនមន�ត�វេ�បឱសថេនះេទេ��ះ��ចេធ�ឲ�េធងេ�ងនង�ស�ងែភ�ក ី ិ ិ

ំ -�រេ�បឱសថេនះ�ចេធ�ឲ��ន�រេកនេឡងតចតួចៃន�នភយ័ជងឆ�ងក�ង�កពះេ�ះេវ�នឺ ិ ិ ុ

-ចំេ�ះ�ស��នៃផ�េ�ះមន�ត�វ�នែណ�ឲំ�េ�បឱសថេនះេទី ិ

-�ត�វគតព�នភយ័នងផលចំេណញេពលេ�បឱសថេនះចំេ�ះ�ស�បំេ�េ�ះកូនិ ី ិ ិ ី

-មន�ត�វេ�បឱសថេនះេលសកំរតែណ�ំិ ិ

-មន�ត�វេ�បឱសថេនះហួស�លបរេច�ទេ�ប��ស់។ិ ិ

VI ផលរ�ំន :

-វបត��បពន័�ទករៃងនង��ប�់ម៖ េកនេឡងចំនួន ��ប �់មស ថយចុះចំនួន�� ែកតិ ិ ឹ ិ

-វបត��បពន័��ំុសរ�ង�៖ �បតកម���ហ��កទ់កិ ិ ី ិ ី ិ

-វបត���រូបត�ម�នងេម�៉បូលស៖ េកនេឡងកំរត�ត�� ញ់ក�ង�ម ទម�នខ់�នែ�ប�ប�ល ថយចុះកំរត�តសូដ�ម ក�ង�ម ថយចុះ�ត�៉េញ៉ស�មក�ង�មិ ិ ិ ី ិ ិ ិ ិ ិុ ួ ូ ុ ូ ុ

-វបត��បពន័�សរៃស�ប�ទ៖ ឈក�ល េធងេ�ងិ ិ ឺ

-វបត��កពះេ�ះេវ�ន៖ �ក ចេ�� រ ក�ត ឈេ�ះ តងែណនក�ងេ�ះ េហមេ�ះ ទល់�មក ស�ត�ត់ិ ិ ឺ ឹ ួ ុ ួ

-វបត�ែស�កនង�ល�េ��មែស�ក៖ េឡងកន�លរ�ស់ ក�� ល�ត�កិ ិ ិ ិ ួ

-វបត�តំរងេ�មនងផ�វបង�រេ�ម៖ រ�កតំរងេ�មិ ិ ិ ូ ូ

VII កម�ឱសថ : គួរេជ�ស�ងេ�បរមួផ��ំមយួឱសថដូច�ងេ��មេនះ៖

-Ketoconazole, Erlotinib

-HIV medicines (Atazanavir)

-Coumarin anticoagulants

-Carbamazepine, Diazepam, Glibenclamide, Digoxin, Nifedipine

-Oral contraceptives

VIII �ររក�ទុក :

o -�ត�វទុកេ�សតុណ� �ពេ��ម ៣០ C ី

-�ត�វទុកកំុឲ��ត�វកំេ�ៃថ � នងសំេណមិ

-�ត�វទុកឲ�ផុតពៃដកូនេក�ង។ី

IX កំរតិ និងរេប�បេ�ប :

v កំរតិេ�ប៖

ំ ឱសថេនះ�ត�វ�នែណ�ឲំ�េ�ប�ក�់មសរៃស�ម�បសនេបអ�កជងមន�ចេ�បេលប�ម�ត�់ន។ឺ ិ ិ

ំ រយៈេពលព��លេ�យេ�បឱសថេនះ�ក�់មសរៃស�មគរហូតដល់៧ៃថ�។ �បសនេបអ�កជង�ចេលប�ត់ឺ ឺ ិ

វញ�ន �ត�វ �� ក េ�ប�ក�់មសរៃស�ម េហយ�ត�វប�រមកេ�បឱសថេនះ�បេភទ��បកំ់រត40mg េលប�ម�តវ់ញ។ិ ិ ិូ

កំរតេ�បឱសថេនះ�នដូច�ងេ��ម៖ិ

ំ ំ ំ ំ -សំ�បព់��លជងរ�ក�កពះនងដេ��កពះ៖ កំរត េ�បគ 40mg ក�ង១ៃថ� �ក�់មសរៃស�ម រហូត�ល់ែតអ�កជង �ច េលប �� ��បវ់ញ�ន។ឺ ឺ ិិ ិ ឺ ុ

ំ -សំ�បព់��លជងរ�កបំពង�់�រប�� លព��ល�ត�សុតព�កពះ៖ កំរតេ�បគ 40mg ក�ង១ៃថ � �ក�់មសរៃស �ម ឺ ី ិ ី ី ិ ឺ ុ

ំ ំ រហូត�ល់ែតអ�កជង �ច េលប �� ��បវ់ញ�ន។ឺ ិ

ំ - សំ�បព់��លេ�គស�� កំរត�ត�សុតខ�ស់ក�ង�កពះ (Zollinger-Ellison -Syndrome) ៖ កំរតេ�បដបូងគ 80mg ប�� បម់ក 160mg ែចក�២ដង ក�ង១ៃថ� ិ ិ ី ិ ឺុ ុ

ំ ំ �ក�់មសរៃស �ម រហូត�ល់ែតអ�កជង �ច េលប �� ��បវ់ញ�ន។ឺ ិ

-ចំេ�ះកូនេក�ង៖ មន�នកំរតែណ�ឲំ�េ�បេទិ ិ

ំ -ចំេ�ះអ�កជងេខ�យេថ�ម៖ កំរតែណ�ឲំ�េ�បគ 20mg ក�ង១ៃថ�។ឺ ិ ឺ ុ

ំ -ចំេ�ះអ�កជងេខ�យតំរងេ�ម៖ មន�ន�រែកត�ម�វកំរតេ�បេទ។ឺ ិ ិ

-ចំេ�ះមនុស��ស់៖ មន�ន�រែកត�ម�វកំរតេ�បេទ។ិ ិ