solution resides in the details · 2020-04-23 · the pannoramic digital slide scanners have won 5...

DIGITAL IHC

Solution resides in the details

IHC.indd 1 2014.05.07. 21:16:06

Standardized Digital IHC from 3DHISTECH

You need:

Standardized solutionsFor immunohistochemistry, constant quality is essential in all workflow phases. Whether it is

tissue microarray block building, slide staining and scanning or digital image analysis, you can be sure

3DHISTECH products provide the best quality.

High quality brightfield IHC staining and scanningThe Pannoramic digital slide scanners have won 5 of the 9 categories at the 2012 International Scanner

Contest, including image quality and scanning speed. The brand new SCS (Staining-Coverslipping-

Scanning) uses this award-winning scanning technology and combines an IHC stainer and coverslip-

per with it, all in one machine. The closed system approach means the need for human intervention is

minimized.

Dedicated image quantification tools3DHISTECH’s automated IHC quantification software tools are robust, powerful and adapt to different

stain intensity. Advanced pattern recognition is used for tissue separation (epithel, connective tissue),

membrane and nuclei detection algorithms provide per cell analysis. The software can be calibrated to

your lab’s applied IHC staining protocol.

Workflow, consultation, and reporting toolsMore stains mean more data and you need to channel this huge amount of information into easily

managable projects. The immunohistochemistry and TMA workflow tools from 3DHISTECH offer

a flexible and standardized way to deal with these challenges. You can work on remote slides just

like on local cases. The quantification software tool scan show your analysis results in multiple ways:

histograms, scatterplots, galleries, XLS export, and various report types.

Color deconvolution

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3DHISTECH USA INC.545 Island Rd., Suite 2D,Ramsey, NJ 07446, USA

Phone: +1-212-518-3344

TD.

Info: [email protected] www.3dhistech.com

Tissue preparation

Tissue microarray hardware


Phone: +1-212-518-3344

TD.


Staining & Imaging

SCS

• 250 slide capacity• Brightfield and 9-channel fluorescent scanning• Flash scanning technology• Motorized objective changer• Motorized camera changer

• Save reagents and time, and achieve standard quality with tissue microarrays

• Up to 550 cores in one block

• 4 core sizes from 0.6 to 2 mm

• Donor block imaging, and digital slide use for precise sampling

• Barcode reading

• NEW! Extraction of sample cores for molecular analysis

TMA Master• 5 block capacity• Small footprint

TMA Grand Master• 72 block capacity• Simultaneous loading, imaging, punching and drilling

Pannoramic250 FLASH

Pannoramic SCAN

• 150 slide capacity• Brightfield and 9-channel fluorescent scanning• Manual camera changer

Pannoramic MIDI

• 12 slide capacity• Brightfield and 9-channel fluorescent scanning• Wet slide compatible• Manual camera changer

Pannoramic DESK• 1 slide capacity• Brightfield scanning• Small footprint• Silent operation

The Pannoramic digital slide scanner systems have won the 2012 International Scanner Contest in the following categories:

• Scanning speed 20x• Scanning speed 40x• Image quality 40x• Image Analysis• Green IT

Pannoramic digital slide scanners

• Automatic white balancing and background elimination• Up to 1 slide per minute scanning speed• Award-winning quality

• IHC stainer, coverslipper, BF & FL scanner in one Standardize and save money, time and lab space!• 72 slides• Up to 40 reagents• Patented technique to detect the unstained sample and to stain only the sample area: save 50% on reagent costs!

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Production and development by


Phone: +1-212-518-3344

TD.


Diagnosis

Image quantification applicationsBreast cancer diagnostic tools: dedicated image analysis algorithms for several predictive markers

(ER, PgR, HER2, etc.)

PatternQuant

• Trainable algorithm for tissue segmenta- tion

• Epithel and connective tissue separation for cell based analysis

NuclearQuant

• Predefined profiles for ER, PgR

• Can be adapted to your lab protocols

• Multiple scoring options: positivity index, H-score, Allred, etc.

MembraneQuant

• Predefined profile for HER2

• Positive and negative cell detection

• Can be adapted to your lab protocols

• Multiple scoring options: H-score, field score

DensitoQuant

• Simple, fast yet effective classifica- tion of IHC stained samples

• Area and average intensity measure- ments of classes

Workflow toolsTumorBoard

• For comparing of differently stained samples of the same case

• Manual scoring possibility

• Flexible gallery to support tumor board reviews

• Uses measurement data from the image analysis applications

TMA

• For high throughput tissue microarray analysis

• Project based: multi-user, multi-slide

• Powerful TMA spot gallery

• Uses measurement data from the image quantification applications


Phone: +1-212-518-3344

TD.


Reviewing and reporting

Measurement Gallery

• Reviewing possibility

• Cell relocalization on the sample

• Single-click rescoring

CaseReport

• Standardized presentation

of the pathology report

• Patient and measurement

data on one sheet

• Reference image from the

diagnostic area

• Printable format

NEW

IHC.indd 4 2014.05.07. 21:16:16

solution resides in the details · 2020-04-23 · the pannoramic digital slide scanners have won 5...

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