Skeletal Skeletal PathologyPathology

Skeletal system Skeletal system has 206 boneshas 206 bones

Anatomy of BoneAnatomy of Bone

Osteoporosis-Osteoporosis-disease characterized by low bone mass &

structural deterioration of bone tissue

normal bone osteoporotic bone

Skeletal Skeletal pathologpatholog

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Osteochondroma Osteochondroma

http://www.rad.washington.edu/mskbook/dysplasia.html

OsteochondroOsteochondroma ma

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

Osteosarcoma of Osteosarcoma of FemurFemur

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

metastatic metastatic cancer cancer

(radius)(radius)

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

Giant Cell Giant Cell TumorTumor

Pelvis--left Pelvis--left ischial ischial ramusramus

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

Giant Cell Tumor--proximal Giant Cell Tumor--proximal femurfemurhttp://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

Bone metastases of spine & pelvis Bone metastases of spine & pelvis

dark spots indicate osteolytic lesions (destroy dark spots indicate osteolytic lesions (destroy bone)bone)

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MRI scan of MRI scan of spine spine

demonstrates demonstrates metastatic metastatic

lesion lesion destroying C7destroying C7

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

http://www.rad.washington.edu/mskbook/dysplasia.html

OsteopetrosOsteopetrosisis

Failure of Failure of osteoclastosisosteoclastosis

Note Note unusuunusual al bone bone densitdensityy

Paget’s DiseasePaget’s Disease

http://www.amershamhealth.com/medcyclopaedia/Volume%20III%201/Pagets%20disease.asp

Note hazy Note hazy appearance appearance of craniumof cranium

Radiograph-Radiograph--Scoliosis-Scoliosis

(lateral (lateral curvature of curvature of

spine)spine)

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

Mild scoliosis Mild scoliosis in lumbar in lumbar

regionregion

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

compression compression fractures due fractures due

to to osteoporosis osteoporosis

that results in that results in kyphosiskyphosis

MRI of SpineMRI of Spine

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

Compression Fx.

Collapse of vertebra

What’s left of vertebral What’s left of vertebral bodybody

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

Herniated disk Herniated disk compressing spinal compressing spinal

cord.cord.

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

Osteoarthritis Osteoarthritis of vertebral of vertebral

columncolumn

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

Normal femoral Normal femoral head removed head removed after fracture.after fracture.

Note smooth Note smooth articular articular cartilage.cartilage.

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

Arthritic femoral Arthritic femoral head removed head removed due to disease.due to disease.

Note rough Note rough articular surface.articular surface.

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

Osteoarthritis Osteoarthritis (proximal (proximal

femur)femur)

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

Osteoarthritis Osteoarthritis anterior/anterior/superisuperi

or patella & or patella & posterior tibiaposterior tibia

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

Bunions Bunions

Rheumatoid Rheumatoid ArthritisArthritis

http://www-medlib.med.utah.edu/WebPath/BONEHTML/BONEIDX.html

Rheumatoid nodules at pressure Rheumatoid nodules at pressure points of elbowspoints of elbows

Gout from sodium urate crystals Gout from sodium urate crystals deposited in joints. deposited in joints.

Chronic gout eventually destroys Chronic gout eventually destroys bone.bone.

Early stage of gout.

More advanced stage.

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