sinergia e incompatibilidad entre filtros...

Vanessa ArrudaGerente de Marketing Técnico LatamMarzo 2012

Sinergia e Incompatibilidad entreFiltros Solares

Agenda• Sol y piel – porque necesitamos la protección UV?

• Cambios Regulatórios y Retos

• Eligiendo filtros UV y sinérgia entre ellos

• Fotoestabilidad y desempeño de PARSOL® 1789

• Tendencias de Mercado Europa

Agenda





•Sol y piel – porque necesitamos la protección UV?

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UVC UVB UVA

ULTRAVIOLETA VISÍVEL INFRAVERMELHO

100 280 320 400 800 1700

Efeitos

Bioquímicos

Efeitos

Bioquímicos*

Efeitos

Luminosos

UVA-1 (longo): 340-400

UVA-2 (curto): 320-340

*Arch Dermatol Res 1982;272:229-38; Photodermatol Photoimmunol Photomed 1992/1993;9:275-8

UVC UVB UVA

ULTRAVIOLETA VISÍVEL INFRAVERMELHO

100 280 320 400 800 1700

Efeitos

Bioquímicos

Efeitos

Bioquímicos*

Efeitos

Luminosos

UVA-1 (longo): 340-400

UVA-2 (curto): 320-340

*Arch Dermatol Res 1982;272:229-38; Photodermatol Photoimmunol Photomed 1992/1993;9:275-8

Radiación UVB y UVA

Rayos UV son losresponsables por unos

90% delfotoenvejecimiento

prematuro!

Radiación UVB y UVA: daños en la piel• Rayos UVB

• Alta energía pero no penetra en la piel muyprofundo – principalmente afecta laepidermis

• Primera causa de quemaduras solares• Causa daños en el DNA y contribuye al

cancer de piel en un 65%• Actua como inmunosupresor• Contribuye al fotoenvejecimiento

• Rayos UVA• Penetra mais profundamente en la dermis,

dañando el colágeno y afectando laproducción de elastina que lleva a lasarrugas

• El daño en la piel es cumulativo y la mayorcausa de fotoenvejecimiento

• Estimula la producción de melanina ypuede causar la pigmentación

• Causa danõ en el DNA y contribuye alcancer de piel en un 35%

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Radiación UVB y UVA: daños en la piel

Cual es la edad de la piel?

Factores intrínsicos de la edadvs.Factores externos(ej. fotoenvejecimiento)

• Las estaciones – más alta en verano y menor en invierno.• Hora del día – más alta al medio día• Latitud – más alta en Ecuador• Altitud – alta radiación UVB

La radiación UVB depende de vários factores

Radiación UVA es mas constante durante el año y horas del día

102030405060708090

100

*Sources: The Skin Cancer Foundation, Mayoclinic.com, AAD.org

Y porque la protección UVA?

• Prevención del cancer de piel: UVAcontribuye en un 35% de todos los canceresde piel

• Prevención de daños en la piel, daños alDNA, mutaciones p53

• Prevención de la actividad inmunosupresora

• Prevención de manchas de edad y otraspigmentaciones

• Prevención del fotoenvejecimiento yarrugas

• Prevención del 90% de todos los sintomasdel envejecimiento prematuro!






•Cambios Regulatórios y Retos

CategoryLabeled SunProtection

Factor

Measured SunProtection

Factor

Recommendedminimum UVA

ProtectionFactor

Recommendedminimumcritical

wavelength

Very High Protection 50+ > 601/3 of labeled SPF

370nm

High Protection50 50 - 59.9

30 30 - 49.9

Medium Protection

25 25 - 29.9

20 20 - 24.9

15 15 - 19.9

Low Protection10 10 - 14.9

6 6 - 9.9

Threshold: go / no go criteria

Recomendación Europea 2006

UVA






Eligiendo filtros UV y sinérgia entre ellos

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Alto desempeño en SPFUV A contribution to SPF

0,000

0,001

0,010

0,100

1,000

10,000

290 300 310 320 330 340 350 360 370 380 390 400

rela

tive

Ene

rgy

nm

Erythema Action Spectrum

0

0,2

0,4

0,6

0,8

1

1,2

290 300 310 320 330 340 350 360 370 380 390 400

W/q

m*n

m

nm

UV-SSR Source Spectrum


0,00

0,01

0,01

0,02

0,02

0,03

0,03

0,04

0

0,2

0,4

0,6

0,8

1

1,2

290 300 310 320 330 340 350 360 370 380 390 400

W/q

m*n

m

nm

UV-SSR Source Spectrum


Effective Erythemal Radiation during SPF test

90 %95 % 98 %Erythemal

Energy

14

l, nm

E 1/1

Como elegir el filtro UVA?Comparación del desempeño de filtros UVA

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Absorptance - 2.9 % -3.5 % -2.9 % -1.9 %

UVA Contribution - Experimental Data

Una buena protección UVA entrega 2 – 4 % Absorbancia:también colabora para un alto SPF!

Avobenzone concentration

SPF

in v

ivo

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Alto desempeño en SPF

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Productos de mercado con nivelesde estabilización 100% contienen:

• Octocrileno

y/o

• Uso de estabilizantesadicionales, comoMethilbenzelideno canfora(MBC)

70%

75%

80%

85%

90%

95%

100%

3.0% 4.0% 5.0% 6.0% 7.0% 8.0% 9.0%

Octocrylene use level

% HPLC Recovery Avobenzoneafter Radiation

La estabilización de la Avobenzona esnecesaria

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Alto desempeño en SPF

Dose-Response for a O/W system

Overview de los Filtros Solares DSMButhyl Methoxydibenzoylmethane (BMDBM) UVA filter

Ethylhexyl Methoxycinnamate (OMC) UVB filter

Octocrylene UVB filter

4-Methylbenzylidene Camphor approved UVB filter outside US

Ethylhexyl Salicylate UVB filter

Homosalate UVB filter

Phenylbenzimidazole Sulfonic Acid UVB filter (water soluble)

Titanium Dioxide UVB filter (inorganic)

Titanium Dioxide TX50 AB UVB filter (inorganic)Polysilicone-15 approved UVB filter outside

US (polymeric) (permitted inhair care applications and as afoto stabilizer in US)

INCI name: Buthyl Methoxydibenzoylmethane (BMDBM)USAN: Avobenzone E1

1 = 1100 - 1180 (Ethanol)max: 357 nm (UVA absorber)

PARSOL 1789

• Uso de solventes para mantener el producto ensolución

• Calentar hasta 80 - 85 °C : solución clara

• Uso de agentes quelantes para evitar complejoscon metales de transición

• Seleccionar con cuidado sistema de preservación(no formaldehyde y sus donantes)

• Impurezas de hierro pueden llevar a cambio decolor

Avobenzona (PARSOL® 1789) es 100% fotoestable cuando esformulada junto con Octocrileno (PARSOL® 340) y/o 4- methylbenzilidenocanfora (PARSOL® 5000)

INCI name: OctocryleneUSAN: Octocrylene

E11 = 340 - 370 (Ethanol)max: 303 nm (UVB absorber)PARSOL 340

•PARSOL® 340 es fácil de manejar. Puede ser facilmente disuelto en la fasegrasosa de la formulación.

•PARSOL® 340 es compatible con la gran mayoría de los ingredientescosméticos

•PARSOL® 340 es un excelente fotoestabilizador de la Avobenzona

•PARSOL® 340 es un óptimo solvente de la Avobenzone (25%)

Benefícios 3 en 1:- Filtro UVB- Estabilizante para Avobenzone- Solvente para otros filtros UV

Nuevas oportunidades para el OctocrilenoLista de filtros UV permitidos y su concentración máxima de uso

Calculado como Esther 14%:

INCI name: 4-Methylbenzylidene Camphor

E11 = 930 - 990 (Ethanol)max: 299 nm (UVB absorber)PARSOL 5000

• Se recomienda usar solventes para mantener el producto en

solución

• Calentar hasta 80 - 85 °C para obtención de una solución clara

• MBC es un excelente estabilizante para Avobenzone

INCI name: Ethylhexyl Methoxycinnamate (OMC)

PARSOL MCXE1

1 = 835 - 865 (Ethanol)max: 308 nm (UVB absorber)

• PARSOL® MCX es facil de manejar. Se mantiene liquido y nocristaliza en la formulacion.Puede ser facilmente disuelto en la fase oleosa de la formulación

• PARSOL® MCX es un excelente solvente paras otros filtros UV

INCI name: Phenylbenzimidazole Sulfonic Acid

E11 = 920 - 1000 (Water)max: 306 nm (UVB absorber)PARSOL HS

• Filtro UVB soluble en água. Necesita neutralización, con las bases: (para 1gde PARSOL® HS)– KOH 100% 0.20 g– NaOH 100% 0.15 g– TEA 100% 0.65 g– AMP 100% 0.35 g– Tromethamine 100% 0.50 g

• Usando AMP o TEA como neutralizante no disminuye la viscosidad de laemulsión

• Formular siempre en pH mayor que 7,0 para evitar cristalización

INCI name: Ethylhexyl Salicylate

PARSOL EHSE1


• EHS es facil de manejar. Se mantiene liquido y no cristaliza enla formulacion.Puede ser facilmente disuelto en la fase oleosa de laformulación

• EHS es un optimo solubilizante para PARSOL® 1789

INCI name: Homosalate

PARSOL HMSE1


• HMS es facil de manejar. Se mantiene liquido y no cristaliza enla formulacion.Puede ser facilmente disuelto en la fase oleosa de laformulación

• EHS es un optimo solubilizante para PARSOL® 1789

INCI name: Titanium Dioxide, Silica, Dimethicone• Primary particle size: 17-23*nm (mean value)

max: 316 nm (UVB absorber)

Rutile Titanium Dioxide Core,

Silica, Dimethicone,

PARSOL TX

PARSOL TX

• TX es fácil de dispersar. Puede ser añadido directamente en lafase oleosa de la formulación.

• TX es compatible con la Avobenzone y la gran mayoría delosingredientes cosméticos, especialmente espesores deacrilato

• TX50 AB es la dispersion del PARSOL TX en Alkyl Benzoate

INCI name: Polysilicone-15

E11 = 160 - 190max: 312 nm (UVB absorber)PARSOL SLX

• PARSOL® SLX es estable en pH del 4-9. puede ser añadido enla fase oleosa y calentado hasta 80°C por 6 hs sin perderactividad.

• PARSOL® SLX es compatible con filtros organicos einorganicos, emolientes y emulsificantes mas usados

• PARSOL® SLX es aprobado en EU con máxima concentraciónde uso permitida de 10% en formulaciones cosméticas

PARSOL SLXAplicaciones

Sun Care/ Skin Care

• PARSOL® SLX contribuye para la obtención de alta protecciónsolar

• Para productos Sun Care y Daily Care, para productos parapieles sensitivas

Hair Care

• Protege el color de los cabellos teñidos

• Mejora la peinabilidad del cabello después de la radiación UVcuando es comparado con el placebo

• Silicon base product: efecto condicionante, aumento delbrillo, …

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Argentina

The Natura Plant Verano range is enriched with coconut lipids andUV filter and claimed to hydrate and restore damaged hairstrands, preparing them for sun exposure while providing aprotective anti-UV layer to provide long-lasting protection.Available as part of the range are: Crema para Peinar (SummerCombing Cream), retailed in a 170ml pack; and Mascaril…

33

Natura Plant Verano Summer Combing Cream

1736314

Natura Cosmeticos

Feb 2012

Aqua, Cetearyl Alcohol, PPG-15 Stearyl Ether, Dimethicone, Dimethiconol, TEA-dodecylbenzenesulfonate, Elaeis Guineensis Oil, parfum, Polysilicone-15, BehentrimoniumChloride, Cetrimonium Chloride…

Hair Treatments

Seasonal, Damaged Hair, Botanical/Herbal, Ethical - Environmentally Friendly Package, UVProtection, Long-Lasting*, Moisturising / Hydrating

Country:

Company:

Date Published:

Sub-Category:

Ingredients:

Claims:

ARS56.0$13.14 / €9.91

Price (local):Price (majorcurrencies):

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Israel

Schwarzkopf Gliss Hair Repair Color Protection 30 Reflex-ShineTreatment repairs coloured, dyed hair from inside out. The leave-in treatment protects the colour from fading, and gives up to90% colour retention after 30 applications. The product repairsthe hair structure and smoothes the hair surface for animmediate, shimmering shine. It offers tangibly no…

34

Schwarzkopf Gliss Hair Repair Color Protection 30 Refle…

1141687

Schwarzkopf & Henkel

Jul 2009

Aqua, Alcohol Denat. (Denatured), Polyquaternium-37, Trisiloxane, Dimethicone, Mica,Amodimethicone, Polyquaternium-11, parfum (fragrance), Prunus Armeniaca Kernel Oil, Panthenol,Propylene Glycol, dicaprylate/dicaprate, Polysilicone-15, Glycerin, Laurdimonium HydroxypropylHydrolyzed Wheat Protein (Hydrolyzed), Polyquaternium-10, Linalool, Hexyl Cinnamal, Lactic Acid,PPG-1 Trideceth-6, Cetrimonium Chloride, Cyclomethicone, Hydrolyzed Keratin (Hydrolyzed),Trideceth-12, Butylphenyl Methylpropional, Benzyl Alcohol, L-limonene, Coumarin, CI 77891

Hair Treatments

Brightening / Illuminating*, Time/Speed, Damaged Hair

Country:

Company:

Date Published:

Sub-Category:

Ingredients:

Claims:

ILS39.99$10.19 / €7.34

Price (local):Price (majorcurrencies):

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Photostability tests have been done in film:Photostability tests have been done in film:

70% ethanol / 30% Finsolv TN + Myritol 31870% ethanol / 30% Finsolv TN + Myritol 318

Filtros UV

1.PARSOL® 340 Octocrylene

2. PARSOL® 5000 4-MethylbenzylideneCamphor

3.Eusolex 4360 Benzophenone-3

4.PARSOL® SLX Benzophenone-3

5.Tinosorb S Bis-EthylhexyloxyphenolMethoxyphenyl Triazine

Estabilizantes6.Tinogard Q Tris(tetramethylhydoxypiperi-

dinol) citrate7.Tinogard TL Benzotriazolyl Dodecyl

p-Cresol

8. Corapan TQ Diethylhexyl 2,6-Naphthalate

9.Hallbrite BHB Butyloctyl Salicylate

10. Polycrylene Polyester-8

11. Oxynex ST Diethylhexyl SyringylideneMalonate

Fotoestabilizantes para Avobenzona

Dissolving inDissolving in 50ml Ethanol

Glass plate 10cmGlass plate 10cm22

layerlayer 2mg/cm2 irradiationirradiation25 MED

~~ 70% evaporationevaporation

dryingdrying

analysis of solution :analysis of solution :- spectrofotometric- chromatographic

(e.g. HPLC)

light

Método de análisis de la fotoestabilidad

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Butyl MethoxydibenzoylMethane 4.0% 4.0% 4.0% 4.0% 4.0% 4.0% 4.0% 4.0% 4.0% 4.0% 4.0% 4.0%

Octocrylene 2.0%

Bis EthylhexyloxyphenolMethoxyphenyl Triazine 2.0%

4-MethylbenzylideneCamphor 2.0%

Benzophenone-3 2.0%

Benzotriazolyl Dodecyl p-Cresol 2.0%

Tris(tetramethylhydroxypiperidinol)citrate

2.0%

Polysilicone-15 2.0%

Butyloctyl Salicylate 2.0%

DiethylhexylSyringylidenemalonat 2.0%

Polyester-8 2.0%

Diethylhexyl-2,6-Naphthalate 2.0%

Content of BMDBM after25 MED 23% 77% 70% 69% 58% 53% 53% 45% 44% 43% 42% 34%

2% stabilizer

Butyl Methoxydibenzoyl Methane 4.0% 4.0% 4.0% 4.0% 4.0% 4.0% 4.0% 4.0% 4.0% 4.0% 4.0% 4.0%

Octocrylene 3.6%

4-Methylbenzylidene Camphor 4.0%

Diethylhexyl Syringylidene-malonat 4.0%

Bis EthylhexyloxyphenolMethoxyphenyl Triazine 4.0%

Benzophenone-3 5.0%

Polysilicone-15 4.0%

Benzotriazolyl Dodecyl p-Cresol 2.0%

Tris(tetramethylhydroxy-piperidinol)citrate 2.0%

Polyester-8 3.0%

Butyloctyl Salicylate 5.0%

Diethylhexyl-2,6-Naphthalate 5.0%

Content of BMDBM after 25 MED 23% 90% 87% 82% 81% 80% 53% 53% 53% 50% 50% 47%

2-5% stabilizer

Eficácia de los fotoestabilizantes

Butyl MethoxydibenzoylMethane

4,0% 4,0% 4,0% 4,0% 4,0%

Octocrylene 4,0% 4,0% 4,0% 4,0% 4,0%

Bis EthylhexyloxyphenolMethoxyphenyl Triazine

4,0%

4-MethylbenzylideneCamphor

2,0% 4,0%

Polysilicone-15 4,0%

Content* BMDBM after25MED 90% 100% 95% 100% 95%

* deviation ±5%

100% de estabilización de la Avobenzona es posible !!

Mezclas de estabilizantes

Rutile or Anatas core

Silica, or Al2O3, Stearic Acidbetween 3% and 30% coatingmaterial

Dimethicone, Simethicone

INCI of ingredient CAS No. EINECS

Titanium Dioxide 13463-67-7 236-675-5

Silica 7631-86-9 262-373-8

Dimethicone(C2H6OSi)xC4H12Si

9016-00-6 polymer exempt

Recubrimiento del TiO2

Coated TiO2

PARSOL TX

Influencia del tamaño de los cristales enpropiedades de absorción

Cual es la mejoropción?

• BMDBM and TiO2 is a common combinationin sun-care and day-care in Europe and Asia Pacific.

• Al2O3 is one of the most commonly used coatingmaterial for TiO2.

• As a result, BMDBM - Al 3+ complex is formed

• Reduced amount of BMDBM is detectedif a formulation is analyzed, leading to potentialproblems in UVA protection, but more importantis the risk of crystal formation do to the lowersolubility of this complex.

• Solubility of 1789/Al complex 2% in Finsolv TN

• Problems with customers and authorities(reduced content of used and eventually charged Parsol 1789)

Estabilidad del desempeño de Avobenzonay TiO2

400x 400x

• Formulation 3 months at 43°C,formulated with 10% Al coatedTiO2

• Same formulation, same storagetime with 10% of Parsol TX doesn’thave any crystals


%

• 4% BMDBM

• 10% TiO2 /Aluminium Hydroxide /Stearic Acid

• HPLC Method

Formation of Al - BMDBM complex

An Al - BMDBM complex appears already after 2 weeks






•Tendencias de Mercado Europa

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Consumer‘s Habits & Attitudes in Sun Care

Protección Solar &Cuidado diário

• More than sunburn prevention—it's balanced sundamage protection.

The truth is, most sunscreens don't protect againstboth UVB and UVA rays. But, now from Neutrogena,comes a complete line of Sun Protection productsfeaturing breakthrough Helioplex™ technology. Neverbefore has skin protection against the sun's rays beenso complete—or balanced.

"Helioplex™ delivers unbeatable UVAprotection. It works better to helpprevent damaging UVA rays frompenetrating deep under skin's surface.Dry-Touch technology absorbs excesssunscreen oils, leaving a clean,lightweight, non-shiny finish."

Enfasis en alto SPF, protección UVA, yConveniencia

Anti-edad, Protección UVA y UVB

New ultralight formula to hydrate the skin.WaterproofProtects DNA cells against damage caused by the

sunInnovative system of protective UVA and UVB

filters with folic acid to provide betterprotection from marks, lines and sun damage.

PIZ BUIN® IN SUN LOTIONHelioplex™ technology provides photostable UVA/UVB broadspectrumprotection while Vitamin E helps neutralise free radicals which causepremature skin ageing. A rich hydration complex helps your skinremain moisturised all day, leaving it smooth and silky soft. Sweatand water-resistant.AVAILABLE SPF's: 200ml - SPF 6, 10, 15, 20, 30, 50+

PIZ BUIN® ACTIVE FRESH COOLINGThe ACTIVE Fresh Cooling Spray cools the skincontinuous spray system is easy to applynon-greasy formula dries within secondsenriches the skin with moisture and essential vitaminsHelioplex™, a breakthrough technology newlydeveloped by PIZ BUIN®, provides photostable,efficient protection against harmful UVA/UVB raysSweat -and very water- resistant.AVAILABLE SPF's: 20, 30

Helioplex- Protección UVA/UVB avanzada

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Combinaciones de Filtros UV en productosBDF lanzados a partir de octubre 2011:

Butyl Methoxydibenzoylmethane (25),Octocrylene (17), Bis-ethylhexyloxyphenolMethoxyphenyl Triazine (14), EthylhexylMethoxycinnamate (11), Homosalate (9), SodiumPhenylbenzimidazole Sulfonate (8), EthylhexylSalicylate (7), CI 77891 (5) Titanium Dioxide,Ethylhexyl Triazone (4), Diethylhexyl ButamidoTriazone

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New Product Launches BDF since 11.2011• Nivea Sun Kids Caring Sun Spray SPF 50 + offers very high and

immediate protection for children's delicate skin. The product isvery water resistant and has a non-sticky, easily absorbed formulathat offers deep and long lasting moisture for smooth skin. It isformulated to help reduce the risk of sun allergies and has beenskin compatibility dermatologically tested and approved. Theproduct retails in a value size 300ml pack.

•aqua, glycerin, octocrylene, butylene glycol dicaprylate/dicaprate,alcohol denat., butyl methoxydibenzoylmethane, bis-ethylhexyloxyphenol methoxyphenyl triazine, homosalate,titanium dioxide, sodium phenylbenzimidazole sulfonate,ceteareth-20, methyl propanediol, C18-36 acid triglyceride,tocopheryl acetate, diethylhexyl butamido triazone, ethylhexylmethoxycinnamate, VP/hexadecene copolymer, acrylates/C10-30alkyl acrylate crosspolymer, trimethoxycaprylylsilane, trisodiumEDTA, ethylhexyl glycerin, methylparaben, ethylparaben,phenoxyethanol, BHT, limonene, linalool, benzyl benzoate,hydroxyisohexyl 3-cyclohexene carboxaldehyde, hexyl cinnamal,benzyl salicylate, butylphenyl methylpropional, alpha-isomethylionone, eugenol, citronellol, coumarin, parfum

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Nivea Sun Alpin Cream & Stick SPF 30Nivea Sun Alpin Cream & Stick SPF 30 is claimed to combine twoproducts in one: a cream and a stick; offering immediate protectionof the face and lips under extreme conditions, protecting the skinagainst the winter sun, cold, and wind. The cream is designed toprotect the face, while the stick is for the lips.

Aqua (water), butylene glycol dicaprylate/dicaprate, C12-15 alkylbenzoate, butylene glycol, glycerin, PEG-30 dipolyhydroxystearate,titanium dioxide, butyl methoxydibenzoylmethane, ethylhexyltriazone, isopropyl stearate, cera microcristallina, alcohol denat.,paraffinum liquidum, bis-ethylhexyloxyphenol methoxyphenyltriazine, panthenol, tocopheryl acetate, glycine, C18-36 acidtriglyceride, cetyl dimethicone, sodium starch octenylsuccinate,trimethoxycaprylylsilane, magnesium sulfate, trisodium EDTA,ethylhexylglycerin, phenoxyethanol, methylparaben,propylparaben, limonene, linalool, benzyl benzoate,hydroxyisohexyl 3-cyclohexene carboxaldehyde, hexyl cinnamal,benzyl salicylate, butylphenyl methylpropional, alpha-isomethylionone, eugenol, citronellol, coumarin, parfum

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Nivea Sun Baby Bloqueador Solar(Baby Sunblock SPF 60)

Nivea Sun Baby Bloqueador Solar (Baby Sunblock SPF 60) is nowavailable in a newly designed 115g pack. It features adermatologically tested, water-resistant formula, designed toprotect baby's delicate skin against UVA and UVB sun rays, helpingto prevent sunburn. Free of fragrance, alcohol and colourants,the product retails in a 115ml pack.

aqua, butylene glycol dicaprylate/dicaprate, C12-15 alkylbenzoate, titanium dioxide, butyl methoxydibenzoylmethane,alcohol, glycerin, bis-ethylhexyloxyphenol methoxyphenyltriazine, dicaprylyl carbonate, ethylhexyl triazone,phenylbenzimidazole sulfonic acid, cetearyl alcohol, cetylalcohol, glycine, C18-36 acid triglyceride, glyceryl stearate SE,hydrogenated coco-glycerides, tocopheryl acetate,VP/hexadecene copolymer, xanthan gum, PEG-40 castor oil,trisodium EDTA, sodium cetearyl sulfate, triethoxycaprylylsilane,zinc sulphate, magnesium sulphate, ethylhexyl glycerin,phenoxyethanol, methylparaben, propylparaben, sodiumhydroxide

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Combinaciones de Filtros UV en productosL'Oreal lanzados a partir de octubre 2011

Butyl Methoxydibenzoylmethane (378), Octocrylene(367), Drometrizole Trisiloxane (292), EthylhexylTriazone (239), Terephthalylidene Dicamphor SulfonicAcid (238), Ethylhexyl Salicylate (101), Bis-ethylhexyloxyphenol Methoxyphenyl Triazine (96),Ethylhexyl Methoxycinnamate (46), Titanium Dioxide(25), Phenylbenzimidazole Sulfonic Acid (13),Diethylhexyl Butamido Triazone (11), Benzophenone-3(9), 4-methylbenzylidene Camphor (8), Homosalate (3

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Vichy Laboratoires Capital Soleil Ansigt SolcremeVichy Laboratoires Capital Soleil Ansigt Solcreme (FacialSun Crème SPF 25) is suitable for normal to dry skin and isformulated without parabens. It is foto-stable and madewith Mexoryl-XL and DHC for cellular protection.

Aqua (water), octocrylene, glycerin, alcohol denat.,propylene glycol, C12-15 alkyl benzoate,cyclohexasiloxane, ethylhexyl salicylate, butylmethoxydibenzoylmethane, ethylhexyl triazone, bisethylhexyloxyphenol methoxyphenyl triazine, talc,drometrizole trisiloxane, acrylates/C10-30 alkyl acrylatecrosspolymer, aluminum hydroxide, aluminum starchoctenylsuccinate, ascorbyl glycoside, citric acid,ethylhexylglycerin, isohexadecane, methylsilanol/silicatecrosspolymer, neohesperidin dihydrochalcone, parfum(fragrance), pentasodium ethylenediamine tetramethylenephosphonate, phenoxyethanol, polysorbate 60, polysorbate80, sodium hyaluronate, sodium polyacryloyldimethyltaurate, sorbitan oleate, stearic acid, titanium dioxide,tocopherol, triethanolamine

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Ambre Solaire UV-Ski ExtremeConditions Protection FSP 50+

Ambre Solaire UV Ski Extreme Conditions Protection CreamSPF 50+ is claimed to offer a superior level of UVAprotection, and is suitable for sun intolerant skin.

Aqua (water), C12-15 alkyl benzoate, cyclohexasiloxane,cyclopentasiloxane, alcohol denat., isohexadecane,ethylhexyl salicylate, propylene glycol, titanium dioxide,bis-ethylhexyloxyphenol methoxyphenyl triazine,octocrylene, butyl methoxydibenzoylmethane, PEG-30dipolyhydroxystearate, glycerin, terephthalylidenedicamphor sulfonic acid, lauryl PEG/PPG-18/18 methicone,ethylhexyl triazone, tocopherol, dodecene,phenoxyethanol, ethylparaben, triethanolamine,poloxamer 407, dimethicone, pentasodiumethylenediamine tetramethylene phosphonate,drometrizole trisiloxane, propylparaben, isobutylparaben,sorbitol, methylparaben, butylparaben, opuntiacoccinellifera flower extract, glycine soja (soybean oil),

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Ice Effect Moisturising Sun Milk SPF 30L'Oréal Solar Expertise Icy Protection Leche SolarHidratación Efecto Hielo (Ice Effect Moisturising Sun MilkSPF 30) features a non-greasy, non-sticky, water- andsweat-resistant, moisturising formula with SPF 30 sunprotection against UVA/UVB rays and a blend of watermicro-drops with hydrating milk.

aqua (water), glycerin, alcohol denat., octocrylene,ethylhexyl salicylate, butyl methoxydibenzoylmethane,butylene glycol, ethylhexyl triazone, titanium dioxide,dimethicone, phenoxyethanol, sodium acrylatescrosspolymer, drometrizole trisiloxane, glyceryl stearate,behenyl alcohol, triethanolamine, terephthalylidenedicamphor sulfonic acid, methylparaben, caprylyl glycol,menthol, glyceryl stearate citrate, disodium ethylenedicocamide PEG-15 disulfate, ethylparaben, ammoniumpolyacryldimethyltauramide, ammoniumpolyacryloyldimethyl taurate, acrylates copolymer,disodium EDTA, aluminium hydroxide, stearic acid,tocopherol, sodium hyaluronate, linalool, silica, CI 42090(blue 1), parfum (fragrance)

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Delial Ambre Solaire Resisto Niños SPF 50Garnier Delial Ambre Solaire Resisto Niños SPF 50 LecheHidratante Muy Alta Proteción (SPF 50 Childrens HighProtection Moisturising Sun Milk) features a patented Mexoplexfilter system to protect kids sensitive skin against UVA andUVB rays. Enriched with vegetable wax, it is claimed to be twotimes more resistant to water than other suncreams.

Aqua (water), C12-15 alkyl benzoate, alcohol denat.,isohexadecane, ethylhexyl salicylate, propylene glycol,titanium dioxide, cyclohexasiloxane, butylmethoxydibenzoylmethane, PEG-30 dipolyhydroxystearate,bis-ethylhexyloxyphenol methoxyphenyl triazine, octocrylene,glycerin, cyclopentasiloxane, lauryl PEG/PPG-18/18methicone, terephthalylidene dicamphor sulfonic acid,synthetic wax, ethylhexyl triazone, tocopherol, dodecene,triethanolamine, silica, poloxamer 407, dimethicone,ammonium polyacryldimethyltauramide, ammoniumpolyacryloyldimethyl taurate, simmondsia chinensis (jojobaseed) oil, pentasodium ethylenediamine tetramethylenephosphonate, drometrizole trisiloxane, isopropyl lauroylsarcosinate, isostearyl alcohol, caprylyl glycol,disteardimonium hectorite,

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Eau Thermale Avène Sol Lotion(Sun Lotion SPF 50+)

Eau Thermale Avène Sol Lotion (Sun Lotion SPF 50+) is suitablefor babies' sensitive skin and is very water resistant with veryhigh UVA and UVB protection. The hypoallergenic and non-comedogenic product is fragrance- and paraben-free. It retailsin a 100ml pack

avene aqua, octocrylene, cyclomethicone, dicaprylyl ether,methylene bis-benzotriazolyl tetramethylbutylphenol, aqua,butyl methoxydibenzoylmethane, cetearyl isononanoate,glycerin, titanium dioxide, bis-ethylhexyloxyphenolmethoxyphenyl triazine, C12-15 alkyl benzoate, diisopropyladipate, potassium cetyl phosphate, stearyl alcohol,PVP/eicosene copolymer, caprylic/capric triglyceride, caprylylglycol, decyl glucoside, dimethicone, disodium EDTA, glycerylbehenate, glyceryl dibehenate, propylene glycol, silica, sorbicacid, tocopheryl glucoside, tribehenin, xanthan gum,tocopherol

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Eau Thermale Avène Crema para ZonasSensibles

Eau Thermale Avène Crema para Zonas Sensibles (Cream forSensitive Areas) is now available in a newly designed 15mlpack. This water resistant product features SPF 50+ providingUVA and UVB protection, is designed for intolerant skin, ishypoallergenic, fragrance- and paraben-free and non-comedogenic. It can be used on sensitive areas such as nose,cheeks, lips and scars

Avene thermal water (Avene aqua), titanium dioxide, isodecylneopentanoate, triethylhexanoin, C12-15 alkyl benzoate,cyclomethicone, glycerin, polyglyceryl-4 isostearate, C30-45alkyl methicone, cetyl PEG/PPG-10/1 dimethicone, hexyllaurate, alumina, water (aqua), stearic acid, hydrogenatedcastor oil, caprylic/capric triglyceride, disodium EDTA, ironoxides (CI 77492), iron oxides (CI 77491), octyldodecanol,silica dimethyl silylate, sodium chloride, sodium myristoylglutamate, sorbic acid, tocopheryl glucoside,triethoxycaprylylsilane, xanthan gum, tetradibutylpentaerithrityl hydroxyhydrocinnamate

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