Should be onUp to hear patient button pressesDown to mute. In either case the #1 and #2 lights should light with each button press.Leave the 5 to the right alone.

If I hear a sound this means that the patient is pressing the button hard enough.

Should be on

Left switch upMiddle switch downRight switch is for resetAlways reset if theleft or middle switchis changed

Red button is for patient’s volume. Adjust for patient. Base treble balance usually can be left alone.

Controls the speakers in the control room, i.e. to monitor whatthe subject hears. Press

to speak with patientToggle down for

computer audio.Middle would turn off.

These 3 should be off.

Scan Trigger button

fMRI Console

USB cable connecting computer to patch panel.

Lower right on computer

Lower left on control panel

Cabling

L & R audio cables from patch panel to back of fMRI console

Subject Setup

• All scans are at MR1.• Technologist will screen subject for MR safety.• Copy of signed consent required.• Technologist will position subject in scanner – 32 channel head coil.• Standard piezoelectric audio headset required.• Two button boxes required – button 1 in left hand, button 2 in right

hand.• Assign subject a number and add name and number to table. You

may want to have the tech use this number in the Subject Name field on the scanner.

• Technologist will load your Examcard titled “User Defined 1/Lesser/Math_Spell”.

• The technologist will run the Survey scan, SENSE Reference scan and MPRAGE anatomical scan.

• You can proceed to login to the PC and start up the Mental Arithmetic paradigm if not already done. Hold at the “Test Sound Buttons?” prompt (see next slide).

1. Login to the computer: user icon Ronald Lesser, password as set.

2. On the computer desktop double click MentalArithmetic.3. Enter the Subject Number – assign new number to each

subject, keep a table matching subject name and subject number

4. Enter Session Number – usually 1. If same subject comes back, use same Subject Number and next Session Number.

5. Test Sound & Buttons? Yes for first try to allow sound test and verify buttons work. No for subsequent runs when you are sure sounds and buttons are set. Wait here until the initial scans are complete.

6. When scans are done, instruct the subject to listen and press OK

2

3

4

5

Run Mental Arithmetic

Sound and Button Test

• Display above appears and sound plays with test math problem.• Ask subject whether they heard the sound. If not, turn up the volume using the

large red control on the console.• Have subject press button 1 in left hand. Sound will play again if the button press is

detected. If no new sound, check button switches, connections and whether subject is pressing hard enough.

• When button is detected and sound plays, verify again that it is loud but comfortable and adjust if necessary.

• Have subject press button 2 in right hand. Sound will play. Verify button 2 was detected.

• Repeat button presses and sound checks until all is operating properly. You can trigger sounds yourself by pressing button 1 or 2 on the fMRI console.

• Press the Scan Trigger button or button 6 to finish the test and verify trigger is working. It should advance to the “Wait for the test to begin” screen.

Never push thisbutton. It would be used only if the life of a person was in danger due to being trapped by a large metal object against the scanner. Pushing results in thousands of dollars in repairs and downtime.

Push the Scan Trigger button or this button (#6) when done with the sound and button press practices and then “Wait for the test to begin” appears on the screen in the fMRI room.

Mental Arithmetic Test Startup

• After pressing the Scan Trigger button, the paradigm is ready to begin. It waits for the trigger to come from the scanner.

• Have the technologist start the scan MentalArithmetic. Watch for a button 6 press after about 10 seconds of scanner sounds. This is the scanner trigger – the paradigm should begin with instructions for 5 seconds followed by the first audio math problem and 2 answers on screen.

• Watch that the subject is responding with button presses. • The entire test will run without any interaction.• “The End” will appear and scanning should end simultaneously.• Press any keyboard key to finish the test.

8 Easy problems 5 sec each, 40 sec

8 Hard problems5 sec each, 40 sec

8 odd/even problems5 sec each, 40 sec

Scan trigger starts the paradigm 5 sec

5 sec

5 secRepeats 2 more timesPress key to end

Total time 405 sec6:45

Mental Arithmetic Flow

135 sec/block 2:15

1. On the computer desktop double click Spelling. 2. Enter the Subject Number – use the same number as used

for the Mental Arithmetic.3. Enter Session Number – usually 1. If same subject comes

back, use same Subject Number and new Session Number.4. Test Sound & Buttons? You may want to skip the tests if the

subject could hear well and buttons were working during the Mental Arithmetic. If you skip the test, the “Wait for test to begin” screen comes up.

Run Spelling

Spelling Test Startup

• After skipping the sound & button tests or pressing the Scan Trigger button to end the tests, the paradigm is ready to begin. It waits for the trigger to come from the scanner.

• Have the technologist start the scan Spelling. Watch for a button 6 press after about 10 seconds of scanner sounds. This is the scanner trigger – the paradigm should begin with instructions for 5 seconds followed by the first audio spelling problem and 2 answers on screen.

• Watch that the subject is responding with button presses. • The entire test will run without any interaction.• “The End” will appear and scanning should end simultaneously.• Press any keyboard key to finish the test.

Extra pictures - ignore