Shingles ( Herpes Zoster)

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<ul><li>1.SHINGLESSHINGLES Presented By : Areeba AzeemPresented By : Areeba Azeem </li></ul> <p>2. ShinglesShingles Also known as Herpes Zoster. An acute viral infection of the nerve cells and surrounding skin. Characterized by a rash of blisters, can be very painful but is not life-threatening. Caused by the varicella zoster virus that also causes chickenpox. 3. Shingles usually appears, band of blisters on one side of the chest or back, but it can occur anywhere on the body, including on the face and near the eyes. 4. Varicella-zoster virus Varicella-zoster virus (VZV) infection causes two clinically distinct forms of disease: 1. Varicella (chickenpox) 1. Herpes zoster (shingles) 5. Herpes virus (DNA) Primary infection results in varicella (chickenpox) Recurrent infection results in herpes zoster (shingles) 6. Shingles EpidemiologyShingles Epidemiology 7. PathophysiologyPathophysiology 8. Clinical presentation of shinglesClinical presentation of shingles Initial prodromal stageInitial prodromal stage The first signs of shingles may include Headache Feeling generally unwell Myalgia Fever 9. Acute stage A rash will begin to develop, often causing a pain. Itching or tingling sensation in the area of the affected nerve. A fluid filled painful rash then develops a few days after and commonly occurs either on one side of the face or body. Fluid-filled blisters that break open and crust over in 7-10 days and this clears within 2-4 weeks. 10. Complications Of ShinglesComplications Of Shingles 1.1. Post herpetic neuralgia (PHN)Post herpetic neuralgia (PHN) Post herpetic neuralgia can cause severe nerve pain that persists after the rash. PHN occurs most often in elderly people and in people whose immune systems have been compromised. 2.2. Ophthalmic shinglesOphthalmic shingles Shingles in or around an eye can cause painful eye infections that may result in vision loss. 11. 3.3. Ramsay Hunt syndromeRamsay Hunt syndrome Otherwise known as herpes zoster oticus, is inflammation of several of the nerves that come out of the brain. The symptoms of Ramsay Hunt syndrome are facial paralysis, ear pain. 4. Encephalitis 5. Hearing problems 6. Bacterial infections on the skin. 12. Treatment Of Herpes ZosterTreatment Of Herpes Zoster 13. Pharmacologic ManagementPharmacologic Management 14. Management of acute herpes zosterManagement of acute herpes zoster Antiviral medicationAntiviral medication to reducepain and complications. Should bestarted within 24 hoursof first symptom .Thesemedications include: Acyclovir (Zovirax) Valacyclovir (Valtrex) Famciclovir (Famvir) 15. Management of Post herpetic Neuralgia Tricyclic antidepressants, such as amitriptyline. Opoids, such asmethadone, morphine. Lidocainepatch. Anticonvulsants, such asgabapentin. Capsaicincream. Topical anesthetics, including benzocaine. 16. Non-pharmacologic treatment Apply cool water compressesto the skin or soak in abathtub filled with cool water Add finely ground oatmeal to the bathtub. Apply calaminelotion to theaffected areas. Trim your fingernailsto avoid infection. Wear loose-fitting clothing. 17. Prevention o Shingles vaccine (Zo stavaxShingles vaccine (Zo stavax )) It is given to people 60 years of age and older who have already had the chickenpox. The shingles vaccine is a live vaccine given as a single injection, usually in the upper arm. The most common side effects of the shingles vaccine are redness, pain, tenderness and swelling at the injection site, and headaches. 18. References:References: http://www.nytimes.com/health/guides/disease/herpes-zoster/treatment- for-an-acute-shingles-attack.html http://www.wikihow.com/Treat-Shingles-(Herpes-Zoster) https://umm.edu/health/medical/altmed/condition/varicellazoster-virus http://www.nhs.uk/Conditions/Shingles/Pages/Treatment.aspx http://www.cdc.gov/vaccines/vpd-vac/shingles/hcp-vaccination.htm http://www.nhs.uk/Conditions/Shingles/Pages/Treatment.aspx http://www.mayoclinic.org/diseasesconditions/shingles/basics/definition/c on-20019574 19. Thank You..!!!Thank You..!!! </p>

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