seer cancer statistics review 1975-2015

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SEER Cancer Statistics Review 1975-2015 National Cancer Institute Joinpoint Regression Program Version 4.6, February 2018, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/). The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130). a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta). b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry). c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention. d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint. e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry. The Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma. g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties. * The APC/AAPC is significantly different from zero (p<.05). - Joinpoint regression line analysis could not be performed on data series. JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPC d Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15 SEER 9 Delay-Adjusted Incidence a , 1975-2015 All Races 1975-77 6.3 1977-80 -6.5 1980-97 2.4* 1997-09 6.7* 2009-15 1.5* 3.2* 1.5* White 1975-77 7.5 1977-80 -6.7 1980-97 2.7* 1997-09 7.0* 2009-15 1.4* 3.2* 1.4* Black 1975-95 0.8 1995-12 6.3* 2012-15 -1.9 3.5* 0.1 SEER 13 Delay-Adjusted Incidence b , 1992-2015 All Races 1992-98 2.9* 1998-09 6.6* 2009-15 1.6* 3.3* 1.6* White 1992-98 3.6* 1998-09 6.8* 2009-15 1.5* 3.2* 1.5* Black 1992-95 -4.4 1995-11 6.8* 2011-15 -0.5 3.5* -0.5 SEER 9 Observed Incidence a , 1975-2015 All Races 1975-77 6.3 1977-80 -6.5 1980-97 2.4* 1997-09 6.7* 2009-15 1.3* 3.1* 1.3* White 1975-77 7.5 1977-80 -6.7 1980-97 2.7* 1997-09 7.0* 2009-15 1.2* 3.1* 1.2* Black 1975-95 0.9 1995-12 6.2* 2012-15 -2.6 3.2* -0.4 SEER 13 Observed Incidence b , 1992-2015 All Races 1992-98 2.9* 1998-09 6.6* 2009-15 1.5* 3.1* 1.5* White 1992-98 3.6* 1998-09 6.8* 2009-15 1.3* 3.1* 1.3* White NH ef 1992-98 4.4* 1998-09 7.0* 2009-15 1.1* 3.0* 1.1* Black 1992-95 -4.2 1995-11 6.7* 2011-15 -1.0 3.2* -1.0 Black NH ef 1992-95 -4.6 1995-11 6.9* 2011-15 -0.9 3.3* -0.9 API e 1992-04 1.9* 2004-09 7.6* 2009-15 1.0 3.1* 1.0 AI/AN eg 1992-15 3.7* 3.7* 3.7* Hispanic f 1992-95 -5.3 1995-13 5.0* 2013-15 -1.7 3.5* 1.6 U.S. Cancer Mortality c , 1975-2015 All Races 1975-88 -2.1* 1988-15 0.7* 0.7* 0.7* White 1975-88 -2.2* 1988-15 0.7* 0.7* 0.7* Black 1975-15 0.1 0.1 0.1 U.S. Cancer Mortality c , 1992-2015 All Races 1992-15 0.7* 0.7* 0.7* White 1992-15 0.7* 0.7* 0.7* White NH ef 1992-15 0.7* 0.7* 0.7* Black 1992-15 0.9* 0.9* 0.9* Black NH ef 1992-15 1.0* 1.0* 1.0* API e 1992-15 -0.5 -0.5 -0.5 AI/AN eg 1992-15 0.8 0.8 0.8 Hispanic f 1992-15 0.1 0.1 0.1 Table 26.1 Cancer of the Thyroid (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2015 With up to Five Joinpoints, 1992-2015 With up to Four Joinpoints, Both Sexes by Race/Ethnicity

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Page 1: SEER Cancer Statistics Review 1975-2015

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Regression Program Version 46 February 2018 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 13 areas (SEER 9 Areas Los Angeles San Jose-Monterey Rural Georgia and the Alaska Native Registry)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native RegistryThe Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

g Data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15

SEER 9 Delay-Adjusted Incidencea 1975-2015All Races 1975-77 63 1977-80 -65 1980-97 24 1997-09 67 2009-15 15 32 15White 1975-77 75 1977-80 -67 1980-97 27 1997-09 70 2009-15 14 32 14Black 1975-95 08 1995-12 63 2012-15 -19 35 01

SEER 13 Delay-Adjusted Incidenceb 1992-2015All Races 1992-98 29 1998-09 66 2009-15 16 33 16White 1992-98 36 1998-09 68 2009-15 15 32 15Black 1992-95 -44 1995-11 68 2011-15 -05 35 -05

SEER 9 Observed Incidencea 1975-2015All Races 1975-77 63 1977-80 -65 1980-97 24 1997-09 67 2009-15 13 31 13White 1975-77 75 1977-80 -67 1980-97 27 1997-09 70 2009-15 12 31 12Black 1975-95 09 1995-12 62 2012-15 -26 32 -04

SEER 13 Observed Incidenceb 1992-2015All Races 1992-98 29 1998-09 66 2009-15 15 31 15White 1992-98 36 1998-09 68 2009-15 13 31 13White NHef 1992-98 44 1998-09 70 2009-15 11 30 11

Black 1992-95 -42 1995-11 67 2011-15 -10 32 -10Black NHef 1992-95 -46 1995-11 69 2011-15 -09 33 -09

APIe 1992-04 19 2004-09 76 2009-15 10 31 10AIANeg 1992-15 37 37 37Hispanicf 1992-95 -53 1995-13 50 2013-15 -17 35 16

US Cancer Mortalityc 1975-2015All Races 1975-88 -21 1988-15 07 07 07White 1975-88 -22 1988-15 07 07 07Black 1975-15 01 01 01

US Cancer Mortalityc 1992-2015All Races 1992-15 07 07 07White 1992-15 07 07 07White NHef 1992-15 07 07 07

Black 1992-15 09 09 09Black NHef 1992-15 10 10 10

APIe 1992-15 -05 -05 -05AIANeg 1992-15 08 08 08Hispanicf 1992-15 01 01 01

Table 261Cancer of the Thyroid (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program1975-2015 With up to Five Joinpoints 1992-2015 With up to Four Joinpoints

Both Sexes by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Regression Program Version 46 February 2018 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 13 areas (SEER 9 Areas Los Angeles San Jose-Monterey Rural Georgia and the Alaska Native Registry)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native RegistryThe Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

g Data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15

SEER 9 Delay-Adjusted Incidencea 1975-2015All Races 1975-80 -46 1980-97 18 1997-12 55 2012-15 -11 32 05White 1975-77 104 1977-80 -91 1980-98 26 1998-09 62 2009-15 23 36 23Black 1975-15 30 30 30

SEER 13 Delay-Adjusted Incidenceb 1992-2015All Races 1992-96 -14 1996-09 56 2009-15 25 36 25White 1992-96 -03 1996-09 58 2009-15 23 35 23Black 1992-15 38 38 38

SEER 9 Observed Incidencea 1975-2015All Races 1975-80 -46 1980-97 18 1997-12 54 2012-15 -14 31 03White 1975-77 104 1977-80 -91 1980-98 26 1998-09 62 2009-15 21 34 21Black 1975-15 30 30 30

SEER 13 Observed Incidenceb 1992-2015All Races 1992-96 -13 1996-09 56 2009-15 24 34 24White 1992-96 -03 1996-09 58 2009-15 21 33 21White NHef 1992-96 01 1996-09 62 2009-15 21 34 21

Black 1992-15 37 37 37Black NHef 1992-15 37 37 37

APIe 1992-03 06 2003-15 55 55 55AIANeg 1992-15 25 25 25Hispanicf 1992-15 39 39 39

US Cancer Mortalityc 1975-2015All Races 1975-83 -31 1983-15 12 12 12White 1975-84 -25 1984-15 12 12 12Black 1975-15 04 04 04

US Cancer Mortalityc 1992-2015All Races 1992-15 13 13 13White 1992-15 14 14 14White NHef 1992-15 14 14 14

Black 1992-15 13 13 13Black NHef 1992-15 14 14 14

APIe 1992-15 03 03 03AIANeg - - - -Hispanicf 1992-15 12 12 12

Table 262Cancer of the Thyroid (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program1975-2015 With up to Five Joinpoints 1992-2015 With up to Four Joinpoints

Males by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Regression Program Version 46 February 2018 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 13 areas (SEER 9 Areas Los Angeles San Jose-Monterey Rural Georgia and the Alaska Native Registry)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native RegistryThe Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

g Data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15

SEER 9 Delay-Adjusted Incidencea 1975-2015All Races 1975-77 65 1977-80 -52 1980-93 23 1993-99 44 1999-09 71 2009-15 12 31 12White 1975-81 -11 1981-93 24 1993-99 51 1999-09 74 2009-15 11 32 11Black 1975-89 -11 1989-15 55 55 55

SEER 13 Delay-Adjusted Incidenceb 1992-2015All Races 1992-99 41 1999-09 69 2009-15 14 32 14White 1992-98 44 1998-09 70 2009-15 14 32 14Black 1992-98 29 1998-11 75 2011-15 -06 38 -06

SEER 9 Observed Incidencea 1975-2015All Races 1975-77 65 1977-80 -52 1980-93 23 1993-99 45 1999-09 71 2009-15 10 30 10White 1975-81 -11 1981-93 24 1993-99 52 1999-09 74 2009-15 09 30 09Black 1975-93 02 1993-12 63 2012-15 -14 37 05

SEER 13 Observed Incidenceb 1992-2015All Races 1992-99 41 1999-09 69 2009-15 12 31 12White 1992-98 44 1998-09 70 2009-15 12 31 12White NHef 1992-99 56 1999-09 73 2009-15 08 29 08

Black 1992-98 30 1998-11 74 2011-15 -11 35 -11Black NHef 1992-98 28 1998-11 76 2011-15 -11 36 -11

APIe 1992-99 03 1999-10 53 2010-15 00 23 00AIANeg 1992-15 40 40 40Hispanicf 1992-95 -42 1995-13 51 2013-15 -13 37 19

US Cancer Mortalityc 1975-2015All Races 1975-88 -25 1988-15 03 03 03White 1975-88 -28 1988-15 03 03 03Black 1975-15 00 00 00

US Cancer Mortalityc 1992-2015All Races 1992-94 -49 1994-15 05 05 05White 1992-15 02 02 02White NHef 1992-15 02 02 02

Black 1992-15 08 08 08Black NHef 1992-15 09 09 09

APIe 1992-15 -10 -10 -10AIANeg 1992-15 -12 -12 -12Hispanicf 1992-15 -05 -05 -05

Table 263Cancer of the Thyroid (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program1975-2015 With up to Five Joinpoints 1992-2015 With up to Four Joinpoints

Females by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-1979 493 307 669 482 293 662 327 164 4631980 433 239 615 429 228 620 237 111 3431981 442 252 624 439 248 628 239 104 3441982 463 300 615 453 287 609 329 202 4341983 471 280 650 474 261 673 302 215 3771984 485 265 693 473 258 681 302 173 4081985 513 310 709 509 310 704 286 189 3661986 533 307 750 525 310 737 335 119 5091987 504 281 712 502 286 706 282 097 4301988 493 294 688 489 300 678 253 180 3211989 537 299 766 547 322 770 263 062 4141990 549 293 795 555 299 807 376 228 4911991 549 319 769 570 331 804 322 207 4201992 588 352 813 588 352 817 423 309 5181993 565 359 764 574 368 777 338 207 4561994 609 339 875 624 344 903 375 178 5351995 623 337 902 642 359 923 308 120 4611996 652 347 951 672 361 983 389 179 5801997 678 366 980 706 377 1034 398 244 5241998 699 372 1012 720 395 1041 403 150 6111999 735 387 1068 756 408 1098 459 160 7012000 762 404 1110 805 438 1177 457 218 6552001 831 434 1218 868 462 1278 493 252 6882002 924 495 1343 976 527 1429 552 285 7682003 966 472 1448 1038 506 1571 530 282 7512004 1015 524 1494 1082 555 1613 637 333 8902005 1098 581 1599 1195 648 1743 592 276 8682006 1133 586 1663 1217 637 1800 664 315 9472007 1243 613 1854 1329 657 2007 728 323 10622008 1325 659 1972 1425 707 2148 710 450 9532009 1451 710 2165 1559 775 2341 867 340 13202010 1400 667 2110 1482 729 2241 873 344 13112011 1486 744 2205 1580 801 2362 919 382 13602012 1506 808 2190 1592 870 2327 973 437 14252013 1524 781 2249 1645 846 2454 924 403 13712014 1526 777 2257 1635 833 2449 984 436 14532015 1522 776 2254 1643 864 2439 899 319 1374

Table 264Cancer of the Thyroid (Invasive)

Delay-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2015 870 466 1259 890 484 1293 550 259 7931975-1979 493 307 669 482 293 662 327 164 4631980 433 239 615 429 228 620 237 - 3431981 442 252 624 439 248 628 239 - 3441982 463 300 615 453 287 609 329 - 4341983 471 280 650 474 261 673 302 215 3771984 485 265 693 473 258 681 302 - 4081985 513 310 709 509 310 704 286 - 3661986 533 307 750 525 310 737 335 - 5091987 504 281 712 502 286 706 282 - 4301988 493 294 688 489 300 678 253 - 3211989 537 299 766 547 322 770 263 - 4141990 549 293 795 555 299 807 376 228 4911991 549 319 769 570 331 804 322 207 4201992 588 352 813 588 352 817 423 309 5181993 565 359 764 574 368 777 338 207 4561994 609 339 875 624 344 903 375 178 5351995 623 337 902 642 359 923 308 - 4611996 652 347 951 672 361 983 389 179 5801997 678 366 980 706 377 1034 398 244 5241998 699 372 1012 720 395 1041 403 150 6111999 735 387 1068 756 408 1098 459 160 7012000 762 404 1110 805 438 1177 457 218 6552001 831 434 1218 868 462 1278 493 252 6882002 924 495 1343 976 527 1429 552 285 7682003 966 472 1448 1038 506 1571 530 282 7512004 1015 524 1494 1082 555 1613 637 333 8902005 1098 581 1599 1195 648 1743 592 276 8682006 1133 586 1663 1217 637 1800 664 315 9472007 1241 612 1853 1328 656 2005 726 322 10602008 1323 658 1968 1422 706 2144 707 448 9482009 1448 708 2159 1554 773 2334 861 338 13112010 1395 665 2102 1476 726 2232 865 340 12982011 1480 741 2196 1572 797 2350 908 378 13442012 1498 804 2179 1583 865 2313 959 431 14042013 1514 776 2233 1631 839 2434 910 397 13512014 1514 771 2238 1618 824 2423 962 425 14212015 1503 766 2226 1614 849 2397 874 310 1336

Table 265Cancer of the Thyroid (Invasive)

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2015 048 045 050 048 046 048 048 035 0561975-1979 055 044 061 055 045 061 052 038 0621980 048 038 053 049 040 054 042 029 0511981 050 042 055 050 043 054 048 026 0621982 048 037 053 047 037 053 048 038 0541983 044 034 050 045 035 050 041 028 0491984 047 038 052 047 039 051 047 - 0641985 045 039 048 044 039 046 049 034 0581986 046 039 049 045 039 049 048 034 0571987 045 040 048 045 041 047 048 033 0581988 044 041 045 044 042 044 044 033 0501989 044 041 044 043 041 043 051 040 0561990 044 037 048 044 038 047 045 030 0541991 043 038 046 042 039 043 050 037 0581992 046 038 050 046 039 048 041 030 0481993 046 039 050 046 040 048 046 026 0581994 042 038 044 042 038 044 037 030 0401995 044 041 044 044 043 044 040 027 0461996 045 042 047 045 043 046 044 033 0491997 046 045 046 045 045 044 049 037 0551998 044 038 047 043 039 045 043 027 0531999 045 044 045 045 045 044 044 039 0472000 048 047 048 047 048 045 051 034 0592001 048 047 048 047 048 046 051 041 0582002 048 045 048 048 046 048 048 039 0522003 045 043 046 046 045 046 038 029 0442004 048 047 047 048 048 047 045 040 0482005 048 048 049 048 050 046 051 030 0642006 049 046 051 050 048 050 047 028 0602007 050 051 048 048 051 046 050 040 0562008 052 050 052 052 052 051 046 040 0512009 052 051 052 051 052 050 057 041 0662010 051 050 051 050 051 048 049 045 0532011 051 052 049 051 054 048 044 032 0512012 048 051 046 048 052 045 049 041 0542013 052 053 050 051 054 048 052 039 0612014 050 049 050 050 052 048 056 038 0662015 051 054 048 050 055 046 049 041 053

Table 266Cancer of the Thyroid (Invasive)

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a SEER 18 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2011-2015All ages 145 73 214 153 78 228 89 38 134Under 65 132 58 205 141 63 220 76 27 12065 and over 231 175 278 235 182 282 181 114 228

All ages (WHO world std)c 128 62 192 135 66 205 76 31 116

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 02 - 02 02 - 03 - - -10-14 09 05 14 11 05 16 - - -15-19 31 09 53 34 10 60 11 - 1820-24 62 20 107 71 23 124 17 - 3225-29 105 35 179 117 40 200 42 11 7230-34 160 57 264 175 63 291 67 16 11335-39 201 74 328 214 78 354 111 32 18240-44 220 91 347 230 97 367 146 48 23345-49 236 109 362 249 117 382 144 47 23150-54 256 123 385 270 133 407 152 59 23455-59 262 144 373 275 154 393 172 89 24360-64 260 163 348 267 174 355 203 91 29565-69 290 199 370 294 207 373 225 127 30070-74 259 195 313 268 204 323 195 131 24175-79 231 177 272 237 184 280 179 118 22080-84 174 157 186 175 161 186 129 106 14185+ 110 96 117 107 99 111 122 - 153

US MortalityAge at DeathAge-Adjusted Rates 2011-2015All ages 05 05 05 05 05 05 05 04 06Under 65 01 02 01 01 02 01 02 01 0265 and over 30 30 29 29 30 28 29 21 33

All ages (WHO world std)c 03 04 03 03 04 03 03 03 04

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 00 - - 00 - - - - -30-34 00 00 - 00 - - - - -35-39 00 00 00 00 00 - - - -40-44 01 01 01 01 01 01 - - -45-49 02 03 02 02 03 01 03 03 0350-54 04 04 03 04 05 03 04 03 0555-59 06 07 06 06 07 05 05 04 0660-64 11 12 10 11 12 09 12 09 1465-69 16 17 15 16 17 14 16 14 1870-74 22 22 21 21 22 21 25 20 2875-79 31 32 31 31 33 30 30 28 3180-84 43 42 43 42 43 41 37 23 4585+ 57 54 59 57 56 57 54 26 66

Table 267Cancer of the Thyroid (Invasive)

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2015 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2015

d Period survival provides a 2014 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2008-2014 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 83 75 87 - - -1970-1973a - - - 86 82 87 - - -1975-1977b 921 911 925 918 907 922 898 - 9101978-1980b 921 872 936 915 875 927 902 680h 9551981-1983b 936 922 939 931 909 937 964 1000 9321984-1986b 932 898 943 932 894 944 893 855g 9031987-1989b 944 916 952 941 916 950 923 912g 9231990-1992b 943 905 955 949 916 960 859 845g 8631993-1995b 954 916 967 956 915 969 932 878g 9431996-1998b 956 910 969 959 913 973 951 865g 9661999-2001b 965 943 971 968 949 974 920 884g 9242002-2004b 973 939 982 974 941 983 959 942 9602005-2007b 979 961 985 980 961 986 963 915 9692008-2014b 983f 960f 989f 986f 965f 992f 970f 913 979f

5-Year Period Survival (Percent)cd

2014 982 958 989 984 961 990 969 928 974

Stage Distribution () 2008-2014ce

All StagesNumber of cases 74280 17072 57208 59623 14147 45476 5139 909 4230Percent 100 100 100 100 100 100 100 100 100Localized 67 58 70 67 58 70 80 72 81Regional 27 33 25 27 34 25 14 18 13Distant 4 7 3 4 6 3 4 8 4UnstagedUnknown 2 2 2 2 2 2 2 2 2

5-Year Relative Survival (Percent) 2008-2014c

Age at DiagnosisAges lt45 997 991 998 997 993 998 992 965 995Ages 45-54 988 962 995 988 964 995 990 959 995Ages 55-64 980 952 989 983 953 992 956 920 963Ages 65-74 963 917 974 966 923 977 939 822g 965Ages 75+ 863 847 867 884 863 888 754 728g 739Ages lt65 991 971 996 991 972 996 983 952 990Ages 65+ 932 896 943 942 905 949 889 824g 903

StageeAll Stages 981 956 988 983 958 990 972 929 977Localized 999 998 1000 999 998 1000 998 989 999Regional 980 964 987 982 966 989 944 896 958Distant 555 509 583 558 507 592 470 424g 487UnstagedUnknown 891 836 909 884 845 897 887 - 915

Table 268Cancer of the Thyroid (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 949 951 959 962 967 968 964 977 972 976 976 971 979 983 977 985 985 983 988 989 987 988 983 9872-year 935 945 952 957 961 966 962 971 971 970 974 971 979 979 973 984 981 982 987 986 986 984 9823-year 929 937 948 953 960 960 962 969 971 969 970 971 977 979 973 983 980 982 987 985 986 9844-year 925 934 943 950 959 954 956 963 970 969 970 971 974 977 973 983 979 980 987 984 9865-year 921 933 941 947 958 949 953 962 969 963 962 971 973 973 973 982 979 978 987 9816-year 916 931 938 943 958 948 952 958 964 963 962 967 970 972 973 982 979 978 9877-year 914 927 934 942 956 945 952 958 962 961 961 965 968 969 973 981 979 9788-year 911 926 933 941 955 942 951 958 960 959 959 963 967 968 973 980 9799-year 907 923 931 939 955 937 949 958 956 959 954 963 967 968 973 98010-year 905 920 928 936 951 936 949 958 954 958 954 963 967 967 97311-year 903 917 927 933 950 933 949 958 950 958 954 961 967 96512-year 903 914 926 930 950 930 949 958 948 958 954 959 96713-year 900 912 925 930 950 928 949 950 947 958 954 95914-year 899 912 924 927 950 926 949 946 946 958 95415-year 897 907 923 923 943 924 949 941 945 95816-year 896 906 923 922 938 924 949 938 94517-year 895 906 922 922 938 923 949 93718-year 893 905 922 921 938 923 94319-year 892 905 919 921 938 92320-year 892 905 919 921 938

Table 269Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 946 925 948 946 934 937 918 972 965 963 961 951 956 967 971 964 973 968 983 978 973 979 967 9712-year 925 920 937 932 919 934 909 954 962 949 955 949 953 951 956 961 965 961 982 963 969 972 9643-year 915 908 935 924 917 921 909 947 962 949 942 949 942 948 956 961 965 961 982 961 967 9684-year 905 904 921 919 914 917 895 937 962 949 936 946 935 943 956 961 965 957 982 956 9675-year 899 902 916 910 912 898 882 937 962 938 924 943 932 940 956 957 963 951 980 9436-year 896 898 911 906 903 898 880 935 958 938 920 938 917 940 956 957 963 951 9787-year 894 893 900 904 887 895 880 933 954 934 919 924 917 928 956 953 963 9498-year 893 893 896 901 887 885 878 933 952 934 911 915 917 925 953 953 9639-year 888 886 885 899 887 867 869 933 930 934 898 910 917 921 953 95310-year 883 879 885 897 874 864 869 933 926 934 896 910 917 915 94911-year 875 872 884 895 862 848 865 933 926 934 896 902 917 91512-year 875 864 883 887 860 841 865 931 926 934 893 899 91713-year 873 862 878 882 860 831 865 931 926 927 893 89914-year 873 862 877 878 858 827 865 931 926 927 89315-year 867 854 877 872 858 827 865 931 926 92416-year 866 853 877 868 858 827 865 923 92617-year 866 849 877 868 858 827 865 91818-year 866 846 877 865 858 827 86019-year 866 846 877 864 858 82220-year 866 846 877 864 858

Table 2610Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 950 960 963 968 978 977 977 979 974 980 980 977 986 988 979 990 989 987 989 991 991 991 988 9912-year 939 953 957 966 974 975 977 976 974 977 980 977 985 987 979 990 985 987 988 991 991 988 9873-year 933 947 952 963 973 971 977 975 974 975 977 977 985 987 979 989 985 987 988 991 991 9884-year 931 944 950 961 973 965 975 971 972 975 977 977 985 987 979 989 983 986 987 991 9905-year 927 943 949 959 972 964 974 969 969 970 973 977 984 983 979 989 983 986 987 9906-year 923 942 947 955 972 961 973 965 965 970 973 976 983 981 979 989 983 986 9877-year 921 938 945 954 972 959 973 965 963 970 973 976 981 980 979 989 983 9858-year 917 937 945 954 972 959 973 965 962 966 973 976 980 980 979 987 9839-year 913 936 945 953 972 958 973 965 962 966 970 976 979 980 979 98710-year 912 934 942 949 972 957 973 965 960 964 970 976 977 980 97911-year 912 932 940 946 972 957 973 965 958 964 970 976 977 97912-year 911 931 940 945 972 955 973 965 952 964 970 976 97713-year 909 929 940 944 972 955 973 955 949 964 970 97614-year 908 928 939 943 972 955 973 949 946 964 97015-year 907 924 938 940 967 950 973 943 944 96416-year 906 923 937 939 958 950 973 942 94417-year 904 923 936 939 958 950 971 94118-year 899 923 935 938 958 950 96719-year 898 923 932 938 958 95020-year 898 923 932 938 958

Table 2611Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 002 011 122 006 Asian 0 000 002 010 128 011

10 002 011 029 123 006 Pacific 10 002 010 027 129 011

20 009 027 049 121 006 Islander 20 008 024 047 127 011

30 018 040 065 114 007 30 017 039 063 120 011

40 023 047 072 097 007 40 022 046 072 104 011

50 025 050 068 077 007 50 024 051 070 083 011

60 026 046 053 054 006 60 027 047 058 060 011

70 022 030 - 032 006 70 021 032 - 035 010

80 011 - - 013 005 80 013 - - 017 008

White 0 000 003 012 128 006 American 0 000 002 007 083 007

10 003 012 031 129 006 Indian 10 002 007 018 084 007

20 010 029 052 127 006 Alaska 20 005 016 026 083 007

30 019 043 069 118 006 Nativea 30 011 021 036 079 007

40 024 050 074 100 006 40 010 026 043 070 007

50 027 052 071 079 006 50 016 034 048 063 008

60 027 047 054 055 006 60 019 034 047 050 007

70 022 031 - 032 006 70 017 032 - 035 007

80 011 - - 013 005 80 020 - - 024 009

Black 0 000 001 004 074 006 Hispanicb 0 000 002 009 114 009

10 001 004 012 076 006 10 002 009 023 115 009

20 003 012 026 075 006 20 007 021 040 113 009

30 009 023 038 073 006 30 014 033 055 107 009

40 015 030 048 066 006 40 019 042 065 094 010

50 016 034 046 053 006 50 023 047 067 077 010

60 020 033 039 040 006 60 025 045 053 056 009

70 016 023 - 025 006 70 022 031 - 034 009

80 010 - - 013 005 80 011 - - 014 007

Table 2612

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 001 004 064 006 Asian 0 000 001 004 067 008

10 001 004 010 065 006 Pacific 10 001 004 010 067 008

20 003 009 019 064 006 Islander 20 003 009 020 066 008

30 007 016 029 062 006 30 007 017 028 064 008

40 010 022 038 056 006 40 010 021 036 058 008

50 013 029 042 048 006 50 011 026 039 048 008

60 017 031 037 038 006 60 016 029 038 038 008

70 016 023 - 024 005 70 015 024 - 025 007

80 010 - - 011 004 80 011 - - 012 006

White 0 000 001 004 068 006 American 0 000 001 003 034 006

10 001 004 011 069 006 Indian 10 001 003 006 035 006

20 003 010 020 068 006 Alaska 20 002 005 008 034 006

30 007 017 031 066 006 Nativea 30 003 006 010 033 006

40 010 024 040 060 006 40 002 007 015 030 006

50 014 031 045 051 006 50 005 013 022 030 007

60 018 033 039 039 006 60 009 019 027 027 007

70 017 024 - 025 005 70 011 020 - 021 007

80 010 - - 011 004 80 013 - - 014 008

Black 0 000 000 001 031 003 Hispanicb 0 000 001 003 050 007

10 000 001 004 031 004 10 001 003 007 050 007

20 001 003 008 031 004 20 002 006 012 050 007

30 003 007 014 031 004 30 004 011 020 048 007

40 004 012 020 029 004 40 006 016 028 045 007

50 008 016 023 026 004 50 010 022 033 039 007

60 010 017 021 021 004 60 013 025 030 031 007

70 010 014 - 014 003 70 013 019 - 020 006

80 007 - - 007 002 80 008 - - 010 005

Table 2613

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 004 019 181 007 Asian 0 000 003 016 183 013

10 004 018 048 182 007 Pacific 10 003 016 042 184 013

20 015 044 079 179 007 Islander 20 013 039 072 181 013

30 030 065 101 165 007 30 026 059 094 169 013

40 036 072 105 137 007 40 033 068 104 144 013

50 037 071 094 104 007 50 035 071 096 112 013

60 035 059 068 070 007 60 037 062 074 079 013

70 027 036 - 038 006 70 027 039 - 044 012

80 012 - - 015 005 80 015 - - 020 009

White 0 000 004 021 190 007 American 0 000 003 011 132 008

10 004 021 053 192 007 Indian 10 002 011 030 133 008

20 017 049 086 188 007 Alaska 20 009 027 044 131 008

30 032 070 108 172 007 Nativea 30 019 036 062 124 008

40 038 076 109 141 007 40 017 044 069 107 008

50 039 073 097 106 007 50 027 054 073 093 008

60 035 060 069 070 007 60 028 048 065 069 007

70 027 037 - 038 006 70 022 041 - 046 007

80 012 - - 014 005 80 024 - - 030 008

Black 0 000 001 007 114 008 Hispanicb 0 000 004 017 179 011

10 001 007 021 116 008 10 004 017 041 180 011

20 006 020 043 116 008 20 013 038 069 177 011

30 015 038 061 111 008 30 025 056 092 165 011

40 024 047 072 098 008 40 031 068 102 141 011

50 024 050 067 076 008 50 037 072 098 111 011

60 028 046 054 056 008 60 036 063 074 077 011

70 021 030 - 033 008 70 030 041 - 044 010

80 012 - - 016 006 80 014 - - 017 008

Table 2614

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

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1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

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ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

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Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

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0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

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0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

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Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 2: SEER Cancer Statistics Review 1975-2015

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Joinpoint Regression Program Version 46 February 2018 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 13 areas (SEER 9 Areas Los Angeles San Jose-Monterey Rural Georgia and the Alaska Native Registry)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native RegistryThe Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

g Data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15

SEER 9 Delay-Adjusted Incidencea 1975-2015All Races 1975-80 -46 1980-97 18 1997-12 55 2012-15 -11 32 05White 1975-77 104 1977-80 -91 1980-98 26 1998-09 62 2009-15 23 36 23Black 1975-15 30 30 30

SEER 13 Delay-Adjusted Incidenceb 1992-2015All Races 1992-96 -14 1996-09 56 2009-15 25 36 25White 1992-96 -03 1996-09 58 2009-15 23 35 23Black 1992-15 38 38 38

SEER 9 Observed Incidencea 1975-2015All Races 1975-80 -46 1980-97 18 1997-12 54 2012-15 -14 31 03White 1975-77 104 1977-80 -91 1980-98 26 1998-09 62 2009-15 21 34 21Black 1975-15 30 30 30

SEER 13 Observed Incidenceb 1992-2015All Races 1992-96 -13 1996-09 56 2009-15 24 34 24White 1992-96 -03 1996-09 58 2009-15 21 33 21White NHef 1992-96 01 1996-09 62 2009-15 21 34 21

Black 1992-15 37 37 37Black NHef 1992-15 37 37 37

APIe 1992-03 06 2003-15 55 55 55AIANeg 1992-15 25 25 25Hispanicf 1992-15 39 39 39

US Cancer Mortalityc 1975-2015All Races 1975-83 -31 1983-15 12 12 12White 1975-84 -25 1984-15 12 12 12Black 1975-15 04 04 04

US Cancer Mortalityc 1992-2015All Races 1992-15 13 13 13White 1992-15 14 14 14White NHef 1992-15 14 14 14

Black 1992-15 13 13 13Black NHef 1992-15 14 14 14

APIe 1992-15 03 03 03AIANeg - - - -Hispanicf 1992-15 12 12 12

Table 262Cancer of the Thyroid (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program1975-2015 With up to Five Joinpoints 1992-2015 With up to Four Joinpoints

Males by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Regression Program Version 46 February 2018 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 13 areas (SEER 9 Areas Los Angeles San Jose-Monterey Rural Georgia and the Alaska Native Registry)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native RegistryThe Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

g Data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15

SEER 9 Delay-Adjusted Incidencea 1975-2015All Races 1975-77 65 1977-80 -52 1980-93 23 1993-99 44 1999-09 71 2009-15 12 31 12White 1975-81 -11 1981-93 24 1993-99 51 1999-09 74 2009-15 11 32 11Black 1975-89 -11 1989-15 55 55 55

SEER 13 Delay-Adjusted Incidenceb 1992-2015All Races 1992-99 41 1999-09 69 2009-15 14 32 14White 1992-98 44 1998-09 70 2009-15 14 32 14Black 1992-98 29 1998-11 75 2011-15 -06 38 -06

SEER 9 Observed Incidencea 1975-2015All Races 1975-77 65 1977-80 -52 1980-93 23 1993-99 45 1999-09 71 2009-15 10 30 10White 1975-81 -11 1981-93 24 1993-99 52 1999-09 74 2009-15 09 30 09Black 1975-93 02 1993-12 63 2012-15 -14 37 05

SEER 13 Observed Incidenceb 1992-2015All Races 1992-99 41 1999-09 69 2009-15 12 31 12White 1992-98 44 1998-09 70 2009-15 12 31 12White NHef 1992-99 56 1999-09 73 2009-15 08 29 08

Black 1992-98 30 1998-11 74 2011-15 -11 35 -11Black NHef 1992-98 28 1998-11 76 2011-15 -11 36 -11

APIe 1992-99 03 1999-10 53 2010-15 00 23 00AIANeg 1992-15 40 40 40Hispanicf 1992-95 -42 1995-13 51 2013-15 -13 37 19

US Cancer Mortalityc 1975-2015All Races 1975-88 -25 1988-15 03 03 03White 1975-88 -28 1988-15 03 03 03Black 1975-15 00 00 00

US Cancer Mortalityc 1992-2015All Races 1992-94 -49 1994-15 05 05 05White 1992-15 02 02 02White NHef 1992-15 02 02 02

Black 1992-15 08 08 08Black NHef 1992-15 09 09 09

APIe 1992-15 -10 -10 -10AIANeg 1992-15 -12 -12 -12Hispanicf 1992-15 -05 -05 -05

Table 263Cancer of the Thyroid (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program1975-2015 With up to Five Joinpoints 1992-2015 With up to Four Joinpoints

Females by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-1979 493 307 669 482 293 662 327 164 4631980 433 239 615 429 228 620 237 111 3431981 442 252 624 439 248 628 239 104 3441982 463 300 615 453 287 609 329 202 4341983 471 280 650 474 261 673 302 215 3771984 485 265 693 473 258 681 302 173 4081985 513 310 709 509 310 704 286 189 3661986 533 307 750 525 310 737 335 119 5091987 504 281 712 502 286 706 282 097 4301988 493 294 688 489 300 678 253 180 3211989 537 299 766 547 322 770 263 062 4141990 549 293 795 555 299 807 376 228 4911991 549 319 769 570 331 804 322 207 4201992 588 352 813 588 352 817 423 309 5181993 565 359 764 574 368 777 338 207 4561994 609 339 875 624 344 903 375 178 5351995 623 337 902 642 359 923 308 120 4611996 652 347 951 672 361 983 389 179 5801997 678 366 980 706 377 1034 398 244 5241998 699 372 1012 720 395 1041 403 150 6111999 735 387 1068 756 408 1098 459 160 7012000 762 404 1110 805 438 1177 457 218 6552001 831 434 1218 868 462 1278 493 252 6882002 924 495 1343 976 527 1429 552 285 7682003 966 472 1448 1038 506 1571 530 282 7512004 1015 524 1494 1082 555 1613 637 333 8902005 1098 581 1599 1195 648 1743 592 276 8682006 1133 586 1663 1217 637 1800 664 315 9472007 1243 613 1854 1329 657 2007 728 323 10622008 1325 659 1972 1425 707 2148 710 450 9532009 1451 710 2165 1559 775 2341 867 340 13202010 1400 667 2110 1482 729 2241 873 344 13112011 1486 744 2205 1580 801 2362 919 382 13602012 1506 808 2190 1592 870 2327 973 437 14252013 1524 781 2249 1645 846 2454 924 403 13712014 1526 777 2257 1635 833 2449 984 436 14532015 1522 776 2254 1643 864 2439 899 319 1374

Table 264Cancer of the Thyroid (Invasive)

Delay-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2015 870 466 1259 890 484 1293 550 259 7931975-1979 493 307 669 482 293 662 327 164 4631980 433 239 615 429 228 620 237 - 3431981 442 252 624 439 248 628 239 - 3441982 463 300 615 453 287 609 329 - 4341983 471 280 650 474 261 673 302 215 3771984 485 265 693 473 258 681 302 - 4081985 513 310 709 509 310 704 286 - 3661986 533 307 750 525 310 737 335 - 5091987 504 281 712 502 286 706 282 - 4301988 493 294 688 489 300 678 253 - 3211989 537 299 766 547 322 770 263 - 4141990 549 293 795 555 299 807 376 228 4911991 549 319 769 570 331 804 322 207 4201992 588 352 813 588 352 817 423 309 5181993 565 359 764 574 368 777 338 207 4561994 609 339 875 624 344 903 375 178 5351995 623 337 902 642 359 923 308 - 4611996 652 347 951 672 361 983 389 179 5801997 678 366 980 706 377 1034 398 244 5241998 699 372 1012 720 395 1041 403 150 6111999 735 387 1068 756 408 1098 459 160 7012000 762 404 1110 805 438 1177 457 218 6552001 831 434 1218 868 462 1278 493 252 6882002 924 495 1343 976 527 1429 552 285 7682003 966 472 1448 1038 506 1571 530 282 7512004 1015 524 1494 1082 555 1613 637 333 8902005 1098 581 1599 1195 648 1743 592 276 8682006 1133 586 1663 1217 637 1800 664 315 9472007 1241 612 1853 1328 656 2005 726 322 10602008 1323 658 1968 1422 706 2144 707 448 9482009 1448 708 2159 1554 773 2334 861 338 13112010 1395 665 2102 1476 726 2232 865 340 12982011 1480 741 2196 1572 797 2350 908 378 13442012 1498 804 2179 1583 865 2313 959 431 14042013 1514 776 2233 1631 839 2434 910 397 13512014 1514 771 2238 1618 824 2423 962 425 14212015 1503 766 2226 1614 849 2397 874 310 1336

Table 265Cancer of the Thyroid (Invasive)

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2015 048 045 050 048 046 048 048 035 0561975-1979 055 044 061 055 045 061 052 038 0621980 048 038 053 049 040 054 042 029 0511981 050 042 055 050 043 054 048 026 0621982 048 037 053 047 037 053 048 038 0541983 044 034 050 045 035 050 041 028 0491984 047 038 052 047 039 051 047 - 0641985 045 039 048 044 039 046 049 034 0581986 046 039 049 045 039 049 048 034 0571987 045 040 048 045 041 047 048 033 0581988 044 041 045 044 042 044 044 033 0501989 044 041 044 043 041 043 051 040 0561990 044 037 048 044 038 047 045 030 0541991 043 038 046 042 039 043 050 037 0581992 046 038 050 046 039 048 041 030 0481993 046 039 050 046 040 048 046 026 0581994 042 038 044 042 038 044 037 030 0401995 044 041 044 044 043 044 040 027 0461996 045 042 047 045 043 046 044 033 0491997 046 045 046 045 045 044 049 037 0551998 044 038 047 043 039 045 043 027 0531999 045 044 045 045 045 044 044 039 0472000 048 047 048 047 048 045 051 034 0592001 048 047 048 047 048 046 051 041 0582002 048 045 048 048 046 048 048 039 0522003 045 043 046 046 045 046 038 029 0442004 048 047 047 048 048 047 045 040 0482005 048 048 049 048 050 046 051 030 0642006 049 046 051 050 048 050 047 028 0602007 050 051 048 048 051 046 050 040 0562008 052 050 052 052 052 051 046 040 0512009 052 051 052 051 052 050 057 041 0662010 051 050 051 050 051 048 049 045 0532011 051 052 049 051 054 048 044 032 0512012 048 051 046 048 052 045 049 041 0542013 052 053 050 051 054 048 052 039 0612014 050 049 050 050 052 048 056 038 0662015 051 054 048 050 055 046 049 041 053

Table 266Cancer of the Thyroid (Invasive)

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a SEER 18 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2011-2015All ages 145 73 214 153 78 228 89 38 134Under 65 132 58 205 141 63 220 76 27 12065 and over 231 175 278 235 182 282 181 114 228

All ages (WHO world std)c 128 62 192 135 66 205 76 31 116

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 02 - 02 02 - 03 - - -10-14 09 05 14 11 05 16 - - -15-19 31 09 53 34 10 60 11 - 1820-24 62 20 107 71 23 124 17 - 3225-29 105 35 179 117 40 200 42 11 7230-34 160 57 264 175 63 291 67 16 11335-39 201 74 328 214 78 354 111 32 18240-44 220 91 347 230 97 367 146 48 23345-49 236 109 362 249 117 382 144 47 23150-54 256 123 385 270 133 407 152 59 23455-59 262 144 373 275 154 393 172 89 24360-64 260 163 348 267 174 355 203 91 29565-69 290 199 370 294 207 373 225 127 30070-74 259 195 313 268 204 323 195 131 24175-79 231 177 272 237 184 280 179 118 22080-84 174 157 186 175 161 186 129 106 14185+ 110 96 117 107 99 111 122 - 153

US MortalityAge at DeathAge-Adjusted Rates 2011-2015All ages 05 05 05 05 05 05 05 04 06Under 65 01 02 01 01 02 01 02 01 0265 and over 30 30 29 29 30 28 29 21 33

All ages (WHO world std)c 03 04 03 03 04 03 03 03 04

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 00 - - 00 - - - - -30-34 00 00 - 00 - - - - -35-39 00 00 00 00 00 - - - -40-44 01 01 01 01 01 01 - - -45-49 02 03 02 02 03 01 03 03 0350-54 04 04 03 04 05 03 04 03 0555-59 06 07 06 06 07 05 05 04 0660-64 11 12 10 11 12 09 12 09 1465-69 16 17 15 16 17 14 16 14 1870-74 22 22 21 21 22 21 25 20 2875-79 31 32 31 31 33 30 30 28 3180-84 43 42 43 42 43 41 37 23 4585+ 57 54 59 57 56 57 54 26 66

Table 267Cancer of the Thyroid (Invasive)

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2015 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2015

d Period survival provides a 2014 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2008-2014 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 83 75 87 - - -1970-1973a - - - 86 82 87 - - -1975-1977b 921 911 925 918 907 922 898 - 9101978-1980b 921 872 936 915 875 927 902 680h 9551981-1983b 936 922 939 931 909 937 964 1000 9321984-1986b 932 898 943 932 894 944 893 855g 9031987-1989b 944 916 952 941 916 950 923 912g 9231990-1992b 943 905 955 949 916 960 859 845g 8631993-1995b 954 916 967 956 915 969 932 878g 9431996-1998b 956 910 969 959 913 973 951 865g 9661999-2001b 965 943 971 968 949 974 920 884g 9242002-2004b 973 939 982 974 941 983 959 942 9602005-2007b 979 961 985 980 961 986 963 915 9692008-2014b 983f 960f 989f 986f 965f 992f 970f 913 979f

5-Year Period Survival (Percent)cd

2014 982 958 989 984 961 990 969 928 974

Stage Distribution () 2008-2014ce

All StagesNumber of cases 74280 17072 57208 59623 14147 45476 5139 909 4230Percent 100 100 100 100 100 100 100 100 100Localized 67 58 70 67 58 70 80 72 81Regional 27 33 25 27 34 25 14 18 13Distant 4 7 3 4 6 3 4 8 4UnstagedUnknown 2 2 2 2 2 2 2 2 2

5-Year Relative Survival (Percent) 2008-2014c

Age at DiagnosisAges lt45 997 991 998 997 993 998 992 965 995Ages 45-54 988 962 995 988 964 995 990 959 995Ages 55-64 980 952 989 983 953 992 956 920 963Ages 65-74 963 917 974 966 923 977 939 822g 965Ages 75+ 863 847 867 884 863 888 754 728g 739Ages lt65 991 971 996 991 972 996 983 952 990Ages 65+ 932 896 943 942 905 949 889 824g 903

StageeAll Stages 981 956 988 983 958 990 972 929 977Localized 999 998 1000 999 998 1000 998 989 999Regional 980 964 987 982 966 989 944 896 958Distant 555 509 583 558 507 592 470 424g 487UnstagedUnknown 891 836 909 884 845 897 887 - 915

Table 268Cancer of the Thyroid (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 949 951 959 962 967 968 964 977 972 976 976 971 979 983 977 985 985 983 988 989 987 988 983 9872-year 935 945 952 957 961 966 962 971 971 970 974 971 979 979 973 984 981 982 987 986 986 984 9823-year 929 937 948 953 960 960 962 969 971 969 970 971 977 979 973 983 980 982 987 985 986 9844-year 925 934 943 950 959 954 956 963 970 969 970 971 974 977 973 983 979 980 987 984 9865-year 921 933 941 947 958 949 953 962 969 963 962 971 973 973 973 982 979 978 987 9816-year 916 931 938 943 958 948 952 958 964 963 962 967 970 972 973 982 979 978 9877-year 914 927 934 942 956 945 952 958 962 961 961 965 968 969 973 981 979 9788-year 911 926 933 941 955 942 951 958 960 959 959 963 967 968 973 980 9799-year 907 923 931 939 955 937 949 958 956 959 954 963 967 968 973 98010-year 905 920 928 936 951 936 949 958 954 958 954 963 967 967 97311-year 903 917 927 933 950 933 949 958 950 958 954 961 967 96512-year 903 914 926 930 950 930 949 958 948 958 954 959 96713-year 900 912 925 930 950 928 949 950 947 958 954 95914-year 899 912 924 927 950 926 949 946 946 958 95415-year 897 907 923 923 943 924 949 941 945 95816-year 896 906 923 922 938 924 949 938 94517-year 895 906 922 922 938 923 949 93718-year 893 905 922 921 938 923 94319-year 892 905 919 921 938 92320-year 892 905 919 921 938

Table 269Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 946 925 948 946 934 937 918 972 965 963 961 951 956 967 971 964 973 968 983 978 973 979 967 9712-year 925 920 937 932 919 934 909 954 962 949 955 949 953 951 956 961 965 961 982 963 969 972 9643-year 915 908 935 924 917 921 909 947 962 949 942 949 942 948 956 961 965 961 982 961 967 9684-year 905 904 921 919 914 917 895 937 962 949 936 946 935 943 956 961 965 957 982 956 9675-year 899 902 916 910 912 898 882 937 962 938 924 943 932 940 956 957 963 951 980 9436-year 896 898 911 906 903 898 880 935 958 938 920 938 917 940 956 957 963 951 9787-year 894 893 900 904 887 895 880 933 954 934 919 924 917 928 956 953 963 9498-year 893 893 896 901 887 885 878 933 952 934 911 915 917 925 953 953 9639-year 888 886 885 899 887 867 869 933 930 934 898 910 917 921 953 95310-year 883 879 885 897 874 864 869 933 926 934 896 910 917 915 94911-year 875 872 884 895 862 848 865 933 926 934 896 902 917 91512-year 875 864 883 887 860 841 865 931 926 934 893 899 91713-year 873 862 878 882 860 831 865 931 926 927 893 89914-year 873 862 877 878 858 827 865 931 926 927 89315-year 867 854 877 872 858 827 865 931 926 92416-year 866 853 877 868 858 827 865 923 92617-year 866 849 877 868 858 827 865 91818-year 866 846 877 865 858 827 86019-year 866 846 877 864 858 82220-year 866 846 877 864 858

Table 2610Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 950 960 963 968 978 977 977 979 974 980 980 977 986 988 979 990 989 987 989 991 991 991 988 9912-year 939 953 957 966 974 975 977 976 974 977 980 977 985 987 979 990 985 987 988 991 991 988 9873-year 933 947 952 963 973 971 977 975 974 975 977 977 985 987 979 989 985 987 988 991 991 9884-year 931 944 950 961 973 965 975 971 972 975 977 977 985 987 979 989 983 986 987 991 9905-year 927 943 949 959 972 964 974 969 969 970 973 977 984 983 979 989 983 986 987 9906-year 923 942 947 955 972 961 973 965 965 970 973 976 983 981 979 989 983 986 9877-year 921 938 945 954 972 959 973 965 963 970 973 976 981 980 979 989 983 9858-year 917 937 945 954 972 959 973 965 962 966 973 976 980 980 979 987 9839-year 913 936 945 953 972 958 973 965 962 966 970 976 979 980 979 98710-year 912 934 942 949 972 957 973 965 960 964 970 976 977 980 97911-year 912 932 940 946 972 957 973 965 958 964 970 976 977 97912-year 911 931 940 945 972 955 973 965 952 964 970 976 97713-year 909 929 940 944 972 955 973 955 949 964 970 97614-year 908 928 939 943 972 955 973 949 946 964 97015-year 907 924 938 940 967 950 973 943 944 96416-year 906 923 937 939 958 950 973 942 94417-year 904 923 936 939 958 950 971 94118-year 899 923 935 938 958 950 96719-year 898 923 932 938 958 95020-year 898 923 932 938 958

Table 2611Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 002 011 122 006 Asian 0 000 002 010 128 011

10 002 011 029 123 006 Pacific 10 002 010 027 129 011

20 009 027 049 121 006 Islander 20 008 024 047 127 011

30 018 040 065 114 007 30 017 039 063 120 011

40 023 047 072 097 007 40 022 046 072 104 011

50 025 050 068 077 007 50 024 051 070 083 011

60 026 046 053 054 006 60 027 047 058 060 011

70 022 030 - 032 006 70 021 032 - 035 010

80 011 - - 013 005 80 013 - - 017 008

White 0 000 003 012 128 006 American 0 000 002 007 083 007

10 003 012 031 129 006 Indian 10 002 007 018 084 007

20 010 029 052 127 006 Alaska 20 005 016 026 083 007

30 019 043 069 118 006 Nativea 30 011 021 036 079 007

40 024 050 074 100 006 40 010 026 043 070 007

50 027 052 071 079 006 50 016 034 048 063 008

60 027 047 054 055 006 60 019 034 047 050 007

70 022 031 - 032 006 70 017 032 - 035 007

80 011 - - 013 005 80 020 - - 024 009

Black 0 000 001 004 074 006 Hispanicb 0 000 002 009 114 009

10 001 004 012 076 006 10 002 009 023 115 009

20 003 012 026 075 006 20 007 021 040 113 009

30 009 023 038 073 006 30 014 033 055 107 009

40 015 030 048 066 006 40 019 042 065 094 010

50 016 034 046 053 006 50 023 047 067 077 010

60 020 033 039 040 006 60 025 045 053 056 009

70 016 023 - 025 006 70 022 031 - 034 009

80 010 - - 013 005 80 011 - - 014 007

Table 2612

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 001 004 064 006 Asian 0 000 001 004 067 008

10 001 004 010 065 006 Pacific 10 001 004 010 067 008

20 003 009 019 064 006 Islander 20 003 009 020 066 008

30 007 016 029 062 006 30 007 017 028 064 008

40 010 022 038 056 006 40 010 021 036 058 008

50 013 029 042 048 006 50 011 026 039 048 008

60 017 031 037 038 006 60 016 029 038 038 008

70 016 023 - 024 005 70 015 024 - 025 007

80 010 - - 011 004 80 011 - - 012 006

White 0 000 001 004 068 006 American 0 000 001 003 034 006

10 001 004 011 069 006 Indian 10 001 003 006 035 006

20 003 010 020 068 006 Alaska 20 002 005 008 034 006

30 007 017 031 066 006 Nativea 30 003 006 010 033 006

40 010 024 040 060 006 40 002 007 015 030 006

50 014 031 045 051 006 50 005 013 022 030 007

60 018 033 039 039 006 60 009 019 027 027 007

70 017 024 - 025 005 70 011 020 - 021 007

80 010 - - 011 004 80 013 - - 014 008

Black 0 000 000 001 031 003 Hispanicb 0 000 001 003 050 007

10 000 001 004 031 004 10 001 003 007 050 007

20 001 003 008 031 004 20 002 006 012 050 007

30 003 007 014 031 004 30 004 011 020 048 007

40 004 012 020 029 004 40 006 016 028 045 007

50 008 016 023 026 004 50 010 022 033 039 007

60 010 017 021 021 004 60 013 025 030 031 007

70 010 014 - 014 003 70 013 019 - 020 006

80 007 - - 007 002 80 008 - - 010 005

Table 2613

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 004 019 181 007 Asian 0 000 003 016 183 013

10 004 018 048 182 007 Pacific 10 003 016 042 184 013

20 015 044 079 179 007 Islander 20 013 039 072 181 013

30 030 065 101 165 007 30 026 059 094 169 013

40 036 072 105 137 007 40 033 068 104 144 013

50 037 071 094 104 007 50 035 071 096 112 013

60 035 059 068 070 007 60 037 062 074 079 013

70 027 036 - 038 006 70 027 039 - 044 012

80 012 - - 015 005 80 015 - - 020 009

White 0 000 004 021 190 007 American 0 000 003 011 132 008

10 004 021 053 192 007 Indian 10 002 011 030 133 008

20 017 049 086 188 007 Alaska 20 009 027 044 131 008

30 032 070 108 172 007 Nativea 30 019 036 062 124 008

40 038 076 109 141 007 40 017 044 069 107 008

50 039 073 097 106 007 50 027 054 073 093 008

60 035 060 069 070 007 60 028 048 065 069 007

70 027 037 - 038 006 70 022 041 - 046 007

80 012 - - 014 005 80 024 - - 030 008

Black 0 000 001 007 114 008 Hispanicb 0 000 004 017 179 011

10 001 007 021 116 008 10 004 017 041 180 011

20 006 020 043 116 008 20 013 038 069 177 011

30 015 038 061 111 008 30 025 056 092 165 011

40 024 047 072 098 008 40 031 068 102 141 011

50 024 050 067 076 008 50 037 072 098 111 011

60 028 046 054 056 008 60 036 063 074 077 011

70 021 030 - 033 008 70 030 041 - 044 010

80 012 - - 016 006 80 014 - - 017 008

Table 2614

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 3: SEER Cancer Statistics Review 1975-2015

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Regression Program Version 46 February 2018 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 13 areas (SEER 9 Areas Los Angeles San Jose-Monterey Rural Georgia and the Alaska Native Registry)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native RegistryThe Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

g Data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15

SEER 9 Delay-Adjusted Incidencea 1975-2015All Races 1975-77 65 1977-80 -52 1980-93 23 1993-99 44 1999-09 71 2009-15 12 31 12White 1975-81 -11 1981-93 24 1993-99 51 1999-09 74 2009-15 11 32 11Black 1975-89 -11 1989-15 55 55 55

SEER 13 Delay-Adjusted Incidenceb 1992-2015All Races 1992-99 41 1999-09 69 2009-15 14 32 14White 1992-98 44 1998-09 70 2009-15 14 32 14Black 1992-98 29 1998-11 75 2011-15 -06 38 -06

SEER 9 Observed Incidencea 1975-2015All Races 1975-77 65 1977-80 -52 1980-93 23 1993-99 45 1999-09 71 2009-15 10 30 10White 1975-81 -11 1981-93 24 1993-99 52 1999-09 74 2009-15 09 30 09Black 1975-93 02 1993-12 63 2012-15 -14 37 05

SEER 13 Observed Incidenceb 1992-2015All Races 1992-99 41 1999-09 69 2009-15 12 31 12White 1992-98 44 1998-09 70 2009-15 12 31 12White NHef 1992-99 56 1999-09 73 2009-15 08 29 08

Black 1992-98 30 1998-11 74 2011-15 -11 35 -11Black NHef 1992-98 28 1998-11 76 2011-15 -11 36 -11

APIe 1992-99 03 1999-10 53 2010-15 00 23 00AIANeg 1992-15 40 40 40Hispanicf 1992-95 -42 1995-13 51 2013-15 -13 37 19

US Cancer Mortalityc 1975-2015All Races 1975-88 -25 1988-15 03 03 03White 1975-88 -28 1988-15 03 03 03Black 1975-15 00 00 00

US Cancer Mortalityc 1992-2015All Races 1992-94 -49 1994-15 05 05 05White 1992-15 02 02 02White NHef 1992-15 02 02 02

Black 1992-15 08 08 08Black NHef 1992-15 09 09 09

APIe 1992-15 -10 -10 -10AIANeg 1992-15 -12 -12 -12Hispanicf 1992-15 -05 -05 -05

Table 263Cancer of the Thyroid (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program1975-2015 With up to Five Joinpoints 1992-2015 With up to Four Joinpoints

Females by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-1979 493 307 669 482 293 662 327 164 4631980 433 239 615 429 228 620 237 111 3431981 442 252 624 439 248 628 239 104 3441982 463 300 615 453 287 609 329 202 4341983 471 280 650 474 261 673 302 215 3771984 485 265 693 473 258 681 302 173 4081985 513 310 709 509 310 704 286 189 3661986 533 307 750 525 310 737 335 119 5091987 504 281 712 502 286 706 282 097 4301988 493 294 688 489 300 678 253 180 3211989 537 299 766 547 322 770 263 062 4141990 549 293 795 555 299 807 376 228 4911991 549 319 769 570 331 804 322 207 4201992 588 352 813 588 352 817 423 309 5181993 565 359 764 574 368 777 338 207 4561994 609 339 875 624 344 903 375 178 5351995 623 337 902 642 359 923 308 120 4611996 652 347 951 672 361 983 389 179 5801997 678 366 980 706 377 1034 398 244 5241998 699 372 1012 720 395 1041 403 150 6111999 735 387 1068 756 408 1098 459 160 7012000 762 404 1110 805 438 1177 457 218 6552001 831 434 1218 868 462 1278 493 252 6882002 924 495 1343 976 527 1429 552 285 7682003 966 472 1448 1038 506 1571 530 282 7512004 1015 524 1494 1082 555 1613 637 333 8902005 1098 581 1599 1195 648 1743 592 276 8682006 1133 586 1663 1217 637 1800 664 315 9472007 1243 613 1854 1329 657 2007 728 323 10622008 1325 659 1972 1425 707 2148 710 450 9532009 1451 710 2165 1559 775 2341 867 340 13202010 1400 667 2110 1482 729 2241 873 344 13112011 1486 744 2205 1580 801 2362 919 382 13602012 1506 808 2190 1592 870 2327 973 437 14252013 1524 781 2249 1645 846 2454 924 403 13712014 1526 777 2257 1635 833 2449 984 436 14532015 1522 776 2254 1643 864 2439 899 319 1374

Table 264Cancer of the Thyroid (Invasive)

Delay-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2015 870 466 1259 890 484 1293 550 259 7931975-1979 493 307 669 482 293 662 327 164 4631980 433 239 615 429 228 620 237 - 3431981 442 252 624 439 248 628 239 - 3441982 463 300 615 453 287 609 329 - 4341983 471 280 650 474 261 673 302 215 3771984 485 265 693 473 258 681 302 - 4081985 513 310 709 509 310 704 286 - 3661986 533 307 750 525 310 737 335 - 5091987 504 281 712 502 286 706 282 - 4301988 493 294 688 489 300 678 253 - 3211989 537 299 766 547 322 770 263 - 4141990 549 293 795 555 299 807 376 228 4911991 549 319 769 570 331 804 322 207 4201992 588 352 813 588 352 817 423 309 5181993 565 359 764 574 368 777 338 207 4561994 609 339 875 624 344 903 375 178 5351995 623 337 902 642 359 923 308 - 4611996 652 347 951 672 361 983 389 179 5801997 678 366 980 706 377 1034 398 244 5241998 699 372 1012 720 395 1041 403 150 6111999 735 387 1068 756 408 1098 459 160 7012000 762 404 1110 805 438 1177 457 218 6552001 831 434 1218 868 462 1278 493 252 6882002 924 495 1343 976 527 1429 552 285 7682003 966 472 1448 1038 506 1571 530 282 7512004 1015 524 1494 1082 555 1613 637 333 8902005 1098 581 1599 1195 648 1743 592 276 8682006 1133 586 1663 1217 637 1800 664 315 9472007 1241 612 1853 1328 656 2005 726 322 10602008 1323 658 1968 1422 706 2144 707 448 9482009 1448 708 2159 1554 773 2334 861 338 13112010 1395 665 2102 1476 726 2232 865 340 12982011 1480 741 2196 1572 797 2350 908 378 13442012 1498 804 2179 1583 865 2313 959 431 14042013 1514 776 2233 1631 839 2434 910 397 13512014 1514 771 2238 1618 824 2423 962 425 14212015 1503 766 2226 1614 849 2397 874 310 1336

Table 265Cancer of the Thyroid (Invasive)

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2015 048 045 050 048 046 048 048 035 0561975-1979 055 044 061 055 045 061 052 038 0621980 048 038 053 049 040 054 042 029 0511981 050 042 055 050 043 054 048 026 0621982 048 037 053 047 037 053 048 038 0541983 044 034 050 045 035 050 041 028 0491984 047 038 052 047 039 051 047 - 0641985 045 039 048 044 039 046 049 034 0581986 046 039 049 045 039 049 048 034 0571987 045 040 048 045 041 047 048 033 0581988 044 041 045 044 042 044 044 033 0501989 044 041 044 043 041 043 051 040 0561990 044 037 048 044 038 047 045 030 0541991 043 038 046 042 039 043 050 037 0581992 046 038 050 046 039 048 041 030 0481993 046 039 050 046 040 048 046 026 0581994 042 038 044 042 038 044 037 030 0401995 044 041 044 044 043 044 040 027 0461996 045 042 047 045 043 046 044 033 0491997 046 045 046 045 045 044 049 037 0551998 044 038 047 043 039 045 043 027 0531999 045 044 045 045 045 044 044 039 0472000 048 047 048 047 048 045 051 034 0592001 048 047 048 047 048 046 051 041 0582002 048 045 048 048 046 048 048 039 0522003 045 043 046 046 045 046 038 029 0442004 048 047 047 048 048 047 045 040 0482005 048 048 049 048 050 046 051 030 0642006 049 046 051 050 048 050 047 028 0602007 050 051 048 048 051 046 050 040 0562008 052 050 052 052 052 051 046 040 0512009 052 051 052 051 052 050 057 041 0662010 051 050 051 050 051 048 049 045 0532011 051 052 049 051 054 048 044 032 0512012 048 051 046 048 052 045 049 041 0542013 052 053 050 051 054 048 052 039 0612014 050 049 050 050 052 048 056 038 0662015 051 054 048 050 055 046 049 041 053

Table 266Cancer of the Thyroid (Invasive)

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a SEER 18 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2011-2015All ages 145 73 214 153 78 228 89 38 134Under 65 132 58 205 141 63 220 76 27 12065 and over 231 175 278 235 182 282 181 114 228

All ages (WHO world std)c 128 62 192 135 66 205 76 31 116

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 02 - 02 02 - 03 - - -10-14 09 05 14 11 05 16 - - -15-19 31 09 53 34 10 60 11 - 1820-24 62 20 107 71 23 124 17 - 3225-29 105 35 179 117 40 200 42 11 7230-34 160 57 264 175 63 291 67 16 11335-39 201 74 328 214 78 354 111 32 18240-44 220 91 347 230 97 367 146 48 23345-49 236 109 362 249 117 382 144 47 23150-54 256 123 385 270 133 407 152 59 23455-59 262 144 373 275 154 393 172 89 24360-64 260 163 348 267 174 355 203 91 29565-69 290 199 370 294 207 373 225 127 30070-74 259 195 313 268 204 323 195 131 24175-79 231 177 272 237 184 280 179 118 22080-84 174 157 186 175 161 186 129 106 14185+ 110 96 117 107 99 111 122 - 153

US MortalityAge at DeathAge-Adjusted Rates 2011-2015All ages 05 05 05 05 05 05 05 04 06Under 65 01 02 01 01 02 01 02 01 0265 and over 30 30 29 29 30 28 29 21 33

All ages (WHO world std)c 03 04 03 03 04 03 03 03 04

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 00 - - 00 - - - - -30-34 00 00 - 00 - - - - -35-39 00 00 00 00 00 - - - -40-44 01 01 01 01 01 01 - - -45-49 02 03 02 02 03 01 03 03 0350-54 04 04 03 04 05 03 04 03 0555-59 06 07 06 06 07 05 05 04 0660-64 11 12 10 11 12 09 12 09 1465-69 16 17 15 16 17 14 16 14 1870-74 22 22 21 21 22 21 25 20 2875-79 31 32 31 31 33 30 30 28 3180-84 43 42 43 42 43 41 37 23 4585+ 57 54 59 57 56 57 54 26 66

Table 267Cancer of the Thyroid (Invasive)

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2015 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2015

d Period survival provides a 2014 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2008-2014 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 83 75 87 - - -1970-1973a - - - 86 82 87 - - -1975-1977b 921 911 925 918 907 922 898 - 9101978-1980b 921 872 936 915 875 927 902 680h 9551981-1983b 936 922 939 931 909 937 964 1000 9321984-1986b 932 898 943 932 894 944 893 855g 9031987-1989b 944 916 952 941 916 950 923 912g 9231990-1992b 943 905 955 949 916 960 859 845g 8631993-1995b 954 916 967 956 915 969 932 878g 9431996-1998b 956 910 969 959 913 973 951 865g 9661999-2001b 965 943 971 968 949 974 920 884g 9242002-2004b 973 939 982 974 941 983 959 942 9602005-2007b 979 961 985 980 961 986 963 915 9692008-2014b 983f 960f 989f 986f 965f 992f 970f 913 979f

5-Year Period Survival (Percent)cd

2014 982 958 989 984 961 990 969 928 974

Stage Distribution () 2008-2014ce

All StagesNumber of cases 74280 17072 57208 59623 14147 45476 5139 909 4230Percent 100 100 100 100 100 100 100 100 100Localized 67 58 70 67 58 70 80 72 81Regional 27 33 25 27 34 25 14 18 13Distant 4 7 3 4 6 3 4 8 4UnstagedUnknown 2 2 2 2 2 2 2 2 2

5-Year Relative Survival (Percent) 2008-2014c

Age at DiagnosisAges lt45 997 991 998 997 993 998 992 965 995Ages 45-54 988 962 995 988 964 995 990 959 995Ages 55-64 980 952 989 983 953 992 956 920 963Ages 65-74 963 917 974 966 923 977 939 822g 965Ages 75+ 863 847 867 884 863 888 754 728g 739Ages lt65 991 971 996 991 972 996 983 952 990Ages 65+ 932 896 943 942 905 949 889 824g 903

StageeAll Stages 981 956 988 983 958 990 972 929 977Localized 999 998 1000 999 998 1000 998 989 999Regional 980 964 987 982 966 989 944 896 958Distant 555 509 583 558 507 592 470 424g 487UnstagedUnknown 891 836 909 884 845 897 887 - 915

Table 268Cancer of the Thyroid (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 949 951 959 962 967 968 964 977 972 976 976 971 979 983 977 985 985 983 988 989 987 988 983 9872-year 935 945 952 957 961 966 962 971 971 970 974 971 979 979 973 984 981 982 987 986 986 984 9823-year 929 937 948 953 960 960 962 969 971 969 970 971 977 979 973 983 980 982 987 985 986 9844-year 925 934 943 950 959 954 956 963 970 969 970 971 974 977 973 983 979 980 987 984 9865-year 921 933 941 947 958 949 953 962 969 963 962 971 973 973 973 982 979 978 987 9816-year 916 931 938 943 958 948 952 958 964 963 962 967 970 972 973 982 979 978 9877-year 914 927 934 942 956 945 952 958 962 961 961 965 968 969 973 981 979 9788-year 911 926 933 941 955 942 951 958 960 959 959 963 967 968 973 980 9799-year 907 923 931 939 955 937 949 958 956 959 954 963 967 968 973 98010-year 905 920 928 936 951 936 949 958 954 958 954 963 967 967 97311-year 903 917 927 933 950 933 949 958 950 958 954 961 967 96512-year 903 914 926 930 950 930 949 958 948 958 954 959 96713-year 900 912 925 930 950 928 949 950 947 958 954 95914-year 899 912 924 927 950 926 949 946 946 958 95415-year 897 907 923 923 943 924 949 941 945 95816-year 896 906 923 922 938 924 949 938 94517-year 895 906 922 922 938 923 949 93718-year 893 905 922 921 938 923 94319-year 892 905 919 921 938 92320-year 892 905 919 921 938

Table 269Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 946 925 948 946 934 937 918 972 965 963 961 951 956 967 971 964 973 968 983 978 973 979 967 9712-year 925 920 937 932 919 934 909 954 962 949 955 949 953 951 956 961 965 961 982 963 969 972 9643-year 915 908 935 924 917 921 909 947 962 949 942 949 942 948 956 961 965 961 982 961 967 9684-year 905 904 921 919 914 917 895 937 962 949 936 946 935 943 956 961 965 957 982 956 9675-year 899 902 916 910 912 898 882 937 962 938 924 943 932 940 956 957 963 951 980 9436-year 896 898 911 906 903 898 880 935 958 938 920 938 917 940 956 957 963 951 9787-year 894 893 900 904 887 895 880 933 954 934 919 924 917 928 956 953 963 9498-year 893 893 896 901 887 885 878 933 952 934 911 915 917 925 953 953 9639-year 888 886 885 899 887 867 869 933 930 934 898 910 917 921 953 95310-year 883 879 885 897 874 864 869 933 926 934 896 910 917 915 94911-year 875 872 884 895 862 848 865 933 926 934 896 902 917 91512-year 875 864 883 887 860 841 865 931 926 934 893 899 91713-year 873 862 878 882 860 831 865 931 926 927 893 89914-year 873 862 877 878 858 827 865 931 926 927 89315-year 867 854 877 872 858 827 865 931 926 92416-year 866 853 877 868 858 827 865 923 92617-year 866 849 877 868 858 827 865 91818-year 866 846 877 865 858 827 86019-year 866 846 877 864 858 82220-year 866 846 877 864 858

Table 2610Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 950 960 963 968 978 977 977 979 974 980 980 977 986 988 979 990 989 987 989 991 991 991 988 9912-year 939 953 957 966 974 975 977 976 974 977 980 977 985 987 979 990 985 987 988 991 991 988 9873-year 933 947 952 963 973 971 977 975 974 975 977 977 985 987 979 989 985 987 988 991 991 9884-year 931 944 950 961 973 965 975 971 972 975 977 977 985 987 979 989 983 986 987 991 9905-year 927 943 949 959 972 964 974 969 969 970 973 977 984 983 979 989 983 986 987 9906-year 923 942 947 955 972 961 973 965 965 970 973 976 983 981 979 989 983 986 9877-year 921 938 945 954 972 959 973 965 963 970 973 976 981 980 979 989 983 9858-year 917 937 945 954 972 959 973 965 962 966 973 976 980 980 979 987 9839-year 913 936 945 953 972 958 973 965 962 966 970 976 979 980 979 98710-year 912 934 942 949 972 957 973 965 960 964 970 976 977 980 97911-year 912 932 940 946 972 957 973 965 958 964 970 976 977 97912-year 911 931 940 945 972 955 973 965 952 964 970 976 97713-year 909 929 940 944 972 955 973 955 949 964 970 97614-year 908 928 939 943 972 955 973 949 946 964 97015-year 907 924 938 940 967 950 973 943 944 96416-year 906 923 937 939 958 950 973 942 94417-year 904 923 936 939 958 950 971 94118-year 899 923 935 938 958 950 96719-year 898 923 932 938 958 95020-year 898 923 932 938 958

Table 2611Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 002 011 122 006 Asian 0 000 002 010 128 011

10 002 011 029 123 006 Pacific 10 002 010 027 129 011

20 009 027 049 121 006 Islander 20 008 024 047 127 011

30 018 040 065 114 007 30 017 039 063 120 011

40 023 047 072 097 007 40 022 046 072 104 011

50 025 050 068 077 007 50 024 051 070 083 011

60 026 046 053 054 006 60 027 047 058 060 011

70 022 030 - 032 006 70 021 032 - 035 010

80 011 - - 013 005 80 013 - - 017 008

White 0 000 003 012 128 006 American 0 000 002 007 083 007

10 003 012 031 129 006 Indian 10 002 007 018 084 007

20 010 029 052 127 006 Alaska 20 005 016 026 083 007

30 019 043 069 118 006 Nativea 30 011 021 036 079 007

40 024 050 074 100 006 40 010 026 043 070 007

50 027 052 071 079 006 50 016 034 048 063 008

60 027 047 054 055 006 60 019 034 047 050 007

70 022 031 - 032 006 70 017 032 - 035 007

80 011 - - 013 005 80 020 - - 024 009

Black 0 000 001 004 074 006 Hispanicb 0 000 002 009 114 009

10 001 004 012 076 006 10 002 009 023 115 009

20 003 012 026 075 006 20 007 021 040 113 009

30 009 023 038 073 006 30 014 033 055 107 009

40 015 030 048 066 006 40 019 042 065 094 010

50 016 034 046 053 006 50 023 047 067 077 010

60 020 033 039 040 006 60 025 045 053 056 009

70 016 023 - 025 006 70 022 031 - 034 009

80 010 - - 013 005 80 011 - - 014 007

Table 2612

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 001 004 064 006 Asian 0 000 001 004 067 008

10 001 004 010 065 006 Pacific 10 001 004 010 067 008

20 003 009 019 064 006 Islander 20 003 009 020 066 008

30 007 016 029 062 006 30 007 017 028 064 008

40 010 022 038 056 006 40 010 021 036 058 008

50 013 029 042 048 006 50 011 026 039 048 008

60 017 031 037 038 006 60 016 029 038 038 008

70 016 023 - 024 005 70 015 024 - 025 007

80 010 - - 011 004 80 011 - - 012 006

White 0 000 001 004 068 006 American 0 000 001 003 034 006

10 001 004 011 069 006 Indian 10 001 003 006 035 006

20 003 010 020 068 006 Alaska 20 002 005 008 034 006

30 007 017 031 066 006 Nativea 30 003 006 010 033 006

40 010 024 040 060 006 40 002 007 015 030 006

50 014 031 045 051 006 50 005 013 022 030 007

60 018 033 039 039 006 60 009 019 027 027 007

70 017 024 - 025 005 70 011 020 - 021 007

80 010 - - 011 004 80 013 - - 014 008

Black 0 000 000 001 031 003 Hispanicb 0 000 001 003 050 007

10 000 001 004 031 004 10 001 003 007 050 007

20 001 003 008 031 004 20 002 006 012 050 007

30 003 007 014 031 004 30 004 011 020 048 007

40 004 012 020 029 004 40 006 016 028 045 007

50 008 016 023 026 004 50 010 022 033 039 007

60 010 017 021 021 004 60 013 025 030 031 007

70 010 014 - 014 003 70 013 019 - 020 006

80 007 - - 007 002 80 008 - - 010 005

Table 2613

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 004 019 181 007 Asian 0 000 003 016 183 013

10 004 018 048 182 007 Pacific 10 003 016 042 184 013

20 015 044 079 179 007 Islander 20 013 039 072 181 013

30 030 065 101 165 007 30 026 059 094 169 013

40 036 072 105 137 007 40 033 068 104 144 013

50 037 071 094 104 007 50 035 071 096 112 013

60 035 059 068 070 007 60 037 062 074 079 013

70 027 036 - 038 006 70 027 039 - 044 012

80 012 - - 015 005 80 015 - - 020 009

White 0 000 004 021 190 007 American 0 000 003 011 132 008

10 004 021 053 192 007 Indian 10 002 011 030 133 008

20 017 049 086 188 007 Alaska 20 009 027 044 131 008

30 032 070 108 172 007 Nativea 30 019 036 062 124 008

40 038 076 109 141 007 40 017 044 069 107 008

50 039 073 097 106 007 50 027 054 073 093 008

60 035 060 069 070 007 60 028 048 065 069 007

70 027 037 - 038 006 70 022 041 - 046 007

80 012 - - 014 005 80 024 - - 030 008

Black 0 000 001 007 114 008 Hispanicb 0 000 004 017 179 011

10 001 007 021 116 008 10 004 017 041 180 011

20 006 020 043 116 008 20 013 038 069 177 011

30 015 038 061 111 008 30 025 056 092 165 011

40 024 047 072 098 008 40 031 068 102 141 011

50 024 050 067 076 008 50 037 072 098 111 011

60 028 046 054 056 008 60 036 063 074 077 011

70 021 030 - 033 008 70 030 041 - 044 010

80 012 - - 016 006 80 014 - - 017 008

Table 2614

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

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1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

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ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

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1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

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1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 4: SEER Cancer Statistics Review 1975-2015

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-1979 493 307 669 482 293 662 327 164 4631980 433 239 615 429 228 620 237 111 3431981 442 252 624 439 248 628 239 104 3441982 463 300 615 453 287 609 329 202 4341983 471 280 650 474 261 673 302 215 3771984 485 265 693 473 258 681 302 173 4081985 513 310 709 509 310 704 286 189 3661986 533 307 750 525 310 737 335 119 5091987 504 281 712 502 286 706 282 097 4301988 493 294 688 489 300 678 253 180 3211989 537 299 766 547 322 770 263 062 4141990 549 293 795 555 299 807 376 228 4911991 549 319 769 570 331 804 322 207 4201992 588 352 813 588 352 817 423 309 5181993 565 359 764 574 368 777 338 207 4561994 609 339 875 624 344 903 375 178 5351995 623 337 902 642 359 923 308 120 4611996 652 347 951 672 361 983 389 179 5801997 678 366 980 706 377 1034 398 244 5241998 699 372 1012 720 395 1041 403 150 6111999 735 387 1068 756 408 1098 459 160 7012000 762 404 1110 805 438 1177 457 218 6552001 831 434 1218 868 462 1278 493 252 6882002 924 495 1343 976 527 1429 552 285 7682003 966 472 1448 1038 506 1571 530 282 7512004 1015 524 1494 1082 555 1613 637 333 8902005 1098 581 1599 1195 648 1743 592 276 8682006 1133 586 1663 1217 637 1800 664 315 9472007 1243 613 1854 1329 657 2007 728 323 10622008 1325 659 1972 1425 707 2148 710 450 9532009 1451 710 2165 1559 775 2341 867 340 13202010 1400 667 2110 1482 729 2241 873 344 13112011 1486 744 2205 1580 801 2362 919 382 13602012 1506 808 2190 1592 870 2327 973 437 14252013 1524 781 2249 1645 846 2454 924 403 13712014 1526 777 2257 1635 833 2449 984 436 14532015 1522 776 2254 1643 864 2439 899 319 1374

Table 264Cancer of the Thyroid (Invasive)

Delay-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2015 870 466 1259 890 484 1293 550 259 7931975-1979 493 307 669 482 293 662 327 164 4631980 433 239 615 429 228 620 237 - 3431981 442 252 624 439 248 628 239 - 3441982 463 300 615 453 287 609 329 - 4341983 471 280 650 474 261 673 302 215 3771984 485 265 693 473 258 681 302 - 4081985 513 310 709 509 310 704 286 - 3661986 533 307 750 525 310 737 335 - 5091987 504 281 712 502 286 706 282 - 4301988 493 294 688 489 300 678 253 - 3211989 537 299 766 547 322 770 263 - 4141990 549 293 795 555 299 807 376 228 4911991 549 319 769 570 331 804 322 207 4201992 588 352 813 588 352 817 423 309 5181993 565 359 764 574 368 777 338 207 4561994 609 339 875 624 344 903 375 178 5351995 623 337 902 642 359 923 308 - 4611996 652 347 951 672 361 983 389 179 5801997 678 366 980 706 377 1034 398 244 5241998 699 372 1012 720 395 1041 403 150 6111999 735 387 1068 756 408 1098 459 160 7012000 762 404 1110 805 438 1177 457 218 6552001 831 434 1218 868 462 1278 493 252 6882002 924 495 1343 976 527 1429 552 285 7682003 966 472 1448 1038 506 1571 530 282 7512004 1015 524 1494 1082 555 1613 637 333 8902005 1098 581 1599 1195 648 1743 592 276 8682006 1133 586 1663 1217 637 1800 664 315 9472007 1241 612 1853 1328 656 2005 726 322 10602008 1323 658 1968 1422 706 2144 707 448 9482009 1448 708 2159 1554 773 2334 861 338 13112010 1395 665 2102 1476 726 2232 865 340 12982011 1480 741 2196 1572 797 2350 908 378 13442012 1498 804 2179 1583 865 2313 959 431 14042013 1514 776 2233 1631 839 2434 910 397 13512014 1514 771 2238 1618 824 2423 962 425 14212015 1503 766 2226 1614 849 2397 874 310 1336

Table 265Cancer of the Thyroid (Invasive)

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2015 048 045 050 048 046 048 048 035 0561975-1979 055 044 061 055 045 061 052 038 0621980 048 038 053 049 040 054 042 029 0511981 050 042 055 050 043 054 048 026 0621982 048 037 053 047 037 053 048 038 0541983 044 034 050 045 035 050 041 028 0491984 047 038 052 047 039 051 047 - 0641985 045 039 048 044 039 046 049 034 0581986 046 039 049 045 039 049 048 034 0571987 045 040 048 045 041 047 048 033 0581988 044 041 045 044 042 044 044 033 0501989 044 041 044 043 041 043 051 040 0561990 044 037 048 044 038 047 045 030 0541991 043 038 046 042 039 043 050 037 0581992 046 038 050 046 039 048 041 030 0481993 046 039 050 046 040 048 046 026 0581994 042 038 044 042 038 044 037 030 0401995 044 041 044 044 043 044 040 027 0461996 045 042 047 045 043 046 044 033 0491997 046 045 046 045 045 044 049 037 0551998 044 038 047 043 039 045 043 027 0531999 045 044 045 045 045 044 044 039 0472000 048 047 048 047 048 045 051 034 0592001 048 047 048 047 048 046 051 041 0582002 048 045 048 048 046 048 048 039 0522003 045 043 046 046 045 046 038 029 0442004 048 047 047 048 048 047 045 040 0482005 048 048 049 048 050 046 051 030 0642006 049 046 051 050 048 050 047 028 0602007 050 051 048 048 051 046 050 040 0562008 052 050 052 052 052 051 046 040 0512009 052 051 052 051 052 050 057 041 0662010 051 050 051 050 051 048 049 045 0532011 051 052 049 051 054 048 044 032 0512012 048 051 046 048 052 045 049 041 0542013 052 053 050 051 054 048 052 039 0612014 050 049 050 050 052 048 056 038 0662015 051 054 048 050 055 046 049 041 053

Table 266Cancer of the Thyroid (Invasive)

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a SEER 18 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2011-2015All ages 145 73 214 153 78 228 89 38 134Under 65 132 58 205 141 63 220 76 27 12065 and over 231 175 278 235 182 282 181 114 228

All ages (WHO world std)c 128 62 192 135 66 205 76 31 116

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 02 - 02 02 - 03 - - -10-14 09 05 14 11 05 16 - - -15-19 31 09 53 34 10 60 11 - 1820-24 62 20 107 71 23 124 17 - 3225-29 105 35 179 117 40 200 42 11 7230-34 160 57 264 175 63 291 67 16 11335-39 201 74 328 214 78 354 111 32 18240-44 220 91 347 230 97 367 146 48 23345-49 236 109 362 249 117 382 144 47 23150-54 256 123 385 270 133 407 152 59 23455-59 262 144 373 275 154 393 172 89 24360-64 260 163 348 267 174 355 203 91 29565-69 290 199 370 294 207 373 225 127 30070-74 259 195 313 268 204 323 195 131 24175-79 231 177 272 237 184 280 179 118 22080-84 174 157 186 175 161 186 129 106 14185+ 110 96 117 107 99 111 122 - 153

US MortalityAge at DeathAge-Adjusted Rates 2011-2015All ages 05 05 05 05 05 05 05 04 06Under 65 01 02 01 01 02 01 02 01 0265 and over 30 30 29 29 30 28 29 21 33

All ages (WHO world std)c 03 04 03 03 04 03 03 03 04

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 00 - - 00 - - - - -30-34 00 00 - 00 - - - - -35-39 00 00 00 00 00 - - - -40-44 01 01 01 01 01 01 - - -45-49 02 03 02 02 03 01 03 03 0350-54 04 04 03 04 05 03 04 03 0555-59 06 07 06 06 07 05 05 04 0660-64 11 12 10 11 12 09 12 09 1465-69 16 17 15 16 17 14 16 14 1870-74 22 22 21 21 22 21 25 20 2875-79 31 32 31 31 33 30 30 28 3180-84 43 42 43 42 43 41 37 23 4585+ 57 54 59 57 56 57 54 26 66

Table 267Cancer of the Thyroid (Invasive)

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2015 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2015

d Period survival provides a 2014 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2008-2014 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 83 75 87 - - -1970-1973a - - - 86 82 87 - - -1975-1977b 921 911 925 918 907 922 898 - 9101978-1980b 921 872 936 915 875 927 902 680h 9551981-1983b 936 922 939 931 909 937 964 1000 9321984-1986b 932 898 943 932 894 944 893 855g 9031987-1989b 944 916 952 941 916 950 923 912g 9231990-1992b 943 905 955 949 916 960 859 845g 8631993-1995b 954 916 967 956 915 969 932 878g 9431996-1998b 956 910 969 959 913 973 951 865g 9661999-2001b 965 943 971 968 949 974 920 884g 9242002-2004b 973 939 982 974 941 983 959 942 9602005-2007b 979 961 985 980 961 986 963 915 9692008-2014b 983f 960f 989f 986f 965f 992f 970f 913 979f

5-Year Period Survival (Percent)cd

2014 982 958 989 984 961 990 969 928 974

Stage Distribution () 2008-2014ce

All StagesNumber of cases 74280 17072 57208 59623 14147 45476 5139 909 4230Percent 100 100 100 100 100 100 100 100 100Localized 67 58 70 67 58 70 80 72 81Regional 27 33 25 27 34 25 14 18 13Distant 4 7 3 4 6 3 4 8 4UnstagedUnknown 2 2 2 2 2 2 2 2 2

5-Year Relative Survival (Percent) 2008-2014c

Age at DiagnosisAges lt45 997 991 998 997 993 998 992 965 995Ages 45-54 988 962 995 988 964 995 990 959 995Ages 55-64 980 952 989 983 953 992 956 920 963Ages 65-74 963 917 974 966 923 977 939 822g 965Ages 75+ 863 847 867 884 863 888 754 728g 739Ages lt65 991 971 996 991 972 996 983 952 990Ages 65+ 932 896 943 942 905 949 889 824g 903

StageeAll Stages 981 956 988 983 958 990 972 929 977Localized 999 998 1000 999 998 1000 998 989 999Regional 980 964 987 982 966 989 944 896 958Distant 555 509 583 558 507 592 470 424g 487UnstagedUnknown 891 836 909 884 845 897 887 - 915

Table 268Cancer of the Thyroid (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 949 951 959 962 967 968 964 977 972 976 976 971 979 983 977 985 985 983 988 989 987 988 983 9872-year 935 945 952 957 961 966 962 971 971 970 974 971 979 979 973 984 981 982 987 986 986 984 9823-year 929 937 948 953 960 960 962 969 971 969 970 971 977 979 973 983 980 982 987 985 986 9844-year 925 934 943 950 959 954 956 963 970 969 970 971 974 977 973 983 979 980 987 984 9865-year 921 933 941 947 958 949 953 962 969 963 962 971 973 973 973 982 979 978 987 9816-year 916 931 938 943 958 948 952 958 964 963 962 967 970 972 973 982 979 978 9877-year 914 927 934 942 956 945 952 958 962 961 961 965 968 969 973 981 979 9788-year 911 926 933 941 955 942 951 958 960 959 959 963 967 968 973 980 9799-year 907 923 931 939 955 937 949 958 956 959 954 963 967 968 973 98010-year 905 920 928 936 951 936 949 958 954 958 954 963 967 967 97311-year 903 917 927 933 950 933 949 958 950 958 954 961 967 96512-year 903 914 926 930 950 930 949 958 948 958 954 959 96713-year 900 912 925 930 950 928 949 950 947 958 954 95914-year 899 912 924 927 950 926 949 946 946 958 95415-year 897 907 923 923 943 924 949 941 945 95816-year 896 906 923 922 938 924 949 938 94517-year 895 906 922 922 938 923 949 93718-year 893 905 922 921 938 923 94319-year 892 905 919 921 938 92320-year 892 905 919 921 938

Table 269Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 946 925 948 946 934 937 918 972 965 963 961 951 956 967 971 964 973 968 983 978 973 979 967 9712-year 925 920 937 932 919 934 909 954 962 949 955 949 953 951 956 961 965 961 982 963 969 972 9643-year 915 908 935 924 917 921 909 947 962 949 942 949 942 948 956 961 965 961 982 961 967 9684-year 905 904 921 919 914 917 895 937 962 949 936 946 935 943 956 961 965 957 982 956 9675-year 899 902 916 910 912 898 882 937 962 938 924 943 932 940 956 957 963 951 980 9436-year 896 898 911 906 903 898 880 935 958 938 920 938 917 940 956 957 963 951 9787-year 894 893 900 904 887 895 880 933 954 934 919 924 917 928 956 953 963 9498-year 893 893 896 901 887 885 878 933 952 934 911 915 917 925 953 953 9639-year 888 886 885 899 887 867 869 933 930 934 898 910 917 921 953 95310-year 883 879 885 897 874 864 869 933 926 934 896 910 917 915 94911-year 875 872 884 895 862 848 865 933 926 934 896 902 917 91512-year 875 864 883 887 860 841 865 931 926 934 893 899 91713-year 873 862 878 882 860 831 865 931 926 927 893 89914-year 873 862 877 878 858 827 865 931 926 927 89315-year 867 854 877 872 858 827 865 931 926 92416-year 866 853 877 868 858 827 865 923 92617-year 866 849 877 868 858 827 865 91818-year 866 846 877 865 858 827 86019-year 866 846 877 864 858 82220-year 866 846 877 864 858

Table 2610Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 950 960 963 968 978 977 977 979 974 980 980 977 986 988 979 990 989 987 989 991 991 991 988 9912-year 939 953 957 966 974 975 977 976 974 977 980 977 985 987 979 990 985 987 988 991 991 988 9873-year 933 947 952 963 973 971 977 975 974 975 977 977 985 987 979 989 985 987 988 991 991 9884-year 931 944 950 961 973 965 975 971 972 975 977 977 985 987 979 989 983 986 987 991 9905-year 927 943 949 959 972 964 974 969 969 970 973 977 984 983 979 989 983 986 987 9906-year 923 942 947 955 972 961 973 965 965 970 973 976 983 981 979 989 983 986 9877-year 921 938 945 954 972 959 973 965 963 970 973 976 981 980 979 989 983 9858-year 917 937 945 954 972 959 973 965 962 966 973 976 980 980 979 987 9839-year 913 936 945 953 972 958 973 965 962 966 970 976 979 980 979 98710-year 912 934 942 949 972 957 973 965 960 964 970 976 977 980 97911-year 912 932 940 946 972 957 973 965 958 964 970 976 977 97912-year 911 931 940 945 972 955 973 965 952 964 970 976 97713-year 909 929 940 944 972 955 973 955 949 964 970 97614-year 908 928 939 943 972 955 973 949 946 964 97015-year 907 924 938 940 967 950 973 943 944 96416-year 906 923 937 939 958 950 973 942 94417-year 904 923 936 939 958 950 971 94118-year 899 923 935 938 958 950 96719-year 898 923 932 938 958 95020-year 898 923 932 938 958

Table 2611Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 002 011 122 006 Asian 0 000 002 010 128 011

10 002 011 029 123 006 Pacific 10 002 010 027 129 011

20 009 027 049 121 006 Islander 20 008 024 047 127 011

30 018 040 065 114 007 30 017 039 063 120 011

40 023 047 072 097 007 40 022 046 072 104 011

50 025 050 068 077 007 50 024 051 070 083 011

60 026 046 053 054 006 60 027 047 058 060 011

70 022 030 - 032 006 70 021 032 - 035 010

80 011 - - 013 005 80 013 - - 017 008

White 0 000 003 012 128 006 American 0 000 002 007 083 007

10 003 012 031 129 006 Indian 10 002 007 018 084 007

20 010 029 052 127 006 Alaska 20 005 016 026 083 007

30 019 043 069 118 006 Nativea 30 011 021 036 079 007

40 024 050 074 100 006 40 010 026 043 070 007

50 027 052 071 079 006 50 016 034 048 063 008

60 027 047 054 055 006 60 019 034 047 050 007

70 022 031 - 032 006 70 017 032 - 035 007

80 011 - - 013 005 80 020 - - 024 009

Black 0 000 001 004 074 006 Hispanicb 0 000 002 009 114 009

10 001 004 012 076 006 10 002 009 023 115 009

20 003 012 026 075 006 20 007 021 040 113 009

30 009 023 038 073 006 30 014 033 055 107 009

40 015 030 048 066 006 40 019 042 065 094 010

50 016 034 046 053 006 50 023 047 067 077 010

60 020 033 039 040 006 60 025 045 053 056 009

70 016 023 - 025 006 70 022 031 - 034 009

80 010 - - 013 005 80 011 - - 014 007

Table 2612

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 001 004 064 006 Asian 0 000 001 004 067 008

10 001 004 010 065 006 Pacific 10 001 004 010 067 008

20 003 009 019 064 006 Islander 20 003 009 020 066 008

30 007 016 029 062 006 30 007 017 028 064 008

40 010 022 038 056 006 40 010 021 036 058 008

50 013 029 042 048 006 50 011 026 039 048 008

60 017 031 037 038 006 60 016 029 038 038 008

70 016 023 - 024 005 70 015 024 - 025 007

80 010 - - 011 004 80 011 - - 012 006

White 0 000 001 004 068 006 American 0 000 001 003 034 006

10 001 004 011 069 006 Indian 10 001 003 006 035 006

20 003 010 020 068 006 Alaska 20 002 005 008 034 006

30 007 017 031 066 006 Nativea 30 003 006 010 033 006

40 010 024 040 060 006 40 002 007 015 030 006

50 014 031 045 051 006 50 005 013 022 030 007

60 018 033 039 039 006 60 009 019 027 027 007

70 017 024 - 025 005 70 011 020 - 021 007

80 010 - - 011 004 80 013 - - 014 008

Black 0 000 000 001 031 003 Hispanicb 0 000 001 003 050 007

10 000 001 004 031 004 10 001 003 007 050 007

20 001 003 008 031 004 20 002 006 012 050 007

30 003 007 014 031 004 30 004 011 020 048 007

40 004 012 020 029 004 40 006 016 028 045 007

50 008 016 023 026 004 50 010 022 033 039 007

60 010 017 021 021 004 60 013 025 030 031 007

70 010 014 - 014 003 70 013 019 - 020 006

80 007 - - 007 002 80 008 - - 010 005

Table 2613

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 004 019 181 007 Asian 0 000 003 016 183 013

10 004 018 048 182 007 Pacific 10 003 016 042 184 013

20 015 044 079 179 007 Islander 20 013 039 072 181 013

30 030 065 101 165 007 30 026 059 094 169 013

40 036 072 105 137 007 40 033 068 104 144 013

50 037 071 094 104 007 50 035 071 096 112 013

60 035 059 068 070 007 60 037 062 074 079 013

70 027 036 - 038 006 70 027 039 - 044 012

80 012 - - 015 005 80 015 - - 020 009

White 0 000 004 021 190 007 American 0 000 003 011 132 008

10 004 021 053 192 007 Indian 10 002 011 030 133 008

20 017 049 086 188 007 Alaska 20 009 027 044 131 008

30 032 070 108 172 007 Nativea 30 019 036 062 124 008

40 038 076 109 141 007 40 017 044 069 107 008

50 039 073 097 106 007 50 027 054 073 093 008

60 035 060 069 070 007 60 028 048 065 069 007

70 027 037 - 038 006 70 022 041 - 046 007

80 012 - - 014 005 80 024 - - 030 008

Black 0 000 001 007 114 008 Hispanicb 0 000 004 017 179 011

10 001 007 021 116 008 10 004 017 041 180 011

20 006 020 043 116 008 20 013 038 069 177 011

30 015 038 061 111 008 30 025 056 092 165 011

40 024 047 072 098 008 40 031 068 102 141 011

50 024 050 067 076 008 50 037 072 098 111 011

60 028 046 054 056 008 60 036 063 074 077 011

70 021 030 - 033 008 70 030 041 - 044 010

80 012 - - 016 006 80 014 - - 017 008

Table 2614

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 5: SEER Cancer Statistics Review 1975-2015

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2015 870 466 1259 890 484 1293 550 259 7931975-1979 493 307 669 482 293 662 327 164 4631980 433 239 615 429 228 620 237 - 3431981 442 252 624 439 248 628 239 - 3441982 463 300 615 453 287 609 329 - 4341983 471 280 650 474 261 673 302 215 3771984 485 265 693 473 258 681 302 - 4081985 513 310 709 509 310 704 286 - 3661986 533 307 750 525 310 737 335 - 5091987 504 281 712 502 286 706 282 - 4301988 493 294 688 489 300 678 253 - 3211989 537 299 766 547 322 770 263 - 4141990 549 293 795 555 299 807 376 228 4911991 549 319 769 570 331 804 322 207 4201992 588 352 813 588 352 817 423 309 5181993 565 359 764 574 368 777 338 207 4561994 609 339 875 624 344 903 375 178 5351995 623 337 902 642 359 923 308 - 4611996 652 347 951 672 361 983 389 179 5801997 678 366 980 706 377 1034 398 244 5241998 699 372 1012 720 395 1041 403 150 6111999 735 387 1068 756 408 1098 459 160 7012000 762 404 1110 805 438 1177 457 218 6552001 831 434 1218 868 462 1278 493 252 6882002 924 495 1343 976 527 1429 552 285 7682003 966 472 1448 1038 506 1571 530 282 7512004 1015 524 1494 1082 555 1613 637 333 8902005 1098 581 1599 1195 648 1743 592 276 8682006 1133 586 1663 1217 637 1800 664 315 9472007 1241 612 1853 1328 656 2005 726 322 10602008 1323 658 1968 1422 706 2144 707 448 9482009 1448 708 2159 1554 773 2334 861 338 13112010 1395 665 2102 1476 726 2232 865 340 12982011 1480 741 2196 1572 797 2350 908 378 13442012 1498 804 2179 1583 865 2313 959 431 14042013 1514 776 2233 1631 839 2434 910 397 13512014 1514 771 2238 1618 824 2423 962 425 14212015 1503 766 2226 1614 849 2397 874 310 1336

Table 265Cancer of the Thyroid (Invasive)

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2015 048 045 050 048 046 048 048 035 0561975-1979 055 044 061 055 045 061 052 038 0621980 048 038 053 049 040 054 042 029 0511981 050 042 055 050 043 054 048 026 0621982 048 037 053 047 037 053 048 038 0541983 044 034 050 045 035 050 041 028 0491984 047 038 052 047 039 051 047 - 0641985 045 039 048 044 039 046 049 034 0581986 046 039 049 045 039 049 048 034 0571987 045 040 048 045 041 047 048 033 0581988 044 041 045 044 042 044 044 033 0501989 044 041 044 043 041 043 051 040 0561990 044 037 048 044 038 047 045 030 0541991 043 038 046 042 039 043 050 037 0581992 046 038 050 046 039 048 041 030 0481993 046 039 050 046 040 048 046 026 0581994 042 038 044 042 038 044 037 030 0401995 044 041 044 044 043 044 040 027 0461996 045 042 047 045 043 046 044 033 0491997 046 045 046 045 045 044 049 037 0551998 044 038 047 043 039 045 043 027 0531999 045 044 045 045 045 044 044 039 0472000 048 047 048 047 048 045 051 034 0592001 048 047 048 047 048 046 051 041 0582002 048 045 048 048 046 048 048 039 0522003 045 043 046 046 045 046 038 029 0442004 048 047 047 048 048 047 045 040 0482005 048 048 049 048 050 046 051 030 0642006 049 046 051 050 048 050 047 028 0602007 050 051 048 048 051 046 050 040 0562008 052 050 052 052 052 051 046 040 0512009 052 051 052 051 052 050 057 041 0662010 051 050 051 050 051 048 049 045 0532011 051 052 049 051 054 048 044 032 0512012 048 051 046 048 052 045 049 041 0542013 052 053 050 051 054 048 052 039 0612014 050 049 050 050 052 048 056 038 0662015 051 054 048 050 055 046 049 041 053

Table 266Cancer of the Thyroid (Invasive)

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a SEER 18 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2011-2015All ages 145 73 214 153 78 228 89 38 134Under 65 132 58 205 141 63 220 76 27 12065 and over 231 175 278 235 182 282 181 114 228

All ages (WHO world std)c 128 62 192 135 66 205 76 31 116

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 02 - 02 02 - 03 - - -10-14 09 05 14 11 05 16 - - -15-19 31 09 53 34 10 60 11 - 1820-24 62 20 107 71 23 124 17 - 3225-29 105 35 179 117 40 200 42 11 7230-34 160 57 264 175 63 291 67 16 11335-39 201 74 328 214 78 354 111 32 18240-44 220 91 347 230 97 367 146 48 23345-49 236 109 362 249 117 382 144 47 23150-54 256 123 385 270 133 407 152 59 23455-59 262 144 373 275 154 393 172 89 24360-64 260 163 348 267 174 355 203 91 29565-69 290 199 370 294 207 373 225 127 30070-74 259 195 313 268 204 323 195 131 24175-79 231 177 272 237 184 280 179 118 22080-84 174 157 186 175 161 186 129 106 14185+ 110 96 117 107 99 111 122 - 153

US MortalityAge at DeathAge-Adjusted Rates 2011-2015All ages 05 05 05 05 05 05 05 04 06Under 65 01 02 01 01 02 01 02 01 0265 and over 30 30 29 29 30 28 29 21 33

All ages (WHO world std)c 03 04 03 03 04 03 03 03 04

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 00 - - 00 - - - - -30-34 00 00 - 00 - - - - -35-39 00 00 00 00 00 - - - -40-44 01 01 01 01 01 01 - - -45-49 02 03 02 02 03 01 03 03 0350-54 04 04 03 04 05 03 04 03 0555-59 06 07 06 06 07 05 05 04 0660-64 11 12 10 11 12 09 12 09 1465-69 16 17 15 16 17 14 16 14 1870-74 22 22 21 21 22 21 25 20 2875-79 31 32 31 31 33 30 30 28 3180-84 43 42 43 42 43 41 37 23 4585+ 57 54 59 57 56 57 54 26 66

Table 267Cancer of the Thyroid (Invasive)

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2015 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2015

d Period survival provides a 2014 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2008-2014 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 83 75 87 - - -1970-1973a - - - 86 82 87 - - -1975-1977b 921 911 925 918 907 922 898 - 9101978-1980b 921 872 936 915 875 927 902 680h 9551981-1983b 936 922 939 931 909 937 964 1000 9321984-1986b 932 898 943 932 894 944 893 855g 9031987-1989b 944 916 952 941 916 950 923 912g 9231990-1992b 943 905 955 949 916 960 859 845g 8631993-1995b 954 916 967 956 915 969 932 878g 9431996-1998b 956 910 969 959 913 973 951 865g 9661999-2001b 965 943 971 968 949 974 920 884g 9242002-2004b 973 939 982 974 941 983 959 942 9602005-2007b 979 961 985 980 961 986 963 915 9692008-2014b 983f 960f 989f 986f 965f 992f 970f 913 979f

5-Year Period Survival (Percent)cd

2014 982 958 989 984 961 990 969 928 974

Stage Distribution () 2008-2014ce

All StagesNumber of cases 74280 17072 57208 59623 14147 45476 5139 909 4230Percent 100 100 100 100 100 100 100 100 100Localized 67 58 70 67 58 70 80 72 81Regional 27 33 25 27 34 25 14 18 13Distant 4 7 3 4 6 3 4 8 4UnstagedUnknown 2 2 2 2 2 2 2 2 2

5-Year Relative Survival (Percent) 2008-2014c

Age at DiagnosisAges lt45 997 991 998 997 993 998 992 965 995Ages 45-54 988 962 995 988 964 995 990 959 995Ages 55-64 980 952 989 983 953 992 956 920 963Ages 65-74 963 917 974 966 923 977 939 822g 965Ages 75+ 863 847 867 884 863 888 754 728g 739Ages lt65 991 971 996 991 972 996 983 952 990Ages 65+ 932 896 943 942 905 949 889 824g 903

StageeAll Stages 981 956 988 983 958 990 972 929 977Localized 999 998 1000 999 998 1000 998 989 999Regional 980 964 987 982 966 989 944 896 958Distant 555 509 583 558 507 592 470 424g 487UnstagedUnknown 891 836 909 884 845 897 887 - 915

Table 268Cancer of the Thyroid (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 949 951 959 962 967 968 964 977 972 976 976 971 979 983 977 985 985 983 988 989 987 988 983 9872-year 935 945 952 957 961 966 962 971 971 970 974 971 979 979 973 984 981 982 987 986 986 984 9823-year 929 937 948 953 960 960 962 969 971 969 970 971 977 979 973 983 980 982 987 985 986 9844-year 925 934 943 950 959 954 956 963 970 969 970 971 974 977 973 983 979 980 987 984 9865-year 921 933 941 947 958 949 953 962 969 963 962 971 973 973 973 982 979 978 987 9816-year 916 931 938 943 958 948 952 958 964 963 962 967 970 972 973 982 979 978 9877-year 914 927 934 942 956 945 952 958 962 961 961 965 968 969 973 981 979 9788-year 911 926 933 941 955 942 951 958 960 959 959 963 967 968 973 980 9799-year 907 923 931 939 955 937 949 958 956 959 954 963 967 968 973 98010-year 905 920 928 936 951 936 949 958 954 958 954 963 967 967 97311-year 903 917 927 933 950 933 949 958 950 958 954 961 967 96512-year 903 914 926 930 950 930 949 958 948 958 954 959 96713-year 900 912 925 930 950 928 949 950 947 958 954 95914-year 899 912 924 927 950 926 949 946 946 958 95415-year 897 907 923 923 943 924 949 941 945 95816-year 896 906 923 922 938 924 949 938 94517-year 895 906 922 922 938 923 949 93718-year 893 905 922 921 938 923 94319-year 892 905 919 921 938 92320-year 892 905 919 921 938

Table 269Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 946 925 948 946 934 937 918 972 965 963 961 951 956 967 971 964 973 968 983 978 973 979 967 9712-year 925 920 937 932 919 934 909 954 962 949 955 949 953 951 956 961 965 961 982 963 969 972 9643-year 915 908 935 924 917 921 909 947 962 949 942 949 942 948 956 961 965 961 982 961 967 9684-year 905 904 921 919 914 917 895 937 962 949 936 946 935 943 956 961 965 957 982 956 9675-year 899 902 916 910 912 898 882 937 962 938 924 943 932 940 956 957 963 951 980 9436-year 896 898 911 906 903 898 880 935 958 938 920 938 917 940 956 957 963 951 9787-year 894 893 900 904 887 895 880 933 954 934 919 924 917 928 956 953 963 9498-year 893 893 896 901 887 885 878 933 952 934 911 915 917 925 953 953 9639-year 888 886 885 899 887 867 869 933 930 934 898 910 917 921 953 95310-year 883 879 885 897 874 864 869 933 926 934 896 910 917 915 94911-year 875 872 884 895 862 848 865 933 926 934 896 902 917 91512-year 875 864 883 887 860 841 865 931 926 934 893 899 91713-year 873 862 878 882 860 831 865 931 926 927 893 89914-year 873 862 877 878 858 827 865 931 926 927 89315-year 867 854 877 872 858 827 865 931 926 92416-year 866 853 877 868 858 827 865 923 92617-year 866 849 877 868 858 827 865 91818-year 866 846 877 865 858 827 86019-year 866 846 877 864 858 82220-year 866 846 877 864 858

Table 2610Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 950 960 963 968 978 977 977 979 974 980 980 977 986 988 979 990 989 987 989 991 991 991 988 9912-year 939 953 957 966 974 975 977 976 974 977 980 977 985 987 979 990 985 987 988 991 991 988 9873-year 933 947 952 963 973 971 977 975 974 975 977 977 985 987 979 989 985 987 988 991 991 9884-year 931 944 950 961 973 965 975 971 972 975 977 977 985 987 979 989 983 986 987 991 9905-year 927 943 949 959 972 964 974 969 969 970 973 977 984 983 979 989 983 986 987 9906-year 923 942 947 955 972 961 973 965 965 970 973 976 983 981 979 989 983 986 9877-year 921 938 945 954 972 959 973 965 963 970 973 976 981 980 979 989 983 9858-year 917 937 945 954 972 959 973 965 962 966 973 976 980 980 979 987 9839-year 913 936 945 953 972 958 973 965 962 966 970 976 979 980 979 98710-year 912 934 942 949 972 957 973 965 960 964 970 976 977 980 97911-year 912 932 940 946 972 957 973 965 958 964 970 976 977 97912-year 911 931 940 945 972 955 973 965 952 964 970 976 97713-year 909 929 940 944 972 955 973 955 949 964 970 97614-year 908 928 939 943 972 955 973 949 946 964 97015-year 907 924 938 940 967 950 973 943 944 96416-year 906 923 937 939 958 950 973 942 94417-year 904 923 936 939 958 950 971 94118-year 899 923 935 938 958 950 96719-year 898 923 932 938 958 95020-year 898 923 932 938 958

Table 2611Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 002 011 122 006 Asian 0 000 002 010 128 011

10 002 011 029 123 006 Pacific 10 002 010 027 129 011

20 009 027 049 121 006 Islander 20 008 024 047 127 011

30 018 040 065 114 007 30 017 039 063 120 011

40 023 047 072 097 007 40 022 046 072 104 011

50 025 050 068 077 007 50 024 051 070 083 011

60 026 046 053 054 006 60 027 047 058 060 011

70 022 030 - 032 006 70 021 032 - 035 010

80 011 - - 013 005 80 013 - - 017 008

White 0 000 003 012 128 006 American 0 000 002 007 083 007

10 003 012 031 129 006 Indian 10 002 007 018 084 007

20 010 029 052 127 006 Alaska 20 005 016 026 083 007

30 019 043 069 118 006 Nativea 30 011 021 036 079 007

40 024 050 074 100 006 40 010 026 043 070 007

50 027 052 071 079 006 50 016 034 048 063 008

60 027 047 054 055 006 60 019 034 047 050 007

70 022 031 - 032 006 70 017 032 - 035 007

80 011 - - 013 005 80 020 - - 024 009

Black 0 000 001 004 074 006 Hispanicb 0 000 002 009 114 009

10 001 004 012 076 006 10 002 009 023 115 009

20 003 012 026 075 006 20 007 021 040 113 009

30 009 023 038 073 006 30 014 033 055 107 009

40 015 030 048 066 006 40 019 042 065 094 010

50 016 034 046 053 006 50 023 047 067 077 010

60 020 033 039 040 006 60 025 045 053 056 009

70 016 023 - 025 006 70 022 031 - 034 009

80 010 - - 013 005 80 011 - - 014 007

Table 2612

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 001 004 064 006 Asian 0 000 001 004 067 008

10 001 004 010 065 006 Pacific 10 001 004 010 067 008

20 003 009 019 064 006 Islander 20 003 009 020 066 008

30 007 016 029 062 006 30 007 017 028 064 008

40 010 022 038 056 006 40 010 021 036 058 008

50 013 029 042 048 006 50 011 026 039 048 008

60 017 031 037 038 006 60 016 029 038 038 008

70 016 023 - 024 005 70 015 024 - 025 007

80 010 - - 011 004 80 011 - - 012 006

White 0 000 001 004 068 006 American 0 000 001 003 034 006

10 001 004 011 069 006 Indian 10 001 003 006 035 006

20 003 010 020 068 006 Alaska 20 002 005 008 034 006

30 007 017 031 066 006 Nativea 30 003 006 010 033 006

40 010 024 040 060 006 40 002 007 015 030 006

50 014 031 045 051 006 50 005 013 022 030 007

60 018 033 039 039 006 60 009 019 027 027 007

70 017 024 - 025 005 70 011 020 - 021 007

80 010 - - 011 004 80 013 - - 014 008

Black 0 000 000 001 031 003 Hispanicb 0 000 001 003 050 007

10 000 001 004 031 004 10 001 003 007 050 007

20 001 003 008 031 004 20 002 006 012 050 007

30 003 007 014 031 004 30 004 011 020 048 007

40 004 012 020 029 004 40 006 016 028 045 007

50 008 016 023 026 004 50 010 022 033 039 007

60 010 017 021 021 004 60 013 025 030 031 007

70 010 014 - 014 003 70 013 019 - 020 006

80 007 - - 007 002 80 008 - - 010 005

Table 2613

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 004 019 181 007 Asian 0 000 003 016 183 013

10 004 018 048 182 007 Pacific 10 003 016 042 184 013

20 015 044 079 179 007 Islander 20 013 039 072 181 013

30 030 065 101 165 007 30 026 059 094 169 013

40 036 072 105 137 007 40 033 068 104 144 013

50 037 071 094 104 007 50 035 071 096 112 013

60 035 059 068 070 007 60 037 062 074 079 013

70 027 036 - 038 006 70 027 039 - 044 012

80 012 - - 015 005 80 015 - - 020 009

White 0 000 004 021 190 007 American 0 000 003 011 132 008

10 004 021 053 192 007 Indian 10 002 011 030 133 008

20 017 049 086 188 007 Alaska 20 009 027 044 131 008

30 032 070 108 172 007 Nativea 30 019 036 062 124 008

40 038 076 109 141 007 40 017 044 069 107 008

50 039 073 097 106 007 50 027 054 073 093 008

60 035 060 069 070 007 60 028 048 065 069 007

70 027 037 - 038 006 70 022 041 - 046 007

80 012 - - 014 005 80 024 - - 030 008

Black 0 000 001 007 114 008 Hispanicb 0 000 004 017 179 011

10 001 007 021 116 008 10 004 017 041 180 011

20 006 020 043 116 008 20 013 038 069 177 011

30 015 038 061 111 008 30 025 056 092 165 011

40 024 047 072 098 008 40 031 068 102 141 011

50 024 050 067 076 008 50 037 072 098 111 011

60 028 046 054 056 008 60 036 063 074 077 011

70 021 030 - 033 008 70 030 041 - 044 010

80 012 - - 016 006 80 014 - - 017 008

Table 2614

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

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1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

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Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

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ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

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ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

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Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 6: SEER Cancer Statistics Review 1975-2015

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Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2015 048 045 050 048 046 048 048 035 0561975-1979 055 044 061 055 045 061 052 038 0621980 048 038 053 049 040 054 042 029 0511981 050 042 055 050 043 054 048 026 0621982 048 037 053 047 037 053 048 038 0541983 044 034 050 045 035 050 041 028 0491984 047 038 052 047 039 051 047 - 0641985 045 039 048 044 039 046 049 034 0581986 046 039 049 045 039 049 048 034 0571987 045 040 048 045 041 047 048 033 0581988 044 041 045 044 042 044 044 033 0501989 044 041 044 043 041 043 051 040 0561990 044 037 048 044 038 047 045 030 0541991 043 038 046 042 039 043 050 037 0581992 046 038 050 046 039 048 041 030 0481993 046 039 050 046 040 048 046 026 0581994 042 038 044 042 038 044 037 030 0401995 044 041 044 044 043 044 040 027 0461996 045 042 047 045 043 046 044 033 0491997 046 045 046 045 045 044 049 037 0551998 044 038 047 043 039 045 043 027 0531999 045 044 045 045 045 044 044 039 0472000 048 047 048 047 048 045 051 034 0592001 048 047 048 047 048 046 051 041 0582002 048 045 048 048 046 048 048 039 0522003 045 043 046 046 045 046 038 029 0442004 048 047 047 048 048 047 045 040 0482005 048 048 049 048 050 046 051 030 0642006 049 046 051 050 048 050 047 028 0602007 050 051 048 048 051 046 050 040 0562008 052 050 052 052 052 051 046 040 0512009 052 051 052 051 052 050 057 041 0662010 051 050 051 050 051 048 049 045 0532011 051 052 049 051 054 048 044 032 0512012 048 051 046 048 052 045 049 041 0542013 052 053 050 051 054 048 052 039 0612014 050 049 050 050 052 048 056 038 0662015 051 054 048 050 055 046 049 041 053

Table 266Cancer of the Thyroid (Invasive)

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

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1975-2015N

ational Cancer Institute

a SEER 18 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2011-2015All ages 145 73 214 153 78 228 89 38 134Under 65 132 58 205 141 63 220 76 27 12065 and over 231 175 278 235 182 282 181 114 228

All ages (WHO world std)c 128 62 192 135 66 205 76 31 116

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 02 - 02 02 - 03 - - -10-14 09 05 14 11 05 16 - - -15-19 31 09 53 34 10 60 11 - 1820-24 62 20 107 71 23 124 17 - 3225-29 105 35 179 117 40 200 42 11 7230-34 160 57 264 175 63 291 67 16 11335-39 201 74 328 214 78 354 111 32 18240-44 220 91 347 230 97 367 146 48 23345-49 236 109 362 249 117 382 144 47 23150-54 256 123 385 270 133 407 152 59 23455-59 262 144 373 275 154 393 172 89 24360-64 260 163 348 267 174 355 203 91 29565-69 290 199 370 294 207 373 225 127 30070-74 259 195 313 268 204 323 195 131 24175-79 231 177 272 237 184 280 179 118 22080-84 174 157 186 175 161 186 129 106 14185+ 110 96 117 107 99 111 122 - 153

US MortalityAge at DeathAge-Adjusted Rates 2011-2015All ages 05 05 05 05 05 05 05 04 06Under 65 01 02 01 01 02 01 02 01 0265 and over 30 30 29 29 30 28 29 21 33

All ages (WHO world std)c 03 04 03 03 04 03 03 03 04

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 00 - - 00 - - - - -30-34 00 00 - 00 - - - - -35-39 00 00 00 00 00 - - - -40-44 01 01 01 01 01 01 - - -45-49 02 03 02 02 03 01 03 03 0350-54 04 04 03 04 05 03 04 03 0555-59 06 07 06 06 07 05 05 04 0660-64 11 12 10 11 12 09 12 09 1465-69 16 17 15 16 17 14 16 14 1870-74 22 22 21 21 22 21 25 20 2875-79 31 32 31 31 33 30 30 28 3180-84 43 42 43 42 43 41 37 23 4585+ 57 54 59 57 56 57 54 26 66

Table 267Cancer of the Thyroid (Invasive)

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

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1975-2015N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2015 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2015

d Period survival provides a 2014 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2008-2014 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 83 75 87 - - -1970-1973a - - - 86 82 87 - - -1975-1977b 921 911 925 918 907 922 898 - 9101978-1980b 921 872 936 915 875 927 902 680h 9551981-1983b 936 922 939 931 909 937 964 1000 9321984-1986b 932 898 943 932 894 944 893 855g 9031987-1989b 944 916 952 941 916 950 923 912g 9231990-1992b 943 905 955 949 916 960 859 845g 8631993-1995b 954 916 967 956 915 969 932 878g 9431996-1998b 956 910 969 959 913 973 951 865g 9661999-2001b 965 943 971 968 949 974 920 884g 9242002-2004b 973 939 982 974 941 983 959 942 9602005-2007b 979 961 985 980 961 986 963 915 9692008-2014b 983f 960f 989f 986f 965f 992f 970f 913 979f

5-Year Period Survival (Percent)cd

2014 982 958 989 984 961 990 969 928 974

Stage Distribution () 2008-2014ce

All StagesNumber of cases 74280 17072 57208 59623 14147 45476 5139 909 4230Percent 100 100 100 100 100 100 100 100 100Localized 67 58 70 67 58 70 80 72 81Regional 27 33 25 27 34 25 14 18 13Distant 4 7 3 4 6 3 4 8 4UnstagedUnknown 2 2 2 2 2 2 2 2 2

5-Year Relative Survival (Percent) 2008-2014c

Age at DiagnosisAges lt45 997 991 998 997 993 998 992 965 995Ages 45-54 988 962 995 988 964 995 990 959 995Ages 55-64 980 952 989 983 953 992 956 920 963Ages 65-74 963 917 974 966 923 977 939 822g 965Ages 75+ 863 847 867 884 863 888 754 728g 739Ages lt65 991 971 996 991 972 996 983 952 990Ages 65+ 932 896 943 942 905 949 889 824g 903

StageeAll Stages 981 956 988 983 958 990 972 929 977Localized 999 998 1000 999 998 1000 998 989 999Regional 980 964 987 982 966 989 944 896 958Distant 555 509 583 558 507 592 470 424g 487UnstagedUnknown 891 836 909 884 845 897 887 - 915

Table 268Cancer of the Thyroid (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 949 951 959 962 967 968 964 977 972 976 976 971 979 983 977 985 985 983 988 989 987 988 983 9872-year 935 945 952 957 961 966 962 971 971 970 974 971 979 979 973 984 981 982 987 986 986 984 9823-year 929 937 948 953 960 960 962 969 971 969 970 971 977 979 973 983 980 982 987 985 986 9844-year 925 934 943 950 959 954 956 963 970 969 970 971 974 977 973 983 979 980 987 984 9865-year 921 933 941 947 958 949 953 962 969 963 962 971 973 973 973 982 979 978 987 9816-year 916 931 938 943 958 948 952 958 964 963 962 967 970 972 973 982 979 978 9877-year 914 927 934 942 956 945 952 958 962 961 961 965 968 969 973 981 979 9788-year 911 926 933 941 955 942 951 958 960 959 959 963 967 968 973 980 9799-year 907 923 931 939 955 937 949 958 956 959 954 963 967 968 973 98010-year 905 920 928 936 951 936 949 958 954 958 954 963 967 967 97311-year 903 917 927 933 950 933 949 958 950 958 954 961 967 96512-year 903 914 926 930 950 930 949 958 948 958 954 959 96713-year 900 912 925 930 950 928 949 950 947 958 954 95914-year 899 912 924 927 950 926 949 946 946 958 95415-year 897 907 923 923 943 924 949 941 945 95816-year 896 906 923 922 938 924 949 938 94517-year 895 906 922 922 938 923 949 93718-year 893 905 922 921 938 923 94319-year 892 905 919 921 938 92320-year 892 905 919 921 938

Table 269Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 946 925 948 946 934 937 918 972 965 963 961 951 956 967 971 964 973 968 983 978 973 979 967 9712-year 925 920 937 932 919 934 909 954 962 949 955 949 953 951 956 961 965 961 982 963 969 972 9643-year 915 908 935 924 917 921 909 947 962 949 942 949 942 948 956 961 965 961 982 961 967 9684-year 905 904 921 919 914 917 895 937 962 949 936 946 935 943 956 961 965 957 982 956 9675-year 899 902 916 910 912 898 882 937 962 938 924 943 932 940 956 957 963 951 980 9436-year 896 898 911 906 903 898 880 935 958 938 920 938 917 940 956 957 963 951 9787-year 894 893 900 904 887 895 880 933 954 934 919 924 917 928 956 953 963 9498-year 893 893 896 901 887 885 878 933 952 934 911 915 917 925 953 953 9639-year 888 886 885 899 887 867 869 933 930 934 898 910 917 921 953 95310-year 883 879 885 897 874 864 869 933 926 934 896 910 917 915 94911-year 875 872 884 895 862 848 865 933 926 934 896 902 917 91512-year 875 864 883 887 860 841 865 931 926 934 893 899 91713-year 873 862 878 882 860 831 865 931 926 927 893 89914-year 873 862 877 878 858 827 865 931 926 927 89315-year 867 854 877 872 858 827 865 931 926 92416-year 866 853 877 868 858 827 865 923 92617-year 866 849 877 868 858 827 865 91818-year 866 846 877 865 858 827 86019-year 866 846 877 864 858 82220-year 866 846 877 864 858

Table 2610Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 950 960 963 968 978 977 977 979 974 980 980 977 986 988 979 990 989 987 989 991 991 991 988 9912-year 939 953 957 966 974 975 977 976 974 977 980 977 985 987 979 990 985 987 988 991 991 988 9873-year 933 947 952 963 973 971 977 975 974 975 977 977 985 987 979 989 985 987 988 991 991 9884-year 931 944 950 961 973 965 975 971 972 975 977 977 985 987 979 989 983 986 987 991 9905-year 927 943 949 959 972 964 974 969 969 970 973 977 984 983 979 989 983 986 987 9906-year 923 942 947 955 972 961 973 965 965 970 973 976 983 981 979 989 983 986 9877-year 921 938 945 954 972 959 973 965 963 970 973 976 981 980 979 989 983 9858-year 917 937 945 954 972 959 973 965 962 966 973 976 980 980 979 987 9839-year 913 936 945 953 972 958 973 965 962 966 970 976 979 980 979 98710-year 912 934 942 949 972 957 973 965 960 964 970 976 977 980 97911-year 912 932 940 946 972 957 973 965 958 964 970 976 977 97912-year 911 931 940 945 972 955 973 965 952 964 970 976 97713-year 909 929 940 944 972 955 973 955 949 964 970 97614-year 908 928 939 943 972 955 973 949 946 964 97015-year 907 924 938 940 967 950 973 943 944 96416-year 906 923 937 939 958 950 973 942 94417-year 904 923 936 939 958 950 971 94118-year 899 923 935 938 958 950 96719-year 898 923 932 938 958 95020-year 898 923 932 938 958

Table 2611Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 002 011 122 006 Asian 0 000 002 010 128 011

10 002 011 029 123 006 Pacific 10 002 010 027 129 011

20 009 027 049 121 006 Islander 20 008 024 047 127 011

30 018 040 065 114 007 30 017 039 063 120 011

40 023 047 072 097 007 40 022 046 072 104 011

50 025 050 068 077 007 50 024 051 070 083 011

60 026 046 053 054 006 60 027 047 058 060 011

70 022 030 - 032 006 70 021 032 - 035 010

80 011 - - 013 005 80 013 - - 017 008

White 0 000 003 012 128 006 American 0 000 002 007 083 007

10 003 012 031 129 006 Indian 10 002 007 018 084 007

20 010 029 052 127 006 Alaska 20 005 016 026 083 007

30 019 043 069 118 006 Nativea 30 011 021 036 079 007

40 024 050 074 100 006 40 010 026 043 070 007

50 027 052 071 079 006 50 016 034 048 063 008

60 027 047 054 055 006 60 019 034 047 050 007

70 022 031 - 032 006 70 017 032 - 035 007

80 011 - - 013 005 80 020 - - 024 009

Black 0 000 001 004 074 006 Hispanicb 0 000 002 009 114 009

10 001 004 012 076 006 10 002 009 023 115 009

20 003 012 026 075 006 20 007 021 040 113 009

30 009 023 038 073 006 30 014 033 055 107 009

40 015 030 048 066 006 40 019 042 065 094 010

50 016 034 046 053 006 50 023 047 067 077 010

60 020 033 039 040 006 60 025 045 053 056 009

70 016 023 - 025 006 70 022 031 - 034 009

80 010 - - 013 005 80 011 - - 014 007

Table 2612

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 001 004 064 006 Asian 0 000 001 004 067 008

10 001 004 010 065 006 Pacific 10 001 004 010 067 008

20 003 009 019 064 006 Islander 20 003 009 020 066 008

30 007 016 029 062 006 30 007 017 028 064 008

40 010 022 038 056 006 40 010 021 036 058 008

50 013 029 042 048 006 50 011 026 039 048 008

60 017 031 037 038 006 60 016 029 038 038 008

70 016 023 - 024 005 70 015 024 - 025 007

80 010 - - 011 004 80 011 - - 012 006

White 0 000 001 004 068 006 American 0 000 001 003 034 006

10 001 004 011 069 006 Indian 10 001 003 006 035 006

20 003 010 020 068 006 Alaska 20 002 005 008 034 006

30 007 017 031 066 006 Nativea 30 003 006 010 033 006

40 010 024 040 060 006 40 002 007 015 030 006

50 014 031 045 051 006 50 005 013 022 030 007

60 018 033 039 039 006 60 009 019 027 027 007

70 017 024 - 025 005 70 011 020 - 021 007

80 010 - - 011 004 80 013 - - 014 008

Black 0 000 000 001 031 003 Hispanicb 0 000 001 003 050 007

10 000 001 004 031 004 10 001 003 007 050 007

20 001 003 008 031 004 20 002 006 012 050 007

30 003 007 014 031 004 30 004 011 020 048 007

40 004 012 020 029 004 40 006 016 028 045 007

50 008 016 023 026 004 50 010 022 033 039 007

60 010 017 021 021 004 60 013 025 030 031 007

70 010 014 - 014 003 70 013 019 - 020 006

80 007 - - 007 002 80 008 - - 010 005

Table 2613

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 004 019 181 007 Asian 0 000 003 016 183 013

10 004 018 048 182 007 Pacific 10 003 016 042 184 013

20 015 044 079 179 007 Islander 20 013 039 072 181 013

30 030 065 101 165 007 30 026 059 094 169 013

40 036 072 105 137 007 40 033 068 104 144 013

50 037 071 094 104 007 50 035 071 096 112 013

60 035 059 068 070 007 60 037 062 074 079 013

70 027 036 - 038 006 70 027 039 - 044 012

80 012 - - 015 005 80 015 - - 020 009

White 0 000 004 021 190 007 American 0 000 003 011 132 008

10 004 021 053 192 007 Indian 10 002 011 030 133 008

20 017 049 086 188 007 Alaska 20 009 027 044 131 008

30 032 070 108 172 007 Nativea 30 019 036 062 124 008

40 038 076 109 141 007 40 017 044 069 107 008

50 039 073 097 106 007 50 027 054 073 093 008

60 035 060 069 070 007 60 028 048 065 069 007

70 027 037 - 038 006 70 022 041 - 046 007

80 012 - - 014 005 80 024 - - 030 008

Black 0 000 001 007 114 008 Hispanicb 0 000 004 017 179 011

10 001 007 021 116 008 10 004 017 041 180 011

20 006 020 043 116 008 20 013 038 069 177 011

30 015 038 061 111 008 30 025 056 092 165 011

40 024 047 072 098 008 40 031 068 102 141 011

50 024 050 067 076 008 50 037 072 098 111 011

60 028 046 054 056 008 60 036 063 074 077 011

70 021 030 - 033 008 70 030 041 - 044 010

80 012 - - 016 006 80 014 - - 017 008

Table 2614

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

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1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

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1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

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1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

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1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 7: SEER Cancer Statistics Review 1975-2015

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a SEER 18 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2011-2015All ages 145 73 214 153 78 228 89 38 134Under 65 132 58 205 141 63 220 76 27 12065 and over 231 175 278 235 182 282 181 114 228

All ages (WHO world std)c 128 62 192 135 66 205 76 31 116

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 02 - 02 02 - 03 - - -10-14 09 05 14 11 05 16 - - -15-19 31 09 53 34 10 60 11 - 1820-24 62 20 107 71 23 124 17 - 3225-29 105 35 179 117 40 200 42 11 7230-34 160 57 264 175 63 291 67 16 11335-39 201 74 328 214 78 354 111 32 18240-44 220 91 347 230 97 367 146 48 23345-49 236 109 362 249 117 382 144 47 23150-54 256 123 385 270 133 407 152 59 23455-59 262 144 373 275 154 393 172 89 24360-64 260 163 348 267 174 355 203 91 29565-69 290 199 370 294 207 373 225 127 30070-74 259 195 313 268 204 323 195 131 24175-79 231 177 272 237 184 280 179 118 22080-84 174 157 186 175 161 186 129 106 14185+ 110 96 117 107 99 111 122 - 153

US MortalityAge at DeathAge-Adjusted Rates 2011-2015All ages 05 05 05 05 05 05 05 04 06Under 65 01 02 01 01 02 01 02 01 0265 and over 30 30 29 29 30 28 29 21 33

All ages (WHO world std)c 03 04 03 03 04 03 03 03 04

Age-Specific Rates 2011-2015lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 - - - - - - - - -25-29 00 - - 00 - - - - -30-34 00 00 - 00 - - - - -35-39 00 00 00 00 00 - - - -40-44 01 01 01 01 01 01 - - -45-49 02 03 02 02 03 01 03 03 0350-54 04 04 03 04 05 03 04 03 0555-59 06 07 06 06 07 05 05 04 0660-64 11 12 10 11 12 09 12 09 1465-69 16 17 15 16 17 14 16 14 1870-74 22 22 21 21 22 21 25 20 2875-79 31 32 31 31 33 30 30 28 3180-84 43 42 43 42 43 41 37 23 4585+ 57 54 59 57 56 57 54 26 66

Table 267Cancer of the Thyroid (Invasive)

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2015 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2015

d Period survival provides a 2014 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2008-2014 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 83 75 87 - - -1970-1973a - - - 86 82 87 - - -1975-1977b 921 911 925 918 907 922 898 - 9101978-1980b 921 872 936 915 875 927 902 680h 9551981-1983b 936 922 939 931 909 937 964 1000 9321984-1986b 932 898 943 932 894 944 893 855g 9031987-1989b 944 916 952 941 916 950 923 912g 9231990-1992b 943 905 955 949 916 960 859 845g 8631993-1995b 954 916 967 956 915 969 932 878g 9431996-1998b 956 910 969 959 913 973 951 865g 9661999-2001b 965 943 971 968 949 974 920 884g 9242002-2004b 973 939 982 974 941 983 959 942 9602005-2007b 979 961 985 980 961 986 963 915 9692008-2014b 983f 960f 989f 986f 965f 992f 970f 913 979f

5-Year Period Survival (Percent)cd

2014 982 958 989 984 961 990 969 928 974

Stage Distribution () 2008-2014ce

All StagesNumber of cases 74280 17072 57208 59623 14147 45476 5139 909 4230Percent 100 100 100 100 100 100 100 100 100Localized 67 58 70 67 58 70 80 72 81Regional 27 33 25 27 34 25 14 18 13Distant 4 7 3 4 6 3 4 8 4UnstagedUnknown 2 2 2 2 2 2 2 2 2

5-Year Relative Survival (Percent) 2008-2014c

Age at DiagnosisAges lt45 997 991 998 997 993 998 992 965 995Ages 45-54 988 962 995 988 964 995 990 959 995Ages 55-64 980 952 989 983 953 992 956 920 963Ages 65-74 963 917 974 966 923 977 939 822g 965Ages 75+ 863 847 867 884 863 888 754 728g 739Ages lt65 991 971 996 991 972 996 983 952 990Ages 65+ 932 896 943 942 905 949 889 824g 903

StageeAll Stages 981 956 988 983 958 990 972 929 977Localized 999 998 1000 999 998 1000 998 989 999Regional 980 964 987 982 966 989 944 896 958Distant 555 509 583 558 507 592 470 424g 487UnstagedUnknown 891 836 909 884 845 897 887 - 915

Table 268Cancer of the Thyroid (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 949 951 959 962 967 968 964 977 972 976 976 971 979 983 977 985 985 983 988 989 987 988 983 9872-year 935 945 952 957 961 966 962 971 971 970 974 971 979 979 973 984 981 982 987 986 986 984 9823-year 929 937 948 953 960 960 962 969 971 969 970 971 977 979 973 983 980 982 987 985 986 9844-year 925 934 943 950 959 954 956 963 970 969 970 971 974 977 973 983 979 980 987 984 9865-year 921 933 941 947 958 949 953 962 969 963 962 971 973 973 973 982 979 978 987 9816-year 916 931 938 943 958 948 952 958 964 963 962 967 970 972 973 982 979 978 9877-year 914 927 934 942 956 945 952 958 962 961 961 965 968 969 973 981 979 9788-year 911 926 933 941 955 942 951 958 960 959 959 963 967 968 973 980 9799-year 907 923 931 939 955 937 949 958 956 959 954 963 967 968 973 98010-year 905 920 928 936 951 936 949 958 954 958 954 963 967 967 97311-year 903 917 927 933 950 933 949 958 950 958 954 961 967 96512-year 903 914 926 930 950 930 949 958 948 958 954 959 96713-year 900 912 925 930 950 928 949 950 947 958 954 95914-year 899 912 924 927 950 926 949 946 946 958 95415-year 897 907 923 923 943 924 949 941 945 95816-year 896 906 923 922 938 924 949 938 94517-year 895 906 922 922 938 923 949 93718-year 893 905 922 921 938 923 94319-year 892 905 919 921 938 92320-year 892 905 919 921 938

Table 269Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 946 925 948 946 934 937 918 972 965 963 961 951 956 967 971 964 973 968 983 978 973 979 967 9712-year 925 920 937 932 919 934 909 954 962 949 955 949 953 951 956 961 965 961 982 963 969 972 9643-year 915 908 935 924 917 921 909 947 962 949 942 949 942 948 956 961 965 961 982 961 967 9684-year 905 904 921 919 914 917 895 937 962 949 936 946 935 943 956 961 965 957 982 956 9675-year 899 902 916 910 912 898 882 937 962 938 924 943 932 940 956 957 963 951 980 9436-year 896 898 911 906 903 898 880 935 958 938 920 938 917 940 956 957 963 951 9787-year 894 893 900 904 887 895 880 933 954 934 919 924 917 928 956 953 963 9498-year 893 893 896 901 887 885 878 933 952 934 911 915 917 925 953 953 9639-year 888 886 885 899 887 867 869 933 930 934 898 910 917 921 953 95310-year 883 879 885 897 874 864 869 933 926 934 896 910 917 915 94911-year 875 872 884 895 862 848 865 933 926 934 896 902 917 91512-year 875 864 883 887 860 841 865 931 926 934 893 899 91713-year 873 862 878 882 860 831 865 931 926 927 893 89914-year 873 862 877 878 858 827 865 931 926 927 89315-year 867 854 877 872 858 827 865 931 926 92416-year 866 853 877 868 858 827 865 923 92617-year 866 849 877 868 858 827 865 91818-year 866 846 877 865 858 827 86019-year 866 846 877 864 858 82220-year 866 846 877 864 858

Table 2610Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 950 960 963 968 978 977 977 979 974 980 980 977 986 988 979 990 989 987 989 991 991 991 988 9912-year 939 953 957 966 974 975 977 976 974 977 980 977 985 987 979 990 985 987 988 991 991 988 9873-year 933 947 952 963 973 971 977 975 974 975 977 977 985 987 979 989 985 987 988 991 991 9884-year 931 944 950 961 973 965 975 971 972 975 977 977 985 987 979 989 983 986 987 991 9905-year 927 943 949 959 972 964 974 969 969 970 973 977 984 983 979 989 983 986 987 9906-year 923 942 947 955 972 961 973 965 965 970 973 976 983 981 979 989 983 986 9877-year 921 938 945 954 972 959 973 965 963 970 973 976 981 980 979 989 983 9858-year 917 937 945 954 972 959 973 965 962 966 973 976 980 980 979 987 9839-year 913 936 945 953 972 958 973 965 962 966 970 976 979 980 979 98710-year 912 934 942 949 972 957 973 965 960 964 970 976 977 980 97911-year 912 932 940 946 972 957 973 965 958 964 970 976 977 97912-year 911 931 940 945 972 955 973 965 952 964 970 976 97713-year 909 929 940 944 972 955 973 955 949 964 970 97614-year 908 928 939 943 972 955 973 949 946 964 97015-year 907 924 938 940 967 950 973 943 944 96416-year 906 923 937 939 958 950 973 942 94417-year 904 923 936 939 958 950 971 94118-year 899 923 935 938 958 950 96719-year 898 923 932 938 958 95020-year 898 923 932 938 958

Table 2611Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 002 011 122 006 Asian 0 000 002 010 128 011

10 002 011 029 123 006 Pacific 10 002 010 027 129 011

20 009 027 049 121 006 Islander 20 008 024 047 127 011

30 018 040 065 114 007 30 017 039 063 120 011

40 023 047 072 097 007 40 022 046 072 104 011

50 025 050 068 077 007 50 024 051 070 083 011

60 026 046 053 054 006 60 027 047 058 060 011

70 022 030 - 032 006 70 021 032 - 035 010

80 011 - - 013 005 80 013 - - 017 008

White 0 000 003 012 128 006 American 0 000 002 007 083 007

10 003 012 031 129 006 Indian 10 002 007 018 084 007

20 010 029 052 127 006 Alaska 20 005 016 026 083 007

30 019 043 069 118 006 Nativea 30 011 021 036 079 007

40 024 050 074 100 006 40 010 026 043 070 007

50 027 052 071 079 006 50 016 034 048 063 008

60 027 047 054 055 006 60 019 034 047 050 007

70 022 031 - 032 006 70 017 032 - 035 007

80 011 - - 013 005 80 020 - - 024 009

Black 0 000 001 004 074 006 Hispanicb 0 000 002 009 114 009

10 001 004 012 076 006 10 002 009 023 115 009

20 003 012 026 075 006 20 007 021 040 113 009

30 009 023 038 073 006 30 014 033 055 107 009

40 015 030 048 066 006 40 019 042 065 094 010

50 016 034 046 053 006 50 023 047 067 077 010

60 020 033 039 040 006 60 025 045 053 056 009

70 016 023 - 025 006 70 022 031 - 034 009

80 010 - - 013 005 80 011 - - 014 007

Table 2612

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 001 004 064 006 Asian 0 000 001 004 067 008

10 001 004 010 065 006 Pacific 10 001 004 010 067 008

20 003 009 019 064 006 Islander 20 003 009 020 066 008

30 007 016 029 062 006 30 007 017 028 064 008

40 010 022 038 056 006 40 010 021 036 058 008

50 013 029 042 048 006 50 011 026 039 048 008

60 017 031 037 038 006 60 016 029 038 038 008

70 016 023 - 024 005 70 015 024 - 025 007

80 010 - - 011 004 80 011 - - 012 006

White 0 000 001 004 068 006 American 0 000 001 003 034 006

10 001 004 011 069 006 Indian 10 001 003 006 035 006

20 003 010 020 068 006 Alaska 20 002 005 008 034 006

30 007 017 031 066 006 Nativea 30 003 006 010 033 006

40 010 024 040 060 006 40 002 007 015 030 006

50 014 031 045 051 006 50 005 013 022 030 007

60 018 033 039 039 006 60 009 019 027 027 007

70 017 024 - 025 005 70 011 020 - 021 007

80 010 - - 011 004 80 013 - - 014 008

Black 0 000 000 001 031 003 Hispanicb 0 000 001 003 050 007

10 000 001 004 031 004 10 001 003 007 050 007

20 001 003 008 031 004 20 002 006 012 050 007

30 003 007 014 031 004 30 004 011 020 048 007

40 004 012 020 029 004 40 006 016 028 045 007

50 008 016 023 026 004 50 010 022 033 039 007

60 010 017 021 021 004 60 013 025 030 031 007

70 010 014 - 014 003 70 013 019 - 020 006

80 007 - - 007 002 80 008 - - 010 005

Table 2613

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 004 019 181 007 Asian 0 000 003 016 183 013

10 004 018 048 182 007 Pacific 10 003 016 042 184 013

20 015 044 079 179 007 Islander 20 013 039 072 181 013

30 030 065 101 165 007 30 026 059 094 169 013

40 036 072 105 137 007 40 033 068 104 144 013

50 037 071 094 104 007 50 035 071 096 112 013

60 035 059 068 070 007 60 037 062 074 079 013

70 027 036 - 038 006 70 027 039 - 044 012

80 012 - - 015 005 80 015 - - 020 009

White 0 000 004 021 190 007 American 0 000 003 011 132 008

10 004 021 053 192 007 Indian 10 002 011 030 133 008

20 017 049 086 188 007 Alaska 20 009 027 044 131 008

30 032 070 108 172 007 Nativea 30 019 036 062 124 008

40 038 076 109 141 007 40 017 044 069 107 008

50 039 073 097 106 007 50 027 054 073 093 008

60 035 060 069 070 007 60 028 048 065 069 007

70 027 037 - 038 006 70 022 041 - 046 007

80 012 - - 014 005 80 024 - - 030 008

Black 0 000 001 007 114 008 Hispanicb 0 000 004 017 179 011

10 001 007 021 116 008 10 004 017 041 180 011

20 006 020 043 116 008 20 013 038 069 177 011

30 015 038 061 111 008 30 025 056 092 165 011

40 024 047 072 098 008 40 031 068 102 141 011

50 024 050 067 076 008 50 037 072 098 111 011

60 028 046 054 056 008 60 036 063 074 077 011

70 021 030 - 033 008 70 030 041 - 044 010

80 012 - - 016 006 80 014 - - 017 008

Table 2614

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

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Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 8: SEER Cancer Statistics Review 1975-2015

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1975-2015N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2015 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2015

d Period survival provides a 2014 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2008-2014 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 83 75 87 - - -1970-1973a - - - 86 82 87 - - -1975-1977b 921 911 925 918 907 922 898 - 9101978-1980b 921 872 936 915 875 927 902 680h 9551981-1983b 936 922 939 931 909 937 964 1000 9321984-1986b 932 898 943 932 894 944 893 855g 9031987-1989b 944 916 952 941 916 950 923 912g 9231990-1992b 943 905 955 949 916 960 859 845g 8631993-1995b 954 916 967 956 915 969 932 878g 9431996-1998b 956 910 969 959 913 973 951 865g 9661999-2001b 965 943 971 968 949 974 920 884g 9242002-2004b 973 939 982 974 941 983 959 942 9602005-2007b 979 961 985 980 961 986 963 915 9692008-2014b 983f 960f 989f 986f 965f 992f 970f 913 979f

5-Year Period Survival (Percent)cd

2014 982 958 989 984 961 990 969 928 974

Stage Distribution () 2008-2014ce

All StagesNumber of cases 74280 17072 57208 59623 14147 45476 5139 909 4230Percent 100 100 100 100 100 100 100 100 100Localized 67 58 70 67 58 70 80 72 81Regional 27 33 25 27 34 25 14 18 13Distant 4 7 3 4 6 3 4 8 4UnstagedUnknown 2 2 2 2 2 2 2 2 2

5-Year Relative Survival (Percent) 2008-2014c

Age at DiagnosisAges lt45 997 991 998 997 993 998 992 965 995Ages 45-54 988 962 995 988 964 995 990 959 995Ages 55-64 980 952 989 983 953 992 956 920 963Ages 65-74 963 917 974 966 923 977 939 822g 965Ages 75+ 863 847 867 884 863 888 754 728g 739Ages lt65 991 971 996 991 972 996 983 952 990Ages 65+ 932 896 943 942 905 949 889 824g 903

StageeAll Stages 981 956 988 983 958 990 972 929 977Localized 999 998 1000 999 998 1000 998 989 999Regional 980 964 987 982 966 989 944 896 958Distant 555 509 583 558 507 592 470 424g 487UnstagedUnknown 891 836 909 884 845 897 887 - 915

Table 268Cancer of the Thyroid (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 949 951 959 962 967 968 964 977 972 976 976 971 979 983 977 985 985 983 988 989 987 988 983 9872-year 935 945 952 957 961 966 962 971 971 970 974 971 979 979 973 984 981 982 987 986 986 984 9823-year 929 937 948 953 960 960 962 969 971 969 970 971 977 979 973 983 980 982 987 985 986 9844-year 925 934 943 950 959 954 956 963 970 969 970 971 974 977 973 983 979 980 987 984 9865-year 921 933 941 947 958 949 953 962 969 963 962 971 973 973 973 982 979 978 987 9816-year 916 931 938 943 958 948 952 958 964 963 962 967 970 972 973 982 979 978 9877-year 914 927 934 942 956 945 952 958 962 961 961 965 968 969 973 981 979 9788-year 911 926 933 941 955 942 951 958 960 959 959 963 967 968 973 980 9799-year 907 923 931 939 955 937 949 958 956 959 954 963 967 968 973 98010-year 905 920 928 936 951 936 949 958 954 958 954 963 967 967 97311-year 903 917 927 933 950 933 949 958 950 958 954 961 967 96512-year 903 914 926 930 950 930 949 958 948 958 954 959 96713-year 900 912 925 930 950 928 949 950 947 958 954 95914-year 899 912 924 927 950 926 949 946 946 958 95415-year 897 907 923 923 943 924 949 941 945 95816-year 896 906 923 922 938 924 949 938 94517-year 895 906 922 922 938 923 949 93718-year 893 905 922 921 938 923 94319-year 892 905 919 921 938 92320-year 892 905 919 921 938

Table 269Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 946 925 948 946 934 937 918 972 965 963 961 951 956 967 971 964 973 968 983 978 973 979 967 9712-year 925 920 937 932 919 934 909 954 962 949 955 949 953 951 956 961 965 961 982 963 969 972 9643-year 915 908 935 924 917 921 909 947 962 949 942 949 942 948 956 961 965 961 982 961 967 9684-year 905 904 921 919 914 917 895 937 962 949 936 946 935 943 956 961 965 957 982 956 9675-year 899 902 916 910 912 898 882 937 962 938 924 943 932 940 956 957 963 951 980 9436-year 896 898 911 906 903 898 880 935 958 938 920 938 917 940 956 957 963 951 9787-year 894 893 900 904 887 895 880 933 954 934 919 924 917 928 956 953 963 9498-year 893 893 896 901 887 885 878 933 952 934 911 915 917 925 953 953 9639-year 888 886 885 899 887 867 869 933 930 934 898 910 917 921 953 95310-year 883 879 885 897 874 864 869 933 926 934 896 910 917 915 94911-year 875 872 884 895 862 848 865 933 926 934 896 902 917 91512-year 875 864 883 887 860 841 865 931 926 934 893 899 91713-year 873 862 878 882 860 831 865 931 926 927 893 89914-year 873 862 877 878 858 827 865 931 926 927 89315-year 867 854 877 872 858 827 865 931 926 92416-year 866 853 877 868 858 827 865 923 92617-year 866 849 877 868 858 827 865 91818-year 866 846 877 865 858 827 86019-year 866 846 877 864 858 82220-year 866 846 877 864 858

Table 2610Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 950 960 963 968 978 977 977 979 974 980 980 977 986 988 979 990 989 987 989 991 991 991 988 9912-year 939 953 957 966 974 975 977 976 974 977 980 977 985 987 979 990 985 987 988 991 991 988 9873-year 933 947 952 963 973 971 977 975 974 975 977 977 985 987 979 989 985 987 988 991 991 9884-year 931 944 950 961 973 965 975 971 972 975 977 977 985 987 979 989 983 986 987 991 9905-year 927 943 949 959 972 964 974 969 969 970 973 977 984 983 979 989 983 986 987 9906-year 923 942 947 955 972 961 973 965 965 970 973 976 983 981 979 989 983 986 9877-year 921 938 945 954 972 959 973 965 963 970 973 976 981 980 979 989 983 9858-year 917 937 945 954 972 959 973 965 962 966 973 976 980 980 979 987 9839-year 913 936 945 953 972 958 973 965 962 966 970 976 979 980 979 98710-year 912 934 942 949 972 957 973 965 960 964 970 976 977 980 97911-year 912 932 940 946 972 957 973 965 958 964 970 976 977 97912-year 911 931 940 945 972 955 973 965 952 964 970 976 97713-year 909 929 940 944 972 955 973 955 949 964 970 97614-year 908 928 939 943 972 955 973 949 946 964 97015-year 907 924 938 940 967 950 973 943 944 96416-year 906 923 937 939 958 950 973 942 94417-year 904 923 936 939 958 950 971 94118-year 899 923 935 938 958 950 96719-year 898 923 932 938 958 95020-year 898 923 932 938 958

Table 2611Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 002 011 122 006 Asian 0 000 002 010 128 011

10 002 011 029 123 006 Pacific 10 002 010 027 129 011

20 009 027 049 121 006 Islander 20 008 024 047 127 011

30 018 040 065 114 007 30 017 039 063 120 011

40 023 047 072 097 007 40 022 046 072 104 011

50 025 050 068 077 007 50 024 051 070 083 011

60 026 046 053 054 006 60 027 047 058 060 011

70 022 030 - 032 006 70 021 032 - 035 010

80 011 - - 013 005 80 013 - - 017 008

White 0 000 003 012 128 006 American 0 000 002 007 083 007

10 003 012 031 129 006 Indian 10 002 007 018 084 007

20 010 029 052 127 006 Alaska 20 005 016 026 083 007

30 019 043 069 118 006 Nativea 30 011 021 036 079 007

40 024 050 074 100 006 40 010 026 043 070 007

50 027 052 071 079 006 50 016 034 048 063 008

60 027 047 054 055 006 60 019 034 047 050 007

70 022 031 - 032 006 70 017 032 - 035 007

80 011 - - 013 005 80 020 - - 024 009

Black 0 000 001 004 074 006 Hispanicb 0 000 002 009 114 009

10 001 004 012 076 006 10 002 009 023 115 009

20 003 012 026 075 006 20 007 021 040 113 009

30 009 023 038 073 006 30 014 033 055 107 009

40 015 030 048 066 006 40 019 042 065 094 010

50 016 034 046 053 006 50 023 047 067 077 010

60 020 033 039 040 006 60 025 045 053 056 009

70 016 023 - 025 006 70 022 031 - 034 009

80 010 - - 013 005 80 011 - - 014 007

Table 2612

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 001 004 064 006 Asian 0 000 001 004 067 008

10 001 004 010 065 006 Pacific 10 001 004 010 067 008

20 003 009 019 064 006 Islander 20 003 009 020 066 008

30 007 016 029 062 006 30 007 017 028 064 008

40 010 022 038 056 006 40 010 021 036 058 008

50 013 029 042 048 006 50 011 026 039 048 008

60 017 031 037 038 006 60 016 029 038 038 008

70 016 023 - 024 005 70 015 024 - 025 007

80 010 - - 011 004 80 011 - - 012 006

White 0 000 001 004 068 006 American 0 000 001 003 034 006

10 001 004 011 069 006 Indian 10 001 003 006 035 006

20 003 010 020 068 006 Alaska 20 002 005 008 034 006

30 007 017 031 066 006 Nativea 30 003 006 010 033 006

40 010 024 040 060 006 40 002 007 015 030 006

50 014 031 045 051 006 50 005 013 022 030 007

60 018 033 039 039 006 60 009 019 027 027 007

70 017 024 - 025 005 70 011 020 - 021 007

80 010 - - 011 004 80 013 - - 014 008

Black 0 000 000 001 031 003 Hispanicb 0 000 001 003 050 007

10 000 001 004 031 004 10 001 003 007 050 007

20 001 003 008 031 004 20 002 006 012 050 007

30 003 007 014 031 004 30 004 011 020 048 007

40 004 012 020 029 004 40 006 016 028 045 007

50 008 016 023 026 004 50 010 022 033 039 007

60 010 017 021 021 004 60 013 025 030 031 007

70 010 014 - 014 003 70 013 019 - 020 006

80 007 - - 007 002 80 008 - - 010 005

Table 2613

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 004 019 181 007 Asian 0 000 003 016 183 013

10 004 018 048 182 007 Pacific 10 003 016 042 184 013

20 015 044 079 179 007 Islander 20 013 039 072 181 013

30 030 065 101 165 007 30 026 059 094 169 013

40 036 072 105 137 007 40 033 068 104 144 013

50 037 071 094 104 007 50 035 071 096 112 013

60 035 059 068 070 007 60 037 062 074 079 013

70 027 036 - 038 006 70 027 039 - 044 012

80 012 - - 015 005 80 015 - - 020 009

White 0 000 004 021 190 007 American 0 000 003 011 132 008

10 004 021 053 192 007 Indian 10 002 011 030 133 008

20 017 049 086 188 007 Alaska 20 009 027 044 131 008

30 032 070 108 172 007 Nativea 30 019 036 062 124 008

40 038 076 109 141 007 40 017 044 069 107 008

50 039 073 097 106 007 50 027 054 073 093 008

60 035 060 069 070 007 60 028 048 065 069 007

70 027 037 - 038 006 70 022 041 - 046 007

80 012 - - 014 005 80 024 - - 030 008

Black 0 000 001 007 114 008 Hispanicb 0 000 004 017 179 011

10 001 007 021 116 008 10 004 017 041 180 011

20 006 020 043 116 008 20 013 038 069 177 011

30 015 038 061 111 008 30 025 056 092 165 011

40 024 047 072 098 008 40 031 068 102 141 011

50 024 050 067 076 008 50 037 072 098 111 011

60 028 046 054 056 008 60 036 063 074 077 011

70 021 030 - 033 008 70 030 041 - 044 010

80 012 - - 016 006 80 014 - - 017 008

Table 2614

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 9: SEER Cancer Statistics Review 1975-2015

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 949 951 959 962 967 968 964 977 972 976 976 971 979 983 977 985 985 983 988 989 987 988 983 9872-year 935 945 952 957 961 966 962 971 971 970 974 971 979 979 973 984 981 982 987 986 986 984 9823-year 929 937 948 953 960 960 962 969 971 969 970 971 977 979 973 983 980 982 987 985 986 9844-year 925 934 943 950 959 954 956 963 970 969 970 971 974 977 973 983 979 980 987 984 9865-year 921 933 941 947 958 949 953 962 969 963 962 971 973 973 973 982 979 978 987 9816-year 916 931 938 943 958 948 952 958 964 963 962 967 970 972 973 982 979 978 9877-year 914 927 934 942 956 945 952 958 962 961 961 965 968 969 973 981 979 9788-year 911 926 933 941 955 942 951 958 960 959 959 963 967 968 973 980 9799-year 907 923 931 939 955 937 949 958 956 959 954 963 967 968 973 98010-year 905 920 928 936 951 936 949 958 954 958 954 963 967 967 97311-year 903 917 927 933 950 933 949 958 950 958 954 961 967 96512-year 903 914 926 930 950 930 949 958 948 958 954 959 96713-year 900 912 925 930 950 928 949 950 947 958 954 95914-year 899 912 924 927 950 926 949 946 946 958 95415-year 897 907 923 923 943 924 949 941 945 95816-year 896 906 923 922 938 924 949 938 94517-year 895 906 922 922 938 923 949 93718-year 893 905 922 921 938 923 94319-year 892 905 919 921 938 92320-year 892 905 919 921 938

Table 269Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 946 925 948 946 934 937 918 972 965 963 961 951 956 967 971 964 973 968 983 978 973 979 967 9712-year 925 920 937 932 919 934 909 954 962 949 955 949 953 951 956 961 965 961 982 963 969 972 9643-year 915 908 935 924 917 921 909 947 962 949 942 949 942 948 956 961 965 961 982 961 967 9684-year 905 904 921 919 914 917 895 937 962 949 936 946 935 943 956 961 965 957 982 956 9675-year 899 902 916 910 912 898 882 937 962 938 924 943 932 940 956 957 963 951 980 9436-year 896 898 911 906 903 898 880 935 958 938 920 938 917 940 956 957 963 951 9787-year 894 893 900 904 887 895 880 933 954 934 919 924 917 928 956 953 963 9498-year 893 893 896 901 887 885 878 933 952 934 911 915 917 925 953 953 9639-year 888 886 885 899 887 867 869 933 930 934 898 910 917 921 953 95310-year 883 879 885 897 874 864 869 933 926 934 896 910 917 915 94911-year 875 872 884 895 862 848 865 933 926 934 896 902 917 91512-year 875 864 883 887 860 841 865 931 926 934 893 899 91713-year 873 862 878 882 860 831 865 931 926 927 893 89914-year 873 862 877 878 858 827 865 931 926 927 89315-year 867 854 877 872 858 827 865 931 926 92416-year 866 853 877 868 858 827 865 923 92617-year 866 849 877 868 858 827 865 91818-year 866 846 877 865 858 827 86019-year 866 846 877 864 858 82220-year 866 846 877 864 858

Table 2610Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 950 960 963 968 978 977 977 979 974 980 980 977 986 988 979 990 989 987 989 991 991 991 988 9912-year 939 953 957 966 974 975 977 976 974 977 980 977 985 987 979 990 985 987 988 991 991 988 9873-year 933 947 952 963 973 971 977 975 974 975 977 977 985 987 979 989 985 987 988 991 991 9884-year 931 944 950 961 973 965 975 971 972 975 977 977 985 987 979 989 983 986 987 991 9905-year 927 943 949 959 972 964 974 969 969 970 973 977 984 983 979 989 983 986 987 9906-year 923 942 947 955 972 961 973 965 965 970 973 976 983 981 979 989 983 986 9877-year 921 938 945 954 972 959 973 965 963 970 973 976 981 980 979 989 983 9858-year 917 937 945 954 972 959 973 965 962 966 973 976 980 980 979 987 9839-year 913 936 945 953 972 958 973 965 962 966 970 976 979 980 979 98710-year 912 934 942 949 972 957 973 965 960 964 970 976 977 980 97911-year 912 932 940 946 972 957 973 965 958 964 970 976 977 97912-year 911 931 940 945 972 955 973 965 952 964 970 976 97713-year 909 929 940 944 972 955 973 955 949 964 970 97614-year 908 928 939 943 972 955 973 949 946 964 97015-year 907 924 938 940 967 950 973 943 944 96416-year 906 923 937 939 958 950 973 942 94417-year 904 923 936 939 958 950 971 94118-year 899 923 935 938 958 950 96719-year 898 923 932 938 958 95020-year 898 923 932 938 958

Table 2611Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 002 011 122 006 Asian 0 000 002 010 128 011

10 002 011 029 123 006 Pacific 10 002 010 027 129 011

20 009 027 049 121 006 Islander 20 008 024 047 127 011

30 018 040 065 114 007 30 017 039 063 120 011

40 023 047 072 097 007 40 022 046 072 104 011

50 025 050 068 077 007 50 024 051 070 083 011

60 026 046 053 054 006 60 027 047 058 060 011

70 022 030 - 032 006 70 021 032 - 035 010

80 011 - - 013 005 80 013 - - 017 008

White 0 000 003 012 128 006 American 0 000 002 007 083 007

10 003 012 031 129 006 Indian 10 002 007 018 084 007

20 010 029 052 127 006 Alaska 20 005 016 026 083 007

30 019 043 069 118 006 Nativea 30 011 021 036 079 007

40 024 050 074 100 006 40 010 026 043 070 007

50 027 052 071 079 006 50 016 034 048 063 008

60 027 047 054 055 006 60 019 034 047 050 007

70 022 031 - 032 006 70 017 032 - 035 007

80 011 - - 013 005 80 020 - - 024 009

Black 0 000 001 004 074 006 Hispanicb 0 000 002 009 114 009

10 001 004 012 076 006 10 002 009 023 115 009

20 003 012 026 075 006 20 007 021 040 113 009

30 009 023 038 073 006 30 014 033 055 107 009

40 015 030 048 066 006 40 019 042 065 094 010

50 016 034 046 053 006 50 023 047 067 077 010

60 020 033 039 040 006 60 025 045 053 056 009

70 016 023 - 025 006 70 022 031 - 034 009

80 010 - - 013 005 80 011 - - 014 007

Table 2612

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 001 004 064 006 Asian 0 000 001 004 067 008

10 001 004 010 065 006 Pacific 10 001 004 010 067 008

20 003 009 019 064 006 Islander 20 003 009 020 066 008

30 007 016 029 062 006 30 007 017 028 064 008

40 010 022 038 056 006 40 010 021 036 058 008

50 013 029 042 048 006 50 011 026 039 048 008

60 017 031 037 038 006 60 016 029 038 038 008

70 016 023 - 024 005 70 015 024 - 025 007

80 010 - - 011 004 80 011 - - 012 006

White 0 000 001 004 068 006 American 0 000 001 003 034 006

10 001 004 011 069 006 Indian 10 001 003 006 035 006

20 003 010 020 068 006 Alaska 20 002 005 008 034 006

30 007 017 031 066 006 Nativea 30 003 006 010 033 006

40 010 024 040 060 006 40 002 007 015 030 006

50 014 031 045 051 006 50 005 013 022 030 007

60 018 033 039 039 006 60 009 019 027 027 007

70 017 024 - 025 005 70 011 020 - 021 007

80 010 - - 011 004 80 013 - - 014 008

Black 0 000 000 001 031 003 Hispanicb 0 000 001 003 050 007

10 000 001 004 031 004 10 001 003 007 050 007

20 001 003 008 031 004 20 002 006 012 050 007

30 003 007 014 031 004 30 004 011 020 048 007

40 004 012 020 029 004 40 006 016 028 045 007

50 008 016 023 026 004 50 010 022 033 039 007

60 010 017 021 021 004 60 013 025 030 031 007

70 010 014 - 014 003 70 013 019 - 020 006

80 007 - - 007 002 80 008 - - 010 005

Table 2613

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 004 019 181 007 Asian 0 000 003 016 183 013

10 004 018 048 182 007 Pacific 10 003 016 042 184 013

20 015 044 079 179 007 Islander 20 013 039 072 181 013

30 030 065 101 165 007 30 026 059 094 169 013

40 036 072 105 137 007 40 033 068 104 144 013

50 037 071 094 104 007 50 035 071 096 112 013

60 035 059 068 070 007 60 037 062 074 079 013

70 027 036 - 038 006 70 027 039 - 044 012

80 012 - - 015 005 80 015 - - 020 009

White 0 000 004 021 190 007 American 0 000 003 011 132 008

10 004 021 053 192 007 Indian 10 002 011 030 133 008

20 017 049 086 188 007 Alaska 20 009 027 044 131 008

30 032 070 108 172 007 Nativea 30 019 036 062 124 008

40 038 076 109 141 007 40 017 044 069 107 008

50 039 073 097 106 007 50 027 054 073 093 008

60 035 060 069 070 007 60 028 048 065 069 007

70 027 037 - 038 006 70 022 041 - 046 007

80 012 - - 014 005 80 024 - - 030 008

Black 0 000 001 007 114 008 Hispanicb 0 000 004 017 179 011

10 001 007 021 116 008 10 004 017 041 180 011

20 006 020 043 116 008 20 013 038 069 177 011

30 015 038 061 111 008 30 025 056 092 165 011

40 024 047 072 098 008 40 031 068 102 141 011

50 024 050 067 076 008 50 037 072 098 111 011

60 028 046 054 056 008 60 036 063 074 077 011

70 021 030 - 033 008 70 030 041 - 044 010

80 012 - - 016 006 80 014 - - 017 008

Table 2614

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

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1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

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1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

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1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

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1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 10: SEER Cancer Statistics Review 1975-2015

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 946 925 948 946 934 937 918 972 965 963 961 951 956 967 971 964 973 968 983 978 973 979 967 9712-year 925 920 937 932 919 934 909 954 962 949 955 949 953 951 956 961 965 961 982 963 969 972 9643-year 915 908 935 924 917 921 909 947 962 949 942 949 942 948 956 961 965 961 982 961 967 9684-year 905 904 921 919 914 917 895 937 962 949 936 946 935 943 956 961 965 957 982 956 9675-year 899 902 916 910 912 898 882 937 962 938 924 943 932 940 956 957 963 951 980 9436-year 896 898 911 906 903 898 880 935 958 938 920 938 917 940 956 957 963 951 9787-year 894 893 900 904 887 895 880 933 954 934 919 924 917 928 956 953 963 9498-year 893 893 896 901 887 885 878 933 952 934 911 915 917 925 953 953 9639-year 888 886 885 899 887 867 869 933 930 934 898 910 917 921 953 95310-year 883 879 885 897 874 864 869 933 926 934 896 910 917 915 94911-year 875 872 884 895 862 848 865 933 926 934 896 902 917 91512-year 875 864 883 887 860 841 865 931 926 934 893 899 91713-year 873 862 878 882 860 831 865 931 926 927 893 89914-year 873 862 877 878 858 827 865 931 926 927 89315-year 867 854 877 872 858 827 865 931 926 92416-year 866 853 877 868 858 827 865 923 92617-year 866 849 877 868 858 827 865 91818-year 866 846 877 865 858 827 86019-year 866 846 877 864 858 82220-year 866 846 877 864 858

Table 2610Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 950 960 963 968 978 977 977 979 974 980 980 977 986 988 979 990 989 987 989 991 991 991 988 9912-year 939 953 957 966 974 975 977 976 974 977 980 977 985 987 979 990 985 987 988 991 991 988 9873-year 933 947 952 963 973 971 977 975 974 975 977 977 985 987 979 989 985 987 988 991 991 9884-year 931 944 950 961 973 965 975 971 972 975 977 977 985 987 979 989 983 986 987 991 9905-year 927 943 949 959 972 964 974 969 969 970 973 977 984 983 979 989 983 986 987 9906-year 923 942 947 955 972 961 973 965 965 970 973 976 983 981 979 989 983 986 9877-year 921 938 945 954 972 959 973 965 963 970 973 976 981 980 979 989 983 9858-year 917 937 945 954 972 959 973 965 962 966 973 976 980 980 979 987 9839-year 913 936 945 953 972 958 973 965 962 966 970 976 979 980 979 98710-year 912 934 942 949 972 957 973 965 960 964 970 976 977 980 97911-year 912 932 940 946 972 957 973 965 958 964 970 976 977 97912-year 911 931 940 945 972 955 973 965 952 964 970 976 97713-year 909 929 940 944 972 955 973 955 949 964 970 97614-year 908 928 939 943 972 955 973 949 946 964 97015-year 907 924 938 940 967 950 973 943 944 96416-year 906 923 937 939 958 950 973 942 94417-year 904 923 936 939 958 950 971 94118-year 899 923 935 938 958 950 96719-year 898 923 932 938 958 95020-year 898 923 932 938 958

Table 2611Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 002 011 122 006 Asian 0 000 002 010 128 011

10 002 011 029 123 006 Pacific 10 002 010 027 129 011

20 009 027 049 121 006 Islander 20 008 024 047 127 011

30 018 040 065 114 007 30 017 039 063 120 011

40 023 047 072 097 007 40 022 046 072 104 011

50 025 050 068 077 007 50 024 051 070 083 011

60 026 046 053 054 006 60 027 047 058 060 011

70 022 030 - 032 006 70 021 032 - 035 010

80 011 - - 013 005 80 013 - - 017 008

White 0 000 003 012 128 006 American 0 000 002 007 083 007

10 003 012 031 129 006 Indian 10 002 007 018 084 007

20 010 029 052 127 006 Alaska 20 005 016 026 083 007

30 019 043 069 118 006 Nativea 30 011 021 036 079 007

40 024 050 074 100 006 40 010 026 043 070 007

50 027 052 071 079 006 50 016 034 048 063 008

60 027 047 054 055 006 60 019 034 047 050 007

70 022 031 - 032 006 70 017 032 - 035 007

80 011 - - 013 005 80 020 - - 024 009

Black 0 000 001 004 074 006 Hispanicb 0 000 002 009 114 009

10 001 004 012 076 006 10 002 009 023 115 009

20 003 012 026 075 006 20 007 021 040 113 009

30 009 023 038 073 006 30 014 033 055 107 009

40 015 030 048 066 006 40 019 042 065 094 010

50 016 034 046 053 006 50 023 047 067 077 010

60 020 033 039 040 006 60 025 045 053 056 009

70 016 023 - 025 006 70 022 031 - 034 009

80 010 - - 013 005 80 011 - - 014 007

Table 2612

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 001 004 064 006 Asian 0 000 001 004 067 008

10 001 004 010 065 006 Pacific 10 001 004 010 067 008

20 003 009 019 064 006 Islander 20 003 009 020 066 008

30 007 016 029 062 006 30 007 017 028 064 008

40 010 022 038 056 006 40 010 021 036 058 008

50 013 029 042 048 006 50 011 026 039 048 008

60 017 031 037 038 006 60 016 029 038 038 008

70 016 023 - 024 005 70 015 024 - 025 007

80 010 - - 011 004 80 011 - - 012 006

White 0 000 001 004 068 006 American 0 000 001 003 034 006

10 001 004 011 069 006 Indian 10 001 003 006 035 006

20 003 010 020 068 006 Alaska 20 002 005 008 034 006

30 007 017 031 066 006 Nativea 30 003 006 010 033 006

40 010 024 040 060 006 40 002 007 015 030 006

50 014 031 045 051 006 50 005 013 022 030 007

60 018 033 039 039 006 60 009 019 027 027 007

70 017 024 - 025 005 70 011 020 - 021 007

80 010 - - 011 004 80 013 - - 014 008

Black 0 000 000 001 031 003 Hispanicb 0 000 001 003 050 007

10 000 001 004 031 004 10 001 003 007 050 007

20 001 003 008 031 004 20 002 006 012 050 007

30 003 007 014 031 004 30 004 011 020 048 007

40 004 012 020 029 004 40 006 016 028 045 007

50 008 016 023 026 004 50 010 022 033 039 007

60 010 017 021 021 004 60 013 025 030 031 007

70 010 014 - 014 003 70 013 019 - 020 006

80 007 - - 007 002 80 008 - - 010 005

Table 2613

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 004 019 181 007 Asian 0 000 003 016 183 013

10 004 018 048 182 007 Pacific 10 003 016 042 184 013

20 015 044 079 179 007 Islander 20 013 039 072 181 013

30 030 065 101 165 007 30 026 059 094 169 013

40 036 072 105 137 007 40 033 068 104 144 013

50 037 071 094 104 007 50 035 071 096 112 013

60 035 059 068 070 007 60 037 062 074 079 013

70 027 036 - 038 006 70 027 039 - 044 012

80 012 - - 015 005 80 015 - - 020 009

White 0 000 004 021 190 007 American 0 000 003 011 132 008

10 004 021 053 192 007 Indian 10 002 011 030 133 008

20 017 049 086 188 007 Alaska 20 009 027 044 131 008

30 032 070 108 172 007 Nativea 30 019 036 062 124 008

40 038 076 109 141 007 40 017 044 069 107 008

50 039 073 097 106 007 50 027 054 073 093 008

60 035 060 069 070 007 60 028 048 065 069 007

70 027 037 - 038 006 70 022 041 - 046 007

80 012 - - 014 005 80 024 - - 030 008

Black 0 000 001 007 114 008 Hispanicb 0 000 004 017 179 011

10 001 007 021 116 008 10 004 017 041 180 011

20 006 020 043 116 008 20 013 038 069 177 011

30 015 038 061 111 008 30 025 056 092 165 011

40 024 047 072 098 008 40 031 068 102 141 011

50 024 050 067 076 008 50 037 072 098 111 011

60 028 046 054 056 008 60 036 063 074 077 011

70 021 030 - 033 008 70 030 041 - 044 010

80 012 - - 016 006 80 014 - - 017 008

Table 2614

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

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ancer Statistics Review

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ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 11: SEER Cancer Statistics Review 1975-2015

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1975-2015N

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a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

Survival Time

1-year 950 960 963 968 978 977 977 979 974 980 980 977 986 988 979 990 989 987 989 991 991 991 988 9912-year 939 953 957 966 974 975 977 976 974 977 980 977 985 987 979 990 985 987 988 991 991 988 9873-year 933 947 952 963 973 971 977 975 974 975 977 977 985 987 979 989 985 987 988 991 991 9884-year 931 944 950 961 973 965 975 971 972 975 977 977 985 987 979 989 983 986 987 991 9905-year 927 943 949 959 972 964 974 969 969 970 973 977 984 983 979 989 983 986 987 9906-year 923 942 947 955 972 961 973 965 965 970 973 976 983 981 979 989 983 986 9877-year 921 938 945 954 972 959 973 965 963 970 973 976 981 980 979 989 983 9858-year 917 937 945 954 972 959 973 965 962 966 973 976 980 980 979 987 9839-year 913 936 945 953 972 958 973 965 962 966 970 976 979 980 979 98710-year 912 934 942 949 972 957 973 965 960 964 970 976 977 980 97911-year 912 932 940 946 972 957 973 965 958 964 970 976 977 97912-year 911 931 940 945 972 955 973 965 952 964 970 976 97713-year 909 929 940 944 972 955 973 955 949 964 970 97614-year 908 928 939 943 972 955 973 949 946 964 97015-year 907 924 938 940 967 950 973 943 944 96416-year 906 923 937 939 958 950 973 942 94417-year 904 923 936 939 958 950 971 94118-year 899 923 935 938 958 950 96719-year 898 923 932 938 958 95020-year 898 923 932 938 958

Table 2611Cancer of the Thyroid (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 002 011 122 006 Asian 0 000 002 010 128 011

10 002 011 029 123 006 Pacific 10 002 010 027 129 011

20 009 027 049 121 006 Islander 20 008 024 047 127 011

30 018 040 065 114 007 30 017 039 063 120 011

40 023 047 072 097 007 40 022 046 072 104 011

50 025 050 068 077 007 50 024 051 070 083 011

60 026 046 053 054 006 60 027 047 058 060 011

70 022 030 - 032 006 70 021 032 - 035 010

80 011 - - 013 005 80 013 - - 017 008

White 0 000 003 012 128 006 American 0 000 002 007 083 007

10 003 012 031 129 006 Indian 10 002 007 018 084 007

20 010 029 052 127 006 Alaska 20 005 016 026 083 007

30 019 043 069 118 006 Nativea 30 011 021 036 079 007

40 024 050 074 100 006 40 010 026 043 070 007

50 027 052 071 079 006 50 016 034 048 063 008

60 027 047 054 055 006 60 019 034 047 050 007

70 022 031 - 032 006 70 017 032 - 035 007

80 011 - - 013 005 80 020 - - 024 009

Black 0 000 001 004 074 006 Hispanicb 0 000 002 009 114 009

10 001 004 012 076 006 10 002 009 023 115 009

20 003 012 026 075 006 20 007 021 040 113 009

30 009 023 038 073 006 30 014 033 055 107 009

40 015 030 048 066 006 40 019 042 065 094 010

50 016 034 046 053 006 50 023 047 067 077 010

60 020 033 039 040 006 60 025 045 053 056 009

70 016 023 - 025 006 70 022 031 - 034 009

80 010 - - 013 005 80 011 - - 014 007

Table 2612

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 001 004 064 006 Asian 0 000 001 004 067 008

10 001 004 010 065 006 Pacific 10 001 004 010 067 008

20 003 009 019 064 006 Islander 20 003 009 020 066 008

30 007 016 029 062 006 30 007 017 028 064 008

40 010 022 038 056 006 40 010 021 036 058 008

50 013 029 042 048 006 50 011 026 039 048 008

60 017 031 037 038 006 60 016 029 038 038 008

70 016 023 - 024 005 70 015 024 - 025 007

80 010 - - 011 004 80 011 - - 012 006

White 0 000 001 004 068 006 American 0 000 001 003 034 006

10 001 004 011 069 006 Indian 10 001 003 006 035 006

20 003 010 020 068 006 Alaska 20 002 005 008 034 006

30 007 017 031 066 006 Nativea 30 003 006 010 033 006

40 010 024 040 060 006 40 002 007 015 030 006

50 014 031 045 051 006 50 005 013 022 030 007

60 018 033 039 039 006 60 009 019 027 027 007

70 017 024 - 025 005 70 011 020 - 021 007

80 010 - - 011 004 80 013 - - 014 008

Black 0 000 000 001 031 003 Hispanicb 0 000 001 003 050 007

10 000 001 004 031 004 10 001 003 007 050 007

20 001 003 008 031 004 20 002 006 012 050 007

30 003 007 014 031 004 30 004 011 020 048 007

40 004 012 020 029 004 40 006 016 028 045 007

50 008 016 023 026 004 50 010 022 033 039 007

60 010 017 021 021 004 60 013 025 030 031 007

70 010 014 - 014 003 70 013 019 - 020 006

80 007 - - 007 002 80 008 - - 010 005

Table 2613

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 004 019 181 007 Asian 0 000 003 016 183 013

10 004 018 048 182 007 Pacific 10 003 016 042 184 013

20 015 044 079 179 007 Islander 20 013 039 072 181 013

30 030 065 101 165 007 30 026 059 094 169 013

40 036 072 105 137 007 40 033 068 104 144 013

50 037 071 094 104 007 50 035 071 096 112 013

60 035 059 068 070 007 60 037 062 074 079 013

70 027 036 - 038 006 70 027 039 - 044 012

80 012 - - 015 005 80 015 - - 020 009

White 0 000 004 021 190 007 American 0 000 003 011 132 008

10 004 021 053 192 007 Indian 10 002 011 030 133 008

20 017 049 086 188 007 Alaska 20 009 027 044 131 008

30 032 070 108 172 007 Nativea 30 019 036 062 124 008

40 038 076 109 141 007 40 017 044 069 107 008

50 039 073 097 106 007 50 027 054 073 093 008

60 035 060 069 070 007 60 028 048 065 069 007

70 027 037 - 038 006 70 022 041 - 046 007

80 012 - - 014 005 80 024 - - 030 008

Black 0 000 001 007 114 008 Hispanicb 0 000 004 017 179 011

10 001 007 021 116 008 10 004 017 041 180 011

20 006 020 043 116 008 20 013 038 069 177 011

30 015 038 061 111 008 30 025 056 092 165 011

40 024 047 072 098 008 40 031 068 102 141 011

50 024 050 067 076 008 50 037 072 098 111 011

60 028 046 054 056 008 60 036 063 074 077 011

70 021 030 - 033 008 70 030 041 - 044 010

80 012 - - 016 006 80 014 - - 017 008

Table 2614

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 12: SEER Cancer Statistics Review 1975-2015

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 002 011 122 006 Asian 0 000 002 010 128 011

10 002 011 029 123 006 Pacific 10 002 010 027 129 011

20 009 027 049 121 006 Islander 20 008 024 047 127 011

30 018 040 065 114 007 30 017 039 063 120 011

40 023 047 072 097 007 40 022 046 072 104 011

50 025 050 068 077 007 50 024 051 070 083 011

60 026 046 053 054 006 60 027 047 058 060 011

70 022 030 - 032 006 70 021 032 - 035 010

80 011 - - 013 005 80 013 - - 017 008

White 0 000 003 012 128 006 American 0 000 002 007 083 007

10 003 012 031 129 006 Indian 10 002 007 018 084 007

20 010 029 052 127 006 Alaska 20 005 016 026 083 007

30 019 043 069 118 006 Nativea 30 011 021 036 079 007

40 024 050 074 100 006 40 010 026 043 070 007

50 027 052 071 079 006 50 016 034 048 063 008

60 027 047 054 055 006 60 019 034 047 050 007

70 022 031 - 032 006 70 017 032 - 035 007

80 011 - - 013 005 80 020 - - 024 009

Black 0 000 001 004 074 006 Hispanicb 0 000 002 009 114 009

10 001 004 012 076 006 10 002 009 023 115 009

20 003 012 026 075 006 20 007 021 040 113 009

30 009 023 038 073 006 30 014 033 055 107 009

40 015 030 048 066 006 40 019 042 065 094 010

50 016 034 046 053 006 50 023 047 067 077 010

60 020 033 039 040 006 60 025 045 053 056 009

70 016 023 - 025 006 70 022 031 - 034 009

80 010 - - 013 005 80 011 - - 014 007

Table 2612

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 001 004 064 006 Asian 0 000 001 004 067 008

10 001 004 010 065 006 Pacific 10 001 004 010 067 008

20 003 009 019 064 006 Islander 20 003 009 020 066 008

30 007 016 029 062 006 30 007 017 028 064 008

40 010 022 038 056 006 40 010 021 036 058 008

50 013 029 042 048 006 50 011 026 039 048 008

60 017 031 037 038 006 60 016 029 038 038 008

70 016 023 - 024 005 70 015 024 - 025 007

80 010 - - 011 004 80 011 - - 012 006

White 0 000 001 004 068 006 American 0 000 001 003 034 006

10 001 004 011 069 006 Indian 10 001 003 006 035 006

20 003 010 020 068 006 Alaska 20 002 005 008 034 006

30 007 017 031 066 006 Nativea 30 003 006 010 033 006

40 010 024 040 060 006 40 002 007 015 030 006

50 014 031 045 051 006 50 005 013 022 030 007

60 018 033 039 039 006 60 009 019 027 027 007

70 017 024 - 025 005 70 011 020 - 021 007

80 010 - - 011 004 80 013 - - 014 008

Black 0 000 000 001 031 003 Hispanicb 0 000 001 003 050 007

10 000 001 004 031 004 10 001 003 007 050 007

20 001 003 008 031 004 20 002 006 012 050 007

30 003 007 014 031 004 30 004 011 020 048 007

40 004 012 020 029 004 40 006 016 028 045 007

50 008 016 023 026 004 50 010 022 033 039 007

60 010 017 021 021 004 60 013 025 030 031 007

70 010 014 - 014 003 70 013 019 - 020 006

80 007 - - 007 002 80 008 - - 010 005

Table 2613

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2013-2015 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 004 019 181 007 Asian 0 000 003 016 183 013

10 004 018 048 182 007 Pacific 10 003 016 042 184 013

20 015 044 079 179 007 Islander 20 013 039 072 181 013

30 030 065 101 165 007 30 026 059 094 169 013

40 036 072 105 137 007 40 033 068 104 144 013

50 037 071 094 104 007 50 035 071 096 112 013

60 035 059 068 070 007 60 037 062 074 079 013

70 027 036 - 038 006 70 027 039 - 044 012

80 012 - - 015 005 80 015 - - 020 009

White 0 000 004 021 190 007 American 0 000 003 011 132 008

10 004 021 053 192 007 Indian 10 002 011 030 133 008

20 017 049 086 188 007 Alaska 20 009 027 044 131 008

30 032 070 108 172 007 Nativea 30 019 036 062 124 008

40 038 076 109 141 007 40 017 044 069 107 008

50 039 073 097 106 007 50 027 054 073 093 008

60 035 060 069 070 007 60 028 048 065 069 007

70 027 037 - 038 006 70 022 041 - 046 007

80 012 - - 014 005 80 024 - - 030 008

Black 0 000 001 007 114 008 Hispanicb 0 000 004 017 179 011

10 001 007 021 116 008 10 004 017 041 180 011

20 006 020 043 116 008 20 013 038 069 177 011

30 015 038 061 111 008 30 025 056 092 165 011

40 024 047 072 098 008 40 031 068 102 141 011

50 024 050 067 076 008 50 037 072 098 111 011

60 028 046 054 056 008 60 036 063 074 077 011

70 021 030 - 033 008 70 030 041 - 044 010

80 012 - - 016 006 80 014 - - 017 008

Table 2614

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

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Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 13: SEER Cancer Statistics Review 1975-2015

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Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 001 004 064 006 Asian 0 000 001 004 067 008

10 001 004 010 065 006 Pacific 10 001 004 010 067 008

20 003 009 019 064 006 Islander 20 003 009 020 066 008

30 007 016 029 062 006 30 007 017 028 064 008

40 010 022 038 056 006 40 010 021 036 058 008

50 013 029 042 048 006 50 011 026 039 048 008

60 017 031 037 038 006 60 016 029 038 038 008

70 016 023 - 024 005 70 015 024 - 025 007

80 010 - - 011 004 80 011 - - 012 006

White 0 000 001 004 068 006 American 0 000 001 003 034 006

10 001 004 011 069 006 Indian 10 001 003 006 035 006

20 003 010 020 068 006 Alaska 20 002 005 008 034 006

30 007 017 031 066 006 Nativea 30 003 006 010 033 006

40 010 024 040 060 006 40 002 007 015 030 006

50 014 031 045 051 006 50 005 013 022 030 007

60 018 033 039 039 006 60 009 019 027 027 007

70 017 024 - 025 005 70 011 020 - 021 007

80 010 - - 011 004 80 013 - - 014 008

Black 0 000 000 001 031 003 Hispanicb 0 000 001 003 050 007

10 000 001 004 031 004 10 001 003 007 050 007

20 001 003 008 031 004 20 002 006 012 050 007

30 003 007 014 031 004 30 004 011 020 048 007

40 004 012 020 029 004 40 006 016 028 045 007

50 008 016 023 026 004 50 010 022 033 039 007

60 010 017 021 021 004 60 013 025 030 031 007

70 010 014 - 014 003 70 013 019 - 020 006

80 007 - - 007 002 80 008 - - 010 005

Table 2613

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2013-2015 By RaceEthnicity

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1975-2015N

ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 004 019 181 007 Asian 0 000 003 016 183 013

10 004 018 048 182 007 Pacific 10 003 016 042 184 013

20 015 044 079 179 007 Islander 20 013 039 072 181 013

30 030 065 101 165 007 30 026 059 094 169 013

40 036 072 105 137 007 40 033 068 104 144 013

50 037 071 094 104 007 50 035 071 096 112 013

60 035 059 068 070 007 60 037 062 074 079 013

70 027 036 - 038 006 70 027 039 - 044 012

80 012 - - 015 005 80 015 - - 020 009

White 0 000 004 021 190 007 American 0 000 003 011 132 008

10 004 021 053 192 007 Indian 10 002 011 030 133 008

20 017 049 086 188 007 Alaska 20 009 027 044 131 008

30 032 070 108 172 007 Nativea 30 019 036 062 124 008

40 038 076 109 141 007 40 017 044 069 107 008

50 039 073 097 106 007 50 027 054 073 093 008

60 035 060 069 070 007 60 028 048 065 069 007

70 027 037 - 038 006 70 022 041 - 046 007

80 012 - - 014 005 80 024 - - 030 008

Black 0 000 001 007 114 008 Hispanicb 0 000 004 017 179 011

10 001 007 021 116 008 10 004 017 041 180 011

20 006 020 043 116 008 20 013 038 069 177 011

30 015 038 061 111 008 30 025 056 092 165 011

40 024 047 072 098 008 40 031 068 102 141 011

50 024 050 067 076 008 50 037 072 098 111 011

60 028 046 054 056 008 60 036 063 074 077 011

70 021 030 - 033 008 70 030 041 - 044 010

80 012 - - 016 006 80 014 - - 017 008

Table 2614

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

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ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

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1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 14: SEER Cancer Statistics Review 1975-2015

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ational Cancer Institute

Devcan 676 April 2018 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jerseyand Georgia excluding ATLRG) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area)counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 004 019 181 007 Asian 0 000 003 016 183 013

10 004 018 048 182 007 Pacific 10 003 016 042 184 013

20 015 044 079 179 007 Islander 20 013 039 072 181 013

30 030 065 101 165 007 30 026 059 094 169 013

40 036 072 105 137 007 40 033 068 104 144 013

50 037 071 094 104 007 50 035 071 096 112 013

60 035 059 068 070 007 60 037 062 074 079 013

70 027 036 - 038 006 70 027 039 - 044 012

80 012 - - 015 005 80 015 - - 020 009

White 0 000 004 021 190 007 American 0 000 003 011 132 008

10 004 021 053 192 007 Indian 10 002 011 030 133 008

20 017 049 086 188 007 Alaska 20 009 027 044 131 008

30 032 070 108 172 007 Nativea 30 019 036 062 124 008

40 038 076 109 141 007 40 017 044 069 107 008

50 039 073 097 106 007 50 027 054 073 093 008

60 035 060 069 070 007 60 028 048 065 069 007

70 027 037 - 038 006 70 022 041 - 046 007

80 012 - - 014 005 80 024 - - 030 008

Black 0 000 001 007 114 008 Hispanicb 0 000 004 017 179 011

10 001 007 021 116 008 10 004 017 041 180 011

20 006 020 043 116 008 20 013 038 069 177 011

30 015 038 061 111 008 30 025 056 092 165 011

40 024 047 072 098 008 40 031 068 102 141 011

50 024 050 067 076 008 50 037 072 098 111 011

60 028 046 054 056 008 60 036 063 074 077 011

70 021 030 - 033 008 70 030 041 - 044 010

80 012 - - 016 006 80 014 - - 017 008

Table 2614

Cancer of the Thyroid (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2013-2015 By RaceEthnicity

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 15: SEER Cancer Statistics Review 1975-2015

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 46 February 2018 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG

c The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 4 Joinpoints overdiagnosis years 1992-2015

d The 2006-2015 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2015

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry The 2006-2015 Hispanic andNon-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma

f Incidence data for American IndianAlaska Native are based on the CHSDA(Contract Health ServiceDelivery Area) counties

g US Mortality Files National Center for Health Statistics CDCh The 2006-2015 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2015 The APC is significantly different from zero (plt05)

SEER Incidence SEER 18 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2011-2015 Trend 2006-2015c Trend 2006-2015d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RACEETHNICITY

All Races 145 73 214 31 34 31 31 31 30

White 153 78 228 31 33 31 31 34 30White Hispanice 130 55 204 35 39 39 - - -White Non-Hispanice 162 85 239 30 34 29 - - -

Black 89 38 134 32 37 35 32 30 37

AsianPacific Islander 140 70 202 31 55 23 - - -

Amer IndAlaska Natf 93 40 143 37 25 40 - - -

Hispanice 125 53 196 35 39 37 - - -

US Mortalityg Rate 2011-2015 Trend 2006-2015h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRACEETHNICITY

All Races 05 05 05 07 13 05

White 05 05 05 07 14 02White Hispanice 06 06 07 03 13 -03White Non-Hispanice 05 05 04 07 14 02

Black 05 04 06 09 13 08

AsianPacific Islander 06 05 07 -05 03 -10

Amer IndAlaska NatTotal US 04 04 03 13 - -08CHSDA Counties 05 - 05 08 - -12Non-CHSDA Counties 03 - - - - -

Hispanice 06 05 07 01 12 -05

Table 2615Cancer of the Thyroid (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

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Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 16: SEER Cancer Statistics Review 1975-2015

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a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2011-2015

California 1294 644 1934 1321 658 1995 770 380 1130Greater Bay Area 1165 612 1719 1201 645 1785 514 258 753San Francisco-Oakland 1149 631 1660 1206 691 1749 505 271 709San Jose-Monterey 1199 579 1831 1198 568 1858 557 - 978

Los Angeles 1366 680 2025 1395 691 2104 926 447 1324Greater California 1306 638 1968 1325 647 2010 737 368 1109

Connecticut 1964 984 2898 2006 1018 2964 1165 507 1718Detroit 1651 821 2424 1857 924 2781 1120 502 1603Georgia 1199 598 1766 1375 707 2049 803 308 1205Atlanta 1216 624 1759 1440 789 2109 858 317 1275Rural Georgia 1166 404 1910 1459 - 2365 735 - 1248Greater Georgia 1195 589 1776 1351 677 2024 761 302 1149

Hawaii 1532 818 2267 1432 865 2123 - - -Iowa 1401 741 2070 1423 751 2101 790 - 1182Kentucky 1512 778 2230 1555 812 2282 1035 309 1698Louisiana 1377 691 2033 1563 813 2316 958 360 1463New Jersey 1924 1006 2801 2076 1099 3035 1004 475 1439New Mexico 1567 759 2360 1647 794 2490 - - -Seattle-Puget Sound 1404 742 2068 1406 768 2059 903 249 1629Utah 1926 943 2922 1970 960 2991 - - -

SEER 9 Areasb 1501 771 2214 1603 835 2383 921 386 1369SEER 13 Areasb 1448 737 2143 1528 785 2283 917 398 1355SEER 18 Areasb 1446 731 2143 1525 779 2277 895 383 1335

Table 2616Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

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a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

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a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

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Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

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Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

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0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

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0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

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Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 17: SEER Cancer Statistics Review 1975-2015

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a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2011-2015

California 062 058 065 061 058 064 050 040 053Greater Bay Area 054 047 060 052 041 061 - - -San Francisco-Oakland 057 050 062 054 044 062 - - -San Jose-Monterey 050 043 054 048 034 058 - - -

Los Angeles 070 066 071 071 067 073 065 - 062Greater California 061 057 064 060 059 061 041 - -

Connecticut 044 040 045 043 039 043 - - -Detroit 053 059 049 050 062 043 060 - 070Georgia 041 042 039 040 044 036 045 032 050Atlanta 043 042 043 042 046 037 040 - -Rural Georgia - - - - - - - - -Greater Georgia 040 043 036 039 044 034 051 - 052

Hawaii 060 064 057 - - - - - -Iowa 054 054 054 052 054 051 - - -Kentucky 050 053 047 050 054 047 - - -Louisiana 043 036 048 041 037 044 042 - 054New Jersey 049 054 045 049 054 046 047 - -New Mexico 052 049 054 057 054 059 - - -Seattle-Puget Sound 054 049 058 052 052 052 - - -Utah 057 071 047 059 072 048 - - -

SEER 9 Areasb 052 051 052 050 052 049 046 034 054SEER 13 Areasb 056 054 057 054 054 054 050 040 055SEER 18 Areasb 054 053 055 053 054 052 048 037 054

Total US 050 052 049 050 053 047 050 038 057

Table 2617Cancer of the Thyroid (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

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ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

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Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

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Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

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0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

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0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

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Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 18: SEER Cancer Statistics Review 1975-2015

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 050 001

High Five StatesDC 086 017 01(0147) 7050c

California 062 002 02(0215) 2346c

Alaska 062 016 03(0150) 2252c

Hawaii 060 008 04(0143) 1949c

Idaho 060 008 05(0147) 1872c

Low Five StatesGeorgia 041 003 46(2850) -1918c

Kansas 039 005 47(0550) -2176c

New Hampshire 037 007 48(1550) -2641c

Tennessee 037 003 49(2250) -2682c

Delaware 033 008 50(0150) -3373c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 045 004 38(0950) -992 Montana 046 009 36(0150) -760Alaska 062 016 03(0150) 2252c Nebraska 059 007 06(0145) 1786c

Arizona 045 003 39(0748) -999 Nevada 052 006 15(0249) 369Arkansas 047 005 32(0650) -665 New Hampshire 037 007 48(1550) -2641c

California 062 002 02(0215) 2346c New Jersey 049 003 23(0746) -254Colorado 049 004 25(0650) -344 New Mexico 052 007 16(0149) 309Connecticut 044 005 42(0750) -1276 New York 053 002 14(0535) 605Delaware 033 008 50(0150) -3373c North Carolina 050 003 19(0541) -085DC 086 017 01(0147) 7050c North Dakota 048 010 28(0250) -410Florida 042 002 44(2949) -1558c Ohio 049 003 24(0845) -311Georgia 041 003 46(2850) -1918c Oklahoma 047 005 33(0349) -701Hawaii 060 008 04(0143) 1949c Oregon 057 005 08(0247) 1360Idaho 060 008 05(0147) 1872c Pennsylvania 050 002 20(0639) -101Illinois 048 003 29(1046) -452 Rhode Island 045 008 40(0150) -1032Indiana 048 004 26(0849) -396 South Carolina 048 004 30(0750) -456Iowa 054 005 13(0248) 724 South Dakota 045 010 41(0150) -1077Kansas 039 005 47(0550) -2176c Tennessee 037 003 49(2250) -2682c

Kentucky 050 005 17(0347) -069 Texas 055 002 09(0533) 949Louisiana 043 004 43(0850) -1380 Utah 057 007 07(0149) 1389Maine 047 007 35(0450) -734 Vermont 041 010 45(0150) -1763c

Maryland 048 004 27(0950) -401 Virginia 047 003 31(0748) -584Massachusetts 054 004 11(0340) 788 Washington 054 004 12(0446) 776Michigan 050 003 18(0645) -078 West Virginia 045 006 37(0250) -966Minnesota 049 004 22(0649) -194 Wisconsin 055 004 10(0241) 899Mississippi 047 006 34(0350) -715 Wyoming - - -(--) -Missouri 049 004 21(0547) -183

Table 2618Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males and Females

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

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ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

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Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

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Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

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0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

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0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

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Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 19: SEER Cancer Statistics Review 1975-2015

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 052 001

High Five StatesOregon 071 008 01(0137) 3785c

Utah 071 012 02(0139) 3724c

Massachusetts 067 006 03(0133) 2968c

Idaho 066 013 04(0141) 2683c

Nebraska 065 012 05(0141) 2546c

Low Five StatesWest Virginia 039 009 40(0242) -2370c

Maryland 039 005 41(1342) -2524c

Maine 038 010 42(--) -2628c

Kansas 038 007 43(0342) -2648c

Louisiana 036 006 44(0842) -3012c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 048 006 34(0642) -738 Montana 062 015 08(0142) 1888c

Alaska - - -(--) - Nebraska 065 012 05(0141) 2546c

Arizona 056 006 13(0238) 810 Nevada 048 008 31(0242) -658Arkansas 051 008 25(0942) -183 New Hampshire 048 012 32(--) -658California 058 003 11(0531) 1123 New Jersey 054 005 18(0440) 398Colorado 060 008 09(0141) 1557c New Mexico 049 010 29(0242) -495Connecticut 040 006 39(0542) -2315c New York 052 003 23(0535) -003Delaware - - -(--) - North Carolina 050 005 26(0236) -355DC - - -(--) - North Dakota - - -(--) -Florida 042 003 37(2442) -1963c Ohio 049 004 28(0539) -470Georgia 042 005 38(2142) -1976c Oklahoma 050 007 27(0242) -420Hawaii 064 013 06(0142) 2376c Oregon 071 008 01(0137) 3785c

Idaho 066 013 04(0141) 2683c Pennsylvania 053 004 22(0436) 158Illinois 049 004 30(0841) -537 Rhode Island 064 015 07(0142) 2376c

Indiana 053 006 19(0542) 330 South Carolina 052 007 24(0241) -020Iowa 054 008 17(0142) 409 South Dakota - - -(--) -Kansas 038 007 43(0342) -2648c Tennessee 044 005 36(0942) -1594c

Kentucky 053 007 21(0242) 212 Texas 058 003 10(0228) 1226Louisiana 036 006 44(0842) -3012c Utah 071 012 02(0139) 3724c

Maine 038 010 42(--) -2628c Vermont - - -(--) -Maryland 039 005 41(1342) -2524c Virginia 048 005 33(0238) -697Massachusetts 067 006 03(0133) 2968c Washington 053 006 20(0340) 269Michigan 055 005 15(0439) 653 West Virginia 039 009 40(0242) -2370c

Minnesota 055 007 14(0241) 691 Wisconsin 057 006 12(0239) 946Mississippi 044 008 35(0442) -1547c Wyoming - - -(--) -Missouri 054 006 16(0340) 438

Table 2619Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Males

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

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ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

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Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

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Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

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0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

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0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

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Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 20: SEER Cancer Statistics Review 1975-2015

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 049 001

High Five StatesDC 100 024 01(0144) 10552c

California 065 002 02(0110) 3381c

Hawaii 057 011 03(0137) 1748c

Maryland 056 006 04(0343) 1402Washington 055 005 05(0342) 1234

Low Five StatesKansas 041 007 38(0444) -1671c

Colorado 041 005 39(0744) -1677c

Georgia 039 004 40(1544) -2100c

Arizona 036 004 41(1044) -2581c

Tennessee 032 004 42(1844) -3366c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 043 005 37(0544) -1198 Montana - - -(--) -Alaska - - -(--) - Nebraska 050 009 14(0144) 297Arizona 036 004 41(1044) -2581c Nevada 054 008 09(0244) 993Arkansas 044 007 35(0244) -1041 New Hampshire - - -(--) -California 065 002 02(0110) 3381c New Jersey 045 004 27(0542) -679Colorado 041 005 39(0744) -1677c New Mexico 054 009 07(0143) 1093Connecticut 045 006 30(0544) -838 New York 054 003 08(0430) 1082Delaware - - -(0144) - North Carolina 050 004 15(0441) 209DC 100 024 01(0144) 10552c North Dakota - - -(--) -Florida 043 002 36(1843) -1149 Ohio 047 003 20(0741) -278Georgia 039 004 40(1544) -2100c Oklahoma 044 006 34(0444) -1034Hawaii 057 011 03(0137) 1748c Oregon 045 006 28(0544) -690Idaho 053 011 10(0144) 873 Pennsylvania 047 003 19(0537) -271Illinois 046 003 24(0742) -559 Rhode Island - - -(--) -Indiana 044 005 31(0644) -977 South Carolina 044 005 33(0844) -1020Iowa 054 007 06(0344) 1123 South Dakota - - -(0144) -Kansas 041 007 38(0444) -1671c Tennessee 032 004 42(1844) -3366c

Kentucky 047 006 21(0242) -279 Texas 052 003 11(0636) 766Louisiana 048 006 18(0444) -117 Utah 047 009 23(0344) -453Maine 051 010 13(0144) 445 Vermont - - -(--) -Maryland 056 006 04(0343) 1402 Virginia 047 004 22(0844) -287Massachusetts 044 004 32(0443) -1014 Washington 055 005 05(0342) 1234Michigan 046 004 26(0642) -655 West Virginia 049 008 16(0244) -019Minnesota 045 005 29(0644) -764 Wisconsin 052 005 12(0240) 564Mississippi 048 007 17(0244) -061 Wyoming - - -(--) -Missouri 046 005 25(0644) -632

Table 2620Cancer of the Thyroid (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2011-2015

Females

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

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Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

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1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 21: SEER Cancer Statistics Review 1975-2015

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ational Cancer Institute

a US 2015 cancer prevalence counts are based on 2015 cancer prevalence proportions from the SEER registries and 112015US population estimates based on the average of 2014 and 2015 population estimates from the US Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 4023 years

b c d Statistics based on (b) SEER 9 Areas (c) SEER 13 Areas excluding the Alaska Native Registry(d) NHIA for Hispanic for SEER 13 Areas excluding the Alaska Native Registry

e Maximum limited-duration prevalence 40 years for 1975-2015 SEER 9 data 23 years for 1992-2015 SEER 13 data(excluding the Alaska Navtive Registry) used to calculate prevalence for Hispanics and Asian Pacific Islanders

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsg h i (g) Cases diagnosed more than 40 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000) (h) Complete prevalence is obtained by summing 0 to lt40 and gt=40 (i) Age-specific completeness indexwas approximated using empirical data from historical Connecticut tumor registry

- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt25 25 to lt30 0 to lt23e 0 to lt40e gt=40g Completeh

Race Sex All Racesb Both Sexes 231485 174502 110198 71321 50391 37800 637896 726654 38893 765547

Males 55337 39329 23314 14799 11003 7542 143780 161902 9217 171119Females 176148 135173 86884 56522 39388 30258 494116 564752 29676 594428

Whiteb Both Sexes 196650 152120 96832 62899 45124 33977 553621 633780 35166 668946Males 48585 35345 20975 13438 10074 6966 128415 145025 7691 152716Females 148065 116775 75857 49461 35050 27011 425206 488755 27475 516230

Blackb Both Sexes 16910 10745 6583 3687 2492 1644 40417 44359 1682 46041Males 2959 1765 1201 558 499 270 6982 7622 197 7819Females 13951 8980 5382 3129 1993 1374 33435 36737 1485 38222

Asian Both Sexes 12085 8242 5106 + + + 30146 + + +Pacific Males 2520 1508 881 + + + 5670 + + +Islanderc Females 9565 6734 4225 + + + 24476 + + +

Hispanicd Both Sexes 25101 16241 10145 + + + 60459 + + +Males 4784 2740 1723 + + + 10744 + + +Females 20317 13501 8422 + + + 49715 + + +

Age Specific (Crude) Age-Adjustedf Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex All Racesc Both Sexes 01822 00002 00066 00461 01515 02773 03504 03801 03886 02711 01715

Males 00812 - 00027 00159 00494 01068 01483 02035 02471 01898 00786Females 02806 00003 00105 00779 02546 04461 05448 05396 05049 03204 02599

Whitec Both Sexes 02006 00002 00075 00532 01692 03049 03820 03996 04009 02784 01854Males 00920 - 00030 00187 00542 01195 01645 02215 02637 01986 00861Females 03088 - 00121 00901 02905 04968 05985 05665 05167 03277 02840

Blackc Both Sexes 00908 - 00018 00146 00670 01446 01862 02490 02922 01833 00970Males 00326 - - 00037 00180 00445 00675 01019 01612 01348 00391Females 01438 - 00030 00254 01104 02319 02900 03644 03836 02075 01450

Asian Both Sexes 01633 - 00059 00375 01270 02444 03069 03526 03701 02674 01535Pacific Males 00647 - 00035 00112 00450 00899 01173 01608 01966 01586 00644Islanderc Females 02539 - 00084 00644 02019 03810 04705 05090 05060 03346 02298

Hispanicd Both Sexes 01120 - 00066 00365 01169 01998 02803 03210 03519 02554 01383Males 00393 - 00031 00114 00308 00655 00939 01428 01951 01506 00543Females 01858 - 00103 00636 02087 03391 04618 04761 04696 03188 02183

Table 2621Cancer of the Thyroid (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2015By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2015 of the SEERc population diagnosed in the previous 23 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 22: SEER Cancer Statistics Review 1975-2015

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 8050 8140-8147 8160-8162 8180-8221 8250-8507 8514 8520-8551 8560 8570-8574 8576

8940-8941f Other specific carcinomas include histologies 8013-8015 8033-8046 8150-8155 8170-8171 8230-8249 8510 8512 8561-8562

8575 8580-8671g Sarcoma and other soft tissue tumors include histologies 8680-8713 8800-8921 8990-8991 9040-9044 9120-9136 9150-9252

9370-9373 9540-9582h Other specific types include histologies 8720-8790 8930-8936 8950-8983 9000-9030 9060-9110 9260-9365 9380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 65324 997 52285 997 4627 997 6858 997 314 1000 10507 997Epidermoid carcinomad 69 01 56 01 - - - - - - - -(8051-8131)

Adenocarcinomae 63330 966 50684 967 4448 958 6675 970 305 971 10208 969Papillary adenocarcinoma 58812 898 47185 900 3912 843 6286 914 283 901 9606 912(805082608340-834483508450)

Follicular carcinoma 2966 45 2258 43 382 82 268 39 - - 424 40(8330-83328335)

Oxyphilic (8290) 1205 18 968 18 120 26 86 13 - - 139 13Other specific carcinomasf 1100 17 921 18 84 18 78 11 - - 172 16Medullary carcinoma (8510) 1057 16 886 17 81 17 74 11 - - 165 16

Carcinoma NOS 825 13 624 12 91 20 97 14 - - 120 11(80048010-80128020-80228030-8032)Anaplastic carcinoma 524 08 408 08 49 11 62 09 - - 78 07(800480128020-80218030-8032)

Sarcoma and other soft tissue 17 00 - - - - - - - - - -tumorsg

Other specific typesh - - - - - - - - - - - -

Unspecified (8000-80038005) 180 03 130 02 - - 20 03 - - 23 02

Total 65528 1000 52436 1000 4642 1000 6878 1000 314 1000 10536 1000

Table 2622

Cancer of the Thyroid (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2011-2015Both Sexes by Race

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 23: SEER Cancer Statistics Review 1975-2015

0

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 20150

5

10

15

20

25

1975 1985 1995 2005 2015

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Thyroid by Race and Sex

a

Figure 261

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

US Mortality APC1984-15 = 12

SEER Incidence APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30US Mortality APC1975-15 = 04

SEER Incidence APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09US Mortality APC1988-15 = 03

SEER Incidence APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

US Mortality APC1975-15 = 00

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

R C

ancer Statistics Review

1975-2015N

ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 24: SEER Cancer Statistics Review 1975-2015

Joinpoint Analyses for Whites and Blacks from 1975-2015and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 1992-2015

0

5

10

15

20

1975 1985 1995 2005 20150

5

10

15

20

1975 1985 1995 2005 2015

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Thyroid Both Sexes

Figure 262

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas San Jose-MontereyLos Angeles Alaska Native Registry and Rural Georgia) Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2015 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 1992-2015 allow a maximum of 4 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the CHSDA(Contract Health Service Delivery Area) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry Mortality data for Hispanics exclude cases from New Hampshire and Oklahoma

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

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ancer Statistics Review

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ational Cancer Institute

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

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ancer Statistics Review

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ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

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ancer Statistics Review

1975-2015N

ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 25: SEER Cancer Statistics Review 1975-2015

0

1

3

4

5

6

8

9

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 20150

2

4

6

8

10

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Male by Race

aFigure 263

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2012-15 = -11Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2009-15 = 25Observed 2009-15 = 24

SEER 9 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 13 APCsDelay Adj 2009-15 = 23Observed 2009-15 = 21

SEER 9 APCsDelay Adj 1975-15 = 30Observed 1975-15 = 30

SEER 13 APCsDelay Adj 1992-15 = 38Observed 1992-15 = 37

SEE

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ancer Statistics Review

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ational Cancer Institute

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

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ancer Statistics Review

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ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 26: SEER Cancer Statistics Review 1975-2015

0

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 20150

5

10

15

20

25

30

1975 1985 1995 2005 2015

SEER 9 Delay-Adj IncidenceSEER 9 Delay-Adj Incidence SEER 9 Observed IncidenceSEER 9 Observed Incidence SEER 13 Delay-Adj IncidenceSEER 13 Delay-Adj Incidence SEER 13 Observed IncidenceSEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence RatesSEER 9 Areas Compared to SEER 13 Areas

Cancer of the Thyroid Female by Race

aFigure 264

Source SEER 9 areas and SEER 13 areasRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 46 February 2018 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

All Races White BlackRate per 100000 Rate per 100000 Rate per 100000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCsDelay Adj 2009-15 = 12Observed 2009-15 = 10

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 2009-15 = 11Observed 2009-15 = 09

SEER 13 APCsDelay Adj 2009-15 = 14Observed 2009-15 = 12

SEER 9 APCsDelay Adj 1989-15 = 55Observed 2012-15 = -14

SEER 13 APCsDelay Adj 2011-15 = -06Observed 2011-15 = -11

SEE

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ancer Statistics Review

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ational Cancer Institute

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival
Page 27: SEER Cancer Statistics Review 1975-2015

Figure 265

Cancer of the Thyroid5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG) California excluding SFSJMLA KentuckyLouisiana New Jersey and Georgia excluding ATLRG contribute cases for diagnosis years 2000 and laterThe remaining 13 SEER Areas contribute cases for the entire time periodPercent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

1998-2014 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2015 National Cancer Institute

  • Trends in SEER Incidence and US Mortality Both Sexes
  • Trends in SEER Incidence and US Mortality Males
  • Trends in SEER Incidence and US Mortality Females
  • Annual Delay-adjusted Incidence Rates
  • Annual Incidence Rates
  • Annual Death Rates
  • Incidence and Mortality Rates by Age
  • 5-year Relative and Period Survival
  • Relative Survival by Year of Diagnosis Both Sexes
  • Relative Survival by Year of Diagnosis Males
  • Relative Survival by Year of Diagnosis Females
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Risk of DevelopingDying
  • Rates and Trends by RaceEthnicity
  • Age-Adjusted SEER Incidence Rates by Registry
  • Age-Adjusted SEER Death Rates by Registry
  • Age-Adjusted Cancer Death Rates By State Both Sexes
  • Age-Adjusted Cancer Death Rates By State Males
  • Age-Adjusted Cancer Death Rates By State Females
  • US Prevalence Estimates
  • Case Distribution by Histology
  • Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
  • Graph - SEER Incidence and US Death Rates by RaceEthnicity
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Males
  • Graph - SEER Delay Adjusted Incidence Rates for SEER 9 and SEER 13 Areas Females
  • Graph - 5-Year SEER Conditional Relative Survival