screening of plant extracts for biological activity€¦ · 1as jornadas do projeto interact...
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1as Jornadas do Projeto INTERACT
SCREENING OF PLANT EXTRACTS FOR BIOLOGICAL ACTIVITY
Focus on Asteracea and Lamiaceae familyLuís Félix
Prof. Dr. Amélia Silva and Prof. Dr Carlos VenâncioISAC, P4 – Bioactives from vegetable crops, MAPs and natural co-products
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INTRODUCTION
• Plants have been used as drugs by humans since thousands of years ago.• basis of sophisticated Traditional Medicine.
• Nowadays, they continue to have an important role in healthcare.• natural products are still being used/studied as new medicines with potential for novel drug leads as valuable
and important part in pharmaceutical, food, and cosmetic industries.
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INTRODUCTION
• Species from Asteracea and Lamiaceae family are common in aromatic plantcommunities in the western Mediterranean.
• Their biological properties and composition have been
described in recent years and are reported as important
families for the pharmaceutical, food, and cosmetic
industries with increasing economic value.
• However, much of the potential effects and benefits of this plant remains largely undescribed and more research is still need in order to prove all its many potentials.
• Nonvolatile constituents have been less studied.
http://www.qca.pt/iniciativas/mapa4.html
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OBJECTIVES
• Obtain bioactives from selected species: . Thymus vulgaris
• Thymus frangrantissimus (hybrid)
• Santolina rosmarinifolia (Iberian Pen. endemic)
• Salvia (Iberian Pen. endemic - planned)
Thymus vulgaris Thymus fragrantissimus Santolina rosmarinifolia
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OBJECTIVES
• Validate their biological properties by several methodologies, frombiochemical assays to experiments on cellular and animal models.• Focus on neuroprotective, anti-inflammatory, anti-oxidant and toxicological properties.
• Valorize phytochemicals for emerging industrial applications.
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FRAMEWORK