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  • 8/6/2019 Scientist or Applications Scientist

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    Martin Thomas Sommer410 Warrenville RoadMansfield, Connecticut 06250(860) [email protected]

    Employment Experience

    Six Sigma Consultant May 2010 -September 2010* Improved process flow of operational transfer for non-profit organization* Established methods for tracking results by statistical analysis* Developed surveys for assessing customer needs and satisfaction

    Field Applications Scientist, SpinX Technologies, SA February 2008 -Geneva, Switzerland October 2008

    * Developed protocols for kinase and peptidase assays on novel microfluidics platform* Validated assay parameters as required by engineering and software groups* Established and maintained relationships with academic researchers

    Bioscience and education consultant, MS Bioconsulting January 2006 -Mansfield, Connecticut January 2008

    * Conducted web-based market research and analysis of the biotechnology industry* Lobbied Connecticut legislature and local governments in support of science and education initiatives for a Connecticut film and media group

    Senior Scientist, PerkinElmer Life Sciences July 2000 -Boston, MA October 2005(formerly Packard BioScience, Meriden, CT)* Improved reaction conditions for enzymatic neonatal diagnostic tests* Optimized antibody-ligand ratios for AlphaScreen* GST protein interaction kit

    * Developed multiplexed cytokine assay for 42 ligands on HydroGel* protein arrayplatform* Characterized protein binding capacity and substrate stability of HydroGel* protein array slides

    Research Scientist, Dr. Alexandros Makriyannis' lab August 1999 -University of Connecticut, Storrs, CT July 2000

    * Established novel transfected cell lines expressing cannabinoid receptors CB1and CB2* Screened ligands for binding to cannabinoid receptors and estrogen receptors

    Staff Scientist, Genaissance Pharmaceuticals, New Haven, CT October 1997 -

    August 1999* Isolated and cloned novel variants of human estrogen receptors* Expressed and purified estrogen receptor proteins for functional assays* Developed filter plate-based assay for screening ligand binding to estrogen receptors* Validated estrogen receptor variants through selevtive binding assays

    Academic Experience

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    Visiting Professor, Genetics January - MayThe University of Connecticut, Storrs, CT 2002

    Visiting Professor, Medical Genetics, June - OctoberUniversity of Health Sciences, Saint John's, Antigua 1997

    Postdoctoral Associate, Dr. Joel D. Richter's lab August 1996-Worcester Foundation for Biomedical Research, Shrewsbury, MA June 1997

    Visiting Lecturer, Molecular Biology Laboratory Techniques September -Connecticut College, New London, CT December 1995

    Education

    Ph.D. Genetics, The University of Connecticut, Storrs, CT 1996M.S. Microbiology, The University of Bridgeport, Bridgeport, CT 1988B.S. Microbiology, North Carolina State University, Raleigh, NC 1982

    Publications

    * Crayton, M.E. III, C.E. Ladd, M.T. Sommer, G. Hampikian and L.D. Strausbaugh.2004. An organizational model of transcription factor binding sites for a histon

    e promoter in D. melanogaster. In Silico Biology 4, 0045 (October, 2004) http://www.bioinfo.de/isb/2004/04/0045/* Sommer, M.T., C.C. Wang, H. Lisoukov, R. Cavallo, T.E. Miller and J. Burke. 2002. Parallel immunoassays on HydroGel* biochips using microspot arrays. Proceedings of the International Society for Photonics and Engineering. 4626:49-57.* Wang, C.C., R.-P. Huang, M. Sommer, H. Lisoukov, R. Huang, Y. Lin, T. Miller and J. Burke. 2002. Array-based multiplexed screening and quantitation of human cytokines and chemokines. Journal of Proteome Research. 1:337-343.* Miller, T.E., M.T. Sommer, K.L. Woodward, H.N. Lisoukov, Q. Wang and R. Cavallo. Drug Discovery Assay Tutorial: Two-Site Immunometric Biochips. Genetic Engineering News. 2002. 22:33-35.* Strausbaugh, L.D., M.T. Bourke, M.T. Sommer, M.E. Coon and C.M. Berg. 1990. Probe mapping to facilitate transposon-based DNA sequencing. Proceedings of the

    National Academy of Sciences. 87: 6213-6217.

    Invited Oral Presentations

    * Sommer, M.T. 2002. HydroGel* substrate as a platform for protein microarray applications. 2nd Annual International Conference BioChips 2002 (The Knowledge Foundation). Richmond, VA.* Sommer, M.T. 2002. Parallel immunoassays on HydroGel* biochips using microspotarrays. International Society for Photonics and Engineering. San Jose, CA.* Sommer, M.T. and L.D. Strausbaugh. 1994. Identification of elements in the H2A-H2B intergenic spacer involved in regulation of the histone H2A gene. 35th Annual Drosophila Research Conference. Chicago, IL.

    Skills

    Protein microarray design, production, optimization and data analysis; immunoassay techniques; molecular cloning and DNA manipulation; protein expression and purification; compound profiling and mode of action studies; assay development andoptimization; microfluidics applications; PCR; excellent presentation skills

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    Additional Training

    * Six Sigma Black Belt, Central Connecticut State Unniversity, 2010* Reporting Failure Investigations and Process Deviations, CPIE, 2005* Drug and Drug Product Stability, Center for Professional Advancement, 2004* Results Based Leadership, PerkinElmer Life Sciences, 2005* Microsoft Project Manager, Boston University School of Continuing Education ,2004