rt 4912 review (c) rex t. christensen mha rt (r) (mr) (ct) (arrt) ciip

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RT 4912 Review RT 4912 Review (C) (C) Rex T. Christensen MHA RT (R) (MR) (CT) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP (ARRT) CIIP

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MR Active Nuclei (cont.) Odd atomic number. Odd atomic number. (even proton, odd neutron or vice versa). Spinning mass (magnetic field-example earth). Spinning mass (magnetic field-example earth). Spinning mass with a charge. Spinning mass with a charge.

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Page 1: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

RT 4912 Review RT 4912 Review (C)(C)

Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIPCIIP

Page 2: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

MR Active NucleiMR Active Nuclei Nuclei that aligns its axis to a Nuclei that aligns its axis to a

magnetic field.magnetic field. They do this because of They do this because of

electromagnetic induction:electromagnetic induction: Angular momentum or Angular momentum or spinspin.. Posses an electrical Posses an electrical chargecharge (+) (+) If two of these characteristics are If two of these characteristics are

present it induces the third - present it induces the third - magnetismmagnetism

Called a Called a magnetic momentmagnetic moment

Page 3: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

MR Active Nuclei (cont.)MR Active Nuclei (cont.) Odd atomic number.Odd atomic number.

(even proton, odd neutron or vice (even proton, odd neutron or vice versa).versa).

Spinning mass (magnetic field-Spinning mass (magnetic field-example earth).example earth).

Spinning mass with a charge.Spinning mass with a charge.

Page 4: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

PrecessionPrecessionPrecession is the wobble of a top

Precessional Frequency is the speed it wobbles. (Mhz)

Page 5: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

The Larmor frequency is also The Larmor frequency is also called the Precessional called the Precessional frequency. frequency.

Precession is a “wobble” of the Precession is a “wobble” of the hydrogen atom.hydrogen atom.

Larmor Frequency:Larmor Frequency:

Page 6: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

Larmor Equation:Larmor Equation:MEMORIZE THIS!

Page 7: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

Hydrogen Atoms Hydrogen Atoms beforebefore being placed in the MRI:being placed in the MRI:

Page 8: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

Hydrogen Atoms Hydrogen Atoms afterafter being placed in the MRI:being placed in the MRI:

Page 9: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

Parallel vs. Anti-parallel:Parallel vs. Anti-parallel:

Anti-parallel = High energy states.

Parallel = Low energy states.

Anti-parallel

Parallel

Page 10: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

Net Magnetization:Net Magnetization:

Page 11: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

Longitudinal and Longitudinal and Transverse Transverse

MagnetizationMagnetizationLongitudinal Magnetization is also known as:

• T1 Relaxation

• Spin-lattice Relaxation

• T1 recovery

Transverse Magnetization is also known as:

• T2 Relaxation

• Spin-spin Relaxation

• T2 Decay

Page 12: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

Resonance:Resonance:When an RF pulse is turned on and its frequency matches that of the frequency of the hydrogen atom energy is transferred. This tips the hydrogen atoms down into the transverse plane (90 degrees).

The magnitude of the flip angle (i.e. 90 degrees) depends upon the amplitude and duration of the RF pulse.

Page 13: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

T1 Relaxation:T1 Relaxation:

Page 14: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

T1 Relaxation:T1 Relaxation:

Page 15: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

T2 Relaxation:T2 Relaxation:This relaxation is also called:

•Dephasing

•Incoherence

•Lack of phase coherence

•T2 Decay

Coherence: means sticking together.

Page 16: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

T2 Relaxation:T2 Relaxation:

Page 17: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

Free Induction Decay Free Induction Decay (FID):(FID):

Coils can be transmit and receive, but most are receive only.

The external body coil is usually the transmitter.

Page 18: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

CoilsCoils

Page 19: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

CoilsCoils

Page 20: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

Free Induction Decay Free Induction Decay (FID):(FID):

The induction in reduced signal is called Free Induction Decay (FID)

Page 21: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

TR = TR = TTime to ime to RRepetitionepetition

Time (ms) between the beginning of one pulse sequence and the beginning of the succeeding pulse sequence.

Page 22: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

TE = TE = TTime to ime to EEchocho

Time (ms) between the beginning of the 90-degree pulse and the center of the spine echo.

Page 23: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

Image Contrast: Image Contrast: MRI Made Easy 21 MRI Made Easy 21 - 22- 22

T1 contrast = short TR and short TE.T1 contrast = short TR and short TE.T2 contrast = long TR and long TE.T2 contrast = long TR and long TE.PD contrast = long TR and short TE.PD contrast = long TR and short TE.

Page 24: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

Spin Echo Contrasts

T1

PD T2

TE

TR

2500

2000

1500

1000

500

30 90

Page 25: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

The net magnetization vectorThe net magnetization vectorLongitudinal and transverse componentsLongitudinal and transverse components

The spins precess at the Larmor frequency around the z-axis. The net magnetization points in the z-direction.

Unless we have applied an RF field, there is no net xy-magnetization.

We measure the xy-magnetization during recovery.

Page 26: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

Mxy

37%

T2t

Transverse Relaxation Time T2

Transverse Relaxation = Decay of magnetization by interaction between nuclei (Spin-Spin-Relaxation)

Page 27: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

MoMz

t

63%

T1

Longitudinal Relaxation Time T1

Longitudinale Relaxation = Energy transfer between excited spins andTissue (Spin-Lattice-Relaxation)

Reestablishing of longitudinal magnetization with time constant T1

Page 28: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

Mz S

Tissue 1

Tissue 2

TR Short TE Medium TE Long TE

Longitudinal Relaxation Transverse Relaxation

Tissue 2

Tissue 1

Relaxation Times are Tissue Specific

Page 29: RT 4912 Review (C) Rex T. Christensen MHA RT (R) (MR) (CT) (ARRT) CIIP

References:References:Westbrook, Catherine and Kaut, Carolyn (1998). MRI In Westbrook, Catherine and Kaut, Carolyn (1998). MRI In

Practice, 3rd Edition, Malden, MA: Blackwell Science, Inc.Practice, 3rd Edition, Malden, MA: Blackwell Science, Inc.