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Rodent Breeding Colonies Bill Greer Penn State

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Page 1: Rodent Breeding Colonies Bill Greer Penn State. The most Common Models Colonies maintained by Animal Resources Colonies are maintained by PI’s

Rodent Breeding Colonies

Bill GreerPenn State

Page 2: Rodent Breeding Colonies Bill Greer Penn State. The most Common Models Colonies maintained by Animal Resources Colonies are maintained by PI’s

The most Common ModelsThe most Common Models

Colonies maintained by Animal ResourcesColonies maintained by Animal Resources

Colonies are maintained by PI’sColonies are maintained by PI’s

Page 3: Rodent Breeding Colonies Bill Greer Penn State. The most Common Models Colonies maintained by Animal Resources Colonies are maintained by PI’s

OK, so What’s the Problem?OK, so What’s the Problem?

Numbers Counting Transferring Strain Maintenance Transgenic animals?

Page 4: Rodent Breeding Colonies Bill Greer Penn State. The most Common Models Colonies maintained by Animal Resources Colonies are maintained by PI’s

Problems – Ice Cream!!

Page 5: Rodent Breeding Colonies Bill Greer Penn State. The most Common Models Colonies maintained by Animal Resources Colonies are maintained by PI’s

How Many to ProduceHow Many to Produce

How may the Animal Resource Program justify numbers?

How may the PI justify numbers? Maintain the strain Research needs

• Loss due to genotype• Can only use one sex (M or F)

Page 6: Rodent Breeding Colonies Bill Greer Penn State. The most Common Models Colonies maintained by Animal Resources Colonies are maintained by PI’s

When do you count the animals?When do you count the animals?

At

Birth

Weaning, or

Somewhere in between (e.g., first cage change)

Page 7: Rodent Breeding Colonies Bill Greer Penn State. The most Common Models Colonies maintained by Animal Resources Colonies are maintained by PI’s

Transferring from Breeding to Research Transferring from Breeding to Research Protocols?Protocols?

Counting against other protocols

Using it for research/teaching or testing?

When to count Tracking the transfers

Page 8: Rodent Breeding Colonies Bill Greer Penn State. The most Common Models Colonies maintained by Animal Resources Colonies are maintained by PI’s

Any Guide Deviations?Any Guide Deviations?

Maybe,

Single housing

Trio Breeding

Delayed cage changes

Page 9: Rodent Breeding Colonies Bill Greer Penn State. The most Common Models Colonies maintained by Animal Resources Colonies are maintained by PI’s

Transgenic?Transgenic?

Who’s making them – ARP, the PI, a service unit? IACUC and IBC Protocol

Any problematic phenotypes

Page 10: Rodent Breeding Colonies Bill Greer Penn State. The most Common Models Colonies maintained by Animal Resources Colonies are maintained by PI’s

How about if transgenic animals are made offsite

Using PHS funds?

Are you AAALAC accredited; is your collaborator?- Who owns the animals

Need an MOU?

Page 11: Rodent Breeding Colonies Bill Greer Penn State. The most Common Models Colonies maintained by Animal Resources Colonies are maintained by PI’s

What did we miss?What did we miss?


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Honey bee (Apis mellifera) sociability and nestmate ... › content › jexbio › early › ...All honey bee (Apis mellifera) colonies were maintained at Macquarie University Fauna

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