MicroRNAsFrom Basic Science to Disease Biology

Edited by Krishnarao AppasaniForewords by Victor R. Ambros and Sidney Altman

Pre-publication praise for MicroRNAs

“This book contains much up-to-date information about the fast growing field of micro-RNA

research. The book should be very useful to anyone interested in miRNA.”

Marshall Nirenberg, Nobel Laureate

“… a useful reference for researchers wanting to know the state-of-the art in microRNA

research. Knowledge in the field has exploded so quickly that it is difficult to get a sense of what

is known and what is not known … a timely summary of many important topics in microRNA

research.”

Dr. Peter Linsley, Executive Director

Merck-Rosetta Inpharmatics LLC, Seattle, USA

“MicroRNAs – From Basic Science to Disease Biology, is for people who are willing to continuously

expand knowledge about microRNAs from their discovery, visualizing techniques, and relations

with human diseases to how to apply to living creatures. The first of a comprehensive portfolio

of mighty small microRNAs.”

Dr. Mikiko Siomi

Institute of Genome Research, University of Tokushima, Japan

“… an excellent collection of reviews addressing most important aspects of miRNA research,

including basics of miRNA biogenesis and function, bioinformatic approaches to target

prediction, and connection of miRNAs with human pathologies … very valuable to those already

involved in miRNA studies and to newcomers to the field.”

Professor Witold Filipowicz

Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

“… a comprehensive compilation of articles on microRNAs that span methodological,

detection, and biological implications. The well-written and thoughtful chapters in this book

offer timely contributions to our current understanding of this fast moving and exciting field.”

Dr. Kuan-Teh Jeang

Head of Molecular Virology Section, National Institutes of Health, NIAID, Bethesda, USA

“… excellent in covering not only the broad scope of the role of miRNAs in health and disease

but also the history of the discovery of miRNAs and the emerging technologies in their

computational analyses and their detection and quantitation in normal and disease tissues … an

extremely valuable resource for any scientist interested in this rapidly evolving new research area

and in developing innovative miRNA based drug discovery approaches.”

Dr. Ekkehard Leberer

Genomic Sciences, Sanofi-Aventis Pharma Gmbh, Germany

MicroR

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Appasani

Cover illustration: Whole mount chick embryo in situhybridization image indicating the expression ofmicroRNA-1 in the somatic and cardiac myotome. Imagecourtesy of Dr Diana K. Darnell and Dr Parker B. Antin of the University of Arizona.

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