rinitis alergi pada anak

Paediatrica IndonesianaVOLUME 52 NUMBER 2March

Original Article

Paediatr Indones, Vol. 52, No. 2, March 2012 61

Efficacy comparison of cetirizine and loratadine for allergic rhinitis in children

Juliana, Rita Evalina, Lily Irsa, M. Sjabaroeddin Loebis

AbstractBackgroundAllergic rhinitis represents a global health problem DIIHFWLQJWRPRUHWKDQRIWKHSRSXODWLRQZRUOGZLGH6HYHUDO VWXGLHV LQ UHFHQW \HDUV KDYH GHVFULEHG WKH HIILFDF\ RIVHFRQGJHQHUDWLRQ DQWLKLVWDPLQHV LQ \RXQJHU FKLOGUHQ ,W LVQRWZHOO HVWDEOLVKHGZKHWKHU FHWLUL]LQH LVPRUH HIIHFWLYH WKDQORUDWDGLQHLQUHGXFLQJV\PSWRPVRIDOOHUJLFUKLQLWLVObjective7KHREMHFWLYHRIWKLVVWXG\ZDVWRFRPSDUHWKHHIILFDF\RIORUDWDGLQHZLWKFHWLUL]LQHIRUWUHDWPHQWRIDOOHUJLFUKLQLWLVMethods:HFRQGXFWHGDUDQGRPL]HGGRXEOHEOLQGFRQWUROOHGWULDO RI FKLOGUHQ DJHG WR \HDUV IURP2FWREHU WR1RYHPEHU DW WZR MXQLRUKLJK VFKRROV LQ0HGDQ*URXS, UHFHLYHGPJRI FHWLUL]LQH DQG JURXS ,, UHFHLYHGPJRIORUDWDGLQH HDFKRQFHGDLO\ LQ WKHPRUQLQJ IRU GD\V'UXJHIILFDF\ZDVDVVHVVHGE\FKDQJHVIURPEDVHOLQHV\PSWRPVFRUHVDQGHYDOXDWLRQRIWKHUDSHXWLFUHVSRQVHVDIWHUGD\VGD\VDQGGD\VRIWUHDWPHQWResults 7KHHIILFDF\RIFHWLUL]LQHFRPSDUHGWRWKDWRIORUDWDGLQHZDVQRW VWDWLVWLFDOO\ VLJQLILFDQW LQGLPLQLVKLQJQDVDO V\PSWRPVDIWHUGD\VGD\VDQGGD\VRIWUHDWPHQW3 3 DQG3 UHVSHFWLYHO\(YDOXDWLRQRIVLGHHIIHFWVKRZHYHUUHYHDOHGVLJQLILFDQWO\IHZHUKHDGDFKHVLQWKHFHWLUL]LQHJURXSDIWHUGD\VDQGGD\VRIWUHDWPHQW3 DQG3 UHVSHFWLYHO\WKDQLQWKH ORUDWLGLQHJURXS,QDGGLWLRQWKH ORUDWDGLQHJURXSKDG VLJQLILFDQWO\PRUH LQVWDQFHVRISDOSLWDWLRQVDIWHUGD\VRIWUHDWPHQW3 FRPSDUHGWRWKHFHWLUL]LQHJURXSConclusion7KHUHZDVQRVLJQLILFDQWGLIIHUHQFHLQFHWLUL]LQHDQGORUDWDGLQHWUHDWPHQWHIIHFWLYHQHVVRQDOOHUJLFUKLQLWLV+RZHYHUORUDWDGLQHZDVIRXQGWRFDXVHPRUHKHDGDFKHVDQGSDOSLWDWLRQVWKDQFHWLUL]LQH[Paediatr Indones. 2012;52:61-6]

Keywords: antihistamines, cetirizine, loratadine, allergic rhinitis

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Juliana et al: (IILFDF\FRPSDULVRQRIFHWLUL]LQHDQGORUDWDGLQHIRUDOOHUJLFUKLQLWLVLQFKLOGUHQ

62Paediatr Indones, Vol. 52, No. 2, March 2012

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References

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