rf coils invivo nmr course 2014
TRANSCRIPT
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Bart van de Bank [email protected]
Ingmar Voogt [email protected]
Michel [email protected]
MR Hardware
RF Coils
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Program:2
13:30 – 14:15
MR Hardware
14:15 – 15:00
RF Coils
15:00 – 17:00
RF Practice
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Learning objectives3
After this lecture you should know:
The properties of a RF coil
The different coil types that are being used in MRI
Be able to define the coil setup suitable for your own experiments
and be able to develop a (simple) coil
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RF Coils
4
Physics (only a few)
Coil types
How to build one?
Resonance
Larmor
Principles
B1 field
Limitations
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Resonance (phenomenon)5
The ability of a system to store energy
Kinetic, electric, etc.
“Galoping Gertie”
Opened July 1940
Suspension bridge 1.6km length (3rd longest in the world)
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The bridge to MR7
0B
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Larmor equation8
0B
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9
B0Mz Z’
Y’
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10
MXY
RF Coil
Mz
ΔθZ’
Y’
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11
RF Coil
Mz
MXY
Z’
Y’
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B1 field12
Determine the strength of the B1 field.
Example:
We want to have a 90° flip for 1H MRI at 3T and the pulse will take 100 μs. What amplitude should the pulse have?
What flip angle we have if we lengthen the pulse to 400 μs?
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B1 field13
Determine the strength of the B1 field.
Example:
We want to have a 90° flip for 1H MRI at 3T and the pulse will take 100 μs. What amplitude should the pulse have?
What flip angle we have if we lengthen the pulse to 400 μs?
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Some equations14
Maxwell’s equations
Gauss’s law
Gaus’s law for magnetism
Faraday’s law
Ampere’s law (corrected)
Biot-Savart’s law*
Relation between currents and their magnetic fields.
Righthand rule
Determination of B1 Direction
* NB. approximation only at low field
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RF Coils
15
Some physics
Coil types
How to build one?
Solenoid
Surface
Helmholtz
Alderman-Grant
Bollinger
Birdcage
Arrays
Antenna’s
Microstrips
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Soleniod coil16
Benefits
Homogeneous B1-field
High B1-field strength
Drawbacks
Axial access only
B1 always perpendicular to B0
High inductance L (LF)
Source: www.hyperphysics.phy-astr.gsu.edu
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Surface (flat) coil17
Benefits
Superb SNR
Inherent localization
Drawbacks
Inhomogeneous B1-field
Limited penetration depth
Source: AJR june 2007 vol 188 no 6 1568-1572
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Helmholtz coil18
Benefits
Open access
Fairly homogeneous B1-field
Reasonable SNR
Drawbacks
Long lead conductors
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Alderman-Grant (saddle) coil19
Benefits
Volume setup
Open design
Easy to construct
Drawbacks
Inhomogeneous B1-field
Only applicable for small objects
Source: www.cis.rit.edu
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Bollinger (cosine) coil20
Benefits
Volume setup
Fairly Homogenous B1 field
Open design
Drawbacks
Complexer design
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Birdcage coil21
Benefits
Volume setup
Superb homogeneity
Applicable at high-field
Drawbacks
Very complex design
Double resonant tough
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Array coils22
Benefits
Superb SNR
Large FOV
Applicable at high-field
Applicable for parallel imaging
Drawbacks
Complex design
RF-coupling
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Antenna’s23
Benefits
(relative) Simple design
Propagating EM Wave
(poynting vector)
Combined with surface coils
Drawbacks
Only applicable at high field
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Microstrips (radiative antenna)24
Benefits
B1 directed into tissue
E-field in substrate
Very high Q
Drawbacks
Coupling in arrays
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RF Coils
25
Some physics
Coil types
How to build one?
Components
Resonance circuitry
Quality
Build your own loop coil
Geometry
Loopsize
Quality factor
Tuning
Loading
Matching
Balancing
Trapping
Quadrature
Multi nuclei
Detune
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Components & Impedance26
Inductor [H]
Impedance:
Rule of thumb: 1 nH/mm
Capacitor [F]
Impedance:
Resistor [Ω]
Impedance:
Total Impedance (=frequency profile)
circuit-dependent!
C
pF
L_coi l
nH1 2
R
ohm
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Resonance circuit27
Resonance condition:
CL1 2
C
L1 2
Serial resonance Parallel resonance
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Quality factor28
Q-factor reveals the quality of the resonant circuit
High Q Low loss or small bandwidth
Low Q High loss or high bandwidth
Frequency
30MHz 50MHz 70MHz 90MHz 100MHz
VDB(L1:2)
-10
0
10
20
30
40
50
Frequency
30MHz 50MHz 70MHz 90MHz 100MHz
VDB(L1:2)
-10
0
10
20
30
40
50
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Build your own coil I29
1. Determine loopsize
Region of interest
Target depth
2. Create loop
Determine inductance
Estimation: Rule of thumb
Determination: Use capacitor
Determine Q
Connect to system?
Not ready, yet!
Electrical Model
V_RF
R_Sy stem
50
L_Coil
nH
1
2
R_Coil
OhmT1
L_Coil
nH
1
2
R_Coil
OhmL_Coil
nH
1
2
50 R
Target (visual) depth
Optimal coil radius
2R0
Rcoil
(<<1Ω)
Inductance (L)ZL=jωL (L~1nH/mm)
(Z~300Ω @5cm, 300MHz)
Current I
High Q Low R
Q = ωL/Rcoil
P = U * I ?
[kW]
50Ω
U
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Build your own coil II30
3. Tune the loop
Larmor frequency of interest
4. Determine Q
Differentiate between
Unloaded
Loaded
5. Connect to system?
Yes
Rcoil
Current I
ZL=jωL
Electrical ModelR_Coil
OhmC_Tune
pF
L_Coil
nH
1
2
R_Coil
OhmL_Coil
nH
1
2
TUNE
ZCt=-j/ωCt
C
ω0 ω
Qunloaded = ωL/Rcoil
Tissue
(conductivity
permeability)
Rtissue
Qloaded = ω L/(Rcoil+Rtissue)
C_Tune
pF
R_Tissue
Ohm
R_Coil
OhmL_Coil
nH
1
2
Zt=?
R_Tissue
OhmC_Tune
pF
L_Coil
nH
1
2
R_Coil
Ohm
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Build your own coil III
The magic 50 ohms31
R_s ystem
50
0
R_loadn
0
V_RF
0
1
2
3
4
5
6
0 20 40 60 80 100
R [Ohm]P
[m
W]
Pow
er
R [Ω]50 Ω
RLoad < RSystem
RLoad = RSystem
RLoad > RSystem
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Build your own coil IV32
6. Match the coil
Determine total impedance)//( tissuecoilLCt RRZZZ
Electrical Model
Rcoil
Current I
ZL=jωL
TUNE
ZCt=-j/ωCt
Tissue
(conductivity
permeability)
Rtissue
Zt=?
R_Tissue
OhmC_Tune
pF
L_Coil
nH
1
2
R_Coil
Ohm
Zt=1/(1/(jωL+R)+jωC)
= a + jB
Re(Zt)=50 = a
Im(Zt)=0 ≠ B
Zt=50+jX
jB
-jB
Z_Replace
50 + jB
ω
no match
matched
50 + jB
C_Match
-jBZ_Replace
tissuecoilLC
tRRZZ
Z
11
tissuecoilLC
tissuecoilLCt
RRZZ
RRZZZ
jbaZ t
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Build your own coil V33
Tissue
(conductivity
permeability)
2Ct
2Ct Cm
2Cm
2Cm
Ct
50
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Build your own coil - summary34
Matching
C
Tuning
C
Loop
L+R
GND
Matching
Tuning
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Build your own coil
Quadrature35
I
I
-1
0
1
0
-1
0
1
0
90o
delay
+
Transmit ?
Hybride
box
Receive
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Build your own coil
Multi nuclei36
Measure different nuclei with MR
31P, 23Na, 19F, 13C etc.
Design decisions
single / multi coil arrangement
single / multi probe input
relative coil efficiency
Always need 1H coil
shimming, decoupling, localization, magnetization
transfer, multi-nuclei (time interleaved),
quantification, ...
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Build your own coil
Multi nuclei37
=
C
orL
1 2
C_HFC_LF
L_coil1 2
L_coil1 2
L_parallel1 2
L_coil1 2
C_LF
C_HF
+
@ High
Frequency
@ Low
Frequency
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Build your own coil
Detuning38
Homogeneous excitation & localized
acquisition (high SNR):
Separate Tx and Rx coil
But make sure that:
During Tx: no B1 field coupling
During Rx: no noise coupling
2C
4C
4C
L/2
L/2
Ldec
PINmatch
tune
Forward Bias
Reversed Bias
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Literature39
Haase, A., F. Odoj, et al. (2000). "NMR probeheads for in vivo
applications." Concepts in Magnetic Resonance 12(6): 361-388.
Mispelter, J., Lupu, M. & Briguet, A. NMR Probeheads for biophysical
and biomedical experiments; Imperial College Press (2006)
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Build your own coil
Workshop40
Split in 6 groups
Every group builds a coil
Practice will be in room: P59, Gebouw de Valk
(Building 304), 1st floor
Please,be very careful with the equipment
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