resting membrane potential - yonsei...
TRANSCRIPT
Cel
l Mem
bran
e Po
tent
ial
Res
ting
mem
bran
e po
tent
ial
Act
ion
(mem
bran
e) p
oten
tial
curr
ent f
low
acr
oss
the
mem
bran
e
bios
igna
l
Res
ting
Mem
bran
e Po
tent
ial
gene
sis
of re
stin
g po
tent
ial
conc
entra
tions
perm
eabi
lity
dxId
DJ
dxdVm
IZ
J
qkTD
drift
Jdi
ffusi
onJ
J K
ioo
iK
KKqkT
vv
E
Cl
KE
Eoi
io
ClCl
KK
qV kTo
iK
qVK
kT
VK
Ke
Je
qV kTN
ao
iqV
Na
kT
VN
aN
ae
Je
qV kTN
ao
iqV
Cl
kT
VC
le
Cl
Je
oC
li
Na
iK
iC
lo
Na
oK
mC
lP
Na
PK
PC
lP
Na
PK
PqkT
V
Cl
Na
KP
PP
io
Kpu
mp
KK
qkTJ
Cl
Na
KJ
JJ
KK
K
kTD
Pq
pum
pK
KK
K
dK
dvJ
JD
ZK
dxdx
Cl
Cl
Cl
Cl
dC
ldv
JD
ZC
ldx
dx
Res
ting
Mem
bran
e Po
tent
ial
Sig
nific
ant i
ons
ions
prev
ail i
n th
e in
trace
llula
r spa
ce
Act
ive
mec
hani
sms
elec
trica
l driv
ing
forc
e op
pose
sch
emic
al d
rivin
g fo
rce
limits
the
diffu
sion
al e
fflux
equi
libriu
m
Ner
nst e
quat
ion
mem
bran
e sl
ight
ly p
erm
eabl
e N
aan
d C
l
net d
rivin
g fo
rce
Gol
dman
–Hod
gkin
–Kat
z eq
uatio
n eq
uilib
rium
vol
tage
U
each
ioni
c sp
ecie
s.
Res
ting
Mem
bran
e Po
tent
ial
perm
eabi
litie
sre
stin
g st
ate
elec
tric
field
elec
trica
l for
ce
elec
troch
emic
al d
iffus
iona
l for
ce.
depl
etio
n of
iona
lgra
dien
ts
stea
dyst
ate
activ
etra
nspo
rt m
echa
nism
s
Equi
vale
nt C
ircui
t Mod
el fo
r the
Cel
l Mem
bran
eEq
uiva
lent
Circ
uit M
odel
for t
he C
ell M
embr
ane
Equi
vale
nt C
ircui
t Mod
el fo
r the
Cel
l Mem
bran
e
Neu
rons
dend
rites
rece
ptiv
e ar
eace
llula
r inp
ut
grad
ed in
puts
grad
ed p
oten
tial
cell
body
axon
nong
rade
dac
tion
pote
ntia
ls
grad
edce
llula
r out
put
Type
s of
neu
rons
Sens
ory
neur
ons
sens
ory
inpu
ts
rece
ptor
s
neur
onal
syn
apse
s
Ass
ocia
tion
neur
ons
Mot
or n
euro
nsef
fect
or o
rgan
s
Neu
rons
netw
orks
func
tion
anat
omic
al re
latio
nshi
ps
inpu
t sid
efro
m
sens
ory
rece
ptor
s fro
m o
ther
neu
rons
m
any
thou
sand
sou
tput
sid
eth
ousa
nd
task
of d
ecis
ion-
mak
ing
inpu
tsou
tput
Two
type
s of
rece
ptor
s ce
llssp
ecia
lized
sen
sory
neu
ron
bare
dend
rites
.se
nsor
ial e
ndin
gs
Prim
ary
rece
ptor
s sm
ell
nonn
euro
nalr
ecep
tor c
ell
pote
ntia
lre
cept
or p
oten
tial
Sec
onda
ry re
cept
ors
hear
ing.
exci
tabl
e ce
ll
stim
ulat
ed u uu
stim
ulat
ion
thre
shol
dsu
bthr
esho
ld s
timul
atio
n
pass
ivel
y
abov
e-th
resh
old
stim
ulat
ion
activ
ely
actio
n m
embr
ane
pote
ntia
l
actio
n im
puls
e u
u
Act
ion
Mem
bran
e Po
tent
ial
Equi
vale
nt C
ircui
t Mod
el fo
r the
Cel
l Mem
bran
eA
ctio
n M
embr
ane
Pote
ntia
lor
igin
of a
n ac
tion
pote
ntia
l st
imul
i
Arti
ficia
l exc
itatio
n
Out
war
d lo
cal c
urre
nts
Ope
ning
of g
ated
cha
nnel
s
outw
ard
curr
ents
Act
ion
Mem
bran
e Po
tent
ial