research - stony brook school of medicine - homepage | … · 2020. 1. 7. · panc ortex cortex ....
TRANSCRIPT
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Maoxin Wu, MD, PhDProfessor and Chief of Cytopathology
Research
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Overall Mission Statement
To make accurate pathological /medical diagnosis with minute sample using minimally
invasive biopsy procedure or with
non-invasive techniques
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Projects
• Funded Project (5 year grant, NIH R01)– Detection of Metastases in Lymph Nodes
Using Quantitative-Ultrasound
• General Interests:
– Molecular Marker Studies with Cytology
Samples
– Live Cell Imaging and Drug Sensitivity Testing
from Fine Needle Aspiration (FNA) Biopsy
Samples
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Detection of Metastases in
Lymph Nodes Using
Quantitative-Ultrasound
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QUS Scanning Apparatus
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3D Depiction of QUS characterized LN showing high probability of cancer in red; matching histology showing cancer foci
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Phase 1. Isolated Node Study
SBM IRB Patient Consent
LN Dissection
QUS ImagingIsolated node
H&E sectioning and reporting
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Phase 2. To use GE QUS machine to study
surgically excised specimen with lymph
nodes
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Phase 3. To use GE QUS machine to
detect metastasis in Patient’s Lymph
Nodes
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Cancer Marker Studies for
Diagnosis and Treatment using
small Cytology Samples by various
Modern Technologies
• Next Generation Sequencing (NGS)
• Fluorescent In-Situ Hybridization (FISH)
• Immunohistochemical staining (IHC)
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Live Cell Imaging and Drug Sensitivity
Testing from FNA Biopsy Samples
• http://www.essenbioscience.com/essen-
products/incucyte/?gclid=CLKWg_nEyMo
CFc4XHwodZOIK0Q