MENA EXCLUSIVE DISTRIBUTOR

MANUFACTURE

Removal of Airborne Viruses and Bacteria by the Force of Chlorine Dioxide Molecules

Preface：Possibility of a Pandemic

The Global Outbreak Alert & Response Network(2009) of WHO alerts possible pandemic diseases as follows;Anthrax, Avian influenza, Crimean-Congo hemorrhagic fever (CCHF), dengue fever , Ebola hemorrhagic fever, Hendra virus infection, Hepatitis, Influenza, 2009 influenza（H1N1）、Lassa fever, Marburg hemorrhagic fever, Meningococcal disease, Nipah virus infection, Plague, Rift Valley fever, Severe acute respiratory syndrome(SARS), Smallpox, Tularemia, Yellow fever and etcetera 19 diseases.

Every year, large number of people lives are lost due to the infectious diseases brought by various kinds of viruses in the world , These years, there have been large scale epidemics of new type influenza, Ebola , hemorrhagic fever and MERS-CoV. , Viruses that are lethally dangerous and have enormous infectiousness, could swiftly sweep worldwide and make people terrified.

Probability of New Type Influenza Virus Occurrence

Avian influenza virus

Human influenza virus

New type influenza virus

Wild aquatic bird having avian influenza virus in intestines

①contagion through contacts between birds, Infection via excrement ③two kinds viruses unite and become

a new type virus having stronger infectivity

④Fear of pandemic occurrence among human beings brought by new type virus birth

③variate to a new type virus which has from human to human infectivity

②rare contagion occurs to human by contacts, others

Relation between avian influenza virus and new type influenza virus

②rare contagion occurs to human by contacts, others

Avian influenza and swine influenza usually do not infect people , But repeatedly varying influenza virus could suddenly change to a new type influenza virus that has the ability to spread between people, which means there is the possibilities of worldwide pandemic.

What is Clean Air ?

With the power of chlorine dioxide(ClO2) molecules it removes and suppresses viruses, bacteria, fungi, allergens and odors in the airspace .

Chlorine dioxide（ClO2）

ClO2 is amazing substance for removing microbes and deodorization in airspace and make Fresh Air!!

• Removing almost of all microbes in airspace .• Effect of deodorant by ClO2 is faster and much works than Chlorine .• The deodorant effect is expected to resolute for fundamental of bad odor by chemical oxidative decomposition, It has the effect of deodorizing eight major odors of【 ammonia / methyl mercaptan / hydrogen sulfide/ methyl sulfide/ trimethylamine/ methyl disulfide/ styrene /acetaldehyde】

Mechanism of sterilizing by chlorine dioxide molecules

Viruses, bacteria, fungi & allergens , are made of

Protein

ClO2 can easily combine with amino acid molecules, of which the protein of viruses, bacteria and mold is composed, and bring the oxidative decomposition occurrence.Viruses, bacteria and mold are disinfected, when the molecule structure is changed by the oxidative decomposition with chlorine dioxide and the molecules are inactivated.

The use scene of ClO2 in the world

ClO2 is used in various fields around the world for various purposes, and important applications are used for industrial use and business use.

◆ United States (R & D is progressing from the earliest in the world)Water purification plant · · · sterilization and cleaning of tap waterDrilling of oil · · · Removal of harmful substancesFood factory, petrochemical plant · · · sterilization and cleaning

◆ China (world's largest consumption)Cleaning and sterilizing foodstuffs, drinking water removal of livestock, water treatment of factory cooling water

◆ Australia, South KoreaInfectious disease prevention of livestock .

◆ JapanCooling water · · · Legionella bacterium sterilizationPool water · · · sterilizationFood additives · · · approved as bleaching of wheat flourTap water · · · Approved for use at 2 ppm or less by purification at the water supply site by the water service methodMedical equipment · · · washing and sterilization

Safety of Chlorine dioxide (ClO2)

ClO2 is used in a tooth paste and mouth wash in the US and bleach for noodle and sanitary foods materials .The safety has been certified and guaranteed by FDA (United States Food and Drug Administration) and WHO (World Health Organization) , which have one of the world’s most stringent evaluation standards, and it has already been injected and used in water purification and pools even in USA, Canada, Europe etc. . Furthermore, it is approved in Japan for used by the Ministry of Health, Labor and Welfare for treatment of tap water and disinfection of swimming pools.

Safety of low concentration chlorine dioxide gas

Considering that end-use products of chlorine dioxide gas are being used in daily life, the Industrial Association of the Japan Society of Industrial Science and Technology has further increased tenfold of 0.1 ppm obtained by occupational health and safety , 6-month exposure test results We decided that it is necessary to provide a safe range , The indoor concentration guideline value (voluntary standard of chlorine dioxide industry association) in this case is 0.01 ppm.

Reference materials judged by Japan Chlorine Oxide Industry Association as safe

Medium to long term toxicity- Akamatsu A, Lee C, Morino H, Miura T, Ogata N, Shibata T. Six-month low level chlorine dioxide gas inhalation toxicity study with two-week recovery period in rats. J Occup Med Toxicol (2012) 7:2Human impact- Toxicological Profile for Chlorine Dioxide and Chlorite：U.S. Department of Health and Human Services Public Health Service Agency for Toxic Substances and Disease Registry September 2004Evaluation at international organizations- Occupational Health Guideline for Chlorine Dioxide：U.S. Department of Labor Occupational Safety and Health Administration September 1978- Chlorine Dioxide：ACGIH®© 2001- Toxicological Profile for Chlorine Dioxide and Chlorite：U.S. Department of Health and Human Services Public Health Service Agency for Toxic Substances and Disease Registry September 2004- Toxicological Review of Chlorine Dioxide and Chlorite：U.S. Environmental Protection Agency September 2000

Safety of Nanoclo2 Products

In Japan, the standard concentration setting criteria for chlorine dioxide gas is set at 0.01 ppm with a further 10 times safety range than 0.1 ppm according to WHO (World Health Organization) safety confirmation report※ 0.01 ppm is a value judged to be not harmful to health even if consumed over the lifetime.We are designing the product so that the emission concentration will be at around 0.01 ppm of the voluntary standard value of chlorine dioxide industry association.

【Result】After 3 hours, the emission concentration of chlorine dioxide gas is stable in the range of 0.01 ppm to 0.012 ppm

( hour )

( ppm )

※ It does not mean that it is 100% adsorbed to viruses, bacteria, fungi and odor floating in the air to change the structure. The spread of components varies depending on the use environment.

Evidence of effectiveness for nanoclo2 products

Performance evaluation test for disinfection of virus/bacteria and odor eliminating effect by Clean Air Portable typeTesting institution：Kitasato Research Center for Environmental Science （June 2002）※Each product has obtained the efficiency data against main viruses, bacteria and odor. The performance tests were conducted, by each product, under the certain conditions including safe diffusion density of chlorine dioxide gas, by a third-party institution.

※The evaluation tests were conducted for a certain viruses and bacteria, “Safe diffusion density of chlorine dioxide gas” is Indoor density guidance set by Japan Chlorine Dioxide Industry Association as a voluntary standard (JCDIA Voluntary Standards)0.01ppm

※The said tests were conducted in sealed space by rational testing methods. Because tests were not conducted in the general life environments, the result of actual usage may vary from this test result depending on the environments where it is used.

Performance evaluation test of Nanoclo2 products was conducted by a third-party testing institution

Virus・Bacteria 99％decrease！ Odor residue decreased to 0～20％ ！

<Method>In the center of test chamber inside (sealed space of 40 liter), putting one piece of product and a laboratory dish on which 4ml of virus test liquid was, after 24 hours elapsed the test liquid was measured. At the same time, in a chamber without setting the product, the same virus test liquid was measured.

Virus i<Method>In the center of test chamber inside(sealed space of 40 liter), putting one piece of product and a laboratory dish in which 4ml of virus test liquid was poured, after 24 hours elapsed the test liquid was measured. At the same time, in a chamber without setting the product, the same virus test liquid was measured.

Time TimeTime

Methyl mercaptan(garbage, excrement, sewage, halitosis, etc.)Isovaleric acid (odor of sweat, socks, pet, laundry, etc.)Trimethylamine(garbage, sewage, fishing bait, marine products processing factory, etc.)

Bacteria D Odor eliminating test

Space without the productSpace with the product

<Result>Virus i in the chamber with the product decreased by 99% after 24 hours

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Space without the productSpace with the product

<Result>Bacteria D in the chamber with the product decreased by 99% after 24 hours

Bac

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Research Result by university Hospital

Research subject：A study of ant-bacterial effect of low-concentration chlorine dioxide gas against airborne causative bacteria of nosocomial infection.

Grant-in-Aid for Scientific Research Project Research Result Report May 19, 2012Organization number ：32622Research item ： Fundamental research （C）Research period ： 2009, 2010, 2011 (3 years)Issue number ：21591299Representative researcher：Kouichirou YoshidaAssociate Professor, Showa University School of MedicineResearcher number ：50248217

We assessed the antimicrobial effect of low-concentration chlorine dioxide(ClO2) gas against airborne bacteria in an indoor environment（a medical office of Showa university(66.5 ㎥,live space)).Firstly, we calculated the number of air bone bacteria using air sampler in a medical office(control)(temperature and humidity was not controlled).And then, safe low-concentration ClO2 gas was generated in the medical office.Coming in and out at the door were not restricted. The concentration of ClO2gas was stable at 0.01ppm-0.02ppm approximately. When low-concentration ClO2 gas was generated in a room, indoor air bone bacteria were reduced compared with the control level.This antimicrobial effect of low concentration ClO2 gas was continued during the period that ClO2 gas was generated.Low concentration ClO2 gas is effective for reducing the number of air bone bacteria in a live space.

Visual test of sterilizing of the Generator ( Protective Agent )

Put a piece of bread inside transparent acrylic case, the case to make measuring fungi easier and to set up the environment and measure.

①without protective agents ② Protective agent installed

Setting conditions: indoor temperature 25 degrees,humidity 90% to 100%

Effect by Chlorine dioxide ( Mildew proof test results )

Visual test of sterilizing

Black mold begins to grow on the surface

Day 12:25 pm

Day 52:29 pm

Day 93:4 pm

Day 123:47 pm

Black mold expands at multiple Locations Blue mold occurs in plaque White fungal spores are scattered

Natural state

Protective Agent use

◆Experiment period: February 25 to March 7, 2016

Visual test of sterilizing

1. The slice of bread without protective agents1st day of research 5th day of research 9th day of research 13th day of research

5th day of the experiment: Black mold appears inside the bread slice9th day of the experiment: Blue and white spores appear on all sides of the bread slice From the 13th day of the experiment: All of the bread slice is covered in mold

Visual test of sterilizing

2. The slice of bread protected by nanoclo2 (Protective Agent)

1st day of research 5th day of research 9th day of research 13th day of research

After 13 days of the experiment, there was no visible mold on the top or sides of the bread slice. But after the 5th day mold began to appear on the bottom of the slice, where the chlorine dioxide could not reach. This confirms that chlorine dioxide (Nanoclo2 products) generated from sodium chlorine (3g) over catalysts protects against mold.

Clean Air – Portable introduction

Clean Air – Portable set

1. Since chlorine dioxide generator is reversible type with white on one side and black on the other side, you can put your favorite color for clothes etc.2. Insert a chlorine dioxide generator inside the pocket and attach the clip and wear it.

CoverageVolume

1㎥

Clean Air – Generator(Replacement set)

Effective for

60days

Economical

Pack

Product : Clean Air – Portable set

Duration : 60 days after open Generator Pack

Component : Sodium chlorite,Calcined zeoliteItems in a box : Chlorine dioxide generator,

Pocket with clip and StrapProduct Size : 100×80×8mmPackage Size : 110×170×20mm

Clean Air-Portable set Features

The new virus has no vaccine and can not be prevented at the beginning of the epidemic. However, chlorine dioxide exerts the same effect regardless of virus type.

No side effectThere is no side effect because it is not intended to inject antibodies into the body like a vaccine to make antibodies.

EconomicMedical expenses, vaccination costs, economic compared to daily mask fee.

Clean Air is The New Era of Sanitizing and deodorization

Just wear, Ease, No hassleYou do not have to go to the hospital & It's not as annoying as a mask.

Not dependent on virus type

Clean Air – Portable SET Target persons

Product Target : People who want to reduce viral infection & those who need it

■ A person with low immunity, which may become serious when infected with virusBabies , children, the elderly and their families , Patients , Pregnant women…etc.

■ A person who works at high infection rate site or a source of infection :Doctors , Nurses, pharmacist , Home care nurses, schoolteachers, Utility workers , Plane cabin crew , ambulances staff , infection control specialist , warehouses staff , Folders and document storage staff ,HVAC Workers , hygiene workers , barbers ……etc.

■ A person who is in a place susceptible to pathogens :Kindergarten, nursery school, school, hospital, waiting room, nursing home, House utilities , pharmacy , Malls , hotels , gyms , airports ,Customer service desk, Reception desk of bank or government office, cashier of supermarket…..etc.

A closed space where many people gather such as cinemas , theaters, Mosques ……..etc.

Transportation such as train, bus, taxi, plane, cars , ships .

Clean Air – Room set Introduction

Effective for

90days

Coverage Volume

13㎥

Adopt environmentally friendly eco material

ProductDurationPrincipal ComponentItems in boxProduct SizePackage Size

: Clean Air- Room set: 90 days after generator is open: Sodium chlorite ,Calcined zeolite: Chlorine dioxide generator , Eco- Case: 114×95×15mm: 110×170×20mm

We use earth-friendly non-wood "Palm Palas Caspa pulp".* Palm palm Casa pulp replaces wood pulp paper raw material. Effective utilization of non-timber can save forest resources.

Eco-Friendly

Clean Air – Room SET Target places

Product Target : Place where infection rate is high or place Where the infection may be occurred

Kindergartens, Nurseries, Schools, hospitals, Home , Utility rooms , Waiting rooms, Offices , Pharmacies , Malls , Hotels , Gyms , Airports ,Customer service desks, Reception desks in banks or government offices, Supermarkets, Cinemas , Theaters, Mosques …..etc.

We have manufacturing the know-how on top of domestic chlorine dioxide preparations. Established a technology that is safe without health hazards and releases low concentration effective for long term release effective for eradication of airborne Pathogens . Performance that is compatible with safety and effectiveness is the industry's top class.

Our wish is to be used by many people who need infection prevention. For that reason, we are committed to price, realize industry's top-class cost performance.

Considering the use according to the user 's taste and use, such as neck - and - pocket attachment with a simple design.

1.Excellent safety and sustainability

Technologies and parts related to core quality such as safety, effectiveness, sustainability are all made in Japan.

2. Made In Japan

3.Economical Price

4.Convinience & Design

Why Clean Air Product ?