reconstituting powdered medications medications that lose potency quickly in solution –are...
TRANSCRIPT
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Reconstituting Powdered Medications
• Medications that lose potency quickly in solution– are supplied in powdered form;
– are reconstituted using an appropriate diluent.
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Reconstituting Powdered Medications (cont.)
• Determine the solvent to be used to dilute medication.– Sterile water– Saline– Bacteriostatic solution
• Some meds are packaged with the appropriate solvent.
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Reconstituting Powdered Medications (cont.)
• Some medications are mixed with lidocaine.– This decreases pain on injection.
– Label or package insert indicates when lidocaine can be used.
– Must have a physician’s order to use it.
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Reconstituting Powdered Medications (cont.)
Rule 14-5Rule 14-5 To reconstitute a powdered medication:
1. find the directions;
2. use a sterile syringe and aseptic technique to draw up the diluent;
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Reconstituting Powdered Medications (cont.)
Rule 14-5Rule 14-5 (cont.)
3. inject the diluent into the medication vial;
4. agitate the mixture by rolling, inverting, or shaking the vial.
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Reconstituting Powdered Medications (cont.)
Rule 14-5Rule 14-5 (cont.)
5.make sure the powdered medication is completely dissolved.
– The solution must be free of visible particles.
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Reconstituting Powdered Medications (cont.)
• Use the specified amount of diluent.
– Too much – Dosage strength will be incorrect.
– Too little
• Powder may not dissolve completely.
• Dosage strength will be incorrect.
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Reconstituting Powdered Medications (cont.)
Rule 14-6Rule 14-6 When storing a medication after reconstitution:
1. record the date, the time of expiration, and your name or initials;
2. for multiple-dose medications, also record the solution strength.
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Reconstituting Powdered Medications (cont.)
Amount of diluent = 5 mL
Route = IV only
Diluent = 0.9% NaCl without preservatives
Instructions = shake to dissolve
Solution strength = 38 mg/mL
Storage = no refrigeration
Example Example
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Reconstituting Powdered Medications (cont.)
Ordered: Gemcitabine HCl
125 mg IVSS
On hand: see label
H = 38 mg
Q = 1 mL
D = 125 mL
Example (cont.) Example (cont.)
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Reconstituting Powdered Medications (cont.)
Step A No conversion is necessary.
Step B Calculate amount to administer using preferred method.
125 mg / 38 mg x 1 mL = A
3.29 x 1 mL = A
3.3 mL = A
Example (cont.) Example (cont.)
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Reconstituting Powdered Medications (cont.)
Step C Dose ordered (125 mg) is greater than 3 time that of dose on hand (38 mg),so 3.3 mL is reasonable.
Example (cont.) Example (cont.)
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Error Alert!
Select the correct instructions for the strength and route ordered.
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Practice
How much diluent should you add to this vial?
What are the storage instructions?Answer: 1 mL
Answer: store between 2° and 8° C
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Practice
Ordered: Synagis 75 mg IM Q8H
On hand:
What is the amount to administer?
Answer: 0.75 mL