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Page 1: Reactive Oxygen Species - MedchemExpress.com · Calycosin-7-O-β-d-glucoside showed a melanin biosynthesis ... Bioactivity: Cichoric Acid, a natural product, is reported to be antioxidative

www.MedChemExpress.com 1

Reactive Oxygen Species 

Page 2: Reactive Oxygen Species - MedchemExpress.com · Calycosin-7-O-β-d-glucoside showed a melanin biosynthesis ... Bioactivity: Cichoric Acid, a natural product, is reported to be antioxidative

Purity: 98.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg

Purity: 99.71%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg

Purity: 98.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

1 g

Purity: 98.71%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg, 50 mg, 100 mg

Purity: 99.36%Clinical Data: No Development ReportedSize: 10mM x 1mL in Water,

1 g

Purity: 99.82%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg, 25 mg

Purity: 98.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in Water,

5 g

Purity: 98.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

10 mg, 50 mg

Purity: 99.91%Clinical Data: Phase 4Size: 10mM x 1mL in DMSO,

50 mg, 100 mg

Purity: 98.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

100 mg, 1 g

Reactive Oxygen Species Inhibitors & Modulators

Bioactivity: (+)-α-Tocopherol is a vitamin E derivative. vitamin E is afat-soluble antioxidant.

Bioactivity: (-)-Epigallocatechin Gallate is a tea flavonoid with potentantioxidant, antiinflammatory, and anticarcinogenicproperties. (-)-Epigallocatechin Gallate is reported toinhibit signaling and thereby exert anticancer effects.EGFR

Bioactivity: (20S)-Protopanaxadiol (20-Epiprotopanaxadiol) is an aglyconmetabolic derivative of the protopanaxadiol-type ginsengsaponin; apoptosis inducer. IC50 value: Target: apoptosisinducer (20S)-Protopanaxadiol was used to induce cytotoxicityfor two human glioma cell lines, SF188 and U87MG. For the…

Bioactivity: (±)-Carnitine chloride exists in two isomers, known as D andL. L-carnitine plays an essential role in the β-oxidation offatty acids and also shows antioxidant, and anti-inflammatoryactivities.

Bioactivity: 1,3-Dicaffeoylquinic acid is a caffeoylquinic acid derivativethat exhibits antioxidant activity and radical scavengingactivity.

Bioactivity: 2-Phospho-L-ascorbic acid trisodium salt acts as anantioxidant and a stimulator of hepatocyte growth factor

production.(HGF)

Bioactivity: 3,5-Dicaffeoylquinic acid is a natural phenolic acid withantioxidant and anti-inflammatory activities .

Bioactivity: 3-Indolepropionic acid is shown to be a powerful antioxidantand has potential in the treatment for Alzheimer’s disease.

Bioactivity: Acetyl-11-Keto-β-Boswellic Acid (AKBA) is an activetriterpenoid compound from the extract of Boswellia serrate; anovel Nrf2 activator. IC50 value: Target: Nrf2 activator invitro: AKBA significantly reduced infarct volumes andapoptotic cells, and also increased neurologic scores by…

Bioactivity: Albiflorin is a major constituent contained in peony root;possesses therapeutic potential for neurodegenerativediseases. IC50 value: Target: in vitro: Albiflorinsignificantly ameliorated Glu-induced reduction of cellviability, nuclear and mitochondrial apoptotic alteration,…

2 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

(+)-α-Tocopherol (D-α-Tocopherol; α-Vitamin E) Cat. No.: HY-N0683

(-)-Epigallocatechin Gallate (EGCG; Epigallocatechol Gallate) Cat. No.: HY-13653

(20S)-Protopanaxadiol (20-Epiprotopanaxadiol; 20(S)-APPD) Cat. No.: HY-N0797

(±)-Carnitine chloride (DL-Carnitine chloride) Cat. No.: HY-B1453

1,3-Dicaffeoylquinic acid (1,3-O-Dicaffeoylquinic acid; 1,5-Dicaffeoylquinic acid) Cat. No.: HY-N1412

2-Phospho-L-ascorbic acid trisodium salt (L-Ascorbic acid

2-phosphate trisodium salt; …) Cat. No.: HY-107837

3,5-Dicaffeoylquinic acid (3,5-CQA; Isochlorogenic acid A) Cat. No.: HY-N0056

3-Indolepropionic acid  Cat. No.: HY-W015229

AKBA (Acetyl-11-keto-β-boswellic acid) Cat. No.: HY-N0892

Albiflorin  Cat. No.: HY-N0037

Page 3: Reactive Oxygen Species - MedchemExpress.com · Calycosin-7-O-β-d-glucoside showed a melanin biosynthesis ... Bioactivity: Cichoric Acid, a natural product, is reported to be antioxidative

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Purity: 99.50%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

2 mg, 5 mg, 10 mg, 50 mg

Purity: 99.58%Clinical Data: LaunchedSize: 10mM x 1mL in DMSO,

1 g, 5 g

Purity: 95.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

100 mg, 500 mg

Purity: 98.0%Clinical Data: LaunchedSize: 5 mg, 10 mg

Purity: 98.46%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

10 mg, 50 mg, 100 mg

Purity: 99.61%Clinical Data: LaunchedSize: 10mM x 1mL in DMSO,

100 mg, 200 mg, 500 mg

Purity: 99.88%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

2 mg, 5 mg, 10 mg, 25 mg, 50 mg

Purity: 99.80%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg, 25 mg, 50 mg, 100 mg

Purity: 98.59%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

10 mg, 25 mg, 50 mg, 100 mg

Purity: 99.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 g

 

Bioactivity: Allylthiourea is a metabolic inhibitor that selective inhibitsammonia oxidation. Target: Others Allylthiourea selectivelyinhibits ammonia oxidation at concentrations 8-80 μM.Allylthiourea (1 μM)inhibits ammonia oxidation by 80%.Complete inhibition is observed at an Allylthiourea…

Bioactivity: Alpha-mangostin is a dietary xanthone with broad biologicalactivities, such as antioxidant, anti-allergic, antiviral,antibacterial, anti-inflammatory and anticancer effects. It isan inhibitor of mutant IDH1 ( ) with a of 2.85 …IDH1-R132H Ki

Bioactivity: Amentoflavone is a natural biflavone compound with manybiological properties, including anti-inflammatory,antioxidative, and neuroprotective effects. IC50 value:Target: In vitro: In irradiated v79 cells, Pretreatment withamentoflavone 24 hours prior to 8 Gy 60Co γ-ray irradiation…

Bioactivity: Apigenin-7-glucoside exhibits significant anti-proliferativeand antioxidant activity, scavengers of ROS. In vitro:exhibits significant anti-proliferative activity againstB16F10 melanoma cells after 24 and 48 h of incubation.Apigenin-7-glucoside provoks an increase of subG0/G1, S and…

Bioactivity: Ascorbyl palmitate is an ester formed from ascorbic acid andpalmitic acid creating a fat-soluble form of vitamin C, it isalso used as an antioxidant food additive.

Bioactivity: Asiaticoside, a trisaccaride triterpene from ,Centella asiaticasuppresses signaling through inducing Smad7 andTGF-β/Smadinhibiting TGF-βRI and TGF-βRII in keloid fibroblasts;Asiaticoside shows antioxidant, anti-inflammatory, andanti-ulcer properties.

Bioactivity: Astaxanthin, a red dietary carotenoid isolated from, is an inhibitor of and aHaematococcus pluvialis PPARγ

potent antioxidant with antiproliferative, neuroprotective andanti-inflammatory activity . Astaxanthin has potential in[1]

the treatment of various diseases, such as cancers and…

Bioactivity: BD-AcAc 2, added in diet, could elevated mean blood ketonebodies of 3.5 mm and lowered plasma glucose, insulin, andleptin in animals; ketone ester given orally would delayCNS-OT seizures in rats breathing hyperbaric oxygen. IC50value: Target: a ketone ester given orally as…

Bioactivity: Benfotiamine is a synthetic S-acyl derivative of thiamine(vitamin B1); an antioxidant dietary supplement. IC50 value:Target: Benfotiamine, the lipid-soluble thiamine derivativeused as a treatment for diabetic neuropathy, can inhibit threemajor pathways(the hexosamine pathway, the advanced glycation…

Bioactivity: Bergenin, a polyphenol, is a potent antinarcotic agent withantioxidant action. IC50 value: < 2.5 μM (antiplasmodial)[3] Target: In vitro: The naloxone-precipitated withdrawalsymptom (jumping frequency) was significantly ameliorated (50%of control group) by administration of bergenin (20 mg/kg) in…

Allylthiourea (Thiosinamine; N-Allylthiourea) Cat. No.: HY-B0543

alpha-Mangostin (α-Mangostin) Cat. No.: HY-N0328

Amentoflavone (Didemethyl-ginkgetin) Cat. No.: HY-N0662

Apigenin 7-glucoside (Apigenin-7-O-β-D-glucopyranoside; Apigetrin; Cosmosiin) Cat. No.: HY-N0578

Ascorbyl palmitate (L-Ascorbic acid 6-hexadecanoate;

6-O-Palmitoyl-L-ascorbic acid) Cat. No.: HY-B0987

Asiaticoside (Madecassol) Cat. No.: HY-N0439

Astaxanthin  Cat. No.: HY-B2163

BD-AcAc 2 (Ketone Ester) Cat. No.: HY-15344

Benfotiamine (S-Benzoylthiamine O-monophosphate) Cat. No.: HY-17374

Bergenin (Cuscutin) Cat. No.: HY-N0017

Page 4: Reactive Oxygen Species - MedchemExpress.com · Calycosin-7-O-β-d-glucoside showed a melanin biosynthesis ... Bioactivity: Cichoric Acid, a natural product, is reported to be antioxidative

Purity: 95.0%Clinical Data: LaunchedSize: 10mM x 1mL in Water,

5 g

Purity: 98.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg, 25 mg

Purity: 98.0%Clinical Data: No Development ReportedSize: 100 mg, 200 mg, 500 mg, 1 g, 5 g

Purity: 99.95%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

10 mg, 25 mg, 50 mg

Purity: 99.29%Clinical Data: Phase 3Size: 10mM x 1mL in DMSO,

500 mg

Purity: 98.0%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 50 mg, 100 mg

Purity: 98.71%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

10 mg, 50 mg

Purity: 99.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

1 g

Purity: 98.93%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg

Purity: 99.91%Clinical Data: LaunchedSize: 10mM x 1mL in DMSO,

5 g, 10 g

 

Bioactivity: Bromhexine Hydrochloride is a medication prescribed for coughswhich works by dissolving hard phlegm. Target: OthersBromhexine is a mucolytic agent used in the treatment ofrespiratory disorders associated with viscid or excessivemucus. In addition, bromhexine has antioxidant properties.…

Bioactivity: Bufotalin is a cardiotoxic bufanolide steroid, cardiacglycoside analogue, secreted by a number of toad species; anovel anti-osteoblastoma agent. IC50 value: Target: in vitro:bufotalin induced osteoblastoma cell death and apoptosis indose- and time-dependent manners. Further, bufotalin induced…

Bioactivity: Butylhydroxyanisole is an antioxidant, consisting of a mixtureof two isomeric organic compounds, used as a food additivepreservative

Bioactivity: Calycosin-7-O-β-D-glucoside, a melanin biosynthesis inhibitor,is isolated from the methanol extract of astragalus. IC50value: 68 μM in inhibition of Tyrosinase Target: In vitro:Calycosin-7-O-β-d-glucoside showed a melanin biosynthesisinhibition zone in a culture plate of Streptomyces…

Bioactivity: Canthaxanthin is a red-orange carotenoid with variousbiological activities, such as antioxidant, antitumorproperties.

Bioactivity: Chlorogenic acid is a major phenolic compound in coffee andtea. It plays several important and therapeutic roles such asantioxidant activity, antibacterial, hepatoprotective,cardioprotective, anti-inflammatory, antipyretic,neuroprotective, anti-obesity, antiviral, anti-microbial,…

Bioactivity: Cichoric Acid, a natural product, is reported to beantioxidative.

Bioactivity: Coenzyme Q10 is an essential cofactor of the electrontransport chain and a potent antioxidant agent.

Bioactivity: Cynarin is an antichoke agent with a variety of biologicalactivities including antioxidant, antihistamic and antiviralactivities.

Bioactivity: Cysteamine is an agent for the treatment of nephropathiccystinosis and an antioxidant. Target: Others Cysteamine hasbeen shown to increase intracellular glutathione levels incystinotic cells, thus restoring the altered redox state ofthe cells. Also increased rates of apoptosis in cystinotic…

4 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Bromhexine hydrochloride  Cat. No.: HY-B0372A

Bufotalin  Cat. No.: HY-N0878

Butylhydroxyanisole (Butylated hydroxyanisole; BHA; E320) Cat. No.: HY-B1066

Calycosin-7-O-β-D-glucoside  Cat. No.: HY-N0520

Canthaxanthin (E 161g; all-trans-Canthaxanthin) Cat. No.: HY-B1960

Chlorogenic acid (3-O-Caffeoylquinic acid; Heriguard; NSC-407296) Cat. No.: HY-N0055

Cichoric Acid (Cichoric acid; Dicaffeoyltartaric acid) Cat. No.: HY-N0457

Coenzyme Q10 (Ubiquinone-10; CoQ10) Cat. No.: HY-N0111

Cynarin (Cynarine) Cat. No.: HY-N0359

Cysteamine (β-Mercaptoethylamine; 2-Aminoethanethiol;

2-Mercaptoethylamine) Cat. No.: HY-77591A

Page 5: Reactive Oxygen Species - MedchemExpress.com · Calycosin-7-O-β-d-glucoside showed a melanin biosynthesis ... Bioactivity: Cichoric Acid, a natural product, is reported to be antioxidative

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Purity: 98.0%Clinical Data: Phase 3Size: 10mM x 1mL in DMSO,

50 mg

Purity: 99.94%Clinical Data: Phase 3Size: 10mM x 1mL in DMSO,

50 mg

Purity: 98.08%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg

Purity: 99.52%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg, 50 mg

Purity: 99.58%Clinical Data: Phase 3Size: 5 mg, 10 mg, 50 mg, 100 mg

Purity: 98.0%Clinical Data: Phase 3Size: 10mM x 1mL in Water,

10 mg, 50 mg, 100 mg

Purity: 99.15%Clinical Data: LaunchedSize: 10mM x 1mL in DMSO,

1 g, 5 g

Purity: 98.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in Water,

10 mg, 25 mg, 50 mg, 100 mg

Purity: 98.0%Clinical Data: No Development ReportedSize: 5 g

Purity: 98.0%Clinical Data: LaunchedSize: 10mM x 1mL in DMSO,

5 g

 

Bioactivity: Cysteamine Hydrochloride is an agent for the treatment ofnephropathic cystinosis and an antioxidant. Target: OthersCysteamine has been shown to increase intracellularglutathione levels in cystinotic cells, thus restoring thealtered redox state of the cells. Also increased rates of…

Bioactivity: D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that iscapable of metal chelating, moisturizing and antioxidantactivity.

Bioactivity: D-alpha-Hydroxyglutaric acid disodium salt is a weakcompetitive α-Ketoglutarate( )-dependent dioxygenaseα-KGinhibitor with of 10.87±1.85 mM. K for L-HydroxyglutaricKi iacid (L-2-HG) is 0.628±0.036 mM.

Bioactivity: Dapsone is a sulfone active against a wide range of bacteriabut mainly employed for its actions against mycobacteriumleprae. Target: Antibacterial Dapsone is an antibacterial mostcommonly used in combination with rifampicin and clofazimineas multidrug therapy (MDT) for the treatment of Mycobacterium…

Bioactivity: Disufenton sodium (NXY-059) is the disulfonyl derivative ofthe neuroprotective spin trap phenylbutynitrone(PBN), bothNXY-059, its parent PBN and their hydrolysis/oxidation productMNT are very powerful scavengers of free radicals. IC50 value:Target: Neuroprotectant in vitro: Disufenton sodium is more…

Bioactivity: Ebselen is a small-molecule capsid Inhibitor of HIV-1replication. Target: Ebselen is an organoselenium compound, asan inhibitor of HIV-1 capsid CTD dimerization. Ebseleninhibits early viral postentry events of the HIV-1 life cycleby impairing the incoming capsid uncoating process. [1]…

Bioactivity: Echinacoside is a natural polyphenolic compound, has variouskinds of pharmacological activities, such as antioxidative,anti-inflammatory, neuroprotective, hepatoprotective, nitricoxide radical-scavenging and vasodilative ones. IC50 value:Target: in vitro: Echinacoside(ECH) dose dependently inhibited…

Bioactivity: Echinocystic acid a pentacyclic triterpene isolated from thefruits of Gleditsia sinensis Lam, has potent antioxidant,anti-inflammatory and anti-tumor properties. In vitro:Echinocystic acid (EA) inhibit the formation of osteoclast. EAinhibit RANKL-induced NF-κB activation and ERK phosphorylation…

Bioactivity: Efaproxiral is a synthetic allosteric modifier of haemoglobin(Hb), decreases Hb-oxygen (O2) binding affinity and enhancesoxygenation of hypoxic tumours during radiation therapy. invitro: Efaproxiral increases oxygen levels in hypoxic tumortissues by binding non-covalently to the hemoglobin tetramer…

Bioactivity: Efaproxiral sodium is a synthetic allosteric modifier ofhaemoglobin (Hb), decreases Hb-oxygen (O2) binding affinityand enhances oxygenation of hypoxic tumours during radiationtherapy. in vitro: Efaproxiral increases oxygen levels inhypoxic tumor tissues by binding non-covalently to the…

Cysteamine hydrochloride (β-Mercaptoethylamine Hydrochloride;

2-Aminoethanethiol Hydrochloride; …) Cat. No.: HY-77591

D-(+)-Glucono-1,5-lactone (Gluconic acid lactone) Cat. No.: HY-I0301

D-alpha-Hydroxyglutaric acid disodium salt (Disodium (R)-2-hydroxyglutarate) Cat. No.: HY-100542

Dapsone (4,4′-Diaminodiphenyl sulfone; DDS) Cat. No.: HY-B0688

Disufenton sodium (NXY-059) Cat. No.: HY-13244

Ebselen (SPI-1005; PZ-51; CCG-39161) Cat. No.: HY-13750

Echinacoside  Cat. No.: HY-N0020

Echinocystic acid  Cat. No.: HY-N0271

Efaproxiral (RSR13) Cat. No.: HY-13619

Efaproxiral sodium (RSR13 sodium) Cat. No.: HY-13619A

Page 6: Reactive Oxygen Species - MedchemExpress.com · Calycosin-7-O-β-d-glucoside showed a melanin biosynthesis ... Bioactivity: Cichoric Acid, a natural product, is reported to be antioxidative

Purity: 99.07%Clinical Data: No Development ReportedSize: 10mM x 1mL in Water,

5 mg, 10 mg

Purity: 99.98%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

10 mg

Purity: 99.97%Clinical Data: LaunchedSize: 10mM x 1mL in DMSO,

100 mg, 500 mg

Purity: 99.74%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

1 g, 5 g

Purity: 99.86%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

100 mg, 500 mg

Purity: 99.14%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

100 mg

Purity: 98.05%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

1 g

Purity: 99.60%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg

Purity: 99.56%Clinical Data: LaunchedSize: 10mM x 1mL in DMSO,

100 mg, 500 mg

Purity: 99.92%Clinical Data: Phase 2Size: 1 g, 5 g

 

Bioactivity: Ellagic acid is a natural antioxidant, and acts as a potentand ATP-competitive inhibitor, with an of 40 nM andCK2 IC50a of 20 nM.Ki

Bioactivity: Emeramide is a novel lipid-soluble, thiol-redox antioxidantand heavy metal chelator.

Bioactivity: Epiberberine chloride is an alkaloid isolated from Coptis, acts as a potent and inhibitor, and achinensis AChE BChE

non-competitive inhibitor, with s of 1.07, 6.03 andBACE1 IC508.55 μM, respectively. Epiberberine chloride has antioxid…

Bioactivity: Ethoxyquin is an antioxidant which has been used in animalfeed for many years and also an inhibitor of heat shock

( ).protein 90 Hsp90

Bioactivity: Ethyl ferulate, a naturally lipophilic derivative of ferulicacid originally derived from giant fennel ( ),F. communisinduces heme oxygenase-1 (HO-1) and protects rat neuronsagainst oxidative stress . Ethyl ferulate also protects[1]

neurons against amyloid β peptide (1-42)-induced oxidative…

Bioactivity: Eugenol is an essential oil found in cloves withantibacterial, anthelmintic and antioxidant activity. Eugenolis shown to inhibit lipid peroxidation.

Bioactivity: Ferulic acid (4-hydroxy-3-methoxycinnamic acid) is a phenoliccompound present in several plants with claimed beneficialeffects in prevention and treatment of disorders linked tooxidative stress and inflammation. IC50 value: Target: 5-HTReceptor In vitro: In the present study we have showed that…

Bioactivity: Gallic acid is an antioxidant which can inhibit both .COX-2

Bioactivity: Glabridin is a natural isoflavan from , bindsGlycyrrhiza glabrato and activates , with an of 6115 nM. GlabridinPPARγ EC50exhibits antioxidant, anti-bacterial, anti-nephritic,anti-diabetic, anti-fungal, antitumor, anti-inflammatory,antiosteoporotic, cardiovascular protective, neuroprotective…

Bioactivity: Glucoraphanin, a natural glucosinolate found in cruciferousvegetable, is a stable precursor of the Nrf2 inducersulforaphane, which possesses antioxidant, anti-inflammatory,and anti-carcinogenic effects.

6 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Ellagic acid  Cat. No.: HY-B0183

Emeramide (BDTH2) Cat. No.: HY-16739

Epiberberine chloride  Cat. No.: HY-N0226A

Ethoxyquin  Cat. No.: HY-B1425

Ethyl ferulate  Cat. No.: HY-N0061

Eugenol  Cat. No.: HY-N0337

Ferulic acid sodium (Sodium ferulate) Cat. No.: HY-N0060A

Gallic acid (3,4,5-Trihydroxybenzoic acid) Cat. No.: HY-N0523

Glabridin  Cat. No.: HY-N0393

Glucoraphanin  Cat. No.: HY-N4068

Page 7: Reactive Oxygen Species - MedchemExpress.com · Calycosin-7-O-β-d-glucoside showed a melanin biosynthesis ... Bioactivity: Cichoric Acid, a natural product, is reported to be antioxidative

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Purity: 99.97%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

10 mg, 50 mg, 100 mg

Purity: 99.65%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

10 mg, 50 mg, 100 mg

Purity: >98%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg, 50 mg, 100 mg

Purity: >98%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg, 50 mg, 100 mg

Purity: 98.58%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg

Purity: 98.02%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

100 mg, 500 mg, 1 g, 5 g

Purity: 97.00%Clinical Data: Phase 3Size: 10mM x 1mL in DMSO,

10 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g

Purity: 99.82%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

50 mg

Purity: 98.30%Clinical Data: No Development ReportedSize: 10mM x 1mL in Water,

100 mg

Purity: 98.0%Clinical Data: LaunchedSize: 10mM x 1mL in Water,

50 mg

 

Bioactivity: Glucosamine (hydrochloride) is a natural product. IC50 value:Target: In vitro: Glucosamine hydrochloride exhibiteddose-dependent DPPH antioxidant activity [1]. Short-term (4 h)glucosamine hydrochloride treatment inhibited HIF-1α at theprotein level, decreased phosphorylation of p70S6K and S6,…

Bioactivity: Glutathione oxidized is produced by the oxidation ofglutathione which is a major intracellular antioxidant anddetoxifying agent.

Bioactivity: H2DCFDA is a cell-permeable probe used to detect intracellular.reactive oxygen species (ROS)

Bioactivity: Hesperidin (HP) is a bioflavonoid that plays a role in plantdefense and is abundant in citrus species, such as grapefruit,lemon and orange. Hesperidin is used effectively as asupplemental agent in complementary therapy protocols, sinceit possesses biological and pharmacological properties as an…

Bioactivity: Hexaconazole is a systemic fungicide used for the control ofmany fungi particularly Ascomycetes and Basidiomycetes. Invitro: Among the enzymatic antioxidants, superoxide dismutaseand peroxidase are significantly up-regulated by hexaconazole.[1] Hexaconazole and its enantiomers cause the down-regulation…

Bioactivity: Hexahydrocurcumin is a natural compound which posessesanticancer and anti-inflammatory activities; selective COX-2inhibitor. IC50 value: Target: in vitro: The relativeantioxidant potencies of ginger compounds decreased in similarorder of 1-dehydro-[6]-gingerdione,…

Bioactivity: HO-1-IN-1 (Compound 2) is a heme oxygenase 1 ( )HO-1inhibitor with an of 250 nM .IC50

[1]Bioactivity: HO-1-IN-1 hydrochloride (Compound 2) is a heme oxygenase 1 (

) inhibitor with an of 250 nM .HO-1 IC50[1]

Bioactivity: HTHQ, which is a hydroquinone monoalkyl ether, is a potentanti-oxidative agent, even at low dose levels. HTHQ is foundto be a potent anti-lipid-peroxidative compound and itsantioxidation activity to be extremely elevated in biologicalsystems, such as that of liver microsomes via the generation…

Bioactivity: Isoquercitrin is an effective antioxidant and an eosinophilicinflammation suppressor.

Glucosamine hydrochloride (D-(+)-Glucosamine hydrochloride;

Chitosamine hydrochloride) Cat. No.: HY-N0733

Glutathione oxidized (L-Glutathione oxidized; GSSG) Cat. No.: HY-D0844

H2DCFDA (DCFH-DA; 2',7'-Dichlorodihydrofluorescein diacetate) Cat. No.: HY-D0940

Hesperidin (Hesperetin 7-rutinoside) Cat. No.: HY-15337

Hexaconazole ((-)-Hexaconazol) Cat. No.: HY-A0278

Hexahydrocurcumin  Cat. No.: HY-N0929

HO-1-IN-1  Cat. No.: HY-111798

HO-1-IN-1 hydrochloride  Cat. No.: HY-111798A

HTHQ (1-O-hexyl-2,3,5-trimethylhydroquinone) Cat. No.: HY-100768

Isoquercitrin (Isoquercitroside; Isoquercetin) Cat. No.: HY-N0768

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Purity: 99.88%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg

Purity: 98.07%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg, 25 mg, 50 mg, 100 mg

Purity: 99.59%Clinical Data: Phase 4Size: 10mM x 1mL in DMSO,

500 mg

Purity: 95.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg

Purity: 98.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in Water,

5 mg, 10 mg, 50 mg

Purity: 99.78%Clinical Data: LaunchedSize: 10mM x 1mL in DMSO,

10 mg, 50 mg, 100 mg, 200 mg

Purity: 99.83%Clinical Data: No Development ReportedSize: 1 g, 5 g

Purity: 98.0%Clinical Data: Phase 4Size: 10mM x 1mL in Water,

1 g

Purity: 99.89%Clinical Data: LaunchedSize: 10mM x 1mL in Water,

1 g

Purity: 98.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg

 

Bioactivity: Isosteviol is a derivative of stevioside, a constituent ofStevia rebaudiana, which is commonly used as a noncaloricsugar substitute in Japan and Brazil. Target: Isostevioldose-dependently relaxed the vasopressin (10-8 M)-inducedvasoconstriction in isolated aortic rings with or without…

Bioactivity: L-Ascorbic acid is an effective reducing agent and donorantioxidant.

Bioactivity: L-Ascorbic acid (sodium) is a more bioavailable form ofvitamin C that is an antioxidant agent.

Bioactivity: L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine)is an endogenous antioxidant and is capable of scavengingoxygen-derived free radicals.

Bioactivity: Lacidipine (Lacipil, Motens) is a L-type calcium channelblocker. Target: Calcium Channel Lacidipine, a novelthird-generation dihydropyridine calcium channel blocker, hasbeen demonstrated effective for hypertension. lacidipineprotects HKCs against apoptosis induced by ATP depletion and…

Bioactivity: Levomefolic acid (5-MTHF) is the natural, active form of folicacid used at the cellular level for DNA reproduction, thecysteine cycle and the regulation of homocysteine among otherfunctions. IC50 value: Target: Folate analog Levomefolic acidhas been proposed for treatment of cardiovascular disease and…

Bioactivity: Limonene is a monoterpene in citrus peel oil. A populardisinfectant and food preservative. Antimicrobial activities

. Anti-proliferative activities . Antioxidant and[1] [2]

anti-inflammatory effect .[3]

Bioactivity: Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, whichis an essential cofactor of enzyme complexes.mitochondrial(R)-(+)-α-Lipoic acid is more effective than racemic Lipoicacid.

Bioactivity: Liquiritin is a flavonoid isolated from , acts as anGlycyrrhizaantioxidant and has neuroprotective, anti-cancer andanti-inflammatory activity .[1] [2]

Bioactivity: Lobetyolin is derived from and hasCodonopsis pilosulaantioxidative effect.

8 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Isosteviol ((-)-Isosteviol; iso-Steviol) Cat. No.: HY-N0872

L-Ascorbic acid (L-Ascorbate; Vitamin C) Cat. No.: HY-B0166

L-Ascorbic acid sodium salt ((+)-Sodium L-ascorbate; Vitamin

C sodium salt; Sodium L-ascorbate) Cat. No.: HY-B0166A

L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) Cat. No.: HY-D0187

Lacidipine  Cat. No.: HY-B0347

Levomefolic acid (5-MTHF) Cat. No.: HY-14781

Limonene  Cat. No.: HY-N0544

Lipoic acid ((R)-(+)-α-Lipoic acid; R-(+)-Thioctic acid) Cat. No.: HY-18733

Liquiritin  Cat. No.: HY-N0376

Lobetyolin  Cat. No.: HY-N0327

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Purity: 99.57%Clinical Data: LaunchedSize: 10mM x 1mL in DMSO,

10 mg, 50 mg

Purity: 98.22%Clinical Data: LaunchedSize: 100 mg, 500 mg, 1 g

Purity: 98.72%Clinical Data: Phase 1Size: 10mM x 1mL in DMSO,

100 mg, 500 mg, 1 g, 5 g

Purity: 99.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

1 mg, 5 mg

Purity: 98.0%Clinical Data: Phase 4Size: 5 mg, 10 mg, 25 mg, 50 mg

Purity: 98.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

1 g

Purity: 99.96%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 g

Purity: 98.14%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

50 mg, 100 mg, 200 mg, 500 mg

Purity: 98.0%Clinical Data: Phase 4Size: 5 mg, 10 mg, 25 mg, 50 mg

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg, 10 mg

 

Bioactivity: Luciferase from has also been used in a study toVibrio fischeriinvestigate the sensitivity of dark mutants of various strainsof luminescent bacteria to reactive oxygen species.

Bioactivity: Lycopene is naturally occurring carotenoids found in tomato,tomato products, and in other red fruits and vegetables;exhibits antioxidant effects.

Bioactivity: 1-Methoxy PMS is stable electron-transport mediator betweenNAD(P)H and tetrazolium dyes. 1-Methoxy PMS can induce activeoxygen formation.

Bioactivity: Methyl gallate is a plant phenolic with antioxidant,anticancer, and anti-inflammatory activities. Methyl gallatealso shows inhibition activity.bacterial

Bioactivity: Methyl vanillate, one of the ingredients in Hovenia dulcisThunb, is a pathway activator . AWnt/β-catenin [1]

benzoate ester that is the methyl ester of vanillic acid. Ithas a role as an antioxidant and a plant metabolite.

Bioactivity: Mitoquinone mesylate is a TPP-based, mitochondriallytargeted antioxidant.

Bioactivity: N-Acetylcysteine amide is a cell membranes and blood brainbarrier permeant thiol antioxidant and neuroprotective agent.

Bioactivity: Naringenin is the predominant flavanone in grapefruit;displays strong anti-inflammatory and antioxidant activities.

Bioactivity: Nisoldipine(BAY-k 5552; Sular) is a calcium channel blockerbelonging to the dihydropyridines class, specific for L-typeCav1.2 with IC50 of 10 nM. IC50 value: 10 nM Target: L-typeCav1.2 Nisoldipine is a potent blocker of L-type calciumchannels. Nisoldipine binds directly to inactive calcium…

Bioactivity: Nitisinone(SC0735) is an inhibitor of the enzyme4-hydroxyphenylpyruvate dioxygenase. Target:4-Hydroxyphenylpyruvate Dioxygenase Nitisinone is a drug usedto slow the effects of hereditary tyrosinemia type 1.Nitisinone reduced urinary HGA levels from an average of 4.0…

Luciferase  Cat. No.: HY-P1004

Lycopene  Cat. No.: HY-N0287

Methoxy-PMS (1-Methoxy PMS; 1-Methoxyphenazine methosulfate) Cat. No.: HY-D0937

Methyl gallate (Gallincin; NSC 363001) Cat. No.: HY-N2010

Methyl vanillate  Cat. No.: HY-75342

Mitoquinone mesylate (Mitoquinone methanesulfonate; MitoQ10

mesylate; MitoQ mesylate) Cat. No.: HY-100116A

N-Acetylcysteine amide  Cat. No.: HY-110256

Naringenin  Cat. No.: HY-N0100

Nisoldipine (BAY-k 5552) Cat. No.: HY-17402

Nitisinone (NTBC; Nitisone; SC0735) Cat. No.: HY-B0607

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Purity: 99.12%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg, 50 mg, 100 mg

Purity: 98.04%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

10 mg, 50 mg

Purity: 99.92%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

100 mg

Purity: 99.40%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

1 mg, 5 mg, 10 mg, 25 mg

Purity: 99.19%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

10 mg

Purity: 99.26%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg, 25 mg

Purity: 98.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg

Purity: 99.96%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

1 g

Purity: 99.52%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg

Purity: 99.86%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg

 

Bioactivity: OBA-09 is a novel multimodal neuroprotectant oxopropanoyloxybenzoic acid (a salicylic acid/pyruvate ester); shows robustprotective effects in the postischemic brain. IC50 value:Target: OBA-09 exhibited antioxidative effects in thepostischemic brain, which was evidenced by remarkable…

Bioactivity: Octahydrocurcumin is a hydrogenated derivatives of curcumin;metabolite of curcumin. IC50 value: Target: OKT3-induced PBMCproliferation was inhibited by octahydrocurcumin with IC50 of82 uM. The investigated substances with the strongest effecton radical scavenging were tetrahydro-, hexahydro-, and…

Bioactivity: Octyl gallate (Progallin O) is widely used as a food additive,with antimicrobial and antioxidant activity . Octyl[1] [2]

gallate (Progallin O) shows selective and sensitivefluorescent property .[2]

Bioactivity: Phillygenin is an active ingredient from Forsythia with manymedicinal properties, such as antioxidant, reducing bloodlipid, inhibition of low density lipoprotein oxidation. Invitro : 1) Phillygenin shows a greater inhibition on mouse B16melanoma cells potential than vincristine. 2) phillygenin had…

Bioactivity: Pinocembrin ((+)-Pinocoembrin) is a flavonoid found inpropolis, acts as a competitive inhibitor of histidine

, and is an effective anti-allergic agent, withdecarboxylaseantioxidant, antimicrobial and anti-inflammatory properties

.[1]

Bioactivity: Piperlongumine is a natural alkaloid isolated from Piper Linn , possesses ant-inflammatory,longum [1]

antibacterial, antiangiogenic, antioxidant, antitumor, andantidiabetic activities . Piperlongumine induces ROS, …[2]

Bioactivity: Procyanidin B2 is a natural flavonoid, with anti-cancer,antioxidant activities.

Bioactivity: Protocatechualdehyde (Catechaldehyde), a natural polyphenolcompound isolated from the roots of radix Salviae

, is associated with a wide variety ofMiltiorrhizaebiological activities and has been widely used in medicine asan antioxidant, anti-aging, an antibacterial and…

Bioactivity: Protopine, an isoquinoline alkaloid contained in plants innortheast Asia. IC50 Value: Target: In vitro: Protopine wasfound to reduce nitric oxide (NO), cyclooxygenase-2 (COX-2),and prostaglandin E(2) (PGE(2)) production by LPS-stimulatedRaw 264.7 cells, without a cytotoxic effect. Pre-treatment of…

Bioactivity: Quercitrin is a natural compound found in Tartary buckwheatwith a potential anti-inflammation effect that is used totreat heart and vascular conditions. IC50 value: Target: Invitro: There were significant increases in caspase-3 activity,loss of MMP, and increases in the apoptotic cell population in…

10 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

OBA-09  Cat. No.: HY-12840

Octahydrocurcumin (Hexahydrobisdemethoxycurcumin) Cat. No.: HY-N0894

Octyl gallate (n-Octyl gallate; Stabilizer GA 8) Cat. No.: HY-N2011

Phillygenin (Phillygenol; Epipinoresinol methyl ether;

(+)-Phillygenin) Cat. No.: HY-N0483

Pinocembrin ((+)-Pinocoembrin; Dihydrochrysin; Galangin flavanone) Cat. No.: HY-N0575

Piperlongumine (Piplartine) Cat. No.: HY-N2329

Procyanidin B2 (Proanthocyanidin B2) Cat. No.: HY-N0796

Protocatechualdehyde (Catechaldehyde; Protocatechuic aldehyde; Rancinamycin IV) Cat. No.: HY-N0295

Protopine (Corydinine) Cat. No.: HY-N0793

Quercitrin (Quercetin 3-rhamnoside) Cat. No.: HY-N0418

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Purity: 98.32%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

10 mg, 25 mg, 50 mg, 100 mg, 200 mg

Purity: 98.0%Clinical Data: LaunchedSize: 10mM x 1mL in DMSO,

100 mg, 500 mg

Purity: 99.95%Clinical Data: Phase 2Size: 10mM x 1mL in Water,

5 mg, 10 mg, 25 mg, 50 mg, 100 mg

Purity: 99.99%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

10 mg, 50 mg

Purity: 99.0%Clinical Data: LaunchedSize: 10mM x 1mL in DMSO,

100 mg

Purity: 95.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in Water,

100 mg

Purity: 98.0%Clinical Data: LaunchedSize: 10mM x 1mL in DMSO,

5 g, 10 g

Purity: 98.56%Clinical Data: LaunchedSize: 10mM x 1mL in DMSO,

100 mg

Purity: 99.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

100 mg, 200 mg, 500 mg

Purity: 97.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg, 25 mg, 50 mg

 

Bioactivity: Reynoutrin (Quercetin-3-D-xyloside) is a flavonoid from, with antioxidant andPsidium cattleianum

radical-scavenging activity .[1]

Bioactivity: Rhein is a lipophilic anthraquinone extensively found inmedicinal herbs, and has many pharmacological effects,including epatoprotective, nephroprotective,anti-inflammatory, antioxidant, anticancer, and antimicrobialactivities. IC50 value: Target: In vitro: Rhein (0.1 and 1…

Bioactivity: Riboflavin tetrabutyrate is a lipophilic flavin derivativewith antioxidative and lipid peroxide-removing activity.

Bioactivity: Rutin, a naturally occurring flavonoid glycoside, hasantioxidant, anti-inflammatory, anti-allergic, anti-angiogenicand antiviral properties.

Bioactivity: S-Methyl-L-cysteine is a natural product that acts as asubstrate in the catalytic antioxidant system mediated bymethionine sulfoxide reductase A (MSRA), with antioxidative,neuroprotective, and anti-obesity activities.

Bioactivity: Salsalate is a nonsteroidal anti-inflammatory drug (NSAID).Target Salsalate is a medication that belongs to thesalicylate and non-steroidal anti-inflammatory drug (NSAID)classes. Relative to other NSAIDs, Salsalate has a weakinhibitory effect on the cyclooxygenase enzyme and decreases…

Bioactivity: Schisandrin B(Wuweizisu-B) is a dibenzocyclooctadienederivative isolated from Fructus Schisandrae, has been shownto produce antioxidant effect on rodent liver and heart. IC50value: Target: in vitro: Schisandrin B exhibitsanti-inflammatory activity through modulation of the…

Bioactivity: Secoisolariciresinol diglucoside (SDG; LGM2605) is a non-toxicfree radical scavenger and antioxidant, reduces reduces ROSgeneration. Secoisolariciresinol diglucoside enhancesactivatation Nrf2 signaling, inhibits myeloperoxidase

.(MPO)

Bioactivity: Silibinin, an effective anti-cancer and chemopreventive agent,has been shown to exert multiple effects on cancer cells,including inhibition of both cell proliferation and migration.IC50 value: Target: anticancer in vitro: silibininsignificantly induced the expression of the non-steroidal…

Bioactivity: Sinapine is an alkaloid from seeds of the cruciferous specieswhich shows favorable biological activities such asantioxidant and radio-protective activities.

Reynoutrin (Quercetin-3-D-xyloside; Reinutrin) Cat. No.: HY-N1354

Rhein (Rheic Acid; Rhubarb yellow; Monorhein) Cat. No.: HY-N0105

Riboflavin Tetrabutyrate  Cat. No.: HY-B2239

Rutin (Rutoside; Quercetin 3-O-rutinoside) Cat. No.: HY-N0148

S-Methyl-L-cysteine (L-S-Methylcysteine) Cat. No.: HY-B2188

Salsalate (Salicylsalicylic acid; Disalicylic acid) Cat. No.: HY-B1245

Schisandrin B (Schizandrin-B; Wuweizisu-B; gamma-Schisandrin) Cat. No.: HY-N0089

Secoisolariciresinol diglucoside (SDG; LGM2605) Cat. No.: HY-105008

Silibinin (Silybin; Silibinin A; Silymarin I) Cat. No.: HY-13748

Sinapine thiocyanate  Cat. No.: HY-N0450

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Purity: 99.0%Clinical Data: No Development ReportedSize: 1 g

Purity: 99.12%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg

Purity: 99.53%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

500 mg, 1 g, 5 g

Purity: 99.72%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

50 mg

Purity: 95.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

100 mg

Purity: 99.56%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

50 mg, 100 mg

Purity: 99.97%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg, 25 mg, 50 mg, 100 mg

Purity: 98.0%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg

Purity: 99.95%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg

Purity: 99.61%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

100 mg

 

Bioactivity: Sinapinic acid (Sinapic acid) is a phenolic compound isolatedfrom Jack. Rhizome, acts as anHydnophytum formicaruminhibitor of , with an of 2.27 mM , and alsoHDAC IC50

[1]

inhibits activity . Sinapinic acid posssess pot…ACE-I [2]

Bioactivity: Sodium formononetin-3'-sulfonate (Sul-F) is a water-sol.derivate of formononetin. IC50 value: Target: Research resultsshowed that treatment with Sul-F significantly prevented theelevation of ST-segment level, decreased the contents ofcreatine kinase-MB, lactate dehydrogenase, alanine…

Bioactivity: Squalene is an intermediate product in the synthesis ofcholesterol, and shows several pharmacological properties suchas hypolipidemic, hepatoprotective, cardioprotective,antioxidant, and antitoxicant activity.

Bioactivity: Succinobucol is a phenolic antioxidant with anti-inflammatoryand antiplatelet effects.

Bioactivity: Sulcotrione is a β-triketone herbicide which can inhibit ( ).hydroxyphenylpyruvate dioxygenase HPPD

Bioactivity: Tetrahydroxyquinone is a molecule best known as a primitiveanticataract drug, is also a highly redox active molecule thatcan take part in a redox cycle with semiquinone radicals,leading to the formation of reactive oxygen species (ROS).

Bioactivity: Trans-Trimethoxyresveratrol is a derivative of Resveratrol(RSV),and it may be a more potent anti-inflammatory,antiangiogenic and vascular-disrupting agent when comparedwith resveratrol. In vitro: The in vitro study of resveratroland trans-Trimethoxyresveratrol showed rather weak cytotoxic…

Bioactivity: Trolox is a vitamin E analogue and is a powerful antioxidant.

Bioactivity: UPF-648 is a potent kynurenine 3-monooxygenase (KMO)inhibitor; exhibits highly active at 1 uM (81 ± 10% KMOinhibition); ineffective at blocking KAT activity. IC50 value:1 uM(81 ± 10 % inhibition) [1] Target: KMO inhibitor in vitro:BFF 122 inhibited KAT activity almost completely at both 1 and…

Bioactivity: Uric acid is an endogenous antioxidant that scavenges reactiveoxygen species (ROS) including singlet oxygen, oxygenradicals, and peroxynitrite.

12 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Sinapinic acid (Sinapic acid) Cat. No.: HY-W009732

Sodium formononetin-3'-sulfonate (Sul-F) Cat. No.: HY-13063

Squalene (Super Squalene; trans-Squalene; AddaVax) Cat. No.: HY-N1214

Succinobucol (AGI-1067; Probucol monosuccinate) Cat. No.: HY-14937

Sulcotrione  Cat. No.: HY-107368

Tetrahydroxyquinone (Tetrahydroxy-1,4-benzoquinone; Tetrahydroxybenzoquinone) Cat. No.: HY-B1106

trans-Trimethoxyresveratrol (trans-trismethoxy Resveratrol;

E-Resveratrol Trimethyl Ether; Tri-O-methylresveratrol) Cat. No.: HY-N1408

Trolox  Cat. No.: HY-101445

UPF-648  Cat. No.: HY-15600

Uric acid  Cat. No.: HY-B2130

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Purity: 97.91%Clinical Data: LaunchedSize: 5 mg, 10 mg, 50 mg, 100 mg

Purity: 99.15%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

10 mg, 50 mg, 100 mg

Purity: 98.0%Clinical Data: Phase 2Size: 10mM x 1mL in DMSO,

5 mg, 10 mg, 25 mg, 50 mg, 100 mg

Purity: 99.99%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

100 mg

Purity: 98.06%Clinical Data: No Development ReportedSize: 10mM x 1mL in DMSO,

5 mg, 10 mg, 25 mg, 50 mg, 100 mg

 

Bioactivity: Urolithin A is an intestinal metabolite of ellagic acid withantioxidant and antiproliferative effects; inhibits T24 andCaco-2 cell growth with values of 43.9 and 49 μM,IC50respectively.

Bioactivity: Veratric acid (3,4-Dimethoxybenzoic acid) is an orally activephenolic compound derived from vegetables and fruits, hasantioxidant and anti-inflammatory activities .[1] [3]

Veratric acid also acts as a protective agent agai…

Bioactivity: Visomitin is a new antioxidant with the highest mitochondrionmembrane penetrating ability and potent antioxidantcapability.

Bioactivity: Xanthotoxol is a biologically active linear furocoumarin,shows strong pharmacological activities as anti-inflammatory,antioxidant, antagonistic, and neuroprotective effects.5-HT

Bioactivity: Zofenopril Calcium (SQ26991) is an antioxidant that acts as anangiotensin-converting enzyme inhibitor. Target: ACEZofenopril Calcium is a pro-drug designed to undergo metabolichydrolysis yielding the active free sulfhydryl compoundzofenoprilat, which is an angiotensin converting enzyme (ACE)…

Urolithin A  Cat. No.: HY-100599

Veratric acid (3,4-Dimethoxybenzoic acid) Cat. No.: HY-N2007

Visomitin (SKQ1) Cat. No.: HY-100474

Xanthotoxol (8-Hydroxypsoralen) Cat. No.: HY-30152

Zofenopril calcium (SQ26991) Cat. No.: HY-B0655