R&D and innovation for health

In Korean hospitals2019. 8. 13.

Professor Kyungsik, Yoon Kyung Hee Univ. Medical CollegeDept. Biochemistry & Mol. Biology

Contents part 1. KOREA

ⅠIOverview of Healthcare in Korea & Globalization of Korean Hospitals

The life expectancy at birth in Korea is

Total Tertiary Hospital

General Hospital Hospital Clinic

Dental Hospital &

Clinic

Traditional Korean

MedicinePharmacy

Local Health

Center, Etc.

92,638 42 301 2,970 31,366 17,712 14,429 22,384 3,434

Ø Patients can freely choose any types of medical institutionsexcept tertiary referral hospitals.

Ø Universal coverage is provided for all the Korean citizens.

Ø Not all medical services are covered by NHI.

History of National Health Insurance (NHI) in Korea

41 medical schools in Korea§ Every year more than 3,000 students graduate from medical schools

§ Education Program and Curriculum- A total year of medical school in Korea is 6 years including 2 years premedical courses and 4 years medical courses

§ Professional training after graduation1 year of

internship program

4 years of residency program

2 years of fellowship

- Doctors complete the residency program⇒ They must pass the Korean Medical Specialist License

Examinationto be certified as a specialist.

- 78,282 specialists (80% of the total 97,713 doctors)

No Specialty No Specialty

1 Internal Medicine 14 Radiology

2 Surgery 15 Radiation Oncology

3 Pediatrics 16 Anesthesiology and Pain Medicine

4 Obstetrics & Gynecology 17 Neurology

5 Psychiatry 18 Rehabilitation Medicine

6 Orthopedic Surgery 19 Tuberculosis Medicine

7 Neurosurgery 20 Clinical Pathology

8 Thoracic and Cardiovascular Surgery 21 Pathology

9 Plastic surgery 22 Preventive Medicine

10 Ophthalmology 23 Family Medicine

11 Otorhinolaryngology 24 Occupational medicine

12 Dermatology 25 Nuclear Medicine

13 Urology 26 Emergency Medicine

ⅠII Direction of Bio-medical R&D in Korea

• 2019 Total Budget: about 20 billion $

• Recently focused to biomedical health research

• R&D of Ministry of Health and welfare

• 43% Skills to overcome disease in diverse clinic area

• 27% New drug & medical divice

• 12% Advancing technology research(regenerative medicine, Precision medicine)

• 10% Infrastructue investment

Response to social environment change

Health care disaster response

Vaccine sovereignty

Reduce medical expense

Expansion of public R & D investment to solve high-cost social problems

Study on overcoming disease for the people

Improvement of feeling through ICT fusion

Strengthen investment in vulnerable groups

Genome, Precision Medicine

Stem cell • regenerative medicine

Smart Hospital

New Drug development

Medical Device

Dental & Oriental Medicine

Dermatology Part

§ Development of surgical instruments, rehabilitation therapy, care-assist robot

Accelerated Application

Standardization

Master model

right Target

Equal Access & Quality

KOREA’s –

Recognition

In 2014, coach Hiddink was treated with 'Cartistem', a treatment for regenerating

knee cartilage

’2013, A four-year-old Austin who suffered from acute

lymphoblastic leukemia was treated with 'Kymriah'

(ALLO-ASC-DFU) treatment for patients with diabetic foot ulcers.

[Cell Therapy] [Gene Therapy] [Tissue Engineering]

04 Bio-medical industry in the 4th industrial revolution era

Big data dependence high & the area where human beings are directly benefited

Healthcare to benefit most from the 4th

industrial revolution, executives predict (Jan 21, 2016 The Economist)

05 New Technologies in Healthcare (the 4th industrial revolution)

Mobility and ConnectivityEmerging Technologies

3D printing, development of genetic engineering technology, and AI / IoT / Big Data technology convergence

05 Always-on Hospital

AI-based integrated monitoring system automatically monitors patient status

Increased patient freedom in the hospitalImproved treatment and diagnostic accuracy

Always-on Hospital

Improved diagnostic accuracy

Improving quality of medical service

Increased satisfaction

05 Hospital in Body

28

4th industrial revolution

AIBig dataIoT

Robot & hardware

RobotNano & micorsystem

+Vascular surgery

Conservative cancer treatment

Image induction surgery

New concept surgical instrument

In Body Robot(Main Role)

Out Body Equipment(Assistant)

New Technology of Disease Treatment

Quality improvement

Overcoming incurable diseases-Future Hospital

MRI, X-ray

+

05 Hospital Factory

Production base of hospitals concentrated on high-quality human resources-Implementation of customized treatment centered on patient / physician

Needs from Hospitals !Proto-types

Efficacy, SafetyFunctions !Animal Tests

Basic Tech.

BiomaterialsManufacturing tech. and devices

Lab. ScaleProto-type

ClinicalTrials

Approval from Gov.

ProductsPre-ClinicalTests

Translational Research

Approval from Gov.

Sales

Insurance

Industrialization

Hospital

Gov.

Industry

06 Bio-Health Eco –Chain (TRAIN)

ü Translation & Industrialization (TRAIN)

07 Key Technology 1

ü Biodegradable Metals [2013~2017 (5years), PI : Dr. Kim Yoo-Chan]

contents

outcomes

(2)‘Long-term clinical study result ofbiodegradable Mg alloy and multiscaleanalysis of in vivo biodegradation’, PNAS 19(2016) 716-721 (IF=9.674)

(1) 2016 Excellent National R&D 100

(3) Proto-type and spin-off

- Spin-off to Grand Projcet (1 mil. US$ per year, 5 years) with manufacturing co.

- Pre-clinical tests with proto-types- Clinical Trial will be finished by 2019

with Screws and plates for oral surgery

BRI Oral Surgery

Urology

07 Key Technology 2

ü Minimally Invasive Robot Surgical Device for Joints [2013~2018 (6years), PI : Dr. Kim Kye-Ree]

§ Applications of Steering cannula and Wire drive style end-effector to joint surgery

§ Tech. Transfer to Hanyang Digitech.

contents

outcomes

Electrosurgical device

Steering cannula Wire drive device

KIST End Effector

Steerable Electrosurgical device

07 Key Technology 3

ü 3D Virtual Surgery System for Cranial Face [2016~2018 (3years), PI : Dr. Kim Young-Joon]

Korean Standard Ophthalmic Model

• Provide Clinical Data

• Clinical ApplicationsCustom made 3-D System:

• 3D virtual surgical Planning SW,

• After surgery analysis SW

3D virtual surgical Planning SW for Ophthalmic Fracture

2 Tech. TransfersKIST bio venture in 2019

contents

outcomes

Contents part 2

ⅠIII Korean Oriental medicine?

01 Introduction-Korean Medicine Hospital

ü General Direction of Korean-Oriental Hospital Jin Yong Lee

• 1971 : The KOREAN MEDICINE Hospital of Kyung-hee University started with the departments of

Internal Medicine, Gynecology, Pediatrics, Acupuncture and Moxibustion, etc. on October 5, 1971

• 1976 : Succeeded in anesthetizing a subject of Caesarean operation by acupuncture on March 22,

1976

Held the first World Congress of Acupunture on October 29, 1976.

• 1977 : Preliminary medical examination appliances of Oriental Medicine and made the data auto-

recorded on September 16, 1977.

• 1981 : Begin publishing the collection of Oriental Medicine materials in July, 1981.

• 1987 : Medical insurance by the government to oriental medicine, treatments in our facilities

began to be covered by medical insurance.

• 2007~Now : We have the 300 beds, 8 special departments, a subsidiary administrative office,

preliminary medical office, medicine office, a team of nurses, etc. preliminary medical office,

medicine office, a team of nurses etc

• In all, we boast more than 300 employees, and treat more than 300,000 outpatients and 120,000

inpatients per year.

02 Introduction-Korean Medicine Hospital

03 Korean Medicine Education System

§ Modern educational System from 1948

§ 11 KM Univ.

- premedical (2) and medical course(4)

§ 1 Graduate School of Pusan National

Univ. (4+4 course)

§ Master and Doctor Degree

§ Annually 800~900 new KMD doctorswho pass the national examination

EDUCATIO

N

EDUCATIO

N

Dong Eui Univ. www.deu.ac.kr

Dong Guk Univ. www.dongguk.ac.kr

Daegu Hanny Univ. www.dhu.ac.kr

Dae Jeon Univ. www.dju.ac.kr

Dong Shin Univ. www.dsu.ac.kr

Ga Chon Univ. www.gachon.ac.krKyung Hee Univ. www.khu.ac.krPusan National Univ. kmed.pusan.ac.kr

Sang Ji Univ. www.sangji.ac.kr

Se Myung Univ. www.semyung.ac.kr

Woo Suk Univ. www.woosuk.ac.kr

Won Kwang Univ. www.wku.ac.kr

List of KM Univ.

§ 19,116 Licensers(‘12) & 17,353 Practitioners(‘12)§ 201 KM Hospitals(over 80 beds) & 12,705 KM Clinics(‘12)

§ Use of Modern Medical Instrument computerized

instruments for diagnosis

§ Cooperative Diagnosis & Treatment with Western Medicine

§ Specialization : Obesity, Sterility, ENT, Aesthetic treatment and Chuna etc

Current Trend

of Clinics

& H

osp

itals

<The Change in the Number of KM Medical Institutions(1995-2012)>

04 Korean Medicine Practice

ⅠIVKyung Hee University Medical Center

& Kyung Hee University

01 Introduction of Kyung Hee Univ. Medical center

KYUNG HEE UNIVERSITY HEALTHCARE SYSTEM was opened in October 5th 1971, as complex of Medical, Dental and Korean healthcare system. Also a top-notch medical facilities consisting of Gangdong Kyung Hee University Hospital(opened June 12th, 2006)

02 World-class R&D platforms Concentrated in the Capital Atea

03 Bio-Competitiveness of Northeast Seoul (Hongneung)

Global Healthcare, outstanding medical center in KoreaThe first university hospital with medical and oriental comprehensive healthcare

Kyung Hee UniversityMedical Center

SEOUL, KOREA

04 KH University Hospital Facility

Land area(㎡) Building area(㎡) BED

Kyung Hee University Medical Center 27,253 110,879 1,047

05 Education in Figures

06 KHU Globalization

ü International Cooperation in Figures

07 Four Seasons (Seoul Campus)

07 Four Seasons (Global Campus)

Thank you.