Quo-Test®A1CIT’S NEVER BEEN SO EASY

Quo-Test®A1CQuotient Diagnostics is proud to introduce Quo-Test A1C, the first assay to be released on the Quo-Test assay platform– a fast one step assay system for Glycated Hemoglobin (A1C). Other important Point of Care parameters will bereleased in the near future, expanding the capabilities of the Quo-Test platform.

Quo-Test A1C exploits the well known affinity of boronic acid to bind to cis-diol groups that are present on carbohy-drates. Quo-Test A1C is a homogeneous assay that requires no separation steps. In practical terms this approach con-fers advantages for the user in ease of operation, speed and system reliability. In performance terms it almost eliminateserrors introduced through operator variability.

Precision Profile

Quo-Test vs Primus

Quo-Test vs Primus

43.5

32.5

21.5

10.5

0

2

1.5

1

0.5

0

-0.5

-1

-1.5

-2

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00 2 4 6 8 10 12 14

CV

(%)

%A

1CQ

uo-T

est

%A

1CQ

uo-T

est

(%)A1c (mean)

% A1C Primus

% A1C Primus

Total

95% CI

y = 0.980x + 0.142R_= 0.978r = 0.989

0 2 4 6 8 10 12 14

Precision & AccuracyQuo-Test A1C delivers excellent accuracy and precision andis ideal for the low-volume laboratory or physician’s office.Quo-Test consistently delivers results which meet therequirements of today’s busy clinics where rapid feedbackof results improves patient outcomes. Quo-Test A1C istraceable to the IFCC reference method and reports resultsin either DCCT, IFCC, mono-S or JDS aligned values.Quo-test A1C has been certified to the NGSP. The calibra-tion data for each lot of reagents is entered into the readervia a barcode supplied with each reagent kit. This onlyneeds to be done once for each lot.

Precision Profile

Quo-Test vs Primus

Quo-Test vs Primus

43.5

32.5

21.5

10.5

0

2

1.5

1

0.5

0

-0.5

-1

-1.5

-2

14

12

10

8

6

4

2

00 2 4 6 8 10 12 14

CV

(%)

%A

1CQ

uo-T

est

%A

1CQ

uo-T

est

(%)A1c (mean)

% A1C Primus

% A1C Primus

Total

95% CI

y = 0.980x + 0.142R_= 0.978r = 0.989

0 2 4 6 8 10 12 14

Bland Altman plot

Correlation

Sample Normal Abnormal

Mean 5.3%A1C 9.9%A1C

Within Run repeatability %CV (n=20)

Between day imprecision %CV 20 days n=4

Total imprecision %CV 20 days (n=4)

2.6% 1.9%

1.4% 0.9%

2.8% 2.5%

Efficient Patient Data Handling and QCSimplicity of use is backed up by a versatile system for handling patient data and providing the necessary connectivity to datamanagement systems. All results are stored within the instrument memory and can be accessed from the key pad. A smalloptional label printer can be attached if required to print results for record keeping. Patient and operator IDs may be storedwith the results using a hand-held barcode reader supplied as standard.

The barcode reader is also used to good effect for the initiation of QC control runs simply by scanning the barcode of theQuo-Test control samples. Control results are tagged with the control lot ID and the pass/fail results of the control.

A USB port enables upload of all results to a PC or LIS.

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Minimal Handling...MinimumHands on TimeNothing can be simpler than the Quo-Test A1C system

• Collect blood sample from a finger prick• Insert sample collector into cartridge• Place cartridge inside analyzer and close the door

The analyzer will automatically identify the cartridge, start the test and deliver the result within 4 minutes.

Incomparably Easy and ReliableUsing patented homogeneous technology Quo-Test A1C exploits the phenome-non of fluorescent quenching where the fluorescence of a boronic acid conjugate isreduced when bound to glycated hemoglobin. The Quo-Test analyzer automatesthe test process combining simultaneous measurements of absorbance and fluores-cence in one sample. The process simplicityof a homogeneous test enables a simple andreliable system. When coupled with analyzersoftware and a simple user interface,designed to detect potential error condi-tions, it delivers incomparable ease of use.

A small footprint and very low weightmeans that the system is at home on adesktop and can easily be transported when necessary.

Quo-Test Analyzer

Russell HouseMolesey RoadWalton on Thames, Surrey, KT12 3PEUnited Kingdomtel +44(0)1932 220124fax +44(0)1932 250266www.quotientdiagnostics.co.ukwww.quo-test.com ISO 13485: 2003 Accredited

Size 205mm(h) x 205mm(w) x 135mm(d)

Weight 1.3kg

Display Blue LCD backlit monochrome display 128x64 pixelsVisible area 70x39mm

Connections USB 2.0 (slave), Printer(serial), Barcode Scanner(PS2)

Data Memory capacity 7000 data records

Mains adapter Separate AC to DC mains adapter

Input 100-240 VAC, 50-60 Hz, 30 W

Output 24 VDC, 1.25A

Analyzer

Method Boronate Affinity Fluorescence Quenching

Range 4-17%

Sample Volume ~4µl finger prick

Time to results 4 mins

Imprecision <3%

Hemoglobin Variants Unaffected by Hb AS, Hb AC, Hb AD, Hb AE, Hb AJ,Hb SS, Hb CC, Hb SC, Hb EE, B-thalassemia and elevated foetal hemoglobin (up to 30%)

Quo-Test A1C Test

Power Supply

Ordering informationCatalogue No Description

0108-0000 Quo-Test Analyzer system

0031 Quo-Test A1C Reagent Kit (15 tests)

0038 Quo-Test A1C Control Kit

0108-0002 Quo-Test Printer

0108-0006 Quo-Test printer labels

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