QS. An Nahl, 16:68

• Dan Tuhanmu mewahyukan kepada lebah: "Buatlah sarang-sarang di bukit-bukit, di pohon-pohon kayu, dan di tempat-tempat yang dibikin manusia",

QS. An Nahl, 16:69

• kemudian makanlah dari tiap-tiap (macam) buah-buahan dan tempuhlah jalan Tuhanmu yang telah dimudahkan (bagimu). Dari perut lebah itu keluar minuman (madu) yang bermacam-macam warnanya, di dalamnya terdapat obat yang menyembuhkan bagi manusia. Sesungguhnya pada yang demikian itu benar-benar terdapat tanda (kebesaran Tuhan) bagi orang-orang yang memikirkan.

• Betina Jantan Betina

…(madu) yang bermacam-macam warnanya…

…(madu) yang bermacam-macam warnanya…

Awet Ribuan Tahun

Ribuan Tahun Masih Layak Konsumsi

Super-Food: Nirkadaluarsa & Obat Mujarab

2. Hidrogen Peroksida

1. Kadar

Gula

6. Mikroba

Probiotik

5. Zat

Fenolik

4. Peptida Antikuman

3. Tingkat Keasaman

1. Kadar Gula: ±70-80%

1. Kadar Gula: ±70-80%

1. Kadar Gula: ±70-80%

+ 22 Gula lebih kompleks lainnya

TABLE 2.-Carbohydrate composition of honey types

Number of samples

Floral type

Dextrose Levulose Sucrose Maltose Higher Sugars

Percent Percent Percent Percent Percent 23 Alfalfa 33.40 39.11 2.64 6.01 .89 25 Alfalfa-sweetclover 33.57 39.29 2.00 6.30 .91 5 Aster 31.33 37.55 .81 8.45 1.04 3 Basswood 31.59 37.88 1.20 6.86 1.44 3 Blackberry 25.94 37.64 1.27 11.33 2.50 5 Buckwheat 29.46 35.30 .78 7.63 2.27 4 Buckwheat, wild 30.50 39.72 .79 7.21 .83 26 “Clover“ 32.22 37.84 1.44 6.60 1.39 3 Clover, alsike 30.72 39.18 1.40 7.46 1.55 3 Clover, crimson 30.87 38.21 .91 8.59 1.63 3 Clover, Hubam 33.42 38.69 .86 6.23 .74 10 Cotton 36.74 39.28 1.14 4.87 .50 3 Fireweed 30.72 39.81 1.28 7.12 2.06 6 Gallberry 30.15 39.85 .72 7.71 1.22 3 Goldenrod 33.15 39.57 .51 6.57 .59 2 Heartsease 32.98 37.23 1.95 5.71 .53 2 Holly 25.65 38.98 1.00 10.07 2.16 3 Honeydew, cedar 25.92 25.16 .68 6.20 9.61 5 Honeydew, oak 27.43 34.84 .84 10.45 2.16 2 Horsemint 33.63 37.37 1.01 5.53 .73 3 Locust, black 28.00 40.66 1.01 8.42 1.90 3 Loosestrife, purple 29.90 37.75 .62 8.13 2.35 3 Mesquite 36.90 40.41 .95 5.42 .35

1. Kadar Gula

Larutan Gula 70-80% Osmosis

Dehidrasi

Super-Food: Nirkadaluarsa & Obat Mujarab

2. Hidrogen Peroksida

1. Kadar

Gula

6. Mikroba

Probiotik

5. Zat

Polifenolik

4. Peptida Antikuman

3. Tingkat Keasaman

Hidrogen Peroksida (H2O2)

Hidrogen Peroksida (H2O2)

Glukosa (dari nektar)

Sukrosa (dari nektar)

Invertase (dalam perut lebah) Glukosa

Asam glukonat + Hidrogen peroksida Glukosa oksidase

(dalam perut lebah)

Glu

kosa

oks

idas

e

(dal

am p

eru

t le

bah

) Fruktosa +

H2O + O2

H2O + O2

Hidrogen Peroksida (H2O2)

Hidrogen peroksida/ Dihidrogen dioksida

(H2O2)

Air/ Didrogen oksida

(H2O)

+ energi panas

Hidrogen Peroksida (H2O2)

Pembersih kuman Obat kumur

Hidrogen peroksida/ Dihidrogen dioksida

(H2O2)

Pemutih industri kertas, detergent, Pemutih gigi, rambut

Bahan bakar roket

Super-Food: Nirkadaluarsa & Obat Mujarab

2. Hidrogen Peroksida

1. Kadar

Gula

6. Mikroba

Probiotik

5. Zat

Polifenolik

4. Peptida Antikuman

3. Tingkat Keasaman

3. Tingkat Keasaman

• pH madu = 3 – 4,5

• Sekitar 18 jenis asam:

• asam format, asam asetat, asam butirat, asam laktat, asam oksalat, asam suksinat, asam tartarat, asam malat, asam piruvat, asam piroglutamat, asam a-ketoglutarat, asam glukollat, asam sitrat, asam maleat, asam 2- atau 3-fosfogliserat, asam a- atau B-gliserofosfat, dan glukosa fosfat.

Super-Food: Nirkadaluarsa & Obat Mujarab

2. Hidrogen Peroksida

1. Kadar

Gula

6. Mikroba

Probiotik

5. Zat

Polifenolik

4. Peptida Antikuman

3. Tingkat Keasaman

4. Peptida Antikuman: “Bee Defensin”

4. Peptida Antikuman: “Bee Defensin”

• Figure 2. Electron micrographs of negatively stained Bacillus subtilis either untreated (A) or treated by lucifensin (Lucilia sericata’s defensin) for 60 min (B). Scale bars represent 1 µm.

Super-Food: Nirkadaluarsa & Obat Mujarab

2. Hidrogen Peroksida

1. Kadar

Gula

6. Mikroba

Probiotik

5. Zat

Polifenolik

4. Peptida Antikuman

3. Tingkat Keasaman

6. Mikroba Probiotik

5. Zat Polifenolik

• could serve as a good source of natural antioxidants effective in reducing the risk of the occurrence of

– heart disease,

– cancer,

– cataracts,

– different inflammatory processes and

– immuno-system decline.

Super-Food: Nirkadaluarsa & Obat Mujarab

2. Hidrogen Peroksida

1. Kadar

Gula

6. Mikroba

Probiotik

5. Zat

Polifenolik

4. Peptida Antikuman

3. Tingkat Keasaman

6. Mikroba Probiotik

• Alejandra Vasquez, a researcher at Lund University:

• In wild and fresh honey, which honey hunters collect from bees’ nests in high cliffs and trees, there are billions of healthy lactic acid bacteria of 13 different types. This is in comparison with the 1-3 different types found in commercial probiotic products, she explains.

• The honey bees have used these bacteria for 80 million years to produce and protect their honey and their bee bread (bee pollen), which they produce to feed the entire bee colony. The researchers have now also shown that the healthy lactic acid bacteria combat the two most serious bacterial diseases to affect honey bees.

http://www.lunduniversity.lu.se/o.o.i.s?news_item=5820&id=24890

Figure 2. In vitro visualization of lactobacilli.

• In vitro visualization of lactobacilli attached to the wall of a honeybee crop using SEM.A, B and C show different areas of a honey crop at similar magnification with visible attachment structures resembling extracellular polymeric substances (EPS). D shows a larger part of the crop with attached bacteria. Photographer Lennart Nilsson.

• doi:10.1371/journal.pone.0033188.g002

Vásquez A, Forsgren E, Fries I, Paxton RJ, et al. (2012) Symbionts as Major Modulators of Insect Health: Lactic Acid Bacteria and Honeybees. PLoS ONE 7(3): e33188. doi:10.1371/journal.pone.0033188

Figure 3. In vivo visualization of LAB biofilm. The red fluorescence shows live-stained bacteria in a LAB biofilm attached to a honey crop. The green fluorescence

shows the nuclei of the honeybee crop cells. The visualized tissue shows a projection of 112 confocal z-sections (through a 37.6 µm z-depth, covering a xy-area of 246×246 µm).

Vásquez A, Forsgren E, Fries I, Paxton RJ, et al. (2012) Symbionts as Major Modulators of Insect Health: Lactic Acid Bacteria and Honeybees. PLoS ONE 7(3): e33188. doi:10.1371/journal.pone.0033188 http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033188

Figure 4. LAB rescue of honeybee larvae from European Foulbrood. Proportion dead larvae in both replicates (total number dead after 21 days). Data presented as a mean for the

three groups fed M. plutonius (107, 106 and105 bacteria ml−1), and the 3 groups fed M. plutonius and LAB. Irrespective of infectious dose, the overall effect from the LAB supplement was a significantly reduced mortality in

the treated groups. Mortality in the uninfected control groups was <7%.

Vásquez A, Forsgren E, Fries I, Paxton RJ, et al. (2012) Symbionts as Major Modulators of Insect Health: Lactic Acid Bacteria and Honeybees. PLoS ONE 7(3): e33188. doi:10.1371/journal.pone.0033188 http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033188

…di dalamnya terdapat obat yang

menyembuhkan bagi manusia…

• Neonatal IV infiltrate treated with medical grade honey

• Traumatic leg wound in teen – treated with medical honey, wound vac and collagen.

Before and after shot of topical honey treatment for 3 weeks. You're welcome. Adapted from Efem (1988)

• Workers package Medihoney wound and burn dressing at the Derma Sciences manufacturing facility in Toronto.

Kelebihan Lain Madu Sebagai Obat Luka

• Tidak perih

• Tidak menjadikan perban merekat pada luka

• Tidak bersifat racun pada sel mamalia

• Melawan beragam jenis mikroba penyakit

• Tidak memicu kekebalan mikroba penyakit

Sekian