INTRODUCTION

WHAT IS PYRETHRUM?

PROPERTIES

Ecofriendly Quick action Low toxicity Multipurpose √ Repellant √ Flushing agent No development of insect immunity

MECHANISM OF ACTION

METHOD OF APPLICATION

Space spray Kills adult mosquitoes & other insects 0.5 – 1 oz of solution/1000 cu ft of

space After spraying windows & doors

should be closed for not less than 30 mins

SYNERGESTIC EFFECT??

Pyrethrum + DDT or Piperonyl (low toxicity) butoxide

Common formulation of PYRETHRIN (Enhanced toxicity)

SYNTHETIC PYRETHROIDS

Replace the natural pyrethrins 10 times more effective Examples:

1) Lambda cyhalothrin(cyano group)

2) Permethrin3) Tetramethrin4) Rosethrin

5) Proparthin

MECHANISM OF ACTION

Affect CNS Prolong deactivation of

voltage gated Na channel

Prolonged excitation of fibres Lambda cyhalothrin-more neurotoxic

-more selectivity

SIDE EFFECTS

PYRETHROIDS Inhalation- coughing,wheezing,shortness

of breath Skin- itching,rash,paraesthesia(lamda

cyhalothrin) Neurotoxic effect-tremor, incoordination,

increased body temp Long term effects-disrupt endocrine

system -carcinogen(thyroid gland)

PIPERONYL BUTOXIDE

Skin ulceration

Eye irritation

Long term-carcinogen

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