· publications on the use of microgrid (1999 – dec 2018) 2018. screening phage-display antibody...

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PUBLICATIONS ON THE USE OF MICROGRID (1999 – DEC 2018) 2018. Screening Phage-Display Antibody Libraries Using Protein Arrays. Ricardo Jara-Acevedo, Paula Díez, María González-González, Rosa María Dégano, Nieves Ibarrola, Rafael Góngora, Alberto Orfao, and Manuel Fuentes. Methods Molecular Biology, January 2018; 1701 (Phage Display): 365-380. (MGII) A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer. Ulrika Wendel, Nina Persson, Christian Risinger, Eva Bengtsson, Björn Nodin, Lena Danielsson, Charlotte Welinder, Gunilla Nordin Fredrikson, Bo Jansson, and Ola Blixt. PLoS One, 8 February 2018; 13(2): e0191872, 22 pp. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805250/pdf/pone.0191872.pdf Calcium Imaging of GPCR Activation Using Arrays of Reverse Transfected HEK293 Cells in a Microfluidic System. Margriet Roelse, Maurice GL Henquet, Harrie A. Verhoeven, Norbert CA de Ruijter, Ron Wehrens, Marco S. van Lenthe, Renger F. Witkamp, Robert D. Hall, and Maarten A. Jongsma. Sensors, 16 February 2018; 18(2): E602, 17 pp. (MGII) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855233/pdf/sensors-18-00602.pdf Improved spot morphology for printed glycan arrays. Maksim Navakouski, Nadezhda Shilova, Nailya Khasbiullina, Alexey Feofanov, Elena Pudova, Kowa Chen, Ola Blixt, and Nicolai Bovin BioTechniques, 1 March 2018; 64(3): 110-116. (MGII) https://www.future-science.com/doi/full/10.2144/btn-2017-0111 Polypeptide and immune modulation. Inventors: Denise Kelly, Angela Patterson, Edouard Monnais, and Imke Mulder. U.S. Patent Application: 2018/0072778 A1, Publication Date: 15 March 2018; (MGII TAS) http://www.freepatentsonline.com/y2018/0072778.html Park, HyoungJun, HyeMi Kim, and Junsang Doh. Multifunctional Microwell Arrays for Single Cell Level Functional Analysis of Lymphocytes. Bioconjugate Chemistry, 21 March 2018; 29(3): 672-679. Composition of Roseburia hominis. Inventors: Denise Kelly, and Imke Mulder. United States Patent: US 9937211 B2, Publication Date: 10 April 2018; (MGII TAS)

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  • PUBLICATIONS ON THE USE OF MICROGRID (1999 – DEC 2018) 2018. Screening Phage-Display Antibody Libraries Using Protein Arrays. Ricardo Jara-Acevedo, Paula Díez, María González-González, Rosa María Dégano, Nieves Ibarrola, Rafael Góngora, Alberto Orfao, and Manuel Fuentes. Methods Molecular Biology, January 2018; 1701 (Phage Display): 365-380. (MGII) A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer. Ulrika Wendel, Nina Persson, Christian Risinger, Eva Bengtsson, Björn Nodin, Lena Danielsson, Charlotte Welinder, Gunilla Nordin Fredrikson, Bo Jansson, and Ola Blixt. PLoS One, 8 February 2018; 13(2): e0191872, 22 pp. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805250/pdf/pone.0191872.pdf Calcium Imaging of GPCR Activation Using Arrays of Reverse Transfected HEK293 Cells in a Microfluidic System. Margriet Roelse, Maurice GL Henquet, Harrie A. Verhoeven, Norbert CA de Ruijter, Ron Wehrens, Marco S. van Lenthe, Renger F. Witkamp, Robert D. Hall, and Maarten A. Jongsma. Sensors, 16 February 2018; 18(2): E602, 17 pp. (MGII) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855233/pdf/sensors-18-00602.pdf Improved spot morphology for printed glycan arrays. Maksim Navakouski, Nadezhda Shilova, Nailya Khasbiullina, Alexey Feofanov, Elena Pudova, Kowa Chen, Ola Blixt, and Nicolai Bovin BioTechniques, 1 March 2018; 64(3): 110-116. (MGII) https://www.future-science.com/doi/full/10.2144/btn-2017-0111 Polypeptide and immune modulation. Inventors: Denise Kelly, Angela Patterson, Edouard Monnais, and Imke Mulder. U.S. Patent Application: 2018/0072778 A1, Publication Date: 15 March 2018; (MGII TAS) http://www.freepatentsonline.com/y2018/0072778.html Park, HyoungJun, HyeMi Kim, and Junsang Doh. Multifunctional Microwell Arrays for Single Cell Level Functional Analysis of Lymphocytes. Bioconjugate Chemistry, 21 March 2018; 29(3): 672-679. Composition of Roseburia hominis. Inventors: Denise Kelly, and Imke Mulder. United States Patent: US 9937211 B2, Publication Date: 10 April 2018; (MGII TAS)

  • https://patents.google.com/patent/US9937211B2/en Targeting microRNAs for the treatment of liver cancer. Inventors: C. Frank Bennett, Ayelet Chajut, Christine Esau, Eric Marcusson, and Noga Yerushalmi. U.S. Patent Application: 2018/0127755 A1, Publication Date: 10 May 2018; (MGII) https://patents.google.com/patent/US20180127755A1/en Gene expression signature for classification of tissue of origin of tumor samples. Inventors: Ranit Aharonov, Nitzan Rosenfeld, and Shai Rosenwald. U.S. Patent Application: 2018/0127835 A1, Publication Date: 10 May 2018; (MGII) https://patents.google.com/patent/US20180127835A1/en High-throughput screening of T7 phage display and protein microarrays as a methodological approach for the identification of IgE-reactive components. Pablo San Segundo-Acosta, María Garranzo-Asensio, Carmen Oeo-Santos, Ana Montero-Calle, Joaquín Quiralte, Javier Cuesta-Herranz, Mayte Villalba, and Rodrigo Barderas. Journal of Immunological Methods, May 2018; 456: 44-53. (MGII) Biomarkers and metabolic patterns in the sediments of evolving glacial lakes as a proxy for planetary lake exploration. Víctor Parro, Yolanda Blanco, Fernando Puente-Sánchez, Luis A. Rivas, Mercedes Moreno-Paz, Alex Echeverría, Guillermo Chong-Díaz, Cecilia Demergasso, and Nathalie A. Cabrol. Astrobiology, May 2018; 18(5): 586-606. (MGII TAS) http://www.cab.inta.es/uploads/noticias/adjuntos/20180726121746.pdf Compositions and methods for prognosis of ovarian cancer. Inventors: Moshe Hoshen, Gila Lithwick Yanai, and Ram Eitan. United States Patent: US 9988690 B2, Publication Date: 5 June 2018; (MGII) https://patents.google.com/patent/US9988690B2/en Activated pancreatic stellate cells regulate macrophage polarization and function in tumor microenvironment. Shakhawan Mustafa PhD Theses, 13 June 2018; Ruperto Carola University Heidelberg, Germany, 122 pp. (MGII) http://archiv.ub.uni-heidelberg.de/volltextserver/24791/1/PhD%20thesis%20_Shakhawan%20Mustafa_19.4.2018.pdf A stress-enhanced model for discovery of disease-modifying gene: Ece1-suppresses the toxicity of α-synuclein A30P. Alex Yen-Yu Chen, and Tim Tully. Neurobiology of Disease, June 2018; 114: 153-163. Perovskite Single-Crystal Microarrays for Efficient Photovoltaic Devices. Jiang Wu, Fengjun Ye, Wenqiang Yang, Zhaojian Xu, Deying Luo, Rui Su, Yifei Zhang, Rui Zhu, and Qihuang Gong. Chemistry of Materials, 11 July 2018; 30(14): 4590-4596. Pharmaceutical Composition. Inventors: Joacim Elmen, Phil Kearney, and Sakari Kauppinen. U.S. Patent Application: 2018/0195062 A1, Publication Date: 12 July 2018; (MGII)

  • https://patents.google.com/patent/US20180195062A1/en A protein microarray assay for serological determination of antigen-specific antibody responses following Clostridium difficile infection. Ola H. Negm, Mohamed Hamed, and Tanya M. Monaghan. JoVE (Journal of Visualized Experiments), 15 July 2018; 136: e57399 (MGII) https://www.jove.com/video/57399/a-protein-microarray-assay-for-serological-determination-antigen Epitope-mapping of the glycoprotein from Crimean-Congo hemorrhagic fever virus using a microarray approach. Amanda Fritzen, Christian Risinger, Gulay Korukluoglu, Iva Christova, Arina Corli Hitzeroth, Natalie Viljoen, Felicity Jane Burt, Ali Mirazimi, and Ola Blixt. PLoS Neglected Tropical Diseases, July 2018; 12(7): e0006598, 15 pp. (MGII) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053253/pdf/pntd.0006598.pdf Constraints on the Metabolic Activity of Microorganisms in Atacama Surface Soils Inferred from Refractory Biomarkers: Implications for Martian Habitability and Biomarker Detection. Mary Beth Wilhelm, Alfonso F. Davila, Mary N. Parenteau, Linda L. Jahnke, Mastewal Abate, George Cooper, Erin Taylor Kelly, Victor Parro García, Miriam G. Villadangos, Yolanda Blanco, Brian Glass, James J. Wray, Jennifer L. Eigenbrode, Roger E. Summons, and Kimberly Warren-Rhodes Astrobiology, July 2018; 18(7): 955-966. Modifications of konjac glucomannan for diverse applications. Fan Zhu Food Chemistry, 1 August 2018; 256:419-426. Surface-Bound Gradient Deposition of Protein Nanoparticles for Cell Motility Studies. Witold I. Tatkiewicz, Joaquin Seras-Franzoso, Elena Garcia-Fruitós, Esther Vazquez, Adriana R. Kyvik, Judith Guasch, Antonio Villaverde, Jaume Veciana, and Imma Ratera. ACS Applied Materials & Interfaces, 1 August 2018; 10(30): 25779-25786. Reagents and Methods for miRNA Expression Analysis and Identification of Cancer Biomarkers. Inventors: Paul Gerald Ahlquist, Srikumar Sengupta, Johan Arie Den Boon, Bill Sugden, and Michael Abbott Newton U.S. Patent Application: 2018/0230546 A1, Publication Date: 16 August 2018. (MGII) https://patents.google.com/patent/US20180230546A1/en cDNA Microarray Analysis of Insulin Resistance-associated Genes in Fructose-fed Rats. Bo Wang, Yuming Li, Xuyan Zhao, Shaoxi Cao, and Yanwei Zhang. Agricultural Biotechnology, August 2018; 7(4): 93-99 (MGI) Microbial glycans as a target of human intelectin. Inventors: Laura L. Kiessling, Darryl A. Wesener, and Kittikhun Wangkanont. United States Patent: US 10082506 B2, Publication Date: 25 September 2018; (MGII) https://patents.google.com/patent/US10082506B2/en Bacterium for use as a probiotic for nutritional and medical applications. Inventors: Denise Kelly, and Imke Mulder. U.S. Patent Application: 2018/0271918 A1, Publication Date: 27 September 2018; (MGII) https://patents.google.com/patent/US20180271918A1/en

  • Development and Assessment of a Diagnostic DNA Oligonucleotide Microarray for Detection and Typing of Meningitis-Associated Bacterial Species. Stephanie Bannister, Stephen Kidd, Elizabeth Kirby, Sonal Shah, Anvy Thomas, Richard Vipond, Michael Elmore, Andrew Telfer Brunton, Peter Marsh, Steve Green, Nigel J. Silman, Karen E. Kempsell High-throughput, 16 October 2018, 7(4): 32, 30 pp. (MGII) https://www.mdpi.com/2571-5135/7/4/32 Screening Phage-Display Antibody Libraries Using Protein Arrays. Ricardo Jara-Acevedo, Paula Díez, María González-González, Rosa María Dégano, Nieves Ibarrola, Rafael Góngora, Alberto Orfao, and Manuel Fuentes. Methods Molecular Biology, 2018; 1701(Phage Display): 365-380. (MGII) Neuregulin 1 discovered as a cleavage target for the HCV NS3/4A protease by a microfluidic membrane protein array. Nika Schwartz, Michal Pellach, Yair Glick, Reuven Gil, Gahl Levy, Dorit Avrahami, Efrat Barbiro-Michaely, Yaakov Nahmias, and Doron Gerber. New Biotechnology, 25 October 2018; 45: 113-122 (MG 610) Unintentional Genomic Changes Endow Cupriavidus metallidurans with an Augmented Heavy-Metal Resistance. Felipe Millacura, Paul Janssen, Pieter Monsieurs, Ann Janssen, Ann Provoost, Rob Van Houdt, Luis Rojas. Genes, 13 November 2018; 9(11): 551, 17 pp. https://www.mdpi.com/2073-4425/9/11/551 High-throughput screening of T7 phage display and protein microarrays as a methodological approach for the identification of IgE-reactive components. Pablo San Segundo-Acosta, María Garranzo-Asensio, Carmen Oeo-Santos, Ana Montero-Calle, Joaquín Quiralte, Javier Cuesta-Herranz, Mayte Villalba, Rodrigo Barderas Journal of Immunological Methods, 20 February 2018; ahead of print. (MGII) Detecting Nonvolatile Life-and Nonlife-Derived Organics in a Carbonaceous Chondrite Analogue with a New Multiplex Immunoassay and Its Relevance for Planetary Exploration. Moreno-Paz, Mercedes, Ana Gómez-Cifuentes, Marta Ruiz-Bermejo, Oliver Hofstetter, Angel Maquieira, Juan M. Manchado, Sergi Morais, Sephton Mark A., Niessner Reinhard, Knopp Dietmar, Parro Victor Astrobiology, 11 April 2018; ahead of press. (MGII TAS600) https://www.liebertpub.com/doi/abs/10.1089/ast.2017.1747 Application of lectin microarrays for the analysis of seminal plasma glycome. Justina Kołodziejczyk, O. Blixt, Beata Olejnik, M. Zimmer, and Miroslawa Ferens-Sieczkowska. Andrologia, 17 April 2018; e13018, ahead of print. (MGII) Specific glycosaminoglycan chain length and sulfation patterns are required for cell uptake of tau vs. α-synuclein and β-amyloid aggregates. Barbara E. Stopschinski, Brandon B. Holmes, Gregory M. Miller, Victor A. Manon, Jaime Vaquer-Alicea, William L. Prueitt, Linda C. Hsieh-Wilson, and Marc I. Diamond. Journal of Biological Chemistry, 11 May 2018; jbc-RA117, ahead of print. (MGII) http://www.jbc.org/content/early/2018/05/11/jbc.RA117.000378.long

  • Tunable DNA Hybridization Enables Spatially and Temporally Controlled Surface-Anchoring of Biomolecular Cargo. Roland Hager, Andreas Arnold, Eva Sevcsik, Gerhard J. Schütz, and Stefan Howorka. Langmuir, 30 August 2018; ahead of print. 2017. Compositions and methods for prognosis of ovarian cancer. Inventors: Moshe Hosen, Gila Lithwick Yanai, and Ram Eitan. United States Patent: US 9540695 B2, Publication Date: 10 January 2017; (MGII) https://www.google.com/patents/US9540695 Estrogen Enhances the Expression of the Multidrug Transporter Gene ABCG2 - Increasing Drug Resistance of Breast Cancer Cells through Estrogen Receptors Fung-Wei Chang, Hueng-Chuen Fan, Jui-Ming Liu, Tai-Ping Fan, Jin Jing, Chia-Ling Yang, Ren-Jun Hsu International J. Molecular Sciences, 14 January 2017; 18(1), 163, 15 pp. (MGII 610) http://www.mdpi.com/1422-0067/18/1/163/htm Compositions and methods for treatment of ovarian cancer. Inventor: Noga Yerushalmi U.S. Patent Application: 2017/0015999 A1, Publication Date: 19 January 2017; (MGII) https://patents.google.com/patent/US20170015999A1/en Dysregulation of Systemic and Mucosal Humoral Responses to Microbial and Food Antigens as a Factor Contributing to Microbial Translocation and Chronic Inflammation in HIV-1 Infection. Zdenek Hel, Jun Xu, Warren L. Denning, E. Scott Helton, Richard PH Huijbregts, Sonya L. Heath, E. Turner Overton, Benjamin S. Christmann, Charles O. Elson, Paul A. Goepfert, Jiri Mestecky PLoS Pathogens, 26 January 2017; 13(1): e1006087, 20 pp. (MGII) http://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1006087&type=printable Control and automation of multilayered integrated microfluidic device fabrication. Sarit Kipper, Ludmila Frolov, Ortal Guy, Michal Pellach, Yair Glick, Asaf Malichi, Binyamin A. Knisbacher, Efrat Barbiro-Michaely, Dorit Avrahami, Yehuda Yavets-Chen, Erez Y. Levanon and Doron Gerber Lab on a Chip, 31 January 2017; 17(3): 557-566. (MGII 610) Oxidative stress-induced CREB upregulation promotes DNA damage repair prior to neuronal cell death protection. Nicolás Pregi, Laura María Belluscio, Bruno Gabriel Berardino, Daniela Susana Castillo, and Eduardo Tomás Cánepa. Molecular and Cellular Biochemistry, January 2017; 425(1): 9–24 (MGII) https://www.researchgate.net/profile/Nicolas_Pregi/publication/309734971_Oxidative_stress-induced_CREB_upregulation_promotes_DNA_damage_repair_prior_to_neuronal_cell_death_protection/links/59e8b6e60f7e9bc89b5628f7/Oxidative-stress-induced-CREB-upregulation-promotes-DNA-damage-repair-prior-to-neuronal-cell-death-protection.pdf The application of protein microarray assays in psychoneuroimmunology.

  • K. Ayling, T. Bowden, P. Tighe, Ian Todd, E. M. Dilnot, O. H. Negm, L. Fairclough, Kavita Vedhara. Brain, Behavior, and Immunity, January 2017; 59: 62-66. (MGII 610) http://eprints.nottingham.ac.uk/37067/1/Ayling%20Brain%20Behav%20Immun%202016%20AAM.pdf Experimental Protocol for Detecting Cyanobacteria in Liquid and Solid Samples with an Antibody Microarray Chip. Yolanda Blanco, Mercedes Moreno-Paz, and Victor Parro. JoVE (Journal of Visualized Experiments), 7 February 2017; 120: e54994, (MGII TAS) https://www.jove.com/video/54994/experimental-protocol-for-detecting-cyanobacteria-liquid-solid Control and Automation of Multilayered Integrated Microfluidic Device Fabrication. Sarit Kipper, Ludmila Frolov, Ortal Guy, Michal Pellach, Yair Glick, Asaf Malichi, Binyamin Knisbacher Efrat Barbiro-Michaely, Dorit Avrahami, Yehuda Yavets-Chen, Erez Y. Levanon and Doron Gerber Lab on a Chip, 7 February 2017; 17(3): 557-566 (MGII 610) Comparison of the tumor cell secretome and patient sera for an accurate serum-based diagnosis of pancreatic ductal adenocarcinoma. Shakhawan Mustafa, Longqiang Pan, Aseel Marzoq, Malak Fawaz, Laureen Sander, Felix Rückert, Andrea Schrenk, Christina Hartl, Rico Uhler, Adem Yildirim, Oliver Strobel, Thilo Hackert, Nathalia Giese, Markus W Büchler, Jörg D Hoheisel, and Mohamed Saiel Alhamdani Saeed Oncotarget, 14 February 2017; 8(7): 11963-11976. (MGII) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355318/pdf/oncotarget-08-11963.pdf Label-free immuno-sensors for the fast detection of Listeria in food. Alexandra Morlay, Aurore Duquenoy, Félix Piat, Roberto Calemczuk, Thibaut Mercey, Thierry Livache, and Yoann Roupioz. Measurement, February 2017; (98): 305–310 (MGII 600) Structural analysis and unique molecular recognition properties of a Bauhinia forficata lectin that inhibits cancer cell growth. Jacek Lubkowski, Sarah V. Durbin, Mariana CC Silva, David Farnsworth, Jeffrey C. Gildersleeve, Maria Luiza V. Oliva, and Alexander Wlodawer. The FEBS Journal, February 2017; 284(3): 429-450. (MGII) https://febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.13989 Bilateral photoplethysmography for arterial steal detection in arteriovenous fistula using a fractional-order decision-making quantizer. Jian-Xing Wu, Guan-Chun Chen, Ming-Jui Wu, Chia-Hung Lin, and Tainsong Chen. Medical & Biological Engineering & Computing, February 2017; 55(2): 257-270 Non-invasive bat species identification from mixed-species samples using a microarray. Lorelei E. Patrick, Jan M. Just, and Maarten J. Vonhof. Conservation Genetics Resources, 1 March 2017; 9(1): 139-149. Reaction vessel for carrying out array processes. Inventors: Torsten Schulz, Eugen Ermantraut, Ralf Ehricht, Klaus-Peter Mobius, Gerd Wagner, Joachim Fischer, and Thomas Ellinger. U.S. Patent Application: 2017/0058334 A1, Publication Date: 2 March 2017; (MGII) https://patents.google.com/patent/US20170058334A1/en

  • The role of indoleamine 2, 3-dioxygenase-aryl hydrocarbon receptor pathway in the TLR4-induced tolerogenic phenotype in human DCs. Fabián Salazar, Dennis Awuah, Ola H. Negm, Farouk Shakib, and Amir M. Ghaemmaghami. Scientific Reports, 3 March 2017; 7: 43337, 11 pp. (MG 610) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335671/pdf/srep43337.pdf Compositions and methods for prognosis of ovarian cancer. Inventors: Moshe Hosen, Gila Lithwick Yanai, and Ram Eitan. U.S. Patent Application: 2017/0073775 A1, Publication Date: 16 March 2017; (MGII) https://www.google.com/patents/US20170073775 Protein scaffolds for antibody mimics and other binding proteins Inventors: Dasa Lipovsek, Richard W. Wagner, and Robert G. Kuimelis. United States Patent: US 9605039 B2, Publication Date: 28 March 2017; https://www.google.com/patents/US9605039 Methods of isolating distinct pancreatic cell types. Inventors: Michael Walker, Yoav Soen, and Revital Sharivkin. U.S. Patent Application: 2017/0087190 A1, Publication Date: 30 March 2017; https://www.google.com/patents/US20170087190 Non-invasive bat species identification from mixed-species samples using a microarray. Lorelei E. Patrick, Jan M. Just, and Maarten J. Vonhof. Conservation Genetics Resources, March 2017; 9(1): 139-149. https://www.researchgate.net/profile/Lorelei_Patrick/publication/308340638_Non-invasive_bat_species_identification_from_mixed-species_samples_using_a_microarray/links/57e520d608aea8cc2b2faada.pdf?origin=publication_list The role of novel genes in CNS axon regeneration. Sharif H. Almutiri PhD Theses, March 2017; University of Birmingham, 251 pp. (MGII) http://etheses.bham.ac.uk/7475/3/Almutiri17PhD.pdf Screening and validation of novel biomarkers in osteoarticular pathologies by comprehensive combination of protein array technologies. Álvaro Sierra-Sánchez, Diego Garrido-Martín, Lucía Lourido, María González-González, Paula Díez, Cristina Ruiz-Romero, Ronald Sjöber, Conrad Friedrich Droste, Javier De Las Rivas, Peter Nilsson, Francisco Javier Blanco García, and Manuel Fuentes Journal of Proteome Research, 5 May 2017; 16(5): 1890-1899. (MGII) https://www.arrayjet.co.uk/uploads/tinymce/Salamanca%20-%20Sierra- Sanchez%20et%20al%20(2017)%20-%20Screening%20and%20validation%20of%20novel%20biomarkers.pdf Linear Multiepitope (Glyco) peptides for Type-Specific Serology of Herpes Simplex Virus (HSV) Infections. Christian Risinger, Kasper K. Sørensen, Knud J. Jensen, Sigvard Olofsson, Tomas Bergström, Ola Blixt. ACS Infectious Diseases, 12 May 2017; 3(5): 360-367. Development of a protein microarray platform for the characterization of antibodies and quantitative immunoassays.

  • Janek Norman Kibat PhD Theses, 16 May 2017; Ludwig-Maximilians- Universität München, 125 pp. (MGII 610) https://edoc.ub.uni-muenchen.de/22889/1/Kibat_Janek.pdf Probiotic function of human intelectin. Inventors: Laura L. Kiessling, Darryl A. Wesener, Federico Rey, and Kittikhun Wangkanont. U.S. Patent Application: 2017/0136088 A1, Publication Date: 18 May 2017; (MGII) http://www.freepatentsonline.com/y2017/0136088.html Staphylococcus aureus subtyping and detection of MRSA on a microfluidic lab-on-Foil device. Anna Ohlander, Sergey Zelenin, Flavia Huygens, Christoph Kutter, and Aman Russom. DiVA, 29 May 2017; QC 20170427, (MGII) Proteopathic seeding in neurodegeneration: Cellular mechanisms, diagnostics, and therapeutics. Brandon Blake Holmes PhD Theses, May 2017; Washington University, St. Louis, 180 pp. Protein Microarrays in Neurodegenerative Diseases. Pablo San Segundo-Acosta, María Garranzo-Asensio, Ana Montero-Calle, Carmen Oeo-Santos, Mayte Villalba, Ana Guzman-Aranguez, and Rodrigo Barderas. Neuromethods, 28 June 2017; 127 (Current Proteomic Approaches Applied to Brain Function): 43-62. (online publication) (MGII) Transcriptome-based prediction of hybrid performance with unbalanced data from a maize breeding programme. Carola Zenke-Philippi, Matthias Frisch, Alexander Thiemann, Felix Seifert, Tobias Schrag, Albrecht E. Melchinger, Stefan Scholten, and Eva Herzog. Plant Breeding, June 2017; 136(3): 331-337. (MGII) Peripheral killer cells do not differentiate between asthma patients with or without fixed airway obstruction Carolyn Tubby, Ola H. Negm, Timothy Harrison, Patrick J. Tighe, Ian Todd, and Lucy C. Fairclough. Journal of Asthma, June 2017; 54(5): 456-466 (MG 610) http://eprints.nottingham.ac.uk/39043/1/s1-ln24051904397481984-1939656818Hwf1158199077IdV-50649516624051904PDF_HI0001.pdf Protective antibodies against Clostridium difficile are present in intravenous immunoglobulin and are retained in humans following its administration. O. H. Negm, B. MacKenzie, M. R. Hamed, O. A. J. Ahmad, C. C. Shone, D. P. Humphreys, K. Ravi Acharya, C.E. Loscher, I. Marszalowska, M. Lynch, M. H. Wilcox, and T. M. Monaghan Clinical & Experimental Immunology, June 2017; 188(3): 437-444 (MGII) Epitope mapping of a new anti-Tn antibody detecting gastric cancer cells. Nina Persson, Nicolai Stuhr-Hansen, Christian Risinger, Stefan Mereiter, António Polónia, Karol Polom, András Kovács, Franco Roviello, Celso A Reis, Charlotte Welinder, Lena Danielsson, Bo Jansson, and Ola Blixt Glycobiology, 1 July 2017; 27(7): 635-645. (MGII) https://gge.biomedtrain.eu/Media/Shared/uploaded/Files/9/0/0/5.pdf

  • A signalome screening approach in the autoinflammatory disease TNF Receptor Associated Periodic Syndrome (TRAPS) highlights the anti-inflammatory properties of drugs for repurposing. Ian Todd, Ola H. Negm, Jenna Reps, Paul Radford, Grazziela Figueredo, Elizabeth M. McDermott, Elizabeth Drewe et al. Richard J. Powell, Susan Bainbridge, Mohamed Hamed, SharonCrouch, Jon Garibaldi, Steve St-Gallay, Lucy C. Fairclough, Patrick J. Tighe Pharmacological Research, 30 August 2017; 125(Pt.B): 188-200 (MGII 610). Compositions and methods for prognosis of gastric cancer. Inventors: Moshe Hoshen, and Raruch Brenner. United States Patent: US 9765334 B2, Publication Date: 19 September 2017. (MGII) https://patents.google.com/patent/US9765334B2/en Method of detecting cancer based on glycan biomarkers Inventors: Linda C. Hsieh-Wilson, Wen Yi, and Jean-Luc Chaubard. United States Patent: US 9766245 B2, Publication Date: 19 September 2017 (MGII) https://patents.google.com/patent/US9766245B2/en Human gut symbiont Roseburia hominis promotes and regulates innate immunity. Angela M. Patterson, Imke E. Mulder, Anthony J. Travis, Annaig Lan, Nadine Cerf-Bensussan, Valerie Gaboriau-Routhiau, Karen Garden, Elizabeth Logan, Margaret I. Delday, Alistair G. P. Coutts, Edouard Monnais, Vanessa C. Ferraria, Ryo Inoue, George Grant, and Rustam I. Aminov Frontiers in Immunology, 26 September 2017; 8: 1166, 14 pp. (MGII TAC + GeneTAC) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622956/pdf/fimmu-08-01166.pdf Protein scaffolds for antibody mimics and other binding proteins. Inventors: Dasa Lipovsek, Richard W. Wagner, and Robert G. Kuimelis. U.S. Patent Application: 2017/0275342 A1, Publication Date: 28 September 2017. https://patents.google.com/patent/US20170275342A1/en Biomarkers for human papilloma virus-associated cancers. Inventors: Dohun Pyeon, Paul F. Lambert, Michael A. Newton, and Paul G. Ahlquist. United States Patent: US 9790553 B2, Publication Date: 17 October 2017. (MGII) https://patents.google.com/patent/US9790553B2/en Active Antioxidizing Particles for On-Demand Pressure-Driven Molecular Release. Yongbeom Seo, Jiayu Leong, Jye Yng Teo, Jennifer W. Mitchell, Martha U. Gillette, Bumsoo Han, Jonghwi Lee, and Hyunjoon Kong. ACS Applied Materials & Interfaces, 18 October 2017; 9(41): 35642-35650. Distinct glycosaminoglycan chain length and sulfation patterns required for cellular uptake of Tau, Aβ, and α-Synuclein. Barbara E. Stopschinski, Brandon B. Holmes, Gregory M. Miller, Jaime Vaquer-Alicea, Linda C. Hsieh-Wilson, and Marc I. Diamond. bioRxiv, 21 October 2017; 207035 (MGII) https://www.biorxiv.org/content/biorxiv/early/2017/10/21/207035.full.pdf Polypeptide and immune modulation. Inventors: Denise Kelly, Angela Patterson, Edouard Monnais, and Imke Mulder. United States Patent: US 9796762 B2, Publication Date: 24 October 2017. (MGII TAS) https://patents.google.com/patent/US9796762B2/en

  • MicroRNAs expression signature for determination of tumors origin. Inventors: Nitzan Rosenfeld, Shai Rosenwald, Iris Barshack, and Dvora Nass. United States Patent: US 9803247 B2, Publication Date: 31 October 2017 (MGII) https://patents.google.com/patent/US9803247B2/en Autoantibodies of IgM and IgG classes show differences in recognition of multiple autoantigens in chronic obstructive pulmonary disease. Reham Shindi, Amna Almehairi, Ola H. Negm, Noor Kalsheker, Nichola S. Gale, Dennis J. Shale, Timothy W. Harrison, Charlotte E.Bolton, MichelleJohn, IanTodd, Patrick J.Tighe, Lucy C.Fairclough Clinical Immunology, October 2017; 183: 344-353. (MGII) Protein scaffolds for antibody mimics and other binding proteins. Inventors: Dasa Lipovsek, Richard W. Wagner, and Robert G. Kuimelis. U.S. Patent Application: 2017/0334958 A1, Publication Date: 23 November 2017. http://www.freepatentsonline.com/y2017/0334958.html A signalome screening approach in the autoinflammatory disease TNF Receptor Associated Periodic Syndrome (TRAPS) highlights the anti-inflammatory properties of drugs for repurposing. Ian Todd, Ola H. Negm, Jenna Reps, Paul Radford, Grazziela Figueredo, Elizabeth M. McDermott, Elizabeth Drewe, Richard J. Powell, Susan Bainbridge, Mohamed Hamed, Sharon Crouch, Jon Garibaldi, Steve St-Gallay, Lucy C. Fairclough, Patrick J. Tighe Pharmacological Research, November 2017; 125(part B): 188-200. (MG610) Diagnosis and prognosis of various types of cancers. Inventors: Ranit Aharonov, Nitzan Rosenfeld, and Hila Benjamin. United States Patent: US 9834821 B2, Publication Date: 5 December 2017. (MGII) https://patents.google.com/patent/US9834821B2/en Divergent responses of forest soil microbial communities under elevated CO2 in different depths of upper soil layers. Hao Yu, Zhili He, Aijie Wang, Jianping Xie, Liyou Wu, Joy D. Van Nostrand, Decai Jin, Zhimin Shao, Christopher W. Schadt, Jizhong Zhou, Ye Deng Applied and Environmental Microbiology, 15 December 2017; 84(1): e01694-17, 13 pp. (MGII) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734029/pdf/e01694-17.pdf Targeting microRNAs for the treatment of liver cancer. Inventors: C. Frank Bennett, Ayelet Chajut, Christine Esau, Eric Marcusson, and Noga Yerushalmi. United States Patent: US 9845470 B2, Publication Date: 19 December 2017; (MGII) https://patents.google.com/patent/US9845470B2/en Microarray Technologies in Fungal Diagnostics. Steffen Rupp Methods Molecular Biology, 2017; 1508 (Human Fungal Pathogen Identification): 385-409. (MGII) Discovery of RNA Binding Small Molecules Using Small Molecule Microarrays Colleen M. Connelly, Fardokht A. Abulwerdi, and John S. Schneekloth. Methods Molecular Biology, 2017; 1518 (Small Molecule Microarrays): 157-175. (MGII) Label-free immuno-sensors for the fast detection of Listeria in food.

  • Alexandra Morlay, Aurore Duquenoy, Félix Piat, Roberto Calemczuk, Thibaut Mercey, Thierry Livache, and Yoann Roupioz. Methods Molecular Biology, 2017; 1600 (Microbial Toxins): 49-59 (MGII 600) Multiplex Fluorescent Antibody Microarrays and Antibody Graphs for Microbial and Biomarker Detection in the Environment. Yolanda Blanco, Mercedes Moreno-Paz, Jacobo Aguirre, and Victor Parro. In: Hydrocarbon and Lipid Microbiology Protocols, 2017; Terry J. McGenity, Kenneth N. Timmis, Balbina Nogales Eds, Humana Press, pp. 207-224 (MGII TAS) 2016. Lipid dip-pen nanolithography on self-assembled monolayers. Martynas Gavutis, Vytautas Navikas, Tomas Rakickas, Šarūnas Vaitekonis, and Ramūnas Valiokas. Journal of Micromechanics and Microengineering, 11 January 2016; 26(2): 025016. An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation. Linda Smit, Katrien Berns, Katherine Spence, W. David Ryder, Nik Zeps, Mandy Madiredjo, Roderick Beijersbergen, René Bernards, and Robert B. Clarke. Oncotarget, 19 January 2016; 7(3): 2596-2610. (MGII) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823058/ Peptide microarrays as diagnostic tool for cancer associated protease profiling Eric Dyrcz PhD Theses, 29 January 2016; Ruprecht- Karls -Universität, Heidelberg, 89 pp. (MGII) http://archiv.ub.uni-heidelberg.de/volltextserver/20237/1/Dyrcz_Diss_pdfA.pdf Clinical utility of reverse phase protein array for molecular classification of breast cancer. Ola H. Negm, Abir A. Muftah, Mohammed A. Aleskandarany, Mohamed R. Hamed, Dena AJ Ahmad, Christopher C. Nolan, Maria Diez-Rodriguez, Patrick J. Tighe, Ian O. Ellis, Emad A. Rakha, Andrew R. Green Breast Cancer Research and Treatment, January 2016; 155(1): 25-35. (MG610) Drop impact on a solid surface C. Josserand, and S. T. Thoroddsen. Annual Review of Fluid Mechanics, January 2016; 48: 365-391. The identification and characterization of resistance in Musa to Fusarium oxysporum F.sp cubense race 1. Reuben Tendo Ssali PhD Theses, January 2017; Stellenbosch University, South Africa (MGII) http://www.sun.ac.za/english/faculty/agri/plant-pathology/ac4tr4/Documents/Tendo%20Ssali%20(Maart%202016).pdf A Double-Hybridization Approach for the Transcription-and Amplification-Free Detection of Specific mRNA on a Microarray.

  • Michaela Haider, Thomas Haselgrübler, Alois Sonnleitner, Fritz Aberger, and Jan Hesse. Microarrays, 23 February 2016; 5(1): 5, 10 pp. (MGII) http://www.mdpi.com/2076-3905/5/1/5/htm Diagnosis of multiple sclerosis. Inventors: Howard L. Weiner, Irun R. Cohen, and Francisco J. Quintana. United States Patent: US 9267945 B2, Publication Date: 23 February 2016. https://www.google.com/patents/US9267945 The Effects of Sequence Variation on Genome-wide NRF2 Binding—New Target Genes and Regulatory SNPs. Suvi M. Kuosmanen, Sari Viitala, Tuomo Laitinen, Mikael Peräkylä, Petri Pölönen, Emilia Kansanen, Hanna Leinonen, Suresh Raju, Anke Wienecke-Baldacchino, Ale Närvänen, Antti Poso, Merja Heinäniemi, Sami Heikkinen, and Anna-Liisa Levonen Nucleic Acids Research, 29 February 2016; 44(4): 1760-1775. (MGII) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770247/ Identification of novel biomarkers in chronic immune thrombocytopenia (ITP) by microarray-based serum protein profiling. Gürkan Bal, Matthias E. Futschik, Daniela Hartl, Frauke Ringel, Julian Kamhieh-Milz, Viktor Sterzer, Jörg D. Hoheisel, Mohamed SS Alhamdani, and Abdulgabar Salama. British Journal of Haematology, February 2016; 172(4): 602-615. AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects. Diána Papp, Tibor Kovács, Viktor Billes, Máté Varga, Anna Tarnóci, László Hackler Jr, László G. Puskás, Hanna Liliom, Krisztian Tarnok, Katalin Schlett, Adrienn Borsy, Zsolt Padar, Attila L Kovacs, Krisztina Hegedus, Gabor Juhasz, Marcell Komlos, Attila Erdos, Balazs Gulyas, and Tibor Vellai Autophagy, February 2016; 12(2): 273-286. (MG II) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835959/pdf/kaup-12-02-1082023.pdf Pharmaceutical composition for inhibition of disease-inducing microRNAs. Inventors: Joacim Elmen, Phil Kearney, and Sakari Kauppinen. U.S. Patent Application: 2016/0060627 A1, Publication Date: 3 March 2016. (MGII) http://www.freepatentsonline.com/y2016/0060627.html Diagnosis of autoimmune diseases using a specific antibody profile. Inventors: Irun R. Cohen, Eytan Domany, Ittai Fattal, and Noam Shental. U.S. Patent Application: 2016/0069896 A1, Publication Date: 10 March 2016; (MG600) http://www.freepatentsonline.com/y2016/0069896.html Methods of identifying glycopeptides recognized by disease-associated auto-antibodies. Inventor: Edward Nudelman U.S. Patent Application: 2016/0084844 A1, Publication Date: 24 March 2016. http://www.freepatentsonline.com/y2016/0084844.html BerEP4 and AE1/3 are Reliable Markers of Epithelial Content for Biomarker Discovery Using Reverse Phase Protein Arrays (RPPA). Ola H Negm, James C Hassall, Wakkas Fadhil, Alain Pitiot, Patrick J Tighe, Cedric Marchessoux and Mohammad Ilyas

  • Int J. Pathology Clinical Research, 31 March 2016; 2(2): 031, 7 pp. (MGII 610) https://www.researchgate.net/profile/Ola_Negm2/publication/305033168_BerEP4_and_AE13_are_Reliable_Markers_of_Epithelial_Content_for_Biomarker_Discovery_Using_Reverse_Phase_Protein_Arrays_RPPA/links/577f7ca508ae5f367d36dc31.pdf DTW-MIC coexpression networks from time-course data. Samantha Riccadonna, Giuseppe Jurman, Roberto Visintainer, Michele Filosi, and Cesare Furlanello. PLoS One, 31 March 2016; 11(3): e0152648, 29 pp. (MGII) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816347/pdf/pone.0152648.pdf Data in support of proteomic analysis of pneumococcal pediatric clinical isolates to construct a protein array. Alfonso Olaya-Abril, Ignacio Obando, and Manuel J. Rodríguez-Ortega. Data in Brief, March 2016; 6: 917-922 (MGII 610) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758182/ Somaclonal variants of taro (Colocasia esculenta Schott) and yam (Dioscorea alata L.) are incorporated into farmers’ varietal portfolios in Vanuatu. H. Vandenbroucke, P. Mournet, H. Vignes, R. Malapa, M. F. Duval, and V. Lebot. Genetic Resources and Crop Evolution, March 2016; 63(3): 495-511 (MGII) High-throughput microarray mapping of cell wall polymers in roots and tubers during the viscosity-reducing process. Yuhong Huang, William G. Willats, Lene Lange, Yanling Jin, Yang Fang, Armando A. Salmeán, Henriette L. Pedersen, Peter Kamp Busk, and Hai Zhao. Biotechnology and Applied Biochemistry, March 2016; 63(2): 178-189. (MGII) Microarrays–new possibilities for detecting biological factors hazardous for humans and animals, and for use in environmental protection. Tomasz Mirski, Michał Bartoszcze, Agata Bielawska-Drózd, Romuald Gryko, Janusz Kocik, Marcin Niemcewicz, and Krzysztof Chomiczewski. Annals of Agricultural and Environmental Medicine: AAEM, March 2016; 23(1): 30-36. (MGII) https://www.researchgate.net/profile/Michal_Bartoszcze3/publication/299395877_Microarrays_-_new_possibilities_for_detecting_biological_factors_hazardous_for_humans_and_animals_and_for_use_in_environmental_protection/links/56fd6b1008ae1408e15b2eb6.pdf High-throughput microarray mapping of cell wall polymers in roots and tubers during the viscosity reducing process. Yuhong Huang, William G. Willats, Lene Lange, Yanling Jin, Yang Fang, Armando A. Salmeán, Henriette L. Pedersen, Peter Kamp Busk, and Hai Zhao. Biotechnology and Applied Biochemistry, March-April 2016; 63(2):178-189 (MGII) Controllable heparin-based comb copolymers and their self-assembled nanoparticles for gene delivery. Jing-Jun Nie, Weiyi Zhao, Hao Hu, Bingran Yu, and Fujian Xu. ACS Applied Materials & Interfaces, 6 April 2016; 8 (13): 8376–8385. Integrated microfluidic approach for quantitative high-throughput measurements of transcription factor binding affinities. Yair Glick, Yaron Orenstein, Dana Chen, Dorit Avrahami, Tsaffrir Zor, Ron Shamir, and Doron Gerber.

  • Nucleic Acids Research, 7 April 2016; 44(6): e51, 13 pp. (MG610) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824076/ Reaction vessel for carrying out array processes. Inventors: Torsten Schulz, Eugen Ermantraut, Ralf Ehricht, Klaus-Peter Möbius, Gerd Wagner, Joachim Fischer, and Thomas Ellinger. United States Patent: US 9310291 B2, Publication Date: 12 April 2016. (MGII) https://www.google.com/patents/US9310291 A microfluidic platform for transcription-and amplification-free detection of zepto-mole amounts of nucleic acid molecules. Reinhard Mayr, Michaela Haider, Roland Thünauer, Thomas Haselgrübler, Gerhard J. Schütz, Alois Sonnleitner, and Jan Hesse. Biosensors and Bioelectronics, 15 April 2016; 78: 1-6. (MGII) Pathogen receptor discovery with a microfluidic human membrane protein array. Yair Glick, Nir Drayman, Michal Pellach, Gregory Neveu, Jim Boonyaratanakornkit, Dorit Avrahami, Shirit Einav, Ariella Oppenheim, and Doron Gerber. Proceedings of the National Academy of Sciences, 19 April 2016; 113(16): 4344–4349 (MG 610) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843447/pdf/pnas.201518698.pdf Bacterium for use as a probiotic for nutritional and medical applications. Inventors: Denise Kelly, and Imke Mulder. United States Patent: US 9314489 B2, Publication Date: 19 April 2016. (MGII TAS) https://www.google.com/patents/US9314489 UCP1 (thermogenin) - inducing agents for use in the treatment of a disorder of the energy homeostasis. Inventors: Marcel Scheideler, Michael Karbiener, Ez-Zoubir Amri, Gérard Ailhaud, and Christian Dani. United States Patent: US 9320756 B2, Publication Date: 26 April 2016. (MGII) https://www.google.com/patents/US9320756 Micro-RNAs expression signature for determination of tumors origin. Inventors: Nitzan Rosenfeld, Shai Rosenwald, Iris Barshack, and Dvora Nass. U.S. Patent Application: 2016/0115546 A1, Publication Date: 28 April 2016. (MGII) http://www.freepatentsonline.com/y2016/0115546.html An overview of innovations and industrial solutions in Protein Microarray Technology. Shabarni Gupta, K. P. Manubhai, Vishwesh Kulkarni, and Sanjeeva Srivastava. Proteomics, April 2016; 16(8): 1297–1308. (MGII) Protein Microarrays in Neurodegenerative Diseases. Pablo San Segundo-Acosta, María Garranzo-Asensio, Ana Montero-Calle, Carmen Oeo-Santos, Mayte Villalba, Ana Guzman-Aranguez, and Rodrigo Barderas. Neuromethods, 2016; 127 (Current Proteomic Approaches Applied to Brain Function): 43-62 (MGII) Microbial glycans as a target of human intelectin. Inventors: Laura L. Kiessling, Darryl A. Wesener, and Kittikhun Wangkanont. U.S. Patent Application: 2016/0131649 A1, Publication Date: 12 May 2016. (MGII) http://www.freepatentsonline.com/y2016/0131649.html

  • Gene expression signature for classification of kidney tumors. Inventors: Nitzan Rosenfeld, Yael Spector, Eddie Friedman, and Zohar Dotan. United States Patent: US 9340823 B2, Publication Date: 17 May 2016. (MGII) https://www.google.com/patents/US9340823 Analysis of the interaction between chromosomal replication and transposition mediated by sliding clamps Héctor Díaz Maldonado PhD Theses, 20 May 2016; Universidad Autónoma de Madrid, 184 pp (MG TAS II) https://repositorio.uam.es/handle/10486/673012 A miniaturized glycan microarray assay for assessing avidity and specificity of influenza A virus hemagglutinins. Ryan McBride, James C. Paulson, and Robert P. de Vries. JoVE (Journal of Visualized Experiments), 29 May 2016; 111: e53847. (MGII) https://www.jove.com/video/53847/a-miniaturized-glycan-microarray-assay-for-assessing-avidity DNA polymerase-α regulates the activation of type I interferons through cytosolic RNA: DNA synthesis Petro Starokadomskyy, Terry Gemelli, Jonathan J. Rios, Chao Xing, Richard C. Wang, Haiying Li, Vladislav Pokatayev et al. Igor Dozmorov, Shaheen Khan, Naoteru Miyata, Guadalupe Fraile, Prithvi Raj, Zhe Xu, Zigang Xu, Lin Ma, Zhimiao Lin, Huijun Wang, Yong Yang, Dan Ben-Amitai, Naama Orenstein, Huda Mussaffi, Eulalia Baselga, Gianluca Tadini, Eyal Grunebaum, Adrijan Sarajlija, Konrad Krzewski, Edward K Wakeland, Nan Yan, Maria Teresa de la Morena, Andrew R Zinn & Ezra Burstein Nature Immunology, May 2016; 17(5): 495–504. (MGII 610) http://www.nature.com/ni/journal/v17/n5/full/ni.3409.html Exploring host-pathogen interactions through genome wide protein microarray analysis. Luigi Scietti, Katia Sampieri, Irene Pinzuti, Erika Bartolini, Barbara Benucci, Alessia Liguori, Andreas F. Haag, Paola Lo Surdo, Werner Pansegrau, Vincenzo Nardi-Dei, Laura Santini, Seguinde Arora, Xavier Leber, Simonetta Rindi, Silvana Savino, Paolo Costantino, Domenico Maione, Marcello Merola, Pietro Speziale, Matthew J. Bottomley, Fabio Bagnoli, Vega Masignani, Mariagrazia Pizza, Meike Scharenberg, Jean-Marc Schlaeppi, Mikkel Nissum, and Sabrina Liberatori Scientific Reports, 15 June 2016; 6: 27996, 14 pp. (MGII) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908583/ Immunological detection of Cronobacter and Salmonella in powdered infant formula by plasmonic label-free assay. Alexandra Morlay, Félix Piat, Thibaut Mercey, and Yoann Roupioz. Letters in Applied Microbiology, June 2016; 62(6): 459-465. (MGII 600) The mannose receptor negatively modulates the Toll-like receptor 4–aryl hydrocarbon receptor–indoleamine 2, 3-dioxygenase axis in dendritic cells affecting T helper cell polarization. Fabián Salazar, Laurence Hall, Ola H. Negm, Dennis Awuah, Patrick J. Tighe, Farouk Shakib, and Amir M. Ghaemmaghami. Journal of Allergy and Clinical Immunology, June 2016; 137(6): 1841-1851. (MG 610) http://s3.amazonaws.com/academia.edu.documents/40951325/JACI_paper_1215.pdf?AWSAccessKeyId=AKIAJ56TQJRTWSMTNPEA&Expires=1466609545&Signature=gXM4Q36B9kbMV6lQ%2BhhXztHTY

  • m8%3D&response-content-disposition=inline%3B%20filename%3DThe_mannose_receptor_negatively_modulate.pdf Human Blood Autoantibodies in the Detection of Colorectal Cancer. Ola H. Negm, Mohamed R. Hamed, Robert E. Schoen, Richard L. Whelan, Robert J. Steele, John Scholefield, Elizabeth M. Dilnot, HMC Shantha Kumara, John FR Robertson, and Herbert F. Sewell. PLoS One, 6 July 2016; 11(7): e0156971, 14 pp. (MGII) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156971 Protein Profiling Gastric Cancer and Neighboring Control Tissues Using High-Content Antibody Microarrays. Martin Sill, Christoph Schröder, Ying Shen, Aseel Marzoq, Radovan Komel, Jörg D. Hoheisel, Henrik Nienhüser, Thomas Schmidt, and Damjana Kastelic. Microarrays, 8 July 2016; 5(3): 19, 12 pp. (MGII) http://www.mdpi.com/2076-3905/5/3/19/htm Label-and amplification-free electrochemical detection of bacterial ribosomal RNA. Grace Henihan, Holger Schulze, Damion K. Corrigan, Gerard Giraud, Jonathan G. Terry, Alison Hardie, Colin J. Campbell, Anthony J. Walton, Jason Crain, Ronald Pethig, Kate E. Templeton, Andrew R. Mount, Till T. Bachmann Biosensors and Bioelectronics, 15 July 2016; 81: 487-494. (MGII) Identifizierung und Charakterisierung neuer antimykotischer Substanzen gegen humanpathogene Pilze Petra Doris Keller PhD Theses, 1 August 2016; Universität Stuttgart, 203 pp. (MGII) https://elib.uni-stuttgart.de/bitstream/11682/8997/3/Dissertation_Petra_Doris_Keller.pdf Compositions and methods for treatment of melanoma. Inventors: Eva Hernando, Moshe Hoshen, Iman Osman, Avital Gaziel-Sovran, and Miguel F. Segura. United States Patent: US 9421218 B2, Publication Date: 23 August 2016. (MGII) https://www.google.com/patents/US9421218 Cross reactivity among the swine mycoplasmas as identified by protein microarray. Andrew C. Petersen, David C. Oneal, Janice R. Seibel, Kylie Poel, Courtney L. Daum, Steven P. Djordjevic, and F. Chris Minion. Veterinary Microbiology, 30 August 2016; 192: 204-212. (MGII) Identification of novel transcriptional regulators of Zat12 using comprehensive yeast one-hybrid screens. Bat-Hen Ben Daniel, Esther Cattan, Chaim Wachtel, Dorit Avrahami, Yair Glick, Asaf Malichy, Doron Gerber, and Gad Miller. Physiologia Plantarum, August 2016; 157(4): 422-441. (MG 610) Application of subtracted gDNA microarray-assisted Bulked Segregant Analysis for rapid discovery of molecular markers associated with day-neutrality in strawberry (Fragaria x ananassa). Mian Chee Gor, Nitin Mantri, and Edwin Pang. Scientific Reports, 2 September 2016; 6: 32551, 12 pp. (MGII Compact) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009313/pdf/srep32551.pdf

  • Reverse Phase Protein Arrays for Compound Profiling. Nathan Moerke, and Mohammad Fallahi-Sichani. Current Protocols in Chemical Biology, 13 September 2016; 8(3): 179-196. SMAD4 loss enables EGF, TGFβ1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells. Stefania Moz, Daniela Basso, Dania Bozzato, Paola Galozzi, Filippo Navaglia, Ola H. Negm, Giorgio Arrigoni, Carlo-Federico Zambon, Andrea Padoan, Paddy Tighe, Ian Todd, Cinzia Franchin, Sergio Pedrazzoli, Leonardo Punzi, Mario Plebani Oncotarget, 16 September 2016; 7(43): 69927-69944. (MG 610) https://www.researchgate.net/profile/Sergio_Pedrazzoli/publication/309636239_SMAD4_loss_enables_EGF_TGFb1_and_S100A8A9_induced_activation_of_critical_pathways_to_invasion_in_human_pancreatic_adenocarcinoma_cells/links/581db3fc08aeccc08aee5a4e.pdf Utilisation of antibody microarrays for the selection of specific and informative antibodies from recombinant library binders of unknown quality. Janek Kibat, Thomas Schirrmann, Matthias J. Knape, Saskia Helmsing, Doris Meier, Michael Hust, Christoph Schröder, Daniela Bertinetti, Gerhard Winter, Khalid Pardes, Mia Funk, Andrea Vala, Nathalia Giese, Friedrich W. Herberg, Stefan Dübel, Jörg D. Hoheisel New Biotechnology, 25 September 2016; 33(5A): 574–581 (MGII 610) http://www.sciencedirect.com/science/article/pii/S187167841500271X Bacterium for use as a probiotic for nutritional and medical applications. Inventors: Denise Kelly, and Imke Mulder. U.S. Patent Application: 2016/0279177 A1, Publication Date: 29 September 2016; (MGII) https://www.google.com/patents/US20160279177 Gene expression profiling identifies distinct molecular subgroups of leiomyosarcoma with clinical relevance. Yin-Fai Lee, Toby Roe, D. Chas Mangham, Cyril Fisher, Robert J. Grimer, and Ian Judson. British Journal of Cancer, 11 October 2016; 115(8): 1000-1007. (MG II) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061910/pdf/bjc2016280a.pdf Ucp1 (thermogenin)-inducing agents for use in the treatment of a disorder of the energy homeostasis. Inventors: Marcel Scheideler, Michael Karbiener, Ez-Zoubir Amri, Gérard Ailhaud, and Christian Dani. U.S. Patent Application: 2016/0298115 A1, Publication Date: 13 October 2016; (MGII) https://www.google.com/patents/US20160298115 SMAD4 loss enables EGF, TGFβ1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells. Stefania Moz, Daniela Basso, Dania Bozzato, Paola Galozzi, Filippo Navaglia, Ola H. Negm, Giorgio Arrigoni, Carlo-Federico Zambon, Andrea Padoan, Paddy Tighe, Ian Todd, Cinzia Franchin, Sergio Pedrazzoli, Leonardo Punzi, and Mario Plebani Oncotarget, 25 October 2016; 7(43): 69927-69944. (MG 610) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342525/ Reagents and Methods for miRNA Expression Analysis and Identification of Cancer Biomarkers. Inventors: Paul Gerald Ahlquist, Srikumar Sengupta, Johan Arie Den Boon, Bill Sugden, and Michael Abbott Newton. U.S. Patent Application: 2016/0319364 A1, Publication Date: 3 November 2016; (MGII)

  • https://www.google.com/patents/US20160319364 Compositions and methods for treatment of ovarian cancer. Inventor: Noga Yerushalmi United States Patent: US 9487781 B2, Publication Date: 8 November 2016; (MGII) https://www.google.com/patents/US9487781 Targeting microRNAs for the treatment of liver cancer. Inventors: C. Frank Bennett, Ayelet Chajut, Christine Esau, Eric Marcusson, and Noga Yerushalmi. United States Patent: US 9506062 B2, Publication Date: 29 November 2016; (MGII) https://www.google.com/patents/US9506062 A microfluidic multiwell chip for enzyme-free detection of mRNA from few cells. Michaela Haider, Bozhi Ji, Thomas Haselgrübler, Alois Sonnleitner, Fritz Aberger, and Jan Hesse. Biosensors and Bioelectronics, 15 December 2016; 86: 20-26. (MGII) A Combinatory Antibody–Antigen Microarray Assay for High-Content Screening of Single-Chain Fragment Variable Clones from Recombinant Libraries. Nina Persson, Bo Jansson, Nicolai Stuhr-Hansen, András Kovács, Charlotte Welinder, Lena Danielsson, and Ola Blixt. PLoS One, 21 December 2016; 11(12): e0168761, 15 pp. (MGII) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168761 Methods of isolating distinct pancreatic cell types. Inventors: Michael D. Walker, Yoav Soen, and Revital Sharivkin. United States Patent: US 9526749 B2, Publication Date: 27 December 2016. (MG) https://www.google.com/patents/US9526749 Insights into the degradation capacities of Amycolatopsis tucumanensis DSM 45259 guided by microarray data. Natalia Bourguignon, Rafael Bargiela, David Rojo, Tatyana N. Chernikova, Sara A. López de Rodas, Jesús García-Cantalejo, Daniela J. Näther, Peter N. Golyshin, Coral Barbas, Marcela Ferrero, Manuel Ferrer World Journal of Microbiology and Biotechnology, December 2016; 32(12): 201. (MG TAS II) Low-Cost Peptide Microarrays for Mapping Continuous Antibody Epitopes. Ryan McBride, Steven R. Head, Phillip Ordoukhanian, and Mansun Law. Methods Molecular Biology, 2016; 1352 (Peptide Microarrays: Methods & Protocols): 67-83. (MGII 600) Screening for Host Factors Directly Interacting with RSV Protein: Microfluidics. Sarit Kipper, Dorit Avrahami, Monika Bajorek, and Doron Gerber. Methods Molecular Biology, 2016; 1442 (Human Respiratory Syncytial Virus): 165-174. (MG 610) Investigation the effects of cigarette smoke on immunoglobulin levels in serum and saliva samples of smoker and non-smoker subjects using antibody-microarray technology. Nesrin Tarbiah PhD Theses, December 2016; University of Nottingham, 172 pp. (MGII 600) http://eprints.nottingham.ac.uk/43488/1/Investigation%20the%20Effects%20of%20Cigarette%20Smoke%20on%20Immunoglobulin%20Levels%20in%20Serum%20and%20Saliva%20Samples%20of%20Smoker%20and%20Non-Smoker%20Subjects%20.pdf

  • Protein Microarrays in Neurodegenerative Diseases. Pablo San Segundo-Acosta, María Garranzo-Asensio, Ana Montero-Calle, Carmen Oeo-Santos, Mayte Villalba, Ana Guzman-Aranguez, and Rodrigo Barderas. Neuromethods, 2016; 127 (Current Proteomic Approaches Applied to Brain Function): 43-62 (MGII) Development of electrochemical platform for DNA sensing. Wilmer Alfonso Pardo PhD Theses, 2016; Universitat de Barcelona, Spain, 192 pp. (MGII) http://www.tdx.cat/bitstream/handle/10803/397662/WILMER%20A%20.%20PRADO_Tesis_impresion.PDF?sequence=2 Biomarkers and Metabolic Patterns in the Sediments of Evolving Glacial Lakes as a Proxy for Planetary Lake Exploration. Víctor Parro, Yolanda Blanco, Fernando Puente-Sánchez, Luis A. Rivas, Mercedes Moreno-Paz, Alex Echeverría, Guillermo Chong-Díaz, Cecilia Demergasso, and Nathalie A. Cabrol. Astrobiology, 28 November 2016; ahead of print. (MG TAS II) http://online.liebertpub.com/doi/pdf/10.1089/ast.2015.1342 2015. Formation of iron-rich shelled structures by microbial communities. David C. Fernández-Remolar, Joan Santamaría, Ricardo Amils, Victor Parro, D. Gómez-Ortíz, Matthew RM Izawa, Neil R. Banerjee, Raúl Pérez Rodríguez, Nuria Rodríguez, and Nieves López-Martínez. Journal of Geophysical Research: Biogeosciences, 7 January 2015; 120(1): 147-168. (MGII) https://www.researchgate.net/profile/David_Fernandez-Remolar/publication/270547219_Formation_of_iron-rich_shelled_structures_(IRSS)_by_microbial_communities/links/55146cba0cf283ee0835e5ab.pdf An Autoantibody Based Protein Microarray Blood Test to Enhance the Specificity of a Negative Screening Mammogram. T. M. Allweis, L. Strauss, Z. Malyutin, A. Bassein Kapov-Kagan, I. Novikov, T. B. Bevers, S. Iacobelli, M. T. Sandri, A. Bitterman, P. Engelman, B. Piura, M. Rosenberg, G. Yahalom Advances in Breast Cancer Research, 22 January 2015; 4(1): 22-38. (MGII) http://file.scirp.org/Html/3-2470090_53458.htm Formation of iron-rich shelled structures (IRSS) by microbial communities. David C. Fernández-Remolar, Joan Santamaría, Ricardo Amils, Victor Parro, D. Gómez-Ortíz, Matthew RM Izawa, Neil R. Banerjee, Raúl Pérez Rodríguez, Nuria Rodríguez, and Nieves López-Martínez. Journal of Geophysical Research: Biogeosciences, 28 January 2015; 120(1): 147-167 (MGII TAS) http://www.researchgate.net/profile/David_Fernandez-Remolar/publication/270547219_Formation_of_iron-rich_shelled_structures_(IRSS)_by_microbial_communities/links/55146cba0cf283ee0835e5ab.pdf Multi-omics analysis identifies genes mediating the extension of cell walls in the Arabidopsis thaliana root elongation zone. Michael H. Wilson, Tara J. Holman, Iben Sørensen, Ester Cancho-Sanchez, Darren M. Wells, Ranjan Swarup, J. Paul Knox, William G. T. Willats, Susana Ubeda-Tomás, Michael Holdsworth, Malcolm J. Bennett, Kris Vissenberg, and T. Charlie Hodgman

  • Frontiers in Cell and Developmental Biology, 20 February 2015; 3: 10, 12pp. (MGII) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335395/ Gene expression in the mammary gland of the tammar wallaby during the lactation cycle reveals conserved mechanisms regulating mammalian lactation. C. J. Vander Jagt, J. C. Whitley, B. G. Cocks, and M. E. Goddard. Reproduction, Fertility and Development, 23 February 2015; 28(9): 1241-1257. (MGII) http://www.publish.csiro.au/index.cfm?paper=RD14210 Functional proteomics screen enables enrichment of distinct cell types from human pancreatic islets Revital Sharivkin, Michael D. Walker, and Yoav Soen. PLoS One, 23 February 2015; 10(2): e0115100, 13 pp. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115100 Synthetic secondary chromosomes in Escherichia coli based on the replication origin of chromosome II in Vibrio cholerae Sonja J. Messerschmidt, Franziska S. Kemter, Daniel Schindler, and Torsten Waldminghaus. Biotechnology Journal, February 2015; 10(2): 302-314 http://www.researchgate.net/profile/Torsten_Waldminghaus/publication/267628231_Synthetic_secondary_chromosomes_in_Escherichia_coli_based_on_the_replication_origin_of_chromosome_II_in_Vibrio_cholerae/links/547ef7da0cf2d2200edeb296.pdf The mammalian target of rapamycin complex 1 (mTORC1) in breast cancer: the impact of oestrogen receptor and HER2 pathways. Dena A. Jerjees, Ola H. Negm, M. Layth Alabdullah, Sameer Mirza, Methaq Alkaabi, Mohamed R. Hameed, Rezvan Abduljabbar, Abir Muftah, Chris C. Nolan, Andrew R. Green, Patrick J. Tighe, Vimla Band, Ian O. Ellis, Emad A. Rakha Breast Cancer Research and Treatment, February 2015; 150(1): 91-103. (MG610) https://www.researchgate.net/profile/Andrew_Green6/publication/272624489_The_mammalian_target_of_rapamycin_complex_1_(mTORC1)_in_breast_cancer_the_impact_of_oestrogen_receptor_and_HER2_pathways/links/55b6045d08ae092e9655ad63.pdf Polypeptide and immune modulation. Inventors: Denise Kelly, Angela Patterson, Edouard Monnais, and Imke Mulder. U.S. Patent Application: 20150071957 A1, Publication Date: 12 March 2015; (MGII TAS) https://www.google.com/patents/US20150071957 Fachgebiet Protein Modelling Identifizierung transkriptionell aktivierter humaner endogener Retroviren (HERVs) in Tumorerkrankungen Ingmar-Ernst Göttesdorfer PhD Theses, 18 March 2015; der Technischen Universität München, 166 pp. (MGII) http://mediatum.ub.tum.de/doc/1242849/1242849.pdf Ex vivo and in vitro production of pro-inflammatory cytokines in Blau syndrome. P. Galozzi, O. Negm, E. Greco, N. Alkhattabi, A. Gava, P. Sfriso, L. Fairclough, I. Todd, P. Tighe, L. Punzi. Reumatismo, 31 March 2015; 66(4): 277-284. (MGII) (we have pdf-file) The novel S59P mutation in the TNFRSF1A gene identified in an adult onset TNF receptor associated periodic syndrome (TRAPS) constitutively activates NF-κB pathway.

  • Eliana Greco, Ada Aita, Paola Galozzi, Alessandra Gava, Paolo Sfriso, Ola H. Negm, Patrick Tighe, Francesco Caso, Filippo Navaglia, Emanuela Dazzo, Marzia De Bortoli, Alessandra Rampazzo, Laura Obici, Simona Donadei, Giampaolo Merlini, Mario Plebani, Ian Todd, Daniela Basso, Leonardo Punzi Arthritis Research & Therapy, 3 April 2015; 17(1): 93. 15 pp. (MG610) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416318/ Carbohydrate microarray for the detection of glycan-protein interactions using metal-enhanced fluorescence. Jie Yang, Anne Moraillon, Aloysius Siriwardena, Rabah Boukherroub, François Ozanam, Anne Chantal Gouget-Laemmel, and Sabine Szunerits. Analytical Chemistry, 7 April 2015; 87 (7): 3721–3728 (MGII) Composition and methods for modulating cell proliferation and cell death. Inventors: Moshe Oren, Nina Raver-Shapira, Efi Marciano, and Yael Spector. United States Patent: US 9006206 B2, Publication Date: 14 April 2015; (MGII) https://www.google.com/patents/US9006206 Oxidative stress, mitochondrial damage, and cores in muscle from calsequestrin-1 knockout mice. Cecilia Paolini, Marco Quarta, Lan Wei-LaPierre, Antonio Michelucci, Alessandra Nori, Carlo Reggiani, Robert T. Dirksen, and Feliciano Protasi. Skeletal Muscle, 18 April 2015; 5(1): 10, 17 pp. (MGII) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464246/ Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer. Rezvan Abduljabbar, Ola H. Negm, Chun-Fui Lai, Dena A. Jerjees, Methaq Al-Kaabi, Mohamed R. Hamed, Patrick J. Tighe, Lakjaya Buluwela, Abhik Mukherjee, Andrew R. Green, Simak Ali, Emad A. Rakha, Ian O. Ellis Breast Cancer Research and Treatment, April 2015; 150(2): 335-346. (MG610) https://www.researchgate.net/publication/273467268_Clinical_and_biological_significance_of_glucocorticoid_receptor_GR_expression_in_breast_cancer Comparative analysis of genetic variation in Kava (Piper methysticum) assessed by SSR and DArT reveals zygotic foundation and clonal diversification. Henri VandenBroucke, Pierre Mournet, Roger Malapa, Jean Christophe Glaszmann, Hana Chair, and Vincent Lebot. Genome, April 2015; 58(1): 1-11 (MGII) Microarray Core Facility: Array Production. In: The Scripps Research Institute. Web page. Spring 2015; (MGII) http://www.scripps.edu/california/research/dna-array/custom/arrayer.html Bacterium for use as a probiotic for nutritional and medical applications. Inventors: Denise Kelly, and Imke Mulder. U.S. Patent Application: 20150132264 A1; Publication Date: 14 May 2015; (MGII TAS) https://www.google.com/patents/US20150132264 Microarray transcriptional profiling of Arctic Mesorhizobium strain N33 at low temperature provides insights into cold adaption strategies. Abdollah-Fardin Ghobakhlou, Anne Johnston, Linda Harris, Hani Antoun, and Serge Laberge. BMC Genomics, 15 May 2015; 16(1): 383, 14 pp. (MG Compact)

  • http://www.biomedcentral.com/1471-2164/16/383 Point-of-care diagnostics for ricin exposure. Mohamed Lemine Youba Diakite, Jérôme Rollin, Dorothée Jary, Jean Berthier, Chantal Mourton-Gilles, Didier Sauvaire, Cathy Philippe, Guillaume Delapierre, and Xavier Gidrol. Lab on a Chip, 21 May 2015; 15(10): 2308-2317. (MGII) Methods of isolating distinct pancreatic cell types. Inventors: Michael Walker, Yoav Soen, and Revital Sharivkin. U.S. Patent Application: 2015/0157668 A1, Publication Date: 11 June 2015; http://www.freepatentsonline.com/y2015/0157668.html Silicon nanonets for biological sensing applications with enhanced optical detection ability. P. Serre, V. Stambouli, M. Weidenhaupt, T. Baron, and C. Ternon. Biosensors and Bioelectronics, 15 June 2015; 68: 336-342. (MGII) https://elsevier.conference-services.net/viewsecurePDF.asp?conferenceID=3774&loc=files&type=paper&abstractID=831177 http://www.sciencedirect.com/science/article/pii/S0956566315000135 Tetrandrine reverses human cardiac myofibroblast activation and myocardial fibrosis. Guoqi Teng, Daniyil Svystonyuk, Holly EM Mewhort, Jeannine D. Turnbull, Darrell D. Belke, Henry J. Duff, and Paul WM Fedak. American Journal of Physiology-Heart & Circulatory Physiology, 15 June 2015; 308(12): H1564-H1574. MicroRNA biomarkers for human breast and lung cancer. Inventors: Ethan Dmitrovsky, Xi Liu, Sarah Freemantle, Lorenzo F. Sempere, Charles Cole, Sakari Kauppinen, Mads Bak, and Mette Christensen. United States Patent: US 9056135 B2, Publication Date: 16 June 2015; (MGII) https://www.google.com/patents/US9056135 Design and fabrication of a flexible MEMS-based electro-mechanical sensor array for breast cancer diagnosis. Hardik J. Pandya, Kihan Park, and Jaydev P. Desai. Journal of Micromechanics and Microengineering, 23 June 2015; 25(7): 075025. Genome-scale resources for Thermoanaerobacterium saccharolyticum. Devin H. Currie, Babu Raman, Christopher M. Gowen, Timothy J. Tschaplinski, Miriam L. Land, Steven D. Brown, Sean F. Covalla, Dawn M Klingeman, Zamin K Yang, Nancy L Engle, Courtney M Johnson, Miguel Rodriguez, A Joe Shaw,William R Kenealy, Lee R Lynd, Stephen S Fong, Jonathan R Mielenz, Brian H Davison, David A Hogsett and Christopher D Herring BMC Systems Biology, 26 June 2015; 9(1): 30, 15 pp. (MGII) http://www.biomedcentral.com/1752-0509/9/30 Gene expression signature for classification of kidney tumors. Inventors: Nitzan Rosenfeld, Yael Spector, Eddie Friedman, Zohar Dotan, and Shai Rosenwald. United States Patent: US 9068232 B2, Publication Date: 30 June 2015; (MGII) https://www.google.com/patents/US9068232 MicroRNA signature is indicative of long term prognosis in diffuse large B-cell lymphoma.

  • Daniel Shepshelovich, Ron Ram, Orit Uziel, Michal Kushnir, Gila Lithwick-Yanai, Moshe Hoshen, Meora Feinmesser, Osnat Bairey, and Meir Lahav. Leukemia Research, June 2015; 39(6):632-637. (MGII) Immunogenic fragments of T-cell receptor constant domains and peptides derived therefrom. Inventors: Irun R. Cohen, and Francisco J. Quintana. United States Patent: US 9078843 B2, Publication Date: 14 July 2015. https://www.google.com/patents/US9078843 Immunological Biomarkers in Postinfectious Irritable Bowel Syndrome. Brian L. Pike, Katie Ann Paden, Ashley N. Alcala, Kayla M. Jaep, Robert P. Gormley, Alexander C. Maue, Benjamin S. Christmann, Charles O. Elson, Mark S. Riddle, and Chad K. Porter. Journal of Travel Medicine, July-August 2015; 22(4): 242-250. (MGII) Rapid Electrochemical Detection of New Delhi Metallo-beta-lactamase Genes To Enable Point-of-Care Testing of Carbapenem-Resistant Enterobacteriaceae. Jimmy Ming-Yuan Huang, Grace Henihan, Daniel Macdonald, Annette Michalowski, Kate Templeton, Alan P. Gibb, Holger Schulze, and Till T. Bachmann. Analytical Chemistry, 4 August 2015; 87(15): 7738-7745. (MGII) http://www.research.ed.ac.uk/portal/files/21536349/Rapid_electrochemical_detection_of_New_Delhi_metallo_beta_lactamase_genes_to_enable_point_of_care_testing_of_carbapenem_resistant_Enterobacteriaceae.pdf Method for detecting a target nucleic acid comprising two portions using probes having a first portion complementary to the first portion of the target nucleic acid and a second portion substantially complementary to the second portion of the target nucleic acid. Inventors: Shlomit Gilad, and Esther Meiri. United States Patent: US 9115389 B2, Publication Date: 25 August 2015; (MGII) https://www.google.com/patents/US9115389 Transposase interaction with the β sliding clamp: effects on insertion sequence proliferation and transposition rate. Héctor Díaz-Maldonado, Manuel J. Gómez, Mercedes Moreno-Paz, Patxi San Martín-Úriz, Ricardo Amils, Víctor Parro, and Francisco J. López de Saro. Scientific Reports, 26 August 2015; 5: 13329, 13 pp. (MG TASII) http://www.nature.com/articles/srep13329 An integrated genome-wide approach to discover deregulated microRNAs in non-small cell lung cancer: Clinical significance of miR-23b-3p deregulation. Shahnaz Begum, Masamichi Hayashi, Takenori Ogawa, Fayez J. Jabboure, Mariana Brait, Evgeny Izumchenko, Sarit Tabak, Steven A. Ahrendt, William H. Westra, Wayne Koch, David Sidransky & Mohammad O. Hoque Scientific Reports, 28 August 2015; 5: 13236, 16 pp. (MGII) http://www.nature.com/articles/srep13236 Recognition of microbial glycans by human intelectin-1. Darryl A. Wesener, Kittikhun Wangkanont, Ryan McBride, Xuezheng Song, Matthew B. Kraft, Heather L. Hodges, Lucas C. Zarling, Rebecca A Splain, David F Smith, Richard D Cummings, James C Paulson, Katrina T Forest & Laura L Kiessling Nature Structural & Molecular Biology, August 2015; 22(8): 603-610. (MGII)

  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526365/ Host factors and broadly neutralizing antibodies in South African women infected with HIV-1 subtype C. Cathrine Scheepers PhD Theses, 3 September 2015; University of the Witwatersrand, Johannesburg, 207 pp. (MGII) http://wiredspace.wits.ac.za/handle/10539/19680 FHL2 switches MITF from activator to repressor of Erbin expression during cardiac hypertrophy. Inbal Rachmin, Eden Amsalem, Eliahu Golomb, Ronen Beeri, Dan Gilon, Pengfei Fang, Hovav Nechushtan, Gillian Kay, Min Guo, Peter Li Yiqing, Roger S.-Y. Foo, David E. Fisher, Ehud Razin, Sagi Tshori International Journal of Cardiology, 15 September 2015; 195: 85-94. (MGII) https://www.researchgate.net/profile/Gillian_Kay/publication/277405857_FHL2_switches_MITF_from_activator_to_repressor_of_Erbin_expression_during_cardiac_hypertrophy/links/556d659b08aeccd7773bf44c.pdf Compositions and methods for the diagnosis and prognosis of mesothelioma. Inventors: Shai Rosenwald, Hila Benjamin, and Nitzan Rosenfeld. United States Patent: US 9133522 B2, Publication Date: 15 September 2015; (MGII) https://www.google.com/patents/US9133522 Two of Them Do It Better: Novel Serum Biomarkers Improve Autoimmune Hepatitis Diagnosis. Saveria Mazzara, Antonia Sinisi, Angela Cardaci, Riccardo Lorenzo Rossi, Luigi Muratori, Sergio Abrignani, and Mauro Bombaci. PLoS One, 16 September 2015; 10(9): e0137927, 20 pp. (MGII) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137927 Methods of identifying glycopeptides recognized by disease-associated auto-antibodies. Inventor: Edward Nudelman United States Patent: US 9140692 B1, Publication Date: 22 September 2015; https://www.google.com/patents/US9140692 Profiling Humoral Immune Responses to Clostridium difficile-Specific Antigens by Protein Microarray Analysis. Ola H. Negm, Mohamed R. Hamed, Elizabeth M. Dilnot, Clifford C. Shone, Izabela Marszalowska, Mark Lynch, Christine E. Loscher, Laura J. Edwards, Patrick J. Tighe, Mark H. Wilcox and Tanya M. Monagha Clinical and Vaccine Immunology, September 2015; 22(9): 1033-1039. (MG610) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550668/ A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation in response to radiation. Sami Benzina, Amandine Pitaval, Claudie Lemercier, Celine Lustremant, Vincent Frouin, Ning Wu, Alexandre Papine, Françoise Soussaline, Paul-Henri Romeo, and Xavier Gidrol. Cellular and Molecular Life Sciences, September 2015; 72(18): 3559-3573. (MGII) http://link.springer.com/article/10.1007/s00018-015-1901-7/fulltext.html Ruminococcal cellulosome systems from rumen to human.

  • Yonit Ben David, Bareket Dassa, Ilya Borovok, Raphael Lamed, Nicole M. Koropatkin, Eric C. Martens, Bryan A. White, Annick Bernalier-Donadille, Sylvia H Duncan, Harry J. Flint, Edward A. Bayer and Sarah Moraïs Environmental Microbiology, September 2015; 17(9): 3407-3426. (MG610) http://www.researchgate.net/publication/274459590_Ruminococcal_cellulosome_systems_from_rumen_to_human_Human_ruminococcal_cellulosome A pneumococcal protein array as a platform to discover serodiagnostic antigens against infection. Alfonso Olaya-Abril, Irene Jiménez-Munguía, Lidia Gómez-Gascón, Ignacio Obando, and Manuel J. Rodríguez-Ortega. Molecular & Cellular Proteomics, 1 October 2015; 14(10): 2591-2608. (MG610) Integrated microfluidics for protein modification discovery. Meirav Noach-Hirsh, Hadas Nevenzal, Yair Glick, Evelin Chorni, Dorit Avrahami, Efrat Barbiro-Michaely, Doron Gerber, and Amit Tzur. Molecular & Cellular Proteomics, 1 October 2015; 14(10): 2824-2832. (MG610) Targeting microRNAs for the treatment of liver cancer. Inventors: C. Frank Bennett, Ayelet Chajut, Christine Esau, Eric Marcusson, and Noga Yerushalmi. United States Patent: US 9150857 B2, Publication Date: 6 October 2015; (MGII) https://www.google.com/patents/US9150857 On-the-Spot Immobilization of Quantum Dots, Graphene Oxide, and Proteins via Hydrophobins. Alfredo M. Gravagnuolo, Eden Morales-Narváez, Charlene Regina Santos Matos, Sara Longobardi, Paola Giardina, and Arben Merkoçi. Advanced Functional Materials, 14 October 2015; 25(38): 6084-6092. (MGII) Automatisiertes Mikrofluidik-System mit optischem Aufbau zur Untersuchung von Peptid-Antikörper-Wechselwirkungen im Arrayformat. L. K. Weber, A. Fischer, M. Soehindrijo, T. C. Förtsch, C. Bojnicic-Kninski, D. Althuon, S. M. Schillo, J. Striffler, F. F. Löffler, F. Breitling, A. Nesterov-Müller In: MikroSystemTechnik Kongress, 2015; 26-28 October 2015, Karlsruhe, (MGII) Identification of ecotype-specific marker genes for categorization of beer-spoiling Lactobacillus brevis. Jürgen Behr, Andreas J. Geißler, Patrick Preissler, Armin Ehrenreich, Angel Angelov, and Rudi F. Vogel. Food Microbiology, October 2015; 51: 130-138. DArT-based characterisation of genetic diversity in a Miscanthus collection from Poland. Jie Tang, Maurycy Daroch, Andrzej Kilian, Stanislaw Jeżowski, Marta Pogrzeba, and Michal Mos. Planta, October 2015; 242(4): 985-996. https://www.researchgate.net/profile/Michal_Mos/publication/277781414_DArT-based_characterisation_of_genetic_diversity_in_a_Miscanthus_collection_from_Poland/links/55858d6008ae7bc2f44bde44.pdf Integrated microfluidics for protein modification discovery. Meirav Noach-Hirsh, Hadas Nevenzal, Yair Glick, Evelin Chorni, Dorit Avrahami, Efrat Barbiro-Michaely, Doron Gerber, and Amit Tzur. Molecular & Cellular Proteomics, October 2015; 14(10): 2824-2832. (MG610)

  • Immunogenic fragments of t-cell receptor constant domains and peptides derived therefrom. Inventors: Irun R. Cohen, and Francisco Javier Quintana. U.S. Patent Application: 20150313977 A1, Publication Date: 5 November 2015. https://www.google.com/patents/US20150313977 Co-transcriptomes of initial interactions in vitro between streptococcus pneumoniae and human pleural mesothelial cells. Claire J. Heath, Maria del Mar Cendra, Alastair Watson, Jean-Philippe Auger, Anish Pandey, Paddy Tighe, and Myron Christodoulides. PLoS One, 13 November 2015; 10(11): e0142773, 26 pp. (MGII 600) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643877/ High-throughgput phage-display screening in array format. Paula Díez, Ricardo Jara-Acevedo, María González-González, Juan Casado-Vela, Noelia Dasilva, Quentin Lécrevisse, Raquel Bartolomé, José Carlos Claros, Alfredo González, Ricardo López, Alberto Orfao, Manuel Fuentes Enzyme and Microbial Technology, November 2015; 79-80: 34-41. (MGII) http://www.researchgate.net/profile/Paula_Diez/publication/280492466_High-throughgput_Phage-Display_Screening_in_Array_Format/links/55b65c7d08aed621de033cfc.pdf Guanine polynucleotides are self-antigens for human natural autoantibodies and are significantly reduced in the human genome. Ittai Fattal, Noam Shental, Shifra Ben-Dor, Yair Molad, Armando Gabrielli, Elisheva Pokroy-Shapira, Shirly Oren, Avi Livneh, Pnina Langevitz, Gisele Zandman-Goddard, Ofer Sarig, Raanan Margalit, Uzi Gafte, Eytan Domany and Irun R. Cohen Immunology, November 2015; 146(3): 401-410. (MG600) Human seroreactivity to gut microbiota antigens. Benjamin S. Christmann, Thomas R. Abrahamsson, Charles N. Bernstein, L. Wayne Duck, Peter J. Mannon, Göran Berg, Bengt Björkstén, Maria C. Jenmalm, and Charles O. Elson. Journal of Allergy and Clinical Immunology, November 2015; 136(5):1378-1386.e5 (MGII) Diversity Arrays Technology (DArT) Marker Platforms for Diversity Analysis and Linkage Mapping in a Complex Crop, the Octoploid Cultivated Strawberry (Fragaria× ananassa). José F. Sánchez-Sevilla, Aniko Horvath, Miguel A. Botella, Amèlia Gaston, Kevin Folta, Andrzej Kilian, Beatrice Denoyes, and Iraida Amaya. PLoS One, 16 December 2015; 10(12): e0144960, 22 pp. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682937/ Multi-scale genomic, transcriptomic and proteomic analysis of colorectal cancer cell lines to identify novel biomarkers. Romina Briffa, Inhwa Um, Dana Faratian, Ying Zhou, Arran K. Turnbull, Simon P. Langdon, and David J. Harrison. PLoS One, 17 December 2015; 10(12): e0144708, 29 pp. (MGII) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692059/ Detecting nucleic acids. Inventors: Shlomit Gilad, and Esther Meiri. U.S. Patent Application: 2015/0376695 A1, Publication Date: 31 December 2015. (MGII) http://www.freepatentsonline.com/y2015/0376695.html

  • The Glycan Array Platform as a Tool to Identify Carbohydrate Antigens. Li Xia, and Jeffrey C. Gildersleeve. Methods Molecular Biology, 2015; 1331(Carbohydrate-Based Vaccines): 27-40. (MGII) 2014. Chondroitin sulfate binding proteins and modulators thereof Inventors: Cristal I. Gama, Sarah E. Tully, Linda C. Hsieh-Wilson United States Patent: 8623610 B2; Publication Date: 7 January 2014 (MGII) https://www.google.com/patents/US8623610 High density MicroArrays on Blu-ray discs for massive screening. Tania Arnandis-Chover, Sergi Morais, Miguel Ángel González-Martínez, Rosa Puchades, and Ángel Maquieira. Biosensors and Bioelectronics, 15 January 2014; 51(1): 109-114. (MGII) (we have pdf file) Optimization of peptide arrays for studying antibodies to hepatitis C virus continuous epitopes. Tinashe B. Ruwona, Ryan Mcbride, Rebecca Chappel, Steven R. Head, Phillip Ordoukhanian, Dennis R. Burton, and Mansun Law. Journal of Immunological Methods, 15 January 2014; 402(1): 35-42. (MGII) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009380/ Antibody microarray as a proteomic tool for effective diagnosis and prediction of prognosis in cancer. Harish Srinivasan. PhD Theses, 21 January 2014; Ruperto-Carola University of Heidelberg, Germany, 98pp. (MGII) http://archiv.ub.uni-heidelberg.de/volltextserver/16167/1/Thesis%20Harish%20Srinivasan.pdf Method for the detection and/or identification of a microorganism. Inventors: Viraj N. Perera, and Benjamin N. Fry. United States Patent: 8632968 B2; Publication Date: January 21, 2014; (MGII Compact) https://www.google.com/patents/US8632968 Assessment of leaf/stem ratio in wheat straw feedstock and impact on enzymatic conversion. Heng Zhang, Jonatan U. Fangel, William GT Willats, Michael J. Selig, Jane Lindedam, Henning Jørgensen, and Claus Felby. GCB (Global Change Biology) Bioenergy, January 2014; 6(1): 90-96. (MGII) Study of the biological functions of the nonessential regulatory subunits of the protein phosphatase Glc7 in the yeast Saccharomyces cerevisiae. Jofre Ferrer-Dalmau Falgueras PhD Theses, 31 January 2014; Universitat Autònoma de Barcelona, Spain, 256 pp (MGII) http://www.tdx.cbuc.es/bitstream/handle/10803/130775/jfdf1de1.pdf?sequence=1 Screening and culturing device and methods for the use thereof Inventors: Marie Zhang, Justin Bingham, Naira Serobyan

  • U.S. Patent Application: 2014/0038847A1; Publication Date: 6 February 2014 https://www.google.com/patents/US20140038847 Lipochitin oligosaccharides immobilized through oximes in glycan Microarrays bind LysM proteins. Nicolai N. Maolanon, Mickael Blaise, Kasper K. Sørensen, Mikkel B. Thygesen, Emiliano Cló, John T. Sullivan, Clive W. Ronson, Jens Stougaard, Ola Blixt, and Knud J. Jensen. ChemBioChem, 10 February 2014; 15(3): 425-434. (MGII) Die Rolle von miRNAs in der KRAS-Onkogen-vermittelten Tumorentstehung im Ovarialepithel. Alexander Gross PhD Theses, 14 February 2014; Freie Universität Berlin, Germany, 117 pp. http://www.diss.fu-berlin.de/diss/servlets/MCRFileNodeServlet/FUDISS_derivate_000000014307/diss_a_gross.pdf Analysis of the involvement of exosomal miRNAs and proteins in the response of CRC cells to Cetuximab. Marco Maugeri PhD Theses, 14 February 2014; Università degli studi di Catania, Italy, 144 pp. (MG2) http://archivia.unict.it/handle/10761/1527 Compositions and methods for treatment of melanoma. Inventors: Eva Hernando, Moshe Hoshen, Iman Osman, Avital Gaziel-Sovran, and Miguel F. Segura. U.S. Patent Application: 20140050803 A1, Publication Date: 20 February 2014; (MGII) https://www.google.com/patents/US20140050803 Epstein–Barr virus antibodies mark systemic lupus erythematosus and scleroderma patients negative for anti-DNA. Ittai Fattal, Noam Shental, Yair Molad, Armando Gabrielli, Elisheva Pokroy-Shapira, Shirly Oren, Avi Livneh Pnina Langevitz, Rachel Pauzner, Ofer Sarig, Uzi Gafter, Eytan Domany and Irun R. Cohen Immunology, February 2014; 141(2): 276-285 (MG600) http://onlinelibrary.wiley.com/doi/10.1111/imm.12200/full New model for electron flow for sulfate reduction in Desulfovibrio alaskensis G20. Kimberly L. Keller, Barbara J. Rapp-Giles, Elizabeth S. Semkiw, Iris Porat, Steven D. Brown, and Judy D. Wall. Applied and Environmental Microbiology, February 2014; 80(3): 855-868. (MGII) http://aem.asm.org/content/80/3/855.full Method for the detection and/or identification of a microorganism. Inventors: Viraj Nawagamuwa Perera, and Benjamin Nicholas Fry US Patent Application: US 2014/0080735 A1; Publication Date: 20 March 2014; (MGII Compact) https://www.google.com/patents/US20140080735 Development of an antigen microarray for high throughput monoclonal antibody selection. Nicole Staudt, Nicole Müller-Sienerth, and Gavin J. Wright. Biochemical and Biophysical Research Communications, 21 March 2014; 445(4): 785-790. (MGII) http://www.sciencedirect.com/science/article/pii/S0006291X13020913 Particle immobilized coatings and uses thereof. Inventors: Patrick E. Guire, Kristin S. Taton, and John V. Wall.

  • United States Patent: 8679454 B2; Publication Date: 25 March 2014; (MGII) https://www.google.com/patents/US8679454 Targeting microRNAs for the treatment of liver cancer. Inventors: C. Frank Bennett, Ayelet Chajut, Christine Esau, Eric Marcusson, and Noga Yerushalmi. United States Patent: 8680067 B2; Publication Date: 25 March 2014; (MGII) https://www.google.com/patents/US8680067 Evaluation of homo-and hetero-functionally activated glass surfaces for optimized antibody arrays. María González-González, Raquel Bartolome, Ricardo Jara-Acevedo, Juan Casado-Vela, Noelia Dasilva, Sergio Matarraz, Jacinto García, J.A. Alcazar, J.M. Sayagues, Alberto Orfao, Manuel Fuentes mailto:[email protected] Analytical Biochemistry, 1 April 2014; 450: 37-45. (MGII) (we have pdf-file) Genome-wide meta-analysis of maize heterosis reveals the potential role of additive gene expression at pericentromeric loci. Alexander Thiemann, Junjie Fu, Felix Seifert, Robert T. Grant-Downton, Tobias A. Schrag, Heike Pospisil, Matthias Frisch, Albrecht E. Melchinger, and Stefan Scholten. BMC Plant Biology, 2 April 2014; 14(1): 88, 14pp. (MGII) http://www.biomedcentral.com/content/pdf/1471-2229-14-88.pdf Protein Scaffolds for Antibody Mimics and Other Binding Proteins Inventors: Dasa Lipovsek, Richard W. Wagner, Robert G. Kuimelis US Patent Application: US 2014/0094595 A1; Publication Date: 03 April 2014 https://www.google.com/patents/US20140094595 Biomarkers for autoimmune liver diseases and uses thereof. Inventors: Sergio Abrignani, Mauro Bombaci, and Chiara Zingaretti. US Patent Application: US 2014/0106987 A1; Publication Date: 17 April 2014 (MGII) https://www.google.com/patents/US20140106987 Development of a DNA-Microarray for genotyping antibiotic resistance determinants in Acinetobacter baumannii Simon Dally PhD Theses, 29 April 2014; Universität Stuttgart, Germany, 122 pp. (MGII 610) http://elib.uni-stuttgart.de/opus/volltexte/2014/9325/pdf/Dissertation_Dally.pdf Cancer-associated autoantibodies to MUC1 and MUC4-A blinded case-control study of colorectal cancer in UK collaborative trial of ovarian cancer screening. Johannes W. Pedersen, Aleksandra Gentry-Maharaj, Alexander Nøstdal, Evangelia-Ourania Fourkala, Anne Dawnay, Matthew Burnell, Alexey Zaikin, Joy Burchell, Joyce Taylor Papadimitriou, Henrik Clausen, Ian Jacobs, Usha Menon and Hans H. Wandall International Journal of Cancer, 01 May 2014; 134(9): 2180-2188. (MGII) http://onlinelibrary.wiley.com/doi/10.1002/ijc.28538/full DNA polymerase. Inventors: Philipp Holliger, Farid Ghadessy, Marc D'Abbadie US Patent Application: US 2014/0127694 A1; Publication Date: 8 May 2014 https://www.google.com/patents/US20140127694

  • Análisis de la saliva de Ornithodoros moubata y producción de antígenos recombinantes para el desarrollo de test serológicos y vacunas anti-garrapata. Verónica Díaz Martín PhD Theses, 16 May 2014; Universidad de Salamanca, Spain, 208 pp. (MGII) http://digital.csic.es/handle/10261/101385 Antisense oligonucleotides for inhibition of microRNA-21. Inventors: Joacim Elmén, Phil Kearney, and Sakari Kauppinen. United States Patent: 8,729,250, Publication Date: 20 May 2014; (MGII) https://www.google.com/patents/US8729250 Performance of a multiplexed serological microarray for the detection of antibodies against central nervous system pathogens. Anne J. Jääskeläinen, Sari M. Viitala, Satu Kurkela, Satu Hepojoki, Heidi Sillanpää, Hannimari Kallio-Kokko, Tomas Bergström Jukka Suni, Ale Närvänen, Olli Vapalahti, Antti Vaheri Journal of Microbiological Methods, May 2014; 100 (1): 27-31. (MGII) (we have pdf file) Analyse epigenetischer Effekte (microRNAs) in ehemaligen Wismutbeschäftigten. Georg Johnen, Thomas Brüning, D. G. Weber, Maria Gomolka. Vorhaben 3610S10001, May 2014; Laufzeit 01.12.2010 – 30.11.2011, 56 pp. (MG Compact) http://doris.bfs.de/jspui/bitstream/urn:nbn:de:0221-2014051311415/3/BfS_2014_3610S10001.pdf Antigen detection. Inventors: Colin Campbell, Peter Ghazal, Juraj Petrik, Janine Scott Robb United States Patent: 8748355 B2; Publication Date: 10 June 2014 (MGII) https://www.google.com/patents/US8748355 Microarray Multiplex Assay for the Simultaneous Detection and Discrimination of Influenza A and Influenza B Viruses. Mingyao Tian, Yufei Tian, Yang Li, Huijun Lu, Xiao Li, Chang Li, Fei Xue, and Ningyi Jin. Indian Journal of Microbiology, June 2014; 54(2): 211-217. (MG TAS) Prediction of recurrence of non muscle-invasive bladder cancer by means of a protein signature identified by antibody microarray analyses. Harish Srinivasan, Yves Allory, Martin Sill, Dimitri Vordos, Mohamed Saiel Saeed Alhamdani, Francois Radvanyi, Jörg D. Hoheisel, and Christoph Schröder. Proteomics, June 2014; 14(11): 1333-1342. Microbial glycan microarrays define key features of host-microbial interactions. Sean R. Stowell, Connie M. Arthur, Ryan McBride, Oren Berger, Nahid Razi, Jamie Heimburg-Molinaro, Lilian C. Rodrigues Jean-Philippe Gourdine, Alexander J Noll,Stephan von Gunten, David F Smith, Yuriy A Knirel, James C Paulson & Richard D Cummings Nature Chemical Biology, June 2014; 10(6): 470-476. Composition and methods for modulating cell proliferation and cell death. Inventors: Moshe Oren, Nina Raver-Shapira, Efi Marciano, and Yael Spector. United States Patent: US 8765702 B2; Publication Date: 1 July 2014. (MGII) https://www.google.com/patents/US8765702

  • A sensitive microfluidic platform for a high throughput DNA methylation assay. Maria Ronen, Dorit Avrahami, and Doron Gerber. Lab on a Chip, 7 July 2014; 14(13): 2354-2362. (MG610) Micromotor enhanced microarray technology for protein detection. Eden Morales-Narváez, Maria Guix, Mariana Medina-Sánchez, Carmen C. Mayorga-Martinez, and Arben Merkoçi. Small, 9 July 2014; 10(13): 2542-2548. (MGII) Single-Stranded DNA Catalyzes Hybridization of PCR-Products to Microarray Capture Probes. Simon Dally, Steffen Rupp, Karin Lemuth, Stefan C. Hartmann, Ekkehard Hiller, Susanne M. Bailer, Cornelius Knabbe, and Jan Weile. PLoS One, 15 July 2014; 9(7): e102338, 9pp. (MGII 610) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102338 Flagella interact with ionic plant lipids to mediate adherence of pathogenic Escherichia coli to fresh produce plants. Yannick Rossez, Ashleigh Holmes, Eliza B. Wolfson, David L. Gally, Arvind Mahajan, Henriette L. Pedersen, William GT Willats, Ian K. Toth, and Nicola J. Holden. Environmental Microbiology, July 2014; 16(7): 2181-2195. (MGII) (we have pdf-file) A pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS). Ola H. Negm, Heiko A. Mannsperger, Elizabeth M. McDermott, Elizabeth Drewe, Richard J. Powell, Ian Todd, Lucy C. Fairclough, and Patrick J. Tighe. European Journal of Immunology, July 2014; 44(7): 2096-2110. (MGII 610) http://onlinelibrary.wiley.com/doi/10.1002/eji.201344328/full Pattern Triggered Immunity (PTI) in Tobacco: Isolation of Activated Genes Suggests Role of the Phenylpropanoid Pathway in Inhibition of Bacterial Pathogens. Ágnes Szatmári, Ágnes Zvara, Ágnes M. Móricz, Eszter Besenyei, Erika Szabó, Péter G. Ott, László G. Puskás, and Zoltán Bozsó. PLoS One, 7 August 2014; 9(8): e102869, 16pp. (MG TAS) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102869 Involvement of MicroRNAs in the Regulation of Muscle Wasting during Catabolic Conditions. Ricardo José Soares, Stefano Cagnin, Francesco Chemello, Matteo Silvestrin, Antonio Musaro, Cristiano De Pitta, Gerolamo Lanfranchi, and Marco Sandri. Journal of Biological Chemistry, 8 August 2014; 289(32): 21909-21925. (MGII) http://www.jbc.org/content/289/32/21909.full.pdf+html Gene expression signature for classification of tissue of origin of tumor samples. Inventors: Ranit Aharonov, Nitzan Rosenfeld, and Shai Rosenwald. United States Patent: 8802599 B2, Publication Date: 12 August 2014. (MGII) https://www.google.com/patents/US8802599 Unveiling viral–host interactions within the ‘microbial dark matter’. Manuel Martínez-García, Fernando Santos, Mercedes Moreno-Paz, Víctor Parro, and Josefa Antón. Nature Communications, 14 August 2014; 5: 4542

  • Gene expression signature for classification of kidney tumors. Inventors: Nitzan Rosenfeld, Yael Spector, Eddie Friedman, and Zohar Dotan US Patent Application: US 20140243230 A1; Publication Date: 28 August 2014; (MGII) https://www.google.com/patents/US20140243230 Profile of secreted hydrolases, associated proteins, and SlpA in Thermoanaerobacterium saccharolyticum during the degradation of hemicellulose. D. H. Currie, Adam M. Guss, C. D. Herring, Richard J. Giannone, Courtney M. Johnson, Patricia K. Lankford, Steven D. Brown, R. L. Hettich, and Lee R. Lynd. Applied and Environmental Microbiology, August 2014; 80(16): 5001-5011. (MGII) http://aem.asm.org/content/80/16/5001.full Control of morphogenesis, protease secretion and gene expression in Candida albicans by the preferred nitrogen source ammonium. Nico Dunkel, Kajal Biswas, Ekkehard Hiller, Kurt Fellenberg, Somisetty V. Satheesh, Steffen Rupp, and Joachim Morschhäuser. Microbiology, August 2014; 160(8): 1599-1608. (MGII) Component-resolved diagnosis of wheat flour allergy in baker's asthma. Cristina Gómez-Casado, María Garrido-Arandia, Catia Pereira, Manuela Catarino, Víctor Parro, Alicia Armentia, Santiago Quirce Blanca Armentia,Paloma Barranco, Miguel Blanca, Paloma Campo, Araceli Díaz-Perales Journal of Allergy and Clinical Immunology, August 2014; 134(2): 480-483. (MGII TAS) Compositions and methods for prognosis and treatment of prostate cancer. Inventors: Ayelet Chajut, and Shai Rosenwald. United States Patent: 8822144 B2; Publication Date: 2 September 2014; (MGII) https://www.google.com/patents/US8822144 Composition and methods for modulating cell proliferation and cell death. Inventors: Moshe Oren, Nina Raver-Shapira, Efi Marciano, and Yael Spector. U.S. Patent Application: 2014/0256789 A1, Publication Date: 11 September 2014; (MGII) https://www.google.com/patents/US20140256789 Amplification of 2p as a genomic marker for transformation in lymphoma. Anna Kwiecinska, Koichi Ichimura, Mattias Berglund, Andrii Dinets, Luqman Sulaiman, V. Peter Collins, Catharina Larsson, Anna Porwit, and Svetlana Bajalica Lagercrantz. Genes, Chromosomes and Cancer, September 2014; 53(9): 750-768. (MGII) http://onlinelibrary.wiley.com/doi/10.1002/gcc.22184/full Development and Validation of Protein Microarray Technology for Simultaneous Inflammatory Mediator Detection in Human Sera. Senthooran Selvarajah, Ola H. Negm, Mohamed R. Hamed, Carolyn Tubby, Ian Todd, Patrick J. Tighe, Tim Harrison, and Lucy C. Fairclough. Mediators of Inflammation, 14 October 2014; 820304, 12pp. (MGII) http://europepmc.org/articles/pmc4213990 Methods for Lung Cancer Classification. Inventor: Gila Lithwick Yanai, and Hila Benjamin.

  • US Patent Application: US 2014/0309123 A1; Publication Date: 16 October 16 2014; (MGII) http://www.freepatentsonline.com/y2014/0309123.html Cancer Diagnosis And Treatment. Inventor: Corrinne Lobe US Patent Application: US 2014/0315732 A1; Publication Date: 23 October 2014; (MGII) http://www.freepatentsonline.com/y2014/0315732.html Gene Expression Signature for Classification of Tissue of Origin of Tumor Samples. Inventors: Ranit Aharonov, Nitzan Rosenfeld, and Shai Rosenwald. US Patent Application: US 2014/0315739 A1; Publication Date: 23 October 2014; (MGII) http://www.freepatentsonline.com/y2014/0315739.html Antigen Array and Diagnostic Uses Thereof. Inventors: Irun R. Cohen, Francisco Javier Quintana, Eytan Domany, Gad Elizur, and Peter H. Hagedorn. US Patent Application: US 2014/0315740 A1; Publ