publications of dr. toshikazu yoshikawa...effect of levamisole on the complement system, jpn j clin...

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Publications of Dr. Toshikazu Yoshikawa Primary research publications Acta Diabetol. : 2 Cell Biol Int. : 1 Immunogenetics. : 1 Jpn J Hyperthermic Oncol. : 2 Acta Haematol. : 3 Chem. Res. Toxicol. : 1 Immunol Lett. : 2 Jpn J Med Ultrasonics. : 1 Acta Neurochir. : 1 Chest. : 3 Immunopharmacol Immunotoxicol. : 4 Jpn J Med. : 2 Acta Physiol. : 1 Circ Shock. : 1 Indian J Gastroenterol. : 1 Jpn J Ophthalmol. : 1 Acta Vitaminol Enzymol. : 1 Circ.Res. : 4 Inflamm Bowel Dis. : 1 Jpn J Pharmacol. : 1 Aliment Pharmacol Ther. : 10 Clin Biochem. : 2 Inflamm Res. : 3 Lab Invest. : 1 Am J Clin Nutr. : 1 Clin Chim Acta : 1 Inflammation. : 1 Lancet : 1 Am J Clin Oncol. : 1 Clin Exp Allergy : 1 Int Arch Allergy Immunol. : 1 Le Journal International de Medicine : 1 Am J Gastroenterol. : 1 Clin Exp Allergy. : 1 Int J Colorectal Dis. : 3 Life Sci. : 5 Am J Obstet Gynecol. : 1 Clin Exp Immunol. : 1 Int J Hyperthermia. : 5 Lipids : 2 Am J Ophthalmol. : 1 Clin Exp Pharmacol Physiol. : 1 Int J Immunopathol Pharmacol. : 2 Liver Int. : 1 Am J Pathol : 2 Clin Exp Pharmacol Physiol. : 1 Int J Mol Med. : 15 Metabolism. : 8 Am J Phisiol. : 1 Clin Exp Metastasis. : 1 Int. F. Hyperthermia : 1 Methods Find Exp Clin Pharmacol. : 1 Am J Physiol Endocrimol Metab. : 1 Clin Immunol. : 1 Int. J. Colorectal Dis : 1 Microcirculation : 1 Am J Physiol Gastrointest Liver Physiol. : 3 Clin J Pain. : 1 Int. J. Hyperthermia : 3 Mod Rheumatol. : 3 Am J Physiol Heart Circ Physiol. : 3 Clin. Exp. Pharmacol. Physiol. : 1 Int. J. Immunopharmacol. : 3 Mol Med. : 1 Am J Physiol. : 1 Clin. Lab. Haem : 2 Int. J. Oncol. : 2 Mol Pharmacol. : 1 Am J Reprod Immunol. : 2 Clinica Chimica Acta. : 1 Intern Med. : 4 Nanomedicine. : 1 Am J Resp Crit Care. : 1 Crit Care Med. : 1 ITE Letters. : 3 Nephrol Dial Transplant. : 2 Am J Respir Crit Care Med. : 1 Curr Med Chem. : 1 J Appl Biochem. : 2 Neurosciences : 1 Anal Biochem. : 1 Diabet Med. : 4 J Appl Toxicol. : 2 Nitric Oxide. : 1 Ann N Y Acad Sci. : 2 Diabetes Care. : 12 J Biol Chem. : 1 Nutrition : 2 Anticancer Res. : 1 Diabetes Res Clin Pract. : 5 J Cell Biochem. : 1 Oncogene : 1 Antioxid Redox Signal. : 4 Dig Dis Sci. : 22 J Clin Apher. : 1 Oncology : 2 Arch Gerontol Geriatr. : 1 Dig Endosc. : 4 J Clin Biochem Nutr. : 35 Pancreas : 1 Arch Intern Med. : 1 Digestion. : 13 J Clin Gastroenterol. : 8 Parasitol Res. : 1 Arch Toxicol. : 1 Endocr J. : 2 J Dermatol Sci. : 1 Pathol Int. : 1 Arthritis Res Ther. : 1 Endoscopy. : 3 J Gastroenterol Hepatol. : 12 Pathophysiology : 3 Arthritis Rheumatism. : 1 Environ Health Perspect. : 1 J Gastroenterol. : 7 Pharmacology : 1 Arzneimittelforschung. : 7 Environ Health Prev Med. : 1 J Health Sci. : 1 Physiol Behav. : 1 Atherosclerosis. : 3 Environ Toxicol Pharmacol. : 1 J Hum Genet. : 1 Physiol Res. : 2 Behavioural Brain Research : 1 Eur J Cardiothorac Surg. : 1 J Interferon Cytokine Res. : 1 Proteins. : 1 Biochem Biophys Acta. : 1 Eur J Nutr. : 1 J Leukoc Biol. : 1 Redox Rep. : 13 Biochem Biophys Res Commun. : 11 Eur J Pharmacol. : 7 J Med Virol. : 1 Res Exp Med. : 3 Biochem Int. : 4 Exp Biol Med. : 8 J Nephrol. : 1 Respir Med. : 1 Biochem Med. : 3 Exp Clin Endocrinol Diabetes. : 1 J Neurochem. : 1 Rheumatol Int. : 1 Biochem Pharmacol. : 1 Exp Therap Med . : 1 J Neurotrauma. : 1 Scand J Gastroenterol. : 5 Biochim Biophys Acta. : 2 Experientia. : 2 J Nutr Biochem. : 2 Sci Rep. : 1 Bioelectrochem. Bioenerg. : 1 Food Chem Toxicol. : 2 J Nutr Sci Vitaminol. : 2 Shock : 3 Biofactors : 10 Food Chem. : 1 J Pharm Pharmacol. : 1 Southern Med J. : 1 Biol Pharm Bull. : 1 Free Radic Biol Med. : 14 J Pharmacol Exp Ther. : 3 Surgery : 1 Biol Res. : 1 Free Radic Res Commun. : 4 J Pharmacol Sci. : 1 Thermal Med. : 1 Biomed Pharmacother. : 1 Free Radic Res. : 3 J Physiol Pharmacol. : 2 Thorax : 3

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Page 1: Publications of Dr. Toshikazu Yoshikawa...Effect of levamisole on the complement system, Jpn J Clin Pharmacol Ther., 11, 1980, 161-170. 14. Enzyme immunoassay of pancreatic oncofetal

Publications of Dr. Toshikazu Yoshikawa

Primary research publications

Acta Diabetol. : 2 Cell Biol Int. : 1 Immunogenetics. : 1 Jpn J Hyperthermic Oncol. : 2

Acta Haematol. : 3 Chem. Res. Toxicol. : 1 Immunol Lett. : 2 Jpn J Med Ultrasonics. : 1

Acta Neurochir. : 1 Chest. : 3 Immunopharmacol Immunotoxicol. : 4 Jpn J Med. : 2

Acta Physiol. : 1 Circ Shock. : 1 Indian J Gastroenterol. : 1 Jpn J Ophthalmol. : 1

Acta Vitaminol Enzymol. : 1 Circ.Res. : 4 Inflamm Bowel Dis. : 1 Jpn J Pharmacol. : 1

Aliment Pharmacol Ther. : 10 Clin Biochem. : 2 Inflamm Res. : 3 Lab Invest. : 1

Am J Clin Nutr. : 1 Clin Chim Acta : 1 Inflammation. : 1 Lancet : 1

Am J Clin Oncol. : 1 Clin Exp Allergy : 1 Int Arch Allergy Immunol. : 1 Le Journal International de Medicine : 1

Am J Gastroenterol. : 1 Clin Exp Allergy. : 1 Int J Colorectal Dis. : 3 Life Sci. : 5

Am J Obstet Gynecol. : 1 Clin Exp Immunol. : 1 Int J Hyperthermia. : 5 Lipids : 2

Am J Ophthalmol. : 1 Clin Exp Pharmacol Physiol.

: 1 Int J Immunopathol Pharmacol.

: 2 Liver Int. : 1

Am J Pathol : 2 Clin Exp Pharmacol Physiol. : 1 Int J Mol Med. : 15 Metabolism. : 8

Am J Phisiol. : 1 Clin Exp Metastasis. : 1 Int. F. Hyperthermia : 1 Methods Find Exp Clin Pharmacol. : 1

Am J Physiol Endocrimol Metab. : 1 Clin Immunol. : 1 Int. J. Colorectal Dis : 1 Microcirculation : 1

Am J Physiol Gastrointest Liver Physiol. : 3 Clin J Pain. : 1 Int. J. Hyperthermia : 3 Mod Rheumatol. : 3

Am J Physiol Heart Circ Physiol. : 3 Clin. Exp. Pharmacol. Physiol. : 1 Int. J. Immunopharmacol. : 3 Mol Med. : 1

Am J Physiol. : 1 Clin. Lab. Haem : 2 Int. J. Oncol. : 2 Mol Pharmacol. : 1

Am J Reprod Immunol. : 2 Clinica Chimica Acta. : 1 Intern Med. : 4 Nanomedicine. : 1

Am J Resp Crit Care. : 1 Crit Care Med. : 1 ITE Letters. : 3 Nephrol Dial Transplant. : 2

Am J Respir Crit Care Med. : 1 Curr Med Chem. : 1 J Appl Biochem. : 2 Neurosciences : 1

Anal Biochem. : 1 Diabet Med. : 4 J Appl Toxicol. : 2 Nitric Oxide. : 1

Ann N Y Acad Sci. : 2 Diabetes Care. : 12 J Biol Chem. : 1 Nutrition : 2

Anticancer Res. : 1 Diabetes Res Clin Pract. : 5 J Cell Biochem. : 1 Oncogene : 1

Antioxid Redox Signal. : 4 Dig Dis Sci. : 22 J Clin Apher. : 1 Oncology : 2

Arch Gerontol Geriatr. : 1 Dig Endosc. : 4 J Clin Biochem Nutr. : 35 Pancreas : 1

Arch Intern Med. : 1 Digestion. : 13 J Clin Gastroenterol. : 8 Parasitol Res. : 1

Arch Toxicol. : 1 Endocr J. : 2 J Dermatol Sci. : 1 Pathol Int. : 1

Arthritis Res Ther. : 1 Endoscopy. : 3 J Gastroenterol Hepatol. : 12 Pathophysiology : 3

Arthritis Rheumatism. : 1 Environ Health Perspect. : 1 J Gastroenterol. : 7 Pharmacology : 1

Arzneimittelforschung. : 7 Environ Health Prev Med. : 1 J Health Sci. : 1 Physiol Behav. : 1

Atherosclerosis. : 3 Environ Toxicol Pharmacol. : 1 J Hum Genet. : 1 Physiol Res. : 2

Behavioural Brain Research : 1 Eur J Cardiothorac Surg. : 1 J Interferon Cytokine Res. : 1 Proteins. : 1

Biochem Biophys Acta. : 1 Eur J Nutr. : 1 J Leukoc Biol. : 1 Redox Rep. : 13

Biochem Biophys Res Commun. : 11 Eur J Pharmacol. : 7 J Med Virol. : 1 Res Exp Med. : 3

Biochem Int. : 4 Exp Biol Med. : 8 J Nephrol. : 1 Respir Med. : 1

Biochem Med. : 3 Exp Clin Endocrinol Diabetes. : 1 J Neurochem. : 1 Rheumatol Int. : 1

Biochem Pharmacol. : 1 Exp Therap Med . : 1 J Neurotrauma. : 1 Scand J Gastroenterol. : 5

Biochim Biophys Acta. : 2 Experientia. : 2 J Nutr Biochem. : 2 Sci Rep. : 1

Bioelectrochem. Bioenerg. : 1 Food Chem Toxicol. : 2 J Nutr Sci Vitaminol. : 2 Shock : 3

Biofactors : 10 Food Chem. : 1 J Pharm Pharmacol. : 1 Southern Med J. : 1

Biol Pharm Bull. : 1 Free Radic Biol Med. : 14 J Pharmacol Exp Ther. : 3 Surgery : 1

Biol Res. : 1 Free Radic Res Commun. : 4 J Pharmacol Sci. : 1 Thermal Med. : 1

Biomed Pharmacother. : 1 Free Radic Res. : 3 J Physiol Pharmacol. : 2 Thorax : 3

Page 2: Publications of Dr. Toshikazu Yoshikawa...Effect of levamisole on the complement system, Jpn J Clin Pharmacol Ther., 11, 1980, 161-170. 14. Enzyme immunoassay of pancreatic oncofetal

1. Phytohemagglutinin skin test in aged individuals. -Preliminary report-, J. Kyoto Pref. Univ. Med., 84,

1975, 77-82.

2. Activation of cellular immunity and complement system in immune-deficient aged subjects by

streptococcal preparation OK-432 (Picibanil), Jpn J Clin Oncol., 7, 1977, 21-26.

3. Hemorrhagic necrosis of the intestinal mucosa associated with disseminated intravascular coagulation.,

Digestion., 17, 1978, 38-45.

4. Complement level in patients with fulminant hepatitis., J. Kyoto Pref. Univ. Med., 87, 1978, 311-318.

5. Experimental protein-losing gastropathy induced by sulfhydryl reagent Dithiothreitol and role of tissue

fibrinolysis., J. Kyoto Pref. Univ. Med., 87, 1978, 319-324.

6. Role of anticoagulants on cold activation of complement., J. Kyoto Pref. Univ. Med., 87, 1978, 373-378.

7. Activation of complement system by streptococcal preparation OK-432(Picibanil) in patients with

malignancy, Jpn J Clin Oncol., 8, 1978, 27-30.

8. Lipid peroxidation and lysosomal enzymes in D-galactosamine hepatitis and its protection by vitamin E.,

Gastroenterol Jpn., 14, 1979, 31-39.

9. Effects of long-term administration of OK-432 (Picibanil), PSK(Krestin) and Levamisole on immune

response in aged subjects without malignancy, Jpn J Clin Oncol., 9, 1979, 209-214.

10. Effect of a streptococcal preparation on the complement system., Jpn J Exp Med., 49, 1979, 343-350.

11. Studies on the pathogenesis of rheumatoid arthritis. 1) Lipid peroxide and lysosomal enzymes in

rheumatoid joints., Jpn J Med., 18, 1979, 199-204.

12. Immunological diagnosis of pancreatic cancer by assaying carcinoembrionic antigen (CEA) in pure

pancreatic juice., Hepatogastroenterology., 27, 1980, 488-494.

13. Effect of levamisole on the complement system, Jpn J Clin Pharmacol Ther., 11, 1980, 161-170.

14. Enzyme immunoassay of pancreatic oncofetal antigens as test for pancreatic cancer., Lancet, 1980, 262-

263.

15. Diagnostic du cancer du pancreas: interet du dosage enzymo-immunologique de l'antigene carcino-fetal

pancreatique, Le Journal International de Medicine, 2 (8), 1980, 715-716.

16. Protective effect of levamisole on carbon tetrachloride-induced lipid peroxidation and hepatotoxicity

, Biomedicine., 35, 1981, 208-211.

17. The protection of coenzyme Q10 against carbon tetrachloride hepatotoxicity., Gastroenterol Jpn., 16,

1981, 281-285.

18. Treatment of ulcerative colitis by the direct administration of an antifibrinolytic agent as an enema.,

Hepatogastroenterology., 28, 1981, 270-273.

Biomedicine. : 1 Front Physiol. : 1 J Surg Oncol. : 2 Thromb Haemost. : 6

Bioorg Med Chem. : 1 Gastroenterol Jpn. : 3 J UOEH. : 1 Thromb Res. : 3

Biosci Biotechnol Biochem. : 3 Gastroenterol Res Pract. : 2 J Diabetes Complications. : 1 Toxicol Appl Pharmacol. : 3

Biosci Rep. : 1 Genes Chromosomes Cancer. : 1 J. Kyoto Pref. Univ. Med. : 8 Toxicology : 3

Blood. : 2 Gut. : 5 JAMA. : 1 Transfus Apher Sci. : 1

Br J Nutr : 1 Haematologia. : 2 Jap J Hypertherm Oncol. : 2 Transplant Proc. : 1

Bull Chem Soc Jpn. : 1 Haemostasis. : 3 Jap J Lung Canc. : 2 Tumor Biol. : 1

Can J Gastroenterol. : 2 Hepatogastroenterology. : 7 Jap J Med. : 1 Vet Hum Toxicol. : 2

Cancer Genet Cytogenet. : 2 Hepatol Res. : 2 Jap J Physiol. : 1 World J Gastroenterol. : 4

Cancer Res. : 4 Hepatology. : 1 Jpn J Cancer Res. : 2 Z med Lab diagn. : 1

Cancer Lett. : 10 Horm Metab Res. : 2 Jpn J Clin Oncol. : 3

Cancer. : 1 Hum Immunol. : 2 Jpn J Clin Pharmacol Ther. : 1

Carcinogenesis. : 1 Hum Reprod. : 2 Jpn J Exp Med. : 1

Page 3: Publications of Dr. Toshikazu Yoshikawa...Effect of levamisole on the complement system, Jpn J Clin Pharmacol Ther., 11, 1980, 161-170. 14. Enzyme immunoassay of pancreatic oncofetal

19. Peritoneal mesothelioma with elevated serum ferritin and β2-microglobulin levels., Jpn J Med., 20, 1981,

114-118.

20. Experimental model of disseminated intravascular coagulation induced by sustained infusion of

endotoxin., Res Exp Med., 179, 1981, 223-228.

21. Azathioprine-induced remission in Weber-Christian disease., Southern Med J., 74, 1981, 234-236.

22. Alpha-tocopherol level in liver diseases., Acta Vitaminol Enzymol., 4, 1982, 311-318.

23. Role of vitamin E in the prevention of hepatocelluar damage : clinical and experimental approach, Ann

N Y Acad Sci, 1982, 198-200.

24. Thiobarbituric acid reactive substances and vitamin E in serum and cerebrospinal fluid from patients

with cerebral apoplexy., Arch Gerontol Geriatr., 1, 1982, 209-218.

25. Cold activation of complement., Arthritis Rheumatism., 25, 1982, 1138-1140.

26. Experimental hypoxia and lipid peroxide in rats., Biochem Med., 27, 1982, 207-213.

27. Effects of vitamin E on D -galactosamine-induced or carbon tetrachloride-induced hepatotoxicity.,

Digestion., 25, 1982, 222-229.

28. The increase of thiobarbituric acid reacting substances in rats with experimental chronic hypoxia.,

Experientia., 38, 1982, 312-313.

29. Immunopotentiators and the protection they give against carbon tetrachloride hepatotoxicity.,

Experientia., 38, 1982, 501-502.

30. Protection by BCG, Levamisole, PS-K, OK-432 and vitamin E against carbon tetrachloride

hepatotoxicity., Hepatogastroenterology., 29, 1982, 240-242.

31. The increase of lipid peroxidation in experimantal hepatitis in rats induced by carbon tetrachloride or

D-galactosamine and its inhibition by pantethine., J Appl Biochem., 4, 1982, 228-233.

32. Complement levels in human tears., Jpn J Ophthalmol., 26, 1982, 229-233.

33. Effect of vitamin E on endotoxin-induced disseminated intravascular coagulation in rats., Thromb

Haemost., 48, 1982, 235-237.

34. Effect of vitamin E on adjuvant arthritis in rats., Biochem Med., 29, 1983, 227-234.

35. Therapeutic effect of a low dosage of human leukocyte interferon on chronic hepatitis B virus infection.,

Digestion., 26, 1983, 205-212.

36. Protective effect of gabexate mesilate against experimental disseminated intravascular coagulation in

rats., Haemostasis., 13, 1983, 262-267.

37. Prevention by methylprednisolone of disseminated intravascular coagulation induced by sustained

infusion of endotoxin in rats., Haemostasis., 13, 1983, 268-273.

38. Effects of FUT-175, a new synthetic protease inhibitor on endotoxin-induced disseminated intravascular

coagulation in rats., Haemostasis., 13, 1983, 374-378.

39. Lipid peroxidation in rat adjuvant arthritis and its inhibition by indomethacin., J Appl Biochem., 5, 1983,

382-387.

40. Lipid peroxidation damage and its protection by vitamin E., J. Kyoto Pref. Univ. Med., 92, 1983, 315-332.

41. Effect of a protein-bound polysaccharide PS-K on the complement system., Res Exp Med., 182, 1983, 85-

94.

42. Effects of ticlopidine and aspirin on endotoxin-induced disseminated intravascular coagulation in rats.,

Thromb Haemost., 49, 1983, 190-192.

43. Lipid peroxidation and experimental disseminated intravascular coagulation in rats induced by

Page 4: Publications of Dr. Toshikazu Yoshikawa...Effect of levamisole on the complement system, Jpn J Clin Pharmacol Ther., 11, 1980, 161-170. 14. Enzyme immunoassay of pancreatic oncofetal

endotoxin., Thromb Haemost., 49, 1983, 214-216.

44. Effects of superoxide dismutase and catalase on disseminated intravascular coagulation in rats., Thromb

Haemost., 50, 1983, 869-872.

45. Effects of very low doses of aspirin on endotoxin-induced disseminated intravascular coagulation in rats.,

Thromb Haemost., 50, 1983, 895.

46. Effect of dipyridamole on experimental disseminated intravascular coagulation in rats., Thromb Res.,

29, 1983, 619-625.

47. The effects of defibrinogenation with batroxobin on endotoxin-induced disseminated intravascular

coagulation in rats., Thromb Res., 31, 1983, 729-735.

48. Effect of low dosage of interferon on natural killer activeity in patients with HBsAg-positive chronic

active hepatitis, Digestion., 30, 1984, 195-199.

49. C3b receptor (CR1) on erythrocytes in various diseases., Immunol Lett., 7, 1984, 325-328.

50. Relation of clinical activity of rheumatoid arthritis to immune complexes, complement components and

anti-immunoglobulins, Rheumatol Int., 4, 1984, 159-163.

51. Endotoxin-induced disseminated intravascular coagulation in vitamin E deficient rats., Toxicol Appl

Pharmacol., 74, 1984, 173-178.

52. The increase of lipid peroxidation in rats adjuvant arthritis and its inhibition by superoxide dismutase,

Biochem Med. , 33, 1985, 320-326.

53. Carbohydrate antigenic determinant (CA19-9) and other tumor markers in gastrointestinal

malignancies., Digestion., 31, 1985, 67-76.

54. Enzyme immuniassay of pancreatic oncofetal antigen(POA)as a marker of pancreatic cancer, Gut., 26,

1985, 450-455.

55. Toxicity of polycyclic aromatic hydrocarbons : I. Effects of phenanthrene, pyrene and their ozonized

products on blood chemistryon rats., Toxicol Appl Pharmacol., 79, 1985, 218-226.

56. Treatment of cancer ascites by intraperitoneal administration of a streptococcal preparation OK-432

with fresh human complement. -Role of complement-derived chemotactic factor to neutrophils., Int. J.

Immunopharmacol., 8, 1986, 715-721.

57. Effects of prostaglandin I 2 and thromboxane A 2 synthetase inhibitor on endotoxin-induced

disseminated intravascular coagulation in rats., J Clin Biochem Nutr., 1, 1986, 31-37.

58. Effects of superoxide dismutase and catalase on endotoxin shock in rats., J Clin Biochem Nutr., 1, 1986,

165-170.

59. Increase in lipid peroxidation in rat gastric mucosal lesions induced by water-immersion restraint stress.,

J Clin Biochem Nutr., 1, 1986, 271-277.

60. Elevated serum CA19-9 levels in poorly controlled diabetic patients., Jap J Med., 25, 1986, 278-280.

61. Immunomodulators and the complement system., Methods Find Exp Clin Pharmacol., 8, 1986, 67-72.

62. Elevated pancreatic oncofetal antigen levels measured by enzyme immunoassay in pure pancreatic juice

of patients with pancreatic cancer., Oncology, 43, 1986, 311-315.

63. Lipopolysaccharide-induced colitis in rabbits., Res Exp Med., 186, 1986, 61-69.

64. Toxicity of polycyclic aromatic hydrocarbons IV. Effects of diphenaldehyde, a major product of ozonized

phenanthrene in rats, Biochem Int., 15, 1987, 139-146.

65. Toxicity of polycyclic aromatic hydrocarbons V. Protective effect of beta-naphthoflavone against

hepatotoxicity induced by diphenaldehyde in rats, Biochem Int., 15, 1987, 147-151.

Page 5: Publications of Dr. Toshikazu Yoshikawa...Effect of levamisole on the complement system, Jpn J Clin Pharmacol Ther., 11, 1980, 161-170. 14. Enzyme immunoassay of pancreatic oncofetal

66. Role of lipid peroxidation and free radical scavengers on endotoxin shock, Bioelectrochem. Bioenerg., 18,

1987, 295-300.

67. Inhibitory effects of FUT-175, a new synthetic protease inhibitor, on intravascular hemolysis by human

serum in mice, Int. J. Immunopharmacol., 9, 1987, 533-537.

68. Role of lipid peroxidation in gastric mucosal lesions induced by burn shock in rats, J Clin Biochem Nutr.,

2, 1987, 163-170.

69. Ulcer formation in rat stomach with diethyldithiocarbamate, J Clin Biochem Nutr., 3, 1987, 189-193.

70. A new percutaneous transhepatic bile drainage tube, J. Kyoto Pref. Univ. Med., 96, 1987, 783-787.

71. Ultrasonic diagnosis of gallstone ileus, J. Kyoto Pref. Univ. Med., 96, 1987, 939-946.

72. Toxicity of polycyclic aromatic hydrocarbons II. Effect of NO2 nitrated phenanthrene and pyren on

blood chemistry in rats., Vet Hum Toxicol., 29, 1987, 25-30.

73. Toxicity of polycyclic aromatic hydrocarbons III. Effect of beta-naphthoflavone pretreatment of

hepatotoxicity of compound producedin ozonation or NO2-nitration of phenanthrene and pyrene in rats.,

Vet Hum Toxicol., 29, 1987, 113-117.

74. Estimation of carbohydrate antigen(CA) 19-9 levels in pure pancreatic juice of patients with pancreatic

cancer, Am J Gastroenterol., 83, 1988, 126-129.

75. Toxicity of polycyclic aromatic hydrocarbons VI. Effects of 1-nitropyrene on serum enzyme levels in rats,

and protection against in by beta-naphthoflavone and dimethyl sulfoxide, Biochem Int., 16, 1988, 929-

934.

76. Toxicity of polycyclic aromatic hydrocarbons VII. Hepatotoxicity of 9-nitrophenanthrene, and

protection against it by beta-naphthoflavone, Biochem Int., 16, 1988, 935-940.

77. Esophageal candidasis, Gastroenterol Jpn., 23, 1988, 363-370.

78. Effects of a protease inhibitor, FUT-175, on pancreatic enzymes released after endoscopic retrograde

cholangio-pancreatography, J Clin Biochem Nutr., 4, 1988, 157-163.

79. Measurement of serum superoxide dismutase activity by electron spin resonance, J Clin Biochem Nutr.,

5, 1988, 1-7.

80. Cellular immunity and tumor growth in vitamin E-sufficient and-deficient mice, J Clin Biochem Nutr.,

5, 1988, 231-239.

81. Diagnostic approach for perforated duodenal ulcer by ultrasonic examination, Jpn J Med Ultrasonics.,

15, 1988, 432-436.

82. Concentration and localization of carbohydrate antigen 19-9 in tissues of pancreatic cancer, Oncology, 45,

1988, 166-171.

83. Role of oxygen-derived free radicals in gastric mucosal injury induced by ischemia or ischemia-

reperfusion in rats, Free Radic Res Commun., 7, 1989, 285-291.

84. Two cases of pancreatic cystadenocarcinoma with elevated CA 19-9 levels in the cystic fluid in comparison

with two cases of pancreatic cystadenoma., Hepatogastroenterology., 36, 1989, 442-445.

85. Effect of zinc-carnosine chelate compound (Z-103) on burn-induced gastric mucosal injury in rats, J Clin

Biochem Nutr., 7, 1989, 107-113.

86. Alterations in thyrotropic hormone, triiodothyronine, and thyroxine in patients postoperative diffuse

purulent peritonitis, J Clin Biochem Nutr., 7, 1989, 243-249.

87. Decreases in left ventricular contractility during endotoxin shock in rabbits, Jap J Physiol., 39, 1989,

963-967.

Page 6: Publications of Dr. Toshikazu Yoshikawa...Effect of levamisole on the complement system, Jpn J Clin Pharmacol Ther., 11, 1980, 161-170. 14. Enzyme immunoassay of pancreatic oncofetal

88. Role of lipid peroxidation and oxygen radicals in compound 48/80-induced gastric mucosal injury in rats,

Scand J Gastroenterol., 24 (Suppl. 162), 1989, 51-54.

89. Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in

rats, Scand J Gastroenterol., 24 (Suppl. 162), 1989, 55-58.

90. Pathogenesis of platelet-activating factor-induced gastric mucosal damage in rats, Scand J

Gastroenterol., 24 (Suppl. 162), 1989, 210-214.

91. A highly sensitive method for determining both Mn-and Cu-Zn superoxide dismutase activities in tissues

and blood clls, Anal Biochem., 187, 1990, 277-280.

92. Role of oxygen radicals in the pathogenesis of gastric mucosal lesions induced by water-immersion

restraint stress and burn in rats., J Clin Biochem Nutr., 8, 1990, 227-234.

93. Role of oxygen-derived free radicals in the pathogenesis of gastric mucosal lesions in rats., J Clin

Gastroenterol., 12, 1990, S65-S71.

94. αANP, immunoreactive insulin, blood glucose and cyclic AMP in normotensive and spontaneously

hypertensive rats subjected to restraint stress, J UOEH., 12, 1990, 283-307.

95. Protective effects of ono-3307, A new synthetic protease inhibitor against experimental disseminated

intravascular coagulation in rats, Thromb Res., 60, 1990, 1-7.

96. Zur Wirkung von Vitamin E auf Uberlebenstrate Und biochemische Parameter wie ICDH, Lactat sowie

ausgewahlte Peptidasen Und Proteasen im Endotoxinschock der Ratte, Z med Lab diagn., 31, 1990, 407-

412.

97. Vitamin E in gastric mucosal injury induced by ischemia-reperfusion, Am J Clin Nutr., 53, 1991, 210-

214.

98. The antioxidant properties of novel zinc-carnosine chelate compound, N-(3-aminopropionyl)-L-

histidinato zinc, Biochem Biophys Acta., 1115, 1991, 15-22.

99. Spin-trapping studies on the reaction of iron complexes with peroxides and the effects of water-soluble

antioxidants, Bull. Chem. Soc. Jpn., 64, 1991, 1447-1453.

100. Elevated tissue concentrations of sialyl Lex-i in cancerous tissues compared with those in noncancerous

tissues of various organs., Cancer., 68, 1991, 111-117.

101. Effect of zinc-carnosine chelate compound (Z-103), a novel antioxidant, on acute gastric mucosal injury

induced by ischemia-reperfusion in rats., Free Radic Res Commun., 14, 1991, 289-296.

102. Combined effects of hepatic arterial embolization using degradable starch microspheres (DSM) in

hyperthemia for liver cancer, Int. J. Hyperthermia, 7, 1991, 231-242.

103. Effects of TJ-35 (shigyaku-san) on gastric mucosal injury induced by ischemia-reperfusion and its

oxygen-derived free radical-scavenging activities, J Clin Biochem Nutr., 10, 1991, 189-196.

104. Investigation into the reactivity between various amino acids and oxygen-derived free radicals by use of

the ESR spin trapping method, J Clin Biochem Nutr., 11, 1991, 161-169.

105. Role of platelet activating foctor (PAF) in superoxide production by human polymorphonuclear

leukocytes, Lipids, 26, 1991, 1227-1230.

106. Learning behavior in chronic vitamin E-deficient and -supplemented rats: radial arm maze learning and

passive avoidance response, Behavioural Brain Research, 51, 1992, 157-164.

107. Augmentative effects of tumor necrosis factor alpha (human, natural type) on polymorphonuclear

leukocyte-derived superoxide generation induced by various stimulants, Int. J. Immunopharmac., 14,

1992, 1391-1398.

Page 7: Publications of Dr. Toshikazu Yoshikawa...Effect of levamisole on the complement system, Jpn J Clin Pharmacol Ther., 11, 1980, 161-170. 14. Enzyme immunoassay of pancreatic oncofetal

108. Role of leukotrienes in gastric mucosal injury induced by ischemia-reperfusion in rats, J Clin

Gastroenterol., 14, 1992, 68-70.

109. Changes in superoxide dismutase activity in the gastric mucosa of peptic ulcer patients, J Clin

Gastroenterol., 14, 1992, 131-134.

110. Effects of a platelet-activating factor antagonist, CV-6209, on gastric mucosal lesions induced by

ischemia-reperfusion, Lipids, 27, 1992, 1058-1060.

111. El mice as a new model for screening the encephalopathic potential of pertussis vaccine, Neurosciences,

18, 1992, s149-s151.

112. Role of oxygen radicals and synergistic effect of superoxide dismutase and catalase on ischemia-

reperfusion injury of the rat pancreas, Transplant Proc., 24, 1992, 797-798.

113. Free radical scavenging activity of the novel anti-ulcer agent rebamipide studied by electron spin

resonance , Arzneimittelforschung., 43, 1993, 363-366.

114. Effect of rebamipide on lipid peroxidation and gastric mucosal injury induced by indometacin in rats,

Arzneimittelforschung., 43, 1993, 1327-1330.

115. The role of active oxygen species and lipid peroxidation in the antitumor effect of hyperthermia, Cancer

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116. Detection of free radicals in the blood of animals using extracorporeal circulation, Free Radic Res

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117. Antioxidant properties of antiulcer kampo medicines, Free Radic Res Commun., 19, 1993, s101-s108.

118. Role of active oxygen, lipid peroxidation and antioxidants in the pathogenesis of gastric mucosal injury

induced by indomethacin in rats, Gut., 34, 1993, 732-737.

119. Effect of sofalcon on gastric mucosal injury induced by ischemia-reperfusion and its antioxidant

properties, J Clin Gastroenterol., 17, 1993, s111-s115.

120. Role of oxygen radicals in indomethacin-induced gastric mucosal microvascular injury in rats, J Clin

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121. Antioxidant therapy in digestive diseases, J Nutr Sci Vitaminol., 39, 1993, s35-s41.

122. Thermochemotherapy for gastrointestinal cancer ?results of a multicenter trial?, Jpn J Hyperthermic

Oncol., 9, 1993, 298-308.

123. Antitumor effect of ischemia-reperfusion injury induced by transient embolization, Cancer Res. , 54,

1994, 5033-5035.

124. Reperfusion injury in gastric mucosa, Ann N Y Acad Sci., 723, 1994, 208-217.

125. Changes in tissue antioxidant enzyme activities and lipid peroxides in endotoxin-induced multiple organ

failure, Circ Shock., 42, 1994, 53-58.

126. Spin trapping of superoxide in aqueous solutions of fresh and aged cigarette smoke, Free Radic Biol Med.,

17, 1994, 361-365.

127. A case-matched control study of intrahepatoarterial chemotherapy in combination with or without

regional hyperthermia for treatment of primary and metastatic hepatic tumors, Int. J. Hyperthermia,

10, 1994, 51-58.

128. Antioxidant properties of bromocriptine, a dopamine agonist , J Neurochem., 62, 1994, 1034-1038.

129. Antioxidative effects of a processed grain food, J Nutr Sci Vitaminol., 40, 1994, 467-477.

130. Effect of rebamipide, a novel anti-ulcer agent, on acute gastric mucosal injury induced by ischemia-

reperfusion in rats, Pathophysiology, 1, 1994, 161-164.

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131. Flow cytometric analysis of nuclear DNA content in the endoscopic biopsy tissues of gastric cancer, Am

J Clin Oncol., 18 (4), 1995, 325-330.

132. Reactive oxidants mediate TNF-α-induced leukocyte adhesion to rat mesenteric venular endothelium,

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133. A novel cancer therapy based on oxygen radicals, Cancer Res. , 55, 1995, 1617-1620.

134. A new gastric ulcer model in rats produced by ferrous iron and ascobic acid injection, Digestion., 56, 1995,

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135. Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats, Dig Dis

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136. Role of neutrophil-mediated inflammation in aspirin-induced gastric mucosal injury, Dig Dis Sci., 40,

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137. Effect of a novel histamine H2 receptor antagonist, IT-066, on acute gastric injury induced by ischemia-

reperfusion in rats, and its antioxidative properties, Eur J Pharmacol. , 294, 1995, 47-54.

138. Hydroxyl radical scavenging by rebamipide and related compounds: Electron paramagnetic resonance

study, Free Radic Biol Med., 18, 1995, 117-123.

139. Simultaneous intraperitoneal administration of OK-432 and serum enhances superoxide generation

from migrated polymorphonuclear leukocytes, with special emphasis on the role of complements,

Immunopharmacol Immunotoxicol., 17, 1995, 265-282.

140. Eight cases of gastric tumors with calcification, Intern Med., 34, 1995, 1038-1042.

141. Role of neutrophil-endothelial cell interactions in gastric mucosal injury induced by aspirin, J Clin

Gastroenterol., 21 (Suppl.1), 1995, s73-s77.

142. Effects of oxygen radical scavengers on the quality of gatric ulcer healing in rats, J Clin Gastroenterol.,

21 (Suppl.1), 1995, s82-s86.

143. Flow-cytometric analysis of nuclear DNA content in tissues of colon cancer using endoscopic biopsy

specimens, J Surg Oncol., 59, 1995, 181-185.

144. Role of lipid peroxidation and neutrophil accumlation in the gastric mucosal injury induced by asprin-

HCl in rats: Effect of roxatidine, a histamine H2 receptor antagonist with antioxidative properties,

Pathophysiology, 2, 1995, 1-8.

145. Local gastric and serum concentrations of rebamipide following oral administration to patients with

chronic gastritis, Arzneimittelforschung., 46, 1996, 698-700.

146. Rebamipide protects against activation of neutrophils by helicobacter pylori, Dig Dis Sci., 41, 1996, 1139-

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147. Candida cholecystitis as an unusual complication of endossopic retrograde cholangiograpby, Endoscopy.,

28, 1996, 790-791.

148. Anti-tomor effects of hyperthermia plus granulocyte colony-stimulating factor, Jpn J Cancer Res., 87,

1996, 862-866.

149. Inhibition of constitutive nitric oxide synthase by benexate, Life Sci., 59, 1996, 953-959.

150. Exogenous xanthine promotes neutrophil adherence to cultured endothelial cells., Am J Phisiol., 273,

1997, G342-G347.

151. Diesel exhaust particles enhance antigen-induced airway inflammation and local cytokine expression in

mice, Am J Respir Crit Care Med., 156, 1997, 36-42.

152. Effect of the histamine H2-receptor antagonist (±)-(E)-1-[2-Hydroxy-2-(4-hydroxyphenyl)ethyl]-3'-[2[[[5-

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methylamino)methyl-2-furyl]methyl]thio]ethyl]-2"-(methylsulfonyl)guanidine on acute gastric mucosal

injury in rats and its free-radical scavenging activities, Arzneimittelforschung., 47, 1997, 845-848.

153. Free radical-scavenging activity of Crassostera gigas extract (JCOE), Biomed Pharmacother., 51, 1997,

328-332.

154. Efficacy of hyperthermia and polyunsaturated fatty acids on experimental carcinoma, Cancer Res. , 57,

1997, 2200-2202.

155. Molecular mechanisms of anoxia/reoxygenation-induced neutrophil adherence to cultured endothelial

cells., Circ.Res., 81, 1997, 992-931.

156. Role of superoxide and nitric oxide in platelet-activating factor-induced acute lung injury, hypotention,

and mortality in rats, Crit Care Med., 25, 1997, 286-292.

157. Effect of Z-103 on TNB-induced colitis in rats, Digestion., 58, 1997, 464-468.

158. Effects of rebamipide, a novel anti-ulcer agent, on gastric mucosal injury induced by platelet-activating

factor in rats, Dig Dis Sci., 42, 1997, 2566-

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159. Bioactivation of lapachol responsible for DNA scission by NADPH-cytochrome P450 reductase, Environ

Toxicol Pharmacol., 3, 1997, 245-250.

160. Effects of aminoguanidineon systemic inflammatory response syndrome induced by platelet activating

factor and by lipopolysaccharide in rats, Eur J Pharmacol., 323, 1997, 107-110.

161. Role of lipid peroxidation and antioxidants in gastric mucosal injury induced by the hypoxanthine-

xanthine oxidase system in rats, Free Radic Biol Med., 23, 1997, 243-250.

162. Generation of reactive oxygen species during interaction of diesel exhaust particle components with

nadph-cytochrome P450 reductase and involvement of the bioactivation in the DNA damage, Free Radic

Biol Med., 22, 1997, 479-487.

163. Intercellular adhesion molecule-1 and CD18 are involved in neutrophil adhesion and its cytotoxicity to

cultuerd sinusoidal endothelial cells in rats, Hepatology., 26, 1997, 658-663.

164. Monochloramine-induced cell growth inhibition and apoptosis in a rat gastric mucosal cell line, J Clin

Gastroenterol., 25 (Supple.1), 1997, S179-S185.

165. Methylprednisolone inhibits neutrophil-endothelial cell interactions induced by interleukin-1β under

flow conditions, Life Sci., 60, 1997, 2341-2347.

166. Quantification of singlet oxygen from hematoporphyrin derivative by electron spin resonance, Life Sci.,

61, 1997, 1953-1959.

167. Interactions of neutrophils and endothelial cells under low flow conditions in vitro, Shock, 8, 1997, 125-

130.

168. α-tocopherol protects against expression of adhesion molecules on neutrophils and endothelial cells,

Biofactors, 7, 1998, 15-19.

169. Oxidative stress in patients with hepatitis, cirrhosis, and hepatoma evaluated by plasma antioxidants.,

Biochem Biophys Res Commun., 247, 1998, 166-170.

170. Rebamipide protects against indomethacin-induced gastric mucosal injury in healthy volunteers in a

double-blind, placebo-controlled study., Dig Dis Sci., 43(9), 1998, 83S-89S.

171. Role of active oxygen species and lipid peroxidation in mepirizole-induced duodenal ulcers in rats, Dig

Dis Sci., 43(8), 1998, 1657-1664.

172. Inhibition of nitric oxide formation and superoxide generation during reduction of LY38583 by neuronal

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nitric oxide synthase, Eur J Pharmacol. , 360, 1998, 213-218.

173. Antioxidant activity of a novel vitamin E derivative, 2-(α-D-Glucopyranosyl) methyl-2,5,7,8-

tetramethylchroman-6-ol, Free Radic Biol Med., 24, 1998, 217-225.

174. Neutrophils, lipid peroxidation, and nitric oxide in gastric reperfusion injury in rats, Free Radic Biol

Med., 24, 1998, 494-502.

175. Diesel exhaust particles enhance airway responsiveness following allergen exposure in mice.,

Immunopharmacol Immunotoxicol., 20(2), 1998, 329-336.

176. Involment of lipid peroxidation in free fatty acid-induced isolated rat pancreatic acinar cell injury,

Pancreas, 17(4), 1998, 383-389.

177. Effect of intermittent hepatic pedicle clamping on free radical generation in the rat liver, Surgery, 129,

1998, 49-56.

178. Oral administration of L-Arginine potentiates allergen-induced airway inflammation and expression of

interleukin-5 in mice, J Pharmacol Exp Ther., 286

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179. Inhalation of diesel exhaust enhances allergen-related eosinophil recruitment and airway

hyperresponsiveness in mice., Toxicol Appl Pharmacol., 150, 1998, 328-337.

180. Calcification in untreated non-hodgkin's lymphoma of the jejunum, Acta Haemotol., 102, 1999, 185-189.

181. Effect of vitamin E in gastric mucosal injury induced by ischaemia-reperfusion in nitric oxide-depleted

rats, Aliment Pharmacol Ther., 13, 1999, 553-559.

182. A novel water-soluble vitamin E derivative protects against experimental colitis in Rats, Antioxid Redox

Signal., 1, 1999, 555-562.

183. Characteristics of the production of active oxygen species from adherent and non-adherent neutrophils,

Biofactors, 9, 1999, 19-26.

184. Molecular mechanisms of neutrophil-endothelial cell adhesion induced by redox imbalance, Circ.Res., 84,

1999, 516-524.

185. Effect of shear stress and a stable prostaglandin I2 analogue on adhesive interactions of colon cancer

cells and endothelial cells, Clin Exp Immunol. , 117, 1999, 430-434.

186. Helicobacter pylori water extract induces interleukin-8 production by gastric epithelial cells, Dig Dis Sci.,

44(2), 1999, 237-242.

187. Pancreatic phospholipase A2 Induced Bacterial Translocation in Rats, Immunopharmacol

Immunotoxicol., 21(4), 1999, 717-726.

188. Effect of zinc on experimental acute pancreatitis in rats, J Clin Biochem Nutr., 26, 1999, 213-225.

189. Role of oxygen radicals in acute gastric mucosal injury induced by taurocholate-serotonin in rats, J Clin

Biochem Nutr., 27, 1999, 69-78.

190. Protective effect of green tea extract against reperfusion injury in rats: antioxidant and anti-

inflammatory properties, J Clin Biochem Nutr., 27, 1999, 89-101.

191. Preoxyl radical-scavenging activity of plasma determined by electron paramagnetic resonance, J Clin

Biochem Nutr., 27, 1999, 103-112.

192. Vitamin E protects against polymorphonuclear leukocyte-dependent adhesion to endothelial cells, J

Leukoc Biol., 65(6), 1999, 757-763.

193. Doubling time of serum CA 19-9 in the clinical course of patients with pancreatic cancer and its

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194. Growth inhibition of A549 human lung adenocarcinoma cells by L-Canavanine is associated with

p21/WAF1 induction, Jpn J Cancer Res., 90, 1999, 69-74.

195. Generation of reactive oxygen species and 8-hydroxy-2'-deoxyguanosine formation from diesel exhaust

particle components in L1210 cells, Jpn J Pharmacol. , 80, 1999, 49-54.

196. Manipulation of the L-arginine-nitric oxide pathway in airway inflammation induced by diesel exhaust

particles in mice, Toxicology, 139, 1999, 19-26.

197. Protective effect of a novel vitamin E derivative on experimental traumatic brain edema in rats -

preliminary study, Acta Neurochir., 76(Suppl), 2000, 343-345.

198. A new mechanism for anti-inflammatory actions of proton pump inhibitors - inhibitory effects on

neutrophil-endothelial cell interactions, Aliment Pharmacol Ther., 14(Suppl. 1), 2000, 74-81.

199. Protective role of intracellular glutathione against nitric oxide-induced necrosis in rat gastric mucosal

cells, Aliment Pharmacol Ther., 14(Suppl. 1), 2000, 145-152.

200. Alpha-tocopherol protects against monocyte Mac-1(CD11b/CD18)expression and Mac-1-dependent

adhesion to endothelial cells induced by oxidized low-density lipoprotein, Biofactors, 11, 2000, 221-233.

201. Inhibition of angiotensin-converting enzyme protects endothelial cell against hypoxia/reoxygenation

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202.

Inhibitory effects of vitamin E on endotherial-dependent adhesive interactions with leukocytes induced

by oxidized low density lipoprotein, Biofactors, 13, 2000, 279-288.

203. T-lympocyte-derived tumor necrosis factor exacerbates anoxia-rexygenation induced neutrophil-

endothelial cell adhesion, Circ.Res., 86, 2000, 205-213.

204. Postanoxic T lymphocyte-endothelial cell interactions induce tumor necrosis factor-α production and

neutrophil adhesion

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205. Effect of vitamin E on aspirin-induced gastric mucosal injury in rats

, Dig Dis Sci., 45(3), 2000, 599-605.

206. Effect of the natural antioxidant 2"-O-glycosylisovitexin on superoxide and hydroxyl radical generation,

Food Chem Toxicol., 38, 2000, 849-852.

207. Induction of aldose reductase in cultured human microvascular endothelial cells by advanced glycation

end products, Free Rad Biol Med., 29(1), 2000, 17-25.

208. Possible paracrine growth of adenocarcinoma of stomach induced by granulocyte colony stimulating

factor produced by squamous cell carcinoma of esophagus, Gut., 46, 2000, 432-434.

209. A case of irinotecan-induced pneumonitis, Jap J Lung Canc., 40, 2000, 219-221.

210. Cytoprotection by metallothionein against gastroduodenal mucosal injury caused by ethanol in mice, Lab

Invest., 80(3), 2000, 371-377.

211. Endothelial cells exposed to anoxia/reoxygenation are hyperadhesive to T-lymphocytes: kinetics and

molecular mechanisms, Microcirculation, 7, 2000, 13-23.

212. Enhancement of nitric oxide genetation by low frequency electromagnetic field, Pathophysiology, 7, 2000,

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213. Primary hepatic burkitt's lymphoma with chronic hepatitis C, Acta Haematol., 105, 2001, 237-240.

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214. Pioglitazone, a specific PPAR-γ ligand, inhibits aspirin-induced gastric mucosal injury in rats, Aliment

Pharmacol Ther., 15, 2001, 865-873.

215. Adult-onset type 1 diabetes with DIDMOAD syndrome-like manifestations, Arch Intern Med., 161, 2001,

767-768.

216. Expression of peroxisome proliferator-activated receptor γ in renal cell carcinoma and growth inhibition

by its agonists, Biochem Biophys Res Commun., 287, 2001, 727-732.

217. Lifestyle, obesity, and insulin resistance, Diabetes Care., 24(3), 2001, 608.

218. Effects of polaprezinc on lipid peroxidation, neutrophil accumulation, and TNF-α expression in rats with

aspirin-induced gastric mucosal injury, Dig Dis Sci., 46(4), 2001, 845-851.

219. Role of P-selection and intercellular adhesion molecule-1 in TNB-induced colitis in rats, Digestion.,

63(suppl 1), 2001, 81-86.

220. The inducible nitric oxide synthase inhibitor ONO-1714 blunts dextran sulfate sodium colitis in mice,

Eur J Pharmacol., 412, 2001, 91-99.

221. Antioxidative effects of fluvastatin and its metabolites against oxidative DNA damage in mammalian

cultured cells, Free Radic Res., 35, 2001, 789-801.

222. Protective effects of fluvastatin againgst reactive oxygen species induced DNA damage and mutagenesis,

Free Radic Res., 34, 2001, 33-44.

223. Treatment of steroid-resistant idiopathic thrombocytopenic purpura in pregnancy with repeated high-

dose intravenous immunoglobulin, Haematologia., 31(3), 2001, 263-265.

224. Role of superoxide and lipid peroxidation in the pathogenesis of dextran sulfate sodium-colitis in mice,

Haematologia., 2(5), 2001, 663-667.

225. Differing effects of two nitric oxide synthase inhibitors on experimental colitis, Hepatogastroenterology.,

48, 2001, 118-122.

226. Detection of 8-hydroxy-2'-deoxyguanosine using an enzyme-linked immunosorbent assay: its application

to cultured cell systems, ITE Letters., 2(2), 2001, 245-250.

227. Effect of retinoic acid on cell proliferation-related gene expression in raji cells induced by 12-O-tetra-

decanoylphorbol-13-acetate., J Clin Biochem Nutr., 30, 2001, 21-31.

228. Inhibition of angiotensin-converting enzyme protects endothelial cells against oxyserol-induces apoptosis,

J Clin Biochem Nutr., 30, 2001, 11-19.

229. Increased Farnesoid X Receptor Expression in Non-small Cell Lung Cancer, Jap J Lung Canc., 41(4),

2001, 293-297.

230. Telomerase activity and expression of telomerase RNA component and catalytic subunits in precancerous

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231. Paraoxonase gene polymorphisms and plasma oxidized low-density lipoprotein level as possible risk

factors for exudative age-related macular degeneration, Am J Ophthalmol., 132, 2001, 191-195.

232. Antituberculous drugs for wegener's granulomatosis, Chest., 120, 2001, 2112.

233. Lipid- lowering agents and artery endothelial function, Chest., 119, 2001, 1979.

234. The cell surface-expressed HSC70-like molecule preferentially reacts with the rat T-cell receptor Vδ6

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235. Unusual myelodysplastic syndrome with the initial presentation mimicking idiopathic thrombocytopenic

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236. Genetic contribution of the interleukin-10 promoter polymorphism in endometriosis susceptibility, Am J

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237. Role of elastase and active oxygen species in gastric mucosal injury induced by aspirin administration

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238. Ubiquitin-proteasome inhibitor enhances tumour necrosis factor-α-induced apoptosis in rat gastric

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239. Murine strain differences in airway inflammation induced by diesel exhaust particles and house dust

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240. Preconditioning with ethanol prevents postischemic leukocyte-endothelial cell adhesive interactions, Am

J Physiol Heart Circ Physiol., 19, 2002, 1000-1005.

241. Diesel Exhaust Particles Enhance Lung Injury Related to Bacterial Endotoxin through Expression of

Proinflammatory Cytokines, Chemokines, and Intercellular Adhesion Molecule-1, Am J Resp Crit Care.,

165, 2002, 1329-1335.

242. α-Phenyl-N-tert-Butylnitrone provides protection from dextran sulfate sodium-induced colitis in mice,

Antioxid Redox Signal., 4(1), 2002, 195-206.

243. Inhibitory effect of a novel water-soluble vitamin E derivative on atherosclerosis in rabbits,

Atherosclerosis., 162, 2002, 111-117.

244. Sensitization of hyperthermic treatment of leukemic cell lines by a synthetic peptide, Bioorg Med Chem.,

10, 2002, 111-115.

245. Recent trends in functional food science and the industry in Japan, Biosci Biotechnol Biochem., 66(10),

2002, 2017-2029.

246. Inhibitory effect of polaprezinc on the inflammatory response to Helicobacter pylori, Can J Gastroenterol.,

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247. Enhancement of lipid peroxidation and of the antitumor effect of hyperthermia upon combination with

oral eicosapentaenoic acid, Cancer Lett., 185, 2002, 139-144.

248. Oxidation of proximal protein sulfhydryls by phenanthraquinone, a component of diesel exhaust

particles, Chem. Res. Toxicol., 15(4), 2002, 483-489.

249. Non-myeloablative haematopoietic stem cell transplantation for severe aplastic anaemia with various

complications, Clin. Lab. Haem, 24, 2002, 303-306.

250. Clinical heterologeneity of patients with adult-onset diabets and GAD autoantibodies, Diabetes Care. ,

25(12), 2002, 2363-2364.

251. Interleukin-6-plymorhism (-634C/G) in the promotor region and the progression of diabetic nephropathy

in Type 2 diabets, Diabet Med, 19, 2002, 1000-1005.

252. Immunomodulatory effects of granulocyte and monocyte adsorption apheresis as a treatment for patients

with ulcerative colitis, Dig Dis Sci., 47(6), 2002, 1334-1341.

253. Intercellular adhesion molecule-1 (ICAM-1) polymorphism is associated with diabetic retinopathy in

Type 2 diabetes mellitus, Diabet Med., 19, 2002, 371-376.

254. α-Tocopherol prevents apoptosis of vascular endothelial cells via a mechanism exceeding that of mere

antioxidation, Eur J Pharmacol., 456, 2002, 29-37.

255. Antioxidant effects of fluvastatin and its metabolites against DNA damage in streptozotocin-treated mice,

Food Chem Toxicol., 40, 2002, 1415-1422.

256. Rosmarinica acid, a major polyphenolic component of perilla frutescens, reduces Lipopolysaccharide

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257. Polymorphisms of interferon-γgene CA-repeat and interleukin-10 promoter region (-592A/C) in Japanese

type I diabets, Hum Immunol., 63, 2002, 121-128.

258. Association of HLA Class I and Class II alleles with susceptibility to endometriosis, Hum Immunol., 63,

2002, 1033-1038.

259. Association of the CYP17 gene and CYP19 gene polymorphisms with risk of endometriosis in Japanese

women, Hum Reprod., 17(4), 2002, 897-902.

260. Anti-inflammatory effect of granulocyte and monocyte adsorption apheresis in a rabbit model of immune

arthritis, Inflammation., 26(4), 2002, 199-205.

261. Urinary 8-Hydroxy-2'-deoxyguanosine excretion in diabetes mellitus, ITE Letters., 3(1), 2002, 92-96.

262. Effect of a novel water-soluble vitamin E derivative, 2-(α-D-Glucopyranosyl) methyl-2,5,7,8-

tetramethylchroman-6-ol, on dextran sulfate sodium-induced colitis in mice, J Clin Biochem Nutr., 31,

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263. Up-Regulation of the Uncoupling Protein Family by Chronic Treatment with a β3-Adrenergic Receptor

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264. Chronic administration with electrolyzed alkaline water inhibits aspirin-induced gastric mucosal injury

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82.

265. An angiotensin-coverting enzyme inhibitor suppresses the expression of vascular cell adhesion molecule-

1 and production of cytokines induced in activated endothelial cells, J Clin Biochem Nutr., 32, 2002, 43-

54.

266. Leukocyte-endothelial cell adhesion molecule 1(LECAM-1) polymorphism is associated with diabetic

nephropathy in type 2 diabetes mellitus, J Diabetes Complications., 16, 2002, 333-337.

267. Mucosal IgA depositon in Henoch-Schonlein purpura with duodenal ulcer, J Gastroenterol Hepatol., 17,

2002, 728-729.

268. ACTH expression in synovium of patients with rheumatoid arthritis and Lewis rats with adjuvant

arthritis, Mod Rheumatol., 12, 2002, 206-212.

269. Aplastic anemia evolving into overt myelodysplastic syndrome/acute myeloid leukemia with

t(3;5)(p25;q31), Mod Rheumatol., 137, 2002, 91-94.

270. A new paradigm for modeling biomacromolecular interactions and complex formation in condensed

phases, Proteins., 48, 2002, 696-732.

271. Edarabone scavenges nitric oxide, Redox Rep., 7(4), 2002, 219-222.

272. Astaxanthin protects β-cells against glucose toxicity in diabetic db/db mice, Redox Rep., 7(5), 2002, 290-

293.

273. Suppression of intestinal ischemia-reperfution injury by a specific peroxisome proliferator-activated

receptor-γ ligand, pioglitazone, in rats, Redox Rep., 7(5), 2002, 294-299.

274. Pioglitazone, PPAR-γ ligand, provides protection from dextran sulfate sodium-induced colitis in mice in

association with inhibition of the NF-κB-cytokine cascade, Redox Rep., 5, 2002, 283-9.

275. A Novel Waterr-Soluble Vitamin E Derivative, 2-(Alpha-D-Glucopyranosyl) Methyl-2, 5, 7, 8-

Tetramethylchroman-6-ol, Protects Against Acute lung Injury and Mortality in Endotoxemic Rats, Shock,

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276. Insulin sensitivity in patients with chronic hepatitis C virus infection, Diabetes Care. , 25(10), 2002,

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277. Preconditioning with ethanol prevents postischemic leukocyte-endothelial cell adhesive interactions, Am

J Physiol Heart Circ Physiol., 283, 2002, H1019-H1030.

278. Discrepancies between clinical and autopsy diagnoses in cases of malignant neoplasm, Chest., 121, 2002,

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279. Lung expression of cytochrome P450 1A1 as a possible biomarker of exposure to diesel exhaust particles,

Arch Toxicol., 76, 2002.2, 146-151.

280. Helicobacter pylori infection potentiates aspirin induced gastric mucosal injury in Mongolian gerbils ,

Gut., 50(5), 2002.5, 594-598.

281. The effect of rebamipide on Helicobacter pylori extract-mediated changes of gene expression in gastric

epithelial cells, Aliment Pharmacol Ther., 18(Suppl. 1), 2003, 63-75.

282. A case of lupus peritonitis and cystitis after ovulation induction therapy, Am J Obstet Gynecol., 189(3),

2003, 888-889.

283. Astaxanthin Limits Exercise-Induced in Skeletal and Cardiac Muscle Damage in Mice, Antioxid Redox

Signal., 5(1), 2003, 139-143.

284. The third-generation bisphosphonate zoledronate synergistically augments the anti-Ph+ leukemia

activity of imatinib mesylate, Blood., 102(6), 2003, 2229-2235.

285. Nephrotic syndrome with crescent formation and massive IgA deposition following allogeneic bone

marrow transplantation for natural killer cell leukemia/lymphoma , Blood., 101(10), 2003, 4219-4221.

286. Tumor initiating activity of Helicobacter pylori water extract on mouse skin carcinogenesis, Cancer Lett.,

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287. Blocking of NF-B activation enhances the tumor necrosis factor α-induced apoptosis of a human gastric

cancer cell line, Cancer Lett., 193, 2003, 177-182.

288. Cancer chemopreventive effects of oral feeding α-tocopherol on ultraviolet light B induced

photocarcinogenesis of hairless mouse, Cancer Lett., 196, 2003, 169-177.

289. Hyperthermia enhances tumor necrosis factor α-induced apoptosis of a human gastric cancer cell line,

Cancer Lett., 201, 2003, 89-96.

290. Variable manifestation in natural killer cell leukaemia, Clin. Lab. Haem, 25, 2003, 239-245.

291. Different effects of constitutive nitric oxide synthase and heme oxygenase on pulmonary or liver

metastasis of colon cancer in mice, Clin Exp Metastasis., 20, 2003, 445-450.

292. Different remodelling against left ventricular overload between diabetic and non-diabetic haemodialysis

patients, Clin Exp Pharmacol Physiol., 30, 2003, 786-792.

293. Association between serum testosterone concentration and carotid atherosclerosis in men with type 2

diabetes, Diabetes Care. , 26(6), 2003, 1869-1873.

294. Increased concentration of pentosidine, an advanced glycation end product, and interleukin-6 in the

vitreous of patients with proliferative diabetic retinopathy, Diabetes Res Clin Pract, 61, 2003, 93-101.

295. Serum extracellular superoxide dismutase in patients with type 2 diabetes, Diabetes Care., 26(4), 2003,

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296. Augmentation of central arterial pressure as a marker of atherosclerosis in patients with type 2 diabets,

Diabetes Res Clin Pract., 59, 2003, 153-161.

297. A novel vitamin E Derivative (TMG) protects against gastric mucosal damage induced by ischemia and

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reperfusion in rats, Dig Dis Sci., 48(1), 2003, 54-58.

298. Effect of 15-deoxy-Δ12,14-prostaglandin J2 on acute lung injury induced by lipopolysaccharide in mice,

Eur J Pharmacol. , 481, 2003, 261-269.

299. The association between end-stage diabetic nephropathy and methylenetetrahydrofolate reductase

genotype with macroangiopathy in type 2 diabets mellitus, Exp Clin Endocrinol Diabetes., 111, 2003,

132-138.

300. Rosmarinic acid inhibits lung injury induced by diesel exhaust particles, Free Rad Biol Med., 34(8), 2003,

1060-1069.

301. Late preconditioning by ethanol is initiated via an oxidant-dependent signaling pathway, Free Radic Biol

Med., 34(3), 2003, 365-376.

302. Fatty Acid Binding Protein Gene 2 Polymorphism Is Not Associated with Diabetic Retinopathy in

Japanese Type 2 Diabetic Patients , Horm Metab Res., 35, 2003, 625-627.

303. Multifocal fibrosclerosis: retroperitoneal fibrosis associated with a suprasellar tumor and

pachymeningitis, Intern Med., 42, 2003, 1006-1010.

304. Roles of cyclooxygenase isoforms in the development of small intestinal injury induced by ischemia-

reperfusion in rats, ITE Letters., 4(2), 2003, 224-229.

305. Possible involvement of TNF-α in left ventricular remodeling in hemodialysis patients, J Nephrol., 16,

2003, 641-649.

306. Hepatitis C virus and atherosclerosis in patients with type 2 diabetes, JAMA., 289(10), 2003, 1245-1246.

307. Enhanced instestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha

deficient mice, J Gastroenterol Hepatol., 18, 2003, 560-569.

308. Enhancement of the antitumor effect of hyperthermia by buthionine sulphoximine, Jpn J Hyperthermic

Oncol., 19(1), 2003, 23-29.

309. Non-steroidal anti-inflammatory drug, nabumetone, prevents indometacin-induced gastric damage via

inhibition of neutrophil functions, J Pharm Pharmacol., 55, 2003, 229-237.

310. The high incidence of left atrial appendage thrombosis in patients on maintenance haemodialysis,

Nephrol Dial Transplant., 18, 2003, 2339-2347.

311. An AT1-Receptor antagonist and an angiotensin-converting enzyme inhibitor protect against hypoxia-

induced apoptosis in human aortic endothelial cells through upregulation of endothelial cell nitric oxide

synthase activity , Shock, 19 (6), 2003, 547-552.

312. Clinical and genetic heterogeneity of latent autoimmune diabetes in adults, Diabetes Care. , 26(7), 2003,

2223.

313. Enhancement of acute lung injury related to bacterial endotoxin by components of diesel exhaust

particles, Thorax, 58(7), 2003, 605-612.

314. Glycyrrhizin and serum testosterone concentrations in male patients with type 2 diabets, Diabetes Care.,

26(10), 2003, 2962.

315. Association between elevated testosterone and development of microalbuminuria during puberty in

female subjects with type 1 diabets, Diabetes Care., 26(10), 2003, 2967.

316. Effects of 15-deoxy-Δ12, 14-prostaglandin J2 on the cyclooxygenase-2 expression in the murine lung in

the presence of lipopolysaccharide, Arzneimittelforschung., 54(11), 2004, 711-714.

317. Inhibitory effect of pioglitazone on expression of adhesion molecules on neutrophils and endothelial cells,

Biofactors, 20, 2004, 37-47.

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318. Prevention of diabetic nephropathy by treatment with astaxanthin in diabetic db/db mice, Biofactors, 20,

2004, 49-59.

319. Anti-inflammatory and anti-allergic effect of rosmarinic acid (RA); inhibition of seasonal allergic

rhinoconjunctivitis (SAR) and its mechanism., Biofactors, 21, 2004, 127-131.

320. Inhibitory effects of red wine extracts on endothelial-dependent adhesive interactions with monocytes

induced by oxysterols., Biol Res., 37, 2004, 231-238.

321. Effects of Helicobacter pylori water extract on expression of endothelial adhesion molecules, Can J

Gastroenterol., 18 (6), 2004, 387-391.

322. Anoxia/reoxygenation down-regulates the expression of E-cadherin in human colon cancer cell lines,

Cancer Lett., 211, 2004, 79-87.

323. Rosmarinica acid inhibits epidermal inflammatory responses: anticarcinogenic effect of Perilla

frutescens extract in the murine two-stage skin model, Carcinogenesis., 25 (4), 2004, 549-557.

324. Rosmarinica acid in perilla extract inhibits allergic inflammation induced by mite allergen, in a mouse

model, Clin Exp Allergy, 34, 2004, 971-977.

325. Enzyme-linked immunosorbent assay for circulating human resistin: resistin concentrations in normal

subjects and patients with type 2 diabetes, Clinica Chimica Acta., 339, 2004, 57-63.

326. A novel water-soluble vitamin E derivative prevents acute lunb injury by bacterial endotoxin, Clin Exp

Pharmacol Physiol. , 31, 2004, 226-230.

327. Idiopathic sudden hearing loss in patients with type 2 diabetes, Diabetes Res Clin Pract, 63, 2004, 205-

211.

328. Protective effects of preischemic treatment with pioglitazone, a peroxisome proliferator-activated

receptor-γ ligand, on lung ischemia-reperfusion injury in rats, Eur J Cardiothorac Surg., 25, 2004, 530-

536.

329. Extract of Perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits

seasonal allergic rhinoconjunctivitis in humans, Exp Biol Med., 229, 2004, 247-254.

330. Nitrogen dioxide air pollution near ambient levels is an atherogenic risk primarily in obese subjects: a

brief communication, Exp Biol Med., 229, 2004, 361-364.

331. Complementary DNA Micriarray Anakysis in Acute Lung Lnjury Induced by Lipopolysaccharide and

Diesel Exhaust Particles, Exp Biol Med., 229, 2004, 1081-1087.

332. CYP3A induction aggravates endotoxemic liver injury via reactive oxygen species in male rats, Free Rad

Biol Med., 37 (5), 2004, 703-712.

333. Oxidative stress and delayed-onset muscle damage after expercise, Free Radic Biol Med., 37(4), 2004,

480-487.

334. An endogenous metabolite of dopamine, 3,4-dihydroxyphenylethanol, acts as a unique cytoprotective

agent against oxidative stress-induced injury, Free Radic Biol Med., 36(5), 2004, 555-564.

335. Effects of growths hormone (GH) on mRNA levels of uncoupling proteins 1, 2, and 3 in brown and white

adipose tissues and skeletal muscle in obse mice, Horm Metab Res., 36, 2004, 607-613.

336. Interferon-γ gene dinucleotide (CA) repeat and interleukin-4 promoter region (-590C/T) polymorphisms

in Japanese patients with endometriosis, Hum Reprod., 19 (8), 2004, 1765-1769.

337. An orally active matrix metalloproteinase inhibitor, ONO-4817, reduces dextran sulfate sodium-induced

colitis in mice, Inflamm Res., 53, 2004, 462-468.

338. Edaravone, a newly developed radical scavenger, protects aainst ischemia-reperfusion injury of the small

Page 18: Publications of Dr. Toshikazu Yoshikawa...Effect of levamisole on the complement system, Jpn J Clin Pharmacol Ther., 11, 1980, 161-170. 14. Enzyme immunoassay of pancreatic oncofetal

intestine in rats, Int J Mol Med., 13, 2004, 105-109.

339. Reduced intestinal inflammation induced by dextran sodium sulfate in interleukin-6-deficient mice, Int

J Mol Med., 14, 2004, 191-196.

340. Mouse strain differences in eosinophilic airway-inflammation caused by intratracheal instillation of mite

allergen and diesel exhaust particles, J Appl Toxicol., 24, 2004, 69-76.

341. Components of diesel exhaust particles differently affect lung expression of cyclooxygenase-2 related to

bacterial endotoxin, J Appl Toxicol., 24(6), 2004, 415-418.

342. Hyperthermia enhances free radical-dependent cytotoxicity of gamma-linolenic acid on AH109a rat

hepatocellular carcinoma cells, Jap J Hypertherm Oncol., 20(1), 2004, 15-22.

343. Tumor necrosis factor-α-induced cytokine-induced neutrophil chemoattractant-1 (CINC-1) production by

rat gastric epithelial cells: role of reactive oxygen species and nuclear factor-κB, J Pharmacol Exp Ther.,

309 (2), 2004, 670-676.

344. Effect of exercise on hepatic gene expression in rats: a microarray analysis, Life Sci., 75, 2004, 3117-3128.

345. A novel potent inhibitor of inducible nitric oxide inhibitor, ONO-1714, reduces intestinal ischemia-

reperfusion in jury in rats, Nitric Oxide., 10, 2004, 170-177.

346. Rotenone, a mitochondrial electron transport inhibitor, ameliorates ischemia-reperfusion-induced

intestinal mucosal damage in rats., Redox Rep., 9, 2004, 313-316.

347. Gene expression analysis following hypoxia-reoxygenation in rat gastric epithelial cells using a high-

density oligonucleotide array., Redox Rep., 9, 2004, 337-342.

348. Singlet oxygen quenching activity of human serum, Redox Rep., 9, 2004, 325-330.

349. Laser capture microdissection/GeneChip analysis of gene expression in glomerular cells in diabetic db/db

mice, Redox Rep., 9, 2004, 307-312.

350. 7-Ketocholesterol enhances the expression of adhesion molecules on human aortic endothelial cells by

increasing the production of reactive oxygen species, Redox Rep., 9, 2004, 370-375.

351. The inhibitory effect of alacepril, an angiotensin-converting enzyme inhibitor, on endothelial

inflammatory response induced by oxysterol and TNF-alpha., Redox Rep., 9, 2004, 354-359.

352. Short-term exposure of high glucose concentration induces generation of reactive oxygen species in

endothelial cells: implucation for the oxidative stress associated with postrandial hyperglycemia, Redox

Rep., 9 (2), 2004, 111-116.

353. A PPAR-gamma ligand, 15-deoxy-Delta12, 14-prostaglandin J(2), inhibited gastric mucosal injury

induced by ischemia-reperfusion in rats, Redox Rep., 9, 2004, 376-381.

354. Interleukin-8 expression in the esophageal mucosa of patients with gastroesophageal reflux disease,

Scand J Gastroenterol., 9, 2004, 816-822.

355. Protective role of metallothionein in acute lung injury induced by bacterial endotoxin, Thorax, 59, 2004,

1057-1062.

356. Genetic contribution of tumor necrosis factor (TNF)-alpha gene promoter (-1031, -863 and -857) and TNF

receptor 2 gene polymorphisms in endometriosis susceptibility, Thorax, 59, 2004, 1057-1062.

357. Protective role of interleukin-6 in coagulatory and hemostatic disturbance induced by lipopolysaccharide

in mice, Thromb Haemost., 91, 2004, 1194-1201.

358. Lansoprazole ameliorates intestinal mucosal damage induced by ischemia-reperfusion in rats, World J

Gastroenterol., 10(19), 2004, 2814-2817.

359. Association Between Urinary Albumin Excretion and Serum Dehydroepiandrosterone Sulfate

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Concentrations in Women With Type 2 Diabetes, Diabetes Care. , 27(12), 2004, 2893-2897.

360. Increased serum resistin levels in patients with type 2 diabetes are not linked with markers of insulin

resistance and adiposity, Acta Diabetol., 42, 2005, 104-109.

361. Daily profile of plasma %CoQ10 level, a biomarker of oxidative stress, in patients with diabetes

manifesting postprandial hyperglycaemia, Acta Diabetol., 42, 2005, 179-181.

362. Copper chelation with tetrathiomolybdate suppresses adjuvant-induced arthritis and inflammation-

associated cachexia in rats, Arthritis Res Ther., 7, 2005, R1174-R1182.

363. Effects of 15-Deoxy-△12,14-prostaglandin J2 on Nuclear Localization of GATA-3 in the Murine Lung in

the Presence of Lipopolysaccharide , Arzneimittelforschung., 55(3), 2005, 167-171.

364. Effects of 15-deoxy-Δ12, 14-prostaglandin J2 on nuclear localization of GATA-3 in the murine lung in the

presence of lipopolysaccharide, Arzneimittelforschung., 55

(3), 2005, 167-171.

365. Serum dehydroepiandrosterone sulfate concentration and carotid atherosclerosis in men with type 2

diabetes, Atherosclerosis., 181, 2005, 339-344.

366. Tocotrienols reduce 25-hydroxycholestrol-induced monocyte-endothelial cell interaction by inhibiying the

surface expression of adhesion molecules, Atherosclerosis., 180, 2005, 19-25.

367. Reduction of diabetes-induced renal oxidative stress by a cantaloupe melon extract/gliadin

biopolymers,oxykine,mice, Biofactors, 23, 2005, 85-95.

368. Sonoporation using microbubble BR14 promotes pDNA/siRNA transduction tu murine heart, Biochem

Biophys Res Commun., 336, 2005, 118-127.

369. Synergic action of insulin and genistein on Na+/K+/2Cl Cotransporter in renal epithelium, Biochem

Biophys Res Commun., 332, 2005, 1042-1052.

370. Gene expression profile of isolated rat adipocytes treated with anthocyanins, Biochim Biophys Acta.,

1733, 2005, 137-147.

371. Interleukin-10 plasmid DNA inhibits subcutaneous tumor growth of Colon26 adenocarcinoma in mice,

Cancer Lett., 218, 2005, 171-179.

372. Tumor suppressive effects of tocotrienol in vivo and in vitro , Cancer Lett., 229, 2005, 181-191.

373. The radical scavenger edaravone enhances the anti-tumor effect of CPT-11 in murine colon cancer by

increasing apoptosis via inhibition of NF-κB, Cancer Lett., 229, 2005, 223-233.

374. Effects of 15-deoxy-Δ12, 14-prostaglandin J2 on the expression of toll-like receptor 4 and 2 in the murine

lung in the presence of lipopolysaccharide, Clin. Exp. Pharmacol. Physiol., 32(3), 2005, 230-232.

375. Thr54 allele of the FABP2 gene affects resting metabolic rate and visceral obesity+, Diabetes Res Clin

Pract, 67, 2005, 36-42.

376. Association between alcohol consumption and serum dehydroepiandrosterone sulphate concentration in

men with Type2 diabetes: a link to decreased cardiovascular risk, Diabet Med, 22, 2005, 1446-1450.

377. A Comparative Study on Endoscopic Ulcer Healing of Omeprazole Versus Rabeprazole with Respect to

CYP2C19 Genotypic Differences, Dig Dis Sci., 50 (9), 2005, 1625-1631.

378. Efficacy of Glimepiride in Patients with Poorly Contorolled Insulin-treated Type 2 Dibetes Mellitus,

Endocr J., 52(5), 2005, 563-569.

379. Absorption, metabolism, degradation and urinary excretion of rosmarinic acid after intake of Perilla

frutescens extract in humans., Eur J Nutr., 44, 2005, 1-9.

380. Role of metallothionein in antigen-related airway inflammation, Exp Biol Med., 230(1), 2005, 281-287.

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381. Role of metallothionein in antigen-related airway inflammation, Exp Biol Med., 230, 2005, 75-81.

382. Protective role of interleukin-6 in coagulatory and hemostatic disturbance induced by lipopolysaccharide

in mice, Exp Biol Med., 230, 2005, 281-287.

383. Clinical and genetic characteristics of diabetic patients with high-titer(>10,000U/ml) of antibodies tu

glutamic acid decarboxylase, Immunol Lett., 99, 2005, 180-185.

384. Cytoprotection by interleukin-6 against liver injury induced by lipopolysaccharide, Int J Mol Med., 15

(2), 2005, 221-224.

385. Effects of volatile constituents of a rosemary extract on allergic airway inflammation related to house

dust mite allergen in mice, Int J Mol Med., 16, 2005, 315-319.

386. Antioxidative role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide, Int J

Mol Med., 16, 2005, 1029-1033.

387. Heme oxygenase-1(Hsp32) is involved in the protection of small intestine by whole body mild

hyperthemia from ischemia/reperfusion injury in rat, Int J Hyperthermia., 21(7), 2005, 603-614.

388. Relation between polymorphisms G1704T and G82S of rage gene and diabetic retinopathy in Japanese

type 2 diabetic patient

s, Intern Med., 44, 2005, 417-421.

389. Cytokine-induced neutrophil accumulation in the pathogenesis of acute reflux esophagitis in rats, Int J

Mol Med., 16, 2005, 70-77.

390. A novel water-soluble vitamin E derivative protects against aspirin-induced gastric mucosal injury in

rats, Int J Mol Med., 16, 2005, 1035-1040.

391. Imidapril,an Angiotensin-Converting Enzyme Inhibitor,Reduces Diabetes-Induced Renal Oxidative

Damage in Mice, J Clin Biochem Nutr., 37, 2005, 29-37.

392. The Effect of Combination Terapy Using Regional Hyperthermia and Transarterial Chemoembolization

for the Treatment of Large Hepatocellular Carcinomas, Jap J Hypertherm Oncol., 21(1), 2005, 13-18.

393. In Vitro and In Vivo Evaluation of Adacolumn Cytapheresis in Healthy Subjects, J Clin Apher., 20, 2005,

72-80.

394. Tea Catechins with a Galloyl Moiety Reduce Body Weight and Fat, J Health Sci., 51(2), 2005, 161-171.

395. Malnutrition and disease progression in patients with rheumatoid arthritis, Mod Rheumatol., 15, 2005,

104-107.

396. Urinary trypsin inhibitor protects against systemic inflammation induced by lipopolysaccharide, Mol

Pharmacol., 67, 2005, 673-680.

397. Prevention by Rebamipide of Acute Reflux Esophagitis in Rats, Dig Dis Sci., 50, 2005, S97-S103.

398. Rebamipide, a Gastroprotective Drug, Inhibits Indomethacin-Induces Apoptpsis in Cultured Rat

Gastric Mucosal Cells: Association with the Inhibition of Growth Arrest and DNA Damage-Induced 45α

Expression, Dig Dis Sci., 50, 2005, S104-S112.

399. Global Analysis of Gene Expression in Gastiric Ischemia-Reperfusion: A Future Therapeutic Direction

for Mucosal Protective Drugs, Dig Dis Sci., 50, 2005, S45-S55.

400. Increased intestinal luminal carbon monoxide gas in patients with ulcerative colitis, Aliment Pharmacol

Ther., 2, 2006, 233-238.

401. Gene expression clusters of a lipopolysaccharide-stimulated pathway in peripheral blood monocytes of

Japanese patients with Crohn’s disease, Aliment Pharmacol Ther., 2, 2006, 256-265.

402. Molecular mechanisms involved in interleukin-8 production by normal human oesophageal epothelial

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cells, Aliment Pharmacol Ther., 2, 2006, 219-226.

403. Synergistic effect of interleukin-6 promoter(IL6-634C/G) and intercellular adhesion molecule-1(ICAM-1

469K/E) gene polymorphisms on the risk of endometriosis in Japanese Women, Am J Reprod Immunol.,

56, 2006, 267-274.

404. Role of oxygen-derived free radicals in Helicobacter pylori water extract-induced mouse skin

carcinogenesis, Biofactors, 28, 2006, 1-7.

405. Microarray profiling of gene expression in human adipocytes in response to anthocyanins, Biochem

Pharmacol., 71, 2006, 1184-1197.

406. Relationship between insulin resistance and inflammatory markers and anti-inflammatory effect of

losartan in patients with type 2 diabetes and hypertension, Clin Chim Acta, 2006.

407. Components of diesel exhaust particles differentially affect Th1/Th2 response in a murine model of

allergic airway inflammation, Clin Exp Allergy., 36, 2006, 386-395.

408. Effect of a novel water-soluble vitamin E derivateve as a cure for TNBS-induced colitis in rats, Int J Mol

Med., 17, 2006, 497-502.

409. Lansoprazole, a proton pump inhibitor, redudces the severity of infomethacin-induced rat enteritis, Int

J Mol Med., 17, 2006, 89-93.

410. Rosuvastatin, a new HMG-CoA reductase inhibitor,reduces the colonic inflammatory response in dextran

sulfate sodium-induced colitis in mice, Int J Mol Med., 17, 2006, 997-1004.

411. Microarray profiling of gene expression patterns in glomerular cell of astaxanthin-treated diabetic mice:

A nutrigenomic approach, Int J Mol Med., 18, 2006, 685-695.

412. Inflammatory response of esophageal epithelium in combined-type esophagitis in rats: A transcriptome

analysis, Int J Mol Med., 18, 2006, 821-828.

413. Role of pancreatic trypsin in chronic esophagitis induced by gastroduodenal reflux in rats, J

Gastroenterol., 41, 2006, 198-208.

414. Alkoxyl Radical-Scavenging Activity of Edaravone in Patients with Traumatic Brain Injury, J

Neurotrauma., 23(11), 2006, 1591-1599.

415. Partially hydrolyzed guar gum down-regulates colonic inflammatory response in dextran sulfate sodium-

induced colitis in mice, J Nutr Biochem., 17, 2006, 402-409.

416. Effect of Atorvastatin on in Vitro Expression of Resistin in Adipocytes and Monocytes/Macrophages and

Effect of Atorvastatin Treatment on Serum Resistin Levels in Patients with Type 2 Diabetes,

Pharmacology, 76, 2006, 34-39.

417. Differential regulation of intracellular redox state by extracellular matrix proteins in glomerular

mesangial cell: potential role in diabetic nephropathy, Redox Rep., 11(5), 2006, 223-230.

418. A novel potent inhivitor of inducible nitric oxide synthase, ONO-1714,reduces hyperoxic lung injury in

mice, Respir Med., 2006.

419. Anti-tryptase treatment using nafamostat mesilate has a therapeutic effect on experimental colitis,

Scand J Gastroenterol., 41, 2006, 944-953.

420. Methylparaben potentiates UV-induced damage of skin keratinocytes, Toxicology, 227, 2006, 62-72.

421. Integrin-Linked kinase acts as a pro-survival factor against high glucose-associated osmotic stress in

human mesangial cells, Nephrol Dial Transplant., 21, 2006, 1786-1793.

422. Di-(2-ethylhexyl)Phthalate Enhances Atopic Dermatitis-Like Skin Lesions in Mice, Environ Health

Perspect., 114(8), 2006, 1266-1269.

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423. Role of calcitonin gene-related peptide in the postischemic anti-inflammatory effect of antecedent

ethhanol ingestion, Am J Physiol Heart Circ Physiol., 290, 2006, 531-537.

424. Serum anti-ribosomal P antibody reflected the activity of neuropsychiatric syndromes in systemic lupus

erythematosus: Report of 2 cases, J. Kyoto Pref. Univ. Med., 115(2), 2006, 65-73.

425. Low serum dehydroepiandrosterone sulfate concentration is a predictor for deterioration of urinary

albumin excretion in male patients with type 2 diabetes, Diabetes Res Clin Pract, 73, 2006, 47-50.

426. Molecular mechanisms involved in anti-inflammatory effects of proton pump inhibitors, Inflamm Res.,

55, 2006, 476-480.

427. Gene Expression Profiles on Hypoxia and Reoxygenation in Rat Gastric Epithelial Cells: A High-Density

DNA Microarray Analysis, Digestion., 73, 2006, 89-100.

428. CV-11974, angiotensin Ⅱ typeⅠreceptor antagonist,protects against ischemia-reperfusion injury of the

small intestine in rats, Eur J Pharmacol. , 535, 2006, 283-290.

429. Advanced Glycation Endproducts Act as An Initiator of Skin Tumors in Mice, J Clin Biochem Nutr., 38,

2006, 176-179.

430. Contrasting Genome-Wide Distribution of 8-Hydroxyguanine and Acrolein-Modified Adenine during

oxidative Stress-Induced Renal Carcinogenesis, Am J Pathol, 169(4), 2006, 1328-1342.

431. Administration of FR167653,a New Anti-Inflammatory Compound,Inhibits Aspirin-Induced Gastric

Mucosal Injury in Rats, J Clin Biochem Nutr., 39, 2006, 69-74.

432. Role of the thrombin/protease-activated receptor 1 pathway in intestinal ischemia-reperfusion injury in

rats, Am J Physiol Gastrointest Liver Physiol. , 292, 2007, G678-G683.

433. Does Edaravone(MCI-186)Act as an Antioxidant and a Neuroprotector in Experimental Traumatic Brain

Injury?, Antioxid Redox Signal., 9(2), 2007, 281-287.

434. Effects of nanoparticles on lung physiology in the presence or absence of antigen, Biochem Biophys Res

Commun., 20(4), 2007, 737-744.

435. Effects of Black Currant Polysaccharide for Japanese cedar pollinosis Effects of Popysaccharide Derived

from Black Currant in Relieving Clinical Symptoms of Japanese Cedar Pollinosis. A randomized Double

Blind, Placebo Controlled Trial, Biosci Biotechnol Biochem., 2007, 3019-3025.

436. Abnormal expression of ENaC and SGK1 mRNA induced by dietary sodium in Dahl salt-sensitively

hypertensive ras, Cell Biol Int., 31, 2007, 1288-1291.

437. Relationship of serum brain-derived neurotrophic factor level with other markers of disease severity in

patients with atopic dermatitis, Clin Immunol., 122, 2007, 181-186.

438. Association Between Urinary Albumin Excretion and Serum Dehydroepiandrosterone Sulfate

Concentrations in Women With Type 2 Diabetes, Diabetes Care. , 30(7), 2007, 1886-1888.

439. Association Between Urinary Albumin Excretion and Plasma 5-Hydroxyindole-3-Acetic Acid

Concentrations in Men With Type 2 Diabetes, Diabetes Care. , 30(10), 2007, 2649-2651.

440. Metabolic syndrome is not associated with markers of subclinical atherosclerosis,serum adiponedctin

and endogenous androgen concentrations in Japanese men with Type 2 diabetes, Diabet Med, 24, 2007,

864-871.

441. Helicobacter pylori activates gastric epithelial cells to produce interleukin-8 via protease-activated

receptor 2, Digestion., 76, 2007, 248-255.

442. Low serum testosterone concentration in middle-aged men with type 2 diabetes, Endocr J., 54(6), 2007,

871-877.

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443. Role of Interleukin-6 in Toll-Like Receptor 4 and 2 Expressions Induced by Lipopolysaccharide in the

Lung , Immunopharmacol Immunotoxicol., 29, 2007, 63-68.

444. Antitumor effect of whole body hyperthermia with α-galactosylceramide in a subcutaneous tumor model

of colon cancer, Int J Hyperthermia., 23(7), 2007, 591-598.

445. Candida soluble cell wall β-D-glucan induces lung inflammation in mice, Int J Immunopathol Pharmacol.,

20(3), 2007, 499-508.

446. Interleukin-8 production via protease-activated receptor 2 in human esophageal epithelial cells, Int J

Mol Med., 19, 2007, 335-340.

447. SPNs in the KCNJ11-ABCC8 gene locus are associated with type 2 diabetes and blood pressure levels in

the japanese population. , J Hum Genet., 2007, 781-93.

448. Inhibitory effect of fermented milk on delayed-onset muscle damage after execise, J Nutr Biochem., 18,

2007, 140-145.

449. Relationship between low serum endogenous androgen concentrations and arterial stiffness in men with

type 2 diabetes mellitus, Metabolism., 56, 2007, 1167-1173.

450. Association between serum testosterone concentration and collagen degradation fragments in men with

type 2 diabetes mellitus, Metabolism., 56, 2007, 1228-1232.

451. Gene Expression Analysis of Murine Lungs Following Pulmonry Exposure to Asian Sand Dust Particles,

Exp Biol Med., 2007, 1109-1118.

452. Chronic oxidative stress causes amplification and overexpresson of ptprz1 protein tyrosine phosphatase

to activate β-catenin pathway, Am J Pathol, 171(6), 2007, 1978-1988.

453. Effects of inhaled nanoparticles on acute lunf injury induced by lippolysaccharide in mice, Toxicology,

238, 2007, 99-110.

454. Whole body hyperthermia improves obesity-induced insulin resistanice in diabetic mice, Int J

Hyperthermia., 23(3), 2007, 259-265.

455. Hyperthermia attenuates TNF-alpha-induced up regulation of endothelial cell adhesion molecules in

human arterial endothelial cells, Int J Hyperthermia., 23(3), 2007, 217-224.

456. Arterial stiffness acutely decreases after whole-body vibration in humans, Acta Physiol., 194, 2008, 189-

194.

457. Astaxanthin improves muscle lipid metabolism in exercise via inhibitory effect of oxidative CPT I

modification, Biochem Biophys Res Commun., 366, 2008, 892-897.

458. Size effects of nanomaterials on lung inflammation and coagulatory disturbance, Biochem Biophys Res

Commun., 21(1), 2008, 197-2006.

459. Serum prostate-specific antigen levels in men with type 2 diabetes, Diabetes Care. , 31, 2008, 930-931.

460. Helicobacter pylori isolated from a patient wit Menetrier’s disease increases hepatocyte growth factor

mRNA expression in gastric fibroblasts: domparison with Helicobacter pylori isolated from other gastric

diseases, Dig Dis Sci., 53, 2008, 1785-1791.

461. Effects of a sequential combination of hyperthermia and gemcitabine in the treatment of adanced

unresectable pancreatic cancer: a retrospective study, Dig Dis Sci., 24(4), 2008, 131-139.

462. Hepatobiliary sarcoidosis: typical appearance in laparoscopy, Dig Endosc., 20, 2008, 162-165.

463. Expression of inducible nitric oxide synthase and nitric oxide-modified in Helicobacter pylori-associated

atrophic gastric mucosa, J Gastroenterol Hepatol., 23, 2008, S250-S257.

464. Dextran sulfate sodium-induced acute colonic inflammation in angiotensin II type 1a receptor deficient

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mice, Inflamm Res., 57, 2008, 84-91.

465. Antioxidative role of interleukin-6 in septic lung injury in mice, Int J Immunopathol Pharmacol., 21(3),

2008, 501-507.

466. Randomized controlled trial of two forms of self-management group education in Japanese people with

impaired glucose, J Clin Biochem Nutr., 43(2), 2008, 82-87.

467. Intervention with Delivery of Diabetic Meals Improves Glycemic Control in Patients with Type 2

Diabetes Mellitus , J Clin Biochem Nutr., 42, 2008, 59-63.

468. Feedback control of the arachidonate cascade in osteoblastic cells by 15-deoxy-Δ12,14-prostaglandin J2,

J Clin Biochem Nutr., 42, 2008, 64-69.

469. Molecular Characterization of a Variat Virus That Caused De Novo Hepatitis B Without Elevation of

Hepatitis B Surface Antigen Ater Chemotherapy With Rituximab, J Med Virol., 80, 2008, 2069-2078.

470. Prophylactic effect of rebamipide on aspirin-induced gastric lesions and disruption of tight junctional

protein zonula occludens-1, J Pharmacol Sci., 106, 2008, 469-477.

471. Astaxanthin protects mesangial cells from hyperglycemia-induced oxidative signaling, J Cell Biochem.,

103, 2008, 1925-1937.

472. Prevention of indomethacin-induced gastric mucosal injury in Helicobacter pylori-negative healthy

volunteers: a comparison study rebamipide vs famotidine, J Clin Biochem Nutr., 43, 2008, 34-40.

473. Helicobacter pylori infection and arterial stiffness in patients with type 2 diabetes mellitus, Metabolism.,

57, 2008, 1760-1764.

474. Bone stiffness in men with type 2 diabetes mellitus, Metabolism., 57, 2008, 1691-1695.

475. Bone mass and bone resorption in postmenopausal women with type 2 diabetes mellitus, Metabolism.,

57, 2008, 940-945.

476. Serum uric acid is associated with microalbuminuria and subclinical atherosclerosis in men with type 2

diabetes mellitus, Metabolism., 57, 2008, 625-629.

477. Association between serum estradiol concentrations and carotid atherosclerosis in men with type 2

diabetes mellitus, Metabolism., 57, 2008, 285-289.

478. Alteration of the expression profiles of acidic mucin, sialytransferase, and sulfotransferases in the

intestinal epithelium of rats infected with the nematode Nippostrongylus brasiliensis , Parasitol Res.,

103, 2008, 1427-1434.

479. Infrequent amplification of JUN in hepatocellular carcinoma, Anticancer Res., 29, 2009, 4989-4994.

480. Inhibitory effect of serotonin derivatives on high glucose-induced adhesion and migration of monocytes

on human aortic endothelial cells, Br J Nutr, 102, 2009, 264-272.

481. A novel amplification target, ARHGAP5, promotes cell spreading and migration by negatively regulating

RhoA in Huh-7 hepatocellular carcinoma cells, Cancer Lett., 275, 2009, 27-34.

482. Endoscopic Injection Sclerotherapy with Ethanolamine Oleate with Iopamidol for Esophagojejunal

Varices in Idiopathic Portal Hypertension, Dig Dis Sci., 54, 2009, 1592-1596.

483. Heat-shock protein 70-overexpressing gastric epithelial cells are resistant to indomethacin-induced

apoptosis, Digestion., 79, 2009, 243-250.

484. Endoscopic submucosal dissection for colorectal tumors: technical difficulties and rate of perforation,

Endoscopy., 41, 2009, 758-761.

485. Effects of diesel exhaust particles on antigen-presenting cells and antigen-specific Th immunity in mice,

Exp Biol Med., 234, 2009, 200-209.

Page 25: Publications of Dr. Toshikazu Yoshikawa...Effect of levamisole on the complement system, Jpn J Clin Pharmacol Ther., 11, 1980, 161-170. 14. Enzyme immunoassay of pancreatic oncofetal

486. In vivo real-time measurement of superoxide anion radical with a novel electrochemical sensor, Free

Radic Biol Med., 47, 2009, 1039-1048.

487. ERK5 is a target for gene amplification at 17p11 and promotes cell growth in hepatocellular carcinoma

by regulation mitotic entry, Genes Chromosomes Cancer., 48, 2009, 109-120.

488. Length of Vancomycin Administration for Treatment of Clostridium Difficile-Associated Diarrhea May

Depend on Presentation of Colonic Ulcer , Hepatogastroenterology., 56, 2009, 313-316.

489. MELD Score, Child-Pugh Score, and Decreased Album as Risk Factors for Gastric Variceal Bleeding ,

Hepatogastroenterology., 56, 2009, 1552-1556.

490. Antitumor effect of petreatment for colon cancer cells with hyperthermia plub geranylacetone in

experimental metastasis models and a subcutaneous tumor model of colon cancer in mice, Int J

Hyperthermia., 25(2), 2009, 141-149.

491. Outcoming of endoscopic submucosal dissection for colorectal tumors in elderly people, Int. J. Colorectal

Dis, 2009, 455-61.

492. Effect of hyperthermia combined with gemcitabine on apoptotic cell death in cultured human pancreatic

cancer cell lined, Int. J. Hyperthermia, 25(3), 2009, 210-219.

493. Identification of inflammation-related proteins in a murine colitis model by 2D fluorescence difference

gel electrophoresis and mass spectrometry, J Gastroenterol Hepatol., 25

Suppl.1, 2009, S144-S148.

494. Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells

through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and oxidation of

kelch-like ECH-associating protein 1, J Pharmacol Exp Ther., 331(1), 2009, 255-264.

495. Inhibition of Bach1 Ameliorates Indomethacin-Induced Intestinal Injury in Mice, J Physiol Pharmacol.,

60

Suppl 7, 2009, 149-54.

496. Zinc finger protein 28 as a novel melanoma-related molecule, J Dermatol Sci., 55

(1), 2009, 68-70.

497. Phosphodiesterase isoymes involved in regulating acid secretion in the isolated mouse stomach, J Physiol

Pharmacol., 60(Supple 7), 2009, 183-190.

498. Relaxant effect of microtitan via regulation of autonomic nerve activity in mice , Life Sci., 85, 2009, 408-

411.

499. Oxidative stress may enhance the malignant potential of human hepatocellular carcinoma by telomerase

activation, Liver Int., 2009, 846-856.

500. Defective expression of polarity protein PAR-3 gene (PARD3) in esophageal squamous cell carcinoma,

Oncogene, 28, 2009, 2910-2918.

501. Iron restriction improves type 2 diabetes mellituss in Otsuka Long-Evans Tokushima fatty rats, Am J

Physiol Endocrimol Metab., 298, 2010, E1140-E1149.

502. Carbon monoxide enhance colonic epithelial restitution via FGF15 derived from colonic myofibroblasts,

Biochem Biophys Res Commun., 391, 2010, 1122-1126.

503. Regular exercise reduces colon tumorigenesis associated with suppression of iNOS, Biochem Biophys

Res Commun. , 399, 2010, 14-19.

504. Pro-Oxidant Action of Pyrroloquinoline Quinone: Characterization of Protein Oxidant Modifications ,

Biosci Biotechnol Biochem., 74(3), 2010, 663-666.

Page 26: Publications of Dr. Toshikazu Yoshikawa...Effect of levamisole on the complement system, Jpn J Clin Pharmacol Ther., 11, 1980, 161-170. 14. Enzyme immunoassay of pancreatic oncofetal

505. PEG10 is a probable target for the amplification at 7q21 detected in hepatocellular carcinoma, Cancer

Genet Cytogenet., 198, 2010, 118-125.

506. SOX2 identified as a target gene for the amplification at 3q26 that is frequently detected in esophageal

squamous cell carcinoma, Cancer Genet Cytogenet., 202, 2010, 82-93.

507. Management of Recurrence of Symptoms of Gastroesophageal Reflux Disease: Synergistic Effect of

Rebamipide with 15 mg Lansoprazole , Dig Dis Sci., 55, 2010, 3393-3398.

508. Successful endoscopic hemostasis for ruptured duodenal varices after balloon-occluded retrograde

transvenous obliteration , Dig Endosc., 22, 2010, 329-333.

509. Successful endoxcopic injection sclerotherapy of high-risk gastroesophageal varices in a cirrhotic patient

with hemophilia A, Gastroenterol Res Pract., 2010, 1-5.

510. Relapse of hepatitis C in a peylated-interferon-α-2b plus ribavirin-treated sustained virological

responder, Hepatol Res., 40, 2010, 654-660.

511. Lower circulating levels of dehydroepiandrosterone, independent of insulin resistance, is an important

determinant of severity of non-alcohlic steatohepatitis in Japanese patients, Hepatol Res., 40, 2010, 901-

910.

512. Evaluation of autofluorescence colonoscopy for diagnosis of superficial colorectal neoplastic lesions, Int

J Colorectal Dis., 2010, 811-6.

513. Outcome of endoscopic submucosal dissection for colorectal tumors in elderly people, Int J Colorectal

Dis., 25(4), 2010, 455-461.

514. Epigenetic silencing of RELN in gastric cancer, Int. J. Oncol., 36, 2010, 85-92.

515. Reactive oxygen species-quenching and anti-apoptotic effect of polaprezincon on indomethain-induced

small intestinal epithelial cell injury, J Gastroenterol., 45, 2010, 692-702.

516. Early-stage blocking of notch signaling inhibits the depletion of goblet cells in dextran sodium sulfate-

induced colitis in mice, J Gastroenterol., 45, 2010, 608-617.

517. Steatosis and hepatic expression of genes regulating lipid metabolism in Japanese patients infected with

hepatitis C virus , J Gastroenterol., 45, 2010, 95-104.

518. Chemical and immunochemical detection of 8-halogenated deoxyguanosines at early stage inflammation,

J Biol Chem., 2010, 9282-91.

519. Hepatic senescene marker protein-30 is involved in the progression of nonalcoholic fatty liver disease, J

Gastroenterol., 45(4), 2010, 426-434.

520. Increased expression of micro RNA in the inflamed colonic mucosa of patients with active ulcerative

coloitis, J Gastroenterol Hepatol., 25

Suppl 7, 2010, S129-S133.

521. Ecabet sodium promotes the healing of trinitrobenzene-sulfonic-acid induced ulceration by enhanced

restitution of intestinal epithelial dells, J Gastroenterol Hepatol., 25, 2010, 1259-1265.

522. Statistical Identification of Predictors for Peripheral Neuropathy Associated with Administration of

Bortezomib, Taxanes, Oxaliplatin or Vincristine Using Ordered Logistic Regression Analysis, J

Gastroenterol Hepatol., 2010, 877-881.

523. Association between capacity of interferon-α production and metabolic parameters, J Interferon Cytokine

Res., 30(7), 2010, 35-38.

524. Silver nanoparticles as a safe preservative for use in cosmetics, Nanomedicine., 6, 2010, 570-574.

525. Nuclear size measurement is a Simple method for the assessment of hepatocellular aging in non-

Page 27: Publications of Dr. Toshikazu Yoshikawa...Effect of levamisole on the complement system, Jpn J Clin Pharmacol Ther., 11, 1980, 161-170. 14. Enzyme immunoassay of pancreatic oncofetal

alcoholic fatty liver disease: Comparison with telomere-specific quantitative FISH and p21

immunohistochemistry , Pathol Int., 60, 2010, 175-183.

526. Safe procedure in endoscopic submucosal dissection for colorectal tumors focused on preventing

complications, World J Gastroenterol., 16(14), 2010, 1688-1695.

527. Efficient hemostatic methos for endoscopic submucosal dissection of colorectal tumors, World J

Gastroenterol., 16(33), 2010, 4180-4186.

528. Oxidative stress-induced posttranslational modification of TRPV1 expressed in esophageal epithelial

cells. , Am J Physiol Gastrointest Liver Physiol. , 301, 2011, G230-8.

529. Regular exercise prevents high-sucrose diet-induced fatty liver via improvement of hepatic lipid

metabolism. , Biochem Biophys Res Commun., 413, 2011, 330-335.

530. Heat-shock protein 27 (Hsp27) as a target of methylglyoxal in gastrointestinal cancer. , Biochim Biophys

Acta., 1812, 2011, 769-781.

531. Daikenchuto, a Kampo medicine, regulates intestinal fibrosis by inhibiting heat shock protein 47

expression in a rat colitis model. , Biol Pharm Bull., 34, 2011, 1659-1665.

532. Relationship between circulating cytokine levels and physical or psychological functioning in patients

with advanced cancer, Clin Biochem., 2011, 207-11.

533. Factors predicting requirement of high-dose transdermal fentanyl in opioid switching from oral

morphine or oxycodone in patients with cancer pain. , Clin J Pain. , 27(8), 2011, 664-667.

534. Endogenous hydrogen sulfide Is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis

in mice. , Dig Dis Sci., 56, 2011, 1379-1386.

535. FGF19 Protects Colonic Epithelial Cells against Hydrogen Peroxide, Digestion., 83, 2011, 180-183.

536. Carbon monoxide liberated from carbon monoxide releasing molecule exerts an anti-inflammatory effect

on dextran sulfate sodium-induced colitis in mice

, Dig Dis Sci., 56, 2011, 1663-1671.

537. Sedation with dexmedetomidine hydrochloride during endoscopic submucosal dissection of gastric

cancer , Dig Endosc., 23, 2011, 176-181.

538. Use of endoscopic nasobiliary drainage tube for treating mediastinitis caused by insertion of an

esophageal self-expanding metal stent., Endoscopy., 43(Suppl 2), 2011, E223-224.

539. Adoptive cellular therapy enhances the helper T cell response and reduces the number of regulatory T

cells. , Exp Therap Med ., 2, 2011, 737-743.

540. Suppression of indomethacin-induced apoptosis in the small intestine due to Bach1 deficiency. , Free

Radic Res., 45, 2011, 717-727.

541. Multifaceted assessment of chronic gastritis: a study of correlations between serological, endoscopic, and

histological diagnostics. , Gastroenterol Res Pract., 2011.

542. Bleeding from major and minor duodenal papillae due to hemosuccus pancreaticus confirmed with side-

view gastroduodenal endoscopy. , Indian J Gastroenterol. , 2011.

543. Long fish tapeworm in the intestine: an in situ observation by capsule endoscopy. , Intern Med. , 50(4),

2011, 325-327.

544. Role of tumor necrosis factor-α in the pathogenesis of indomethacin-induced small intestinal injury in

mice. , Int J Mol Med., 27(3), 2011, 353-359.

545. Heat shock protein 70-dependent protective effect of polaprezinc on acetylsalicylic acid-induced apoptosis

of rat intestinal epithelial cells. , J Clin Biochem Nutr., 2011.

Page 28: Publications of Dr. Toshikazu Yoshikawa...Effect of levamisole on the complement system, Jpn J Clin Pharmacol Ther., 11, 1980, 161-170. 14. Enzyme immunoassay of pancreatic oncofetal

546. Identification of dihalogenated-modified proteins involved in the pathogenesis of indomethacin-induced

intestinal injuries in rats. , J Clin Biochem Nutr ., 48, 2011, 178–182.

547. Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease, J Gastroenterol.,

46, 2011, 101-107.

548. Efficacy of magnifying endoscopy with flexible spectral imaging color enhancement in the diagnosis of

colorectal tumors , J Gastroenterol., 46, 2011, 65-72.

549. Impact of amino acid substitutions in hepatitis C virus genotype 1b core region on liver steatosis and

glucose tolerance in non-cirrhotic patients without overt diabetes , J Gastroenterol Hepatol., 26(5), 2011,

836-842.

550. Identification of dihalogenated proteins in rat intestinal mucosa injured by indomethacin, J Clin

Biochem Nutr., 48(2), 2011, 178-182.

551. Reduced small-intestinal injury induced by indomethacin in interleukin-17A-deficient mice, J

Gastroenterol Hepatol., 26, 2011, 398-404.

552. Efficacy of hyaluronic acid in endoscopic mucosal resection of colorectal tumors , J Gastroenterol

Hepatol., 26, 2011, 286-291.

553. Nonalcoholic steatohepatitis and increased risk of chronic kidney disease , Metabolism., 60, 2011, 735-

739.

554. Identification of Treatment Efficacy-Related Host Factors in Chronic Hepatitis C by ProteinChip Serum

Analysis , Mol Med., 17(1-2), 2011, 70-78.

555. Dietary whey hydrolysate with exercise alters the plasma protein profile: A comprehensive protein

analysis. , Nutrition, 27, 2011, 687-692.

556. Exercise-induced muscle damage impairs insulin signaling pathway associated with IRS-1 oxidative

modification. , Physiol Res., 2011.

557. Selecting Patients for Hyperthermia Treatment Based on Patient Backgrounds , Thermal Med., 27(2),

2011, 51-60.

558. A multicenter study of the efficacy and safety of leukocytapheresis therapy without concomitant systemic

steroid treatment in patients with active ulcerative colitis , Transfus Apher Sci., 44, 2011, 113-117.

559. Rebamipide promotes healing of colonic ulceration through enhanced epithelial restitution, World J

Gastroenterol., 17(33), 2011, 3802-3809.

560. Acetyl salicylic acid induces damage to intestinal epithelial cells by oxidation-related modifications of

ZO-1, Am J Physiol Gastrointest Liver Physiol. , 303, 2012, G927-G936.

561. Relationship between circulating cytokine levels and physical or psychological functioning in patients

with advanced cancer , Clin Biochem., 45, 2012, 207-211.

562. The Role of Methylglyoxal-Modified Proteins in Gastric Ulcer Healing , Curr Med Chem., 19, 2012, 137-

144.

563. Role of Nociceptors/Neuropeptides in the Pathogenesis of Visceral Hypersensitivity of Nonerosive Reflux

Disease, Dig Dis Sci., 2012.

564. Recognition of Endoscopic Diagnosis in Differentiated-Type Early Gastric Cancer by Flexible Spectral

Imaging Color Enhancement with Indigo Carmine , Digestion., 86, 2012, 161-170.

565. Usefuness of a noverl observation method using a small diamter rigid telescope through the gastrostomy

catheter at exchange. , Dig Endosc., 2012.

566. A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis

Page 29: Publications of Dr. Toshikazu Yoshikawa...Effect of levamisole on the complement system, Jpn J Clin Pharmacol Ther., 11, 1980, 161-170. 14. Enzyme immunoassay of pancreatic oncofetal

via regular exercise , Gut., 2012.

567. The detection of surface patterns by flexible spectral imaging color enhancement without magnification

for diagnosis of colorectal polyps , Int J Colorectal Dis., 27, 2012, 605-611.

568. Phase II Trial of combined regional hyperthermia and gemcitabine for locally advanced or metastatic

pancreatic cancer , Int. F. Hyperthermia , 28(7), 2012, 597-604.

569. Atrophic gastritis is associated with coronary artery disease. , J Clin Biochem Nutr., 51(1), 2012, 39-41.

570. Rebamipide ameliorates indomethacin-induced small intestinal injury in rats via the inhibition of matrix

metalloproteinases activity , J Gastroenterol Hepatol., 27, 2012, 1816-1824.

571. Hemopexin is upregulated in rat intestinal mucosa injured by indomethacin , J Gastroenterol Hepatol.,

27, 2012, 70-75.

572. Plasma ghrelin isoforms and gastric ghrelin O-acyltransferase expression are influenced by Helicobacter

pylori status , Nutrition, 28, 2012, 967-972.

573. Exercise-Induced Muscle Damage Impairs Insulin Signaling Pathway Associated With IRS-1 Oxidative

Modification , Physiol Res., 61, 2012, 81-88.

574. Muscle-enriched microRNA miR-486 decreases in circulation in response to exercise in young men ,

Front Physiol., 4(80), 2013.

575. BTB and CNC Homolog 1 (Bach1) Deficiency Ameliorates TNBS Colitis in Mice: Role of M2 Macrophages

and Heme Oxygenase-1 , Inflamm Bowel Dis., 19(4), 2013, 740-753.

576. Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma, Int. J. Oncol., 2013.

577. Role of metallothionein in murine experimental colitis , Int J Mol Med., 31, 2013, 1037-1046.

578. Titanium-treated surroundings attenuate psychological stress associated with autonomic nerve

regulation in office workers with daily emotional stress , Physiol Behav., 2013.

579. Azuma K, Uchiyama I, Tanigawa M, Bamba I, Azuma M, Takano H, Yoshikawa T, Sakabe K. Assessment

of cerebral blood flow in patients with multiple chemical sensitivity using near-infrared spectroscopy--

recovery after olfactory stimulation: a case-control study. Environ Health Prev Med 20(3): 185-194, 2015.

580. Otsuki T, Maeda S, Mukai J, Ohki M, Nakanishi M, Yoshikawa T. Association between plasma sLOX-1

concentration and arterial stiffness in middle-aged and older individuals. J Clin Biochem Nutr 57(2):

151-155, 2015.

581. Takeda Y, Harada Y, Yoshikawa T and Dai P. Direct conversion of human fibroblasts to brown adipocytes

by small chemical compounds. Sci. Rep. 7: 4304 (DOI:10.1038/s41598-017-04665-x) , 2017.

582. Morita M, Naito Y, Niki E, Yoshikawa T. Antioxidant action of fermented grain food supplement:

Scavenging of peroxyl radicals and inhibition of plasma lipid oxidation induced by multiple oxidants.

Food Chem. 237:574-580, 2017

583. Wakao J, Kishida T, Fumino S, Kimura K, Yamamoto K, Kotani SI, Mizushima K, Naito Y, Yoshikawa T,

Tajiri T, Mazda O. Efficient direct conversion of human fibroblasts into myogenic lineage induced by co-

transduction with MYCL and MYOD1. Biochem Biophys Res Commun. 488(2): 368-373, 2017.

584. Takeda Y, Harada Y, Yoshikawa T and Dai P. Chemical compound-based direct reprogramming for future

clinical applications. Biosci Rep. 38(3): BSR20171650. (doi: 10.1042/BSR20171650) , 2018.