7/24/2019 Protein and Urea Production

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Protein and urea production1. Deamination

Removal of amino groups

from amino acids by

transamination2. Urea formation by the

liver

2NH3 !"2urea H2#

3. $he %eto&acid produced

can'

(nter the citric acid cycle

to be metabolised to form

)$P

Used by the liver to

synthesi*e

glucose+glycogen

,gluconeogenesis-

!onverted into acetyl&co)

to be polymeri*ed to form

fatty acids ,%etogenesis-

Urea diuses out of

the liver to be

e/creted by the%idneys.